locus-tag	class	description
FDP16_RS00010	COG0592	DNA-directed DNA polymerase activity
FDP16_RS00025	COG0012	GTP binding
FDP16_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
FDP16_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FDP16_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDP16_RS00055	COG0037	tRNA processing
FDP16_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDP16_RS00210	COG3942	CHAP domain
FDP16_RS00220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDP16_RS00230	COG4509	Sortase family
FDP16_RS00235	COG0436	Aminotransferase
FDP16_RS00240	COG1381	Involved in DNA repair and RecF pathway recombination
FDP16_RS00245	COG0416	fatty acid biosynthetic process
FDP16_RS00250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDP16_RS00255	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FDP16_RS00260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FDP16_RS00275	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FDP16_RS00280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDP16_RS00295	COG3942	CHAP domain
FDP16_RS00300	COG0151	Belongs to the GarS family
FDP16_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FDP16_RS00325	COG1794	racemase activity, acting on amino acids and derivatives
FDP16_RS00350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FDP16_RS00355	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDP16_RS00365	COG2376	Dihydroxyacetone kinase
FDP16_RS00370	COG1461	Dihydroxyacetone kinase
FDP16_RS00375	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FDP16_RS00380	COG2188	Transcriptional regulator
FDP16_RS00390	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP16_RS00400	COG3716	PTS system mannose fructose sorbose family IID component
FDP16_RS00410	COG2222	sugar isomerase
FDP16_RS00415	COG3684	Belongs to the aldolase LacD family
FDP16_RS00425	COG2255	four-way junction helicase activity
FDP16_RS00435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FDP16_RS00475	COG1012	belongs to the aldehyde dehydrogenase family
FDP16_RS00475	COG1454	alcohol dehydrogenase
FDP16_RS00485	COG3458	cephalosporin-C deacetylase activity
FDP16_RS00490	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FDP16_RS00495	COG3842	ATPase activity
FDP16_RS00505	COG1175	transmembrane transport
FDP16_RS00510	COG0395	ABC-type sugar transport system, permease component
FDP16_RS00525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDP16_RS00550	COG1269	ATP hydrolysis coupled proton transport
FDP16_RS00555	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FDP16_RS00565	COG1527	subunit (C
FDP16_RS00570	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
FDP16_RS00580	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FDP16_RS00585	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FDP16_RS00590	COG1394	ATPase activity, coupled to movement of substances
FDP16_RS00605	COG1523	belongs to the glycosyl hydrolase 13 family
FDP16_RS00610	COG1609	Transcriptional regulator
FDP16_RS00615	COG1640	4-alpha-glucanotransferase
FDP16_RS00620	COG0058	SHG alpha-glucan phosphorylase activity
FDP16_RS00630	COG1780	Probably involved in ribonucleotide reductase function
FDP16_RS00635	COG0018	arginyl-trna synthetase
FDP16_RS00640	COG1438	arginine binding
FDP16_RS00645	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FDP16_RS00665	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDP16_RS00675	COG1395	domain, Protein
FDP16_RS00680	COG0632	four-way junction helicase activity
FDP16_RS00685	COG2818	Glycosylase
FDP16_RS00705	COG1136	(ABC) transporter
FDP16_RS00720	COG1058	Belongs to the CinA family
FDP16_RS00720	COG1546	Belongs to the CinA family
FDP16_RS00725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FDP16_RS00730	COG1393	Belongs to the ArsC family
FDP16_RS00745	COG4472	Bacterial protein of unknown function (DUF965)
FDP16_RS00750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDP16_RS00755	COG3906	Belongs to the UPF0473 family
FDP16_RS00760	COG0285	dihydrofolate synthase activity
FDP16_RS00770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDP16_RS00785	COG1328	CTP reductase activity
FDP16_RS00805	COG0602	queuosine metabolic process
FDP16_RS00810	COG1316	TRANSCRIPTIONal
FDP16_RS00815	COG4464	protein tyrosine phosphatase activity
FDP16_RS00820	COG3944	biosynthesis protein
FDP16_RS00840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDP16_RS00845	COG1216	Glycosyl transferase, family 2
FDP16_RS00855	COG3475	LICD family
FDP16_RS00865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FDP16_RS00885	COG0564	pseudouridine synthase activity
FDP16_RS00890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDP16_RS00895	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FDP16_RS00925	COG0052	Belongs to the universal ribosomal protein uS2 family
FDP16_RS00930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FDP16_RS00940	COG4463	regulation of RNA biosynthetic process
FDP16_RS00965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FDP16_RS00970	COG3201	nicotinamide mononucleotide transporter
FDP16_RS00985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDP16_RS00990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FDP16_RS00995	COG1397	ADP-ribosylglycohydrolase
FDP16_RS01010	COG1181	Belongs to the D-alanine--D-alanine ligase family
FDP16_RS01010	COG2918	glutathione biosynthetic process
FDP16_RS01015	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDP16_RS01030	COG0166	Belongs to the GPI family
FDP16_RS01050	COG2171	N-acyltransferase activity
FDP16_RS01055	COG1473	amidohydrolase
FDP16_RS01060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDP16_RS01070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FDP16_RS01075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FDP16_RS01080	COG1132	(ABC) transporter
FDP16_RS01085	COG1132	(ABC) transporter
FDP16_RS01090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FDP16_RS01100	COG0756	dUTP diphosphatase activity
FDP16_RS01150	COG3711	transcriptional antiterminator
FDP16_RS01155	COG2261	transglycosylase associated protein
FDP16_RS01190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDP16_RS01200	COG0137	argininosuccinate synthase activity
FDP16_RS01205	COG0165	Argininosuccinate lyase
FDP16_RS01210	COG0594	ribonuclease P activity
FDP16_RS01220	COG1847	R3H domain protein
FDP16_RS01230	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FDP16_RS01240	COG3655	Transcriptional regulator
FDP16_RS01260	COG0084	hydrolase, TatD family'
FDP16_RS01275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDP16_RS01295	COG1162	GTPase activity
FDP16_RS01305	COG1564	THIamine pyrophosphokinase
FDP16_RS01315	COG3481	metal-dependent phosphohydrolase, HD sub domain
FDP16_RS01320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FDP16_RS01330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FDP16_RS01335	COG0049	tRNA binding
FDP16_RS01340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FDP16_RS01350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FDP16_RS01370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP16_RS01375	COG0765	amino acid transport
FDP16_RS01380	COG0765	amino acid transport
FDP16_RS01385	COG1126	abc transporter atp-binding protein
FDP16_RS01500	COG3037	sugar-specific permease SgaT UlaA
FDP16_RS01510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP16_RS01520	COG3623	hexulose-6-phosphate isomerase
FDP16_RS01540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDP16_RS01550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDP16_RS01555	COG4589	Belongs to the CDS family
FDP16_RS01560	COG0750	zinc metalloprotease
FDP16_RS01565	COG0442	prolyl-tRNA aminoacylation
FDP16_RS01595	COG2309	aminopeptidase activity
FDP16_RS01605	COG0242	peptide deformylase activity
FDP16_RS01615	COG1187	pseudouridine synthase activity
FDP16_RS01620	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FDP16_RS01625	COG2267	carboxylic ester hydrolase activity
FDP16_RS01640	COG3118	belongs to the thioredoxin family
FDP16_RS01645	COG1164	Oligoendopeptidase f
FDP16_RS01650	COG0477	Major facilitator Superfamily
FDP16_RS01655	COG1185	polyribonucleotide nucleotidyltransferase activity
FDP16_RS01660	COG1045	serine acetyltransferase
FDP16_RS01680	COG0215	cysteine-tRNA ligase activity
FDP16_RS01685	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FDP16_RS01700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDP16_RS01705	COG3688	RNA-binding protein containing a PIN domain
FDP16_RS01715	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FDP16_RS01720	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FDP16_RS01765	COG1301	dicarboxylic acid transport
FDP16_RS01775	COG5492	domain, Protein
FDP16_RS01775	COG3583	domain protein
FDP16_RS01775	COG1621	beta-fructofuranosidase activity
FDP16_RS01780	COG0789	Transcriptional regulator
FDP16_RS01780	COG4978	Transcriptional regulator
FDP16_RS01785	COG3804	dihydrodipicolinate reductase
FDP16_RS01795	COG3830	Belongs to the UPF0237 family
FDP16_RS01800	COG2848	UPF0210 protein
FDP16_RS01810	COG0588	phosphoglycerate mutase activity
FDP16_RS01815	COG1876	peptidase activity
FDP16_RS01840	COG1420	regulation of RNA biosynthetic process
FDP16_RS01845	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FDP16_RS01850	COG0443	Heat shock 70 kDa protein
FDP16_RS01860	COG0484	heat shock protein binding
FDP16_RS01865	COG3064	Membrane
FDP16_RS01870	COG0101	tRNA pseudouridine synthase activity
FDP16_RS01875	COG0351	phosphomethylpyrimidine kinase
FDP16_RS01880	COG4720	Psort location CytoplasmicMembrane, score
FDP16_RS01885	COG4475	Protein of unknown function (DUF436)
FDP16_RS01890	COG0544	peptidyl-prolyl cis-trans isomerase activity
FDP16_RS01895	COG3343	RNA polymerase activity
FDP16_RS01905	COG0504	CTP synthase activity
FDP16_RS01920	COG0191	fructose-bisphosphate aldolase activity
FDP16_RS01960	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FDP16_RS01980	COG1131	(ABC) transporter
FDP16_RS01990	COG4585	Histidine kinase
FDP16_RS01995	COG2197	response regulator
FDP16_RS02000	COG0028	Belongs to the TPP enzyme family
FDP16_RS02005	COG0440	acetolactate synthase activity
FDP16_RS02010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FDP16_RS02015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDP16_RS02030	COG1126	abc transporter atp-binding protein
FDP16_RS02035	COG0765	amino acid transport
FDP16_RS02045	COG1968	undecaprenyl-diphosphatase activity
FDP16_RS02050	COG4862	establishment of competence for transformation
FDP16_RS02055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FDP16_RS02065	COG0719	Fe-S assembly protein
FDP16_RS02070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FDP16_RS02080	COG0719	Fe-S assembly protein
FDP16_RS02085	COG1686	Belongs to the peptidase S11 family
FDP16_RS02090	COG4166	transmembrane transport
FDP16_RS02095	COG4166	transmembrane transport
FDP16_RS02100	COG4166	transmembrane transport
FDP16_RS02105	COG0601	transmembrane transport
FDP16_RS02110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDP16_RS02115	COG0444	Belongs to the ABC transporter superfamily
FDP16_RS02120	COG4608	Belongs to the ABC transporter superfamily
FDP16_RS02155	COG1024	Enoyl-CoA hydratase
FDP16_RS02160	COG1846	Transcriptional regulator
FDP16_RS02165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FDP16_RS02180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FDP16_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
FDP16_RS02190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FDP16_RS02200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FDP16_RS02205	COG0439	Biotin carboxylase
FDP16_RS02210	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FDP16_RS02215	COG0825	malonyl-CoA metabolic process
FDP16_RS02235	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FDP16_RS02260	COG3716	PTS system mannose fructose sorbose family IID component
FDP16_RS02265	COG3715	PTS system
FDP16_RS02275	COG1064	alcohol dehydrogenase
FDP16_RS02280	COG0561	phosphatase activity
FDP16_RS02290	COG2252	PERMEase
FDP16_RS02295	COG0802	atpase or kinase
FDP16_RS02300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDP16_RS02305	COG1316	TRANSCRIPTIONal
FDP16_RS02315	COG0537	adenosine 5'-monophosphoramidase activity
FDP16_RS02320	COG1131	(ABC) transporter
FDP16_RS02335	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDP16_RS02340	COG0779	Required for maturation of 30S ribosomal subunits
FDP16_RS02345	COG0195	Participates in both transcription termination and antitermination
FDP16_RS02350	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FDP16_RS02360	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FDP16_RS02365	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FDP16_RS02380	COG0656	L-ascorbic acid biosynthetic process
FDP16_RS02400	COG3328	transposase activity
FDP16_RS02425	COG0752	glycyl-tRNA synthetase alpha subunit
FDP16_RS02430	COG0751	glycine-tRNA ligase activity
FDP16_RS02460	COG0275	rRNA processing
FDP16_RS02470	COG0768	penicillin binding
FDP16_RS02475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FDP16_RS02480	COG0513	Belongs to the DEAD box helicase family
FDP16_RS02485	COG0765	amino acid transport
FDP16_RS02490	COG1126	abc transporter atp-binding protein
FDP16_RS02500	COG0492	ferredoxin-NADP+ reductase activity
FDP16_RS02505	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FDP16_RS02510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDP16_RS02515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDP16_RS02535	COG3579	cysteine-type endopeptidase activity
FDP16_RS02540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDP16_RS02545	COG3331	DNA recombination
FDP16_RS02550	COG4474	Belongs to the UPF0398 family
FDP16_RS02555	COG3599	regulation of cell shape
FDP16_RS02565	COG0116	Belongs to the methyltransferase superfamily
FDP16_RS02575	COG1854	S-ribosylhomocysteine lyase activity
FDP16_RS02580	COG1418	mRNA catabolic process
FDP16_RS02585	COG0194	GDP metabolic process
FDP16_RS02590	COG1758	RNA polymerase activity
FDP16_RS02595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FDP16_RS02600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FDP16_RS02605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FDP16_RS02605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FDP16_RS02610	COG0631	protein serine/threonine phosphatase activity
FDP16_RS02615	COG0515	serine threonine protein kinase
FDP16_RS02615	COG2815	serine threonine protein kinase
FDP16_RS02625	COG4585	Histidine kinase
FDP16_RS02640	COG1185	polyribonucleotide nucleotidyltransferase activity
FDP16_RS02650	COG1739	Uncharacterized protein family UPF0029
FDP16_RS02670	COG1040	competence protein
FDP16_RS02755	COG3557	Belongs to the UPF0374 family
FDP16_RS02760	COG2137	regulation of response to DNA damage stimulus
FDP16_RS02765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FDP16_RS02770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FDP16_RS02775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FDP16_RS02780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FDP16_RS02805	COG0519	Catalyzes the synthesis of GMP from XMP
FDP16_RS02835	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FDP16_RS02845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP16_RS02845	COG1263	PTS System
FDP16_RS02845	COG2190	(PTS) system
FDP16_RS02855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FDP16_RS02865	COG1484	DNA-dependent DNA replication
FDP16_RS02875	COG1160	GTP binding
FDP16_RS02890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDP16_RS02905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FDP16_RS02910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDP16_RS02915	COG2357	RelA SpoT domain protein
FDP16_RS02920	COG0745	RESPONSE REGULATOR receiver
FDP16_RS02925	COG5002	protein histidine kinase activity
FDP16_RS02935	COG1254	Belongs to the acylphosphatase family
FDP16_RS02940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDP16_RS02965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDP16_RS02970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FDP16_RS02985	COG4974	Belongs to the 'phage' integrase family
FDP16_RS02990	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FDP16_RS02995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FDP16_RS03000	COG1187	pseudouridine synthase activity
FDP16_RS03005	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FDP16_RS03010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDP16_RS03015	COG0569	domain protein
FDP16_RS03025	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FDP16_RS03030	COG0671	phosphoesterase, PA-phosphatase related
FDP16_RS03040	COG1242	4 iron, 4 sulfur cluster binding
FDP16_RS03045	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FDP16_RS03060	COG1119	ATPase activity
FDP16_RS03065	COG0628	permease
FDP16_RS03070	COG1253	flavin adenine dinucleotide binding
FDP16_RS03105	COG2188	Transcriptional regulator
FDP16_RS03110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP16_RS03110	COG1263	PTS System
FDP16_RS03115	COG0366	Alpha amylase catalytic
FDP16_RS03125	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FDP16_RS03130	COG1227	inorganic diphosphatase activity
FDP16_RS03155	COG3237	CsbD-like
FDP16_RS03165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FDP16_RS03170	COG2244	polysaccharide biosynthetic process
FDP16_RS03190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FDP16_RS03195	COG3935	DnaD domain protein
FDP16_RS03225	COG4974	Belongs to the 'phage' integrase family
FDP16_RS03230	COG0626	cystathionine gamma-synthase activity
FDP16_RS03235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FDP16_RS03240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FDP16_RS03245	COG0740	serine-type endopeptidase activity
FDP16_RS03250	COG4471	UPF0298 protein
FDP16_RS03255	COG0683	leucine binding
FDP16_RS03280	COG0517	IMP dehydrogenase activity
FDP16_RS03285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FDP16_RS03290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FDP16_RS03295	COG0470	DNA polymerase III
FDP16_RS03300	COG4467	Involved in initiation control of chromosome replication
FDP16_RS03310	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FDP16_RS03315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDP16_RS03320	COG1393	Belongs to the ArsC family
FDP16_RS03325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDP16_RS03340	COG0708	Exodeoxyribonuclease III
FDP16_RS03355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDP16_RS03355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDP16_RS03365	COG1349	DNA-binding transcription factor activity
FDP16_RS03375	COG0698	ribose 5-phosphate isomerase
FDP16_RS03380	COG1105	Belongs to the carbohydrate kinase PfkB family
FDP16_RS03385	COG3684	Belongs to the aldolase LacD family
FDP16_RS03390	COG3711	transcriptional antiterminator
FDP16_RS03405	COG2723	6-phospho-beta-galactosidase activity
FDP16_RS03410	COG3655	Transcriptional regulator
FDP16_RS03440	COG0745	RESPONSE REGULATOR receiver
FDP16_RS03445	COG5002	protein histidine kinase activity
FDP16_RS03475	COG1136	(ABC) transporter
FDP16_RS03480	COG0577	efflux transmembrane transporter activity
FDP16_RS03485	COG1131	(ABC) transporter
FDP16_RS03495	COG3279	Response regulator of the LytR AlgR family
FDP16_RS03520	COG1309	transcriptional regulator
FDP16_RS03565	COG1136	(ABC) transporter
FDP16_RS03570	COG0577	efflux transmembrane transporter activity
FDP16_RS03575	COG0531	amino acid
FDP16_RS03615	COG1028	Short-chain dehydrogenase reductase Sdr
FDP16_RS03625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FDP16_RS03640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDP16_RS03650	COG0488	(ABC) transporter
FDP16_RS03665	COG0494	nUDIX hydrolase
FDP16_RS03670	COG1983	PspC domain protein
FDP16_RS03680	COG0346	lactoylglutathione lyase activity
FDP16_RS03690	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FDP16_RS03695	COG0081	regulation of translation
FDP16_RS03700	COG0531	amino acid
FDP16_RS03705	COG0528	UMP kinase activity
FDP16_RS03710	COG0233	cytoplasmic translational termination
FDP16_RS03715	COG2996	Protein conserved in bacteria
FDP16_RS03720	COG4479	Belongs to the UPF0346 family
FDP16_RS03725	COG1702	phosphate starvation-inducible protein PhoH
FDP16_RS03735	COG0686	Belongs to the AlaDH PNT family
FDP16_RS03740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDP16_RS03750	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FDP16_RS03755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FDP16_RS03760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDP16_RS03765	COG3177	Filamentation induced by cAMP protein fic
FDP16_RS03780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FDP16_RS03785	COG0237	dephospho-CoA kinase activity
FDP16_RS03790	COG2814	Major facilitator Superfamily
FDP16_RS03795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FDP16_RS03805	COG0557	exoribonuclease II activity
FDP16_RS03810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FDP16_RS03825	COG3615	Tellurite resistance protein tehB
FDP16_RS03825	COG0500	methyltransferase
FDP16_RS03850	COG1136	(ABC) transporter
FDP16_RS03850	COG0577	efflux transmembrane transporter activity
FDP16_RS03865	COG1959	2 iron, 2 sulfur cluster binding
FDP16_RS03870	COG2514	catechol 2,3-dioxygenase activity
FDP16_RS03875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDP16_RS03890	COG1120	ATPase activity
FDP16_RS03900	COG0006	proline dipeptidase activity
FDP16_RS03905	COG1609	Transcriptional regulator
FDP16_RS03915	COG0438	transferase activity, transferring glycosyl groups
FDP16_RS03930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FDP16_RS03950	COG0765	amino acid transport
FDP16_RS03955	COG0765	amino acid transport
FDP16_RS03960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP16_RS03965	COG1126	abc transporter atp-binding protein
FDP16_RS03970	COG0745	RESPONSE REGULATOR receiver
FDP16_RS03975	COG5002	protein histidine kinase activity
FDP16_RS03980	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FDP16_RS03985	COG2832	Protein of unknown function (DUF454)
FDP16_RS03990	COG0571	ribonuclease III activity
FDP16_RS03995	COG1196	nuclear chromosome segregation
FDP16_RS04000	COG0561	phosphatase activity
FDP16_RS04005	COG0561	phosphatase activity
FDP16_RS04010	COG0552	protein localization to endoplasmic reticulum
FDP16_RS04015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FDP16_RS04020	COG3689	TIGRFAM TIGR03943 family protein
FDP16_RS04025	COG0701	Predicted permease
FDP16_RS04035	COG2183	response to ionizing radiation
FDP16_RS04040	COG3091	SprT-like family
FDP16_RS04050	COG1051	belongs to the nudix hydrolase family
FDP16_RS04055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FDP16_RS04060	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FDP16_RS04100	COG4443	Transcriptional Coactivator p15 (PC4)
FDP16_RS04105	COG1268	BioY protein
FDP16_RS04115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDP16_RS04120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP16_RS04125	COG1136	(ABC) transporter
FDP16_RS04130	COG0577	efflux transmembrane transporter activity
FDP16_RS04135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FDP16_RS04145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDP16_RS04165	COG0772	Belongs to the SEDS family
FDP16_RS04170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FDP16_RS04175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FDP16_RS04190	COG1442	glycosyl transferase family 8
FDP16_RS04195	COG1216	Glycosyl transferase, family 2
FDP16_RS04230	COG1215	transferase activity, transferring glycosyl groups
FDP16_RS04250	COG1368	sulfuric ester hydrolase activity
FDP16_RS04270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FDP16_RS04280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FDP16_RS04285	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FDP16_RS04295	COG2131	deaminase
FDP16_RS04305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FDP16_RS04310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDP16_RS04325	COG0024	Methionine aminopeptidase
FDP16_RS04340	COG1846	Transcriptional regulator
FDP16_RS04350	COG2246	polysaccharide biosynthetic process
FDP16_RS04355	COG4708	membrane
FDP16_RS04360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FDP16_RS04365	COG1597	lipid kinase activity
FDP16_RS04370	COG1523	belongs to the glycosyl hydrolase 13 family
FDP16_RS04375	COG1368	sulfuric ester hydrolase activity
FDP16_RS04395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FDP16_RS04400	COG0710	3-dehydroquinate dehydratase activity
FDP16_RS04405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FDP16_RS04410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FDP16_RS04420	COG0287	Prephenate dehydrogenase
FDP16_RS04425	COG3679	Belongs to the UPF0342 family
FDP16_RS04430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FDP16_RS04440	COG0077	Prephenate dehydratase
FDP16_RS04450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FDP16_RS04455	COG1396	sequence-specific DNA binding
FDP16_RS04460	COG0602	queuosine metabolic process
FDP16_RS04490	COG1132	(ABC) transporter
FDP16_RS04500	COG0510	thiamine kinase activity
FDP16_RS04505	COG0366	Alpha amylase catalytic
FDP16_RS04530	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FDP16_RS04535	COG1074	ATP-dependent DNA helicase activity
FDP16_RS04545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FDP16_RS04550	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FDP16_RS04555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDP16_RS04560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FDP16_RS04565	COG0131	Imidazoleglycerol-phosphate dehydratase
FDP16_RS04570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FDP16_RS04575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FDP16_RS04580	COG0107	imidazoleglycerol-phosphate synthase activity
FDP16_RS04585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDP16_RS04590	COG0140	phosphoribosyl-ATP diphosphatase activity
FDP16_RS04630	COG2274	protein secretion by the type I secretion system
FDP16_RS04680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FDP16_RS04695	COG1234	tRNA 3'-trailer cleavage
FDP16_RS04700	COG0300	oxidoreductase activity
FDP16_RS04720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FDP16_RS04720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDP16_RS04730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FDP16_RS04735	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FDP16_RS04745	COG0625	glutathione transferase activity
FDP16_RS04750	COG2384	SAM-dependent methyltransferase
FDP16_RS04755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDP16_RS04760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDP16_RS04765	COG1051	belongs to the nudix hydrolase family
FDP16_RS04775	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FDP16_RS04785	COG1088	dTDP-glucose 4,6-dehydratase activity
FDP16_RS04795	COG1247	-acetyltransferase
FDP16_RS04800	COG3142	Participates in the control of copper homeostasis
FDP16_RS04805	COG2315	Protein conserved in bacteria
FDP16_RS04810	COG1132	(ABC) transporter
FDP16_RS04815	COG1132	(ABC) transporter
FDP16_RS04820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDP16_RS04835	COG1272	protein, Hemolysin III
FDP16_RS04850	COG3022	response to hydroperoxide
FDP16_RS04900	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDP16_RS04905	COG1846	Transcriptional regulator
FDP16_RS04915	COG0436	Aminotransferase
FDP16_RS04945	COG0017	Asparaginyl-tRNA synthetase
FDP16_RS04960	COG1132	(ABC) transporter
FDP16_RS04965	COG0488	(ABC) transporter
FDP16_RS05000	COG0556	nucleotide-excision repair
FDP16_RS05020	COG1051	belongs to the nudix hydrolase family
FDP16_RS05030	COG1827	regulation of RNA biosynthetic process
FDP16_RS05040	COG2824	Alkylphosphonate utilization operon protein PhnA
FDP16_RS05055	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FDP16_RS05065	COG0540	Belongs to the ATCase OTCase family
FDP16_RS05070	COG0505	Belongs to the CarA family
FDP16_RS05075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FDP16_RS05080	COG0803	Belongs to the bacterial solute-binding protein 9 family
FDP16_RS05095	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDP16_RS05100	COG4221	oxidoreductase activity
FDP16_RS05130	COG0561	phosphatase activity
FDP16_RS05135	COG0481	GTPase activity
FDP16_RS05160	COG2207	Transcriptional regulator
FDP16_RS05160	COG3708	Transcriptional regulator
FDP16_RS05180	COG1011	Hydrolase
FDP16_RS05185	COG0228	four-way junction DNA binding
FDP16_RS05190	COG1837	Belongs to the UPF0109 family
FDP16_RS05200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDP16_RS05205	COG0569	domain protein
FDP16_RS05230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDP16_RS05235	COG0336	Belongs to the RNA methyltransferase TrmD family
FDP16_RS05245	COG3833	ABC-type maltose transport systems, permease component
FDP16_RS05250	COG1175	transmembrane transport
FDP16_RS05260	COG0322	excinuclease ABC activity
FDP16_RS05290	COG1573	uracil-dna glycosylase
FDP16_RS05300	COG1063	alcohol dehydrogenase
FDP16_RS05310	COG1876	peptidase activity
FDP16_RS05350	COG5444	nuclease activity
FDP16_RS05385	COG5444	nuclease activity
FDP16_RS05440	COG0254	rRNA binding
FDP16_RS05445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FDP16_RS05450	COG0716	FMN binding
FDP16_RS05465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FDP16_RS05470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FDP16_RS05475	COG0335	large ribosomal subunit rRNA binding
FDP16_RS05485	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FDP16_RS05490	COG1518	maintenance of DNA repeat elements
FDP16_RS05495	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FDP16_RS05505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FDP16_RS05510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FDP16_RS05515	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FDP16_RS05520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FDP16_RS05525	COG0813	purine-nucleoside phosphorylase activity
FDP16_RS05550	COG0543	2 iron, 2 sulfur cluster binding
FDP16_RS05555	COG0167	dihydroorotate dehydrogenase activity
FDP16_RS05560	COG0284	orotidine-5'-phosphate decarboxylase activity
FDP16_RS05565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FDP16_RS05580	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FDP16_RS05585	COG1051	belongs to the nudix hydrolase family
FDP16_RS05595	COG0737	Belongs to the 5'-nucleotidase family
FDP16_RS05600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FDP16_RS05605	COG0187	DNA topoisomerase II activity
FDP16_RS05620	COG0456	acetyltransferase
FDP16_RS05620	COG1214	PFAM Peptidase M22, glycoprotease
FDP16_RS05625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDP16_RS05635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FDP16_RS05640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDP16_RS05660	COG0539	negative regulation of cytoplasmic translation
FDP16_RS05675	COG0039	L-malate dehydrogenase activity
FDP16_RS05680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FDP16_RS05685	COG3764	Sortase (surface protein transpeptidase)
FDP16_RS05700	COG2003	Belongs to the UPF0758 family
FDP16_RS05705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FDP16_RS05725	COG1104	cysteine desulfurase activity
FDP16_RS05730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDP16_RS05740	COG2357	RelA SpoT domain protein
FDP16_RS05750	COG0564	pseudouridine synthase activity
FDP16_RS05755	COG0280	phosphate acetyltransferase
FDP16_RS05760	COG1194	a g-specific adenine glycosylase
FDP16_RS05775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDP16_RS05780	COG4684	Psort location CytoplasmicMembrane, score
FDP16_RS05785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FDP16_RS05795	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FDP16_RS05800	COG1247	-acetyltransferase
FDP16_RS05820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FDP16_RS05825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDP16_RS05840	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FDP16_RS05850	COG1940	carbohydrate kinase activity
FDP16_RS05860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FDP16_RS05865	COG3711	transcriptional antiterminator
FDP16_RS05870	COG0110	maltose O-acetyltransferase activity
FDP16_RS05875	COG0758	DNA mediated transformation
FDP16_RS05880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDP16_RS05910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FDP16_RS05915	COG0022	dehydrogenase e1 component
FDP16_RS05920	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDP16_RS05925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDP16_RS05930	COG0095	Lipoate-protein ligase
FDP16_RS05940	COG4974	Belongs to the 'phage' integrase family
FDP16_RS05955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDP16_RS05970	COG2188	Transcriptional regulator
FDP16_RS05990	COG0741	lytic transglycosylase activity
FDP16_RS06000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FDP16_RS06005	COG0009	L-threonylcarbamoyladenylate synthase
FDP16_RS06010	COG2890	protein-(glutamine-N5) methyltransferase activity
FDP16_RS06015	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FDP16_RS06020	COG1435	thymidine kinase activity
FDP16_RS06025	COG1942	4-Oxalocrotonate Tautomerase
FDP16_RS06030	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDP16_RS06035	COG0022	dehydrogenase e1 component
FDP16_RS06040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FDP16_RS06050	COG0542	response to heat
FDP16_RS06055	COG0534	Mate efflux family protein
FDP16_RS06060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FDP16_RS06065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FDP16_RS06070	COG0805	protein transport
FDP16_RS06075	COG0672	)-iron permease
FDP16_RS06080	COG2837	iron assimilation
FDP16_RS06085	COG2822	iron ion transport
FDP16_RS06090	COG0038	chloride channel
FDP16_RS06110	COG3976	FMN-binding domain protein
FDP16_RS06110	COG0431	NADPH-dependent FMN reductase
FDP16_RS06110	COG1053	succinate dehydrogenase
FDP16_RS06120	COG0785	Cytochrome C biogenesis protein
FDP16_RS06125	COG2972	Histidine kinase
FDP16_RS06130	COG2207	Transcriptional regulator
FDP16_RS06130	COG4753	response regulator
FDP16_RS06135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDP16_RS06135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDP16_RS06140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FDP16_RS06150	COG0785	Cytochrome C biogenesis protein
FDP16_RS06155	COG5002	protein histidine kinase activity
FDP16_RS06160	COG0745	RESPONSE REGULATOR receiver
FDP16_RS06170	COG1114	Component of the transport system for branched-chain amino acids
FDP16_RS06205	COG0222	ribosome binding
FDP16_RS06210	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FDP16_RS06215	COG2116	formate transmembrane transporter activity
FDP16_RS06220	COG2040	homocysteine
FDP16_RS06225	COG0833	amino acid
FDP16_RS06230	COG1388	LysM domain
FDP16_RS06230	COG1705	Flagellar rod assembly protein muramidase FlgJ
FDP16_RS06235	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FDP16_RS06240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FDP16_RS06245	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FDP16_RS06250	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FDP16_RS06255	COG1940	carbohydrate kinase activity
FDP16_RS06265	COG0488	(ABC) transporter
FDP16_RS06270	COG0617	tRNA 3'-terminal CCA addition
FDP16_RS06275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FDP16_RS06280	COG1307	EDD domain protein, DegV family
FDP16_RS06290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP16_RS06290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP16_RS06290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP16_RS06295	COG1105	Belongs to the carbohydrate kinase PfkB family
FDP16_RS06300	COG1349	DNA-binding transcription factor activity
FDP16_RS06305	COG1266	CAAX protease self-immunity
FDP16_RS06315	COG0647	UMP catabolic process
FDP16_RS06325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FDP16_RS06335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FDP16_RS06340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FDP16_RS06345	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FDP16_RS06360	COG0564	pseudouridine synthase activity
FDP16_RS06370	COG0583	DNA-binding transcription factor activity
FDP16_RS06375	COG0456	acetyltransferase
FDP16_RS06380	COG4166	transmembrane transport
FDP16_RS06385	COG1472	Belongs to the glycosyl hydrolase 3 family
FDP16_RS06395	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FDP16_RS06405	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FDP16_RS06415	COG0301	tRNA thio-modification
FDP16_RS06420	COG1104	cysteine desulfurase activity
FDP16_RS06455	COG1177	transmembrane transport
FDP16_RS06460	COG1175	transmembrane transport
FDP16_RS06465	COG3842	ATPase activity
FDP16_RS06470	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FDP16_RS06475	COG0083	homoserine kinase activity
FDP16_RS06505	COG1744	ABC transporter substrate-binding protein PnrA-like
FDP16_RS06510	COG0295	cytidine deaminase activity
FDP16_RS06515	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FDP16_RS06520	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FDP16_RS06525	COG2813	Specifically methylates the guanine in position
FDP16_RS06530	COG1072	(Pantothenic acid kinase))
FDP16_RS06535	COG0268	Binds directly to 16S ribosomal RNA
FDP16_RS06630	COG1131	(ABC) transporter
FDP16_RS06640	COG1363	Peptidase, m42
FDP16_RS06665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDP16_RS06675	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FDP16_RS06680	COG3842	ATPase activity
FDP16_RS06685	COG0366	Alpha amylase catalytic
FDP16_RS06690	COG0395	ABC-type sugar transport system, permease component
FDP16_RS06695	COG1175	transmembrane transport
FDP16_RS06700	COG1653	transport
FDP16_RS06705	COG3345	alpha-galactosidase
FDP16_RS06710	COG2207	Transcriptional regulator
FDP16_RS06715	COG1609	Transcriptional regulator
FDP16_RS06730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FDP16_RS06735	COG1956	GAF domain-containing protein
FDP16_RS06785	COG1174	glycine betaine transport
FDP16_RS06810	COG0066	3-isopropylmalate dehydratase activity
FDP16_RS06815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FDP16_RS06865	COG0572	uridine kinase
FDP16_RS06870	COG0673	inositol 2-dehydrogenase activity
FDP16_RS06880	COG0726	polysaccharide deacetylase
FDP16_RS06895	COG5002	protein histidine kinase activity
FDP16_RS06900	COG0745	RESPONSE REGULATOR receiver
FDP16_RS06940	COG0704	Plays a role in the regulation of phosphate uptake
FDP16_RS06945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDP16_RS06950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDP16_RS06955	COG0581	inorganic phosphate transmembrane transporter activity
FDP16_RS06960	COG0573	inorganic phosphate transmembrane transporter activity
FDP16_RS06970	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FDP16_RS06970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FDP16_RS06975	COG0483	inositol monophosphate 1-phosphatase activity
FDP16_RS06985	COG1393	Belongs to the ArsC family
FDP16_RS06990	COG0196	riboflavin kinase activity
FDP16_RS06995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDP16_RS07030	COG1132	(ABC) transporter
FDP16_RS07050	COG1136	(ABC) transporter
FDP16_RS07055	COG0577	efflux transmembrane transporter activity
FDP16_RS07070	COG1063	alcohol dehydrogenase
FDP16_RS07095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDP16_RS07095	COG0072	phenylalanine-tRNA ligase activity
FDP16_RS07115	COG1131	(ABC) transporter
FDP16_RS07130	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FDP16_RS07145	COG3527	Alpha-acetolactate decarboxylase
FDP16_RS07155	COG0628	permease
FDP16_RS07160	COG3850	Histidine kinase
FDP16_RS07160	COG5002	protein histidine kinase activity
FDP16_RS07170	COG0577	efflux transmembrane transporter activity
FDP16_RS07175	COG1136	(ABC) transporter
FDP16_RS07190	COG2706	6-phosphogluconolactonase activity
FDP16_RS07200	COG2239	Acts as a magnesium transporter
FDP16_RS07210	COG0148	phosphopyruvate hydratase activity
FDP16_RS07230	COG0560	Phosphoserine phosphatase
FDP16_RS07235	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FDP16_RS07250	COG0693	protein deglycase activity
FDP16_RS07255	COG0772	Belongs to the SEDS family
FDP16_RS07265	COG1199	ATP-dependent helicase activity
FDP16_RS07265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDP16_RS07290	COG2884	Cell division ATP-binding protein ftsE
FDP16_RS07320	COG1078	dGTPase activity
FDP16_RS07330	COG2348	transferase activity, transferring amino-acyl groups
FDP16_RS07355	COG0149	triose-phosphate isomerase activity
FDP16_RS07360	COG1091	dTDP-4-dehydrorhamnose reductase activity
FDP16_RS07370	COG0463	Glycosyl transferase, family 2
FDP16_RS07375	COG2873	o-acetylhomoserine
FDP16_RS07390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FDP16_RS07425	COG0469	pyruvate kinase activity
FDP16_RS07430	COG0205	6-phosphofructokinase activity
FDP16_RS07440	COG1131	(ABC) transporter
FDP16_RS07450	COG1346	cytolysis
FDP16_RS07480	COG0653	protein targeting
FDP16_RS07500	COG0201	protein transport
FDP16_RS07535	COG2151	metal-sulfur cluster biosynthetic enzyme
FDP16_RS07540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FDP16_RS07545	COG0358	DNA primase activity
FDP16_RS07550	COG1970	mechanosensitive ion channel activity
FDP16_RS07555	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FDP16_RS07580	COG3759	membrane
FDP16_RS07585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDP16_RS07590	COG0492	ferredoxin-NADP+ reductase activity
FDP16_RS07595	COG1481	regulation of sporulation
FDP16_RS07600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FDP16_RS07605	COG1660	Displays ATPase and GTPase activities
FDP16_RS07610	COG0251	oxidation-reduction process
FDP16_RS07620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FDP16_RS07635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDP16_RS07645	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FDP16_RS07650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDP16_RS07655	COG3442	glutamine amidotransferase
FDP16_RS07710	COG0488	(ABC) transporter
FDP16_RS07735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDP16_RS07750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FDP16_RS07755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FDP16_RS07760	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FDP16_RS07765	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FDP16_RS07770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FDP16_RS07775	COG0356	it plays a direct role in the translocation of protons across the membrane
FDP16_RS07785	COG1482	cell wall glycoprotein biosynthetic process
FDP16_RS07790	COG2188	Transcriptional regulator
FDP16_RS07795	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FDP16_RS07810	COG2723	6-phospho-beta-galactosidase activity
FDP16_RS07815	COG1940	carbohydrate kinase activity
FDP16_RS07825	COG0058	SHG alpha-glucan phosphorylase activity
FDP16_RS07830	COG0297	glycogen (starch) synthase activity
FDP16_RS07835	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FDP16_RS07840	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FDP16_RS07845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FDP16_RS07850	COG1012	belongs to the aldehyde dehydrogenase family
FDP16_RS07860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP16_RS07865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDP16_RS07880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDP16_RS07905	COG1597	lipid kinase activity
FDP16_RS07930	COG1476	TRANSCRIPTIONal
FDP16_RS07940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDP16_RS07945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FDP16_RS07950	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FDP16_RS07955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FDP16_RS07960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FDP16_RS07970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDP16_RS07975	COG4122	O-methyltransferase activity
FDP16_RS07990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FDP16_RS08000	COG1447	Phosphotransferase system cellobiose-specific component IIA
FDP16_RS08005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP16_RS08005	COG3711	transcriptional antiterminator
FDP16_RS08015	COG4095	Psort location CytoplasmicMembrane, score
FDP16_RS08020	COG2723	6-phospho-beta-galactosidase activity
FDP16_RS08040	COG0363	glucosamine-6-phosphate deaminase activity
FDP16_RS08050	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FDP16_RS08055	COG1438	arginine binding
FDP16_RS08060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FDP16_RS08065	COG1288	antiporter activity
FDP16_RS08070	COG0549	Belongs to the carbamate kinase family
FDP16_RS08075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FDP16_RS08080	COG2235	arginine
FDP16_RS08100	COG4377	Putative membrane peptidase family (DUF2324)
FDP16_RS08115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FDP16_RS08120	COG1466	dna polymerase III delta subunit
FDP16_RS08130	COG2333	competence protein COMEC
FDP16_RS08130	COG0658	competence protein
FDP16_RS08135	COG1596	polysaccharide export
FDP16_RS08135	COG1555	photosystem II stabilization
FDP16_RS08145	COG0204	Acyl-transferase
FDP16_RS08150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FDP16_RS08155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FDP16_RS08160	COG2827	Endonuclease containing a URI domain
FDP16_RS08170	COG1755	Isoprenylcysteine carboxyl methyltransferase
FDP16_RS08175	COG1349	DNA-binding transcription factor activity
FDP16_RS08180	COG3775	system Galactitol-specific IIC component
FDP16_RS08200	COG0513	Belongs to the DEAD box helicase family
FDP16_RS08210	COG0538	isocitrate dehydrogenase activity
FDP16_RS08215	COG0372	Belongs to the citrate synthase family
FDP16_RS08220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FDP16_RS08230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDP16_RS08255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDP16_RS08260	COG1181	Belongs to the D-alanine--D-alanine ligase family
FDP16_RS08265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDP16_RS08270	COG0768	penicillin binding
FDP16_RS08275	COG0588	phosphoglycerate mutase activity
FDP16_RS08295	COG0735	belongs to the Fur family
FDP16_RS08305	COG1307	EDD domain protein, DegV family
FDP16_RS08315	COG2801	Transposase and inactivated derivatives
FDP16_RS08330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDP16_RS08335	COG0497	DNA recombination
FDP16_RS08345	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FDP16_RS08355	COG1722	exodeoxyribonuclease VII activity
FDP16_RS08365	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FDP16_RS08375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FDP16_RS08380	COG4703	Protein of unknown function (DUF1797)
FDP16_RS08385	COG0542	response to heat
FDP16_RS08395	COG2378	regulation of single-species biofilm formation
FDP16_RS08425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDP16_RS08430	COG3599	regulation of cell shape
FDP16_RS08445	COG1799	cell septum assembly
FDP16_RS08450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FDP16_RS08455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FDP16_RS08465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FDP16_RS08470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FDP16_RS08475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FDP16_RS08490	COG1187	pseudouridine synthase activity
FDP16_RS08530	COG0159	tryptophan synthase activity
FDP16_RS08540	COG0135	phosphoribosylanthranilate isomerase activity
FDP16_RS08545	COG0134	indole-3-glycerol-phosphate synthase activity
FDP16_RS08550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FDP16_RS08555	COG0512	Glutamine amidotransferase of anthranilate synthase
FDP16_RS08560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDP16_RS08565	COG0133	tryptophan synthase activity
FDP16_RS08575	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FDP16_RS08580	COG4470	Protein conserved in bacteria
FDP16_RS08585	COG3480	Lon protease (S16) C-terminal proteolytic domain
FDP16_RS08590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FDP16_RS08595	COG0742	ribosomal rna small subunit methyltransferase
FDP16_RS08610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDP16_RS08630	COG1396	sequence-specific DNA binding
FDP16_RS08645	COG1396	sequence-specific DNA binding
FDP16_RS08650	COG0501	Belongs to the peptidase M48B family
FDP16_RS08655	COG1704	LemA family
FDP16_RS08660	COG1309	transcriptional regulator
FDP16_RS08665	COG2814	Major facilitator Superfamily
FDP16_RS08675	COG0577	efflux transmembrane transporter activity
FDP16_RS08675	COG1136	(ABC) transporter
FDP16_RS08680	COG0357	Ribosomal RNA small subunit methyltransferase G
FDP16_RS08695	COG1122	ATPase activity
FDP16_RS08765	COG4720	Psort location CytoplasmicMembrane, score
FDP16_RS08770	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
FDP16_RS08790	COG1473	amidohydrolase
FDP16_RS08800	COG0217	transcriptional regulatory protein
FDP16_RS08815	COG1323	Belongs to the UPF0348 family
FDP16_RS08820	COG2226	methyltransferase
FDP16_RS08825	COG0799	negative regulation of ribosome biogenesis
FDP16_RS08830	COG1335	isochorismatase
FDP16_RS08835	COG1713	HD superfamily hydrolase involved in NAD metabolism
FDP16_RS08840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FDP16_RS08845	COG1534	Rna-binding protein
FDP16_RS08850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FDP16_RS08855	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FDP16_RS08870	COG1063	alcohol dehydrogenase
FDP16_RS08900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDP16_RS08905	COG0154	amidase activity
FDP16_RS08910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDP16_RS08915	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FDP16_RS08920	COG1335	isochorismatase
FDP16_RS08925	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FDP16_RS08935	COG0436	Aminotransferase
FDP16_RS08945	COG0561	phosphatase activity
FDP16_RS08950	COG0252	asparaginase activity
FDP16_RS08960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FDP16_RS08965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDP16_RS08970	COG0736	holo-[acyl-carrier-protein] synthase activity
FDP16_RS08975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDP16_RS08980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDP16_RS08985	COG0653	protein targeting
FDP16_RS09020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FDP16_RS09040	COG1846	Transcriptional regulator
FDP16_RS09045	COG0242	peptide deformylase activity
FDP16_RS09050	COG1940	carbohydrate kinase activity
FDP16_RS09055	COG2190	(PTS) system
FDP16_RS09055	COG1263	PTS System
FDP16_RS09055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP16_RS09060	COG1621	beta-fructofuranosidase activity
FDP16_RS09065	COG1609	Transcriptional regulator
FDP16_RS09070	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FDP16_RS09075	COG1523	belongs to the glycosyl hydrolase 13 family
FDP16_RS09090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FDP16_RS09095	COG0006	proline dipeptidase activity
FDP16_RS09100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FDP16_RS09115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FDP16_RS09120	COG0629	single-stranded DNA binding
FDP16_RS09125	COG0360	Binds together with S18 to 16S ribosomal RNA
FDP16_RS09130	COG1228	amidohydrolase
FDP16_RS09135	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FDP16_RS09145	COG3404	Formiminotransferase-cyclodeaminase
FDP16_RS09150	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FDP16_RS09160	COG0531	amino acid
FDP16_RS09165	COG2986	histidine ammonia-lyase
FDP16_RS09170	COG0010	Belongs to the arginase family
FDP16_RS09200	COG0406	alpha-ribazole phosphatase activity
FDP16_RS09220	COG2207	Transcriptional regulator
FDP16_RS09230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FDP16_RS09240	COG0628	permease
FDP16_RS09255	COG0596	Alpha beta hydrolase
FDP16_RS09260	COG1131	(ABC) transporter
FDP16_RS09270	COG2205	protein histidine kinase activity
FDP16_RS09280	COG2723	6-phospho-beta-galactosidase activity
FDP16_RS09290	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FDP16_RS09300	COG0028	Belongs to the TPP enzyme family
FDP16_RS09305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FDP16_RS09310	COG0561	phosphatase activity
FDP16_RS09315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FDP16_RS09325	COG3448	diguanylate cyclase activity
FDP16_RS09325	COG4175	Glycine betaine
FDP16_RS09360	COG0402	S-adenosylhomocysteine deaminase activity
FDP16_RS09380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDP16_RS09380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDP16_RS09385	COG0167	dihydroorotate dehydrogenase activity
FDP16_RS09390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDP16_RS09410	COG5504	Zn-dependent protease
FDP16_RS09420	COG0668	transmembrane transport
FDP16_RS09425	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FDP16_RS09430	COG1115	amino acid carrier protein
FDP16_RS09435	COG3118	belongs to the thioredoxin family
FDP16_RS09450	COG1193	negative regulation of DNA recombination
FDP16_RS09470	COG0681	Belongs to the peptidase S26 family
FDP16_RS09475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDP16_RS09480	COG1309	transcriptional regulator
FDP16_RS09500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDP16_RS09505	COG1882	Formate acetyltransferase
FDP16_RS09520	COG3425	synthase
FDP16_RS09530	COG1304	FMN binding
FDP16_RS09565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FDP16_RS09570	COG2936	dipeptidyl-peptidase activity
FDP16_RS09575	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FDP16_RS09580	COG0584	glycerophosphoryl diester phosphodiesterase
FDP16_RS09590	COG2081	HI0933 family
FDP16_RS09605	COG0789	Transcriptional regulator
FDP16_RS09610	COG2226	methyltransferase
FDP16_RS09625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FDP16_RS09635	COG1214	PFAM Peptidase M22, glycoprotease
FDP16_RS09680	COG0174	glutamine synthetase
FDP16_RS09685	COG0789	Transcriptional regulator
FDP16_RS09695	COG3942	CHAP domain
FDP16_RS09705	COG0126	phosphoglycerate kinase activity
FDP16_RS09715	COG0495	leucyl-tRNA aminoacylation
FDP16_RS09730	COG1442	glycosyl transferase family 8
FDP16_RS09730	COG1216	Glycosyl transferase, family 2
FDP16_RS09755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP16_RS09755	COG1263	PTS System
FDP16_RS09755	COG2190	(PTS) system
FDP16_RS09810	COG4989	oxidoreductase activity
FDP16_RS09820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FDP16_RS09825	COG1447	Phosphotransferase system cellobiose-specific component IIA
FDP16_RS09830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FDP16_RS09835	COG1940	carbohydrate kinase activity
FDP16_RS09850	COG3590	peptidase
FDP16_RS09895	COG1846	Transcriptional regulator
FDP16_RS09900	COG1673	EVE domain
FDP16_RS09915	COG1490	D-aminoacyl-tRNA deacylase activity
FDP16_RS09925	COG1511	domain protein
FDP16_RS09925	COG1511	domain protein
FDP16_RS09935	COG4499	WXG100 protein secretion system (Wss), protein YukC
FDP16_RS10060	COG4842	Belongs to the WXG100 family
FDP16_RS10065	COG0737	Belongs to the 5'-nucleotidase family
FDP16_RS10070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDP16_RS10085	COG1051	belongs to the nudix hydrolase family
FDP16_RS10095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDP16_RS10120	COG0459	protein refolding
FDP16_RS10135	COG3716	PTS system mannose fructose sorbose family IID component
FDP16_RS10140	COG3715	PTS system
FDP16_RS10160	COG2197	response regulator
FDP16_RS10165	COG4585	Histidine kinase
FDP16_RS10190	COG1846	Transcriptional regulator
FDP16_RS10210	COG1363	Peptidase, m42
FDP16_RS10265	COG1131	(ABC) transporter
FDP16_RS10270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDP16_RS10270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FDP16_RS10275	COG0302	gtp cyclohydrolase
FDP16_RS10280	COG0285	dihydrofolate synthase activity
FDP16_RS10285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDP16_RS10300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDP16_RS10330	COG4537	Required for transformation and DNA binding
FDP16_RS10335	COG1459	type II secretion system
FDP16_RS10340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDP16_RS10350	COG1063	alcohol dehydrogenase
FDP16_RS10355	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FDP16_RS10360	COG1215	transferase activity, transferring glycosyl groups
FDP16_RS10370	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FDP16_RS10380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FDP16_RS10385	COG0085	RNA polymerase activity
FDP16_RS10405	COG0500	methyltransferase
FDP16_RS10410	COG3842	ATPase activity
FDP16_RS10440	COG2217	Heavy metal translocating P-type atpase
FDP16_RS10450	COG0803	Belongs to the bacterial solute-binding protein 9 family
FDP16_RS10450	COG3443	Belongs to the bacterial solute-binding protein 9 family
FDP16_RS10455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDP16_RS10460	COG1121	(ABC) transporter
FDP16_RS10465	COG1846	Transcriptional regulator
FDP16_RS10545	COG1674	ftsk spoiiie
FDP16_RS10600	COG0433	COG0433 Predicted ATPase
FDP16_RS10610	COG3942	CHAP domain
FDP16_RS10610	COG1705	Flagellar rod assembly protein muramidase FlgJ
FDP16_RS10635	COG0582	viral genome integration into host DNA
FDP16_RS10725	COG0203	ribosomal protein L17
FDP16_RS10730	COG0202	RNA polymerase activity
FDP16_RS10735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FDP16_RS10740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FDP16_RS10745	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FDP16_RS10750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FDP16_RS10760	COG0201	protein transport
FDP16_RS10765	COG0200	Binds to the 23S rRNA
FDP16_RS10770	COG1841	ribosomal large subunit assembly
FDP16_RS10775	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FDP16_RS10780	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FDP16_RS10785	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FDP16_RS10790	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FDP16_RS10795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FDP16_RS10800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FDP16_RS10805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FDP16_RS10810	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FDP16_RS10815	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FDP16_RS10820	COG0255	Belongs to the universal ribosomal protein uL29 family
FDP16_RS10825	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FDP16_RS10830	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FDP16_RS10835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FDP16_RS10840	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FDP16_RS10845	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FDP16_RS10850	COG0089	rRNA binding
FDP16_RS10855	COG0088	Forms part of the polypeptide exit tunnel
FDP16_RS10860	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FDP16_RS10865	COG0051	transcription antitermination factor activity, RNA binding
FDP16_RS10875	COG0343	queuine tRNA-ribosyltransferase activity
FDP16_RS10890	COG1832	CoA-binding protein
FDP16_RS10895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDP16_RS10895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDP16_RS10910	COG0546	phosphoglycolate phosphatase activity
FDP16_RS10920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FDP16_RS10940	COG0124	histidyl-tRNA synthetase
FDP16_RS10945	COG2151	metal-sulfur cluster biosynthetic enzyme
FDP16_RS10950	COG0129	dihydroxy-acid dehydratase activity
FDP16_RS10955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FDP16_RS10960	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FDP16_RS11070	COG1349	DNA-binding transcription factor activity
FDP16_RS11105	COG0582	viral genome integration into host DNA
FDP16_RS11125	COG3480	Lon protease (S16) C-terminal proteolytic domain
FDP16_RS11145	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FDP16_RS11225	COG1230	cation diffusion facilitator family transporter
FDP16_RS11235	COG2807	transmembrane transport
FDP16_RS11240	COG0561	phosphatase activity
FDP16_RS11250	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FDP16_RS11255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDP16_RS11260	COG1696	Membrane protein involved in D-alanine export
FDP16_RS11290	COG1619	proteins homologs of microcin C7 resistance protein MccF
FDP16_RS11305	COG1511	domain protein
FDP16_RS11320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FDP16_RS11330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDP16_RS11335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDP16_RS11340	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FDP16_RS11345	COG1116	anion transmembrane transporter activity
FDP16_RS11355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDP16_RS11455	COG0542	response to heat
FDP16_RS11460	COG0551	DNA topoisomerase type I activity
FDP16_RS11460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDP16_RS11555	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FDP16_RS11565	COG0305	Participates in initiation and elongation during chromosome replication
FDP16_RS11570	COG0359	binds to the 23S rRNA
FDP16_RS11580	COG0445	tRNA wobble uridine modification
FDP16_RS11585	COG0482	sulfurtransferase activity
FDP16_RS11590	COG1760	l-serine dehydratase
FDP16_RS11595	COG1760	l-serine dehydratase
FDP16_RS11610	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FDP16_RS11615	COG1122	ATPase activity
FDP16_RS11620	COG1122	ATPase activity
FDP16_RS11625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FDP16_RS11635	COG0612	Peptidase, M16
FDP16_RS11650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FDP16_RS11655	COG0517	IMP dehydrogenase activity
FDP16_RS11655	COG0516	GMP reductase activity
FDP16_RS11660	COG0180	Tryptophanyl-tRNA synthetase
FDP16_RS11665	COG0488	(ABC) transporter
FDP16_RS11705	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FDP16_RS11710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDP16_RS11715	COG1475	DNA binding