locus-tag	class	description
DK181_RS00010	COG0592	DNA-directed DNA polymerase activity
DK181_RS00020	COG1597	lipid kinase activity
DK181_RS00025	COG0012	GTP binding
DK181_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
DK181_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DK181_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DK181_RS00060	COG0037	tRNA processing
DK181_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DK181_RS00075	COG0531	amino acid
DK181_RS00205	COG3942	CHAP domain
DK181_RS00215	COG0436	Aminotransferase
DK181_RS00220	COG1381	Involved in DNA repair and RecF pathway recombination
DK181_RS00225	COG0416	fatty acid biosynthetic process
DK181_RS00230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK181_RS00240	COG1131	(ABC) transporter
DK181_RS00275	COG1136	(ABC) transporter
DK181_RS00285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DK181_RS00290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DK181_RS00305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DK181_RS00310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DK181_RS00360	COG0151	Belongs to the GarS family
DK181_RS00365	COG1683	Conserved Protein
DK181_RS00375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DK181_RS00400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DK181_RS00405	COG1012	belongs to the aldehyde dehydrogenase family
DK181_RS00500	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DK181_RS00505	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DK181_RS00515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DK181_RS00545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DK181_RS00550	COG0534	Mate efflux family protein
DK181_RS00555	COG1028	Short-chain dehydrogenase reductase Sdr
DK181_RS00565	COG0051	transcription antitermination factor activity, RNA binding
DK181_RS00570	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DK181_RS00585	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DK181_RS00605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DK181_RS00635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DK181_RS00670	COG0201	protein transport
DK181_RS00675	COG0563	adenylate kinase activity
DK181_RS00700	COG0202	RNA polymerase activity
DK181_RS00740	COG1121	(ABC) transporter
DK181_RS00745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK181_RS00755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK181_RS00755	COG4499	WXG100 protein secretion system (Wss), protein YukC
DK181_RS00775	COG4166	transmembrane transport
DK181_RS00785	COG0601	transmembrane transport
DK181_RS00790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK181_RS00795	COG0444	Belongs to the ABC transporter superfamily
DK181_RS00800	COG4608	Belongs to the ABC transporter superfamily
DK181_RS00805	COG2814	Major facilitator Superfamily
DK181_RS00860	COG0583	DNA-binding transcription factor activity
DK181_RS00875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DK181_RS00885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DK181_RS00890	COG1459	type II secretion system
DK181_RS00895	COG4537	Required for transformation and DNA binding
DK181_RS00935	COG0827	DNA restriction-modification system
DK181_RS00945	COG0583	DNA-binding transcription factor activity
DK181_RS00950	COG3830	Belongs to the UPF0237 family
DK181_RS00970	COG0588	phosphoglycerate mutase activity
DK181_RS00975	COG1876	peptidase activity
DK181_RS00980	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK181_RS00985	COG1420	regulation of RNA biosynthetic process
DK181_RS00990	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DK181_RS01000	COG0484	heat shock protein binding
DK181_RS01010	COG0351	phosphomethylpyrimidine kinase
DK181_RS01015	COG4720	Psort location CytoplasmicMembrane, score
DK181_RS01025	COG0668	transmembrane transport
DK181_RS01045	COG0504	CTP synthase activity
DK181_RS01055	COG0191	fructose-bisphosphate aldolase activity
DK181_RS01060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DK181_RS01070	COG1461	Dihydroxyacetone kinase
DK181_RS01075	COG0028	Belongs to the TPP enzyme family
DK181_RS01080	COG0440	acetolactate synthase activity
DK181_RS01085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DK181_RS01125	COG4175	Glycine betaine
DK181_RS01125	COG3448	diguanylate cyclase activity
DK181_RS01140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK181_RS01140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK181_RS01145	COG1832	CoA-binding protein
DK181_RS01150	COG0735	belongs to the Fur family
DK181_RS01155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DK181_RS01165	COG1114	Component of the transport system for branched-chain amino acids
DK181_RS01175	COG0765	amino acid transport
DK181_RS01195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK181_RS01205	COG0719	Fe-S assembly protein
DK181_RS01210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DK181_RS01225	COG3942	CHAP domain
DK181_RS01225	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK181_RS01255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DK181_RS01260	COG3201	nicotinamide mononucleotide transporter
DK181_RS01275	COG0137	argininosuccinate synthase activity
DK181_RS01290	COG0737	Belongs to the 5'-nucleotidase family
DK181_RS01295	COG0594	ribonuclease P activity
DK181_RS01305	COG1847	R3H domain protein
DK181_RS01365	COG1696	Membrane protein involved in D-alanine export
DK181_RS01370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK181_RS01375	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DK181_RS01380	COG4808	Protein conserved in bacteria
DK181_RS01400	COG0657	acetylesterase activity
DK181_RS01400	COG2755	lipolytic protein G-D-S-L family
DK181_RS01410	COG1733	regulation of RNA biosynthetic process
DK181_RS01420	COG0084	hydrolase, TatD family'
DK181_RS01440	COG0693	protein deglycase activity
DK181_RS01515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK181_RS01525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DK181_RS01530	COG0049	tRNA binding
DK181_RS01550	COG0126	phosphoglycerate kinase activity
DK181_RS01570	COG0789	Transcriptional regulator
DK181_RS01575	COG0174	glutamine synthetase
DK181_RS01580	COG3942	CHAP domain
DK181_RS01595	COG1214	PFAM Peptidase M22, glycoprotease
DK181_RS01610	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DK181_RS01620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DK181_RS01630	COG2081	HI0933 family
DK181_RS01655	COG2176	DNA-directed DNA polymerase activity
DK181_RS01660	COG0789	Transcriptional regulator
DK181_RS01670	COG3579	cysteine-type endopeptidase activity
DK181_RS01680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK181_RS01695	COG3599	regulation of cell shape
DK181_RS01705	COG0116	Belongs to the methyltransferase superfamily
DK181_RS01720	COG1854	S-ribosylhomocysteine lyase activity
DK181_RS01730	COG1304	FMN binding
DK181_RS01735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS01760	COG1131	(ABC) transporter
DK181_RS01790	COG0768	penicillin binding
DK181_RS01795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK181_RS01800	COG0513	Belongs to the DEAD box helicase family
DK181_RS01805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS01810	COG0765	amino acid transport
DK181_RS01815	COG1126	abc transporter atp-binding protein
DK181_RS01830	COG1113	amino acid transport
DK181_RS01835	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DK181_RS01870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DK181_RS01885	COG1882	Formate acetyltransferase
DK181_RS01910	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DK181_RS01915	COG0681	Belongs to the peptidase S26 family
DK181_RS01920	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DK181_RS01945	COG0561	phosphatase activity
DK181_RS01995	COG1846	Transcriptional regulator
DK181_RS02000	COG1673	EVE domain
DK181_RS02060	COG2814	Major facilitator Superfamily
DK181_RS02085	COG0006	proline dipeptidase activity
DK181_RS02090	COG2131	deaminase
DK181_RS02115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK181_RS02120	COG1733	regulation of RNA biosynthetic process
DK181_RS02130	COG1609	Transcriptional regulator
DK181_RS02135	COG1621	beta-fructofuranosidase activity
DK181_RS02140	COG1263	PTS System
DK181_RS02140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK181_RS02140	COG2190	(PTS) system
DK181_RS02145	COG1940	carbohydrate kinase activity
DK181_RS02150	COG1482	cell wall glycoprotein biosynthetic process
DK181_RS02155	COG0653	protein targeting
DK181_RS02160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DK181_RS02175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DK181_RS02180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DK181_RS02195	COG0252	asparaginase activity
DK181_RS02200	COG0561	phosphatase activity
DK181_RS02210	COG0436	Aminotransferase
DK181_RS02245	COG1335	isochorismatase
DK181_RS02255	COG1136	(ABC) transporter
DK181_RS02295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK181_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
DK181_RS02330	COG0823	Involved in the tonB-independent uptake of proteins
DK181_RS02330	COG1506	peptidase
DK181_RS02330	COG4946	Tricorn protease homolog
DK181_RS02350	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DK181_RS02355	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK181_RS02365	COG1534	Rna-binding protein
DK181_RS02370	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DK181_RS02375	COG1713	HD superfamily hydrolase involved in NAD metabolism
DK181_RS02385	COG0799	negative regulation of ribosome biogenesis
DK181_RS02390	COG2226	methyltransferase
DK181_RS02420	COG0789	Transcriptional regulator
DK181_RS02445	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DK181_RS02450	COG1461	Dihydroxyacetone kinase
DK181_RS02455	COG2376	Dihydroxyacetone kinase
DK181_RS02460	COG0217	transcriptional regulatory protein
DK181_RS02470	COG0640	Transcriptional regulator
DK181_RS02475	COG0640	Transcriptional regulator
DK181_RS02480	COG0517	IMP dehydrogenase activity
DK181_RS02485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DK181_RS02490	COG0470	DNA polymerase III
DK181_RS02495	COG1774	PSP1 C-terminal conserved region
DK181_RS02500	COG4467	Involved in initiation control of chromosome replication
DK181_RS02510	COG0004	ammonium transporteR
DK181_RS02515	COG0347	Belongs to the P(II) protein family
DK181_RS02520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DK181_RS02525	COG0372	Belongs to the citrate synthase family
DK181_RS02545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DK181_RS02560	COG1393	Belongs to the ArsC family
DK181_RS02565	COG0477	Major facilitator Superfamily
DK181_RS02575	COG3590	peptidase
DK181_RS02585	COG1396	sequence-specific DNA binding
DK181_RS02665	COG0708	Exodeoxyribonuclease III
DK181_RS02675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DK181_RS02680	COG0081	regulation of translation
DK181_RS02695	COG2996	Protein conserved in bacteria
DK181_RS02700	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DK181_RS02700	COG0456	acetyltransferase
DK181_RS02705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS02715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK181_RS02730	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DK181_RS02745	COG1122	ATPase activity
DK181_RS02760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DK181_RS02765	COG0357	Ribosomal RNA small subunit methyltransferase G
DK181_RS02770	COG1704	LemA family
DK181_RS02775	COG0501	Belongs to the peptidase M48B family
DK181_RS02790	COG0745	RESPONSE REGULATOR receiver
DK181_RS02805	COG1484	DNA-dependent DNA replication
DK181_RS02840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DK181_RS02860	COG1242	4 iron, 4 sulfur cluster binding
DK181_RS02865	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DK181_RS02875	COG1119	ATPase activity
DK181_RS02880	COG4535	Mg2 and Co2 transporter CorC
DK181_RS02885	COG1428	Deoxynucleoside kinase
DK181_RS02890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DK181_RS02900	COG1196	nuclear chromosome segregation
DK181_RS02920	COG0772	Belongs to the SEDS family
DK181_RS02925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DK181_RS02930	COG0019	diaminopimelate decarboxylase activity
DK181_RS02935	COG3763	UPF0154 protein
DK181_RS02940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DK181_RS02945	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DK181_RS02950	COG0622	Phosphoesterase
DK181_RS02955	COG0517	IMP dehydrogenase activity
DK181_RS02960	COG0582	viral genome integration into host DNA
DK181_RS02965	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DK181_RS02970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DK181_RS02975	COG1187	pseudouridine synthase activity
DK181_RS02980	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DK181_RS03005	COG1733	regulation of RNA biosynthetic process
DK181_RS03020	COG3328	transposase activity
DK181_RS03045	COG2851	Citrate transporter
DK181_RS03055	COG1131	(ABC) transporter
DK181_RS03065	COG4585	Histidine kinase
DK181_RS03070	COG2197	response regulator
DK181_RS03085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DK181_RS03090	COG0512	Glutamine amidotransferase of anthranilate synthase
DK181_RS03105	COG0135	phosphoribosylanthranilate isomerase activity
DK181_RS03110	COG0133	tryptophan synthase activity
DK181_RS03115	COG0159	tryptophan synthase activity
DK181_RS03135	COG3708	Transcriptional regulator
DK181_RS03135	COG2207	Transcriptional regulator
DK181_RS03140	COG1131	(ABC) transporter
DK181_RS03155	COG4122	O-methyltransferase activity
DK181_RS03160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DK181_RS03175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DK181_RS03195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DK181_RS03200	COG0436	Aminotransferase
DK181_RS03225	COG0513	Belongs to the DEAD box helicase family
DK181_RS03245	COG0281	malic enzyme
DK181_RS03250	COG0583	DNA-binding transcription factor activity
DK181_RS03280	COG0826	peptidase U32
DK181_RS03285	COG4443	Transcriptional Coactivator p15 (PC4)
DK181_RS03300	COG1570	exodeoxyribonuclease VII activity
DK181_RS03315	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DK181_RS03325	COG0497	DNA recombination
DK181_RS03335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DK181_RS03340	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DK181_RS03345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DK181_RS03350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DK181_RS03360	COG1346	cytolysis
DK181_RS03365	COG1380	Effector of murein hydrolase LrgA
DK181_RS03375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DK181_RS03380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DK181_RS03385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS03400	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK181_RS03400	COG3942	CHAP domain
DK181_RS03410	COG0149	triose-phosphate isomerase activity
DK181_RS03440	COG1078	dGTPase activity
DK181_RS03470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DK181_RS03530	COG1199	ATP-dependent helicase activity
DK181_RS03530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DK181_RS03540	COG0436	Aminotransferase
DK181_RS03550	COG0017	Asparaginyl-tRNA synthetase
DK181_RS03555	COG0371	Dehydrogenase
DK181_RS03560	COG0251	oxidation-reduction process
DK181_RS03580	COG1924	4 iron, 4 sulfur cluster binding
DK181_RS03585	COG1309	transcriptional regulator
DK181_RS03610	COG3443	Belongs to the bacterial solute-binding protein 9 family
DK181_RS03610	COG0803	Belongs to the bacterial solute-binding protein 9 family
DK181_RS03615	COG2226	methyltransferase
DK181_RS03635	COG3976	FMN-binding domain protein
DK181_RS03635	COG1053	succinate dehydrogenase
DK181_RS03635	COG0431	NADPH-dependent FMN reductase
DK181_RS03650	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DK181_RS03655	COG0625	glutathione transferase activity
DK181_RS03660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DK181_RS03665	COG0716	FMN binding
DK181_RS03690	COG0077	Prephenate dehydratase
DK181_RS03690	COG1605	Chorismate mutase
DK181_RS03695	COG0038	chloride channel
DK181_RS03700	COG0335	large ribosomal subunit rRNA binding
DK181_RS03720	COG1780	Probably involved in ribonucleotide reductase function
DK181_RS03725	COG2151	metal-sulfur cluster biosynthetic enzyme
DK181_RS03740	COG0772	Belongs to the SEDS family
DK181_RS03745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DK181_RS03750	COG0187	DNA topoisomerase II activity
DK181_RS03755	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DK181_RS03760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DK181_RS03775	COG0300	oxidoreductase activity
DK181_RS03780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DK181_RS03780	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DK181_RS03790	COG4109	DRTGG domain
DK181_RS03795	COG0024	Methionine aminopeptidase
DK181_RS03810	COG1573	uracil-dna glycosylase
DK181_RS03830	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DK181_RS03835	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DK181_RS03850	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DK181_RS03865	COG0813	purine-nucleoside phosphorylase activity
DK181_RS03880	COG1131	(ABC) transporter
DK181_RS03910	COG0583	DNA-binding transcription factor activity
DK181_RS03915	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DK181_RS03925	COG1088	dTDP-glucose 4,6-dehydratase activity
DK181_RS03935	COG0543	2 iron, 2 sulfur cluster binding
DK181_RS03940	COG0167	dihydroorotate dehydrogenase activity
DK181_RS03945	COG0284	orotidine-5'-phosphate decarboxylase activity
DK181_RS03955	COG2315	Protein conserved in bacteria
DK181_RS03960	COG1881	PFAM PEBP family protein
DK181_RS03965	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DK181_RS03975	COG0737	Belongs to the 5'-nucleotidase family
DK181_RS03990	COG0187	DNA topoisomerase II activity
DK181_RS04010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DK181_RS04030	COG0539	negative regulation of cytoplasmic translation
DK181_RS04060	COG1131	(ABC) transporter
DK181_RS04065	COG1725	Transcriptional regulator
DK181_RS04080	COG0469	pyruvate kinase activity
DK181_RS04095	COG2213	PTS system mannitol-specific
DK181_RS04100	COG3711	transcriptional antiterminator
DK181_RS04105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS04110	COG0246	Mannitol dehydrogenase
DK181_RS04145	COG2824	Alkylphosphonate utilization operon protein PhnA
DK181_RS04150	COG0765	amino acid transport
DK181_RS04155	COG1126	abc transporter atp-binding protein
DK181_RS04160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS04165	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DK181_RS04170	COG1115	amino acid carrier protein
DK181_RS04175	COG3842	ATPase activity
DK181_RS04180	COG3833	ABC-type maltose transport systems, permease component
DK181_RS04185	COG1175	transmembrane transport
DK181_RS04195	COG0366	Alpha amylase catalytic
DK181_RS04200	COG1609	Transcriptional regulator
DK181_RS04215	COG2873	o-acetylhomoserine
DK181_RS04230	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DK181_RS04240	COG2384	SAM-dependent methyltransferase
DK181_RS04255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK181_RS04270	COG2706	6-phosphogluconolactonase activity
DK181_RS04275	COG1051	belongs to the nudix hydrolase family
DK181_RS04280	COG0628	permease
DK181_RS04285	COG0457	Tetratricopeptide repeat
DK181_RS04290	COG0028	Belongs to the TPP enzyme family
DK181_RS04295	COG3527	Alpha-acetolactate decarboxylase
DK181_RS04300	COG2246	polysaccharide biosynthetic process
DK181_RS04310	COG4708	membrane
DK181_RS04315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DK181_RS04320	COG1597	lipid kinase activity
DK181_RS04330	COG0356	it plays a direct role in the translocation of protons across the membrane
DK181_RS04370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK181_RS04410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DK181_RS04420	COG5263	repeat protein
DK181_RS04420	COG0366	Alpha amylase catalytic
DK181_RS04430	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DK181_RS04435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DK181_RS04440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DK181_RS04445	COG0560	Phosphoserine phosphatase
DK181_RS04460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DK181_RS04465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DK181_RS04470	COG0107	imidazoleglycerol-phosphate synthase activity
DK181_RS04480	COG0140	phosphoribosyl-ATP diphosphatase activity
DK181_RS04490	COG1368	sulfuric ester hydrolase activity
DK181_RS04495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DK181_RS04505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DK181_RS04520	COG0287	Prephenate dehydrogenase
DK181_RS04525	COG3679	Belongs to the UPF0342 family
DK181_RS04530	COG0513	Belongs to the DEAD box helicase family
DK181_RS04555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DK181_RS04570	COG2226	methyltransferase
DK181_RS04575	COG1956	GAF domain-containing protein
DK181_RS04580	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DK181_RS04595	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DK181_RS04655	COG3177	Filamentation induced by cAMP protein fic
DK181_RS04675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DK181_RS04680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK181_RS04735	COG3290	protein histidine kinase activity
DK181_RS04795	COG1959	2 iron, 2 sulfur cluster binding
DK181_RS04800	COG2514	catechol 2,3-dioxygenase activity
DK181_RS04815	COG1011	Hydrolase
DK181_RS04835	COG1621	beta-fructofuranosidase activity
DK181_RS04835	COG3583	domain protein
DK181_RS04835	COG5492	domain, Protein
DK181_RS04840	COG0322	excinuclease ABC activity
DK181_RS04845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK181_RS04850	COG0285	dihydrofolate synthase activity
DK181_RS04865	COG1104	cysteine desulfurase activity
DK181_RS04885	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DK181_RS04925	COG0583	DNA-binding transcription factor activity
DK181_RS04935	COG0564	pseudouridine synthase activity
DK181_RS04950	COG0540	Belongs to the ATCase OTCase family
DK181_RS04955	COG0505	Belongs to the CarA family
DK181_RS04985	COG0346	lactoylglutathione lyase activity
DK181_RS04990	COG2723	6-phospho-beta-galactosidase activity
DK181_RS05005	COG1307	EDD domain protein, DegV family
DK181_RS05010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DK181_RS05020	COG0488	(ABC) transporter
DK181_RS05040	COG1132	(ABC) transporter
DK181_RS05065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DK181_RS05080	COG1131	(ABC) transporter
DK181_RS05090	COG0737	Belongs to the 5'-nucleotidase family
DK181_RS05105	COG1132	(ABC) transporter
DK181_RS05135	COG2357	RelA SpoT domain protein
DK181_RS05140	COG0745	RESPONSE REGULATOR receiver
DK181_RS05145	COG5002	protein histidine kinase activity
DK181_RS05165	COG3759	membrane
DK181_RS05175	COG0719	Fe-S assembly protein
DK181_RS05180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK181_RS05185	COG2233	PERMEase
DK181_RS05200	COG0604	alcohol dehydrogenase
DK181_RS05205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DK181_RS05215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DK181_RS05220	COG2890	protein-(glutamine-N5) methyltransferase activity
DK181_RS05245	COG0741	lytic transglycosylase activity
DK181_RS05250	COG1132	(ABC) transporter
DK181_RS05255	COG1132	(ABC) transporter
DK181_RS05260	COG0346	lactoylglutathione lyase activity
DK181_RS05280	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DK181_RS05285	COG0628	permease
DK181_RS05300	COG0720	synthase
DK181_RS05305	COG0602	queuosine metabolic process
DK181_RS05310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DK181_RS05315	COG4974	Belongs to the 'phage' integrase family
DK181_RS05325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DK181_RS05330	COG0456	acetyltransferase
DK181_RS05345	COG2188	Transcriptional regulator
DK181_RS05365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DK181_RS05375	COG1177	transmembrane transport
DK181_RS05380	COG1176	ABC-type spermidine putrescine transport system, permease component I
DK181_RS05390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DK181_RS05415	COG0285	dihydrofolate synthase activity
DK181_RS05420	COG2962	Rard protein
DK181_RS05455	COG1131	(ABC) transporter
DK181_RS05460	COG1309	transcriptional regulator
DK181_RS05465	COG2267	carboxylic ester hydrolase activity
DK181_RS05495	COG1272	protein, Hemolysin III
DK181_RS05515	COG1304	FMN binding
DK181_RS05540	COG1473	amidohydrolase
DK181_RS05545	COG0435	Glutathione S-transferase
DK181_RS05550	COG0435	Glutathione S-transferase
DK181_RS05560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS05570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS05575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK181_RS05585	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DK181_RS05585	COG0392	lysyltransferase activity
DK181_RS05590	COG2267	carboxylic ester hydrolase activity
DK181_RS05625	COG0438	transferase activity, transferring glycosyl groups
DK181_RS05630	COG0438	transferase activity, transferring glycosyl groups
DK181_RS05645	COG1442	glycosyl transferase family 8
DK181_RS05645	COG1216	Glycosyl transferase, family 2
DK181_RS05665	COG0562	UDP-galactopyranose mutase
DK181_RS05685	COG0110	maltose O-acetyltransferase activity
DK181_RS05705	COG0222	ribosome binding
DK181_RS05710	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DK181_RS05715	COG2040	homocysteine
DK181_RS05720	COG0833	amino acid
DK181_RS05730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DK181_RS05740	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DK181_RS05745	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DK181_RS05750	COG3425	synthase
DK181_RS05765	COG0561	phosphatase activity
DK181_RS05780	COG4221	oxidoreductase activity
DK181_RS05785	COG0280	phosphate acetyltransferase
DK181_RS05790	COG0564	pseudouridine synthase activity
DK181_RS05800	COG2357	RelA SpoT domain protein
DK181_RS05815	COG1104	cysteine desulfurase activity
DK181_RS05825	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DK181_RS05830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK181_RS05835	COG2003	Belongs to the UPF0758 family
DK181_RS05840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK181_RS05840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS05840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK181_RS05845	COG1105	Belongs to the carbohydrate kinase PfkB family
DK181_RS05850	COG1349	DNA-binding transcription factor activity
DK181_RS05870	COG0336	Belongs to the RNA methyltransferase TrmD family
DK181_RS05875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DK181_RS05895	COG3237	CsbD-like
DK181_RS05930	COG0228	four-way junction DNA binding
DK181_RS05945	COG0300	oxidoreductase activity
DK181_RS05955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK181_RS05960	COG0577	efflux transmembrane transporter activity
DK181_RS05965	COG1136	(ABC) transporter
DK181_RS06050	COG2274	protein secretion by the type I secretion system
DK181_RS06055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK181_RS06060	COG3290	protein histidine kinase activity
DK181_RS06075	COG0442	prolyl-tRNA aminoacylation
DK181_RS06085	COG4667	esterase of the alpha-beta hydrolase superfamily
DK181_RS06110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DK181_RS06120	COG0758	DNA mediated transformation
DK181_RS06125	COG0110	maltose O-acetyltransferase activity
DK181_RS06140	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK181_RS06150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK181_RS06165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DK181_RS06175	COG0583	DNA-binding transcription factor activity
DK181_RS06180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DK181_RS06185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK181_RS06200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DK181_RS06205	COG4684	Psort location CytoplasmicMembrane, score
DK181_RS06210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DK181_RS06225	COG3764	Sortase (surface protein transpeptidase)
DK181_RS06245	COG1174	glycine betaine transport
DK181_RS06270	COG0297	glycogen (starch) synthase activity
DK181_RS06275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DK181_RS06280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DK181_RS06285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DK181_RS06290	COG1523	belongs to the glycosyl hydrolase 13 family
DK181_RS06295	COG1079	Belongs to the binding-protein-dependent transport system permease family
DK181_RS06300	COG4603	Belongs to the binding-protein-dependent transport system permease family
DK181_RS06305	COG3845	ABC transporter
DK181_RS06310	COG1744	ABC transporter substrate-binding protein PnrA-like
DK181_RS06330	COG2813	Specifically methylates the guanine in position
DK181_RS06335	COG1072	(Pantothenic acid kinase))
DK181_RS06345	COG5002	protein histidine kinase activity
DK181_RS06350	COG0745	RESPONSE REGULATOR receiver
DK181_RS06360	COG0704	Plays a role in the regulation of phosphate uptake
DK181_RS06365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK181_RS06375	COG0581	inorganic phosphate transmembrane transporter activity
DK181_RS06380	COG0573	inorganic phosphate transmembrane transporter activity
DK181_RS06390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK181_RS06390	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DK181_RS06400	COG0483	inositol monophosphate 1-phosphatase activity
DK181_RS06405	COG4476	Belongs to the UPF0223 family
DK181_RS06410	COG1393	Belongs to the ArsC family
DK181_RS06415	COG0196	riboflavin kinase activity
DK181_RS06420	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DK181_RS06440	COG0366	Alpha amylase catalytic
DK181_RS06440	COG5263	repeat protein
DK181_RS06450	COG1914	H( )-stimulated, divalent metal cation uptake system
DK181_RS06455	COG0366	Alpha amylase catalytic
DK181_RS06455	COG5263	repeat protein
DK181_RS06485	COG1053	succinate dehydrogenase
DK181_RS06485	COG0431	NADPH-dependent FMN reductase
DK181_RS06485	COG3976	FMN-binding domain protein
DK181_RS06495	COG1917	Cupin 2, conserved barrel domain protein
DK181_RS06495	COG2207	Transcriptional regulator
DK181_RS06500	COG1126	abc transporter atp-binding protein
DK181_RS06505	COG0765	amino acid transport
DK181_RS06510	COG0765	amino acid transport
DK181_RS06515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS06525	COG0148	phosphopyruvate hydratase activity
DK181_RS06575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK181_RS06575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK181_RS06580	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK181_RS06585	COG3711	transcriptional antiterminator
DK181_RS06590	COG3684	Belongs to the aldolase LacD family
DK181_RS06620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DK181_RS06630	COG0366	Alpha amylase catalytic
DK181_RS06635	COG3842	ATPase activity
DK181_RS06640	COG0366	Alpha amylase catalytic
DK181_RS06645	COG0395	ABC-type sugar transport system, permease component
DK181_RS06650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DK181_RS06655	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DK181_RS06665	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DK181_RS06680	COG0646	methionine synthase
DK181_RS06680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DK181_RS06685	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK181_RS06690	COG0542	response to heat
DK181_RS06695	COG0542	response to heat
DK181_RS06700	COG0542	response to heat
DK181_RS06705	COG1396	sequence-specific DNA binding
DK181_RS06720	COG2723	6-phospho-beta-galactosidase activity
DK181_RS06725	COG2190	(PTS) system
DK181_RS06725	COG1263	PTS System
DK181_RS06725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK181_RS06730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK181_RS06740	COG0077	Prephenate dehydratase
DK181_RS06745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DK181_RS06750	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DK181_RS06755	COG0726	polysaccharide deacetylase
DK181_RS06760	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DK181_RS06765	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DK181_RS06770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DK181_RS06805	COG0481	GTPase activity
DK181_RS06820	COG0647	UMP catabolic process
DK181_RS06830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DK181_RS06845	COG1074	ATP-dependent DNA helicase activity
DK181_RS06850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DK181_RS06875	COG3715	PTS system
DK181_RS06885	COG3842	ATPase activity
DK181_RS06900	COG0419	ATPase involved in DNA repair
DK181_RS06905	COG0420	3'-5' exonuclease activity
DK181_RS06910	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DK181_RS06945	COG0463	Glycosyl transferase, family 2
DK181_RS06960	COG1368	sulfuric ester hydrolase activity
DK181_RS06985	COG0463	Glycosyl transferase, family 2
DK181_RS06995	COG1091	dTDP-4-dehydrorhamnose reductase activity
DK181_RS07000	COG0463	Glycosyl transferase, family 2
DK181_RS07005	COG2151	metal-sulfur cluster biosynthetic enzyme
DK181_RS07010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DK181_RS07015	COG0358	DNA primase activity
DK181_RS07020	COG1970	mechanosensitive ion channel activity
DK181_RS07025	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DK181_RS07045	COG1811	Na channel or pump
DK181_RS07050	COG0556	nucleotide-excision repair
DK181_RS07070	COG1126	abc transporter atp-binding protein
DK181_RS07075	COG0488	(ABC) transporter
DK181_RS07095	COG1187	pseudouridine synthase activity
DK181_RS07125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK181_RS07130	COG3442	glutamine amidotransferase
DK181_RS07150	COG0095	Lipoate-protein ligase
DK181_RS07160	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK181_RS07165	COG0022	dehydrogenase e1 component
DK181_RS07165	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK181_RS07170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DK181_RS07175	COG0488	(ABC) transporter
DK181_RS07215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK181_RS07235	COG0385	Bile acid
DK181_RS07240	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK181_RS07255	COG1309	transcriptional regulator
DK181_RS07260	COG2249	NAD(P)H dehydrogenase (quinone) activity
DK181_RS07265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DK181_RS07270	COG0768	penicillin binding
DK181_RS07275	COG0588	phosphoglycerate mutase activity
DK181_RS07280	COG0167	dihydroorotate dehydrogenase activity
DK181_RS07300	COG2755	lipolytic protein G-D-S-L family
DK181_RS07305	COG1307	EDD domain protein, DegV family
DK181_RS07335	COG1132	(ABC) transporter
DK181_RS07340	COG1132	(ABC) transporter
DK181_RS07355	COG4470	Protein conserved in bacteria
DK181_RS07360	COG3480	Lon protease (S16) C-terminal proteolytic domain
DK181_RS07370	COG0742	ribosomal rna small subunit methyltransferase
DK181_RS07375	COG2315	Protein conserved in bacteria
DK181_RS07400	COG0842	Transport permease protein
DK181_RS07400	COG1131	(ABC) transporter
DK181_RS07400	COG1716	ATPase activity
DK181_RS07410	COG0443	Heat shock 70 kDa protein
DK181_RS07425	COG2177	Part of the ABC transporter FtsEX involved in
DK181_RS07430	COG2884	Cell division ATP-binding protein ftsE
DK181_RS07440	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DK181_RS07455	COG0366	Alpha amylase catalytic
DK181_RS07455	COG5263	repeat protein
DK181_RS07465	COG0640	Transcriptional regulator
DK181_RS07480	COG3275	phosphorelay sensor kinase activity
DK181_RS07485	COG3279	Response regulator of the LytR AlgR family
DK181_RS07505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DK181_RS07520	COG1217	gtp-binding protein TYPA
DK181_RS07540	COG0765	amino acid transport
DK181_RS07550	COG0371	Dehydrogenase
DK181_RS07555	COG0436	Aminotransferase
DK181_RS07560	COG1126	abc transporter atp-binding protein
DK181_RS07605	COG0363	glucosamine-6-phosphate deaminase activity
DK181_RS07610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DK181_RS07635	COG1466	dna polymerase III delta subunit
DK181_RS07655	COG0658	competence protein
DK181_RS07655	COG2333	competence protein COMEC
DK181_RS07660	COG1555	photosystem II stabilization
DK181_RS07660	COG1596	polysaccharide export
DK181_RS07665	COG0204	Acyl-transferase
DK181_RS07715	COG2183	response to ionizing radiation
DK181_RS07720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DK181_RS07745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK181_RS07750	COG1254	Belongs to the acylphosphatase family
DK181_RS07790	COG0671	phosphoesterase, PA-phosphatase related
DK181_RS07795	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DK181_RS07820	COG0569	domain protein
DK181_RS07825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DK181_RS07830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DK181_RS07835	COG5002	protein histidine kinase activity
DK181_RS07840	COG0745	RESPONSE REGULATOR receiver
DK181_RS07845	COG1126	abc transporter atp-binding protein
DK181_RS07850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS07855	COG0765	amino acid transport
DK181_RS07860	COG0765	amino acid transport
DK181_RS07880	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK181_RS07880	COG1388	LysM domain
DK181_RS07885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DK181_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
DK181_RS07910	COG5002	protein histidine kinase activity
DK181_RS07915	COG0745	RESPONSE REGULATOR receiver
DK181_RS07920	COG0577	efflux transmembrane transporter activity
DK181_RS07925	COG1136	(ABC) transporter
DK181_RS07955	COG0525	valine-tRNA ligase activity
DK181_RS07965	COG1418	mRNA catabolic process
DK181_RS08020	COG1940	carbohydrate kinase activity
DK181_RS08025	COG4483	Protein conserved in bacteria
DK181_RS08030	COG0783	Belongs to the Dps family
DK181_RS08040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DK181_RS08070	COG1126	abc transporter atp-binding protein
DK181_RS08075	COG0765	amino acid transport
DK181_RS08085	COG4703	Protein of unknown function (DUF1797)
DK181_RS08090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DK181_RS08095	COG0542	response to heat
DK181_RS08105	COG0494	nUDIX hydrolase
DK181_RS08115	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DK181_RS08120	COG3599	regulation of cell shape
DK181_RS08130	COG2302	S4 RNA-binding domain
DK181_RS08145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DK181_RS08165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DK181_RS08195	COG0673	inositol 2-dehydrogenase activity
DK181_RS08210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK181_RS08210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK181_RS08225	COG0701	Predicted permease
DK181_RS08230	COG3689	TIGRFAM TIGR03943 family protein
DK181_RS08235	COG0552	protein localization to endoplasmic reticulum
DK181_RS08240	COG0561	phosphatase activity
DK181_RS08245	COG0561	phosphatase activity
DK181_RS08275	COG0667	Aldo Keto reductase
DK181_RS08315	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK181_RS08330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DK181_RS08335	COG3304	Inner membrane component domain
DK181_RS08340	COG0406	alpha-ribazole phosphatase activity
DK181_RS08360	COG1395	domain, Protein
DK181_RS08375	COG0438	transferase activity, transferring glycosyl groups
DK181_RS08400	COG1609	Transcriptional regulator
DK181_RS08405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DK181_RS08410	COG0006	proline dipeptidase activity
DK181_RS08420	COG1940	carbohydrate kinase activity
DK181_RS08430	COG0778	Nitroreductase
DK181_RS08455	COG0557	exoribonuclease II activity
DK181_RS08470	COG2814	Major facilitator Superfamily
DK181_RS08480	COG0237	dephospho-CoA kinase activity
DK181_RS08485	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DK181_RS08500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DK181_RS08515	COG1702	phosphate starvation-inducible protein PhoH
DK181_RS08545	COG4464	protein tyrosine phosphatase activity
DK181_RS08550	COG1316	TRANSCRIPTIONal
DK181_RS08575	COG0559	Belongs to the binding-protein-dependent transport system permease family
DK181_RS08585	COG4471	UPF0298 protein
DK181_RS08605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DK181_RS08610	COG0626	cystathionine gamma-synthase activity
DK181_RS08615	COG0640	Transcriptional regulator
DK181_RS08620	COG2814	Major facilitator Superfamily
DK181_RS08625	COG2244	polysaccharide biosynthetic process
DK181_RS08635	COG1120	ATPase activity
DK181_RS08640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DK181_RS08645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK181_RS08650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK181_RS08675	COG1309	transcriptional regulator
DK181_RS08680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DK181_RS08695	COG1227	inorganic diphosphatase activity
DK181_RS08705	COG3064	Membrane
DK181_RS08705	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DK181_RS08705	COG3583	domain protein
DK181_RS08720	COG2137	regulation of response to DNA damage stimulus
DK181_RS08850	COG1040	competence protein
DK181_RS08855	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DK181_RS08860	COG1739	Uncharacterized protein family UPF0029
DK181_RS08870	COG1098	S1 RNA binding domain
DK181_RS08880	COG2197	response regulator
DK181_RS08885	COG4585	Histidine kinase
DK181_RS08905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK181_RS08905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK181_RS08915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DK181_RS08920	COG1758	RNA polymerase activity
DK181_RS08945	COG1204	response to ionizing radiation
DK181_RS08965	COG0598	Magnesium transport protein CorA
DK181_RS08975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DK181_RS08980	COG0629	single-stranded DNA binding
DK181_RS08985	COG0360	Binds together with S18 to 16S ribosomal RNA
DK181_RS09035	COG2274	protein secretion by the type I secretion system
DK181_RS09040	COG1194	a g-specific adenine glycosylase
DK181_RS09050	COG1063	alcohol dehydrogenase
DK181_RS09055	COG3118	belongs to the thioredoxin family
DK181_RS09070	COG2217	Heavy metal translocating P-type atpase
DK181_RS09085	COG1137	ATPase activity
DK181_RS09095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DK181_RS09100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DK181_RS09110	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DK181_RS09115	COG0195	Participates in both transcription termination and antitermination
DK181_RS09145	COG4473	ABC transporter
DK181_RS09150	COG1131	(ABC) transporter
DK181_RS09155	COG0537	adenosine 5'-monophosphoramidase activity
DK181_RS09165	COG1316	TRANSCRIPTIONal
DK181_RS09175	COG0802	atpase or kinase
DK181_RS09180	COG2252	PERMEase
DK181_RS09195	COG0561	phosphatase activity
DK181_RS09205	COG3715	PTS system
DK181_RS09210	COG3716	PTS system mannose fructose sorbose family IID component
DK181_RS09225	COG3715	PTS system
DK181_RS09230	COG3716	PTS system mannose fructose sorbose family IID component
DK181_RS09245	COG1136	(ABC) transporter
DK181_RS09245	COG0577	efflux transmembrane transporter activity
DK181_RS09275	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DK181_RS09280	COG0439	Biotin carboxylase
DK181_RS09285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DK181_RS09295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DK181_RS09300	COG1028	Short-chain dehydrogenase reductase Sdr
DK181_RS09305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DK181_RS09310	COG2070	2-Nitropropane dioxygenase
DK181_RS09320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DK181_RS09330	COG1024	Enoyl-CoA hydratase
DK181_RS09335	COG0546	phosphoglycolate phosphatase activity
DK181_RS09340	COG0527	aspartate kinase activity
DK181_RS09345	COG1686	Belongs to the peptidase S11 family
DK181_RS09350	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DK181_RS09365	COG1045	serine acetyltransferase
DK181_RS09375	COG1185	polyribonucleotide nucleotidyltransferase activity
DK181_RS09385	COG1454	alcohol dehydrogenase
DK181_RS09385	COG1012	belongs to the aldehyde dehydrogenase family
DK181_RS09400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DK181_RS09415	COG2814	Major facilitator Superfamily
DK181_RS09445	COG0431	NADPH-dependent FMN reductase
DK181_RS09455	COG2176	DNA-directed DNA polymerase activity
DK181_RS09470	COG1268	BioY protein
DK181_RS09480	COG0343	queuine tRNA-ribosyltransferase activity
DK181_RS09485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK181_RS09485	COG2190	(PTS) system
DK181_RS09485	COG1263	PTS System
DK181_RS09505	COG0058	SHG alpha-glucan phosphorylase activity
DK181_RS09510	COG1640	4-alpha-glucanotransferase
DK181_RS09515	COG2188	Transcriptional regulator
DK181_RS09520	COG2910	NAD(P)H-binding
DK181_RS09530	COG2918	glutathione biosynthetic process
DK181_RS09530	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK181_RS09540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DK181_RS09555	COG0673	inositol 2-dehydrogenase activity
DK181_RS09560	COG0673	inositol 2-dehydrogenase activity
DK181_RS09575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK181_RS09580	COG0564	pseudouridine synthase activity
DK181_RS09595	COG0459	protein refolding
DK181_RS09605	COG0561	phosphatase activity
DK181_RS09620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK181_RS09625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DK181_RS09635	COG1363	Peptidase, m42
DK181_RS09640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DK181_RS09660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK181_RS09675	COG0756	dUTP diphosphatase activity
DK181_RS09685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DK181_RS09715	COG3711	transcriptional antiterminator
DK181_RS09730	COG3732	PTS system glucitol sorbitol-specific
DK181_RS09735	COG3730	PTS system glucitol sorbitol-specific
DK181_RS09745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS09745	COG3711	transcriptional antiterminator
DK181_RS09755	COG0166	Belongs to the GPI family
DK181_RS09780	COG1234	tRNA 3'-trailer cleavage
DK181_RS09795	COG4589	Belongs to the CDS family
DK181_RS09800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DK181_RS09815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DK181_RS09840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK181_RS09850	COG3711	transcriptional antiterminator
DK181_RS09850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS09870	COG0542	response to heat
DK181_RS09875	COG4463	regulation of RNA biosynthetic process
DK181_RS09890	COG0531	amino acid
DK181_RS09900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DK181_RS09905	COG0531	amino acid
DK181_RS09910	COG2957	Belongs to the agmatine deiminase family
DK181_RS09915	COG0549	Belongs to the carbamate kinase family
DK181_RS09930	COG3590	peptidase
DK181_RS09935	COG0366	Alpha amylase catalytic
DK181_RS09940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK181_RS09940	COG1263	PTS System
DK181_RS09945	COG2188	Transcriptional regulator
DK181_RS09980	COG1136	(ABC) transporter
DK181_RS10000	COG1490	D-aminoacyl-tRNA deacylase activity
DK181_RS10010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DK181_RS10020	COG2264	protein methyltransferase activity
DK181_RS10040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DK181_RS10065	COG1473	amidohydrolase
DK181_RS10070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DK181_RS10075	COG0457	Tetratricopeptide repeat
DK181_RS10075	COG0705	Rhomboid family
DK181_RS10080	COG3022	response to hydroperoxide
DK181_RS10085	COG0602	queuosine metabolic process
DK181_RS10095	COG4472	Bacterial protein of unknown function (DUF965)
DK181_RS10100	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DK181_RS10100	COG1328	CTP reductase activity
DK181_RS10115	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DK181_RS10130	COG1393	Belongs to the ArsC family
DK181_RS10160	COG0519	Catalyzes the synthesis of GMP from XMP
DK181_RS10165	COG0632	four-way junction helicase activity
DK181_RS10180	COG4550	Control of competence regulator ComK, YlbF/YmcA
DK181_RS10205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK181_RS10235	COG1131	(ABC) transporter
DK181_RS10260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK181_RS10275	COG3177	Filamentation induced by cAMP protein fic
DK181_RS10315	COG1511	domain protein
DK181_RS10335	COG0305	Participates in initiation and elongation during chromosome replication
DK181_RS10360	COG2095	MarC family integral membrane protein
DK181_RS10365	COG0482	sulfurtransferase activity
DK181_RS10375	COG0741	lytic transglycosylase activity
DK181_RS10380	COG1388	LysM domain
DK181_RS10380	COG3858	chitin binding
DK181_RS10385	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DK181_RS10390	COG1122	ATPase activity
DK181_RS10395	COG1122	ATPase activity
DK181_RS10400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DK181_RS10410	COG0612	Peptidase, M16
DK181_RS10415	COG0612	Peptidase, M16
DK181_RS10430	COG0517	IMP dehydrogenase activity
DK181_RS10430	COG0516	GMP reductase activity
DK181_RS10440	COG0488	(ABC) transporter
DK181_RS10465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DK181_RS10470	COG1475	DNA binding