locus-tag	class	description
DK181_RS00010	COG0592	DNA-directed DNA polymerase activity
DK181_RS00020	COG1597	lipid kinase activity
DK181_RS00025	COG0012	GTP binding
DK181_RS00030	COG0193	aminoacyl-tRNA hydrolase activity
DK181_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DK181_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DK181_RS00060	COG0037	tRNA processing
DK181_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DK181_RS00075	COG0531	amino acid
DK181_RS00210	COG3942	CHAP domain
DK181_RS00220	COG0436	Aminotransferase
DK181_RS00225	COG1381	Involved in DNA repair and RecF pathway recombination
DK181_RS00230	COG0416	fatty acid biosynthetic process
DK181_RS00235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK181_RS00245	COG1131	(ABC) transporter
DK181_RS00275	COG2274	protein secretion by the type I secretion system
DK181_RS00290	COG1136	(ABC) transporter
DK181_RS00300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DK181_RS00305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DK181_RS00320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DK181_RS00325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DK181_RS00340	COG0138	bifunctional purine biosynthesis protein purh
DK181_RS00380	COG0151	Belongs to the GarS family
DK181_RS00385	COG1683	Conserved Protein
DK181_RS00395	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DK181_RS00430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DK181_RS00435	COG1012	belongs to the aldehyde dehydrogenase family
DK181_RS00525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DK181_RS00530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DK181_RS00540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DK181_RS00570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DK181_RS00575	COG0534	Mate efflux family protein
DK181_RS00580	COG1028	Short-chain dehydrogenase reductase Sdr
DK181_RS00590	COG0051	transcription antitermination factor activity, RNA binding
DK181_RS00595	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DK181_RS00610	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DK181_RS00630	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DK181_RS00660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DK181_RS00695	COG0201	protein transport
DK181_RS00700	COG0563	adenylate kinase activity
DK181_RS00725	COG0202	RNA polymerase activity
DK181_RS00765	COG1121	(ABC) transporter
DK181_RS00770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK181_RS00780	COG4499	WXG100 protein secretion system (Wss), protein YukC
DK181_RS00780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK181_RS00800	COG4166	transmembrane transport
DK181_RS00805	COG0601	transmembrane transport
DK181_RS00810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK181_RS00815	COG0444	Belongs to the ABC transporter superfamily
DK181_RS00820	COG4608	Belongs to the ABC transporter superfamily
DK181_RS00825	COG2814	Major facilitator Superfamily
DK181_RS00885	COG0583	DNA-binding transcription factor activity
DK181_RS00900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DK181_RS00910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DK181_RS00915	COG1459	type II secretion system
DK181_RS00960	COG0827	DNA restriction-modification system
DK181_RS00970	COG0583	DNA-binding transcription factor activity
DK181_RS00975	COG3830	Belongs to the UPF0237 family
DK181_RS01000	COG0588	phosphoglycerate mutase activity
DK181_RS01005	COG1876	peptidase activity
DK181_RS01010	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK181_RS01015	COG1420	regulation of RNA biosynthetic process
DK181_RS01020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DK181_RS01030	COG0484	heat shock protein binding
DK181_RS01040	COG0351	phosphomethylpyrimidine kinase
DK181_RS01045	COG4720	Psort location CytoplasmicMembrane, score
DK181_RS01055	COG0668	transmembrane transport
DK181_RS01075	COG0504	CTP synthase activity
DK181_RS01085	COG0191	fructose-bisphosphate aldolase activity
DK181_RS01095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DK181_RS01105	COG1461	Dihydroxyacetone kinase
DK181_RS01110	COG0028	Belongs to the TPP enzyme family
DK181_RS01115	COG0440	acetolactate synthase activity
DK181_RS01120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DK181_RS01155	COG4175	Glycine betaine
DK181_RS01155	COG3448	diguanylate cyclase activity
DK181_RS01175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK181_RS01175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK181_RS01180	COG1832	CoA-binding protein
DK181_RS01185	COG0735	belongs to the Fur family
DK181_RS01190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DK181_RS01200	COG1114	Component of the transport system for branched-chain amino acids
DK181_RS01210	COG0765	amino acid transport
DK181_RS01230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK181_RS01240	COG0719	Fe-S assembly protein
DK181_RS01245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DK181_RS01260	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK181_RS01260	COG3942	CHAP domain
DK181_RS01280	COG1522	sequence-specific DNA binding
DK181_RS01285	COG1335	isochorismatase
DK181_RS01295	COG3201	nicotinamide mononucleotide transporter
DK181_RS01310	COG0137	argininosuccinate synthase activity
DK181_RS01330	COG0594	ribonuclease P activity
DK181_RS01340	COG1847	R3H domain protein
DK181_RS01405	COG5433	transposase activity
DK181_RS01425	COG1696	Membrane protein involved in D-alanine export
DK181_RS01430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK181_RS01435	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DK181_RS01440	COG4808	Protein conserved in bacteria
DK181_RS01460	COG2755	lipolytic protein G-D-S-L family
DK181_RS01460	COG0657	acetylesterase activity
DK181_RS01470	COG5433	transposase activity
DK181_RS01475	COG1733	regulation of RNA biosynthetic process
DK181_RS01485	COG0084	hydrolase, TatD family'
DK181_RS01505	COG0693	protein deglycase activity
DK181_RS01580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK181_RS01590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DK181_RS01595	COG0049	tRNA binding
DK181_RS01615	COG0126	phosphoglycerate kinase activity
DK181_RS01635	COG0789	Transcriptional regulator
DK181_RS01640	COG0174	glutamine synthetase
DK181_RS01645	COG3942	CHAP domain
DK181_RS01660	COG1214	PFAM Peptidase M22, glycoprotease
DK181_RS01675	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DK181_RS01685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DK181_RS01695	COG2081	HI0933 family
DK181_RS01710	COG2176	DNA-directed DNA polymerase activity
DK181_RS01715	COG0789	Transcriptional regulator
DK181_RS01725	COG3579	cysteine-type endopeptidase activity
DK181_RS01735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK181_RS01750	COG3599	regulation of cell shape
DK181_RS01760	COG0116	Belongs to the methyltransferase superfamily
DK181_RS01775	COG1854	S-ribosylhomocysteine lyase activity
DK181_RS01790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS01820	COG1131	(ABC) transporter
DK181_RS01850	COG0768	penicillin binding
DK181_RS01855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK181_RS01860	COG0513	Belongs to the DEAD box helicase family
DK181_RS01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS01870	COG0765	amino acid transport
DK181_RS01875	COG1126	abc transporter atp-binding protein
DK181_RS01890	COG1113	amino acid transport
DK181_RS01895	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DK181_RS01940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DK181_RS01955	COG1882	Formate acetyltransferase
DK181_RS01980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DK181_RS01985	COG0681	Belongs to the peptidase S26 family
DK181_RS01990	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DK181_RS02015	COG0561	phosphatase activity
DK181_RS02060	COG1846	Transcriptional regulator
DK181_RS02065	COG1673	EVE domain
DK181_RS02125	COG2814	Major facilitator Superfamily
DK181_RS02150	COG0006	proline dipeptidase activity
DK181_RS02155	COG2131	deaminase
DK181_RS02170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DK181_RS02180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK181_RS02185	COG1733	regulation of RNA biosynthetic process
DK181_RS02195	COG1609	Transcriptional regulator
DK181_RS02200	COG1621	beta-fructofuranosidase activity
DK181_RS02205	COG2190	(PTS) system
DK181_RS02205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK181_RS02205	COG1263	PTS System
DK181_RS02210	COG1940	carbohydrate kinase activity
DK181_RS02215	COG1482	cell wall glycoprotein biosynthetic process
DK181_RS02220	COG5433	transposase activity
DK181_RS02225	COG0653	protein targeting
DK181_RS02230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DK181_RS02245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DK181_RS02250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DK181_RS02265	COG0252	asparaginase activity
DK181_RS02270	COG0561	phosphatase activity
DK181_RS02280	COG0436	Aminotransferase
DK181_RS02300	COG0732	type I restriction modification DNA specificity domain
DK181_RS02315	COG1335	isochorismatase
DK181_RS02325	COG1136	(ABC) transporter
DK181_RS02365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK181_RS02385	COG1028	Short-chain dehydrogenase reductase Sdr
DK181_RS02415	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DK181_RS02420	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK181_RS02430	COG1534	Rna-binding protein
DK181_RS02435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DK181_RS02440	COG1713	HD superfamily hydrolase involved in NAD metabolism
DK181_RS02450	COG0799	negative regulation of ribosome biogenesis
DK181_RS02455	COG2226	methyltransferase
DK181_RS02470	COG0789	Transcriptional regulator
DK181_RS02495	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DK181_RS02500	COG1461	Dihydroxyacetone kinase
DK181_RS02505	COG2376	Dihydroxyacetone kinase
DK181_RS02510	COG0217	transcriptional regulatory protein
DK181_RS02520	COG0640	Transcriptional regulator
DK181_RS02525	COG0640	Transcriptional regulator
DK181_RS02530	COG0517	IMP dehydrogenase activity
DK181_RS02535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DK181_RS02540	COG0470	DNA polymerase III
DK181_RS02545	COG1774	PSP1 C-terminal conserved region
DK181_RS02550	COG4467	Involved in initiation control of chromosome replication
DK181_RS02560	COG0004	ammonium transporteR
DK181_RS02565	COG0347	Belongs to the P(II) protein family
DK181_RS02570	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DK181_RS02575	COG0372	Belongs to the citrate synthase family
DK181_RS02600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DK181_RS02610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DK181_RS02615	COG1393	Belongs to the ArsC family
DK181_RS02620	COG0477	Major facilitator Superfamily
DK181_RS02635	COG1396	sequence-specific DNA binding
DK181_RS02740	COG0708	Exodeoxyribonuclease III
DK181_RS02750	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DK181_RS02755	COG0081	regulation of translation
DK181_RS02770	COG2996	Protein conserved in bacteria
DK181_RS02775	COG0456	acetyltransferase
DK181_RS02775	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DK181_RS02780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS02790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK181_RS02805	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DK181_RS02820	COG1122	ATPase activity
DK181_RS02835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DK181_RS02840	COG0357	Ribosomal RNA small subunit methyltransferase G
DK181_RS02845	COG1704	LemA family
DK181_RS02850	COG0501	Belongs to the peptidase M48B family
DK181_RS02865	COG0745	RESPONSE REGULATOR receiver
DK181_RS02880	COG1484	DNA-dependent DNA replication
DK181_RS02915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DK181_RS02935	COG1254	Belongs to the acylphosphatase family
DK181_RS02940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK181_RS02970	COG2183	response to ionizing radiation
DK181_RS03020	COG0204	Acyl-transferase
DK181_RS03025	COG1555	photosystem II stabilization
DK181_RS03025	COG1596	polysaccharide export
DK181_RS03030	COG2333	competence protein COMEC
DK181_RS03030	COG0658	competence protein
DK181_RS03050	COG1466	dna polymerase III delta subunit
DK181_RS03075	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DK181_RS03080	COG0363	glucosamine-6-phosphate deaminase activity
DK181_RS03130	COG0436	Aminotransferase
DK181_RS03135	COG0371	Dehydrogenase
DK181_RS03170	COG1217	gtp-binding protein TYPA
DK181_RS03205	COG3279	Response regulator of the LytR AlgR family
DK181_RS03225	COG0640	Transcriptional regulator
DK181_RS03235	COG0366	Alpha amylase catalytic
DK181_RS03235	COG5263	repeat protein
DK181_RS03250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DK181_RS03260	COG2884	Cell division ATP-binding protein ftsE
DK181_RS03265	COG2177	Part of the ABC transporter FtsEX involved in
DK181_RS03280	COG0443	Heat shock 70 kDa protein
DK181_RS03290	COG1116	anion transmembrane transporter activity
DK181_RS03315	COG2315	Protein conserved in bacteria
DK181_RS03320	COG0742	ribosomal rna small subunit methyltransferase
DK181_RS03330	COG3480	Lon protease (S16) C-terminal proteolytic domain
DK181_RS03335	COG4470	Protein conserved in bacteria
DK181_RS03350	COG1132	(ABC) transporter
DK181_RS03355	COG1132	(ABC) transporter
DK181_RS03385	COG1307	EDD domain protein, DegV family
DK181_RS03390	COG2755	lipolytic protein G-D-S-L family
DK181_RS03410	COG0167	dihydroorotate dehydrogenase activity
DK181_RS03415	COG0588	phosphoglycerate mutase activity
DK181_RS03420	COG0768	penicillin binding
DK181_RS03425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DK181_RS03430	COG2249	NAD(P)H dehydrogenase (quinone) activity
DK181_RS03435	COG1309	transcriptional regulator
DK181_RS03450	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK181_RS03455	COG0385	Bile acid
DK181_RS03465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK181_RS03505	COG0488	(ABC) transporter
DK181_RS03510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DK181_RS03515	COG0022	dehydrogenase e1 component
DK181_RS03515	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK181_RS03520	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK181_RS03530	COG0095	Lipoate-protein ligase
DK181_RS03550	COG3442	glutamine amidotransferase
DK181_RS03555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK181_RS03600	COG0488	(ABC) transporter
DK181_RS03605	COG1126	abc transporter atp-binding protein
DK181_RS03620	COG0556	nucleotide-excision repair
DK181_RS03625	COG1811	Na channel or pump
DK181_RS03645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DK181_RS03650	COG1970	mechanosensitive ion channel activity
DK181_RS03655	COG0358	DNA primase activity
DK181_RS03660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DK181_RS03665	COG2151	metal-sulfur cluster biosynthetic enzyme
DK181_RS03670	COG0463	Glycosyl transferase, family 2
DK181_RS03675	COG1091	dTDP-4-dehydrorhamnose reductase activity
DK181_RS03685	COG1215	transferase activity, transferring glycosyl groups
DK181_RS03710	COG1368	sulfuric ester hydrolase activity
DK181_RS03725	COG0463	Glycosyl transferase, family 2
DK181_RS03760	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DK181_RS03765	COG0420	3'-5' exonuclease activity
DK181_RS03770	COG0419	ATPase involved in DNA repair
DK181_RS03785	COG1122	ATPase activity
DK181_RS03795	COG3715	PTS system
DK181_RS03820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DK181_RS03825	COG1074	ATP-dependent DNA helicase activity
DK181_RS03845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DK181_RS03855	COG0647	UMP catabolic process
DK181_RS03870	COG0481	GTPase activity
DK181_RS03905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DK181_RS03910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DK181_RS03915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DK181_RS03920	COG0726	polysaccharide deacetylase
DK181_RS03925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DK181_RS03930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DK181_RS03935	COG0077	Prephenate dehydratase
DK181_RS03945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK181_RS03950	COG2190	(PTS) system
DK181_RS03950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK181_RS03950	COG1263	PTS System
DK181_RS03955	COG2723	6-phospho-beta-galactosidase activity
DK181_RS03970	COG1396	sequence-specific DNA binding
DK181_RS03975	COG0542	response to heat
DK181_RS03980	COG0542	response to heat
DK181_RS03990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK181_RS03995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DK181_RS03995	COG0646	methionine synthase
DK181_RS04010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DK181_RS04020	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DK181_RS04025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DK181_RS04030	COG0395	ABC-type sugar transport system, permease component
DK181_RS04035	COG0366	Alpha amylase catalytic
DK181_RS04040	COG3842	ATPase activity
DK181_RS04045	COG0366	Alpha amylase catalytic
DK181_RS04055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DK181_RS04085	COG3684	Belongs to the aldolase LacD family
DK181_RS04090	COG3711	transcriptional antiterminator
DK181_RS04095	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK181_RS04100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK181_RS04100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK181_RS04145	COG0148	phosphopyruvate hydratase activity
DK181_RS04155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS04160	COG0765	amino acid transport
DK181_RS04165	COG0765	amino acid transport
DK181_RS04170	COG1126	abc transporter atp-binding protein
DK181_RS04175	COG2207	Transcriptional regulator
DK181_RS04175	COG1917	Cupin 2, conserved barrel domain protein
DK181_RS04180	COG5433	transposase activity
DK181_RS04190	COG3976	FMN-binding domain protein
DK181_RS04190	COG0431	NADPH-dependent FMN reductase
DK181_RS04190	COG1053	succinate dehydrogenase
DK181_RS04195	COG3976	FMN-binding domain protein
DK181_RS04195	COG0431	NADPH-dependent FMN reductase
DK181_RS04195	COG1053	succinate dehydrogenase
DK181_RS04220	COG0366	Alpha amylase catalytic
DK181_RS04220	COG5263	repeat protein
DK181_RS04225	COG1914	H( )-stimulated, divalent metal cation uptake system
DK181_RS04235	COG0366	Alpha amylase catalytic
DK181_RS04235	COG5263	repeat protein
DK181_RS04255	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DK181_RS04260	COG0196	riboflavin kinase activity
DK181_RS04265	COG1393	Belongs to the ArsC family
DK181_RS04270	COG4476	Belongs to the UPF0223 family
DK181_RS04275	COG0483	inositol monophosphate 1-phosphatase activity
DK181_RS04285	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DK181_RS04285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK181_RS04295	COG0573	inorganic phosphate transmembrane transporter activity
DK181_RS04300	COG0581	inorganic phosphate transmembrane transporter activity
DK181_RS04310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK181_RS04315	COG0704	Plays a role in the regulation of phosphate uptake
DK181_RS04325	COG0745	RESPONSE REGULATOR receiver
DK181_RS04330	COG5002	protein histidine kinase activity
DK181_RS04340	COG1072	(Pantothenic acid kinase))
DK181_RS04345	COG2813	Specifically methylates the guanine in position
DK181_RS04365	COG1744	ABC transporter substrate-binding protein PnrA-like
DK181_RS04370	COG3845	ABC transporter
DK181_RS04375	COG4603	Belongs to the binding-protein-dependent transport system permease family
DK181_RS04380	COG1079	Belongs to the binding-protein-dependent transport system permease family
DK181_RS04385	COG1523	belongs to the glycosyl hydrolase 13 family
DK181_RS04390	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DK181_RS04395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DK181_RS04400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DK181_RS04405	COG0297	glycogen (starch) synthase activity
DK181_RS04410	COG0058	SHG alpha-glucan phosphorylase activity
DK181_RS04430	COG1174	glycine betaine transport
DK181_RS04450	COG3764	Sortase (surface protein transpeptidase)
DK181_RS04465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DK181_RS04470	COG4684	Psort location CytoplasmicMembrane, score
DK181_RS04475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DK181_RS04490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK181_RS04495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DK181_RS04500	COG0583	DNA-binding transcription factor activity
DK181_RS04510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DK181_RS04525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK181_RS04535	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK181_RS04550	COG0110	maltose O-acetyltransferase activity
DK181_RS04555	COG0758	DNA mediated transformation
DK181_RS04565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DK181_RS04590	COG4667	esterase of the alpha-beta hydrolase superfamily
DK181_RS04615	COG3290	protein histidine kinase activity
DK181_RS04625	COG2274	protein secretion by the type I secretion system
DK181_RS04695	COG1136	(ABC) transporter
DK181_RS04700	COG0577	efflux transmembrane transporter activity
DK181_RS04705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK181_RS04715	COG0300	oxidoreductase activity
DK181_RS04730	COG0228	four-way junction DNA binding
DK181_RS04775	COG5492	domain, Protein
DK181_RS04775	COG3583	domain protein
DK181_RS04775	COG1621	beta-fructofuranosidase activity
DK181_RS04780	COG0322	excinuclease ABC activity
DK181_RS04785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK181_RS04790	COG0285	dihydrofolate synthase activity
DK181_RS04805	COG1104	cysteine desulfurase activity
DK181_RS04825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DK181_RS04855	COG5263	repeat protein
DK181_RS04855	COG0366	Alpha amylase catalytic
DK181_RS04855	COG5263	repeat protein
DK181_RS04855	COG0366	Alpha amylase catalytic
DK181_RS04865	COG0583	DNA-binding transcription factor activity
DK181_RS04875	COG0564	pseudouridine synthase activity
DK181_RS04890	COG0540	Belongs to the ATCase OTCase family
DK181_RS04895	COG0505	Belongs to the CarA family
DK181_RS04920	COG0561	phosphatase activity
DK181_RS04925	COG0346	lactoylglutathione lyase activity
DK181_RS04940	COG5433	transposase activity
DK181_RS04950	COG1307	EDD domain protein, DegV family
DK181_RS04955	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DK181_RS04965	COG0488	(ABC) transporter
DK181_RS04980	COG1132	(ABC) transporter
DK181_RS05005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DK181_RS05020	COG1131	(ABC) transporter
DK181_RS05045	COG1132	(ABC) transporter
DK181_RS05075	COG2357	RelA SpoT domain protein
DK181_RS05080	COG0745	RESPONSE REGULATOR receiver
DK181_RS05085	COG5002	protein histidine kinase activity
DK181_RS05105	COG3759	membrane
DK181_RS05120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK181_RS05125	COG2233	PERMEase
DK181_RS05155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DK181_RS05165	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DK181_RS05170	COG2890	protein-(glutamine-N5) methyltransferase activity
DK181_RS05195	COG0741	lytic transglycosylase activity
DK181_RS05205	COG1132	(ABC) transporter
DK181_RS05210	COG0346	lactoylglutathione lyase activity
DK181_RS05230	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DK181_RS05235	COG0628	permease
DK181_RS05250	COG0720	synthase
DK181_RS05255	COG0602	queuosine metabolic process
DK181_RS05260	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DK181_RS05265	COG4974	Belongs to the 'phage' integrase family
DK181_RS05275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DK181_RS05280	COG0456	acetyltransferase
DK181_RS05305	COG2188	Transcriptional regulator
DK181_RS05325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DK181_RS05330	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DK181_RS05335	COG1177	transmembrane transport
DK181_RS05340	COG1176	ABC-type spermidine putrescine transport system, permease component I
DK181_RS05350	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DK181_RS05375	COG0285	dihydrofolate synthase activity
DK181_RS05380	COG2962	Rard protein
DK181_RS05415	COG1131	(ABC) transporter
DK181_RS05420	COG1309	transcriptional regulator
DK181_RS05425	COG2267	carboxylic ester hydrolase activity
DK181_RS05455	COG1272	protein, Hemolysin III
DK181_RS05475	COG1304	FMN binding
DK181_RS05500	COG1473	amidohydrolase
DK181_RS05505	COG0435	Glutathione S-transferase
DK181_RS05510	COG0435	Glutathione S-transferase
DK181_RS05520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS05530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK181_RS05535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS05540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK181_RS05550	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DK181_RS05550	COG0392	lysyltransferase activity
DK181_RS05555	COG2267	carboxylic ester hydrolase activity
DK181_RS05590	COG0438	transferase activity, transferring glycosyl groups
DK181_RS05595	COG0438	transferase activity, transferring glycosyl groups
DK181_RS05610	COG1442	glycosyl transferase family 8
DK181_RS05610	COG1216	Glycosyl transferase, family 2
DK181_RS05630	COG0562	UDP-galactopyranose mutase
DK181_RS05650	COG0110	maltose O-acetyltransferase activity
DK181_RS05670	COG0222	ribosome binding
DK181_RS05675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DK181_RS05680	COG2040	homocysteine
DK181_RS05685	COG0833	amino acid
DK181_RS05695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DK181_RS05705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DK181_RS05710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DK181_RS05715	COG3425	synthase
DK181_RS05730	COG0561	phosphatase activity
DK181_RS05745	COG4221	oxidoreductase activity
DK181_RS05750	COG0280	phosphate acetyltransferase
DK181_RS05755	COG0564	pseudouridine synthase activity
DK181_RS05765	COG2357	RelA SpoT domain protein
DK181_RS05780	COG1104	cysteine desulfurase activity
DK181_RS05790	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DK181_RS05795	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK181_RS05800	COG2003	Belongs to the UPF0758 family
DK181_RS05805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS05805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK181_RS05805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK181_RS05810	COG1105	Belongs to the carbohydrate kinase PfkB family
DK181_RS05815	COG1349	DNA-binding transcription factor activity
DK181_RS05830	COG0336	Belongs to the RNA methyltransferase TrmD family
DK181_RS05835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DK181_RS05855	COG3237	CsbD-like
DK181_RS05870	COG1011	Hydrolase
DK181_RS05885	COG2514	catechol 2,3-dioxygenase activity
DK181_RS05890	COG1959	2 iron, 2 sulfur cluster binding
DK181_RS05955	COG3290	protein histidine kinase activity
DK181_RS06005	COG0702	epimerase
DK181_RS06010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK181_RS06015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DK181_RS06080	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DK181_RS06095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DK181_RS06100	COG1956	GAF domain-containing protein
DK181_RS06105	COG2226	methyltransferase
DK181_RS06120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DK181_RS06145	COG0513	Belongs to the DEAD box helicase family
DK181_RS06150	COG3679	Belongs to the UPF0342 family
DK181_RS06155	COG0287	Prephenate dehydrogenase
DK181_RS06170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DK181_RS06180	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DK181_RS06185	COG1368	sulfuric ester hydrolase activity
DK181_RS06205	COG0107	imidazoleglycerol-phosphate synthase activity
DK181_RS06210	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DK181_RS06215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DK181_RS06230	COG0560	Phosphoserine phosphatase
DK181_RS06235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DK181_RS06240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DK181_RS06245	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DK181_RS06255	COG0366	Alpha amylase catalytic
DK181_RS06255	COG5263	repeat protein
DK181_RS06265	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DK181_RS06305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK181_RS06345	COG0356	it plays a direct role in the translocation of protons across the membrane
DK181_RS06355	COG1597	lipid kinase activity
DK181_RS06360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DK181_RS06365	COG4708	membrane
DK181_RS06375	COG2246	polysaccharide biosynthetic process
DK181_RS06380	COG3527	Alpha-acetolactate decarboxylase
DK181_RS06385	COG0028	Belongs to the TPP enzyme family
DK181_RS06390	COG0457	Tetratricopeptide repeat
DK181_RS06395	COG0628	permease
DK181_RS06400	COG1051	belongs to the nudix hydrolase family
DK181_RS06405	COG2706	6-phosphogluconolactonase activity
DK181_RS06420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK181_RS06435	COG2384	SAM-dependent methyltransferase
DK181_RS06445	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DK181_RS06460	COG2873	o-acetylhomoserine
DK181_RS06475	COG1609	Transcriptional regulator
DK181_RS06480	COG0366	Alpha amylase catalytic
DK181_RS06490	COG1175	transmembrane transport
DK181_RS06495	COG3833	ABC-type maltose transport systems, permease component
DK181_RS06500	COG3842	ATPase activity
DK181_RS06505	COG1115	amino acid carrier protein
DK181_RS06510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DK181_RS06515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS06520	COG1126	abc transporter atp-binding protein
DK181_RS06525	COG0765	amino acid transport
DK181_RS06530	COG2824	Alkylphosphonate utilization operon protein PhnA
DK181_RS06565	COG0246	Mannitol dehydrogenase
DK181_RS06570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS06575	COG3711	transcriptional antiterminator
DK181_RS06580	COG2213	PTS system mannitol-specific
DK181_RS06595	COG0469	pyruvate kinase activity
DK181_RS06610	COG1725	Transcriptional regulator
DK181_RS06615	COG1131	(ABC) transporter
DK181_RS06645	COG0539	negative regulation of cytoplasmic translation
DK181_RS06665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DK181_RS06680	COG0187	DNA topoisomerase II activity
DK181_RS06695	COG0737	Belongs to the 5'-nucleotidase family
DK181_RS06705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DK181_RS06710	COG1881	PFAM PEBP family protein
DK181_RS06715	COG2315	Protein conserved in bacteria
DK181_RS06725	COG0284	orotidine-5'-phosphate decarboxylase activity
DK181_RS06735	COG0167	dihydroorotate dehydrogenase activity
DK181_RS06740	COG0543	2 iron, 2 sulfur cluster binding
DK181_RS06750	COG1088	dTDP-glucose 4,6-dehydratase activity
DK181_RS06760	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DK181_RS06765	COG0583	DNA-binding transcription factor activity
DK181_RS06795	COG1131	(ABC) transporter
DK181_RS06810	COG0813	purine-nucleoside phosphorylase activity
DK181_RS06825	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DK181_RS06845	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DK181_RS06865	COG1573	uracil-dna glycosylase
DK181_RS06870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK181_RS06880	COG0024	Methionine aminopeptidase
DK181_RS06885	COG4109	DRTGG domain
DK181_RS06895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DK181_RS06895	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DK181_RS06900	COG0300	oxidoreductase activity
DK181_RS06915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DK181_RS06920	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DK181_RS06925	COG0187	DNA topoisomerase II activity
DK181_RS06930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DK181_RS06935	COG0772	Belongs to the SEDS family
DK181_RS06950	COG2151	metal-sulfur cluster biosynthetic enzyme
DK181_RS06955	COG1780	Probably involved in ribonucleotide reductase function
DK181_RS06975	COG0335	large ribosomal subunit rRNA binding
DK181_RS06980	COG0038	chloride channel
DK181_RS06985	COG1605	Chorismate mutase
DK181_RS06985	COG0077	Prephenate dehydratase
DK181_RS07005	COG0716	FMN binding
DK181_RS07010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DK181_RS07015	COG0625	glutathione transferase activity
DK181_RS07020	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DK181_RS07035	COG0431	NADPH-dependent FMN reductase
DK181_RS07035	COG1053	succinate dehydrogenase
DK181_RS07035	COG3976	FMN-binding domain protein
DK181_RS07055	COG2226	methyltransferase
DK181_RS07060	COG3443	Belongs to the bacterial solute-binding protein 9 family
DK181_RS07060	COG0803	Belongs to the bacterial solute-binding protein 9 family
DK181_RS07085	COG1309	transcriptional regulator
DK181_RS07090	COG1924	4 iron, 4 sulfur cluster binding
DK181_RS07100	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DK181_RS07105	COG0251	oxidation-reduction process
DK181_RS07110	COG0371	Dehydrogenase
DK181_RS07115	COG0017	Asparaginyl-tRNA synthetase
DK181_RS07125	COG0436	Aminotransferase
DK181_RS07135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DK181_RS07135	COG1199	ATP-dependent helicase activity
DK181_RS07195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DK181_RS07225	COG1078	dGTPase activity
DK181_RS07255	COG0149	triose-phosphate isomerase activity
DK181_RS07270	COG3942	CHAP domain
DK181_RS07270	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK181_RS07285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS07290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DK181_RS07295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DK181_RS07305	COG1380	Effector of murein hydrolase LrgA
DK181_RS07310	COG1346	cytolysis
DK181_RS07320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DK181_RS07325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DK181_RS07330	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DK181_RS07335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DK181_RS07350	COG0497	DNA recombination
DK181_RS07360	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DK181_RS07375	COG1570	exodeoxyribonuclease VII activity
DK181_RS07385	COG4443	Transcriptional Coactivator p15 (PC4)
DK181_RS07390	COG0826	peptidase U32
DK181_RS07420	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DK181_RS07425	COG0583	DNA-binding transcription factor activity
DK181_RS07430	COG0281	malic enzyme
DK181_RS07450	COG0513	Belongs to the DEAD box helicase family
DK181_RS07480	COG0436	Aminotransferase
DK181_RS07485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DK181_RS07505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DK181_RS07520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DK181_RS07525	COG4122	O-methyltransferase activity
DK181_RS07555	COG0159	tryptophan synthase activity
DK181_RS07560	COG0133	tryptophan synthase activity
DK181_RS07565	COG0135	phosphoribosylanthranilate isomerase activity
DK181_RS07580	COG0512	Glutamine amidotransferase of anthranilate synthase
DK181_RS07585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DK181_RS07600	COG2197	response regulator
DK181_RS07605	COG4585	Histidine kinase
DK181_RS07615	COG1131	(ABC) transporter
DK181_RS07620	COG2851	Citrate transporter
DK181_RS07655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DK181_RS07660	COG1187	pseudouridine synthase activity
DK181_RS07665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DK181_RS07670	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DK181_RS07675	COG0582	viral genome integration into host DNA
DK181_RS07680	COG0517	IMP dehydrogenase activity
DK181_RS07685	COG0622	Phosphoesterase
DK181_RS07690	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DK181_RS07695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DK181_RS07700	COG3763	UPF0154 protein
DK181_RS07705	COG0019	diaminopimelate decarboxylase activity
DK181_RS07710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DK181_RS07715	COG0772	Belongs to the SEDS family
DK181_RS07735	COG1196	nuclear chromosome segregation
DK181_RS07745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DK181_RS07750	COG1428	Deoxynucleoside kinase
DK181_RS07755	COG4535	Mg2 and Co2 transporter CorC
DK181_RS07760	COG1119	ATPase activity
DK181_RS07765	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DK181_RS07770	COG1242	4 iron, 4 sulfur cluster binding
DK181_RS07785	COG2274	protein secretion by the type I secretion system
DK181_RS07810	COG0671	phosphoesterase, PA-phosphatase related
DK181_RS07815	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DK181_RS07840	COG0569	domain protein
DK181_RS07845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DK181_RS07850	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DK181_RS07855	COG5002	protein histidine kinase activity
DK181_RS07860	COG0745	RESPONSE REGULATOR receiver
DK181_RS07865	COG1126	abc transporter atp-binding protein
DK181_RS07870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK181_RS07875	COG0765	amino acid transport
DK181_RS07880	COG0765	amino acid transport
DK181_RS07900	COG1388	LysM domain
DK181_RS07900	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK181_RS07905	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DK181_RS07925	COG1028	Short-chain dehydrogenase reductase Sdr
DK181_RS07930	COG5002	protein histidine kinase activity
DK181_RS07935	COG0745	RESPONSE REGULATOR receiver
DK181_RS07940	COG0577	efflux transmembrane transporter activity
DK181_RS07945	COG1136	(ABC) transporter
DK181_RS07990	COG0525	valine-tRNA ligase activity
DK181_RS08000	COG1418	mRNA catabolic process
DK181_RS08040	COG2267	carboxylic ester hydrolase activity
DK181_RS08055	COG1940	carbohydrate kinase activity
DK181_RS08060	COG4483	Protein conserved in bacteria
DK181_RS08065	COG0783	Belongs to the Dps family
DK181_RS08075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DK181_RS08105	COG1126	abc transporter atp-binding protein
DK181_RS08110	COG0765	amino acid transport
DK181_RS08125	COG4703	Protein of unknown function (DUF1797)
DK181_RS08130	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DK181_RS08135	COG0542	response to heat
DK181_RS08140	COG0494	nUDIX hydrolase
DK181_RS08150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DK181_RS08155	COG3599	regulation of cell shape
DK181_RS08165	COG2302	S4 RNA-binding domain
DK181_RS08180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DK181_RS08195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DK181_RS08225	COG0673	inositol 2-dehydrogenase activity
DK181_RS08240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK181_RS08240	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK181_RS08255	COG0701	Predicted permease
DK181_RS08260	COG3689	TIGRFAM TIGR03943 family protein
DK181_RS08265	COG0552	protein localization to endoplasmic reticulum
DK181_RS08270	COG0561	phosphatase activity
DK181_RS08275	COG0561	phosphatase activity
DK181_RS08285	COG3414	Phosphotransferase system galactitol-specific IIB component
DK181_RS08345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK181_RS08360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DK181_RS08365	COG3304	Inner membrane component domain
DK181_RS08370	COG0406	alpha-ribazole phosphatase activity
DK181_RS08380	COG0742	ribosomal rna small subunit methyltransferase
DK181_RS08390	COG1395	domain, Protein
DK181_RS08405	COG0438	transferase activity, transferring glycosyl groups
DK181_RS08430	COG1609	Transcriptional regulator
DK181_RS08435	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DK181_RS08440	COG0006	proline dipeptidase activity
DK181_RS08450	COG1940	carbohydrate kinase activity
DK181_RS08460	COG0778	Nitroreductase
DK181_RS08485	COG0557	exoribonuclease II activity
DK181_RS08500	COG2814	Major facilitator Superfamily
DK181_RS08510	COG0237	dephospho-CoA kinase activity
DK181_RS08515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DK181_RS08530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DK181_RS08545	COG1702	phosphate starvation-inducible protein PhoH
DK181_RS08580	COG4464	protein tyrosine phosphatase activity
DK181_RS08585	COG1316	TRANSCRIPTIONal
DK181_RS08610	COG0559	Belongs to the binding-protein-dependent transport system permease family
DK181_RS08620	COG4471	UPF0298 protein
DK181_RS08640	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DK181_RS08645	COG0626	cystathionine gamma-synthase activity
DK181_RS08650	COG0640	Transcriptional regulator
DK181_RS08655	COG2814	Major facilitator Superfamily
DK181_RS08660	COG2244	polysaccharide biosynthetic process
DK181_RS08670	COG1120	ATPase activity
DK181_RS08675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DK181_RS08680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK181_RS08685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK181_RS08715	COG1309	transcriptional regulator
DK181_RS08720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DK181_RS08735	COG1227	inorganic diphosphatase activity
DK181_RS08745	COG3583	domain protein
DK181_RS08745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DK181_RS08745	COG3064	Membrane
DK181_RS08760	COG2137	regulation of response to DNA damage stimulus
DK181_RS08895	COG1192	Involved in chromosome partitioning
DK181_RS08975	COG0542	response to heat
DK181_RS08980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DK181_RS09105	COG1040	competence protein
DK181_RS09110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DK181_RS09115	COG1739	Uncharacterized protein family UPF0029
DK181_RS09125	COG1098	S1 RNA binding domain
DK181_RS09135	COG2197	response regulator
DK181_RS09140	COG4585	Histidine kinase
DK181_RS09160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK181_RS09160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK181_RS09170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DK181_RS09175	COG1758	RNA polymerase activity
DK181_RS09185	COG0598	Magnesium transport protein CorA
DK181_RS09195	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DK181_RS09200	COG0629	single-stranded DNA binding
DK181_RS09205	COG0360	Binds together with S18 to 16S ribosomal RNA
DK181_RS09255	COG2274	protein secretion by the type I secretion system
DK181_RS09260	COG1194	a g-specific adenine glycosylase
DK181_RS09270	COG1063	alcohol dehydrogenase
DK181_RS09275	COG3118	belongs to the thioredoxin family
DK181_RS09290	COG2217	Heavy metal translocating P-type atpase
DK181_RS09305	COG1131	(ABC) transporter
DK181_RS09315	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DK181_RS09320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DK181_RS09330	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DK181_RS09335	COG0195	Participates in both transcription termination and antitermination
DK181_RS09365	COG4473	ABC transporter
DK181_RS09370	COG1131	(ABC) transporter
DK181_RS09375	COG0537	adenosine 5'-monophosphoramidase activity
DK181_RS09385	COG1316	TRANSCRIPTIONal
DK181_RS09395	COG0802	atpase or kinase
DK181_RS09400	COG2252	PERMEase
DK181_RS09430	COG0561	phosphatase activity
DK181_RS09440	COG3715	PTS system
DK181_RS09445	COG3716	PTS system mannose fructose sorbose family IID component
DK181_RS09460	COG3715	PTS system
DK181_RS09465	COG3716	PTS system mannose fructose sorbose family IID component
DK181_RS09480	COG1136	(ABC) transporter
DK181_RS09480	COG0577	efflux transmembrane transporter activity
DK181_RS09510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DK181_RS09515	COG0439	Biotin carboxylase
DK181_RS09520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DK181_RS09530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DK181_RS09535	COG1028	Short-chain dehydrogenase reductase Sdr
DK181_RS09540	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DK181_RS09545	COG2070	2-Nitropropane dioxygenase
DK181_RS09555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DK181_RS09565	COG1024	Enoyl-CoA hydratase
DK181_RS09570	COG0546	phosphoglycolate phosphatase activity
DK181_RS09575	COG0527	aspartate kinase activity
DK181_RS09580	COG1686	Belongs to the peptidase S11 family
DK181_RS09585	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DK181_RS09600	COG1045	serine acetyltransferase
DK181_RS09610	COG1185	polyribonucleotide nucleotidyltransferase activity
DK181_RS09620	COG1012	belongs to the aldehyde dehydrogenase family
DK181_RS09620	COG1454	alcohol dehydrogenase
DK181_RS09640	COG0242	peptide deformylase activity
DK181_RS09650	COG2814	Major facilitator Superfamily
DK181_RS09680	COG0431	NADPH-dependent FMN reductase
DK181_RS09690	COG2176	DNA-directed DNA polymerase activity
DK181_RS09705	COG1268	BioY protein
DK181_RS09715	COG0343	queuine tRNA-ribosyltransferase activity
DK181_RS09720	COG2190	(PTS) system
DK181_RS09720	COG1263	PTS System
DK181_RS09720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK181_RS09730	COG0058	SHG alpha-glucan phosphorylase activity
DK181_RS09735	COG1640	4-alpha-glucanotransferase
DK181_RS09740	COG2188	Transcriptional regulator
DK181_RS09745	COG2910	NAD(P)H-binding
DK181_RS09755	COG2918	glutathione biosynthetic process
DK181_RS09755	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK181_RS09780	COG0673	inositol 2-dehydrogenase activity
DK181_RS09785	COG0673	inositol 2-dehydrogenase activity
DK181_RS09800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK181_RS09805	COG0564	pseudouridine synthase activity
DK181_RS09820	COG0459	protein refolding
DK181_RS09830	COG0561	phosphatase activity
DK181_RS09845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK181_RS09850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DK181_RS09860	COG1363	Peptidase, m42
DK181_RS09865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DK181_RS09885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK181_RS09900	COG0756	dUTP diphosphatase activity
DK181_RS09910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DK181_RS09955	COG3732	PTS system glucitol sorbitol-specific
DK181_RS09960	COG3730	PTS system glucitol sorbitol-specific
DK181_RS09970	COG3711	transcriptional antiterminator
DK181_RS09970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS09980	COG0166	Belongs to the GPI family
DK181_RS10010	COG1234	tRNA 3'-trailer cleavage
DK181_RS10025	COG4589	Belongs to the CDS family
DK181_RS10030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DK181_RS10045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DK181_RS10065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK181_RS10065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK181_RS10065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DK181_RS10070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK181_RS10085	COG3711	transcriptional antiterminator
DK181_RS10085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK181_RS10105	COG0542	response to heat
DK181_RS10110	COG4463	regulation of RNA biosynthetic process
DK181_RS10125	COG0531	amino acid
DK181_RS10135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DK181_RS10140	COG0531	amino acid
DK181_RS10145	COG2957	Belongs to the agmatine deiminase family
DK181_RS10150	COG0549	Belongs to the carbamate kinase family
DK181_RS10165	COG3590	peptidase
DK181_RS10170	COG0366	Alpha amylase catalytic
DK181_RS10175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK181_RS10175	COG1263	PTS System
DK181_RS10180	COG2188	Transcriptional regulator
DK181_RS10215	COG1136	(ABC) transporter
DK181_RS10235	COG1490	D-aminoacyl-tRNA deacylase activity
DK181_RS10245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DK181_RS10255	COG2264	protein methyltransferase activity
DK181_RS10275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DK181_RS10300	COG1473	amidohydrolase
DK181_RS10305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DK181_RS10310	COG0457	Tetratricopeptide repeat
DK181_RS10310	COG0705	Rhomboid family
DK181_RS10315	COG3022	response to hydroperoxide
DK181_RS10320	COG0602	queuosine metabolic process
DK181_RS10330	COG4472	Bacterial protein of unknown function (DUF965)
DK181_RS10335	COG1328	CTP reductase activity
DK181_RS10335	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DK181_RS10350	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DK181_RS10365	COG1393	Belongs to the ArsC family
DK181_RS10395	COG0519	Catalyzes the synthesis of GMP from XMP
DK181_RS10400	COG0632	four-way junction helicase activity
DK181_RS10420	COG4550	Control of competence regulator ComK, YlbF/YmcA
DK181_RS10445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK181_RS10505	COG5433	transposase activity
DK181_RS10525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK181_RS10590	COG1511	domain protein
DK181_RS10610	COG0305	Participates in initiation and elongation during chromosome replication
DK181_RS10635	COG2095	MarC family integral membrane protein
DK181_RS10640	COG0482	sulfurtransferase activity
DK181_RS10650	COG0741	lytic transglycosylase activity
DK181_RS10655	COG1388	LysM domain
DK181_RS10655	COG3858	chitin binding
DK181_RS10660	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DK181_RS10665	COG1122	ATPase activity
DK181_RS10670	COG1122	ATPase activity
DK181_RS10675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DK181_RS10685	COG0612	Peptidase, M16
DK181_RS10690	COG0612	Peptidase, M16
DK181_RS10705	COG0517	IMP dehydrogenase activity
DK181_RS10705	COG0516	GMP reductase activity
DK181_RS10715	COG0488	(ABC) transporter
DK181_RS10735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DK181_RS10740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DK181_RS10745	COG1475	DNA binding