locus-tag	class	description
UKS_RS00010	COG0592	DNA-directed DNA polymerase activity
UKS_RS00020	COG0012	GTP binding
UKS_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
UKS_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
UKS_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
UKS_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UKS_RS00125	COG0756	dUTP diphosphatase activity
UKS_RS00135	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
UKS_RS00150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
UKS_RS00195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UKS_RS00195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UKS_RS00200	COG1832	CoA-binding protein
UKS_RS00205	COG2855	membrane
UKS_RS00210	COG0436	Aminotransferase
UKS_RS00240	COG0791	NLP P60 protein
UKS_RS00300	COG2274	protein secretion by the type I secretion system
UKS_RS00305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UKS_RS00315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
UKS_RS00320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
UKS_RS00325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
UKS_RS00330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
UKS_RS00335	COG0138	bifunctional purine biosynthesis protein purh
UKS_RS00340	COG0151	Belongs to the GarS family
UKS_RS00345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
UKS_RS00360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
UKS_RS00365	COG3064	Membrane
UKS_RS00365	COG3583	domain protein
UKS_RS00365	COG3525	Glycosyl hydrolase, family 20, catalytic domain
UKS_RS00380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UKS_RS00385	COG3715	PTS system
UKS_RS00390	COG3716	PTS system mannose fructose sorbose family IID component
UKS_RS00400	COG2222	sugar isomerase
UKS_RS00415	COG2514	catechol 2,3-dioxygenase activity
UKS_RS00420	COG0110	maltose O-acetyltransferase activity
UKS_RS00425	COG1301	dicarboxylic acid transport
UKS_RS00440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
UKS_RS00445	COG0569	domain protein
UKS_RS00450	COG1215	transferase activity, transferring glycosyl groups
UKS_RS00465	COG5002	protein histidine kinase activity
UKS_RS00470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
UKS_RS00520	COG1396	sequence-specific DNA binding
UKS_RS00520	COG3800	Transcriptional regulator
UKS_RS00550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
UKS_RS00565	COG2151	metal-sulfur cluster biosynthetic enzyme
UKS_RS00585	COG0124	histidyl-tRNA synthetase
UKS_RS00595	COG1476	TRANSCRIPTIONal
UKS_RS00625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
UKS_RS00635	COG1609	Transcriptional regulator
UKS_RS00640	COG5521	maltodextrose utilization protein MalA
UKS_RS00645	COG3833	ABC-type maltose transport systems, permease component
UKS_RS00650	COG1175	transmembrane transport
UKS_RS00655	COG2182	Extracellular solute-binding protein
UKS_RS00660	COG1640	4-alpha-glucanotransferase
UKS_RS00665	COG0058	SHG alpha-glucan phosphorylase activity
UKS_RS00695	COG2226	methyltransferase
UKS_RS00705	COG2217	Heavy metal translocating P-type atpase
UKS_RS00715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UKS_RS00715	COG4499	WXG100 protein secretion system (Wss), protein YukC
UKS_RS00720	COG0697	spore germination
UKS_RS00735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
UKS_RS00745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
UKS_RS00760	COG0577	efflux transmembrane transporter activity
UKS_RS00760	COG1136	(ABC) transporter
UKS_RS00765	COG1136	(ABC) transporter
UKS_RS00765	COG0577	efflux transmembrane transporter activity
UKS_RS00790	COG1438	arginine binding
UKS_RS00800	COG1132	(ABC) transporter
UKS_RS00805	COG1132	(ABC) transporter
UKS_RS00810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
UKS_RS00820	COG0166	Belongs to the GPI family
UKS_RS00930	COG0534	Mate efflux family protein
UKS_RS00935	COG0546	phosphoglycolate phosphatase activity
UKS_RS00950	COG3759	membrane
UKS_RS00955	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
UKS_RS00980	COG1063	alcohol dehydrogenase
UKS_RS00990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UKS_RS00995	COG1459	type II secretion system
UKS_RS01000	COG4537	Required for transformation and DNA binding
UKS_RS01045	COG0706	membrane insertase activity
UKS_RS01060	COG3037	sugar-specific permease SgaT UlaA
UKS_RS01070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
UKS_RS01080	COG3623	hexulose-6-phosphate isomerase
UKS_RS01100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
UKS_RS01105	COG1862	Preprotein translocase
UKS_RS01110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
UKS_RS01120	COG1454	alcohol dehydrogenase
UKS_RS01120	COG1012	belongs to the aldehyde dehydrogenase family
UKS_RS01135	COG1136	(ABC) transporter
UKS_RS01140	COG0577	efflux transmembrane transporter activity
UKS_RS01160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UKS_RS01165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
UKS_RS01265	COG2176	DNA-directed DNA polymerase activity
UKS_RS01275	COG2309	aminopeptidase activity
UKS_RS01285	COG1187	pseudouridine synthase activity
UKS_RS01290	COG3579	cysteine-type endopeptidase activity
UKS_RS01295	COG3716	PTS system mannose fructose sorbose family IID component
UKS_RS01300	COG3715	PTS system
UKS_RS01310	COG1064	alcohol dehydrogenase
UKS_RS01315	COG0561	phosphatase activity
UKS_RS01320	COG2252	PERMEase
UKS_RS01330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
UKS_RS01335	COG0285	dihydrofolate synthase activity
UKS_RS01345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
UKS_RS01345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
UKS_RS01355	COG1609	Transcriptional regulator
UKS_RS01360	COG0252	asparaginase activity
UKS_RS01365	COG0561	phosphatase activity
UKS_RS01370	COG0589	response to stress
UKS_RS01380	COG0436	Aminotransferase
UKS_RS01390	COG4166	transmembrane transport
UKS_RS01400	COG0084	hydrolase, TatD family'
UKS_RS01415	COG1162	GTPase activity
UKS_RS01425	COG1564	THIamine pyrophosphokinase
UKS_RS01435	COG3481	metal-dependent phosphohydrolase, HD sub domain
UKS_RS01440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
UKS_RS01450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
UKS_RS01485	COG1254	Belongs to the acylphosphatase family
UKS_RS01490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UKS_RS01505	COG0742	ribosomal rna small subunit methyltransferase
UKS_RS01515	COG3480	Lon protease (S16) C-terminal proteolytic domain
UKS_RS01525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
UKS_RS01540	COG1253	flavin adenine dinucleotide binding
UKS_RS01550	COG4166	transmembrane transport
UKS_RS01555	COG0601	transmembrane transport
UKS_RS01560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UKS_RS01565	COG0444	Belongs to the ABC transporter superfamily
UKS_RS01570	COG4608	Belongs to the ABC transporter superfamily
UKS_RS01575	COG0583	DNA-binding transcription factor activity
UKS_RS01585	COG0281	malic enzyme
UKS_RS01605	COG4120	Belongs to the binding-protein-dependent transport system permease family
UKS_RS01610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
UKS_RS01640	COG0517	IMP dehydrogenase activity
UKS_RS01660	COG1187	pseudouridine synthase activity
UKS_RS01670	COG4607	ABC-type enterochelin transport system periplasmic component
UKS_RS01675	COG4604	ABC transporter, ATP-binding protein
UKS_RS01680	COG4605	iron ion homeostasis
UKS_RS01685	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UKS_RS01690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
UKS_RS01695	COG1363	Peptidase, m42
UKS_RS01710	COG3525	Glycosyl hydrolase, family 20, catalytic domain
UKS_RS01710	COG3583	domain protein
UKS_RS01710	COG3064	Membrane
UKS_RS01715	COG0126	phosphoglycerate kinase activity
UKS_RS01725	COG0789	Transcriptional regulator
UKS_RS01730	COG0174	glutamine synthetase
UKS_RS01755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UKS_RS01765	COG0484	heat shock protein binding
UKS_RS01775	COG0537	adenosine 5'-monophosphoramidase activity
UKS_RS01780	COG1131	(ABC) transporter
UKS_RS01785	COG4473	ABC transporter
UKS_RS01815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UKS_RS01820	COG2274	protein secretion by the type I secretion system
UKS_RS01855	COG1266	CAAX protease self-immunity
UKS_RS01880	COG0195	Participates in both transcription termination and antitermination
UKS_RS01885	COG2740	Nucleic-acid-binding protein implicated in transcription termination
UKS_RS01945	COG0519	Catalyzes the synthesis of GMP from XMP
UKS_RS01955	COG0525	valine-tRNA ligase activity
UKS_RS01970	COG0504	CTP synthase activity
UKS_RS01980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UKS_RS01985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UKS_RS01990	COG4221	oxidoreductase activity
UKS_RS02025	COG3231	kanamycin kinase activity
UKS_RS02030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
UKS_RS02145	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
UKS_RS02145	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
UKS_RS02150	COG2207	Transcriptional regulator
UKS_RS02155	COG3345	alpha-galactosidase
UKS_RS02160	COG1653	transport
UKS_RS02165	COG1175	transmembrane transport
UKS_RS02170	COG0395	ABC-type sugar transport system, permease component
UKS_RS02175	COG0366	Alpha amylase catalytic
UKS_RS02185	COG1846	Transcriptional regulator
UKS_RS02190	COG1125	glycine betaine transport
UKS_RS02190	COG0517	IMP dehydrogenase activity
UKS_RS02195	COG1174	glycine betaine transport
UKS_RS02205	COG1230	cation diffusion facilitator family transporter
UKS_RS02210	COG0789	Transcriptional regulator
UKS_RS02220	COG1609	Transcriptional regulator
UKS_RS02225	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
UKS_RS02240	COG2233	PERMEase
UKS_RS02255	COG0708	Exodeoxyribonuclease III
UKS_RS02270	COG1132	(ABC) transporter
UKS_RS02275	COG1132	(ABC) transporter
UKS_RS02280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UKS_RS02285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UKS_RS02290	COG0133	tryptophan synthase activity
UKS_RS02295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
UKS_RS02300	COG0512	Glutamine amidotransferase of anthranilate synthase
UKS_RS02325	COG0159	tryptophan synthase activity
UKS_RS02330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
UKS_RS02340	COG3237	CsbD-like
UKS_RS02360	COG2261	transglycosylase associated protein
UKS_RS02365	COG3711	transcriptional antiterminator
UKS_RS02370	COG1609	Transcriptional regulator
UKS_RS02380	COG1175	transmembrane transport
UKS_RS02385	COG0395	ABC-type sugar transport system, permease component
UKS_RS02390	COG1621	beta-fructofuranosidase activity
UKS_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
UKS_RS02405	COG0604	alcohol dehydrogenase
UKS_RS02405	COG3321	synthase
UKS_RS02410	COG1959	2 iron, 2 sulfur cluster binding
UKS_RS02420	COG0628	permease
UKS_RS02445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
UKS_RS02455	COG1051	belongs to the nudix hydrolase family
UKS_RS02465	COG2264	protein methyltransferase activity
UKS_RS02470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
UKS_RS02475	COG1164	Oligoendopeptidase f
UKS_RS02495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
UKS_RS02505	COG0720	synthase
UKS_RS02515	COG3118	belongs to the thioredoxin family
UKS_RS02535	COG1346	cytolysis
UKS_RS02545	COG1131	(ABC) transporter
UKS_RS02550	COG1725	Transcriptional regulator
UKS_RS02565	COG1484	DNA-dependent DNA replication
UKS_RS02590	COG0653	protein targeting
UKS_RS02595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UKS_RS02600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UKS_RS02615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
UKS_RS02635	COG1653	transport
UKS_RS02640	COG1175	transmembrane transport
UKS_RS02650	COG4409	exo-alpha-(2->6)-sialidase activity
UKS_RS02655	COG0673	inositol 2-dehydrogenase activity
UKS_RS02660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UKS_RS02685	COG0768	penicillin binding
UKS_RS02700	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
UKS_RS02720	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
UKS_RS02740	COG3599	regulation of cell shape
UKS_RS02745	COG3599	regulation of cell shape
UKS_RS02755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
UKS_RS02770	COG0577	efflux transmembrane transporter activity
UKS_RS02770	COG1136	(ABC) transporter
UKS_RS02780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
UKS_RS02800	COG3590	peptidase
UKS_RS02805	COG1216	Glycosyl transferase, family 2
UKS_RS02805	COG1442	glycosyl transferase family 8
UKS_RS02820	COG1216	Glycosyl transferase, family 2
UKS_RS02820	COG1442	glycosyl transferase family 8
UKS_RS02875	COG0860	N-Acetylmuramoyl-L-alanine amidase
UKS_RS02875	COG2247	cell wall binding repeat
UKS_RS02920	COG1959	2 iron, 2 sulfur cluster binding
UKS_RS02930	COG0745	RESPONSE REGULATOR receiver
UKS_RS02935	COG5002	protein histidine kinase activity
UKS_RS02945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
UKS_RS02960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UKS_RS02980	COG0204	Acyl-transferase
UKS_RS02985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
UKS_RS02990	COG2384	SAM-dependent methyltransferase
UKS_RS02995	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
UKS_RS03000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UKS_RS03005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
UKS_RS03010	COG0463	Glycosyl transferase, family 2
UKS_RS03030	COG2824	Alkylphosphonate utilization operon protein PhnA
UKS_RS03050	COG0351	phosphomethylpyrimidine kinase
UKS_RS03055	COG4720	Psort location CytoplasmicMembrane, score
UKS_RS03060	COG0006	proline dipeptidase activity
UKS_RS03065	COG3442	glutamine amidotransferase
UKS_RS03070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
UKS_RS03080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UKS_RS03085	COG2223	nitrite transmembrane transporter activity
UKS_RS03090	COG0513	Belongs to the DEAD box helicase family
UKS_RS03095	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
UKS_RS03100	COG1335	isochorismatase
UKS_RS03115	COG0577	efflux transmembrane transporter activity
UKS_RS03120	COG1136	(ABC) transporter
UKS_RS03125	COG0577	efflux transmembrane transporter activity
UKS_RS03130	COG0745	RESPONSE REGULATOR receiver
UKS_RS03135	COG5002	protein histidine kinase activity
UKS_RS03140	COG0191	fructose-bisphosphate aldolase activity
UKS_RS03145	COG0596	Alpha beta hydrolase
UKS_RS03155	COG4555	ABC transporter
UKS_RS03180	COG3250	beta-galactosidase activity
UKS_RS03190	COG1242	4 iron, 4 sulfur cluster binding
UKS_RS03195	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
UKS_RS03205	COG0025	NhaP-type Na H and K H
UKS_RS03230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
UKS_RS03235	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
UKS_RS03255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UKS_RS03265	COG0647	UMP catabolic process
UKS_RS03275	COG1393	Belongs to the ArsC family
UKS_RS03285	COG0483	inositol monophosphate 1-phosphatase activity
UKS_RS03290	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
UKS_RS03290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
UKS_RS03295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
UKS_RS03300	COG0573	inorganic phosphate transmembrane transporter activity
UKS_RS03305	COG0581	inorganic phosphate transmembrane transporter activity
UKS_RS03310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
UKS_RS03315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
UKS_RS03320	COG0704	Plays a role in the regulation of phosphate uptake
UKS_RS03325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UKS_RS03330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UKS_RS03340	COG3527	Alpha-acetolactate decarboxylase
UKS_RS03355	COG3842	ATPase activity
UKS_RS03360	COG1177	transmembrane transport
UKS_RS03395	COG1131	(ABC) transporter
UKS_RS03405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
UKS_RS03430	COG0287	Prephenate dehydrogenase
UKS_RS03445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
UKS_RS03450	COG0077	Prephenate dehydratase
UKS_RS03460	COG3475	LICD family
UKS_RS03470	COG1215	transferase activity, transferring glycosyl groups
UKS_RS03500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UKS_RS03500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UKS_RS03505	COG1132	(ABC) transporter
UKS_RS03510	COG1132	(ABC) transporter
UKS_RS03515	COG0402	S-adenosylhomocysteine deaminase activity
UKS_RS03520	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
UKS_RS03525	COG0222	ribosome binding
UKS_RS03550	COG2130	NADP-dependent
UKS_RS03555	COG1309	transcriptional regulator
UKS_RS03560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
UKS_RS03565	COG0167	dihydroorotate dehydrogenase activity
UKS_RS03575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UKS_RS03580	COG0582	viral genome integration into host DNA
UKS_RS03675	COG4470	Protein conserved in bacteria
UKS_RS03680	COG0820	rRNA (adenine-C2-)-methyltransferase activity
UKS_RS03690	COG0488	(ABC) transporter
UKS_RS03735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UKS_RS03755	COG1131	(ABC) transporter
UKS_RS03805	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
UKS_RS03805	COG1328	CTP reductase activity
UKS_RS03815	COG4443	Transcriptional Coactivator p15 (PC4)
UKS_RS03820	COG1268	BioY protein
UKS_RS03840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UKS_RS03845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UKS_RS03850	COG1136	(ABC) transporter
UKS_RS03855	COG0577	efflux transmembrane transporter activity
UKS_RS03860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UKS_RS03860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UKS_RS03875	COG4989	oxidoreductase activity
UKS_RS03885	COG1028	Short-chain dehydrogenase reductase Sdr
UKS_RS03910	COG0745	RESPONSE REGULATOR receiver
UKS_RS03915	COG5002	protein histidine kinase activity
UKS_RS03930	COG1136	(ABC) transporter
UKS_RS03940	COG1199	ATP-dependent helicase activity
UKS_RS03940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
UKS_RS03945	COG0772	Belongs to the SEDS family
UKS_RS03950	COG0693	protein deglycase activity
UKS_RS03965	COG0187	DNA topoisomerase II activity
UKS_RS03970	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
UKS_RS03985	COG0542	response to heat
UKS_RS03990	COG4703	Protein of unknown function (DUF1797)
UKS_RS03995	COG0765	amino acid transport
UKS_RS04000	COG1126	abc transporter atp-binding protein
UKS_RS04005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
UKS_RS04010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
UKS_RS04035	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
UKS_RS04045	COG0813	purine-nucleoside phosphorylase activity
UKS_RS04075	COG2813	Specifically methylates the guanine in position
UKS_RS04080	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
UKS_RS04095	COG1744	ABC transporter substrate-binding protein PnrA-like
UKS_RS04100	COG3845	ABC transporter
UKS_RS04105	COG4603	Belongs to the binding-protein-dependent transport system permease family
UKS_RS04110	COG1079	Belongs to the binding-protein-dependent transport system permease family
UKS_RS04120	COG0187	DNA topoisomerase II activity
UKS_RS04140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
UKS_RS04145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
UKS_RS04150	COG4166	transmembrane transport
UKS_RS04170	COG0539	negative regulation of cytoplasmic translation
UKS_RS04175	COG1956	GAF domain-containing protein
UKS_RS04180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
UKS_RS04195	COG0719	Fe-S assembly protein
UKS_RS04200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
UKS_RS04210	COG0719	Fe-S assembly protein
UKS_RS04215	COG1686	Belongs to the peptidase S11 family
UKS_RS04220	COG0628	permease
UKS_RS04270	COG0583	DNA-binding transcription factor activity
UKS_RS04275	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
UKS_RS04280	COG0564	pseudouridine synthase activity
UKS_RS04285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UKS_RS04300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
UKS_RS04310	COG0470	DNA polymerase III
UKS_RS04330	COG0528	UMP kinase activity
UKS_RS04340	COG2996	Protein conserved in bacteria
UKS_RS04345	COG0456	acetyltransferase
UKS_RS04345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
UKS_RS04355	COG1702	phosphate starvation-inducible protein PhoH
UKS_RS04360	COG0686	Belongs to the AlaDH PNT family
UKS_RS04365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UKS_RS04370	COG1596	polysaccharide export
UKS_RS04370	COG1555	photosystem II stabilization
UKS_RS04375	COG2333	competence protein COMEC
UKS_RS04375	COG0658	competence protein
UKS_RS04385	COG1131	(ABC) transporter
UKS_RS04405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
UKS_RS04420	COG0543	2 iron, 2 sulfur cluster binding
UKS_RS04425	COG0167	dihydroorotate dehydrogenase activity
UKS_RS04435	COG1293	RNA-binding protein homologous to eukaryotic snRNP
UKS_RS04445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
UKS_RS04455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
UKS_RS04460	COG0237	dephospho-CoA kinase activity
UKS_RS04465	COG2814	Major facilitator Superfamily
UKS_RS04470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
UKS_RS04480	COG0557	exoribonuclease II activity
UKS_RS04490	COG0500	methyltransferase
UKS_RS04490	COG3615	Tellurite resistance protein tehB
UKS_RS04515	COG4122	O-methyltransferase activity
UKS_RS04530	COG0772	Belongs to the SEDS family
UKS_RS04535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
UKS_RS04555	COG0358	DNA primase activity
UKS_RS04560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UKS_RS04565	COG2151	metal-sulfur cluster biosynthetic enzyme
UKS_RS04570	COG0438	transferase activity, transferring glycosyl groups
UKS_RS04575	COG0438	transferase activity, transferring glycosyl groups
UKS_RS04600	COG1438	arginine binding
UKS_RS04605	COG2936	dipeptidyl-peptidase activity
UKS_RS04625	COG0469	pyruvate kinase activity
UKS_RS04640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
UKS_RS04645	COG3764	Sortase (surface protein transpeptidase)
UKS_RS04665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
UKS_RS04695	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
UKS_RS04700	COG1438	arginine binding
UKS_RS04705	COG0497	DNA recombination
UKS_RS04710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
UKS_RS04730	COG3775	system Galactitol-specific IIC component
UKS_RS04755	COG3684	Belongs to the aldolase LacD family
UKS_RS04775	COG0463	Glycosyl transferase, family 2
UKS_RS04780	COG3711	transcriptional antiterminator
UKS_RS04795	COG2723	6-phospho-beta-galactosidase activity
UKS_RS04810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UKS_RS04815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UKS_RS04820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
UKS_RS04825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UKS_RS04850	COG2376	Dihydroxyacetone kinase
UKS_RS04855	COG1309	transcriptional regulator
UKS_RS04860	COG2376	Dihydroxyacetone kinase
UKS_RS04865	COG1461	Dihydroxyacetone kinase
UKS_RS04870	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
UKS_RS04885	COG1136	(ABC) transporter
UKS_RS04885	COG0577	efflux transmembrane transporter activity
UKS_RS04890	COG1011	Hydrolase
UKS_RS04900	COG1051	belongs to the nudix hydrolase family
UKS_RS04905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
UKS_RS04910	COG0534	Mate efflux family protein
UKS_RS04915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
UKS_RS04920	COG0022	dehydrogenase e1 component
UKS_RS04925	COG0508	dehydrogenase complex catalyzes the overall conversion of
UKS_RS04930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UKS_RS04935	COG0095	Lipoate-protein ligase
UKS_RS04960	COG0038	chloride channel
UKS_RS04970	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
UKS_RS05000	COG0561	phosphatase activity
UKS_RS05005	COG1131	(ABC) transporter
UKS_RS05015	COG2205	protein histidine kinase activity
UKS_RS05020	COG0745	RESPONSE REGULATOR receiver
UKS_RS05025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UKS_RS05045	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
UKS_RS05050	COG1982	Orn Lys Arg decarboxylase major
UKS_RS05065	COG0577	efflux transmembrane transporter activity
UKS_RS05070	COG1136	(ABC) transporter
UKS_RS05085	COG2183	response to ionizing radiation
UKS_RS05095	COG0701	Predicted permease
UKS_RS05100	COG3689	TIGRFAM TIGR03943 family protein
UKS_RS05135	COG1597	lipid kinase activity
UKS_RS05150	COG2217	Heavy metal translocating P-type atpase
UKS_RS05155	COG0640	Transcriptional regulator
UKS_RS05180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
UKS_RS05190	COG0741	lytic transglycosylase activity
UKS_RS05215	COG2890	protein-(glutamine-N5) methyltransferase activity
UKS_RS05220	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
UKS_RS05225	COG1435	thymidine kinase activity
UKS_RS05230	COG1942	4-Oxalocrotonate Tautomerase
UKS_RS05235	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
UKS_RS05245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UKS_RS05255	COG4708	membrane
UKS_RS05275	COG2195	Cleaves the N-terminal amino acid of tripeptides
UKS_RS05290	COG0803	Belongs to the bacterial solute-binding protein 9 family
UKS_RS05290	COG3443	Belongs to the bacterial solute-binding protein 9 family
UKS_RS05295	COG0531	amino acid
UKS_RS05300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UKS_RS05305	COG0785	Cytochrome C biogenesis protein
UKS_RS05320	COG5632	N-Acetylmuramoyl-L-alanine amidase
UKS_RS05320	COG5263	repeat protein
UKS_RS05380	COG3299	homolog of phage Mu protein gp47
UKS_RS05565	COG0629	single-stranded DNA binding
UKS_RS05680	COG0582	viral genome integration into host DNA
UKS_RS05690	COG1307	EDD domain protein, DegV family
UKS_RS05695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
UKS_RS05700	COG0196	riboflavin kinase activity
UKS_RS05705	COG0024	Methionine aminopeptidase
UKS_RS05710	COG4109	DRTGG domain
UKS_RS05720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
UKS_RS05740	COG0560	Phosphoserine phosphatase
UKS_RS05750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
UKS_RS05760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
UKS_RS05765	COG1523	belongs to the glycosyl hydrolase 13 family
UKS_RS05785	COG0488	(ABC) transporter
UKS_RS05790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
UKS_RS05800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
UKS_RS05810	COG0745	RESPONSE REGULATOR receiver
UKS_RS05815	COG1194	a g-specific adenine glycosylase
UKS_RS05820	COG0280	phosphate acetyltransferase
UKS_RS05825	COG0564	pseudouridine synthase activity
UKS_RS05835	COG2357	RelA SpoT domain protein
UKS_RS05845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
UKS_RS05850	COG1104	cysteine desulfurase activity
UKS_RS05870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
UKS_RS05890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
UKS_RS05895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
UKS_RS05900	COG4684	Psort location CytoplasmicMembrane, score
UKS_RS05910	COG1827	regulation of RNA biosynthetic process
UKS_RS05920	COG1879	ABC-type sugar transport system periplasmic component
UKS_RS05925	COG1172	Belongs to the binding-protein-dependent transport system permease family
UKS_RS05935	COG1869	D-ribose catabolic process
UKS_RS05940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UKS_RS05945	COG1609	Transcriptional regulator
UKS_RS05955	COG2816	NAD+ diphosphatase activity
UKS_RS05965	COG0556	nucleotide-excision repair
UKS_RS05975	COG0765	amino acid transport
UKS_RS05980	COG1126	abc transporter atp-binding protein
UKS_RS05985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
UKS_RS05990	COG0552	protein localization to endoplasmic reticulum
UKS_RS05995	COG0561	phosphatase activity
UKS_RS06000	COG0561	phosphatase activity
UKS_RS06005	COG1196	nuclear chromosome segregation
UKS_RS06030	COG0066	3-isopropylmalate dehydratase activity
UKS_RS06045	COG0473	3-isopropylmalate dehydrogenase activity
UKS_RS06060	COG3142	Participates in the control of copper homeostasis
UKS_RS06065	COG2832	Protein of unknown function (DUF454)
UKS_RS06070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UKS_RS06075	COG0758	DNA mediated transformation
UKS_RS06080	COG4750	Nucleotidyl transferase
UKS_RS06095	COG1063	alcohol dehydrogenase
UKS_RS06110	COG3475	LICD family
UKS_RS06115	COG3475	LICD family
UKS_RS06125	COG1914	H( )-stimulated, divalent metal cation uptake system
UKS_RS06135	COG0505	Belongs to the CarA family
UKS_RS06150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
UKS_RS06165	COG0488	(ABC) transporter
UKS_RS06170	COG0501	Belongs to the peptidase M48B family
UKS_RS06175	COG1704	LemA family
UKS_RS06190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
UKS_RS06205	COG1078	dGTPase activity
UKS_RS06260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
UKS_RS06265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
UKS_RS06270	COG0077	Prephenate dehydratase
UKS_RS06270	COG1605	Chorismate mutase
UKS_RS06275	COG0716	FMN binding
UKS_RS06280	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
UKS_RS06320	COG1674	ftsk spoiiie
UKS_RS06340	COG0582	viral genome integration into host DNA
UKS_RS06350	COG0584	glycerophosphoryl diester phosphodiesterase
UKS_RS06355	COG2176	DNA-directed DNA polymerase activity
UKS_RS06365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
UKS_RS06375	COG0494	nUDIX hydrolase
UKS_RS06380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
UKS_RS06395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
UKS_RS06415	COG1126	abc transporter atp-binding protein
UKS_RS06430	COG0628	permease
UKS_RS06435	COG4166	transmembrane transport
UKS_RS06440	COG2706	6-phosphogluconolactonase activity
UKS_RS06485	COG0826	peptidase U32
UKS_RS06495	COG2188	Transcriptional regulator
UKS_RS06500	COG0697	spore germination
UKS_RS06505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
UKS_RS06525	COG1136	(ABC) transporter
UKS_RS06525	COG0577	efflux transmembrane transporter activity
UKS_RS06540	COG2826	transposase and inactivated derivatives, IS30 family
UKS_RS06565	COG1104	cysteine desulfurase activity
UKS_RS06575	COG1136	(ABC) transporter
UKS_RS06585	COG1674	ftsk spoiiie
UKS_RS06585	COG0697	spore germination
UKS_RS06590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
UKS_RS06590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
UKS_RS06590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
UKS_RS06595	COG1105	Belongs to the carbohydrate kinase PfkB family
UKS_RS06600	COG1349	DNA-binding transcription factor activity
UKS_RS06620	COG0561	phosphatase activity
UKS_RS06640	COG0492	ferredoxin-NADP+ reductase activity
UKS_RS06650	COG1126	abc transporter atp-binding protein
UKS_RS06660	COG1393	Belongs to the ArsC family
UKS_RS06665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
UKS_RS06680	COG1272	protein, Hemolysin III
UKS_RS06710	COG3976	FMN-binding domain protein
UKS_RS06710	COG1053	succinate dehydrogenase
UKS_RS06710	COG0431	NADPH-dependent FMN reductase
UKS_RS06720	COG0751	glycine-tRNA ligase activity
UKS_RS06730	COG0656	L-ascorbic acid biosynthetic process
UKS_RS06735	COG0726	polysaccharide deacetylase
UKS_RS06750	COG0513	Belongs to the DEAD box helicase family
UKS_RS06760	COG2190	(PTS) system
UKS_RS06760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UKS_RS06760	COG1263	PTS System
UKS_RS06765	COG2177	Part of the ABC transporter FtsEX involved in
UKS_RS06770	COG2884	Cell division ATP-binding protein ftsE
UKS_RS06790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
UKS_RS06790	COG0617	tRNA 3'-terminal CCA addition
UKS_RS06790	COG0517	IMP dehydrogenase activity
UKS_RS06825	COG0740	serine-type endopeptidase activity
UKS_RS06830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
UKS_RS06835	COG2131	deaminase
UKS_RS06845	COG1307	EDD domain protein, DegV family
UKS_RS06850	COG2081	HI0933 family
UKS_RS06860	COG0789	Transcriptional regulator
UKS_RS06865	COG0733	neurotransmitter:sodium symporter activity
UKS_RS06870	COG1482	cell wall glycoprotein biosynthetic process
UKS_RS06875	COG2723	6-phospho-beta-galactosidase activity
UKS_RS06885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
UKS_RS06900	COG0028	Belongs to the TPP enzyme family
UKS_RS06905	COG2217	Heavy metal translocating P-type atpase
UKS_RS06925	COG0352	thiamine-phosphate diphosphorylase activity
UKS_RS06940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
UKS_RS06950	COG4172	Belongs to the ABC transporter superfamily
UKS_RS06965	COG1304	FMN binding
UKS_RS06980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
UKS_RS06995	COG1136	(ABC) transporter
UKS_RS07010	COG1217	gtp-binding protein TYPA
UKS_RS07015	COG1187	pseudouridine synthase activity
UKS_RS07035	COG0300	oxidoreductase activity
UKS_RS07050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
UKS_RS07055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
UKS_RS07070	COG1940	carbohydrate kinase activity
UKS_RS07085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
UKS_RS07090	COG3064	Membrane
UKS_RS07100	COG2972	Histidine kinase
UKS_RS07105	COG2207	Transcriptional regulator
UKS_RS07105	COG4753	response regulator
UKS_RS07110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UKS_RS07110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UKS_RS07115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UKS_RS07120	COG0785	Cytochrome C biogenesis protein
UKS_RS07125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UKS_RS07135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
UKS_RS07145	COG1113	amino acid transport
UKS_RS07155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
UKS_RS07185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UKS_RS07190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
UKS_RS07195	COG0626	cystathionine gamma-synthase activity
UKS_RS07205	COG4166	transmembrane transport
UKS_RS07210	COG2244	polysaccharide biosynthetic process
UKS_RS07215	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
UKS_RS07220	COG3237	CsbD-like
UKS_RS07240	COG2827	Endonuclease containing a URI domain
UKS_RS07245	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
UKS_RS07250	COG1098	S1 RNA binding domain
UKS_RS07265	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
UKS_RS07270	COG0629	single-stranded DNA binding
UKS_RS07280	COG0017	Asparaginyl-tRNA synthetase
UKS_RS07285	COG0436	Aminotransferase
UKS_RS07315	COG0242	peptide deformylase activity
UKS_RS07320	COG0625	glutathione transferase activity
UKS_RS07330	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
UKS_RS07335	COG0488	(ABC) transporter
UKS_RS07340	COG0617	tRNA 3'-terminal CCA addition
UKS_RS07350	COG1307	EDD domain protein, DegV family
UKS_RS07370	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
UKS_RS07375	COG0492	ferredoxin-NADP+ reductase activity
UKS_RS07385	COG0391	Required for morphogenesis under gluconeogenic growth conditions
UKS_RS07395	COG0251	oxidation-reduction process
UKS_RS07415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
UKS_RS07425	COG4193	domain, Protein
UKS_RS07425	COG5263	repeat protein
UKS_RS07435	COG3935	DnaD domain protein
UKS_RS07470	COG1363	Peptidase, m42
UKS_RS07475	COG1114	Component of the transport system for branched-chain amino acids
UKS_RS07485	COG1573	uracil-dna glycosylase
UKS_RS07535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
UKS_RS07535	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
UKS_RS07545	COG3842	ATPase activity
UKS_RS07555	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
UKS_RS07560	COG0215	cysteine-tRNA ligase activity
UKS_RS07570	COG1045	serine acetyltransferase
UKS_RS07585	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
UKS_RS07615	COG1940	carbohydrate kinase activity
UKS_RS07620	COG1263	PTS System
UKS_RS07620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UKS_RS07620	COG2190	(PTS) system
UKS_RS07625	COG1621	beta-fructofuranosidase activity
UKS_RS07630	COG1609	Transcriptional regulator
UKS_RS07640	COG3425	synthase
UKS_RS07655	COG0515	serine threonine protein kinase
UKS_RS07655	COG2815	serine threonine protein kinase
UKS_RS07660	COG0631	protein serine/threonine phosphatase activity
UKS_RS07665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
UKS_RS07665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UKS_RS07675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
UKS_RS07685	COG0194	GDP metabolic process
UKS_RS07695	COG4115	mRNA cleavage
UKS_RS07715	COG2226	methyltransferase
UKS_RS07720	COG0799	negative regulation of ribosome biogenesis
UKS_RS07730	COG1713	HD superfamily hydrolase involved in NAD metabolism
UKS_RS07735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
UKS_RS07740	COG1534	Rna-binding protein
UKS_RS07745	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
UKS_RS07750	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
UKS_RS07760	COG0668	transmembrane transport
UKS_RS07765	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
UKS_RS07780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
UKS_RS07830	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
UKS_RS07835	COG0439	Biotin carboxylase
UKS_RS07850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UKS_RS07855	COG1028	Short-chain dehydrogenase reductase Sdr
UKS_RS07860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
UKS_RS07870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UKS_RS07880	COG1846	Transcriptional regulator
UKS_RS07885	COG1024	Enoyl-CoA hydratase
UKS_RS07890	COG0527	aspartate kinase activity
UKS_RS07920	COG1115	amino acid carrier protein
UKS_RS07945	COG0681	Belongs to the peptidase S26 family
UKS_RS07950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
UKS_RS07970	COG2197	response regulator
UKS_RS07975	COG4585	Histidine kinase
UKS_RS08010	COG0745	RESPONSE REGULATOR receiver
UKS_RS08015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
UKS_RS08025	COG0116	Belongs to the methyltransferase superfamily
UKS_RS08055	COG4166	transmembrane transport
UKS_RS08060	COG1091	dTDP-4-dehydrorhamnose reductase activity
UKS_RS08065	COG1088	dTDP-glucose 4,6-dehydratase activity
UKS_RS08075	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
UKS_RS08080	COG0562	UDP-galactopyranose mutase
UKS_RS08085	COG4166	transmembrane transport
UKS_RS08090	COG4166	transmembrane transport
UKS_RS08095	COG0366	Alpha amylase catalytic
UKS_RS08120	COG0768	penicillin binding
UKS_RS08125	COG4839	cell division protein FtsL
UKS_RS08155	COG0386	Belongs to the glutathione peroxidase family
UKS_RS08160	COG3583	domain protein
UKS_RS08160	COG3525	Glycosyl hydrolase, family 20, catalytic domain
UKS_RS08160	COG3064	Membrane
UKS_RS08170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
UKS_RS08190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
UKS_RS08195	COG3620	sequence-specific DNA binding
UKS_RS08215	COG1653	transport
UKS_RS08220	COG0395	ABC-type sugar transport system, permease component
UKS_RS08225	COG4209	transmembrane transport
UKS_RS08235	COG2169	Transcriptional regulator
UKS_RS08245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UKS_RS08250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
UKS_RS08255	COG1668	transmembrane transport
UKS_RS08260	COG4152	abc transporter atp-binding protein
UKS_RS08270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UKS_RS08270	COG0072	phenylalanine-tRNA ligase activity
UKS_RS08275	COG0456	acetyltransferase
UKS_RS08285	COG0671	phosphoesterase, PA-phosphatase related
UKS_RS08290	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
UKS_RS08305	COG1122	ATPase activity
UKS_RS08320	COG0569	domain protein
UKS_RS08325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
UKS_RS08330	COG1882	Formate acetyltransferase
UKS_RS08335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
UKS_RS08350	COG0765	amino acid transport
UKS_RS08365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
UKS_RS08375	COG0440	acetolactate synthase activity
UKS_RS08380	COG0028	Belongs to the TPP enzyme family
UKS_RS08405	COG2197	response regulator
UKS_RS08410	COG4585	Histidine kinase
UKS_RS08420	COG1131	(ABC) transporter
UKS_RS08435	COG1461	Dihydroxyacetone kinase
UKS_RS08445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
UKS_RS08495	COG0534	Mate efflux family protein
UKS_RS08520	COG1316	TRANSCRIPTIONal
UKS_RS08530	COG0802	atpase or kinase
UKS_RS08560	COG1523	belongs to the glycosyl hydrolase 13 family
UKS_RS08570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
UKS_RS08575	COG2723	6-phospho-beta-galactosidase activity
UKS_RS08585	COG0750	zinc metalloprotease
UKS_RS08590	COG4589	Belongs to the CDS family
UKS_RS08595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
UKS_RS08605	COG2255	four-way junction helicase activity
UKS_RS08625	COG2972	Histidine kinase
UKS_RS08630	COG2207	Transcriptional regulator
UKS_RS08630	COG4753	response regulator
UKS_RS08635	COG1840	ABC-type Fe3 transport system, periplasmic component
UKS_RS08640	COG1840	ABC-type Fe3 transport system, periplasmic component
UKS_RS08645	COG3842	ATPase activity
UKS_RS08650	COG1178	ABC-type Fe3 transport system permease component
UKS_RS08660	COG2848	UPF0210 protein
UKS_RS08665	COG3830	Belongs to the UPF0237 family
UKS_RS08675	COG0202	RNA polymerase activity
UKS_RS08680	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
UKS_RS08690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
UKS_RS08695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
UKS_RS08705	COG0201	protein transport
UKS_RS08720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
UKS_RS08740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
UKS_RS08760	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
UKS_RS08785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
UKS_RS08815	COG0602	queuosine metabolic process
UKS_RS08830	COG1328	CTP reductase activity
UKS_RS08845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UKS_RS08855	COG0285	dihydrofolate synthase activity
UKS_RS08880	COG1393	Belongs to the ArsC family
UKS_RS08885	COG0006	proline dipeptidase activity
UKS_RS08890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
UKS_RS08920	COG0519	Catalyzes the synthesis of GMP from XMP
UKS_RS08950	COG1780	Probably involved in ribonucleotide reductase function
UKS_RS08960	COG2207	Transcriptional regulator
UKS_RS08960	COG4753	response regulator
UKS_RS08965	COG2972	Histidine kinase
UKS_RS08990	COG2197	response regulator
UKS_RS09005	COG1136	(ABC) transporter
UKS_RS09040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
UKS_RS09045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UKS_RS09050	COG1464	Belongs to the NlpA lipoprotein family
UKS_RS09055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UKS_RS09095	COG1396	sequence-specific DNA binding
UKS_RS09100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
UKS_RS09110	COG1214	PFAM Peptidase M22, glycoprotease
UKS_RS09135	COG0445	tRNA wobble uridine modification
UKS_RS09140	COG0494	nUDIX hydrolase
UKS_RS09155	COG1136	(ABC) transporter
UKS_RS09155	COG0577	efflux transmembrane transporter activity
UKS_RS09175	COG1705	Flagellar rod assembly protein muramidase FlgJ
UKS_RS09175	COG1388	LysM domain
UKS_RS09180	COG1760	l-serine dehydratase
UKS_RS09185	COG1760	l-serine dehydratase
UKS_RS09200	COG1216	Glycosyl transferase, family 2
UKS_RS09210	COG1695	Transcriptional regulator
UKS_RS09240	COG1653	transport
UKS_RS09245	COG0395	ABC-type sugar transport system, permease component
UKS_RS09250	COG4209	transmembrane transport
UKS_RS09265	COG0383	alpha-mannosidase activity
UKS_RS09275	COG3537	Alpha-1,2-mannosidase
UKS_RS09305	COG0549	Belongs to the carbamate kinase family
UKS_RS09310	COG1288	antiporter activity
UKS_RS09330	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
UKS_RS09335	COG0803	Belongs to the bacterial solute-binding protein 9 family
UKS_RS09335	COG3443	Belongs to the bacterial solute-binding protein 9 family
UKS_RS09340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UKS_RS09345	COG1121	(ABC) transporter
UKS_RS09350	COG1846	Transcriptional regulator
UKS_RS09355	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
UKS_RS09365	COG1696	Membrane protein involved in D-alanine export
UKS_RS09385	COG2211	Major facilitator Superfamily
UKS_RS09390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
UKS_RS09395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
UKS_RS09415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UKS_RS09420	COG1335	isochorismatase
UKS_RS09440	COG3201	nicotinamide mononucleotide transporter
UKS_RS09445	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
UKS_RS09450	COG0542	response to heat
UKS_RS09455	COG4463	regulation of RNA biosynthetic process
UKS_RS09460	COG1116	anion transmembrane transporter activity
UKS_RS09465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UKS_RS09470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UKS_RS09490	COG0305	Participates in initiation and elongation during chromosome replication
UKS_RS09510	COG1040	competence protein
UKS_RS09515	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
UKS_RS09520	COG1739	Uncharacterized protein family UPF0029
UKS_RS09550	COG3942	CHAP domain
UKS_RS09560	COG1792	Involved in formation and maintenance of cell shape
UKS_RS09565	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
UKS_RS09570	COG1122	ATPase activity
UKS_RS09575	COG1122	ATPase activity
UKS_RS09580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UKS_RS09590	COG0612	Peptidase, M16
UKS_RS09595	COG0612	Peptidase, M16
UKS_RS09600	COG2501	S4 domain
UKS_RS09610	COG0516	GMP reductase activity
UKS_RS09610	COG0517	IMP dehydrogenase activity
UKS_RS09615	COG0180	Tryptophanyl-tRNA synthetase
UKS_RS09620	COG0488	(ABC) transporter
UKS_RS09630	COG1511	domain protein
UKS_RS09630	COG1511	domain protein
UKS_RS09675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UKS_RS09680	COG1475	DNA binding