locus-tag	class	description
GP482_RS00060	COG1012	belongs to the aldehyde dehydrogenase family
GP482_RS00060	COG1454	alcohol dehydrogenase
GP482_RS00070	COG1185	polyribonucleotide nucleotidyltransferase activity
GP482_RS00080	COG1045	serine acetyltransferase
GP482_RS00090	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GP482_RS00125	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GP482_RS00165	COG3830	Belongs to the UPF0237 family
GP482_RS00175	COG0588	phosphoglycerate mutase activity
GP482_RS00180	COG1876	peptidase activity
GP482_RS00185	COG1705	Flagellar rod assembly protein muramidase FlgJ
GP482_RS00235	COG4475	Protein of unknown function (DUF436)
GP482_RS00240	COG0668	transmembrane transport
GP482_RS00255	COG0504	CTP synthase activity
GP482_RS00280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GP482_RS00290	COG1461	Dihydroxyacetone kinase
GP482_RS00295	COG0129	dihydroxy-acid dehydratase activity
GP482_RS00300	COG0028	Belongs to the TPP enzyme family
GP482_RS00305	COG0440	acetolactate synthase activity
GP482_RS00315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GP482_RS00330	COG1126	abc transporter atp-binding protein
GP482_RS00335	COG0765	amino acid transport
GP482_RS00350	COG4862	establishment of competence for transformation
GP482_RS00355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GP482_RS00365	COG0719	Fe-S assembly protein
GP482_RS00370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GP482_RS00380	COG0719	Fe-S assembly protein
GP482_RS00385	COG1686	Belongs to the peptidase S11 family
GP482_RS00390	COG4166	transmembrane transport
GP482_RS00395	COG0601	transmembrane transport
GP482_RS00400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GP482_RS00405	COG0444	Belongs to the ABC transporter superfamily
GP482_RS00410	COG4608	Belongs to the ABC transporter superfamily
GP482_RS00445	COG0527	aspartate kinase activity
GP482_RS00450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GP482_RS00455	COG1024	Enoyl-CoA hydratase
GP482_RS00465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GP482_RS00480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GP482_RS00485	COG1028	Short-chain dehydrogenase reductase Sdr
GP482_RS00490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GP482_RS00505	COG0439	Biotin carboxylase
GP482_RS00530	COG3716	PTS system mannose fructose sorbose family IID component
GP482_RS00535	COG3715	PTS system
GP482_RS00545	COG0561	phosphatase activity
GP482_RS00560	COG2252	PERMEase
GP482_RS00565	COG0802	atpase or kinase
GP482_RS00575	COG1316	TRANSCRIPTIONal
GP482_RS00585	COG0537	adenosine 5'-monophosphoramidase activity
GP482_RS00590	COG1131	(ABC) transporter
GP482_RS00595	COG4473	ABC transporter
GP482_RS00605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GP482_RS00615	COG5001	Diguanylate cyclase
GP482_RS00615	COG3300	MHYT domain
GP482_RS00620	COG0463	Glycosyl transferase, family 2
GP482_RS00640	COG0195	Participates in both transcription termination and antitermination
GP482_RS00645	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GP482_RS00655	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GP482_RS00660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GP482_RS00665	COG1131	(ABC) transporter
GP482_RS00685	COG1611	Belongs to the LOG family
GP482_RS00700	COG2217	Heavy metal translocating P-type atpase
GP482_RS00710	COG2860	membrane
GP482_RS00715	COG0561	phosphatase activity
GP482_RS00740	COG1283	sodium-dependent phosphate transmembrane transporter activity
GP482_RS00760	COG4224	UPF0291 protein
GP482_RS00775	COG1131	(ABC) transporter
GP482_RS00795	COG0275	rRNA processing
GP482_RS00805	COG0768	penicillin binding
GP482_RS00810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GP482_RS00815	COG0513	Belongs to the DEAD box helicase family
GP482_RS00830	COG1126	abc transporter atp-binding protein
GP482_RS00840	COG0492	ferredoxin-NADP+ reductase activity
GP482_RS00845	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GP482_RS00855	COG3579	cysteine-type endopeptidase activity
GP482_RS00860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GP482_RS00865	COG3331	DNA recombination
GP482_RS00870	COG4474	Belongs to the UPF0398 family
GP482_RS00875	COG3599	regulation of cell shape
GP482_RS00885	COG0116	Belongs to the methyltransferase superfamily
GP482_RS00900	COG1854	S-ribosylhomocysteine lyase activity
GP482_RS00920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GP482_RS00930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GP482_RS00930	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GP482_RS00940	COG2815	serine threonine protein kinase
GP482_RS00940	COG0515	serine threonine protein kinase
GP482_RS00950	COG4585	Histidine kinase
GP482_RS00955	COG2197	response regulator
GP482_RS00965	COG1098	S1 RNA binding domain
GP482_RS00975	COG1739	Uncharacterized protein family UPF0029
GP482_RS00980	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GP482_RS00985	COG1040	competence protein
GP482_RS01055	COG3557	Belongs to the UPF0374 family
GP482_RS01060	COG2137	regulation of response to DNA damage stimulus
GP482_RS01070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GP482_RS01090	COG1428	Deoxynucleoside kinase
GP482_RS01110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GP482_RS01120	COG1396	sequence-specific DNA binding
GP482_RS01135	COG4716	Myosin-crossreactive antigen
GP482_RS01165	COG0742	ribosomal rna small subunit methyltransferase
GP482_RS01170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GP482_RS01175	COG3480	Lon protease (S16) C-terminal proteolytic domain
GP482_RS01185	COG0737	Belongs to the 5'-nucleotidase family
GP482_RS01190	COG4470	Protein conserved in bacteria
GP482_RS01205	COG1132	(ABC) transporter
GP482_RS01210	COG1132	(ABC) transporter
GP482_RS01215	COG1131	(ABC) transporter
GP482_RS01225	COG4585	Histidine kinase
GP482_RS01230	COG2197	response regulator
GP482_RS01240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GP482_RS01245	COG0512	Glutamine amidotransferase of anthranilate synthase
GP482_RS01260	COG0135	phosphoribosylanthranilate isomerase activity
GP482_RS01265	COG0133	tryptophan synthase activity
GP482_RS01270	COG0159	tryptophan synthase activity
GP482_RS01275	COG1914	H( )-stimulated, divalent metal cation uptake system
GP482_RS01285	COG0783	Belongs to the Dps family
GP482_RS01295	COG1940	carbohydrate kinase activity
GP482_RS01300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GP482_RS01340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GP482_RS01345	COG1799	cell septum assembly
GP482_RS01360	COG3599	regulation of cell shape
GP482_RS01380	COG0542	response to heat
GP482_RS01395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GP482_RS01400	COG4703	Protein of unknown function (DUF1797)
GP482_RS01405	COG0765	amino acid transport
GP482_RS01410	COG1126	abc transporter atp-binding protein
GP482_RS01420	COG1918	ferrous iron import across plasma membrane
GP482_RS01420	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GP482_RS01435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GP482_RS01470	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GP482_RS01475	COG1438	arginine binding
GP482_RS01480	COG0497	DNA recombination
GP482_RS01485	COG1307	EDD domain protein, DegV family
GP482_RS01490	COG2755	lipolytic protein G-D-S-L family
GP482_RS01495	COG4698	Protein conserved in bacteria
GP482_RS01515	COG0167	dihydroorotate dehydrogenase activity
GP482_RS01520	COG0640	Transcriptional regulator
GP482_RS01525	COG2217	Heavy metal translocating P-type atpase
GP482_RS01535	COG1827	regulation of RNA biosynthetic process
GP482_RS01545	COG0768	penicillin binding
GP482_RS01550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GP482_RS01555	COG1181	Belongs to the D-alanine--D-alanine ligase family
GP482_RS01565	COG0385	Bile acid
GP482_RS01570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GP482_RS01585	COG0513	Belongs to the DEAD box helicase family
GP482_RS01595	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GP482_RS01600	COG0204	Acyl-transferase
GP482_RS01605	COG1555	photosystem II stabilization
GP482_RS01605	COG1596	polysaccharide export
GP482_RS01610	COG0658	competence protein
GP482_RS01610	COG2333	competence protein COMEC
GP482_RS01625	COG1466	dna polymerase III delta subunit
GP482_RS01630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GP482_RS01635	COG0217	transcriptional regulatory protein
GP482_RS01640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GP482_RS01655	COG1187	pseudouridine synthase activity
GP482_RS01675	COG0546	phosphoglycolate phosphatase activity
GP482_RS01685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GP482_RS01690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GP482_RS01700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GP482_RS01705	COG0436	Aminotransferase
GP482_RS01715	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GP482_RS01720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GP482_RS01725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GP482_RS01735	COG1476	TRANSCRIPTIONal
GP482_RS01745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GP482_RS01745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GP482_RS01750	COG0307	riboflavin synthase, alpha
GP482_RS01755	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GP482_RS01755	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GP482_RS01765	COG3859	Proton-coupled thiamine transporter YuaJ
GP482_RS01775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GP482_RS01780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GP482_RS01785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GP482_RS01790	COG0372	Belongs to the citrate synthase family
GP482_RS01820	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GP482_RS01830	COG0513	Belongs to the DEAD box helicase family
GP482_RS01855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GP482_RS01860	COG0066	3-isopropylmalate dehydratase activity
GP482_RS01865	COG1956	GAF domain-containing protein
GP482_RS01870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GP482_RS01880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GP482_RS01880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GP482_RS01885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GP482_RS01890	COG2207	Transcriptional regulator
GP482_RS01890	COG3708	Transcriptional regulator
GP482_RS01895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GP482_RS01900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GP482_RS01905	COG4109	DRTGG domain
GP482_RS01910	COG0024	Methionine aminopeptidase
GP482_RS01920	COG2246	polysaccharide biosynthetic process
GP482_RS01925	COG4708	membrane
GP482_RS01930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GP482_RS01935	COG1597	lipid kinase activity
GP482_RS01985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GP482_RS02015	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GP482_RS02020	COG1074	ATP-dependent DNA helicase activity
GP482_RS02050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GP482_RS02065	COG0300	oxidoreductase activity
GP482_RS02070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GP482_RS02070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GP482_RS02075	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GP482_RS02095	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GP482_RS02100	COG2384	SAM-dependent methyltransferase
GP482_RS02110	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GP482_RS02120	COG1088	dTDP-glucose 4,6-dehydratase activity
GP482_RS02125	COG1051	belongs to the nudix hydrolase family
GP482_RS02130	COG0628	permease
GP482_RS02135	COG0457	Tetratricopeptide repeat
GP482_RS02145	COG0028	Belongs to the TPP enzyme family
GP482_RS02150	COG3527	Alpha-acetolactate decarboxylase
GP482_RS02155	COG0531	amino acid
GP482_RS02165	COG0583	DNA-binding transcription factor activity
GP482_RS02170	COG1126	abc transporter atp-binding protein
GP482_RS02175	COG0765	amino acid transport
GP482_RS02185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GP482_RS02190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GP482_RS02195	COG4187	Peptidase family M20/M25/M40
GP482_RS02205	COG4120	Belongs to the binding-protein-dependent transport system permease family
GP482_RS02210	COG3842	ATPase activity
GP482_RS02225	COG0488	(ABC) transporter
GP482_RS02235	COG1132	(ABC) transporter
GP482_RS02240	COG1132	(ABC) transporter
GP482_RS02250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GP482_RS02260	COG0789	Transcriptional regulator
GP482_RS02290	COG1136	(ABC) transporter
GP482_RS02295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GP482_RS02300	COG1011	Hydrolase
GP482_RS02310	COG0583	DNA-binding transcription factor activity
GP482_RS02315	COG2855	membrane
GP482_RS02325	COG0322	excinuclease ABC activity
GP482_RS02345	COG1573	uracil-dna glycosylase
GP482_RS02370	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GP482_RS02395	COG1316	TRANSCRIPTIONal
GP482_RS02430	COG1442	glycosyl transferase family 8
GP482_RS02430	COG1216	Glycosyl transferase, family 2
GP482_RS02455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GP482_RS02500	COG1091	dTDP-4-dehydrorhamnose reductase activity
GP482_RS02525	COG0167	dihydroorotate dehydrogenase activity
GP482_RS02530	COG0284	orotidine-5'-phosphate decarboxylase activity
GP482_RS02535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GP482_RS02545	COG1881	PFAM PEBP family protein
GP482_RS02565	COG0187	DNA topoisomerase II activity
GP482_RS02575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GP482_RS02580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GP482_RS02600	COG0539	negative regulation of cytoplasmic translation
GP482_RS02610	COG1346	cytolysis
GP482_RS02615	COG1380	Effector of murein hydrolase LrgA
GP482_RS02635	COG1131	(ABC) transporter
GP482_RS02640	COG1725	Transcriptional regulator
GP482_RS02650	COG0205	6-phosphofructokinase activity
GP482_RS02655	COG0469	pyruvate kinase activity
GP482_RS02670	COG2824	Alkylphosphonate utilization operon protein PhnA
GP482_RS02675	COG0765	amino acid transport
GP482_RS02680	COG1126	abc transporter atp-binding protein
GP482_RS02695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GP482_RS02700	COG1115	amino acid carrier protein
GP482_RS02705	COG2723	6-phospho-beta-galactosidase activity
GP482_RS02710	COG0406	alpha-ribazole phosphatase activity
GP482_RS02715	COG0628	permease
GP482_RS02725	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GP482_RS02735	COG1104	cysteine desulfurase activity
GP482_RS02740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GP482_RS02745	COG4116	CYTH
GP482_RS02750	COG2357	RelA SpoT domain protein
GP482_RS02760	COG0564	pseudouridine synthase activity
GP482_RS02765	COG0280	phosphate acetyltransferase
GP482_RS02770	COG4221	oxidoreductase activity
GP482_RS02780	COG0561	phosphatase activity
GP482_RS02785	COG2723	6-phospho-beta-galactosidase activity
GP482_RS02790	COG1136	(ABC) transporter
GP482_RS02795	COG0577	efflux transmembrane transporter activity
GP482_RS02800	COG0516	GMP reductase activity
GP482_RS02810	COG2233	PERMEase
GP482_RS02835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GP482_RS02840	COG2890	protein-(glutamine-N5) methyltransferase activity
GP482_RS02845	COG0009	L-threonylcarbamoyladenylate synthase
GP482_RS02850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GP482_RS02870	COG1132	(ABC) transporter
GP482_RS02885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GP482_RS02890	COG0022	dehydrogenase e1 component
GP482_RS02890	COG0508	dehydrogenase complex catalyzes the overall conversion of
GP482_RS02895	COG0508	dehydrogenase complex catalyzes the overall conversion of
GP482_RS02900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GP482_RS02915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GP482_RS02920	COG0095	Lipoate-protein ligase
GP482_RS02955	COG1937	Protein conserved in bacteria
GP482_RS02965	COG0446	pyridine nucleotide-disulphide oxidoreductase
GP482_RS02970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GP482_RS02975	COG1418	mRNA catabolic process
GP482_RS02985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GP482_RS02985	COG0519	Catalyzes the synthesis of GMP from XMP
GP482_RS03025	COG1396	sequence-specific DNA binding
GP482_RS03030	COG0366	Alpha amylase catalytic
GP482_RS03030	COG5263	repeat protein
GP482_RS03045	COG0534	Mate efflux family protein
GP482_RS03050	COG1461	Dihydroxyacetone kinase
GP482_RS03055	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GP482_RS03095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GP482_RS03125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GP482_RS03210	COG1132	(ABC) transporter
GP482_RS03230	COG1129	ABC transporter
GP482_RS03235	COG4974	Belongs to the 'phage' integrase family
GP482_RS03245	COG5002	protein histidine kinase activity
GP482_RS03250	COG0745	RESPONSE REGULATOR receiver
GP482_RS03255	COG0577	efflux transmembrane transporter activity
GP482_RS03260	COG1136	(ABC) transporter
GP482_RS03290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GP482_RS03295	COG0758	DNA mediated transformation
GP482_RS03300	COG0110	maltose O-acetyltransferase activity
GP482_RS03305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GP482_RS03310	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GP482_RS03400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GP482_RS03435	COG0488	(ABC) transporter
GP482_RS03450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GP482_RS03460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GP482_RS03465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GP482_RS03480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GP482_RS03485	COG4684	Psort location CytoplasmicMembrane, score
GP482_RS03490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GP482_RS03510	COG0346	lactoylglutathione lyase activity
GP482_RS03515	COG3764	Sortase (surface protein transpeptidase)
GP482_RS03550	COG1744	ABC transporter substrate-binding protein PnrA-like
GP482_RS03560	COG2813	Specifically methylates the guanine in position
GP482_RS03575	COG5002	protein histidine kinase activity
GP482_RS03580	COG0745	RESPONSE REGULATOR receiver
GP482_RS03590	COG0704	Plays a role in the regulation of phosphate uptake
GP482_RS03600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GP482_RS03605	COG0581	inorganic phosphate transmembrane transporter activity
GP482_RS03610	COG0573	inorganic phosphate transmembrane transporter activity
GP482_RS03615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GP482_RS03620	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GP482_RS03620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GP482_RS03625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GP482_RS03645	COG0483	inositol monophosphate 1-phosphatase activity
GP482_RS03650	COG4476	Belongs to the UPF0223 family
GP482_RS03655	COG1393	Belongs to the ArsC family
GP482_RS03660	COG0196	riboflavin kinase activity
GP482_RS03665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GP482_RS03695	COG1136	(ABC) transporter
GP482_RS03695	COG0577	efflux transmembrane transporter activity
GP482_RS03725	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GP482_RS03735	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GP482_RS03785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GP482_RS03790	COG1115	amino acid carrier protein
GP482_RS03795	COG0561	phosphatase activity
GP482_RS03815	COG0561	phosphatase activity
GP482_RS03820	COG0656	L-ascorbic acid biosynthetic process
GP482_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
GP482_RS03830	COG0110	maltose O-acetyltransferase activity
GP482_RS03840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GP482_RS03850	COG1447	Phosphotransferase system cellobiose-specific component IIA
GP482_RS03855	COG3711	transcriptional antiterminator
GP482_RS03855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GP482_RS03860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GP482_RS03885	COG2723	6-phospho-beta-galactosidase activity
GP482_RS03900	COG2207	Transcriptional regulator
GP482_RS03905	COG2190	(PTS) system
GP482_RS03905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GP482_RS03905	COG1263	PTS System
GP482_RS03910	COG3711	transcriptional antiterminator
GP482_RS03920	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GP482_RS03925	COG1177	transmembrane transport
GP482_RS03930	COG1176	ABC-type spermidine putrescine transport system, permease component I
GP482_RS03965	COG0285	dihydrofolate synthase activity
GP482_RS03970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GP482_RS03975	COG2962	Rard protein
GP482_RS03990	COG0726	polysaccharide deacetylase
GP482_RS04005	COG0222	ribosome binding
GP482_RS04010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GP482_RS04025	COG2040	homocysteine
GP482_RS04030	COG0833	amino acid
GP482_RS04050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GP482_RS04060	COG3425	synthase
GP482_RS04075	COG1272	protein, Hemolysin III
GP482_RS04095	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GP482_RS04105	COG1126	abc transporter atp-binding protein
GP482_RS04110	COG0765	amino acid transport
GP482_RS04120	COG1126	abc transporter atp-binding protein
GP482_RS04125	COG0765	amino acid transport
GP482_RS04130	COG0765	amino acid transport
GP482_RS04135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GP482_RS04145	COG0583	DNA-binding transcription factor activity
GP482_RS04150	COG0656	L-ascorbic acid biosynthetic process
GP482_RS04170	COG5002	protein histidine kinase activity
GP482_RS04175	COG0745	RESPONSE REGULATOR receiver
GP482_RS04180	COG2357	RelA SpoT domain protein
GP482_RS04185	COG1132	(ABC) transporter
GP482_RS04190	COG1132	(ABC) transporter
GP482_RS04200	COG0242	peptide deformylase activity
GP482_RS04205	COG1247	-acetyltransferase
GP482_RS04210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GP482_RS04225	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GP482_RS04230	COG0602	queuosine metabolic process
GP482_RS04235	COG0720	synthase
GP482_RS04240	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GP482_RS04245	COG1132	(ABC) transporter
GP482_RS04255	COG0488	(ABC) transporter
GP482_RS04280	COG1388	LysM domain
GP482_RS04280	COG1705	Flagellar rod assembly protein muramidase FlgJ
GP482_RS04285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GP482_RS04290	COG0646	methionine synthase
GP482_RS04290	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GP482_RS04295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GP482_RS04300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GP482_RS04300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GP482_RS04300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GP482_RS04305	COG1105	Belongs to the carbohydrate kinase PfkB family
GP482_RS04310	COG1349	DNA-binding transcription factor activity
GP482_RS04315	COG0492	ferredoxin-NADP+ reductase activity
GP482_RS04320	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GP482_RS04330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GP482_RS04345	COG1837	Belongs to the UPF0109 family
GP482_RS04365	COG0577	efflux transmembrane transporter activity
GP482_RS04370	COG1136	(ABC) transporter
GP482_RS04385	COG0505	Belongs to the CarA family
GP482_RS04390	COG0540	Belongs to the ATCase OTCase family
GP482_RS04405	COG0564	pseudouridine synthase activity
GP482_RS04415	COG0583	DNA-binding transcription factor activity
GP482_RS04420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GP482_RS04445	COG0301	tRNA thio-modification
GP482_RS04450	COG1104	cysteine desulfurase activity
GP482_RS04460	COG0285	dihydrofolate synthase activity
GP482_RS04475	COG0287	Prephenate dehydrogenase
GP482_RS04485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GP482_RS04490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GP482_RS04500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GP482_RS04505	COG1368	sulfuric ester hydrolase activity
GP482_RS04515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GP482_RS04520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GP482_RS04525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GP482_RS04545	COG2195	Cleaves the N-terminal amino acid of tripeptides
GP482_RS04560	COG3942	CHAP domain
GP482_RS04565	COG0463	Glycosyl transferase, family 2
GP482_RS04580	COG1368	sulfuric ester hydrolase activity
GP482_RS04605	COG1442	glycosyl transferase family 8
GP482_RS04605	COG1216	Glycosyl transferase, family 2
GP482_RS04620	COG0444	Belongs to the ABC transporter superfamily
GP482_RS04625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GP482_RS04630	COG0601	transmembrane transport
GP482_RS04635	COG4166	transmembrane transport
GP482_RS04640	COG2151	metal-sulfur cluster biosynthetic enzyme
GP482_RS04645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GP482_RS04650	COG0358	DNA primase activity
GP482_RS04655	COG1970	mechanosensitive ion channel activity
GP482_RS04675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GP482_RS04685	COG0058	SHG alpha-glucan phosphorylase activity
GP482_RS04690	COG1640	4-alpha-glucanotransferase
GP482_RS04695	COG1609	Transcriptional regulator
GP482_RS04705	COG1175	transmembrane transport
GP482_RS04710	COG3833	ABC-type maltose transport systems, permease component
GP482_RS04715	COG2816	NAD+ diphosphatase activity
GP482_RS04720	COG0556	nucleotide-excision repair
GP482_RS04730	COG1126	abc transporter atp-binding protein
GP482_RS04735	COG1592	Rubrerythrin
GP482_RS04740	COG0488	(ABC) transporter
GP482_RS04760	COG1187	pseudouridine synthase activity
GP482_RS04765	COG4166	transmembrane transport
GP482_RS04770	COG4166	transmembrane transport
GP482_RS04775	COG0659	secondary active sulfate transmembrane transporter activity
GP482_RS04810	COG0454	-acetyltransferase
GP482_RS04815	COG0456	acetyltransferase
GP482_RS04860	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GP482_RS04875	COG0602	queuosine metabolic process
GP482_RS04880	COG1396	sequence-specific DNA binding
GP482_RS04890	COG2211	Major facilitator Superfamily
GP482_RS04905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GP482_RS04910	COG1316	TRANSCRIPTIONal
GP482_RS04915	COG0077	Prephenate dehydratase
GP482_RS04920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GP482_RS04925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GP482_RS04960	COG1518	maintenance of DNA repeat elements
GP482_RS04965	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GP482_RS04980	COG0647	UMP catabolic process
GP482_RS04990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GP482_RS05005	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GP482_RS05010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GP482_RS05015	COG3442	glutamine amidotransferase
GP482_RS05020	COG0148	phosphopyruvate hydratase activity
GP482_RS05035	COG1523	belongs to the glycosyl hydrolase 13 family
GP482_RS05050	COG0107	imidazoleglycerol-phosphate synthase activity
GP482_RS05060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GP482_RS05070	COG0560	Phosphoserine phosphatase
GP482_RS05075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GP482_RS05085	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GP482_RS05100	COG0187	DNA topoisomerase II activity
GP482_RS05110	COG0772	Belongs to the SEDS family
GP482_RS05125	COG0038	chloride channel
GP482_RS05135	COG0398	Pfam SNARE associated Golgi protein
GP482_RS05145	COG0716	FMN binding
GP482_RS05155	COG1454	alcohol dehydrogenase
GP482_RS05160	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GP482_RS05165	COG0254	rRNA binding
GP482_RS05170	COG1705	Flagellar rod assembly protein muramidase FlgJ
GP482_RS05170	COG1388	LysM domain
GP482_RS05205	COG1309	transcriptional regulator
GP482_RS05220	COG0251	oxidation-reduction process
GP482_RS05240	COG0017	Asparaginyl-tRNA synthetase
GP482_RS05250	COG0436	Aminotransferase
GP482_RS05260	COG1199	ATP-dependent helicase activity
GP482_RS05260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GP482_RS05275	COG2177	Part of the ABC transporter FtsEX involved in
GP482_RS05280	COG2884	Cell division ATP-binding protein ftsE
GP482_RS05290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GP482_RS05310	COG1078	dGTPase activity
GP482_RS05330	COG0149	triose-phosphate isomerase activity
GP482_RS05335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GP482_RS05340	COG0772	Belongs to the SEDS family
GP482_RS05350	COG1164	Oligoendopeptidase f
GP482_RS05355	COG0386	Belongs to the glutathione peroxidase family
GP482_RS05375	COG0588	phosphoglycerate mutase activity
GP482_RS05400	COG1309	transcriptional regulator
GP482_RS05410	COG4443	Transcriptional Coactivator p15 (PC4)
GP482_RS05460	COG3091	SprT-like family
GP482_RS05465	COG2183	response to ionizing radiation
GP482_RS05475	COG0701	Predicted permease
GP482_RS05480	COG3689	TIGRFAM TIGR03943 family protein
GP482_RS05490	COG0552	protein localization to endoplasmic reticulum
GP482_RS05495	COG0561	phosphatase activity
GP482_RS05500	COG0561	phosphatase activity
GP482_RS05510	COG1196	nuclear chromosome segregation
GP482_RS05520	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GP482_RS05525	COG5002	protein histidine kinase activity
GP482_RS05530	COG0745	RESPONSE REGULATOR receiver
GP482_RS05535	COG1126	abc transporter atp-binding protein
GP482_RS05540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GP482_RS05545	COG0765	amino acid transport
GP482_RS05550	COG0765	amino acid transport
GP482_RS05565	COG3850	Histidine kinase
GP482_RS05565	COG5002	protein histidine kinase activity
GP482_RS05570	COG0745	RESPONSE REGULATOR receiver
GP482_RS05590	COG4716	Myosin-crossreactive antigen
GP482_RS05600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GP482_RS05605	COG0438	transferase activity, transferring glycosyl groups
GP482_RS05615	COG1609	Transcriptional regulator
GP482_RS05620	COG0006	proline dipeptidase activity
GP482_RS05625	COG2816	NAD+ diphosphatase activity
GP482_RS05630	COG0583	DNA-binding transcription factor activity
GP482_RS05635	COG1811	Na channel or pump
GP482_RS05650	COG0778	Nitroreductase
GP482_RS05665	COG1846	Transcriptional regulator
GP482_RS05675	COG0557	exoribonuclease II activity
GP482_RS05690	COG2814	Major facilitator Superfamily
GP482_RS05695	COG0237	dephospho-CoA kinase activity
GP482_RS05700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GP482_RS05710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GP482_RS05720	COG0366	Alpha amylase catalytic
GP482_RS05725	COG0519	Catalyzes the synthesis of GMP from XMP
GP482_RS05740	COG1702	phosphate starvation-inducible protein PhoH
GP482_RS05745	COG4479	Belongs to the UPF0346 family
GP482_RS05755	COG2996	Protein conserved in bacteria
GP482_RS05785	COG1674	ftsk spoiiie
GP482_RS05815	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GP482_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
GP482_RS05860	COG0640	Transcriptional regulator
GP482_RS05865	COG0708	Exodeoxyribonuclease III
GP482_RS05875	COG1136	(ABC) transporter
GP482_RS05890	COG2197	response regulator
GP482_RS05900	COG1393	Belongs to the ArsC family
GP482_RS05905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GP482_RS05925	COG0004	ammonium transporteR
GP482_RS05940	COG1774	PSP1 C-terminal conserved region
GP482_RS05945	COG0470	DNA polymerase III
GP482_RS05955	COG0517	IMP dehydrogenase activity
GP482_RS05955	COG1227	inorganic diphosphatase activity
GP482_RS05960	COG0410	ABC transporter
GP482_RS05975	COG0559	Belongs to the binding-protein-dependent transport system permease family
GP482_RS05985	COG4471	UPF0298 protein
GP482_RS06005	COG0583	DNA-binding transcription factor activity
GP482_RS06015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GP482_RS06020	COG0626	cystathionine gamma-synthase activity
GP482_RS06025	COG2244	polysaccharide biosynthetic process
GP482_RS06035	COG1120	ATPase activity
GP482_RS06040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GP482_RS06045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GP482_RS06050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GP482_RS06065	COG3022	response to hydroperoxide
GP482_RS06070	COG1227	inorganic diphosphatase activity
GP482_RS06080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GP482_RS06085	COG1253	flavin adenine dinucleotide binding
GP482_RS06090	COG2211	Major facilitator Superfamily
GP482_RS06090	COG2190	(PTS) system
GP482_RS06095	COG1119	ATPase activity
GP482_RS06100	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GP482_RS06105	COG1242	4 iron, 4 sulfur cluster binding
GP482_RS06110	COG0671	phosphoesterase, PA-phosphatase related
GP482_RS06115	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GP482_RS06125	COG0531	amino acid
GP482_RS06130	COG0569	domain protein
GP482_RS06135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GP482_RS06140	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GP482_RS06145	COG1187	pseudouridine synthase activity
GP482_RS06160	COG0582	viral genome integration into host DNA
GP482_RS06180	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GP482_RS06185	COG3763	UPF0154 protein
GP482_RS06205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GP482_RS06210	COG1254	Belongs to the acylphosphatase family
GP482_RS06225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GP482_RS06255	COG1484	DNA-dependent DNA replication
GP482_RS06270	COG5002	protein histidine kinase activity
GP482_RS06275	COG0745	RESPONSE REGULATOR receiver
GP482_RS06285	COG0501	Belongs to the peptidase M48B family
GP482_RS06290	COG1704	LemA family
GP482_RS06300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GP482_RS06315	COG1122	ATPase activity
GP482_RS06325	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GP482_RS06330	COG1114	Component of the transport system for branched-chain amino acids
GP482_RS06335	COG2910	NAD(P)H-binding
GP482_RS06340	COG1959	2 iron, 2 sulfur cluster binding
GP482_RS06360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GP482_RS06370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GP482_RS06375	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GP482_RS06380	COG0217	transcriptional regulatory protein
GP482_RS06385	COG0789	Transcriptional regulator
GP482_RS06395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GP482_RS06405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GP482_RS06410	COG1061	Type III restriction enzyme res subunit
GP482_RS06415	COG1002	Type II restriction enzyme, methylase subunits
GP482_RS06420	COG2226	methyltransferase
GP482_RS06425	COG0799	negative regulation of ribosome biogenesis
GP482_RS06430	COG1713	HD superfamily hydrolase involved in NAD metabolism
GP482_RS06435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GP482_RS06440	COG1534	Rna-binding protein
GP482_RS06445	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GP482_RS06450	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GP482_RS06455	COG0477	Major facilitator Superfamily
GP482_RS06460	COG1846	Transcriptional regulator
GP482_RS06480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GP482_RS06490	COG0436	Aminotransferase
GP482_RS06500	COG0589	response to stress
GP482_RS06505	COG0561	phosphatase activity
GP482_RS06510	COG0252	asparaginase activity
GP482_RS06515	COG3655	Transcriptional regulator
GP482_RS06535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GP482_RS06550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GP482_RS06555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GP482_RS06565	COG1940	carbohydrate kinase activity
GP482_RS06570	COG2190	(PTS) system
GP482_RS06570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GP482_RS06570	COG1263	PTS System
GP482_RS06575	COG1621	beta-fructofuranosidase activity
GP482_RS06580	COG1609	Transcriptional regulator
GP482_RS06595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GP482_RS06605	COG2131	deaminase
GP482_RS06610	COG0006	proline dipeptidase activity
GP482_RS06640	COG3655	Transcriptional regulator
GP482_RS06650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GP482_RS06685	COG0681	Belongs to the peptidase S26 family
GP482_RS06695	COG1194	a g-specific adenine glycosylase
GP482_RS06730	COG3118	belongs to the thioredoxin family
GP482_RS06740	COG0157	Belongs to the NadC ModD family
GP482_RS06750	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GP482_RS06755	COG1193	negative regulation of DNA recombination
GP482_RS06770	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GP482_RS06775	COG0681	Belongs to the peptidase S26 family
GP482_RS06780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GP482_RS06795	COG1882	Formate acetyltransferase
GP482_RS06810	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GP482_RS06830	COG5002	protein histidine kinase activity
GP482_RS06840	COG0704	Plays a role in the regulation of phosphate uptake
GP482_RS06845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GP482_RS06850	COG0581	inorganic phosphate transmembrane transporter activity
GP482_RS06855	COG0573	inorganic phosphate transmembrane transporter activity
GP482_RS06860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GP482_RS06870	COG0789	Transcriptional regulator
GP482_RS06885	COG2081	HI0933 family
GP482_RS06900	COG0456	acetyltransferase
GP482_RS06905	COG1214	PFAM Peptidase M22, glycoprotease
GP482_RS06920	COG3942	CHAP domain
GP482_RS06925	COG0493	'glutamate synthase
GP482_RS06930	COG0067	glutamate synthase
GP482_RS06930	COG0069	glutamate synthase activity
GP482_RS06930	COG0070	glutamate synthase
GP482_RS06935	COG0174	glutamine synthetase
GP482_RS06940	COG0789	Transcriptional regulator
GP482_RS06950	COG0126	phosphoglycerate kinase activity
GP482_RS06955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GP482_RS06960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GP482_RS06965	COG0049	tRNA binding
GP482_RS06975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GP482_RS06995	COG1322	Protein conserved in bacteria
GP482_RS07000	COG1564	THIamine pyrophosphokinase
GP482_RS07005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GP482_RS07025	COG3290	protein histidine kinase activity
GP482_RS07030	COG3290	protein histidine kinase activity
GP482_RS07060	COG3279	Response regulator of the LytR AlgR family
GP482_RS07080	COG2274	protein secretion by the type I secretion system
GP482_RS07085	COG1266	CAAX protease self-immunity
GP482_RS07115	COG0084	hydrolase, TatD family'
GP482_RS07120	COG1132	(ABC) transporter
GP482_RS07135	COG0281	malic enzyme
GP482_RS07140	COG0583	DNA-binding transcription factor activity
GP482_RS07145	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GP482_RS07150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GP482_RS07155	COG1696	Membrane protein involved in D-alanine export
GP482_RS07170	COG5002	protein histidine kinase activity
GP482_RS07175	COG0745	RESPONSE REGULATOR receiver
GP482_RS07180	COG2207	Transcriptional regulator
GP482_RS07195	COG0395	ABC-type sugar transport system, permease component
GP482_RS07220	COG2273	Hydrolase Family 16
GP482_RS07250	COG1131	(ABC) transporter
GP482_RS07265	COG0594	ribonuclease P activity
GP482_RS07275	COG0137	argininosuccinate synthase activity
GP482_RS07280	COG2807	transmembrane transport
GP482_RS07285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GP482_RS07295	COG4989	oxidoreductase activity
GP482_RS07310	COG0756	dUTP diphosphatase activity
GP482_RS07325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GP482_RS07335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GP482_RS07340	COG1473	amidohydrolase
GP482_RS07345	COG2171	N-acyltransferase activity
GP482_RS07385	COG1234	tRNA 3'-trailer cleavage
GP482_RS07390	COG1268	BioY protein
GP482_RS07400	COG0343	queuine tRNA-ribosyltransferase activity
GP482_RS07415	COG1832	CoA-binding protein
GP482_RS07420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GP482_RS07420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GP482_RS07440	COG0697	spore germination
GP482_RS07455	COG1181	Belongs to the D-alanine--D-alanine ligase family
GP482_RS07455	COG2918	glutathione biosynthetic process
GP482_RS07470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GP482_RS07475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GP482_RS07480	COG0542	response to heat
GP482_RS07485	COG4463	regulation of RNA biosynthetic process
GP482_RS07495	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GP482_RS07500	COG0052	Belongs to the universal ribosomal protein uS2 family
GP482_RS07510	COG1619	proteins homologs of microcin C7 resistance protein MccF
GP482_RS07540	COG1396	sequence-specific DNA binding
GP482_RS07545	COG3590	peptidase
GP482_RS07575	COG1309	transcriptional regulator
GP482_RS07580	COG0602	queuosine metabolic process
GP482_RS07590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GP482_RS07590	COG1328	CTP reductase activity
GP482_RS07600	COG3906	Belongs to the UPF0473 family
GP482_RS07610	COG4472	Bacterial protein of unknown function (DUF965)
GP482_RS07615	COG1393	Belongs to the ArsC family
GP482_RS07625	COG1058	Belongs to the CinA family
GP482_RS07625	COG1546	Belongs to the CinA family
GP482_RS07635	COG0519	Catalyzes the synthesis of GMP from XMP
GP482_RS07680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GP482_RS07685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GP482_RS07745	COG0681	Belongs to the peptidase S26 family
GP482_RS07835	COG1674	ftsk spoiiie
GP482_RS07840	COG4499	WXG100 protein secretion system (Wss), protein YukC
GP482_RS07855	COG4842	Belongs to the WXG100 family
GP482_RS07875	COG3759	membrane
GP482_RS07880	COG1511	domain protein
GP482_RS07880	COG1511	domain protein
GP482_RS07895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GP482_RS07900	COG4466	Protein conserved in bacteria
GP482_RS07905	COG0305	Participates in initiation and elongation during chromosome replication
GP482_RS07920	COG0445	tRNA wobble uridine modification
GP482_RS07930	COG1760	l-serine dehydratase
GP482_RS07935	COG1760	l-serine dehydratase
GP482_RS07945	COG0741	lytic transglycosylase activity
GP482_RS07960	COG1122	ATPase activity
GP482_RS07970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GP482_RS07980	COG0612	Peptidase, M16
GP482_RS07985	COG0612	Peptidase, M16
GP482_RS07995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GP482_RS08000	COG4975	Glucose uptake
GP482_RS08020	COG0488	(ABC) transporter
GP482_RS08050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GP482_RS08055	COG1475	DNA binding
GP482_RS08065	COG0592	DNA-directed DNA polymerase activity
GP482_RS08070	COG1597	lipid kinase activity
GP482_RS08080	COG0012	GTP binding
GP482_RS08085	COG0193	aminoacyl-tRNA hydrolase activity
GP482_RS08090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GP482_RS08100	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GP482_RS08130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GP482_RS08305	COG1792	Involved in formation and maintenance of cell shape
GP482_RS08315	COG3942	CHAP domain
GP482_RS08325	COG0436	Aminotransferase
GP482_RS08330	COG1381	Involved in DNA repair and RecF pathway recombination
GP482_RS08335	COG0416	fatty acid biosynthetic process
GP482_RS08340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GP482_RS08345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GP482_RS08350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GP482_RS08360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GP482_RS08365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GP482_RS08380	COG1683	Conserved Protein
GP482_RS08385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GP482_RS08400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GP482_RS08415	COG2255	four-way junction helicase activity
GP482_RS08425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GP482_RS08435	COG2755	lipolytic protein G-D-S-L family
GP482_RS08435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GP482_RS08450	COG0534	Mate efflux family protein
GP482_RS08455	COG0051	transcription antitermination factor activity, RNA binding
GP482_RS08465	COG0088	Forms part of the polypeptide exit tunnel
GP482_RS08470	COG0089	rRNA binding
GP482_RS08495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GP482_RS08500	COG0255	Belongs to the universal ribosomal protein uL29 family
GP482_RS08515	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GP482_RS08525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GP482_RS08545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GP482_RS08550	COG1841	ribosomal large subunit assembly
GP482_RS08560	COG0201	protein transport
GP482_RS08575	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GP482_RS08585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GP482_RS08590	COG0202	RNA polymerase activity
GP482_RS08595	COG0203	ribosomal protein L17
GP482_RS08715	COG1674	ftsk spoiiie
GP482_RS08755	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GP482_RS08765	COG1121	(ABC) transporter
GP482_RS08770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GP482_RS08790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GP482_RS08800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GP482_RS08805	COG1459	type II secretion system
GP482_RS08810	COG4537	Required for transformation and DNA binding
GP482_RS08865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GP482_RS08870	COG1363	Peptidase, m42
GP482_RS08880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GP482_RS08885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GP482_RS08900	COG0561	phosphatase activity
GP482_RS08905	COG1621	beta-fructofuranosidase activity
GP482_RS08905	COG3583	domain protein
GP482_RS08905	COG5492	domain, Protein
GP482_RS08915	COG4585	Histidine kinase
GP482_RS08920	COG2197	response regulator
GP482_RS08940	COG3715	PTS system
GP482_RS08945	COG3716	PTS system mannose fructose sorbose family IID component
GP482_RS08955	COG1396	sequence-specific DNA binding
GP482_RS08970	COG4120	Belongs to the binding-protein-dependent transport system permease family
GP482_RS08975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GP482_RS08990	COG1396	sequence-specific DNA binding
GP482_RS09000	COG0564	pseudouridine synthase activity
GP482_RS09010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GP482_RS09030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GP482_RS09035	COG4667	esterase of the alpha-beta hydrolase superfamily
GP482_RS09045	COG2017	converts alpha-aldose to the beta-anomer
GP482_RS09050	COG2249	NAD(P)H dehydrogenase (quinone) activity
GP482_RS09070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GP482_RS09075	COG0456	acetyltransferase
GP482_RS09095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GP482_RS09105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GP482_RS09105	COG1263	PTS System
GP482_RS09105	COG2190	(PTS) system
GP482_RS09115	COG1363	Peptidase, m42
GP482_RS09125	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GP482_RS09130	COG1447	Phosphotransferase system cellobiose-specific component IIA
GP482_RS09135	COG2723	6-phospho-beta-galactosidase activity
GP482_RS09140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GP482_RS09145	COG2188	Transcriptional regulator
GP482_RS09150	COG1482	cell wall glycoprotein biosynthetic process
GP482_RS09160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GP482_RS09165	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GP482_RS09175	COG2188	Transcriptional regulator
GP482_RS09180	COG1940	carbohydrate kinase activity
GP482_RS09200	COG3842	ATPase activity
GP482_RS09210	COG0698	ribose 5-phosphate isomerase
GP482_RS09220	COG1105	Belongs to the carbohydrate kinase PfkB family
GP482_RS09235	COG3711	transcriptional antiterminator
GP482_RS09240	COG2723	6-phospho-beta-galactosidase activity
GP482_RS09245	COG1447	Phosphotransferase system cellobiose-specific component IIA
GP482_RS09250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GP482_RS09250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GP482_RS09255	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GP482_RS09260	COG1131	(ABC) transporter
GP482_RS09270	COG2207	Transcriptional regulator
GP482_RS09275	COG3345	alpha-galactosidase
GP482_RS09280	COG1653	transport
GP482_RS09285	COG1175	transmembrane transport
GP482_RS09290	COG0395	ABC-type sugar transport system, permease component
GP482_RS09295	COG0366	Alpha amylase catalytic
GP482_RS09300	COG0366	Alpha amylase catalytic
GP482_RS09395	COG1609	Transcriptional regulator
GP482_RS09400	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GP482_RS09405	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GP482_RS09410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GP482_RS09420	COG1862	Preprotein translocase
GP482_RS09425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GP482_RS09430	COG4589	Belongs to the CDS family
GP482_RS09495	COG1674	ftsk spoiiie
GP482_RS09505	COG2946	Replication initiation factor
GP482_RS09535	COG0791	NLP P60 protein
GP482_RS09535	COG0741	lytic transglycosylase activity
