locus-tag	class	description
GO995_RS00015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GO995_RS00055	COG0681	Belongs to the peptidase S26 family
GO995_RS00080	COG3759	membrane
GO995_RS00085	COG1511	domain protein
GO995_RS00100	COG4466	Protein conserved in bacteria
GO995_RS00105	COG0305	Participates in initiation and elongation during chromosome replication
GO995_RS00120	COG0445	tRNA wobble uridine modification
GO995_RS00130	COG1760	l-serine dehydratase
GO995_RS00135	COG1760	l-serine dehydratase
GO995_RS00145	COG0741	lytic transglycosylase activity
GO995_RS00155	COG0582	viral genome integration into host DNA
GO995_RS00225	COG1122	ATPase activity
GO995_RS00235	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GO995_RS00245	COG0612	Peptidase, M16
GO995_RS00250	COG0612	Peptidase, M16
GO995_RS00260	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GO995_RS00270	COG0517	IMP dehydrogenase activity
GO995_RS00270	COG0516	GMP reductase activity
GO995_RS00285	COG0488	(ABC) transporter
GO995_RS00315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO995_RS00320	COG1475	DNA binding
GO995_RS00330	COG0592	DNA-directed DNA polymerase activity
GO995_RS00335	COG1597	lipid kinase activity
GO995_RS00355	COG0012	GTP binding
GO995_RS00365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GO995_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GO995_RS00405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GO995_RS00580	COG1792	Involved in formation and maintenance of cell shape
GO995_RS00590	COG3942	CHAP domain
GO995_RS00600	COG0436	Aminotransferase
GO995_RS00610	COG0416	fatty acid biosynthetic process
GO995_RS00615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO995_RS00620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO995_RS00625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GO995_RS00640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GO995_RS00645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GO995_RS00660	COG1683	Conserved Protein
GO995_RS00665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GO995_RS00680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GO995_RS00690	COG2255	four-way junction helicase activity
GO995_RS00700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GO995_RS00710	COG2755	lipolytic protein G-D-S-L family
GO995_RS00710	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GO995_RS00720	COG0534	Mate efflux family protein
GO995_RS00725	COG0051	transcription antitermination factor activity, RNA binding
GO995_RS00735	COG0088	Forms part of the polypeptide exit tunnel
GO995_RS00740	COG0089	rRNA binding
GO995_RS00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GO995_RS00770	COG0255	Belongs to the universal ribosomal protein uL29 family
GO995_RS00785	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GO995_RS00795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GO995_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GO995_RS00820	COG1841	ribosomal large subunit assembly
GO995_RS00830	COG0201	protein transport
GO995_RS00855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GO995_RS00860	COG0202	RNA polymerase activity
GO995_RS00865	COG0203	ribosomal protein L17
GO995_RS00975	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GO995_RS00985	COG1121	(ABC) transporter
GO995_RS00990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO995_RS01020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GO995_RS01025	COG1459	type II secretion system
GO995_RS01030	COG4537	Required for transformation and DNA binding
GO995_RS01085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GO995_RS01090	COG1363	Peptidase, m42
GO995_RS01100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GO995_RS01105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO995_RS01120	COG0561	phosphatase activity
GO995_RS01125	COG3583	domain protein
GO995_RS01125	COG1621	beta-fructofuranosidase activity
GO995_RS01125	COG5492	domain, Protein
GO995_RS01135	COG4585	Histidine kinase
GO995_RS01140	COG2197	response regulator
GO995_RS01160	COG3715	PTS system
GO995_RS01165	COG3716	PTS system mannose fructose sorbose family IID component
GO995_RS01175	COG1396	sequence-specific DNA binding
GO995_RS01190	COG4120	Belongs to the binding-protein-dependent transport system permease family
GO995_RS01195	COG1116	anion transmembrane transporter activity
GO995_RS01195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO995_RS01210	COG1396	sequence-specific DNA binding
GO995_RS01220	COG0564	pseudouridine synthase activity
GO995_RS01230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO995_RS01250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO995_RS01255	COG4667	esterase of the alpha-beta hydrolase superfamily
GO995_RS01265	COG2017	converts alpha-aldose to the beta-anomer
GO995_RS01290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GO995_RS01295	COG0456	acetyltransferase
GO995_RS01310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GO995_RS01320	COG1263	PTS System
GO995_RS01320	COG2190	(PTS) system
GO995_RS01320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO995_RS01330	COG1363	Peptidase, m42
GO995_RS01340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO995_RS01345	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO995_RS01350	COG2723	6-phospho-beta-galactosidase activity
GO995_RS01355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO995_RS01360	COG2188	Transcriptional regulator
GO995_RS01365	COG1482	cell wall glycoprotein biosynthetic process
GO995_RS01375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GO995_RS01380	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GO995_RS01390	COG2188	Transcriptional regulator
GO995_RS01395	COG1940	carbohydrate kinase activity
GO995_RS01415	COG3842	ATPase activity
GO995_RS01425	COG0698	ribose 5-phosphate isomerase
GO995_RS01450	COG3711	transcriptional antiterminator
GO995_RS01455	COG2723	6-phospho-beta-galactosidase activity
GO995_RS01460	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO995_RS01465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO995_RS01465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO995_RS01470	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GO995_RS01475	COG1131	(ABC) transporter
GO995_RS01485	COG2207	Transcriptional regulator
GO995_RS01490	COG3345	alpha-galactosidase
GO995_RS01495	COG1653	transport
GO995_RS01500	COG1175	transmembrane transport
GO995_RS01505	COG0395	ABC-type sugar transport system, permease component
GO995_RS01510	COG0366	Alpha amylase catalytic
GO995_RS01515	COG0366	Alpha amylase catalytic
GO995_RS01520	COG1609	Transcriptional regulator
GO995_RS01525	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GO995_RS01530	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GO995_RS01535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GO995_RS01545	COG1862	Preprotein translocase
GO995_RS01550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GO995_RS01555	COG4589	Belongs to the CDS family
GO995_RS01610	COG1012	belongs to the aldehyde dehydrogenase family
GO995_RS01610	COG1454	alcohol dehydrogenase
GO995_RS01620	COG1185	polyribonucleotide nucleotidyltransferase activity
GO995_RS01630	COG1045	serine acetyltransferase
GO995_RS01640	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GO995_RS01675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GO995_RS01715	COG3830	Belongs to the UPF0237 family
GO995_RS01730	COG1876	peptidase activity
GO995_RS01735	COG1705	Flagellar rod assembly protein muramidase FlgJ
GO995_RS01750	COG0443	Heat shock 70 kDa protein
GO995_RS01805	COG0668	transmembrane transport
GO995_RS01820	COG0504	CTP synthase activity
GO995_RS01835	COG0191	fructose-bisphosphate aldolase activity
GO995_RS01840	COG0582	viral genome integration into host DNA
GO995_RS01855	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GO995_RS01865	COG1461	Dihydroxyacetone kinase
GO995_RS01870	COG0129	dihydroxy-acid dehydratase activity
GO995_RS01875	COG0028	Belongs to the TPP enzyme family
GO995_RS01880	COG0440	acetolactate synthase activity
GO995_RS01890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GO995_RS01905	COG1126	abc transporter atp-binding protein
GO995_RS01910	COG0765	amino acid transport
GO995_RS01930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GO995_RS01940	COG0719	Fe-S assembly protein
GO995_RS01945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GO995_RS01955	COG0719	Fe-S assembly protein
GO995_RS01960	COG1686	Belongs to the peptidase S11 family
GO995_RS01965	COG4166	transmembrane transport
GO995_RS01970	COG0601	transmembrane transport
GO995_RS01975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO995_RS01980	COG0444	Belongs to the ABC transporter superfamily
GO995_RS01985	COG4608	Belongs to the ABC transporter superfamily
GO995_RS02020	COG0527	aspartate kinase activity
GO995_RS02025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO995_RS02030	COG1024	Enoyl-CoA hydratase
GO995_RS02040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GO995_RS02055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GO995_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
GO995_RS02065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO995_RS02080	COG0439	Biotin carboxylase
GO995_RS02095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GO995_RS02105	COG3716	PTS system mannose fructose sorbose family IID component
GO995_RS02110	COG3715	PTS system
GO995_RS02120	COG0561	phosphatase activity
GO995_RS02135	COG2252	PERMEase
GO995_RS02140	COG0802	atpase or kinase
GO995_RS02150	COG1316	TRANSCRIPTIONal
GO995_RS02160	COG0537	adenosine 5'-monophosphoramidase activity
GO995_RS02165	COG1131	(ABC) transporter
GO995_RS02170	COG4473	ABC transporter
GO995_RS02180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GO995_RS02185	COG3447	MASE1 domain protein
GO995_RS02185	COG5002	protein histidine kinase activity
GO995_RS02185	COG5001	Diguanylate cyclase
GO995_RS02210	COG0195	Participates in both transcription termination and antitermination
GO995_RS02215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GO995_RS02225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GO995_RS02230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GO995_RS02235	COG1611	Belongs to the LOG family
GO995_RS02250	COG2217	Heavy metal translocating P-type atpase
GO995_RS02260	COG2860	membrane
GO995_RS02265	COG0561	phosphatase activity
GO995_RS02290	COG1283	sodium-dependent phosphate transmembrane transporter activity
GO995_RS02325	COG1131	(ABC) transporter
GO995_RS02335	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GO995_RS02345	COG0275	rRNA processing
GO995_RS02355	COG0768	penicillin binding
GO995_RS02360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GO995_RS02365	COG0513	Belongs to the DEAD box helicase family
GO995_RS02380	COG1126	abc transporter atp-binding protein
GO995_RS02390	COG0492	ferredoxin-NADP+ reductase activity
GO995_RS02395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GO995_RS02405	COG3579	cysteine-type endopeptidase activity
GO995_RS02410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO995_RS02415	COG3331	DNA recombination
GO995_RS02425	COG3599	regulation of cell shape
GO995_RS02435	COG0116	Belongs to the methyltransferase superfamily
GO995_RS02450	COG1854	S-ribosylhomocysteine lyase activity
GO995_RS02470	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GO995_RS02480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GO995_RS02480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GO995_RS02490	COG0515	serine threonine protein kinase
GO995_RS02490	COG2815	serine threonine protein kinase
GO995_RS02500	COG4585	Histidine kinase
GO995_RS02505	COG2197	response regulator
GO995_RS02515	COG1098	S1 RNA binding domain
GO995_RS02525	COG1739	Uncharacterized protein family UPF0029
GO995_RS02530	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GO995_RS02535	COG1040	competence protein
GO995_RS02605	COG3557	Belongs to the UPF0374 family
GO995_RS02610	COG2137	regulation of response to DNA damage stimulus
GO995_RS02620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO995_RS02635	COG1428	Deoxynucleoside kinase
GO995_RS02655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO995_RS02665	COG1396	sequence-specific DNA binding
GO995_RS02680	COG4716	Myosin-crossreactive antigen
GO995_RS02705	COG0742	ribosomal rna small subunit methyltransferase
GO995_RS02715	COG3480	Lon protease (S16) C-terminal proteolytic domain
GO995_RS02725	COG0737	Belongs to the 5'-nucleotidase family
GO995_RS02730	COG4470	Protein conserved in bacteria
GO995_RS02745	COG1132	(ABC) transporter
GO995_RS02750	COG1132	(ABC) transporter
GO995_RS02755	COG1131	(ABC) transporter
GO995_RS02765	COG4585	Histidine kinase
GO995_RS02770	COG2197	response regulator
GO995_RS02780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO995_RS02785	COG0512	Glutamine amidotransferase of anthranilate synthase
GO995_RS02800	COG0135	phosphoribosylanthranilate isomerase activity
GO995_RS02805	COG0133	tryptophan synthase activity
GO995_RS02810	COG0159	tryptophan synthase activity
GO995_RS02815	COG1396	sequence-specific DNA binding
GO995_RS02820	COG1914	H( )-stimulated, divalent metal cation uptake system
GO995_RS02835	COG0783	Belongs to the Dps family
GO995_RS02845	COG1940	carbohydrate kinase activity
GO995_RS02850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO995_RS02890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GO995_RS02895	COG1799	cell septum assembly
GO995_RS02910	COG3599	regulation of cell shape
GO995_RS02930	COG0542	response to heat
GO995_RS02945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GO995_RS02950	COG4703	Protein of unknown function (DUF1797)
GO995_RS02955	COG0765	amino acid transport
GO995_RS02960	COG1126	abc transporter atp-binding protein
GO995_RS02970	COG1918	ferrous iron import across plasma membrane
GO995_RS02970	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GO995_RS02985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GO995_RS03015	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GO995_RS03020	COG1438	arginine binding
GO995_RS03025	COG0497	DNA recombination
GO995_RS03030	COG1307	EDD domain protein, DegV family
GO995_RS03035	COG2755	lipolytic protein G-D-S-L family
GO995_RS03040	COG4698	Protein conserved in bacteria
GO995_RS03055	COG3104	oligopeptide transport
GO995_RS03060	COG0167	dihydroorotate dehydrogenase activity
GO995_RS03065	COG0640	Transcriptional regulator
GO995_RS03070	COG2217	Heavy metal translocating P-type atpase
GO995_RS03075	COG0588	phosphoglycerate mutase activity
GO995_RS03080	COG1827	regulation of RNA biosynthetic process
GO995_RS03090	COG0768	penicillin binding
GO995_RS03095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GO995_RS03110	COG1181	Belongs to the D-alanine--D-alanine ligase family
GO995_RS03120	COG0385	Bile acid
GO995_RS03125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GO995_RS03140	COG0513	Belongs to the DEAD box helicase family
GO995_RS03150	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GO995_RS03155	COG0204	Acyl-transferase
GO995_RS03160	COG1596	polysaccharide export
GO995_RS03160	COG1555	photosystem II stabilization
GO995_RS03165	COG0658	competence protein
GO995_RS03165	COG2333	competence protein COMEC
GO995_RS03170	COG1466	dna polymerase III delta subunit
GO995_RS03180	COG0217	transcriptional regulatory protein
GO995_RS03185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GO995_RS03200	COG1187	pseudouridine synthase activity
GO995_RS03220	COG0546	phosphoglycolate phosphatase activity
GO995_RS03225	COG4122	O-methyltransferase activity
GO995_RS03230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO995_RS03235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GO995_RS03245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO995_RS03250	COG0436	Aminotransferase
GO995_RS03260	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GO995_RS03265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GO995_RS03270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GO995_RS03280	COG1476	TRANSCRIPTIONal
GO995_RS03290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO995_RS03290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO995_RS03295	COG0307	riboflavin synthase, alpha
GO995_RS03300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GO995_RS03300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GO995_RS03310	COG3859	Proton-coupled thiamine transporter YuaJ
GO995_RS03315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GO995_RS03320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GO995_RS03325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GO995_RS03330	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GO995_RS03335	COG0372	Belongs to the citrate synthase family
GO995_RS03365	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GO995_RS03400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GO995_RS03405	COG0066	3-isopropylmalate dehydratase activity
GO995_RS03410	COG1956	GAF domain-containing protein
GO995_RS03415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GO995_RS03425	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GO995_RS03425	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GO995_RS03430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GO995_RS03435	COG2207	Transcriptional regulator
GO995_RS03435	COG3708	Transcriptional regulator
GO995_RS03440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GO995_RS03445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO995_RS03450	COG4109	DRTGG domain
GO995_RS03455	COG0024	Methionine aminopeptidase
GO995_RS03465	COG2246	polysaccharide biosynthetic process
GO995_RS03470	COG4708	membrane
GO995_RS03475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GO995_RS03480	COG1597	lipid kinase activity
GO995_RS03530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GO995_RS03560	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GO995_RS03565	COG1074	ATP-dependent DNA helicase activity
GO995_RS03595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GO995_RS03610	COG0300	oxidoreductase activity
GO995_RS03615	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GO995_RS03615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GO995_RS03620	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GO995_RS03640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GO995_RS03645	COG2384	SAM-dependent methyltransferase
GO995_RS03655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GO995_RS03665	COG1088	dTDP-glucose 4,6-dehydratase activity
GO995_RS03670	COG1051	belongs to the nudix hydrolase family
GO995_RS03675	COG0628	permease
GO995_RS03680	COG0457	Tetratricopeptide repeat
GO995_RS03690	COG0028	Belongs to the TPP enzyme family
GO995_RS03695	COG3527	Alpha-acetolactate decarboxylase
GO995_RS03700	COG0531	amino acid
GO995_RS03705	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GO995_RS03710	COG0583	DNA-binding transcription factor activity
GO995_RS03715	COG1126	abc transporter atp-binding protein
GO995_RS03720	COG0765	amino acid transport
GO995_RS03730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GO995_RS03735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GO995_RS03740	COG4187	Peptidase family M20/M25/M40
GO995_RS03750	COG4120	Belongs to the binding-protein-dependent transport system permease family
GO995_RS03755	COG3842	ATPase activity
GO995_RS03775	COG0488	(ABC) transporter
GO995_RS03780	COG1396	sequence-specific DNA binding
GO995_RS03795	COG1132	(ABC) transporter
GO995_RS03800	COG1132	(ABC) transporter
GO995_RS03810	COG0640	Transcriptional regulator
GO995_RS03815	COG2814	Major facilitator Superfamily
GO995_RS03820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GO995_RS03830	COG0789	Transcriptional regulator
GO995_RS03860	COG1136	(ABC) transporter
GO995_RS03865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GO995_RS03870	COG1011	Hydrolase
GO995_RS03880	COG0583	DNA-binding transcription factor activity
GO995_RS03885	COG2855	membrane
GO995_RS03890	COG1012	belongs to the aldehyde dehydrogenase family
GO995_RS03895	COG0322	excinuclease ABC activity
GO995_RS03920	COG1573	uracil-dna glycosylase
GO995_RS03955	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GO995_RS03980	COG1316	TRANSCRIPTIONal
GO995_RS04015	COG0110	maltose O-acetyltransferase activity
GO995_RS04030	COG3475	LICD family
GO995_RS04035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GO995_RS04045	COG1091	dTDP-4-dehydrorhamnose reductase activity
GO995_RS04070	COG0167	dihydroorotate dehydrogenase activity
GO995_RS04075	COG0284	orotidine-5'-phosphate decarboxylase activity
GO995_RS04080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GO995_RS04090	COG1881	PFAM PEBP family protein
GO995_RS04115	COG0187	DNA topoisomerase II activity
GO995_RS04120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GO995_RS04125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GO995_RS04145	COG0539	negative regulation of cytoplasmic translation
GO995_RS04155	COG1346	cytolysis
GO995_RS04160	COG1380	Effector of murein hydrolase LrgA
GO995_RS04180	COG1131	(ABC) transporter
GO995_RS04185	COG1725	Transcriptional regulator
GO995_RS04195	COG0205	6-phosphofructokinase activity
GO995_RS04200	COG0469	pyruvate kinase activity
GO995_RS04215	COG2824	Alkylphosphonate utilization operon protein PhnA
GO995_RS04220	COG0765	amino acid transport
GO995_RS04225	COG1126	abc transporter atp-binding protein
GO995_RS04235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GO995_RS04240	COG1115	amino acid carrier protein
GO995_RS04245	COG2723	6-phospho-beta-galactosidase activity
GO995_RS04250	COG0406	alpha-ribazole phosphatase activity
GO995_RS04255	COG0628	permease
GO995_RS04265	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GO995_RS04275	COG1104	cysteine desulfurase activity
GO995_RS04285	COG4116	CYTH
GO995_RS04290	COG2357	RelA SpoT domain protein
GO995_RS04300	COG0564	pseudouridine synthase activity
GO995_RS04305	COG0280	phosphate acetyltransferase
GO995_RS04310	COG4221	oxidoreductase activity
GO995_RS04320	COG0561	phosphatase activity
GO995_RS04325	COG2723	6-phospho-beta-galactosidase activity
GO995_RS04330	COG1136	(ABC) transporter
GO995_RS04335	COG0577	efflux transmembrane transporter activity
GO995_RS04340	COG0516	GMP reductase activity
GO995_RS04350	COG2233	PERMEase
GO995_RS04375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GO995_RS04380	COG2890	protein-(glutamine-N5) methyltransferase activity
GO995_RS04385	COG0009	L-threonylcarbamoyladenylate synthase
GO995_RS04390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GO995_RS04410	COG1132	(ABC) transporter
GO995_RS04425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO995_RS04430	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO995_RS04430	COG0022	dehydrogenase e1 component
GO995_RS04435	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO995_RS04440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO995_RS04455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO995_RS04460	COG0095	Lipoate-protein ligase
GO995_RS04465	COG0583	DNA-binding transcription factor activity
GO995_RS04475	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GO995_RS04500	COG2814	Major facilitator Superfamily
GO995_RS04515	COG1937	Protein conserved in bacteria
GO995_RS04525	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO995_RS04530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO995_RS04535	COG1418	mRNA catabolic process
GO995_RS04545	COG0519	Catalyzes the synthesis of GMP from XMP
GO995_RS04545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GO995_RS04635	COG1396	sequence-specific DNA binding
GO995_RS04640	COG0366	Alpha amylase catalytic
GO995_RS04640	COG5263	repeat protein
GO995_RS04655	COG0534	Mate efflux family protein
GO995_RS04660	COG1461	Dihydroxyacetone kinase
GO995_RS04665	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GO995_RS04680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GO995_RS04710	COG2188	Transcriptional regulator
GO995_RS04720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GO995_RS04730	COG1132	(ABC) transporter
GO995_RS04750	COG1129	ABC transporter
GO995_RS04755	COG4974	Belongs to the 'phage' integrase family
GO995_RS04770	COG0745	RESPONSE REGULATOR receiver
GO995_RS04775	COG0577	efflux transmembrane transporter activity
GO995_RS04780	COG1136	(ABC) transporter
GO995_RS04810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GO995_RS04815	COG0758	DNA mediated transformation
GO995_RS04820	COG0110	maltose O-acetyltransferase activity
GO995_RS04825	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GO995_RS04830	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GO995_RS04885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GO995_RS04930	COG0488	(ABC) transporter
GO995_RS04945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO995_RS04950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO995_RS04955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GO995_RS04960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GO995_RS04970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GO995_RS04975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GO995_RS04980	COG4684	Psort location CytoplasmicMembrane, score
GO995_RS04985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GO995_RS05005	COG0346	lactoylglutathione lyase activity
GO995_RS05010	COG3764	Sortase (surface protein transpeptidase)
GO995_RS05045	COG1744	ABC transporter substrate-binding protein PnrA-like
GO995_RS05055	COG2813	Specifically methylates the guanine in position
GO995_RS05060	COG1072	(Pantothenic acid kinase))
GO995_RS05070	COG5002	protein histidine kinase activity
GO995_RS05075	COG0745	RESPONSE REGULATOR receiver
GO995_RS05085	COG0704	Plays a role in the regulation of phosphate uptake
GO995_RS05090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GO995_RS05095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GO995_RS05100	COG0581	inorganic phosphate transmembrane transporter activity
GO995_RS05105	COG0573	inorganic phosphate transmembrane transporter activity
GO995_RS05115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GO995_RS05115	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GO995_RS05120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO995_RS05140	COG0483	inositol monophosphate 1-phosphatase activity
GO995_RS05145	COG4476	Belongs to the UPF0223 family
GO995_RS05150	COG1393	Belongs to the ArsC family
GO995_RS05155	COG0196	riboflavin kinase activity
GO995_RS05160	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GO995_RS05190	COG0577	efflux transmembrane transporter activity
GO995_RS05190	COG1136	(ABC) transporter
GO995_RS05210	COG2873	o-acetylhomoserine
GO995_RS05220	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GO995_RS05230	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GO995_RS05275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO995_RS05280	COG1115	amino acid carrier protein
GO995_RS05285	COG0561	phosphatase activity
GO995_RS05305	COG0561	phosphatase activity
GO995_RS05310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO995_RS05320	COG1447	Phosphotransferase system cellobiose-specific component IIA
GO995_RS05325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO995_RS05325	COG3711	transcriptional antiterminator
GO995_RS05330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GO995_RS05355	COG2723	6-phospho-beta-galactosidase activity
GO995_RS05370	COG2207	Transcriptional regulator
GO995_RS05375	COG2190	(PTS) system
GO995_RS05375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO995_RS05375	COG1263	PTS System
GO995_RS05380	COG3711	transcriptional antiterminator
GO995_RS05395	COG1177	transmembrane transport
GO995_RS05400	COG1176	ABC-type spermidine putrescine transport system, permease component I
GO995_RS05410	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GO995_RS05435	COG0285	dihydrofolate synthase activity
GO995_RS05440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO995_RS05445	COG2962	Rard protein
GO995_RS05460	COG0726	polysaccharide deacetylase
GO995_RS05485	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GO995_RS05500	COG2040	homocysteine
GO995_RS05505	COG0833	amino acid
GO995_RS05525	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GO995_RS05530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GO995_RS05535	COG3425	synthase
GO995_RS05550	COG1272	protein, Hemolysin III
GO995_RS05580	COG1126	abc transporter atp-binding protein
GO995_RS05585	COG4215	(ABC) transporter
GO995_RS05595	COG1126	abc transporter atp-binding protein
GO995_RS05600	COG0765	amino acid transport
GO995_RS05605	COG0765	amino acid transport
GO995_RS05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO995_RS05620	COG0583	DNA-binding transcription factor activity
GO995_RS05625	COG0656	L-ascorbic acid biosynthetic process
GO995_RS05630	COG5002	protein histidine kinase activity
GO995_RS05635	COG0745	RESPONSE REGULATOR receiver
GO995_RS05640	COG2357	RelA SpoT domain protein
GO995_RS05645	COG1132	(ABC) transporter
GO995_RS05660	COG0242	peptide deformylase activity
GO995_RS05665	COG1247	-acetyltransferase
GO995_RS05670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GO995_RS05680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GO995_RS05685	COG0602	queuosine metabolic process
GO995_RS05690	COG0720	synthase
GO995_RS05695	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GO995_RS05700	COG1132	(ABC) transporter
GO995_RS05710	COG0488	(ABC) transporter
GO995_RS05735	COG1705	Flagellar rod assembly protein muramidase FlgJ
GO995_RS05735	COG1388	LysM domain
GO995_RS05740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GO995_RS05745	COG0646	methionine synthase
GO995_RS05745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GO995_RS05750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GO995_RS05755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO995_RS05755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO995_RS05755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO995_RS05760	COG1105	Belongs to the carbohydrate kinase PfkB family
GO995_RS05765	COG1349	DNA-binding transcription factor activity
GO995_RS05770	COG0492	ferredoxin-NADP+ reductase activity
GO995_RS05775	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GO995_RS05785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GO995_RS05800	COG1837	Belongs to the UPF0109 family
GO995_RS05820	COG0577	efflux transmembrane transporter activity
GO995_RS05825	COG1136	(ABC) transporter
GO995_RS05840	COG0505	Belongs to the CarA family
GO995_RS05845	COG0540	Belongs to the ATCase OTCase family
GO995_RS05860	COG0564	pseudouridine synthase activity
GO995_RS05870	COG0583	DNA-binding transcription factor activity
GO995_RS05875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GO995_RS05900	COG0301	tRNA thio-modification
GO995_RS05905	COG1104	cysteine desulfurase activity
GO995_RS05915	COG0285	dihydrofolate synthase activity
GO995_RS05930	COG0287	Prephenate dehydrogenase
GO995_RS05940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GO995_RS05945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GO995_RS05955	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GO995_RS05960	COG1368	sulfuric ester hydrolase activity
GO995_RS05965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GO995_RS05970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GO995_RS05975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GO995_RS05980	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GO995_RS06000	COG2195	Cleaves the N-terminal amino acid of tripeptides
GO995_RS06015	COG3942	CHAP domain
GO995_RS06020	COG0463	Glycosyl transferase, family 2
GO995_RS06045	COG3754	Rhamnan synthesis protein F
GO995_RS06065	COG1216	Glycosyl transferase, family 2
GO995_RS06065	COG1442	glycosyl transferase family 8
GO995_RS06075	COG2151	metal-sulfur cluster biosynthetic enzyme
GO995_RS06080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GO995_RS06085	COG0358	DNA primase activity
GO995_RS06090	COG1970	mechanosensitive ion channel activity
GO995_RS06110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO995_RS06120	COG0058	SHG alpha-glucan phosphorylase activity
GO995_RS06125	COG1640	4-alpha-glucanotransferase
GO995_RS06130	COG1609	Transcriptional regulator
GO995_RS06140	COG1175	transmembrane transport
GO995_RS06145	COG3833	ABC-type maltose transport systems, permease component
GO995_RS06150	COG2816	NAD+ diphosphatase activity
GO995_RS06165	COG1126	abc transporter atp-binding protein
GO995_RS06170	COG1592	Rubrerythrin
GO995_RS06175	COG0488	(ABC) transporter
GO995_RS06195	COG1187	pseudouridine synthase activity
GO995_RS06200	COG4166	transmembrane transport
GO995_RS06205	COG4166	transmembrane transport
GO995_RS06210	COG0659	secondary active sulfate transmembrane transporter activity
GO995_RS06220	COG0590	tRNA wobble adenosine to inosine editing
GO995_RS06240	COG0454	-acetyltransferase
GO995_RS06245	COG0456	acetyltransferase
GO995_RS06260	COG2211	Major facilitator Superfamily
GO995_RS06270	COG1396	sequence-specific DNA binding
GO995_RS06310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GO995_RS06335	COG1396	sequence-specific DNA binding
GO995_RS06340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO995_RS06345	COG1316	TRANSCRIPTIONal
GO995_RS06350	COG0077	Prephenate dehydratase
GO995_RS06355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GO995_RS06360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GO995_RS06365	COG0481	GTPase activity
GO995_RS06380	COG1518	maintenance of DNA repeat elements
GO995_RS06410	COG0647	UMP catabolic process
GO995_RS06420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GO995_RS06435	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GO995_RS06440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GO995_RS06445	COG3442	glutamine amidotransferase
GO995_RS06450	COG0148	phosphopyruvate hydratase activity
GO995_RS06465	COG1523	belongs to the glycosyl hydrolase 13 family
GO995_RS06480	COG0107	imidazoleglycerol-phosphate synthase activity
GO995_RS06490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GO995_RS06500	COG0560	Phosphoserine phosphatase
GO995_RS06505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GO995_RS06515	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GO995_RS06530	COG0187	DNA topoisomerase II activity
GO995_RS06540	COG0772	Belongs to the SEDS family
GO995_RS06555	COG0038	chloride channel
GO995_RS06565	COG0398	Pfam SNARE associated Golgi protein
GO995_RS06575	COG0716	FMN binding
GO995_RS06585	COG1454	alcohol dehydrogenase
GO995_RS06590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GO995_RS06600	COG1388	LysM domain
GO995_RS06600	COG1705	Flagellar rod assembly protein muramidase FlgJ
GO995_RS06625	COG1660	Displays ATPase and GTPase activities
GO995_RS06635	COG1309	transcriptional regulator
GO995_RS06650	COG0251	oxidation-reduction process
GO995_RS06670	COG0017	Asparaginyl-tRNA synthetase
GO995_RS06680	COG0436	Aminotransferase
GO995_RS06690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO995_RS06690	COG1199	ATP-dependent helicase activity
GO995_RS06705	COG2177	Part of the ABC transporter FtsEX involved in
GO995_RS06710	COG2884	Cell division ATP-binding protein ftsE
GO995_RS06720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO995_RS06740	COG1078	dGTPase activity
GO995_RS06765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GO995_RS06770	COG0772	Belongs to the SEDS family
GO995_RS06780	COG1164	Oligoendopeptidase f
GO995_RS06785	COG0386	Belongs to the glutathione peroxidase family
GO995_RS06805	COG0588	phosphoglycerate mutase activity
GO995_RS06815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GO995_RS06830	COG1309	transcriptional regulator
GO995_RS06840	COG4443	Transcriptional Coactivator p15 (PC4)
GO995_RS06890	COG3091	SprT-like family
GO995_RS06895	COG2183	response to ionizing radiation
GO995_RS06905	COG0701	Predicted permease
GO995_RS06910	COG3689	TIGRFAM TIGR03943 family protein
GO995_RS06920	COG0552	protein localization to endoplasmic reticulum
GO995_RS06925	COG0561	phosphatase activity
GO995_RS06930	COG0561	phosphatase activity
GO995_RS06940	COG1196	nuclear chromosome segregation
GO995_RS06950	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GO995_RS06955	COG5002	protein histidine kinase activity
GO995_RS06960	COG0745	RESPONSE REGULATOR receiver
GO995_RS06965	COG1126	abc transporter atp-binding protein
GO995_RS06970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO995_RS06975	COG0765	amino acid transport
GO995_RS06980	COG0765	amino acid transport
GO995_RS06995	COG3850	Histidine kinase
GO995_RS06995	COG5002	protein histidine kinase activity
GO995_RS07000	COG0745	RESPONSE REGULATOR receiver
GO995_RS07005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GO995_RS07020	COG4716	Myosin-crossreactive antigen
GO995_RS07030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GO995_RS07035	COG0438	transferase activity, transferring glycosyl groups
GO995_RS07045	COG1609	Transcriptional regulator
GO995_RS07050	COG0006	proline dipeptidase activity
GO995_RS07055	COG2816	NAD+ diphosphatase activity
GO995_RS07060	COG0583	DNA-binding transcription factor activity
GO995_RS07065	COG1811	Na channel or pump
GO995_RS07080	COG0778	Nitroreductase
GO995_RS07095	COG1846	Transcriptional regulator
GO995_RS07105	COG0557	exoribonuclease II activity
GO995_RS07120	COG2814	Major facilitator Superfamily
GO995_RS07125	COG0237	dephospho-CoA kinase activity
GO995_RS07130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GO995_RS07140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GO995_RS07145	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GO995_RS07150	COG0366	Alpha amylase catalytic
GO995_RS07170	COG1702	phosphate starvation-inducible protein PhoH
GO995_RS07175	COG4479	Belongs to the UPF0346 family
GO995_RS07185	COG2996	Protein conserved in bacteria
GO995_RS07215	COG1674	ftsk spoiiie
GO995_RS07245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GO995_RS07260	COG1028	Short-chain dehydrogenase reductase Sdr
GO995_RS07275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO995_RS07275	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO995_RS07290	COG0640	Transcriptional regulator
GO995_RS07295	COG0708	Exodeoxyribonuclease III
GO995_RS07305	COG1136	(ABC) transporter
GO995_RS07315	COG2197	response regulator
GO995_RS07325	COG1393	Belongs to the ArsC family
GO995_RS07330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GO995_RS07360	COG1902	pentaerythritol trinitrate reductase activity
GO995_RS07375	COG0004	ammonium transporteR
GO995_RS07390	COG1774	PSP1 C-terminal conserved region
GO995_RS07395	COG0470	DNA polymerase III
GO995_RS07405	COG0517	IMP dehydrogenase activity
GO995_RS07405	COG1227	inorganic diphosphatase activity
GO995_RS07435	COG4471	UPF0298 protein
GO995_RS07455	COG0583	DNA-binding transcription factor activity
GO995_RS07465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GO995_RS07470	COG0626	cystathionine gamma-synthase activity
GO995_RS07475	COG2244	polysaccharide biosynthetic process
GO995_RS07485	COG1120	ATPase activity
GO995_RS07490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GO995_RS07495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO995_RS07500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO995_RS07515	COG3022	response to hydroperoxide
GO995_RS07540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GO995_RS07545	COG1253	flavin adenine dinucleotide binding
GO995_RS07550	COG2190	(PTS) system
GO995_RS07550	COG2211	Major facilitator Superfamily
GO995_RS07555	COG1119	ATPase activity
GO995_RS07560	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GO995_RS07565	COG1242	4 iron, 4 sulfur cluster binding
GO995_RS07570	COG0671	phosphoesterase, PA-phosphatase related
GO995_RS07575	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GO995_RS07585	COG0531	amino acid
GO995_RS07590	COG0569	domain protein
GO995_RS07595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO995_RS07600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GO995_RS07605	COG1187	pseudouridine synthase activity
GO995_RS07620	COG0582	viral genome integration into host DNA
GO995_RS07640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GO995_RS07645	COG3763	UPF0154 protein
GO995_RS07665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO995_RS07670	COG1254	Belongs to the acylphosphatase family
GO995_RS07685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GO995_RS07715	COG1484	DNA-dependent DNA replication
GO995_RS07730	COG5002	protein histidine kinase activity
GO995_RS07735	COG0745	RESPONSE REGULATOR receiver
GO995_RS07745	COG0501	Belongs to the peptidase M48B family
GO995_RS07750	COG1704	LemA family
GO995_RS07760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO995_RS07775	COG1122	ATPase activity
GO995_RS07785	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GO995_RS07790	COG1114	Component of the transport system for branched-chain amino acids
GO995_RS07795	COG2910	NAD(P)H-binding
GO995_RS07800	COG1959	2 iron, 2 sulfur cluster binding
GO995_RS07820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO995_RS07825	COG1473	amidohydrolase
GO995_RS07830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO995_RS07835	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GO995_RS07840	COG0217	transcriptional regulatory protein
GO995_RS07845	COG0789	Transcriptional regulator
GO995_RS07855	COG2226	methyltransferase
GO995_RS07860	COG0799	negative regulation of ribosome biogenesis
GO995_RS07870	COG1713	HD superfamily hydrolase involved in NAD metabolism
GO995_RS07875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GO995_RS07880	COG1534	Rna-binding protein
GO995_RS07885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GO995_RS07890	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GO995_RS07895	COG0477	Major facilitator Superfamily
GO995_RS07915	COG0154	amidase activity
GO995_RS07920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GO995_RS07925	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GO995_RS07930	COG0436	Aminotransferase
GO995_RS07940	COG0589	response to stress
GO995_RS07945	COG0561	phosphatase activity
GO995_RS07950	COG0252	asparaginase activity
GO995_RS07965	COG3655	Transcriptional regulator
GO995_RS07985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GO995_RS08000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO995_RS08005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO995_RS08015	COG1940	carbohydrate kinase activity
GO995_RS08020	COG1263	PTS System
GO995_RS08020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO995_RS08020	COG2190	(PTS) system
GO995_RS08025	COG1621	beta-fructofuranosidase activity
GO995_RS08030	COG1609	Transcriptional regulator
GO995_RS08035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GO995_RS08045	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GO995_RS08055	COG2131	deaminase
GO995_RS08060	COG0006	proline dipeptidase activity
GO995_RS08090	COG3655	Transcriptional regulator
GO995_RS08100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GO995_RS08135	COG0681	Belongs to the peptidase S26 family
GO995_RS08145	COG1194	a g-specific adenine glycosylase
GO995_RS08175	COG3118	belongs to the thioredoxin family
GO995_RS08185	COG0157	Belongs to the NadC ModD family
GO995_RS08195	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GO995_RS08205	COG1132	(ABC) transporter
GO995_RS08210	COG1193	negative regulation of DNA recombination
GO995_RS08225	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GO995_RS08230	COG0681	Belongs to the peptidase S26 family
GO995_RS08235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GO995_RS08250	COG1882	Formate acetyltransferase
GO995_RS08265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GO995_RS08285	COG5002	protein histidine kinase activity
GO995_RS08290	COG0745	RESPONSE REGULATOR receiver
GO995_RS08295	COG0704	Plays a role in the regulation of phosphate uptake
GO995_RS08300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GO995_RS08305	COG0581	inorganic phosphate transmembrane transporter activity
GO995_RS08310	COG0573	inorganic phosphate transmembrane transporter activity
GO995_RS08325	COG0789	Transcriptional regulator
GO995_RS08340	COG2081	HI0933 family
GO995_RS08355	COG0456	acetyltransferase
GO995_RS08360	COG1214	PFAM Peptidase M22, glycoprotease
GO995_RS08375	COG3942	CHAP domain
GO995_RS08380	COG0493	'glutamate synthase
GO995_RS08385	COG0067	glutamate synthase
GO995_RS08385	COG0069	glutamate synthase activity
GO995_RS08385	COG0070	glutamate synthase
GO995_RS08390	COG0174	glutamine synthetase
GO995_RS08395	COG0789	Transcriptional regulator
GO995_RS08405	COG0126	phosphoglycerate kinase activity
GO995_RS08410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO995_RS08415	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GO995_RS08420	COG0049	tRNA binding
GO995_RS08430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GO995_RS08450	COG1564	THIamine pyrophosphokinase
GO995_RS08455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GO995_RS08480	COG3290	protein histidine kinase activity
GO995_RS08545	COG2274	protein secretion by the type I secretion system
GO995_RS08550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO995_RS08560	COG1266	CAAX protease self-immunity
GO995_RS08595	COG0084	hydrolase, TatD family'
GO995_RS08600	COG1132	(ABC) transporter
GO995_RS08605	COG2223	nitrite transmembrane transporter activity
GO995_RS08615	COG0281	malic enzyme
GO995_RS08620	COG0583	DNA-binding transcription factor activity
GO995_RS08625	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GO995_RS08630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO995_RS08635	COG1696	Membrane protein involved in D-alanine export
GO995_RS08650	COG5002	protein histidine kinase activity
GO995_RS08655	COG0745	RESPONSE REGULATOR receiver
GO995_RS08660	COG2207	Transcriptional regulator
GO995_RS08665	COG2273	Hydrolase Family 16
GO995_RS08675	COG0395	ABC-type sugar transport system, permease component
GO995_RS08700	COG2273	Hydrolase Family 16
GO995_RS08730	COG1131	(ABC) transporter
GO995_RS08745	COG0594	ribonuclease P activity
GO995_RS08755	COG0137	argininosuccinate synthase activity
GO995_RS08765	COG0444	Belongs to the ABC transporter superfamily
GO995_RS08770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO995_RS08775	COG0601	transmembrane transport
GO995_RS08780	COG4166	transmembrane transport
GO995_RS08785	COG2807	transmembrane transport
GO995_RS08790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO995_RS08800	COG4989	oxidoreductase activity
GO995_RS08815	COG0756	dUTP diphosphatase activity
GO995_RS08830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GO995_RS08840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GO995_RS08845	COG1473	amidohydrolase
GO995_RS08850	COG2171	N-acyltransferase activity
GO995_RS08875	COG0166	Belongs to the GPI family
GO995_RS08890	COG1234	tRNA 3'-trailer cleavage
GO995_RS08895	COG1268	BioY protein
GO995_RS08905	COG0343	queuine tRNA-ribosyltransferase activity
GO995_RS08920	COG1832	CoA-binding protein
GO995_RS08925	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO995_RS08925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO995_RS08945	COG0697	spore germination
GO995_RS08960	COG1181	Belongs to the D-alanine--D-alanine ligase family
GO995_RS08960	COG2918	glutathione biosynthetic process
GO995_RS08975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GO995_RS08980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO995_RS08990	COG1131	(ABC) transporter
GO995_RS09000	COG3290	protein histidine kinase activity
GO995_RS09005	COG3290	protein histidine kinase activity
GO995_RS09015	COG3279	Response regulator of the LytR AlgR family
GO995_RS09025	COG0542	response to heat
GO995_RS09030	COG4463	regulation of RNA biosynthetic process
GO995_RS09055	COG1619	proteins homologs of microcin C7 resistance protein MccF
GO995_RS09085	COG1396	sequence-specific DNA binding
GO995_RS09090	COG3590	peptidase
GO995_RS09120	COG1309	transcriptional regulator
GO995_RS09125	COG0602	queuosine metabolic process
GO995_RS09135	COG1328	CTP reductase activity
GO995_RS09135	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GO995_RS09155	COG4472	Bacterial protein of unknown function (DUF965)
GO995_RS09160	COG1393	Belongs to the ArsC family
GO995_RS09170	COG1058	Belongs to the CinA family
GO995_RS09170	COG1546	Belongs to the CinA family
GO995_RS09180	COG0519	Catalyzes the synthesis of GMP from XMP
GO995_RS09225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GO995_RS09230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GO995_RS09255	COG3843	relaxase mobilization nuclease domain protein
GO995_RS09290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GO995_RS09290	COG0551	DNA topoisomerase type I activity
GO995_RS09320	COG0629	single-stranded DNA binding
GO995_RS09395	COG3177	Filamentation induced by cAMP protein fic
GO995_RS09420	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs