locus-tag	class	description
A6J31_RS00065	COG1136	(ABC) transporter
A6J31_RS00070	COG0577	efflux transmembrane transporter activity
A6J31_RS00090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A6J31_RS00140	COG1396	sequence-specific DNA binding
A6J31_RS00145	COG2226	methyltransferase
A6J31_RS00250	COG4974	Belongs to the 'phage' integrase family
A6J31_RS00370	COG3290	protein histidine kinase activity
A6J31_RS00375	COG3279	Response regulator of the LytR AlgR family
A6J31_RS00390	COG2274	protein secretion by the type I secretion system
A6J31_RS00515	COG2205	protein histidine kinase activity
A6J31_RS00520	COG0745	RESPONSE REGULATOR receiver
A6J31_RS00550	COG0494	nUDIX hydrolase
A6J31_RS00560	COG1373	ATPase (AAA superfamily
A6J31_RS00570	COG3655	Transcriptional regulator
A6J31_RS00595	COG1132	(ABC) transporter
A6J31_RS00625	COG1136	(ABC) transporter
A6J31_RS00640	COG2197	response regulator
A6J31_RS00685	COG3279	Response regulator of the LytR AlgR family
A6J31_RS00730	COG0577	efflux transmembrane transporter activity
A6J31_RS00730	COG1136	(ABC) transporter
A6J31_RS00745	COG1247	-acetyltransferase
A6J31_RS00765	COG0542	response to heat
A6J31_RS00785	COG1280	lysine exporter protein (LysE YggA)
A6J31_RS00825	COG2184	nucleotidyltransferase activity
A6J31_RS00860	COG1131	(ABC) transporter
A6J31_RS00935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A6J31_RS00975	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A6J31_RS01105	COG0488	(ABC) transporter
A6J31_RS01125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A6J31_RS01135	COG0242	peptide deformylase activity
A6J31_RS01160	COG2357	RelA SpoT domain protein
A6J31_RS01165	COG0745	RESPONSE REGULATOR receiver
A6J31_RS01200	COG1702	phosphate starvation-inducible protein PhoH
A6J31_RS01220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J31_RS01220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J31_RS01225	COG0656	L-ascorbic acid biosynthetic process
A6J31_RS01230	COG0583	DNA-binding transcription factor activity
A6J31_RS01255	COG2223	nitrite transmembrane transporter activity
A6J31_RS01260	COG4122	O-methyltransferase activity
A6J31_RS01265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6J31_RS01315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A6J31_RS01320	COG0436	Aminotransferase
A6J31_RS01330	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A6J31_RS01335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A6J31_RS01340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A6J31_RS01345	COG0726	polysaccharide deacetylase
A6J31_RS01360	COG2962	Rard protein
A6J31_RS01395	COG0519	Catalyzes the synthesis of GMP from XMP
A6J31_RS01420	COG0356	it plays a direct role in the translocation of protons across the membrane
A6J31_RS01455	COG0772	Belongs to the SEDS family
A6J31_RS01465	COG0149	triose-phosphate isomerase activity
A6J31_RS01485	COG0470	DNA polymerase III
A6J31_RS01490	COG1774	PSP1 C-terminal conserved region
A6J31_RS01495	COG4467	Involved in initiation control of chromosome replication
A6J31_RS01505	COG0004	ammonium transporteR
A6J31_RS01510	COG0347	Belongs to the P(II) protein family
A6J31_RS01515	COG1388	LysM domain
A6J31_RS01515	COG1705	Flagellar rod assembly protein muramidase FlgJ
A6J31_RS01535	COG1283	sodium-dependent phosphate transmembrane transporter activity
A6J31_RS01565	COG1113	amino acid transport
A6J31_RS01575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J31_RS01575	COG1263	PTS System
A6J31_RS01575	COG2190	(PTS) system
A6J31_RS01625	COG0564	pseudouridine synthase activity
A6J31_RS01645	COG0505	Belongs to the CarA family
A6J31_RS01665	COG1136	(ABC) transporter
A6J31_RS01670	COG0577	efflux transmembrane transporter activity
A6J31_RS01700	COG1132	(ABC) transporter
A6J31_RS01720	COG3279	Response regulator of the LytR AlgR family
A6J31_RS01725	COG1131	(ABC) transporter
A6J31_RS01760	COG1187	pseudouridine synthase activity
A6J31_RS01765	COG1473	amidohydrolase
A6J31_RS01770	COG0686	Belongs to the AlaDH PNT family
A6J31_RS01780	COG2267	carboxylic ester hydrolase activity
A6J31_RS01795	COG3850	Histidine kinase
A6J31_RS01795	COG5002	protein histidine kinase activity
A6J31_RS01800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J31_RS01835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A6J31_RS01870	COG0438	transferase activity, transferring glycosyl groups
A6J31_RS01885	COG0596	Alpha beta hydrolase
A6J31_RS01900	COG1272	protein, Hemolysin III
A6J31_RS01915	COG3425	synthase
A6J31_RS01925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A6J31_RS01940	COG0833	amino acid
A6J31_RS01945	COG2040	homocysteine
A6J31_RS01965	COG0187	DNA topoisomerase II activity
A6J31_RS01985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6J31_RS02005	COG0539	negative regulation of cytoplasmic translation
A6J31_RS02045	COG0494	nUDIX hydrolase
A6J31_RS02050	COG0542	response to heat
A6J31_RS02055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A6J31_RS02060	COG4703	Protein of unknown function (DUF1797)
A6J31_RS02065	COG0765	amino acid transport
A6J31_RS02070	COG1126	abc transporter atp-binding protein
A6J31_RS02100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A6J31_RS02105	COG0768	penicillin binding
A6J31_RS02110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A6J31_RS02125	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A6J31_RS02130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A6J31_RS02135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A6J31_RS02140	COG0237	dephospho-CoA kinase activity
A6J31_RS02145	COG2814	Major facilitator Superfamily
A6J31_RS02160	COG0557	exoribonuclease II activity
A6J31_RS02175	COG1185	polyribonucleotide nucleotidyltransferase activity
A6J31_RS02180	COG0006	proline dipeptidase activity
A6J31_RS02185	COG1609	Transcriptional regulator
A6J31_RS02215	COG1368	sulfuric ester hydrolase activity
A6J31_RS02220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A6J31_RS02245	COG0287	Prephenate dehydrogenase
A6J31_RS02260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A6J31_RS02270	COG0077	Prephenate dehydratase
A6J31_RS02300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A6J31_RS02305	COG2226	methyltransferase
A6J31_RS02320	COG1131	(ABC) transporter
A6J31_RS02345	COG0135	phosphoribosylanthranilate isomerase activity
A6J31_RS02370	COG0488	(ABC) transporter
A6J31_RS02425	COG1131	(ABC) transporter
A6J31_RS02430	COG1132	(ABC) transporter
A6J31_RS02450	COG0640	Transcriptional regulator
A6J31_RS02455	COG2217	Heavy metal translocating P-type atpase
A6J31_RS02470	COG2807	transmembrane transport
A6J31_RS02475	COG1307	EDD domain protein, DegV family
A6J31_RS02485	COG3142	Participates in the control of copper homeostasis
A6J31_RS02500	COG0477	Major facilitator Superfamily
A6J31_RS02525	COG1120	ATPase activity
A6J31_RS02535	COG2819	hydrolase of the alpha beta superfamily
A6J31_RS02540	COG1597	lipid kinase activity
A6J31_RS02550	COG2261	transglycosylase associated protein
A6J31_RS02555	COG3237	CsbD-like
A6J31_RS02560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J31_RS02565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A6J31_RS02570	COG0022	dehydrogenase e1 component
A6J31_RS02575	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J31_RS02580	COG2226	methyltransferase
A6J31_RS02645	COG0659	secondary active sulfate transmembrane transporter activity
A6J31_RS02650	COG3689	TIGRFAM TIGR03943 family protein
A6J31_RS02655	COG0701	Predicted permease
A6J31_RS02660	COG2183	response to ionizing radiation
A6J31_RS02680	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A6J31_RS02705	COG0826	peptidase U32
A6J31_RS02715	COG1268	BioY protein
A6J31_RS02725	COG4443	Transcriptional Coactivator p15 (PC4)
A6J31_RS02730	COG1914	H( )-stimulated, divalent metal cation uptake system
A6J31_RS02740	COG0494	nUDIX hydrolase
A6J31_RS02760	COG1705	Flagellar rod assembly protein muramidase FlgJ
A6J31_RS02760	COG1388	LysM domain
A6J31_RS02780	COG0406	alpha-ribazole phosphatase activity
A6J31_RS02785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A6J31_RS02800	COG0561	phosphatase activity
A6J31_RS02815	COG4221	oxidoreductase activity
A6J31_RS02845	COG1704	LemA family
A6J31_RS02850	COG0501	Belongs to the peptidase M48B family
A6J31_RS02885	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A6J31_RS02895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A6J31_RS02910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A6J31_RS02915	COG0783	Belongs to the Dps family
A6J31_RS02920	COG0735	belongs to the Fur family
A6J31_RS02925	COG4483	Protein conserved in bacteria
A6J31_RS02930	COG1940	carbohydrate kinase activity
A6J31_RS02935	COG1217	gtp-binding protein TYPA
A6J31_RS02960	COG0849	cell division
A6J31_RS02970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A6J31_RS02980	COG0762	integral membrane protein
A6J31_RS02990	COG3599	regulation of cell shape
A6J31_RS03000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6J31_RS03005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6J31_RS03010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A6J31_RS03015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A6J31_RS03020	COG0372	Belongs to the citrate synthase family
A6J31_RS03060	COG0513	Belongs to the DEAD box helicase family
A6J31_RS03070	COG0488	(ABC) transporter
A6J31_RS03085	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A6J31_RS03085	COG0392	lysyltransferase activity
A6J31_RS03090	COG3442	glutamine amidotransferase
A6J31_RS03095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A6J31_RS03120	COG2384	SAM-dependent methyltransferase
A6J31_RS03135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J31_RS03145	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A6J31_RS03155	COG1088	dTDP-glucose 4,6-dehydratase activity
A6J31_RS03170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6J31_RS03180	COG0647	UMP catabolic process
A6J31_RS03220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A6J31_RS03230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A6J31_RS03280	COG0366	Alpha amylase catalytic
A6J31_RS03280	COG5263	repeat protein
A6J31_RS03285	COG0366	Alpha amylase catalytic
A6J31_RS03285	COG5263	repeat protein
A6J31_RS03295	COG0632	four-way junction helicase activity
A6J31_RS03300	COG0519	Catalyzes the synthesis of GMP from XMP
A6J31_RS03315	COG0366	Alpha amylase catalytic
A6J31_RS03315	COG5263	repeat protein
A6J31_RS03320	COG0772	Belongs to the SEDS family
A6J31_RS03325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A6J31_RS03340	COG0300	oxidoreductase activity
A6J31_RS03345	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A6J31_RS03345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A6J31_RS03365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A6J31_RS03390	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A6J31_RS03395	COG1438	arginine binding
A6J31_RS03400	COG0497	DNA recombination
A6J31_RS03410	COG2755	lipolytic protein G-D-S-L family
A6J31_RS03420	COG0776	regulation of translation
A6J31_RS03430	COG0167	dihydroorotate dehydrogenase activity
A6J31_RS03435	COG0588	phosphoglycerate mutase activity
A6J31_RS03455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A6J31_RS03460	COG0066	3-isopropylmalate dehydratase activity
A6J31_RS03475	COG0469	pyruvate kinase activity
A6J31_RS03500	COG3842	ATPase activity
A6J31_RS03525	COG0716	FMN binding
A6J31_RS03540	COG0038	chloride channel
A6J31_RS03545	COG0335	large ribosomal subunit rRNA binding
A6J31_RS03565	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A6J31_RS03570	COG1956	GAF domain-containing protein
A6J31_RS03575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A6J31_RS03585	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A6J31_RS03585	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A6J31_RS03590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A6J31_RS03640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6J31_RS03665	COG0765	amino acid transport
A6J31_RS03670	COG0765	amino acid transport
A6J31_RS03675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS03680	COG1126	abc transporter atp-binding protein
A6J31_RS03685	COG0765	amino acid transport
A6J31_RS03690	COG0765	amino acid transport
A6J31_RS03695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS03700	COG1126	abc transporter atp-binding protein
A6J31_RS03705	COG0745	RESPONSE REGULATOR receiver
A6J31_RS03710	COG5002	protein histidine kinase activity
A6J31_RS03715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A6J31_RS03720	COG2832	Protein of unknown function (DUF454)
A6J31_RS03725	COG2348	transferase activity, transferring amino-acyl groups
A6J31_RS03750	COG0778	Nitroreductase
A6J31_RS03760	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A6J31_RS03765	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A6J31_RS03770	COG2884	Cell division ATP-binding protein ftsE
A6J31_RS03775	COG2177	Part of the ABC transporter FtsEX involved in
A6J31_RS03780	COG1051	belongs to the nudix hydrolase family
A6J31_RS03785	COG0628	permease
A6J31_RS03800	COG1705	Flagellar rod assembly protein muramidase FlgJ
A6J31_RS03830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A6J31_RS03835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A6J31_RS03865	COG1573	uracil-dna glycosylase
A6J31_RS03885	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A6J31_RS03895	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A6J31_RS03915	COG0813	purine-nucleoside phosphorylase activity
A6J31_RS03920	COG1316	TRANSCRIPTIONal
A6J31_RS03950	COG0297	glycogen (starch) synthase activity
A6J31_RS03960	COG1216	Glycosyl transferase, family 2
A6J31_RS03960	COG1442	glycosyl transferase family 8
A6J31_RS03970	COG0438	transferase activity, transferring glycosyl groups
A6J31_RS03995	COG0561	phosphatase activity
A6J31_RS04010	COG0588	phosphoglycerate mutase activity
A6J31_RS04015	COG0628	permease
A6J31_RS04040	COG4667	esterase of the alpha-beta hydrolase superfamily
A6J31_RS04055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A6J31_RS04085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A6J31_RS04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J31_RS04090	COG0022	dehydrogenase e1 component
A6J31_RS04095	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J31_RS04110	COG0860	N-Acetylmuramoyl-L-alanine amidase
A6J31_RS04115	COG1523	belongs to the glycosyl hydrolase 13 family
A6J31_RS04120	COG2822	iron ion transport
A6J31_RS04125	COG2837	iron assimilation
A6J31_RS04130	COG0672	)-iron permease
A6J31_RS04135	COG0805	protein transport
A6J31_RS04140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A6J31_RS04150	COG3842	ATPase activity
A6J31_RS04155	COG3833	ABC-type maltose transport systems, permease component
A6J31_RS04160	COG1175	transmembrane transport
A6J31_RS04170	COG1609	Transcriptional regulator
A6J31_RS04175	COG1640	4-alpha-glucanotransferase
A6J31_RS04180	COG0058	SHG alpha-glucan phosphorylase activity
A6J31_RS04190	COG0095	Lipoate-protein ligase
A6J31_RS04205	COG0704	Plays a role in the regulation of phosphate uptake
A6J31_RS04220	COG0581	inorganic phosphate transmembrane transporter activity
A6J31_RS04225	COG0573	inorganic phosphate transmembrane transporter activity
A6J31_RS04235	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6J31_RS04235	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A6J31_RS04240	COG0483	inositol monophosphate 1-phosphatase activity
A6J31_RS04250	COG1393	Belongs to the ArsC family
A6J31_RS04255	COG0196	riboflavin kinase activity
A6J31_RS04260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A6J31_RS04290	COG2873	o-acetylhomoserine
A6J31_RS04295	COG0210	DNA helicase
A6J31_RS04300	COG1115	amino acid carrier protein
A6J31_RS04310	COG1917	Cupin 2, conserved barrel domain protein
A6J31_RS04310	COG2207	Transcriptional regulator
A6J31_RS04315	COG0737	Belongs to the 5'-nucleotidase family
A6J31_RS04320	COG0765	amino acid transport
A6J31_RS04325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS04340	COG0284	orotidine-5'-phosphate decarboxylase activity
A6J31_RS04350	COG0167	dihydroorotate dehydrogenase activity
A6J31_RS04375	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A6J31_RS04385	COG0534	Mate efflux family protein
A6J31_RS04390	COG4607	ABC-type enterochelin transport system periplasmic component
A6J31_RS04470	COG1063	alcohol dehydrogenase
A6J31_RS04480	COG1230	cation diffusion facilitator family transporter
A6J31_RS04505	COG0596	Alpha beta hydrolase
A6J31_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
A6J31_RS04510	COG3321	synthase
A6J31_RS04510	COG0604	alcohol dehydrogenase
A6J31_RS04520	COG3201	nicotinamide mononucleotide transporter
A6J31_RS04525	COG1122	ATPase activity
A6J31_RS04535	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A6J31_RS04555	COG0577	efflux transmembrane transporter activity
A6J31_RS04555	COG1136	(ABC) transporter
A6J31_RS04565	COG2801	Transposase and inactivated derivatives
A6J31_RS04575	COG1174	glycine betaine transport
A6J31_RS04590	COG1846	Transcriptional regulator
A6J31_RS04610	COG3527	Alpha-acetolactate decarboxylase
A6J31_RS04615	COG0028	Belongs to the TPP enzyme family
A6J31_RS04680	COG1131	(ABC) transporter
A6J31_RS04685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A6J31_RS04690	COG0758	DNA mediated transformation
A6J31_RS04695	COG1940	carbohydrate kinase activity
A6J31_RS04705	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A6J31_RS04715	COG1827	regulation of RNA biosynthetic process
A6J31_RS04725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6J31_RS04735	COG2188	Transcriptional regulator
A6J31_RS04740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A6J31_RS04740	COG0519	Catalyzes the synthesis of GMP from XMP
A6J31_RS04750	COG1064	alcohol dehydrogenase
A6J31_RS04765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A6J31_RS04770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS04775	COG1126	abc transporter atp-binding protein
A6J31_RS04780	COG0765	amino acid transport
A6J31_RS04785	COG2824	Alkylphosphonate utilization operon protein PhnA
A6J31_RS04790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A6J31_RS04795	COG0583	DNA-binding transcription factor activity
A6J31_RS04800	COG1388	LysM domain
A6J31_RS04800	COG1705	Flagellar rod assembly protein muramidase FlgJ
A6J31_RS04820	COG3443	Belongs to the bacterial solute-binding protein 9 family
A6J31_RS04820	COG0803	Belongs to the bacterial solute-binding protein 9 family
A6J31_RS04880	COG0251	oxidation-reduction process
A6J31_RS04890	COG0017	Asparaginyl-tRNA synthetase
A6J31_RS04895	COG0436	Aminotransferase
A6J31_RS04905	COG1199	ATP-dependent helicase activity
A6J31_RS04905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A6J31_RS04915	COG1079	Belongs to the binding-protein-dependent transport system permease family
A6J31_RS04920	COG4603	Belongs to the binding-protein-dependent transport system permease family
A6J31_RS04925	COG3845	ABC transporter
A6J31_RS04930	COG1744	ABC transporter substrate-binding protein PnrA-like
A6J31_RS04935	COG0295	cytidine deaminase activity
A6J31_RS04940	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A6J31_RS04945	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A6J31_RS04950	COG2813	Specifically methylates the guanine in position
A6J31_RS04965	COG5002	protein histidine kinase activity
A6J31_RS04970	COG0745	RESPONSE REGULATOR receiver
A6J31_RS04985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A6J31_RS04990	COG4684	Psort location CytoplasmicMembrane, score
A6J31_RS04995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A6J31_RS05020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A6J31_RS05025	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A6J31_RS05035	COG1696	Membrane protein involved in D-alanine export
A6J31_RS05050	COG1132	(ABC) transporter
A6J31_RS05075	COG0009	L-threonylcarbamoyladenylate synthase
A6J31_RS05080	COG2890	protein-(glutamine-N5) methyltransferase activity
A6J31_RS05090	COG1435	thymidine kinase activity
A6J31_RS05095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A6J31_RS05100	COG0625	glutathione transferase activity
A6J31_RS05105	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A6J31_RS05130	COG0346	lactoylglutathione lyase activity
A6J31_RS05135	COG3764	Sortase (surface protein transpeptidase)
A6J31_RS05155	COG0488	(ABC) transporter
A6J31_RS05180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J31_RS05185	COG1328	CTP reductase activity
A6J31_RS05185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A6J31_RS05225	COG1196	nuclear chromosome segregation
A6J31_RS05240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A6J31_RS05250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J31_RS05255	COG1247	-acetyltransferase
A6J31_RS05260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J31_RS05270	COG1011	Hydrolase
A6J31_RS05275	COG1760	l-serine dehydratase
A6J31_RS05280	COG1760	l-serine dehydratase
A6J31_RS05285	COG1621	beta-fructofuranosidase activity
A6J31_RS05285	COG3583	domain protein
A6J31_RS05285	COG5492	domain, Protein
A6J31_RS05290	COG0697	spore germination
A6J31_RS05360	COG2197	response regulator
A6J31_RS05365	COG4585	Histidine kinase
A6J31_RS05375	COG1131	(ABC) transporter
A6J31_RS05390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J31_RS05400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J31_RS05405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6J31_RS05445	COG0443	Heat shock 70 kDa protein
A6J31_RS05450	COG0385	Bile acid
A6J31_RS05460	COG0842	Transport permease protein
A6J31_RS05465	COG1131	(ABC) transporter
A6J31_RS05485	COG0577	efflux transmembrane transporter activity
A6J31_RS05490	COG1136	(ABC) transporter
A6J31_RS05500	COG0745	RESPONSE REGULATOR receiver
A6J31_RS05510	COG2233	PERMEase
A6J31_RS05515	COG0534	Mate efflux family protein
A6J31_RS05525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J31_RS05525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J31_RS05550	COG1114	Component of the transport system for branched-chain amino acids
A6J31_RS05555	COG1482	cell wall glycoprotein biosynthetic process
A6J31_RS05565	COG2323	membrane
A6J31_RS05570	COG3237	CsbD-like
A6J31_RS05585	COG0531	amino acid
A6J31_RS05595	COG1126	abc transporter atp-binding protein
A6J31_RS05600	COG0765	amino acid transport
A6J31_RS05605	COG0765	amino acid transport
A6J31_RS05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS05615	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A6J31_RS05620	COG0386	Belongs to the glutathione peroxidase family
A6J31_RS05645	COG4989	oxidoreductase activity
A6J31_RS05650	COG1668	transmembrane transport
A6J31_RS05655	COG4152	abc transporter atp-binding protein
A6J31_RS05665	COG1476	TRANSCRIPTIONal
A6J31_RS05680	COG2514	catechol 2,3-dioxygenase activity
A6J31_RS05685	COG1959	2 iron, 2 sulfur cluster binding
A6J31_RS05695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A6J31_RS05700	COG0778	Nitroreductase
A6J31_RS05710	COG0656	L-ascorbic acid biosynthetic process
A6J31_RS05720	COG3250	beta-galactosidase activity
A6J31_RS05725	COG2211	Major facilitator Superfamily
A6J31_RS05725	COG2190	(PTS) system
A6J31_RS05730	COG2017	converts alpha-aldose to the beta-anomer
A6J31_RS05735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6J31_RS05750	COG1609	Transcriptional regulator
A6J31_RS05755	COG0366	Alpha amylase catalytic
A6J31_RS05760	COG5002	protein histidine kinase activity
A6J31_RS05765	COG0745	RESPONSE REGULATOR receiver
A6J31_RS05770	COG0577	efflux transmembrane transporter activity
A6J31_RS05775	COG1136	(ABC) transporter
A6J31_RS05805	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
A6J31_RS05810	COG1461	Dihydroxyacetone kinase
A6J31_RS05815	COG2376	Dihydroxyacetone kinase
A6J31_RS05825	COG4268	DNA restriction-modification system
A6J31_RS05830	COG1401	restriction endodeoxyribonuclease activity
A6J31_RS05835	COG3590	peptidase
A6J31_RS05855	COG0640	Transcriptional regulator
A6J31_RS05870	COG0366	Alpha amylase catalytic
A6J31_RS05870	COG5263	repeat protein
A6J31_RS05885	COG5263	repeat protein
A6J31_RS05885	COG0366	Alpha amylase catalytic
A6J31_RS05890	COG0366	Alpha amylase catalytic
A6J31_RS05890	COG5263	repeat protein
A6J31_RS05905	COG0366	Alpha amylase catalytic
A6J31_RS05905	COG5263	repeat protein
A6J31_RS05905	COG0366	Alpha amylase catalytic
A6J31_RS05905	COG5263	repeat protein
A6J31_RS05920	COG0366	Alpha amylase catalytic
A6J31_RS05920	COG5263	repeat protein
A6J31_RS05975	COG0679	Auxin Efflux Carrier
A6J31_RS05980	COG0281	malic enzyme
A6J31_RS05990	COG0583	DNA-binding transcription factor activity
A6J31_RS06000	COG0477	Major facilitator Superfamily
A6J31_RS06010	COG0110	maltose O-acetyltransferase activity
A6J31_RS06015	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A6J31_RS06025	COG5263	repeat protein
A6J31_RS06025	COG0366	Alpha amylase catalytic
A6J31_RS06075	COG0438	transferase activity, transferring glycosyl groups
A6J31_RS06085	COG0653	protein targeting
A6J31_RS06110	COG1216	Glycosyl transferase, family 2
A6J31_RS06110	COG1442	glycosyl transferase family 8
A6J31_RS06115	COG0419	ATPase involved in DNA repair
A6J31_RS06120	COG0420	3'-5' exonuclease activity
A6J31_RS06130	COG3064	Membrane
A6J31_RS06150	COG0488	(ABC) transporter
A6J31_RS06155	COG1132	(ABC) transporter
A6J31_RS06160	COG1132	(ABC) transporter
A6J31_RS06185	COG0058	SHG alpha-glucan phosphorylase activity
A6J31_RS06190	COG0297	glycogen (starch) synthase activity
A6J31_RS06200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A6J31_RS06205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A6J31_RS06210	COG1523	belongs to the glycosyl hydrolase 13 family
A6J31_RS06245	COG2197	response regulator
A6J31_RS06250	COG4585	Histidine kinase
A6J31_RS06260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A6J31_RS06265	COG0515	serine threonine protein kinase
A6J31_RS06265	COG2815	serine threonine protein kinase
A6J31_RS06275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6J31_RS06275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6J31_RS06285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A6J31_RS06300	COG0552	protein localization to endoplasmic reticulum
A6J31_RS06305	COG0561	phosphatase activity
A6J31_RS06310	COG0561	phosphatase activity
A6J31_RS06315	COG1725	Transcriptional regulator
A6J31_RS06320	COG1131	(ABC) transporter
A6J31_RS06330	COG4608	Belongs to the ABC transporter superfamily
A6J31_RS06335	COG0444	Belongs to the ABC transporter superfamily
A6J31_RS06340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J31_RS06345	COG0601	transmembrane transport
A6J31_RS06350	COG4166	transmembrane transport
A6J31_RS06355	COG4166	transmembrane transport
A6J31_RS06360	COG0280	phosphate acetyltransferase
A6J31_RS06365	COG0564	pseudouridine synthase activity
A6J31_RS06375	COG2357	RelA SpoT domain protein
A6J31_RS06390	COG1104	cysteine desulfurase activity
A6J31_RS06405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A6J31_RS06430	COG0463	Glycosyl transferase, family 2
A6J31_RS06450	COG1442	glycosyl transferase family 8
A6J31_RS06450	COG1216	Glycosyl transferase, family 2
A6J31_RS06470	COG0463	Glycosyl transferase, family 2
A6J31_RS06475	COG1216	Glycosyl transferase, family 2
A6J31_RS06480	COG1216	Glycosyl transferase, family 2
A6J31_RS06490	COG1091	dTDP-4-dehydrorhamnose reductase activity
A6J31_RS06500	COG0463	Glycosyl transferase, family 2
A6J31_RS06505	COG2151	metal-sulfur cluster biosynthetic enzyme
A6J31_RS06515	COG1970	mechanosensitive ion channel activity
A6J31_RS06520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A6J31_RS06525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS06530	COG0436	Aminotransferase
A6J31_RS06535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS06540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS06565	COG0765	amino acid transport
A6J31_RS06590	COG1187	pseudouridine synthase activity
A6J31_RS06625	COG0560	Phosphoserine phosphatase
A6J31_RS06635	COG0187	DNA topoisomerase II activity
A6J31_RS06645	COG1346	cytolysis
A6J31_RS06650	COG1380	Effector of murein hydrolase LrgA
A6J31_RS06660	COG1393	Belongs to the ArsC family
A6J31_RS06665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6J31_RS06670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A6J31_RS06685	COG1940	carbohydrate kinase activity
A6J31_RS06690	COG0346	lactoylglutathione lyase activity
A6J31_RS06705	COG1177	transmembrane transport
A6J31_RS06710	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6J31_RS06755	COG0531	amino acid
A6J31_RS06760	COG0285	dihydrofolate synthase activity
A6J31_RS06795	COG0500	methyltransferase
A6J31_RS06795	COG3615	Tellurite resistance protein tehB
A6J31_RS06815	COG0708	Exodeoxyribonuclease III
A6J31_RS06840	COG1597	lipid kinase activity
A6J31_RS06850	COG4708	membrane
A6J31_RS06860	COG0024	Methionine aminopeptidase
A6J31_RS06865	COG4109	DRTGG domain
A6J31_RS06870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J31_RS06875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A6J31_RS06880	COG0658	competence protein
A6J31_RS06880	COG2333	competence protein COMEC
A6J31_RS06885	COG1555	photosystem II stabilization
A6J31_RS06885	COG1596	polysaccharide export
A6J31_RS06890	COG0204	Acyl-transferase
A6J31_RS06895	COG0726	polysaccharide deacetylase
A6J31_RS06900	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A6J31_RS06910	COG0513	Belongs to the DEAD box helicase family
A6J31_RS06945	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A6J31_RS06965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS06970	COG1126	abc transporter atp-binding protein
A6J31_RS06975	COG0765	amino acid transport
A6J31_RS06980	COG0765	amino acid transport
A6J31_RS06985	COG1181	Belongs to the D-alanine--D-alanine ligase family
A6J31_RS06995	COG2217	Heavy metal translocating P-type atpase
A6J31_RS07020	COG0159	tryptophan synthase activity
A6J31_RS07025	COG0133	tryptophan synthase activity
A6J31_RS07030	COG0135	phosphoribosylanthranilate isomerase activity
A6J31_RS07045	COG0512	Glutamine amidotransferase of anthranilate synthase
A6J31_RS07050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A6J31_RS07055	COG1605	Chorismate mutase
A6J31_RS07055	COG0287	Prephenate dehydrogenase
A6J31_RS07065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A6J31_RS07090	COG4591	ABC-type transport system involved in lipoprotein release permease component
A6J31_RS07090	COG1136	(ABC) transporter
A6J31_RS07100	COG0789	Transcriptional regulator
A6J31_RS07105	COG2176	DNA-directed DNA polymerase activity
A6J31_RS07115	COG2151	metal-sulfur cluster biosynthetic enzyme
A6J31_RS07125	COG2081	HI0933 family
A6J31_RS07150	COG1131	(ABC) transporter
A6J31_RS07155	COG0537	adenosine 5'-monophosphoramidase activity
A6J31_RS07205	COG2226	methyltransferase
A6J31_RS07210	COG0799	negative regulation of ribosome biogenesis
A6J31_RS07215	COG1335	isochorismatase
A6J31_RS07220	COG1713	HD superfamily hydrolase involved in NAD metabolism
A6J31_RS07225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A6J31_RS07230	COG1534	Rna-binding protein
A6J31_RS07235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A6J31_RS07240	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A6J31_RS07250	COG1063	alcohol dehydrogenase
A6J31_RS07285	COG1442	glycosyl transferase family 8
A6J31_RS07285	COG1216	Glycosyl transferase, family 2
A6J31_RS07290	COG1442	glycosyl transferase family 8
A6J31_RS07295	COG2723	6-phospho-beta-galactosidase activity
A6J31_RS07300	COG1335	isochorismatase
A6J31_RS07310	COG0436	Aminotransferase
A6J31_RS07315	COG0589	response to stress
A6J31_RS07325	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A6J31_RS07335	COG1253	flavin adenine dinucleotide binding
A6J31_RS07340	COG1119	ATPase activity
A6J31_RS07355	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A6J31_RS07360	COG1242	4 iron, 4 sulfur cluster binding
A6J31_RS07365	COG3480	Lon protease (S16) C-terminal proteolytic domain
A6J31_RS07370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A6J31_RS07375	COG0742	ribosomal rna small subunit methyltransferase
A6J31_RS07390	COG1126	abc transporter atp-binding protein
A6J31_RS07395	COG0765	amino acid transport
A6J31_RS07400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS07415	COG1882	Formate acetyltransferase
A6J31_RS07440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A6J31_RS07460	COG2936	dipeptidyl-peptidase activity
A6J31_RS07490	COG1132	(ABC) transporter
A6J31_RS07495	COG1132	(ABC) transporter
A6J31_RS07515	COG4470	Protein conserved in bacteria
A6J31_RS07520	COG0737	Belongs to the 5'-nucleotidase family
A6J31_RS07535	COG0513	Belongs to the DEAD box helicase family
A6J31_RS07545	COG0768	penicillin binding
A6J31_RS07580	COG3152	Membrane
A6J31_RS07585	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A6J31_RS07590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A6J31_RS07600	COG4152	abc transporter atp-binding protein
A6J31_RS07605	COG1811	Na channel or pump
A6J31_RS07645	COG1116	anion transmembrane transporter activity
A6J31_RS07655	COG0443	Heat shock 70 kDa protein
A6J31_RS07680	COG0561	phosphatase activity
A6J31_RS07685	COG0252	asparaginase activity
A6J31_RS07690	COG3655	Transcriptional regulator
A6J31_RS07710	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A6J31_RS07725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A6J31_RS07730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A6J31_RS07735	COG0653	protein targeting
A6J31_RS07745	COG1482	cell wall glycoprotein biosynthetic process
A6J31_RS07750	COG1940	carbohydrate kinase activity
A6J31_RS07755	COG1263	PTS System
A6J31_RS07755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J31_RS07755	COG2190	(PTS) system
A6J31_RS07765	COG1609	Transcriptional regulator
A6J31_RS07780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A6J31_RS07785	COG2131	deaminase
A6J31_RS07790	COG0006	proline dipeptidase activity
A6J31_RS07880	COG3843	relaxase mobilization nuclease domain protein
A6J31_RS07900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A6J31_RS07900	COG0551	DNA topoisomerase type I activity
A6J31_RS07915	COG2003	Belongs to the UPF0758 family
A6J31_RS08015	COG1194	a g-specific adenine glycosylase
A6J31_RS08025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J31_RS08025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J31_RS08050	COG0681	Belongs to the peptidase S26 family
A6J31_RS08055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A6J31_RS08065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A6J31_RS08075	COG0456	acetyltransferase
A6J31_RS08080	COG1214	PFAM Peptidase M22, glycoprotease
A6J31_RS08095	COG3942	CHAP domain
A6J31_RS08100	COG0174	glutamine synthetase
A6J31_RS08105	COG0789	Transcriptional regulator
A6J31_RS08115	COG0126	phosphoglycerate kinase activity
A6J31_RS08145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A6J31_RS08190	COG0084	hydrolase, TatD family'
A6J31_RS08195	COG1832	CoA-binding protein
A6J31_RS08200	COG3118	belongs to the thioredoxin family
A6J31_RS08320	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6J31_RS08335	COG0706	membrane insertase activity
A6J31_RS08385	COG4166	transmembrane transport
A6J31_RS08430	COG0756	dUTP diphosphatase activity
A6J31_RS08440	COG3976	FMN-binding domain protein
A6J31_RS08440	COG1053	succinate dehydrogenase
A6J31_RS08440	COG0431	NADPH-dependent FMN reductase
A6J31_RS08460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A6J31_RS08465	COG0457	Tetratricopeptide repeat
A6J31_RS08465	COG0705	Rhomboid family
A6J31_RS08470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A6J31_RS08495	COG2226	methyltransferase
A6J31_RS08535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J31_RS08545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6J31_RS08555	COG1363	Peptidase, m42
A6J31_RS08560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A6J31_RS08565	COG1266	CAAX protease self-immunity
A6J31_RS08620	COG1459	type II secretion system
A6J31_RS08625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A6J31_RS08660	COG0440	acetolactate synthase activity
A6J31_RS08665	COG0028	Belongs to the TPP enzyme family
A6J31_RS08670	COG0129	dihydroxy-acid dehydratase activity
A6J31_RS08675	COG1461	Dihydroxyacetone kinase
A6J31_RS08685	COG0534	Mate efflux family protein
A6J31_RS08705	COG1454	alcohol dehydrogenase
A6J31_RS08705	COG1012	belongs to the aldehyde dehydrogenase family
A6J31_RS08710	COG3590	peptidase
A6J31_RS08715	COG0366	Alpha amylase catalytic
A6J31_RS08720	COG1263	PTS System
A6J31_RS08720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J31_RS08725	COG2188	Transcriptional regulator
A6J31_RS08730	COG4475	Protein of unknown function (DUF436)
A6J31_RS08790	COG0563	adenylate kinase activity
A6J31_RS08795	COG0201	protein transport
A6J31_RS08830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A6J31_RS08900	COG0051	transcription antitermination factor activity, RNA binding
A6J31_RS08920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A6J31_RS08935	COG2855	membrane
A6J31_RS08970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A6J31_RS08975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A6J31_RS09010	COG0602	queuosine metabolic process
A6J31_RS09020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J31_RS09055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J31_RS09055	COG1263	PTS System
A6J31_RS09060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A6J31_RS09070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A6J31_RS09120	COG4974	Belongs to the 'phage' integrase family
A6J31_RS09125	COG2815	serine threonine protein kinase
A6J31_RS09125	COG0515	serine threonine protein kinase
A6J31_RS09135	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A6J31_RS09140	COG1105	Belongs to the carbohydrate kinase PfkB family
A6J31_RS09145	COG5001	Diguanylate cyclase
A6J31_RS09145	COG3300	MHYT domain
A6J31_RS09185	COG0494	nUDIX hydrolase
A6J31_RS09190	COG1695	Transcriptional regulator
A6J31_RS09205	COG1511	domain protein
A6J31_RS09205	COG1511	domain protein
A6J31_RS09215	COG3759	membrane
A6J31_RS09235	COG0305	Participates in initiation and elongation during chromosome replication
A6J31_RS09255	COG2095	MarC family integral membrane protein
A6J31_RS09270	COG0741	lytic transglycosylase activity
A6J31_RS09275	COG1388	LysM domain
A6J31_RS09275	COG3584	3D domain protein
A6J31_RS09280	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A6J31_RS09295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A6J31_RS09305	COG0612	Peptidase, M16
A6J31_RS09310	COG0612	Peptidase, M16
A6J31_RS09335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J31_RS09340	COG0488	(ABC) transporter
A6J31_RS09375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6J31_RS09380	COG1475	DNA binding
A6J31_RS09395	COG0592	DNA-directed DNA polymerase activity
A6J31_RS09405	COG0012	GTP binding
A6J31_RS09415	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A6J31_RS09420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A6J31_RS09450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A6J31_RS09580	COG0436	Aminotransferase
A6J31_RS09595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6J31_RS09605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A6J31_RS09615	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A6J31_RS09620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A6J31_RS09635	COG0151	Belongs to the GarS family
A6J31_RS09640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A6J31_RS09655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A6J31_RS09670	COG4550	Control of competence regulator ComK, YlbF/YmcA
A6J31_RS09710	COG2818	Glycosylase
A6J31_RS09715	COG1546	Belongs to the CinA family
A6J31_RS09715	COG1058	Belongs to the CinA family
A6J31_RS09725	COG1393	Belongs to the ArsC family
A6J31_RS09810	COG2176	DNA-directed DNA polymerase activity
A6J31_RS09815	COG2309	aminopeptidase activity
A6J31_RS09825	COG1846	Transcriptional regulator
A6J31_RS09840	COG3634	alkyl hydroperoxide reductase activity
A6J31_RS09845	COG0450	alkyl hydroperoxide reductase
A6J31_RS09865	COG4463	regulation of RNA biosynthetic process
A6J31_RS09870	COG0542	response to heat
A6J31_RS09875	COG1686	Belongs to the peptidase S11 family
A6J31_RS09880	COG1686	Belongs to the peptidase S11 family
A6J31_RS09895	COG1045	serine acetyltransferase
A6J31_RS09905	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A6J31_RS09920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J31_RS09925	COG3688	RNA-binding protein containing a PIN domain
A6J31_RS09940	COG1476	TRANSCRIPTIONal
A6J31_RS09945	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A6J31_RS09985	COG0477	Major facilitator Superfamily
A6J31_RS10015	COG4509	Sortase family
A6J31_RS10025	COG3830	Belongs to the UPF0237 family
A6J31_RS10035	COG0588	phosphoglycerate mutase activity
A6J31_RS10040	COG1876	peptidase activity
A6J31_RS10055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A6J31_RS10075	COG0351	phosphomethylpyrimidine kinase
A6J31_RS10115	COG0668	transmembrane transport
A6J31_RS10140	COG0494	nUDIX hydrolase
A6J31_RS10150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A6J31_RS10155	COG0737	Belongs to the 5'-nucleotidase family
A6J31_RS10180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A6J31_RS10220	COG1126	abc transporter atp-binding protein
A6J31_RS10225	COG0765	amino acid transport
A6J31_RS10245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A6J31_RS10255	COG0719	Fe-S assembly protein
A6J31_RS10260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A6J31_RS10285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6J31_RS10295	COG1121	(ABC) transporter
A6J31_RS10300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6J31_RS10325	COG1396	sequence-specific DNA binding
A6J31_RS10330	COG1132	(ABC) transporter
A6J31_RS10350	COG4589	Belongs to the CDS family
A6J31_RS10365	COG4120	Belongs to the binding-protein-dependent transport system permease family
A6J31_RS10370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6J31_RS10370	COG1116	anion transmembrane transporter activity
A6J31_RS10400	COG0564	pseudouridine synthase activity
A6J31_RS10405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J31_RS10430	COG0561	phosphatase activity
A6J31_RS10435	COG1349	DNA-binding transcription factor activity
A6J31_RS10470	COG1733	regulation of RNA biosynthetic process
A6J31_RS10485	COG3279	Response regulator of the LytR AlgR family
A6J31_RS10495	COG0789	Transcriptional regulator
A6J31_RS10500	COG1136	(ABC) transporter
A6J31_RS10500	COG0577	efflux transmembrane transporter activity
A6J31_RS10505	COG1136	(ABC) transporter
A6J31_RS10505	COG0577	efflux transmembrane transporter activity
A6J31_RS10510	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A6J31_RS10525	COG3579	cysteine-type endopeptidase activity
A6J31_RS10530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J31_RS10555	COG0116	Belongs to the methyltransferase superfamily
A6J31_RS10565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A6J31_RS10585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A6J31_RS10600	COG1254	Belongs to the acylphosphatase family
A6J31_RS10605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J31_RS10630	COG1309	transcriptional regulator
A6J31_RS10645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A6J31_RS10665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A6J31_RS10670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A6J31_RS10675	COG1187	pseudouridine synthase activity
A6J31_RS10690	COG0569	domain protein
A6J31_RS10700	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A6J31_RS10705	COG0671	phosphoesterase, PA-phosphatase related
A6J31_RS10715	COG2274	protein secretion by the type I secretion system
A6J31_RS10745	COG0804	urea catabolic process
A6J31_RS10755	COG0830	nickel cation binding
A6J31_RS10765	COG0829	nickel cation binding
A6J31_RS10770	COG0310	cobalt ion transport
A6J31_RS10775	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A6J31_RS10780	COG1122	ATPase activity
A6J31_RS10785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS10790	COG1464	Belongs to the NlpA lipoprotein family
A6J31_RS10800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A6J31_RS10810	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
A6J31_RS10825	COG1122	ATPase activity
A6J31_RS10840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J31_RS10855	COG0745	RESPONSE REGULATOR receiver
A6J31_RS10860	COG5002	protein histidine kinase activity
A6J31_RS10875	COG1484	DNA-dependent DNA replication
A6J31_RS10900	COG3716	PTS system mannose fructose sorbose family IID component
A6J31_RS10905	COG3715	PTS system
A6J31_RS10920	COG3716	PTS system mannose fructose sorbose family IID component
A6J31_RS10925	COG3715	PTS system
A6J31_RS10935	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A6J31_RS10940	COG0561	phosphatase activity
A6J31_RS10945	COG2252	PERMEase
A6J31_RS10950	COG0802	atpase or kinase
A6J31_RS10955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J31_RS10960	COG1316	TRANSCRIPTIONal
A6J31_RS10970	COG0195	Participates in both transcription termination and antitermination
A6J31_RS10975	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A6J31_RS10985	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A6J31_RS11010	COG2244	polysaccharide biosynthetic process
A6J31_RS11015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A6J31_RS11020	COG0626	cystathionine gamma-synthase activity
A6J31_RS11025	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A6J31_RS11060	COG4471	UPF0298 protein
A6J31_RS11085	COG0410	ABC transporter
A6J31_RS11090	COG0517	IMP dehydrogenase activity
A6J31_RS11100	COG1739	Uncharacterized protein family UPF0029
A6J31_RS11105	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A6J31_RS11200	COG0527	aspartate kinase activity
A6J31_RS11205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6J31_RS11210	COG1024	Enoyl-CoA hydratase
A6J31_RS11215	COG1846	Transcriptional regulator
A6J31_RS11235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A6J31_RS11240	COG1028	Short-chain dehydrogenase reductase Sdr
A6J31_RS11245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6J31_RS11260	COG0439	Biotin carboxylase
A6J31_RS11285	COG1349	DNA-binding transcription factor activity
A6J31_RS11290	COG1105	Belongs to the carbohydrate kinase PfkB family
A6J31_RS11295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J31_RS11295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J31_RS11295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J31_RS11300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J31_RS11305	COG0285	dihydrofolate synthase activity
A6J31_RS11315	COG1104	cysteine desulfurase activity
A6J31_RS11320	COG0301	tRNA thio-modification