locus-tag	class	description
A6J31_RS00065	COG1136	(ABC) transporter
A6J31_RS00070	COG0577	efflux transmembrane transporter activity
A6J31_RS00090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A6J31_RS00105	COG4974	Belongs to the 'phage' integrase family
A6J31_RS00140	COG1396	sequence-specific DNA binding
A6J31_RS00145	COG2226	methyltransferase
A6J31_RS00250	COG4974	Belongs to the 'phage' integrase family
A6J31_RS00370	COG3290	protein histidine kinase activity
A6J31_RS00375	COG3279	Response regulator of the LytR AlgR family
A6J31_RS00390	COG2274	protein secretion by the type I secretion system
A6J31_RS00515	COG2205	protein histidine kinase activity
A6J31_RS00520	COG0745	RESPONSE REGULATOR receiver
A6J31_RS00555	COG0494	nUDIX hydrolase
A6J31_RS00565	COG1373	ATPase (AAA superfamily
A6J31_RS00575	COG3655	Transcriptional regulator
A6J31_RS00600	COG1132	(ABC) transporter
A6J31_RS00635	COG1136	(ABC) transporter
A6J31_RS00650	COG2197	response regulator
A6J31_RS00695	COG3279	Response regulator of the LytR AlgR family
A6J31_RS00740	COG1136	(ABC) transporter
A6J31_RS00740	COG0577	efflux transmembrane transporter activity
A6J31_RS00755	COG1247	-acetyltransferase
A6J31_RS00775	COG0542	response to heat
A6J31_RS00800	COG1280	lysine exporter protein (LysE YggA)
A6J31_RS00840	COG2184	nucleotidyltransferase activity
A6J31_RS00875	COG1131	(ABC) transporter
A6J31_RS00950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A6J31_RS00955	COG1121	(ABC) transporter
A6J31_RS00990	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A6J31_RS01120	COG0488	(ABC) transporter
A6J31_RS01140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A6J31_RS01150	COG0242	peptide deformylase activity
A6J31_RS01175	COG2357	RelA SpoT domain protein
A6J31_RS01180	COG0745	RESPONSE REGULATOR receiver
A6J31_RS01215	COG1702	phosphate starvation-inducible protein PhoH
A6J31_RS01235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J31_RS01235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J31_RS01240	COG0656	L-ascorbic acid biosynthetic process
A6J31_RS01245	COG0583	DNA-binding transcription factor activity
A6J31_RS01270	COG2223	nitrite transmembrane transporter activity
A6J31_RS01275	COG4122	O-methyltransferase activity
A6J31_RS01280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6J31_RS01330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A6J31_RS01335	COG0436	Aminotransferase
A6J31_RS01345	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A6J31_RS01350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A6J31_RS01355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A6J31_RS01360	COG0726	polysaccharide deacetylase
A6J31_RS01375	COG2962	Rard protein
A6J31_RS01410	COG0519	Catalyzes the synthesis of GMP from XMP
A6J31_RS01435	COG0356	it plays a direct role in the translocation of protons across the membrane
A6J31_RS01470	COG0772	Belongs to the SEDS family
A6J31_RS01480	COG0149	triose-phosphate isomerase activity
A6J31_RS01500	COG0470	DNA polymerase III
A6J31_RS01505	COG1774	PSP1 C-terminal conserved region
A6J31_RS01510	COG4467	Involved in initiation control of chromosome replication
A6J31_RS01520	COG0004	ammonium transporteR
A6J31_RS01525	COG0347	Belongs to the P(II) protein family
A6J31_RS01530	COG1388	LysM domain
A6J31_RS01530	COG1705	Flagellar rod assembly protein muramidase FlgJ
A6J31_RS01550	COG1283	sodium-dependent phosphate transmembrane transporter activity
A6J31_RS01580	COG1113	amino acid transport
A6J31_RS01590	COG1263	PTS System
A6J31_RS01590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J31_RS01590	COG2190	(PTS) system
A6J31_RS01640	COG0564	pseudouridine synthase activity
A6J31_RS01660	COG0505	Belongs to the CarA family
A6J31_RS01680	COG1136	(ABC) transporter
A6J31_RS01685	COG0577	efflux transmembrane transporter activity
A6J31_RS01705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A6J31_RS01710	COG0583	DNA-binding transcription factor activity
A6J31_RS01720	COG1132	(ABC) transporter
A6J31_RS01740	COG3279	Response regulator of the LytR AlgR family
A6J31_RS01745	COG1131	(ABC) transporter
A6J31_RS01780	COG1187	pseudouridine synthase activity
A6J31_RS01785	COG1473	amidohydrolase
A6J31_RS01790	COG0686	Belongs to the AlaDH PNT family
A6J31_RS01800	COG2267	carboxylic ester hydrolase activity
A6J31_RS01815	COG5002	protein histidine kinase activity
A6J31_RS01815	COG3850	Histidine kinase
A6J31_RS01820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J31_RS01855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A6J31_RS01890	COG0438	transferase activity, transferring glycosyl groups
A6J31_RS01905	COG0596	Alpha beta hydrolase
A6J31_RS01920	COG1272	protein, Hemolysin III
A6J31_RS01935	COG3425	synthase
A6J31_RS01945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A6J31_RS01965	COG0833	amino acid
A6J31_RS01970	COG2040	homocysteine
A6J31_RS01990	COG0187	DNA topoisomerase II activity
A6J31_RS02010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6J31_RS02030	COG0539	negative regulation of cytoplasmic translation
A6J31_RS02070	COG0494	nUDIX hydrolase
A6J31_RS02075	COG0542	response to heat
A6J31_RS02080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A6J31_RS02085	COG4703	Protein of unknown function (DUF1797)
A6J31_RS02090	COG0765	amino acid transport
A6J31_RS02095	COG1126	abc transporter atp-binding protein
A6J31_RS02125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A6J31_RS02130	COG0768	penicillin binding
A6J31_RS02135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A6J31_RS02150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A6J31_RS02155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A6J31_RS02160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A6J31_RS02165	COG0237	dephospho-CoA kinase activity
A6J31_RS02170	COG2814	Major facilitator Superfamily
A6J31_RS02185	COG0557	exoribonuclease II activity
A6J31_RS02200	COG1185	polyribonucleotide nucleotidyltransferase activity
A6J31_RS02205	COG0006	proline dipeptidase activity
A6J31_RS02210	COG1609	Transcriptional regulator
A6J31_RS02240	COG1368	sulfuric ester hydrolase activity
A6J31_RS02245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A6J31_RS02270	COG0287	Prephenate dehydrogenase
A6J31_RS02285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A6J31_RS02295	COG0077	Prephenate dehydratase
A6J31_RS02325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A6J31_RS02330	COG2226	methyltransferase
A6J31_RS02345	COG1131	(ABC) transporter
A6J31_RS02370	COG0135	phosphoribosylanthranilate isomerase activity
A6J31_RS02400	COG0488	(ABC) transporter
A6J31_RS02460	COG1131	(ABC) transporter
A6J31_RS02465	COG1132	(ABC) transporter
A6J31_RS02490	COG0640	Transcriptional regulator
A6J31_RS02495	COG2217	Heavy metal translocating P-type atpase
A6J31_RS02510	COG2807	transmembrane transport
A6J31_RS02515	COG1307	EDD domain protein, DegV family
A6J31_RS02525	COG3142	Participates in the control of copper homeostasis
A6J31_RS02540	COG0477	Major facilitator Superfamily
A6J31_RS02565	COG1120	ATPase activity
A6J31_RS02575	COG2819	hydrolase of the alpha beta superfamily
A6J31_RS02580	COG1597	lipid kinase activity
A6J31_RS02590	COG2261	transglycosylase associated protein
A6J31_RS02595	COG3237	CsbD-like
A6J31_RS02600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J31_RS02605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A6J31_RS02610	COG0022	dehydrogenase e1 component
A6J31_RS02615	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J31_RS02620	COG2226	methyltransferase
A6J31_RS02685	COG0659	secondary active sulfate transmembrane transporter activity
A6J31_RS02690	COG3689	TIGRFAM TIGR03943 family protein
A6J31_RS02695	COG0701	Predicted permease
A6J31_RS02700	COG2183	response to ionizing radiation
A6J31_RS02720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A6J31_RS02745	COG0826	peptidase U32
A6J31_RS02755	COG1268	BioY protein
A6J31_RS02765	COG4443	Transcriptional Coactivator p15 (PC4)
A6J31_RS02770	COG1914	H( )-stimulated, divalent metal cation uptake system
A6J31_RS02780	COG0494	nUDIX hydrolase
A6J31_RS02800	COG1705	Flagellar rod assembly protein muramidase FlgJ
A6J31_RS02800	COG1388	LysM domain
A6J31_RS02820	COG0588	phosphoglycerate mutase activity
A6J31_RS02825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A6J31_RS02840	COG0561	phosphatase activity
A6J31_RS02855	COG4221	oxidoreductase activity
A6J31_RS02885	COG1704	LemA family
A6J31_RS02890	COG0501	Belongs to the peptidase M48B family
A6J31_RS02925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A6J31_RS02935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A6J31_RS02950	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A6J31_RS02955	COG0783	Belongs to the Dps family
A6J31_RS02960	COG0735	belongs to the Fur family
A6J31_RS02965	COG4483	Protein conserved in bacteria
A6J31_RS02970	COG1940	carbohydrate kinase activity
A6J31_RS02975	COG1217	gtp-binding protein TYPA
A6J31_RS03000	COG0849	cell division
A6J31_RS03010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A6J31_RS03020	COG0762	integral membrane protein
A6J31_RS03030	COG3599	regulation of cell shape
A6J31_RS03040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6J31_RS03045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6J31_RS03050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A6J31_RS03055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A6J31_RS03060	COG0372	Belongs to the citrate synthase family
A6J31_RS03100	COG0513	Belongs to the DEAD box helicase family
A6J31_RS03110	COG0488	(ABC) transporter
A6J31_RS03125	COG0392	lysyltransferase activity
A6J31_RS03125	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A6J31_RS03130	COG3442	glutamine amidotransferase
A6J31_RS03135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A6J31_RS03160	COG2384	SAM-dependent methyltransferase
A6J31_RS03175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J31_RS03185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A6J31_RS03195	COG1088	dTDP-glucose 4,6-dehydratase activity
A6J31_RS03210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6J31_RS03220	COG0647	UMP catabolic process
A6J31_RS03260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A6J31_RS03270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A6J31_RS03280	COG0107	imidazoleglycerol-phosphate synthase activity
A6J31_RS03320	COG0366	Alpha amylase catalytic
A6J31_RS03320	COG5263	repeat protein
A6J31_RS03325	COG0366	Alpha amylase catalytic
A6J31_RS03325	COG5263	repeat protein
A6J31_RS03340	COG0519	Catalyzes the synthesis of GMP from XMP
A6J31_RS03360	COG0366	Alpha amylase catalytic
A6J31_RS03360	COG5263	repeat protein
A6J31_RS03365	COG0772	Belongs to the SEDS family
A6J31_RS03370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A6J31_RS03385	COG0300	oxidoreductase activity
A6J31_RS03390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A6J31_RS03390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A6J31_RS03410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A6J31_RS03435	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A6J31_RS03440	COG1438	arginine binding
A6J31_RS03445	COG0497	DNA recombination
A6J31_RS03455	COG2755	lipolytic protein G-D-S-L family
A6J31_RS03465	COG0776	regulation of translation
A6J31_RS03475	COG0167	dihydroorotate dehydrogenase activity
A6J31_RS03480	COG0588	phosphoglycerate mutase activity
A6J31_RS03500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A6J31_RS03505	COG0066	3-isopropylmalate dehydratase activity
A6J31_RS03520	COG0469	pyruvate kinase activity
A6J31_RS03545	COG3842	ATPase activity
A6J31_RS03570	COG0716	FMN binding
A6J31_RS03585	COG0038	chloride channel
A6J31_RS03590	COG0335	large ribosomal subunit rRNA binding
A6J31_RS03610	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A6J31_RS03615	COG1956	GAF domain-containing protein
A6J31_RS03620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A6J31_RS03630	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A6J31_RS03630	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A6J31_RS03635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A6J31_RS03685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6J31_RS03710	COG0765	amino acid transport
A6J31_RS03715	COG0765	amino acid transport
A6J31_RS03720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS03725	COG1126	abc transporter atp-binding protein
A6J31_RS03730	COG0765	amino acid transport
A6J31_RS03735	COG0765	amino acid transport
A6J31_RS03740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS03745	COG1126	abc transporter atp-binding protein
A6J31_RS03750	COG0745	RESPONSE REGULATOR receiver
A6J31_RS03755	COG5002	protein histidine kinase activity
A6J31_RS03760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A6J31_RS03765	COG2832	Protein of unknown function (DUF454)
A6J31_RS03770	COG2348	transferase activity, transferring amino-acyl groups
A6J31_RS03795	COG0778	Nitroreductase
A6J31_RS03805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A6J31_RS03815	COG2884	Cell division ATP-binding protein ftsE
A6J31_RS03820	COG2177	Part of the ABC transporter FtsEX involved in
A6J31_RS03825	COG1051	belongs to the nudix hydrolase family
A6J31_RS03830	COG0628	permease
A6J31_RS03845	COG1705	Flagellar rod assembly protein muramidase FlgJ
A6J31_RS03875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A6J31_RS03880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A6J31_RS03910	COG1573	uracil-dna glycosylase
A6J31_RS03930	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A6J31_RS03940	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A6J31_RS03960	COG0813	purine-nucleoside phosphorylase activity
A6J31_RS03965	COG1316	TRANSCRIPTIONal
A6J31_RS03995	COG0297	glycogen (starch) synthase activity
A6J31_RS04005	COG1442	glycosyl transferase family 8
A6J31_RS04005	COG1216	Glycosyl transferase, family 2
A6J31_RS04015	COG0438	transferase activity, transferring glycosyl groups
A6J31_RS04040	COG0561	phosphatase activity
A6J31_RS04055	COG0588	phosphoglycerate mutase activity
A6J31_RS04060	COG0628	permease
A6J31_RS04085	COG4667	esterase of the alpha-beta hydrolase superfamily
A6J31_RS04100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A6J31_RS04130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A6J31_RS04135	COG0022	dehydrogenase e1 component
A6J31_RS04135	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J31_RS04140	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J31_RS04155	COG0860	N-Acetylmuramoyl-L-alanine amidase
A6J31_RS04160	COG1523	belongs to the glycosyl hydrolase 13 family
A6J31_RS04165	COG2822	iron ion transport
A6J31_RS04170	COG2837	iron assimilation
A6J31_RS04175	COG0672	)-iron permease
A6J31_RS04180	COG0805	protein transport
A6J31_RS04185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A6J31_RS04195	COG3842	ATPase activity
A6J31_RS04200	COG3833	ABC-type maltose transport systems, permease component
A6J31_RS04205	COG1175	transmembrane transport
A6J31_RS04215	COG1609	Transcriptional regulator
A6J31_RS04220	COG1640	4-alpha-glucanotransferase
A6J31_RS04225	COG0058	SHG alpha-glucan phosphorylase activity
A6J31_RS04235	COG0095	Lipoate-protein ligase
A6J31_RS04250	COG0704	Plays a role in the regulation of phosphate uptake
A6J31_RS04265	COG0581	inorganic phosphate transmembrane transporter activity
A6J31_RS04270	COG0573	inorganic phosphate transmembrane transporter activity
A6J31_RS04280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6J31_RS04280	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A6J31_RS04285	COG0483	inositol monophosphate 1-phosphatase activity
A6J31_RS04295	COG1393	Belongs to the ArsC family
A6J31_RS04300	COG0196	riboflavin kinase activity
A6J31_RS04305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A6J31_RS04335	COG2873	o-acetylhomoserine
A6J31_RS04340	COG0210	DNA helicase
A6J31_RS04345	COG1115	amino acid carrier protein
A6J31_RS04355	COG1917	Cupin 2, conserved barrel domain protein
A6J31_RS04355	COG2207	Transcriptional regulator
A6J31_RS04360	COG0737	Belongs to the 5'-nucleotidase family
A6J31_RS04365	COG0765	amino acid transport
A6J31_RS04370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS04385	COG0284	orotidine-5'-phosphate decarboxylase activity
A6J31_RS04395	COG0167	dihydroorotate dehydrogenase activity
A6J31_RS04420	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A6J31_RS04430	COG0534	Mate efflux family protein
A6J31_RS04435	COG4607	ABC-type enterochelin transport system periplasmic component
A6J31_RS04510	COG1063	alcohol dehydrogenase
A6J31_RS04520	COG1230	cation diffusion facilitator family transporter
A6J31_RS04545	COG0596	Alpha beta hydrolase
A6J31_RS04550	COG3321	synthase
A6J31_RS04550	COG0604	alcohol dehydrogenase
A6J31_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
A6J31_RS04565	COG1122	ATPase activity
A6J31_RS04575	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A6J31_RS04595	COG1136	(ABC) transporter
A6J31_RS04595	COG0577	efflux transmembrane transporter activity
A6J31_RS04615	COG1174	glycine betaine transport
A6J31_RS04630	COG1846	Transcriptional regulator
A6J31_RS04650	COG3527	Alpha-acetolactate decarboxylase
A6J31_RS04655	COG0028	Belongs to the TPP enzyme family
A6J31_RS04720	COG1131	(ABC) transporter
A6J31_RS04725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A6J31_RS04730	COG0758	DNA mediated transformation
A6J31_RS04735	COG1940	carbohydrate kinase activity
A6J31_RS04745	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A6J31_RS04755	COG1827	regulation of RNA biosynthetic process
A6J31_RS04765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6J31_RS04775	COG2188	Transcriptional regulator
A6J31_RS04780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A6J31_RS04780	COG0519	Catalyzes the synthesis of GMP from XMP
A6J31_RS04790	COG1064	alcohol dehydrogenase
A6J31_RS04805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A6J31_RS04810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS04815	COG1126	abc transporter atp-binding protein
A6J31_RS04820	COG0765	amino acid transport
A6J31_RS04825	COG2824	Alkylphosphonate utilization operon protein PhnA
A6J31_RS04830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A6J31_RS04835	COG0583	DNA-binding transcription factor activity
A6J31_RS04840	COG1705	Flagellar rod assembly protein muramidase FlgJ
A6J31_RS04840	COG1388	LysM domain
A6J31_RS04860	COG0803	Belongs to the bacterial solute-binding protein 9 family
A6J31_RS04860	COG3443	Belongs to the bacterial solute-binding protein 9 family
A6J31_RS04910	COG0720	synthase
A6J31_RS04920	COG0251	oxidation-reduction process
A6J31_RS04930	COG0017	Asparaginyl-tRNA synthetase
A6J31_RS04935	COG0436	Aminotransferase
A6J31_RS04945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A6J31_RS04945	COG1199	ATP-dependent helicase activity
A6J31_RS04955	COG1079	Belongs to the binding-protein-dependent transport system permease family
A6J31_RS04960	COG4603	Belongs to the binding-protein-dependent transport system permease family
A6J31_RS04965	COG3845	ABC transporter
A6J31_RS04970	COG1744	ABC transporter substrate-binding protein PnrA-like
A6J31_RS04975	COG0295	cytidine deaminase activity
A6J31_RS04980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A6J31_RS04985	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A6J31_RS04990	COG2813	Specifically methylates the guanine in position
A6J31_RS05005	COG5002	protein histidine kinase activity
A6J31_RS05010	COG0745	RESPONSE REGULATOR receiver
A6J31_RS05025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A6J31_RS05030	COG4684	Psort location CytoplasmicMembrane, score
A6J31_RS05035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A6J31_RS05060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A6J31_RS05065	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A6J31_RS05075	COG1696	Membrane protein involved in D-alanine export
A6J31_RS05090	COG1132	(ABC) transporter
A6J31_RS05115	COG0009	L-threonylcarbamoyladenylate synthase
A6J31_RS05120	COG2890	protein-(glutamine-N5) methyltransferase activity
A6J31_RS05130	COG1435	thymidine kinase activity
A6J31_RS05135	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A6J31_RS05140	COG0625	glutathione transferase activity
A6J31_RS05145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A6J31_RS05175	COG0346	lactoylglutathione lyase activity
A6J31_RS05180	COG3764	Sortase (surface protein transpeptidase)
A6J31_RS05200	COG0488	(ABC) transporter
A6J31_RS05225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J31_RS05230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A6J31_RS05230	COG1328	CTP reductase activity
A6J31_RS05270	COG1196	nuclear chromosome segregation
A6J31_RS05285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A6J31_RS05295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J31_RS05300	COG1247	-acetyltransferase
A6J31_RS05305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J31_RS05315	COG1011	Hydrolase
A6J31_RS05320	COG1760	l-serine dehydratase
A6J31_RS05325	COG1760	l-serine dehydratase
A6J31_RS05330	COG3583	domain protein
A6J31_RS05330	COG5492	domain, Protein
A6J31_RS05330	COG1621	beta-fructofuranosidase activity
A6J31_RS05335	COG0697	spore germination
A6J31_RS05405	COG2197	response regulator
A6J31_RS05410	COG4585	Histidine kinase
A6J31_RS05420	COG1131	(ABC) transporter
A6J31_RS05435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J31_RS05445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J31_RS05450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6J31_RS05490	COG0443	Heat shock 70 kDa protein
A6J31_RS05495	COG0385	Bile acid
A6J31_RS05505	COG0842	Transport permease protein
A6J31_RS05510	COG1131	(ABC) transporter
A6J31_RS05530	COG0577	efflux transmembrane transporter activity
A6J31_RS05535	COG1136	(ABC) transporter
A6J31_RS05545	COG0745	RESPONSE REGULATOR receiver
A6J31_RS05555	COG2233	PERMEase
A6J31_RS05560	COG0534	Mate efflux family protein
A6J31_RS05570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J31_RS05570	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J31_RS05595	COG1114	Component of the transport system for branched-chain amino acids
A6J31_RS05600	COG1482	cell wall glycoprotein biosynthetic process
A6J31_RS05610	COG2323	membrane
A6J31_RS05615	COG3237	CsbD-like
A6J31_RS05630	COG0531	amino acid
A6J31_RS05640	COG1126	abc transporter atp-binding protein
A6J31_RS05645	COG0765	amino acid transport
A6J31_RS05650	COG0765	amino acid transport
A6J31_RS05655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS05660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A6J31_RS05665	COG0386	Belongs to the glutathione peroxidase family
A6J31_RS05690	COG4989	oxidoreductase activity
A6J31_RS05695	COG1668	transmembrane transport
A6J31_RS05700	COG4152	abc transporter atp-binding protein
A6J31_RS05710	COG1476	TRANSCRIPTIONal
A6J31_RS05725	COG2514	catechol 2,3-dioxygenase activity
A6J31_RS05730	COG1959	2 iron, 2 sulfur cluster binding
A6J31_RS05740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A6J31_RS05745	COG0778	Nitroreductase
A6J31_RS05755	COG0656	L-ascorbic acid biosynthetic process
A6J31_RS05765	COG3250	beta-galactosidase activity
A6J31_RS05770	COG2211	Major facilitator Superfamily
A6J31_RS05770	COG2190	(PTS) system
A6J31_RS05775	COG2017	converts alpha-aldose to the beta-anomer
A6J31_RS05780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6J31_RS05795	COG1609	Transcriptional regulator
A6J31_RS05800	COG0366	Alpha amylase catalytic
A6J31_RS05805	COG5002	protein histidine kinase activity
A6J31_RS05810	COG0745	RESPONSE REGULATOR receiver
A6J31_RS05815	COG0577	efflux transmembrane transporter activity
A6J31_RS05820	COG1136	(ABC) transporter
A6J31_RS05850	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
A6J31_RS05855	COG1461	Dihydroxyacetone kinase
A6J31_RS05860	COG2376	Dihydroxyacetone kinase
A6J31_RS05870	COG4268	DNA restriction-modification system
A6J31_RS05875	COG1401	restriction endodeoxyribonuclease activity
A6J31_RS05880	COG3590	peptidase
A6J31_RS05900	COG0640	Transcriptional regulator
A6J31_RS05915	COG5263	repeat protein
A6J31_RS05915	COG0366	Alpha amylase catalytic
A6J31_RS05930	COG5263	repeat protein
A6J31_RS05930	COG0366	Alpha amylase catalytic
A6J31_RS05935	COG0366	Alpha amylase catalytic
A6J31_RS05935	COG5263	repeat protein
A6J31_RS05950	COG0366	Alpha amylase catalytic
A6J31_RS05950	COG5263	repeat protein
A6J31_RS05950	COG0366	Alpha amylase catalytic
A6J31_RS05950	COG5263	repeat protein
A6J31_RS05965	COG5263	repeat protein
A6J31_RS05965	COG0366	Alpha amylase catalytic
A6J31_RS06020	COG0679	Auxin Efflux Carrier
A6J31_RS06025	COG0281	malic enzyme
A6J31_RS06035	COG0583	DNA-binding transcription factor activity
A6J31_RS06045	COG0477	Major facilitator Superfamily
A6J31_RS06055	COG0110	maltose O-acetyltransferase activity
A6J31_RS06060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A6J31_RS06070	COG0366	Alpha amylase catalytic
A6J31_RS06070	COG5263	repeat protein
A6J31_RS06125	COG0438	transferase activity, transferring glycosyl groups
A6J31_RS06135	COG0653	protein targeting
A6J31_RS06160	COG1216	Glycosyl transferase, family 2
A6J31_RS06160	COG1442	glycosyl transferase family 8
A6J31_RS06165	COG0419	ATPase involved in DNA repair
A6J31_RS06170	COG0420	3'-5' exonuclease activity
A6J31_RS06180	COG3064	Membrane
A6J31_RS06210	COG0488	(ABC) transporter
A6J31_RS06215	COG1132	(ABC) transporter
A6J31_RS06220	COG1132	(ABC) transporter
A6J31_RS06245	COG0058	SHG alpha-glucan phosphorylase activity
A6J31_RS06250	COG0297	glycogen (starch) synthase activity
A6J31_RS06260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A6J31_RS06265	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A6J31_RS06270	COG1523	belongs to the glycosyl hydrolase 13 family
A6J31_RS06305	COG2197	response regulator
A6J31_RS06310	COG4585	Histidine kinase
A6J31_RS06320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A6J31_RS06325	COG0515	serine threonine protein kinase
A6J31_RS06325	COG2815	serine threonine protein kinase
A6J31_RS06335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6J31_RS06335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6J31_RS06345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A6J31_RS06360	COG0552	protein localization to endoplasmic reticulum
A6J31_RS06365	COG0561	phosphatase activity
A6J31_RS06370	COG0561	phosphatase activity
A6J31_RS06375	COG1725	Transcriptional regulator
A6J31_RS06380	COG1131	(ABC) transporter
A6J31_RS06390	COG4608	Belongs to the ABC transporter superfamily
A6J31_RS06395	COG0444	Belongs to the ABC transporter superfamily
A6J31_RS06400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J31_RS06405	COG0601	transmembrane transport
A6J31_RS06410	COG4166	transmembrane transport
A6J31_RS06415	COG4166	transmembrane transport
A6J31_RS06420	COG0280	phosphate acetyltransferase
A6J31_RS06425	COG0564	pseudouridine synthase activity
A6J31_RS06435	COG2357	RelA SpoT domain protein
A6J31_RS06450	COG1104	cysteine desulfurase activity
A6J31_RS06465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A6J31_RS06490	COG0463	Glycosyl transferase, family 2
A6J31_RS06510	COG1442	glycosyl transferase family 8
A6J31_RS06510	COG1216	Glycosyl transferase, family 2
A6J31_RS06530	COG0463	Glycosyl transferase, family 2
A6J31_RS06535	COG1216	Glycosyl transferase, family 2
A6J31_RS06540	COG1216	Glycosyl transferase, family 2
A6J31_RS06550	COG1091	dTDP-4-dehydrorhamnose reductase activity
A6J31_RS06560	COG0463	Glycosyl transferase, family 2
A6J31_RS06565	COG2151	metal-sulfur cluster biosynthetic enzyme
A6J31_RS06570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A6J31_RS06575	COG0358	DNA primase activity
A6J31_RS06580	COG1970	mechanosensitive ion channel activity
A6J31_RS06585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A6J31_RS06590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS06595	COG0436	Aminotransferase
A6J31_RS06600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS06605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS06630	COG0765	amino acid transport
A6J31_RS06655	COG1187	pseudouridine synthase activity
A6J31_RS06690	COG0560	Phosphoserine phosphatase
A6J31_RS06700	COG0187	DNA topoisomerase II activity
A6J31_RS06710	COG1346	cytolysis
A6J31_RS06715	COG1380	Effector of murein hydrolase LrgA
A6J31_RS06725	COG1393	Belongs to the ArsC family
A6J31_RS06730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6J31_RS06735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A6J31_RS06750	COG1940	carbohydrate kinase activity
A6J31_RS06755	COG0346	lactoylglutathione lyase activity
A6J31_RS06770	COG1177	transmembrane transport
A6J31_RS06775	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6J31_RS06820	COG0531	amino acid
A6J31_RS06825	COG0285	dihydrofolate synthase activity
A6J31_RS06860	COG0500	methyltransferase
A6J31_RS06860	COG3615	Tellurite resistance protein tehB
A6J31_RS06880	COG0708	Exodeoxyribonuclease III
A6J31_RS06905	COG1597	lipid kinase activity
A6J31_RS06915	COG4708	membrane
A6J31_RS06925	COG0024	Methionine aminopeptidase
A6J31_RS06930	COG4109	DRTGG domain
A6J31_RS06935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J31_RS06940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A6J31_RS06945	COG2333	competence protein COMEC
A6J31_RS06945	COG0658	competence protein
A6J31_RS06950	COG1555	photosystem II stabilization
A6J31_RS06950	COG1596	polysaccharide export
A6J31_RS06955	COG0204	Acyl-transferase
A6J31_RS06960	COG0726	polysaccharide deacetylase
A6J31_RS06965	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A6J31_RS06975	COG0513	Belongs to the DEAD box helicase family
A6J31_RS07010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A6J31_RS07030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS07035	COG1126	abc transporter atp-binding protein
A6J31_RS07040	COG0765	amino acid transport
A6J31_RS07045	COG0765	amino acid transport
A6J31_RS07050	COG1181	Belongs to the D-alanine--D-alanine ligase family
A6J31_RS07060	COG2217	Heavy metal translocating P-type atpase
A6J31_RS07085	COG0159	tryptophan synthase activity
A6J31_RS07090	COG0133	tryptophan synthase activity
A6J31_RS07095	COG0135	phosphoribosylanthranilate isomerase activity
A6J31_RS07110	COG0512	Glutamine amidotransferase of anthranilate synthase
A6J31_RS07115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A6J31_RS07120	COG0287	Prephenate dehydrogenase
A6J31_RS07120	COG1605	Chorismate mutase
A6J31_RS07130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A6J31_RS07155	COG4591	ABC-type transport system involved in lipoprotein release permease component
A6J31_RS07155	COG1136	(ABC) transporter
A6J31_RS07165	COG0789	Transcriptional regulator
A6J31_RS07170	COG2176	DNA-directed DNA polymerase activity
A6J31_RS07180	COG2151	metal-sulfur cluster biosynthetic enzyme
A6J31_RS07190	COG2081	HI0933 family
A6J31_RS07215	COG1131	(ABC) transporter
A6J31_RS07220	COG0537	adenosine 5'-monophosphoramidase activity
A6J31_RS07270	COG2226	methyltransferase
A6J31_RS07275	COG0799	negative regulation of ribosome biogenesis
A6J31_RS07280	COG1335	isochorismatase
A6J31_RS07285	COG1713	HD superfamily hydrolase involved in NAD metabolism
A6J31_RS07290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A6J31_RS07295	COG1534	Rna-binding protein
A6J31_RS07300	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A6J31_RS07305	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A6J31_RS07315	COG1063	alcohol dehydrogenase
A6J31_RS07350	COG1216	Glycosyl transferase, family 2
A6J31_RS07350	COG1442	glycosyl transferase family 8
A6J31_RS07355	COG1442	glycosyl transferase family 8
A6J31_RS07360	COG2723	6-phospho-beta-galactosidase activity
A6J31_RS07365	COG1335	isochorismatase
A6J31_RS07375	COG0436	Aminotransferase
A6J31_RS07380	COG0589	response to stress
A6J31_RS07390	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A6J31_RS07400	COG1253	flavin adenine dinucleotide binding
A6J31_RS07405	COG1119	ATPase activity
A6J31_RS07420	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A6J31_RS07425	COG1242	4 iron, 4 sulfur cluster binding
A6J31_RS07430	COG3480	Lon protease (S16) C-terminal proteolytic domain
A6J31_RS07435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A6J31_RS07440	COG0742	ribosomal rna small subunit methyltransferase
A6J31_RS07455	COG1126	abc transporter atp-binding protein
A6J31_RS07460	COG0765	amino acid transport
A6J31_RS07465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS07480	COG1882	Formate acetyltransferase
A6J31_RS07500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A6J31_RS07520	COG2936	dipeptidyl-peptidase activity
A6J31_RS07550	COG1132	(ABC) transporter
A6J31_RS07555	COG1132	(ABC) transporter
A6J31_RS07575	COG4470	Protein conserved in bacteria
A6J31_RS07580	COG0737	Belongs to the 5'-nucleotidase family
A6J31_RS07595	COG0513	Belongs to the DEAD box helicase family
A6J31_RS07605	COG0768	penicillin binding
A6J31_RS07640	COG3152	Membrane
A6J31_RS07645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A6J31_RS07650	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A6J31_RS07660	COG4152	abc transporter atp-binding protein
A6J31_RS07665	COG1811	Na channel or pump
A6J31_RS07705	COG1116	anion transmembrane transporter activity
A6J31_RS07715	COG0443	Heat shock 70 kDa protein
A6J31_RS07740	COG0561	phosphatase activity
A6J31_RS07745	COG0252	asparaginase activity
A6J31_RS07750	COG3655	Transcriptional regulator
A6J31_RS07770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A6J31_RS07785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A6J31_RS07790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A6J31_RS07795	COG0653	protein targeting
A6J31_RS07805	COG1482	cell wall glycoprotein biosynthetic process
A6J31_RS07810	COG1940	carbohydrate kinase activity
A6J31_RS07815	COG1263	PTS System
A6J31_RS07815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J31_RS07815	COG2190	(PTS) system
A6J31_RS07820	COG1621	beta-fructofuranosidase activity
A6J31_RS07825	COG1609	Transcriptional regulator
A6J31_RS07840	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A6J31_RS07845	COG2131	deaminase
A6J31_RS07850	COG0006	proline dipeptidase activity
A6J31_RS07940	COG3843	relaxase mobilization nuclease domain protein
A6J31_RS07960	COG0551	DNA topoisomerase type I activity
A6J31_RS07960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A6J31_RS07975	COG2003	Belongs to the UPF0758 family
A6J31_RS08075	COG1194	a g-specific adenine glycosylase
A6J31_RS08085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J31_RS08085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J31_RS08110	COG0681	Belongs to the peptidase S26 family
A6J31_RS08115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A6J31_RS08125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A6J31_RS08135	COG0456	acetyltransferase
A6J31_RS08140	COG1214	PFAM Peptidase M22, glycoprotease
A6J31_RS08155	COG3942	CHAP domain
A6J31_RS08160	COG0174	glutamine synthetase
A6J31_RS08165	COG0789	Transcriptional regulator
A6J31_RS08175	COG0126	phosphoglycerate kinase activity
A6J31_RS08205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A6J31_RS08250	COG0084	hydrolase, TatD family'
A6J31_RS08255	COG1832	CoA-binding protein
A6J31_RS08260	COG3118	belongs to the thioredoxin family
A6J31_RS08380	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6J31_RS08395	COG0706	membrane insertase activity
A6J31_RS08445	COG4166	transmembrane transport
A6J31_RS08490	COG0756	dUTP diphosphatase activity
A6J31_RS08500	COG1053	succinate dehydrogenase
A6J31_RS08500	COG0431	NADPH-dependent FMN reductase
A6J31_RS08500	COG3976	FMN-binding domain protein
A6J31_RS08520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A6J31_RS08525	COG0457	Tetratricopeptide repeat
A6J31_RS08525	COG0705	Rhomboid family
A6J31_RS08530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A6J31_RS08555	COG2226	methyltransferase
A6J31_RS08595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J31_RS08605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6J31_RS08615	COG1363	Peptidase, m42
A6J31_RS08620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A6J31_RS08625	COG1266	CAAX protease self-immunity
A6J31_RS08680	COG1459	type II secretion system
A6J31_RS08685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A6J31_RS08720	COG0440	acetolactate synthase activity
A6J31_RS08725	COG0028	Belongs to the TPP enzyme family
A6J31_RS08730	COG0129	dihydroxy-acid dehydratase activity
A6J31_RS08735	COG1461	Dihydroxyacetone kinase
A6J31_RS08745	COG0534	Mate efflux family protein
A6J31_RS08765	COG1454	alcohol dehydrogenase
A6J31_RS08765	COG1012	belongs to the aldehyde dehydrogenase family
A6J31_RS08770	COG3590	peptidase
A6J31_RS08775	COG0366	Alpha amylase catalytic
A6J31_RS08780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J31_RS08780	COG1263	PTS System
A6J31_RS08785	COG2188	Transcriptional regulator
A6J31_RS08790	COG4475	Protein of unknown function (DUF436)
A6J31_RS08850	COG0563	adenylate kinase activity
A6J31_RS08855	COG0201	protein transport
A6J31_RS08890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A6J31_RS08960	COG0051	transcription antitermination factor activity, RNA binding
A6J31_RS08980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A6J31_RS08995	COG2855	membrane
A6J31_RS09030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A6J31_RS09035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A6J31_RS09075	COG0602	queuosine metabolic process
A6J31_RS09085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J31_RS09115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A6J31_RS09125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A6J31_RS09175	COG4974	Belongs to the 'phage' integrase family
A6J31_RS09180	COG0515	serine threonine protein kinase
A6J31_RS09180	COG2815	serine threonine protein kinase
A6J31_RS09190	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A6J31_RS09200	COG5001	Diguanylate cyclase
A6J31_RS09200	COG3300	MHYT domain
A6J31_RS09240	COG0494	nUDIX hydrolase
A6J31_RS09245	COG1695	Transcriptional regulator
A6J31_RS09260	COG1511	domain protein
A6J31_RS09260	COG1511	domain protein
A6J31_RS09270	COG3759	membrane
A6J31_RS09290	COG0305	Participates in initiation and elongation during chromosome replication
A6J31_RS09310	COG2095	MarC family integral membrane protein
A6J31_RS09325	COG0741	lytic transglycosylase activity
A6J31_RS09330	COG1388	LysM domain
A6J31_RS09330	COG3584	3D domain protein
A6J31_RS09335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A6J31_RS09350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A6J31_RS09360	COG0612	Peptidase, M16
A6J31_RS09365	COG0612	Peptidase, M16
A6J31_RS09390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J31_RS09395	COG0488	(ABC) transporter
A6J31_RS09430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6J31_RS09435	COG1475	DNA binding
A6J31_RS09450	COG0592	DNA-directed DNA polymerase activity
A6J31_RS09460	COG0012	GTP binding
A6J31_RS09470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A6J31_RS09475	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A6J31_RS09505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A6J31_RS09635	COG0436	Aminotransferase
A6J31_RS09650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6J31_RS09660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A6J31_RS09670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A6J31_RS09675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A6J31_RS09690	COG0151	Belongs to the GarS family
A6J31_RS09695	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A6J31_RS09710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A6J31_RS09725	COG4550	Control of competence regulator ComK, YlbF/YmcA
A6J31_RS09765	COG2818	Glycosylase
A6J31_RS09770	COG1546	Belongs to the CinA family
A6J31_RS09770	COG1058	Belongs to the CinA family
A6J31_RS09780	COG1393	Belongs to the ArsC family
A6J31_RS09865	COG2176	DNA-directed DNA polymerase activity
A6J31_RS09870	COG2309	aminopeptidase activity
A6J31_RS09880	COG1846	Transcriptional regulator
A6J31_RS09895	COG3634	alkyl hydroperoxide reductase activity
A6J31_RS09900	COG0450	alkyl hydroperoxide reductase
A6J31_RS09920	COG4463	regulation of RNA biosynthetic process
A6J31_RS09925	COG0542	response to heat
A6J31_RS09930	COG1686	Belongs to the peptidase S11 family
A6J31_RS09935	COG1686	Belongs to the peptidase S11 family
A6J31_RS09950	COG1045	serine acetyltransferase
A6J31_RS09960	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A6J31_RS09975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J31_RS09980	COG3688	RNA-binding protein containing a PIN domain
A6J31_RS09995	COG1476	TRANSCRIPTIONal
A6J31_RS10000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A6J31_RS10040	COG0477	Major facilitator Superfamily
A6J31_RS10070	COG4509	Sortase family
A6J31_RS10080	COG3830	Belongs to the UPF0237 family
A6J31_RS10090	COG0588	phosphoglycerate mutase activity
A6J31_RS10095	COG1876	peptidase activity
A6J31_RS10110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A6J31_RS10130	COG0351	phosphomethylpyrimidine kinase
A6J31_RS10170	COG0668	transmembrane transport
A6J31_RS10195	COG0494	nUDIX hydrolase
A6J31_RS10205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A6J31_RS10210	COG0737	Belongs to the 5'-nucleotidase family
A6J31_RS10235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A6J31_RS10275	COG1126	abc transporter atp-binding protein
A6J31_RS10280	COG0765	amino acid transport
A6J31_RS10300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A6J31_RS10310	COG0719	Fe-S assembly protein
A6J31_RS10315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A6J31_RS10340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6J31_RS10350	COG1121	(ABC) transporter
A6J31_RS10355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6J31_RS10365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J31_RS10365	COG1263	PTS System
A6J31_RS10365	COG2190	(PTS) system
A6J31_RS10380	COG1396	sequence-specific DNA binding
A6J31_RS10385	COG1132	(ABC) transporter
A6J31_RS10405	COG4589	Belongs to the CDS family
A6J31_RS10420	COG4120	Belongs to the binding-protein-dependent transport system permease family
A6J31_RS10425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6J31_RS10425	COG1116	anion transmembrane transporter activity
A6J31_RS10455	COG0564	pseudouridine synthase activity
A6J31_RS10460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J31_RS10485	COG0561	phosphatase activity
A6J31_RS10490	COG1349	DNA-binding transcription factor activity
A6J31_RS10525	COG1733	regulation of RNA biosynthetic process
A6J31_RS10540	COG3279	Response regulator of the LytR AlgR family
A6J31_RS10550	COG0789	Transcriptional regulator
A6J31_RS10555	COG1136	(ABC) transporter
A6J31_RS10555	COG0577	efflux transmembrane transporter activity
A6J31_RS10560	COG0577	efflux transmembrane transporter activity
A6J31_RS10560	COG1136	(ABC) transporter
A6J31_RS10565	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A6J31_RS10580	COG3579	cysteine-type endopeptidase activity
A6J31_RS10585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J31_RS10610	COG0116	Belongs to the methyltransferase superfamily
A6J31_RS10620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A6J31_RS10640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A6J31_RS10655	COG1254	Belongs to the acylphosphatase family
A6J31_RS10660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J31_RS10685	COG1309	transcriptional regulator
A6J31_RS10700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A6J31_RS10720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A6J31_RS10725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A6J31_RS10730	COG1187	pseudouridine synthase activity
A6J31_RS10740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J31_RS10745	COG0569	domain protein
A6J31_RS10755	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A6J31_RS10760	COG0671	phosphoesterase, PA-phosphatase related
A6J31_RS10770	COG2274	protein secretion by the type I secretion system
A6J31_RS10800	COG0804	urea catabolic process
A6J31_RS10810	COG0830	nickel cation binding
A6J31_RS10820	COG0829	nickel cation binding
A6J31_RS10825	COG0310	cobalt ion transport
A6J31_RS10830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A6J31_RS10835	COG1122	ATPase activity
A6J31_RS10840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J31_RS10845	COG1464	Belongs to the NlpA lipoprotein family
A6J31_RS10855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A6J31_RS10865	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
A6J31_RS10880	COG1122	ATPase activity
A6J31_RS10895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J31_RS10910	COG0745	RESPONSE REGULATOR receiver
A6J31_RS10915	COG5002	protein histidine kinase activity
A6J31_RS10930	COG1484	DNA-dependent DNA replication
A6J31_RS10955	COG3716	PTS system mannose fructose sorbose family IID component
A6J31_RS10960	COG3715	PTS system
A6J31_RS10975	COG3716	PTS system mannose fructose sorbose family IID component
A6J31_RS10980	COG3715	PTS system
A6J31_RS10990	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A6J31_RS10995	COG0561	phosphatase activity
A6J31_RS11000	COG2252	PERMEase
A6J31_RS11005	COG0802	atpase or kinase
A6J31_RS11010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J31_RS11015	COG1316	TRANSCRIPTIONal
A6J31_RS11025	COG0195	Participates in both transcription termination and antitermination
A6J31_RS11030	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A6J31_RS11040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A6J31_RS11065	COG2244	polysaccharide biosynthetic process
A6J31_RS11070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A6J31_RS11075	COG0626	cystathionine gamma-synthase activity
A6J31_RS11080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A6J31_RS11115	COG4471	UPF0298 protein
A6J31_RS11140	COG0410	ABC transporter
A6J31_RS11145	COG0517	IMP dehydrogenase activity
A6J31_RS11155	COG1739	Uncharacterized protein family UPF0029
A6J31_RS11160	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A6J31_RS11255	COG0527	aspartate kinase activity
A6J31_RS11260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6J31_RS11265	COG1024	Enoyl-CoA hydratase
A6J31_RS11270	COG1846	Transcriptional regulator
A6J31_RS11290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A6J31_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
A6J31_RS11300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6J31_RS11315	COG0439	Biotin carboxylase
A6J31_RS11340	COG1349	DNA-binding transcription factor activity
A6J31_RS11345	COG1105	Belongs to the carbohydrate kinase PfkB family
A6J31_RS11350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J31_RS11350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J31_RS11350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J31_RS11355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J31_RS11360	COG0285	dihydrofolate synthase activity
A6J31_RS11370	COG1104	cysteine desulfurase activity
A6J31_RS11375	COG0301	tRNA thio-modification