locus-tag	class	description
BFM96_RS00010	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BFM96_RS00015	COG2827	Endonuclease containing a URI domain
BFM96_RS00020	COG1105	Belongs to the carbohydrate kinase PfkB family
BFM96_RS00040	COG4372	Transposase
BFM96_RS00050	COG2244	polysaccharide biosynthetic process
BFM96_RS00055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFM96_RS00065	COG1227	inorganic diphosphatase activity
BFM96_RS00075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFM96_RS00080	COG0366	Alpha amylase catalytic
BFM96_RS00085	COG1263	PTS System
BFM96_RS00085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFM96_RS00090	COG2188	Transcriptional regulator
BFM96_RS00100	COG1253	flavin adenine dinucleotide binding
BFM96_RS00110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BFM96_RS00115	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFM96_RS00120	COG1126	abc transporter atp-binding protein
BFM96_RS00125	COG0765	amino acid transport
BFM96_RS00130	COG4703	Protein of unknown function (DUF1797)
BFM96_RS00135	COG0542	response to heat
BFM96_RS00155	COG0732	type I restriction modification DNA specificity domain
BFM96_RS00165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BFM96_RS00170	COG1396	sequence-specific DNA binding
BFM96_RS00180	COG1136	(ABC) transporter
BFM96_RS00180	COG0577	efflux transmembrane transporter activity
BFM96_RS00185	COG0025	NhaP-type Na H and K H
BFM96_RS00195	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BFM96_RS00200	COG1242	4 iron, 4 sulfur cluster binding
BFM96_RS00205	COG0671	phosphoesterase, PA-phosphatase related
BFM96_RS00210	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BFM96_RS00220	COG0569	domain protein
BFM96_RS00225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFM96_RS00235	COG3335	DDE superfamily endonuclease
BFM96_RS00330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BFM96_RS00335	COG1187	pseudouridine synthase activity
BFM96_RS00340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BFM96_RS00345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BFM96_RS00350	COG4974	Belongs to the 'phage' integrase family
BFM96_RS00365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BFM96_RS00370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BFM96_RS00395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFM96_RS00400	COG1254	Belongs to the acylphosphatase family
BFM96_RS00455	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFM96_RS00460	COG0154	amidase activity
BFM96_RS00465	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFM96_RS00470	COG1335	isochorismatase
BFM96_RS00475	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BFM96_RS00480	COG0436	Aminotransferase
BFM96_RS00485	COG0589	response to stress
BFM96_RS00495	COG0561	phosphatase activity
BFM96_RS00500	COG0252	asparaginase activity
BFM96_RS00505	COG1968	undecaprenyl-diphosphatase activity
BFM96_RS00510	COG4224	UPF0291 protein
BFM96_RS00515	COG0751	glycine-tRNA ligase activity
BFM96_RS00535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BFM96_RS00540	COG1283	sodium-dependent phosphate transmembrane transporter activity
BFM96_RS00555	COG5002	protein histidine kinase activity
BFM96_RS00560	COG0501	Belongs to the peptidase M48B family
BFM96_RS00565	COG1704	LemA family
BFM96_RS00580	COG0357	Ribosomal RNA small subunit methyltransferase G
BFM96_RS00590	COG1122	ATPase activity
BFM96_RS00595	COG1054	Belongs to the UPF0176 family
BFM96_RS00600	COG4720	Psort location CytoplasmicMembrane, score
BFM96_RS00615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFM96_RS00620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFM96_RS00635	COG0217	transcriptional regulatory protein
BFM96_RS00645	COG2226	methyltransferase
BFM96_RS00650	COG0799	negative regulation of ribosome biogenesis
BFM96_RS00655	COG1713	HD superfamily hydrolase involved in NAD metabolism
BFM96_RS00660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BFM96_RS00665	COG1534	Rna-binding protein
BFM96_RS00670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BFM96_RS00675	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BFM96_RS00680	COG0484	heat shock protein binding
BFM96_RS00695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BFM96_RS00700	COG1420	regulation of RNA biosynthetic process
BFM96_RS00715	COG1876	peptidase activity
BFM96_RS00720	COG0588	phosphoglycerate mutase activity
BFM96_RS00725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BFM96_RS00735	COG0736	holo-[acyl-carrier-protein] synthase activity
BFM96_RS00740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFM96_RS00745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFM96_RS00750	COG0653	protein targeting
BFM96_RS00755	COG1482	cell wall glycoprotein biosynthetic process
BFM96_RS00765	COG3583	domain protein
BFM96_RS00765	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BFM96_RS00785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFM96_RS00790	COG0768	penicillin binding
BFM96_RS00800	COG0275	rRNA processing
BFM96_RS00820	COG0765	amino acid transport
BFM96_RS00825	COG1126	abc transporter atp-binding protein
BFM96_RS00840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFM96_RS00845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BFM96_RS00850	COG0440	acetolactate synthase activity
BFM96_RS00855	COG0028	Belongs to the TPP enzyme family
BFM96_RS00865	COG2197	response regulator
BFM96_RS00870	COG4585	Histidine kinase
BFM96_RS00875	COG0842	Transport permease protein
BFM96_RS00880	COG1131	(ABC) transporter
BFM96_RS00905	COG1461	Dihydroxyacetone kinase
BFM96_RS00915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BFM96_RS00935	COG1064	alcohol dehydrogenase
BFM96_RS00945	COG3715	PTS system
BFM96_RS00950	COG3716	PTS system mannose fructose sorbose family IID component
BFM96_RS00985	COG0825	malonyl-CoA metabolic process
BFM96_RS00990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BFM96_RS00995	COG0439	Biotin carboxylase
BFM96_RS01010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFM96_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
BFM96_RS01020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BFM96_RS01025	COG2070	2-Nitropropane dioxygenase
BFM96_RS01030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFM96_RS01035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BFM96_RS01045	COG1024	Enoyl-CoA hydratase
BFM96_RS01050	COG0527	aspartate kinase activity
BFM96_RS01060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFM96_RS01060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFM96_RS01065	COG0167	dihydroorotate dehydrogenase activity
BFM96_RS01070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BFM96_RS01080	COG0668	transmembrane transport
BFM96_RS01085	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BFM96_RS01090	COG2723	6-phospho-beta-galactosidase activity
BFM96_RS01095	COG2723	6-phospho-beta-galactosidase activity
BFM96_RS01100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BFM96_RS01100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BFM96_RS01105	COG1447	Phosphotransferase system cellobiose-specific component IIA
BFM96_RS01110	COG3711	transcriptional antiterminator
BFM96_RS01115	COG3684	Belongs to the aldolase LacD family
BFM96_RS01120	COG0698	ribose 5-phosphate isomerase
BFM96_RS01130	COG1349	DNA-binding transcription factor activity
BFM96_RS01135	COG2184	nucleotidyltransferase activity
BFM96_RS01145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BFM96_RS01150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFM96_RS01155	COG4129	membrane
BFM96_RS01165	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BFM96_RS01170	COG0215	cysteine-tRNA ligase activity
BFM96_RS01180	COG1045	serine acetyltransferase
BFM96_RS01190	COG1164	Oligoendopeptidase f
BFM96_RS01195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BFM96_RS01210	COG1187	pseudouridine synthase activity
BFM96_RS01215	COG0242	peptide deformylase activity
BFM96_RS01225	COG1388	LysM domain
BFM96_RS01225	COG0860	N-Acetylmuramoyl-L-alanine amidase
BFM96_RS01450	COG0582	viral genome integration into host DNA
BFM96_RS01470	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BFM96_RS01475	COG1461	Dihydroxyacetone kinase
BFM96_RS01480	COG2376	Dihydroxyacetone kinase
BFM96_RS01490	COG2376	Dihydroxyacetone kinase
BFM96_RS01505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFM96_RS01520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BFM96_RS01530	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BFM96_RS01535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFM96_RS01550	COG4463	regulation of RNA biosynthetic process
BFM96_RS01555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BFM96_RS01560	COG0052	Belongs to the universal ribosomal protein uS2 family
BFM96_RS01565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFM96_RS01580	COG2226	methyltransferase
BFM96_RS01585	COG0705	Rhomboid family
BFM96_RS01585	COG0457	Tetratricopeptide repeat
BFM96_RS01590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BFM96_RS01595	COG1473	amidohydrolase
BFM96_RS01605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BFM96_RS01640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BFM96_RS01660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BFM96_RS01695	COG0442	prolyl-tRNA aminoacylation
BFM96_RS01700	COG0750	zinc metalloprotease
BFM96_RS01705	COG4589	Belongs to the CDS family
BFM96_RS01710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BFM96_RS01725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BFM96_RS01745	COG3425	synthase
BFM96_RS01755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFM96_RS01760	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BFM96_RS01775	COG0126	phosphoglycerate kinase activity
BFM96_RS01820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BFM96_RS01830	COG1214	PFAM Peptidase M22, glycoprotease
BFM96_RS01835	COG5503	Protein of unknown function (DUF1447)
BFM96_RS01845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFM96_RS01850	COG0085	RNA polymerase activity
BFM96_RS01885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFM96_RS01890	COG0564	pseudouridine synthase activity
BFM96_RS01915	COG1396	sequence-specific DNA binding
BFM96_RS01920	COG1131	(ABC) transporter
BFM96_RS01935	COG3443	Belongs to the bacterial solute-binding protein 9 family
BFM96_RS01935	COG0803	Belongs to the bacterial solute-binding protein 9 family
BFM96_RS01940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFM96_RS01945	COG1121	(ABC) transporter
BFM96_RS01950	COG1846	Transcriptional regulator
BFM96_RS01955	COG1216	Glycosyl transferase, family 2
BFM96_RS01960	COG0562	UDP-galactopyranose mutase
BFM96_RS01970	COG1442	glycosyl transferase family 8
BFM96_RS01975	COG1442	glycosyl transferase family 8
BFM96_RS01980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BFM96_RS01985	COG0463	Glycosyl transferase, family 2
BFM96_RS02010	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BFM96_RS02030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFM96_RS02035	COG3481	metal-dependent phosphohydrolase, HD sub domain
BFM96_RS02045	COG1564	THIamine pyrophosphokinase
BFM96_RS02055	COG1162	GTPase activity
BFM96_RS02070	COG0084	hydrolase, TatD family'
BFM96_RS02075	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BFM96_RS02095	COG0756	dUTP diphosphatase activity
BFM96_RS02110	COG1132	(ABC) transporter
BFM96_RS02115	COG1132	(ABC) transporter
BFM96_RS02120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BFM96_RS02125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BFM96_RS02130	COG3835	regulator
BFM96_RS02135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFM96_RS02140	COG1288	antiporter activity
BFM96_RS02150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFM96_RS02160	COG2801	Transposase and inactivated derivatives
BFM96_RS02300	COG0203	ribosomal protein L17
BFM96_RS02305	COG0202	RNA polymerase activity
BFM96_RS02310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BFM96_RS02315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BFM96_RS02320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BFM96_RS02330	COG0201	protein transport
BFM96_RS02345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BFM96_RS02365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BFM96_RS02370	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BFM96_RS02375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BFM96_RS02385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BFM96_RS02390	COG0255	Belongs to the universal ribosomal protein uL29 family
BFM96_RS02405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BFM96_RS02415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BFM96_RS02425	COG0088	Forms part of the polypeptide exit tunnel
BFM96_RS02430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BFM96_RS02435	COG0051	transcription antitermination factor activity, RNA binding
BFM96_RS02440	COG0572	uridine kinase
BFM96_RS02445	COG0343	queuine tRNA-ribosyltransferase activity
BFM96_RS02470	COG1832	CoA-binding protein
BFM96_RS02475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFM96_RS02475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFM96_RS02480	COG3842	ATPase activity
BFM96_RS02490	COG3759	membrane
BFM96_RS02495	COG1846	Transcriptional regulator
BFM96_RS02510	COG0546	phosphoglycolate phosphatase activity
BFM96_RS02535	COG0534	Mate efflux family protein
BFM96_RS02545	COG1396	sequence-specific DNA binding
BFM96_RS02565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFM96_RS02580	COG0395	ABC-type sugar transport system, permease component
BFM96_RS02585	COG1175	transmembrane transport
BFM96_RS02595	COG3842	ATPase activity
BFM96_RS02605	COG3458	cephalosporin-C deacetylase activity
BFM96_RS02610	COG1012	belongs to the aldehyde dehydrogenase family
BFM96_RS02610	COG1454	alcohol dehydrogenase
BFM96_RS02615	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BFM96_RS02615	COG2755	lipolytic protein G-D-S-L family
BFM96_RS02625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BFM96_RS02640	COG0138	bifunctional purine biosynthesis protein purh
BFM96_RS02645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BFM96_RS02650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BFM96_RS02660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BFM96_RS02665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BFM96_RS02670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFM96_RS02680	COG1381	Involved in DNA repair and RecF pathway recombination
BFM96_RS02685	COG0436	Aminotransferase
BFM96_RS02690	COG1132	(ABC) transporter
BFM96_RS02700	COG1396	sequence-specific DNA binding
BFM96_RS02710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFM96_RS02715	COG1472	Belongs to the glycosyl hydrolase 3 family
BFM96_RS02720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BFM96_RS02735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BFM96_RS02740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BFM96_RS02760	COG3942	CHAP domain
BFM96_RS02895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BFM96_RS02900	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BFM96_RS02905	COG0037	tRNA processing
BFM96_RS02925	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BFM96_RS02930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BFM96_RS02935	COG0193	aminoacyl-tRNA hydrolase activity
BFM96_RS02940	COG0012	GTP binding
BFM96_RS02955	COG0592	DNA-directed DNA polymerase activity
BFM96_RS02970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFM96_RS02975	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BFM96_RS03010	COG0488	(ABC) transporter
BFM96_RS03015	COG0180	Tryptophanyl-tRNA synthetase
BFM96_RS03020	COG0516	GMP reductase activity
BFM96_RS03020	COG0517	IMP dehydrogenase activity
BFM96_RS03030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BFM96_RS03035	COG2501	S4 domain
BFM96_RS03040	COG0612	Peptidase, M16
BFM96_RS03045	COG0612	Peptidase, M16
BFM96_RS03055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BFM96_RS03060	COG1122	ATPase activity
BFM96_RS03065	COG1122	ATPase activity
BFM96_RS03070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BFM96_RS03075	COG0741	lytic transglycosylase activity
BFM96_RS03090	COG1760	l-serine dehydratase
BFM96_RS03095	COG1760	l-serine dehydratase
BFM96_RS03105	COG0482	sulfurtransferase activity
BFM96_RS03110	COG2816	NAD+ diphosphatase activity
BFM96_RS03115	COG0445	tRNA wobble uridine modification
BFM96_RS03130	COG0305	Participates in initiation and elongation during chromosome replication
BFM96_RS03140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFM96_RS03145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFM96_RS03150	COG1116	anion transmembrane transporter activity
BFM96_RS03180	COG3716	PTS system mannose fructose sorbose family IID component
BFM96_RS03190	COG2222	sugar isomerase
BFM96_RS03195	COG3684	Belongs to the aldolase LacD family
BFM96_RS03205	COG2255	four-way junction helicase activity
BFM96_RS03220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BFM96_RS03245	COG1511	domain protein
BFM96_RS03255	COG1619	proteins homologs of microcin C7 resistance protein MccF
BFM96_RS03270	COG1696	Membrane protein involved in D-alanine export
BFM96_RS03280	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BFM96_RS03285	COG3764	Sortase (surface protein transpeptidase)
BFM96_RS03295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BFM96_RS03300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BFM96_RS03330	COG2151	metal-sulfur cluster biosynthetic enzyme
BFM96_RS03335	COG0129	dihydroxy-acid dehydratase activity
BFM96_RS03345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BFM96_RS03385	COG1523	belongs to the glycosyl hydrolase 13 family
BFM96_RS03390	COG1609	Transcriptional regulator
BFM96_RS03395	COG5521	maltodextrose utilization protein MalA
BFM96_RS03400	COG3833	ABC-type maltose transport systems, permease component
BFM96_RS03405	COG1175	transmembrane transport
BFM96_RS03410	COG2182	Extracellular solute-binding protein
BFM96_RS03415	COG1640	4-alpha-glucanotransferase
BFM96_RS03420	COG0058	SHG alpha-glucan phosphorylase activity
BFM96_RS03430	COG1780	Probably involved in ribonucleotide reductase function
BFM96_RS03435	COG0018	arginyl-trna synthetase
BFM96_RS03440	COG1438	arginine binding
BFM96_RS03445	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BFM96_RS03470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFM96_RS03480	COG0632	four-way junction helicase activity
BFM96_RS03485	COG2818	Glycosylase
BFM96_RS03495	COG1058	Belongs to the CinA family
BFM96_RS03495	COG1546	Belongs to the CinA family
BFM96_RS03500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BFM96_RS03505	COG1393	Belongs to the ArsC family
BFM96_RS03515	COG4472	Bacterial protein of unknown function (DUF965)
BFM96_RS03520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BFM96_RS03530	COG0285	dihydrofolate synthase activity
BFM96_RS03540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFM96_RS03550	COG1328	CTP reductase activity
BFM96_RS03575	COG4464	protein tyrosine phosphatase activity
BFM96_RS03580	COG3944	biosynthesis protein
BFM96_RS03585	COG0489	protein tyrosine kinase activity
BFM96_RS03595	COG2244	polysaccharide biosynthetic process
BFM96_RS03600	COG0562	UDP-galactopyranose mutase
BFM96_RS03625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BFM96_RS03635	COG0438	transferase activity, transferring glycosyl groups
BFM96_RS03680	COG3177	Filamentation induced by cAMP protein fic
BFM96_RS03690	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BFM96_RS03695	COG0049	tRNA binding
BFM96_RS03700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BFM96_RS03710	COG0166	Belongs to the GPI family
BFM96_RS03715	COG0697	spore germination
BFM96_RS03720	COG0594	ribonuclease P activity
BFM96_RS03725	COG0706	membrane insertase activity
BFM96_RS03740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFM96_RS03745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BFM96_RS03750	COG0459	protein refolding
BFM96_RS03760	COG3335	DDE superfamily endonuclease
BFM96_RS03785	COG4372	Transposase
BFM96_RS03815	COG3590	peptidase
BFM96_RS03835	COG0444	Belongs to the ABC transporter superfamily
BFM96_RS03855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFM96_RS03860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BFM96_RS03865	COG1882	Formate acetyltransferase
BFM96_RS03870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFM96_RS03890	COG2226	methyltransferase
BFM96_RS03895	COG2081	HI0933 family
BFM96_RS03905	COG2176	DNA-directed DNA polymerase activity
BFM96_RS03915	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BFM96_RS03940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BFM96_RS03960	COG1304	FMN binding
BFM96_RS03970	COG0789	Transcriptional regulator
BFM96_RS03975	COG0174	glutamine synthetase
BFM96_RS03990	COG1363	Peptidase, m42
BFM96_RS04005	COG2235	arginine
BFM96_RS04010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFM96_RS04015	COG0549	Belongs to the carbamate kinase family
BFM96_RS04020	COG1288	antiporter activity
BFM96_RS04030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFM96_RS04045	COG1063	alcohol dehydrogenase
BFM96_RS04055	COG4221	oxidoreductase activity
BFM96_RS04060	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFM96_RS04060	COG1902	pentaerythritol trinitrate reductase activity
BFM96_RS04075	COG1621	beta-fructofuranosidase activity
BFM96_RS04145	COG2176	DNA-directed DNA polymerase activity
BFM96_RS04155	COG2309	aminopeptidase activity
BFM96_RS04175	COG2274	protein secretion by the type I secretion system
BFM96_RS04180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFM96_RS04190	COG0737	Belongs to the 5'-nucleotidase family
BFM96_RS04200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFM96_RS04205	COG1459	type II secretion system
BFM96_RS04210	COG4537	Required for transformation and DNA binding
BFM96_RS04235	COG0827	DNA restriction-modification system
BFM96_RS04240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BFM96_RS04245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BFM96_RS04250	COG0681	Belongs to the peptidase S26 family
BFM96_RS04270	COG1193	negative regulation of DNA recombination
BFM96_RS04280	COG3118	belongs to the thioredoxin family
BFM96_RS04320	COG3335	DDE superfamily endonuclease
BFM96_RS04335	COG4372	Transposase
BFM96_RS04365	COG3335	DDE superfamily endonuclease
BFM96_RS04385	COG1464	Belongs to the NlpA lipoprotein family
BFM96_RS04390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFM96_RS04395	COG2011	ABC-type metal ion transport system permease component
BFM96_RS04405	COG2190	(PTS) system
BFM96_RS04405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFM96_RS04405	COG1263	PTS System
BFM96_RS04410	COG2272	Belongs to the type-B carboxylesterase lipase family
BFM96_RS04435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFM96_RS04455	COG0406	alpha-ribazole phosphatase activity
BFM96_RS04470	COG0360	Binds together with S18 to 16S ribosomal RNA
BFM96_RS04480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BFM96_RS04490	COG3250	beta-galactosidase activity
BFM96_RS04505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BFM96_RS04510	COG0006	proline dipeptidase activity
BFM96_RS04515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BFM96_RS04530	COG4372	Transposase
BFM96_RS04550	COG0789	Transcriptional regulator
BFM96_RS04555	COG3804	dihydrodipicolinate reductase
BFM96_RS04565	COG3830	Belongs to the UPF0237 family
BFM96_RS04570	COG2848	UPF0210 protein
BFM96_RS04575	COG0101	tRNA pseudouridine synthase activity
BFM96_RS04580	COG0351	phosphomethylpyrimidine kinase
BFM96_RS04580	COG0352	thiamine-phosphate diphosphorylase activity
BFM96_RS04585	COG4720	Psort location CytoplasmicMembrane, score
BFM96_RS04590	COG4475	Protein of unknown function (DUF436)
BFM96_RS04605	COG0544	peptidyl-prolyl cis-trans isomerase activity
BFM96_RS04610	COG3343	RNA polymerase activity
BFM96_RS04615	COG0504	CTP synthase activity
BFM96_RS04625	COG0191	fructose-bisphosphate aldolase activity
BFM96_RS04630	COG0561	phosphatase activity
BFM96_RS04635	COG3583	domain protein
BFM96_RS04640	COG2723	6-phospho-beta-galactosidase activity
BFM96_RS04645	COG0561	phosphatase activity
BFM96_RS04650	COG2252	PERMEase
BFM96_RS04660	COG0802	atpase or kinase
BFM96_RS04670	COG1316	TRANSCRIPTIONal
BFM96_RS04680	COG0537	adenosine 5'-monophosphoramidase activity
BFM96_RS04700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BFM96_RS04710	COG0195	Participates in both transcription termination and antitermination
BFM96_RS04715	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BFM96_RS04730	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BFM96_RS04735	COG4862	establishment of competence for transformation
BFM96_RS04740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFM96_RS04750	COG0719	Fe-S assembly protein
BFM96_RS04755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFM96_RS04770	COG1686	Belongs to the peptidase S11 family
BFM96_RS04775	COG0513	Belongs to the DEAD box helicase family
BFM96_RS04790	COG1126	abc transporter atp-binding protein
BFM96_RS04800	COG0492	ferredoxin-NADP+ reductase activity
BFM96_RS04805	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BFM96_RS04815	COG3579	cysteine-type endopeptidase activity
BFM96_RS04820	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BFM96_RS04825	COG4166	transmembrane transport
BFM96_RS04830	COG4166	transmembrane transport
BFM96_RS04835	COG4166	transmembrane transport
BFM96_RS04840	COG4166	transmembrane transport
BFM96_RS04845	COG4166	transmembrane transport
BFM96_RS04850	COG0601	transmembrane transport
BFM96_RS04855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFM96_RS04860	COG0444	Belongs to the ABC transporter superfamily
BFM96_RS04865	COG4608	Belongs to the ABC transporter superfamily
BFM96_RS04875	COG3335	DDE superfamily endonuclease
BFM96_RS04880	COG1609	Transcriptional regulator
BFM96_RS04885	COG1621	beta-fructofuranosidase activity
BFM96_RS04890	COG1263	PTS System
BFM96_RS04890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFM96_RS04890	COG2190	(PTS) system
BFM96_RS04895	COG1940	carbohydrate kinase activity
BFM96_RS04900	COG0242	peptide deformylase activity
BFM96_RS04905	COG1846	Transcriptional regulator
BFM96_RS04915	COG1132	(ABC) transporter
BFM96_RS04920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFM96_RS04925	COG3331	DNA recombination
BFM96_RS04930	COG4474	Belongs to the UPF0398 family
BFM96_RS04945	COG0116	Belongs to the methyltransferase superfamily
BFM96_RS04990	COG1136	(ABC) transporter
BFM96_RS05000	COG1418	mRNA catabolic process
BFM96_RS05005	COG0194	GDP metabolic process
BFM96_RS05010	COG1758	RNA polymerase activity
BFM96_RS05015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BFM96_RS05020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFM96_RS05025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFM96_RS05025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFM96_RS05030	COG0631	protein serine/threonine phosphatase activity
BFM96_RS05035	COG0515	serine threonine protein kinase
BFM96_RS05035	COG2815	serine threonine protein kinase
BFM96_RS05045	COG4585	Histidine kinase
BFM96_RS05050	COG2197	response regulator
BFM96_RS05060	COG1098	S1 RNA binding domain
BFM96_RS05070	COG1739	Uncharacterized protein family UPF0029
BFM96_RS05075	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BFM96_RS05080	COG1040	competence protein
BFM96_RS05090	COG4989	oxidoreductase activity
BFM96_RS05110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BFM96_RS05115	COG0745	RESPONSE REGULATOR receiver
BFM96_RS05135	COG3290	protein histidine kinase activity
BFM96_RS05140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFM96_RS05145	COG2274	protein secretion by the type I secretion system
BFM96_RS05165	COG1266	CAAX protease self-immunity
BFM96_RS05185	COG1131	(ABC) transporter
BFM96_RS05205	COG2190	(PTS) system
BFM96_RS05205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFM96_RS05205	COG1263	PTS System
BFM96_RS05225	COG1484	DNA-dependent DNA replication
BFM96_RS05235	COG1160	GTP binding
BFM96_RS05255	COG3557	Belongs to the UPF0374 family
BFM96_RS05260	COG2137	regulation of response to DNA damage stimulus
BFM96_RS05265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFM96_RS05270	COG0626	cystathionine gamma-synthase activity
BFM96_RS05275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BFM96_RS05285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BFM96_RS05300	COG4471	UPF0298 protein
BFM96_RS05310	COG0559	Belongs to the binding-protein-dependent transport system permease family
BFM96_RS05345	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BFM96_RS05345	COG0617	tRNA 3'-terminal CCA addition
BFM96_RS05345	COG0517	IMP dehydrogenase activity
BFM96_RS05350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BFM96_RS05355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BFM96_RS05365	COG4467	Involved in initiation control of chromosome replication
BFM96_RS05375	COG0546	phosphoglycolate phosphatase activity
BFM96_RS05380	COG0187	DNA topoisomerase II activity
BFM96_RS05385	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BFM96_RS05395	COG0028	Belongs to the TPP enzyme family
BFM96_RS05435	COG4372	Transposase
BFM96_RS05470	COG2910	NAD(P)H-binding
BFM96_RS05475	COG2514	catechol 2,3-dioxygenase activity
BFM96_RS05485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFM96_RS05490	COG4221	oxidoreductase activity
BFM96_RS05495	COG3759	membrane
BFM96_RS05550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFM96_RS05575	COG1217	gtp-binding protein TYPA
BFM96_RS05590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BFM96_RS05595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BFM96_RS05610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BFM96_RS05615	COG1799	cell septum assembly
BFM96_RS05630	COG3599	regulation of cell shape
BFM96_RS05635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BFM96_RS05645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BFM96_RS05655	COG0772	Belongs to the SEDS family
BFM96_RS05660	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BFM96_RS05675	COG1595	DNA-templated transcription, initiation
BFM96_RS05690	COG0149	triose-phosphate isomerase activity
BFM96_RS05705	COG0742	ribosomal rna small subunit methyltransferase
BFM96_RS05710	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BFM96_RS05715	COG3480	Lon protease (S16) C-terminal proteolytic domain
BFM96_RS05720	COG4470	Protein conserved in bacteria
BFM96_RS05725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BFM96_RS05740	COG1609	Transcriptional regulator
BFM96_RS05750	COG0438	transferase activity, transferring glycosyl groups
BFM96_RS05790	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BFM96_RS05810	COG2723	6-phospho-beta-galactosidase activity
BFM96_RS05815	COG4095	Psort location CytoplasmicMembrane, score
BFM96_RS05825	COG3711	transcriptional antiterminator
BFM96_RS05825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFM96_RS05830	COG1447	Phosphotransferase system cellobiose-specific component IIA
BFM96_RS05840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BFM96_RS05855	COG4122	O-methyltransferase activity
BFM96_RS05860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFM96_RS05870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BFM96_RS05880	COG1476	TRANSCRIPTIONal
BFM96_RS05910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFM96_RS05915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFM96_RS05920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BFM96_RS05925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFM96_RS05940	COG1012	belongs to the aldehyde dehydrogenase family
BFM96_RS05945	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BFM96_RS05950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFM96_RS05955	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFM96_RS05960	COG0297	glycogen (starch) synthase activity
BFM96_RS05965	COG0058	SHG alpha-glucan phosphorylase activity
BFM96_RS05975	COG0356	it plays a direct role in the translocation of protons across the membrane
BFM96_RS05980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BFM96_RS05985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFM96_RS06000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BFM96_RS06015	COG1609	Transcriptional regulator
BFM96_RS06020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BFM96_RS06025	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BFM96_RS06030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFM96_RS06040	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BFM96_RS06045	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BFM96_RS06050	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BFM96_RS06055	COG2884	Cell division ATP-binding protein ftsE
BFM96_RS06060	COG2177	Part of the ABC transporter FtsEX involved in
BFM96_RS06075	COG0772	Belongs to the SEDS family
BFM96_RS06080	COG0693	protein deglycase activity
BFM96_RS06085	COG3620	sequence-specific DNA binding
BFM96_RS06130	COG0582	viral genome integration into host DNA
BFM96_RS06135	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BFM96_RS06145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFM96_RS06155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BFM96_RS06160	COG1393	Belongs to the ArsC family
BFM96_RS06165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFM96_RS06170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BFM96_RS06175	COG0625	glutathione transferase activity
BFM96_RS06185	COG0346	lactoylglutathione lyase activity
BFM96_RS06190	COG0708	Exodeoxyribonuclease III
BFM96_RS06195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFM96_RS06195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFM96_RS06210	COG0519	Catalyzes the synthesis of GMP from XMP
BFM96_RS06220	COG4372	Transposase
BFM96_RS06240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BFM96_RS06245	COG3842	ATPase activity
BFM96_RS06255	COG1177	transmembrane transport
BFM96_RS06260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BFM96_RS06270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BFM96_RS06275	COG0571	ribonuclease III activity
BFM96_RS06280	COG1196	nuclear chromosome segregation
BFM96_RS06285	COG0561	phosphatase activity
BFM96_RS06290	COG0561	phosphatase activity
BFM96_RS06295	COG0552	protein localization to endoplasmic reticulum
BFM96_RS06300	COG1956	GAF domain-containing protein
BFM96_RS06305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BFM96_RS06330	COG0167	dihydroorotate dehydrogenase activity
BFM96_RS06360	COG4479	Belongs to the UPF0346 family
BFM96_RS06365	COG1702	phosphate starvation-inducible protein PhoH
BFM96_RS06370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFM96_RS06385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BFM96_RS06405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BFM96_RS06415	COG2814	Major facilitator Superfamily
BFM96_RS06425	COG0557	exoribonuclease II activity
BFM96_RS06445	COG1555	photosystem II stabilization
BFM96_RS06445	COG1596	polysaccharide export
BFM96_RS06450	COG2333	competence protein COMEC
BFM96_RS06450	COG0658	competence protein
BFM96_RS06460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BFM96_RS06465	COG1051	belongs to the nudix hydrolase family
BFM96_RS06475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BFM96_RS06480	COG0737	Belongs to the 5'-nucleotidase family
BFM96_RS06490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BFM96_RS06495	COG2855	membrane
BFM96_RS06615	COG1272	protein, Hemolysin III
BFM96_RS06635	COG1846	Transcriptional regulator
BFM96_RS06640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFM96_RS06695	COG1674	ftsk spoiiie
BFM96_RS06695	COG0697	spore germination
BFM96_RS06700	COG0346	lactoylglutathione lyase activity
BFM96_RS06720	COG0528	UMP kinase activity
BFM96_RS06730	COG0233	cytoplasmic translational termination
BFM96_RS06735	COG2996	Protein conserved in bacteria
BFM96_RS06740	COG1466	dna polymerase III delta subunit
BFM96_RS06745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BFM96_RS06750	COG2384	SAM-dependent methyltransferase
BFM96_RS06755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFM96_RS06760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFM96_RS06770	COG1126	abc transporter atp-binding protein
BFM96_RS06780	COG0556	nucleotide-excision repair
BFM96_RS06785	COG1131	(ABC) transporter
BFM96_RS06795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BFM96_RS06820	COG4372	Transposase
BFM96_RS06850	COG0826	peptidase U32
BFM96_RS06860	COG4443	Transcriptional Coactivator p15 (PC4)
BFM96_RS06865	COG0254	rRNA binding
BFM96_RS06870	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BFM96_RS06875	COG0716	FMN binding
BFM96_RS06880	COG1605	Chorismate mutase
BFM96_RS06880	COG0287	Prephenate dehydrogenase
BFM96_RS06885	COG0038	chloride channel
BFM96_RS06910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFM96_RS06920	COG0647	UMP catabolic process
BFM96_RS06945	COG0322	excinuclease ABC activity
BFM96_RS06960	COG1573	uracil-dna glycosylase
BFM96_RS06995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFM96_RS06995	COG0072	phenylalanine-tRNA ligase activity
BFM96_RS07005	COG0789	Transcriptional regulator
BFM96_RS07010	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BFM96_RS07015	COG1074	ATP-dependent DNA helicase activity
BFM96_RS07030	COG2059	Chromate
BFM96_RS07035	COG2059	Chromate
BFM96_RS07055	COG1121	(ABC) transporter
BFM96_RS07075	COG1131	(ABC) transporter
BFM96_RS07085	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BFM96_RS07090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BFM96_RS07100	COG1234	tRNA 3'-trailer cleavage
BFM96_RS07105	COG0300	oxidoreductase activity
BFM96_RS07115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BFM96_RS07115	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BFM96_RS07120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFM96_RS07125	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BFM96_RS07165	COG3583	domain protein
BFM96_RS07170	COG0251	oxidation-reduction process
BFM96_RS07175	COG1660	Displays ATPase and GTPase activities
BFM96_RS07180	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BFM96_RS07185	COG1481	regulation of sporulation
BFM96_RS07190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BFM96_RS07205	COG1088	dTDP-glucose 4,6-dehydratase activity
BFM96_RS07210	COG0463	Glycosyl transferase, family 2
BFM96_RS07215	COG1216	Glycosyl transferase, family 2
BFM96_RS07220	COG1216	Glycosyl transferase, family 2
BFM96_RS07235	COG1442	glycosyl transferase family 8
BFM96_RS07235	COG1216	Glycosyl transferase, family 2
BFM96_RS07245	COG1091	dTDP-4-dehydrorhamnose reductase activity
BFM96_RS07255	COG1215	transferase activity, transferring glycosyl groups
BFM96_RS07285	COG1368	sulfuric ester hydrolase activity
BFM96_RS07300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BFM96_RS07310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BFM96_RS07320	COG0492	ferredoxin-NADP+ reductase activity
BFM96_RS07330	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BFM96_RS07340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BFM96_RS07350	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BFM96_RS07360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BFM96_RS07365	COG0196	riboflavin kinase activity
BFM96_RS07370	COG1393	Belongs to the ArsC family
BFM96_RS07375	COG4476	Belongs to the UPF0223 family
BFM96_RS07380	COG0483	inositol monophosphate 1-phosphatase activity
BFM96_RS07385	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BFM96_RS07385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFM96_RS07395	COG0573	inorganic phosphate transmembrane transporter activity
BFM96_RS07400	COG0581	inorganic phosphate transmembrane transporter activity
BFM96_RS07405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BFM96_RS07410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BFM96_RS07415	COG0704	Plays a role in the regulation of phosphate uptake
BFM96_RS07420	COG0038	chloride channel
BFM96_RS07435	COG0745	RESPONSE REGULATOR receiver
BFM96_RS07440	COG5002	protein histidine kinase activity
BFM96_RS07445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BFM96_RS07450	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFM96_RS07455	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BFM96_RS07475	COG0813	purine-nucleoside phosphorylase activity
BFM96_RS07485	COG0583	DNA-binding transcription factor activity
BFM96_RS07490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BFM96_RS07495	COG0564	pseudouridine synthase activity
BFM96_RS07500	COG1115	amino acid carrier protein
BFM96_RS07515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BFM96_RS07520	COG2824	Alkylphosphonate utilization operon protein PhnA
BFM96_RS07530	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BFM96_RS07540	COG0540	Belongs to the ATCase OTCase family
BFM96_RS07545	COG0505	Belongs to the CarA family
BFM96_RS07570	COG3321	synthase
BFM96_RS07570	COG1028	Short-chain dehydrogenase reductase Sdr
BFM96_RS07570	COG0604	alcohol dehydrogenase
BFM96_RS07575	COG0596	Alpha beta hydrolase
BFM96_RS07580	COG1028	Short-chain dehydrogenase reductase Sdr
BFM96_RS07585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BFM96_RS07590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFM96_RS07595	COG3711	transcriptional antiterminator
BFM96_RS07600	COG0110	maltose O-acetyltransferase activity
BFM96_RS07605	COG0534	Mate efflux family protein
BFM96_RS07625	COG1942	4-Oxalocrotonate Tautomerase
BFM96_RS07630	COG1435	thymidine kinase activity
BFM96_RS07635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BFM96_RS07640	COG2890	protein-(glutamine-N5) methyltransferase activity
BFM96_RS07650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BFM96_RS07660	COG0741	lytic transglycosylase activity
BFM96_RS07665	COG4221	oxidoreductase activity
BFM96_RS07685	COG1970	mechanosensitive ion channel activity
BFM96_RS07690	COG0358	DNA primase activity
BFM96_RS07695	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BFM96_RS07700	COG2151	metal-sulfur cluster biosynthetic enzyme
BFM96_RS07710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFM96_RS07715	COG4684	Psort location CytoplasmicMembrane, score
BFM96_RS07720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BFM96_RS07730	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BFM96_RS07755	COG0758	DNA mediated transformation
BFM96_RS07760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BFM96_RS07765	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BFM96_RS07770	COG0789	Transcriptional regulator
BFM96_RS07815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BFM96_RS07820	COG0022	dehydrogenase e1 component
BFM96_RS07825	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFM96_RS07830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFM96_RS07835	COG0095	Lipoate-protein ligase
BFM96_RS07855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BFM96_RS07870	COG1307	EDD domain protein, DegV family
BFM96_RS07875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BFM96_RS07880	COG0617	tRNA 3'-terminal CCA addition
BFM96_RS07885	COG0488	(ABC) transporter
BFM96_RS07895	COG1940	carbohydrate kinase activity
BFM96_RS07900	COG0745	RESPONSE REGULATOR receiver
BFM96_RS07905	COG5002	protein histidine kinase activity
BFM96_RS07910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BFM96_RS07930	COG1072	(Pantothenic acid kinase))
BFM96_RS07935	COG2813	Specifically methylates the guanine in position
BFM96_RS07945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BFM96_RS07950	COG0295	cytidine deaminase activity
BFM96_RS07955	COG1744	ABC transporter substrate-binding protein PnrA-like
BFM96_RS07960	COG3845	ABC transporter
BFM96_RS07965	COG4603	Belongs to the binding-protein-dependent transport system permease family
BFM96_RS07970	COG1079	Belongs to the binding-protein-dependent transport system permease family
BFM96_RS07980	COG2188	Transcriptional regulator
BFM96_RS07995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BFM96_RS08015	COG4974	Belongs to the 'phage' integrase family
BFM96_RS08035	COG4372	Transposase
BFM96_RS08070	COG0444	Belongs to the ABC transporter superfamily
BFM96_RS08075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFM96_RS08080	COG0601	transmembrane transport
BFM96_RS08085	COG0747	negative chemotaxis
BFM96_RS08090	COG1902	pentaerythritol trinitrate reductase activity
BFM96_RS08100	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BFM96_RS08105	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BFM96_RS08110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BFM96_RS08115	COG0113	porphobilinogen synthase activity
BFM96_RS08125	COG0181	hydroxymethylbilane synthase activity
BFM96_RS08130	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BFM96_RS08135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFM96_RS08135	COG1648	precorrin-2 dehydrogenase activity
BFM96_RS08140	COG2096	Adenosyltransferase
BFM96_RS08145	COG1492	cobalamin metabolic process
BFM96_RS08165	COG0310	cobalt ion transport
BFM96_RS08215	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BFM96_RS08230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BFM96_RS08235	COG1797	cobyrinic acid a,c-diamide synthase activity
BFM96_RS08245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFM96_RS08255	COG1126	abc transporter atp-binding protein
BFM96_RS08260	COG0765	amino acid transport
BFM96_RS08275	COG0083	homoserine kinase activity
BFM96_RS08285	COG0726	polysaccharide deacetylase
BFM96_RS08290	COG3764	Sortase (surface protein transpeptidase)
BFM96_RS08295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BFM96_RS08300	COG0039	L-malate dehydrogenase activity
BFM96_RS08305	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BFM96_RS08310	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BFM96_RS08315	COG2003	Belongs to the UPF0758 family
BFM96_RS08330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BFM96_RS08335	COG4766	ethanolamine catabolic process
BFM96_RS08340	COG3192	ethanolamine utilization protein
BFM96_RS08355	COG4869	propanediol catabolic process
BFM96_RS08375	COG1012	belongs to the aldehyde dehydrogenase family
BFM96_RS08375	COG1454	alcohol dehydrogenase
BFM96_RS08380	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BFM96_RS08385	COG4816	utilization protein
BFM96_RS08390	COG4302	ethanolamine ammonia-lyase activity
BFM96_RS08395	COG4303	Ethanolamine ammonia lyase large subunit
BFM96_RS08430	COG5002	protein histidine kinase activity
BFM96_RS08435	COG0745	RESPONSE REGULATOR receiver
BFM96_RS08440	COG1136	(ABC) transporter
BFM96_RS08460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFM96_RS08480	COG3118	belongs to the thioredoxin family
BFM96_RS08490	COG2096	Adenosyltransferase
BFM96_RS08505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFM96_RS08520	COG1132	(ABC) transporter
BFM96_RS08525	COG1132	(ABC) transporter
BFM96_RS08535	COG0789	Transcriptional regulator
BFM96_RS08550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFM96_RS08555	COG2723	6-phospho-beta-galactosidase activity
BFM96_RS08560	COG2814	Major facilitator Superfamily
BFM96_RS08570	COG0583	DNA-binding transcription factor activity
BFM96_RS08575	COG1194	a g-specific adenine glycosylase
BFM96_RS08580	COG0280	phosphate acetyltransferase
BFM96_RS08585	COG0564	pseudouridine synthase activity
BFM96_RS08595	COG2357	RelA SpoT domain protein
BFM96_RS08605	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFM96_RS08610	COG1104	cysteine desulfurase activity
BFM96_RS08625	COG4372	Transposase
BFM96_RS08650	COG4372	Transposase
BFM96_RS08690	COG0469	pyruvate kinase activity
BFM96_RS08695	COG0205	6-phosphofructokinase activity
BFM96_RS08705	COG1725	Transcriptional regulator
BFM96_RS08710	COG1131	(ABC) transporter
BFM96_RS08735	COG1304	FMN binding
BFM96_RS08745	COG2315	Protein conserved in bacteria
BFM96_RS08750	COG1174	glycine betaine transport
BFM96_RS08770	COG1846	Transcriptional regulator
BFM96_RS08800	COG0488	(ABC) transporter
BFM96_RS08805	COG2814	Major facilitator Superfamily
BFM96_RS08815	COG0488	(ABC) transporter
BFM96_RS08850	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BFM96_RS08860	COG3091	SprT-like family
BFM96_RS08865	COG2183	response to ionizing radiation
BFM96_RS08870	COG0701	Predicted permease
BFM96_RS08875	COG3689	TIGRFAM TIGR03943 family protein
BFM96_RS08880	COG2274	protein secretion by the type I secretion system
BFM96_RS08900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BFM96_RS08910	COG3443	Belongs to the bacterial solute-binding protein 9 family
BFM96_RS08910	COG0803	Belongs to the bacterial solute-binding protein 9 family
BFM96_RS08915	COG0336	Belongs to the RNA methyltransferase TrmD family
BFM96_RS08920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BFM96_RS08930	COG1837	Belongs to the UPF0109 family
BFM96_RS08940	COG1523	belongs to the glycosyl hydrolase 13 family
BFM96_RS08945	COG1597	lipid kinase activity
BFM96_RS08950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BFM96_RS08960	COG4708	membrane
BFM96_RS08965	COG2246	polysaccharide biosynthetic process
BFM96_RS08990	COG0024	Methionine aminopeptidase
BFM96_RS08995	COG4109	DRTGG domain
BFM96_RS09005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFM96_RS09010	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BFM96_RS09025	COG4152	abc transporter atp-binding protein
BFM96_RS09030	COG2131	deaminase
BFM96_RS09045	COG1363	Peptidase, m42
BFM96_RS09050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BFM96_RS09070	COG4372	Transposase
BFM96_RS09240	COG1196	nuclear chromosome segregation
BFM96_RS09270	COG3620	sequence-specific DNA binding
BFM96_RS09290	COG1674	ftsk spoiiie
BFM96_RS09300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFM96_RS09310	COG0077	Prephenate dehydratase
BFM96_RS09315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BFM96_RS09325	COG3679	Belongs to the UPF0342 family
BFM96_RS09330	COG0287	Prephenate dehydrogenase
BFM96_RS09335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BFM96_RS09340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BFM96_RS09350	COG0710	3-dehydroquinate dehydratase activity
BFM96_RS09355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFM96_RS09360	COG1368	sulfuric ester hydrolase activity
BFM96_RS09365	COG0488	(ABC) transporter
BFM96_RS09385	COG0438	transferase activity, transferring glycosyl groups
BFM96_RS09390	COG0653	protein targeting
BFM96_RS09425	COG1442	glycosyl transferase family 8
BFM96_RS09435	COG3335	DDE superfamily endonuclease
BFM96_RS09440	COG1442	glycosyl transferase family 8
BFM96_RS09445	COG1442	glycosyl transferase family 8
BFM96_RS09465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BFM96_RS09475	COG0577	efflux transmembrane transporter activity
BFM96_RS09480	COG1136	(ABC) transporter
BFM96_RS09485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFM96_RS09490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFM96_RS09495	COG1268	BioY protein
BFM96_RS09500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFM96_RS09510	COG3142	Participates in the control of copper homeostasis
BFM96_RS09515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFM96_RS09525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BFM96_RS09540	COG0596	Alpha beta hydrolase
BFM96_RS09545	COG0301	tRNA thio-modification
BFM96_RS09550	COG1104	cysteine desulfurase activity
BFM96_RS09555	COG3527	Alpha-acetolactate decarboxylase
BFM96_RS09560	COG0457	Tetratricopeptide repeat
BFM96_RS09565	COG0628	permease
BFM96_RS09570	COG2706	6-phosphogluconolactonase activity
BFM96_RS09575	COG2040	homocysteine
BFM96_RS09580	COG0833	amino acid
BFM96_RS09590	COG1011	Hydrolase
BFM96_RS09680	COG0740	serine-type endopeptidase activity
BFM96_RS09685	COG4695	Portal protein
BFM96_RS09800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFM96_RS09800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFM96_RS09885	COG2801	Transposase and inactivated derivatives
BFM96_RS09940	COG0481	GTPase activity
BFM96_RS09950	COG1187	pseudouridine synthase activity
BFM96_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
BFM96_RS09985	COG0531	amino acid
BFM96_RS10005	COG0577	efflux transmembrane transporter activity
BFM96_RS10010	COG1136	(ABC) transporter
BFM96_RS10015	COG0577	efflux transmembrane transporter activity
BFM96_RS10020	COG2205	protein histidine kinase activity
BFM96_RS10025	COG0745	RESPONSE REGULATOR receiver
BFM96_RS10035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFM96_RS10040	COG2217	Heavy metal translocating P-type atpase
BFM96_RS10065	COG1078	dGTPase activity
BFM96_RS10075	COG2348	transferase activity, transferring amino-acyl groups
BFM96_RS10100	COG0561	phosphatase activity
BFM96_RS10105	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFM96_RS10135	COG0066	3-isopropylmalate dehydratase activity
BFM96_RS10195	COG0726	polysaccharide deacetylase
BFM96_RS10205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFM96_RS10210	COG0017	Asparaginyl-tRNA synthetase
BFM96_RS10215	COG0436	Aminotransferase
BFM96_RS10230	COG2972	Histidine kinase
BFM96_RS10235	COG4753	response regulator
BFM96_RS10235	COG2207	Transcriptional regulator
BFM96_RS10240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFM96_RS10240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFM96_RS10245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFM96_RS10255	COG0785	Cytochrome C biogenesis protein
BFM96_RS10260	COG1114	Component of the transport system for branched-chain amino acids
BFM96_RS10270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFM96_RS10270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFM96_RS10270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFM96_RS10275	COG1105	Belongs to the carbohydrate kinase PfkB family
BFM96_RS10280	COG1349	DNA-binding transcription factor activity
BFM96_RS10285	COG0539	negative regulation of cytoplasmic translation
BFM96_RS10305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFM96_RS10310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BFM96_RS10315	COG2184	nucleotidyltransferase activity
BFM96_RS10320	COG0187	DNA topoisomerase II activity
BFM96_RS10335	COG0560	Phosphoserine phosphatase
BFM96_RS10340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFM96_RS10345	COG0805	protein transport
BFM96_RS10350	COG0672	)-iron permease
BFM96_RS10355	COG2837	iron assimilation
BFM96_RS10360	COG2822	iron ion transport
BFM96_RS10365	COG2807	transmembrane transport
BFM96_RS10370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFM96_RS10385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BFM96_RS10390	COG3442	glutamine amidotransferase
BFM96_RS10410	COG3335	DDE superfamily endonuclease
BFM96_RS10440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFM96_RS10445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BFM96_RS10460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFM96_RS10470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFM96_RS10480	COG1755	Isoprenylcysteine carboxyl methyltransferase
BFM96_RS10490	COG0640	Transcriptional regulator
BFM96_RS10495	COG0513	Belongs to the DEAD box helicase family
BFM96_RS10510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BFM96_RS10520	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BFM96_RS10535	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BFM96_RS10545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BFM96_RS10550	COG0768	penicillin binding
BFM96_RS10575	COG0776	regulation of translation
BFM96_RS10580	COG1307	EDD domain protein, DegV family
BFM96_RS10590	COG0497	DNA recombination
BFM96_RS10595	COG1438	arginine binding
BFM96_RS10600	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BFM96_RS10610	COG1722	exodeoxyribonuclease VII activity
BFM96_RS10615	COG1570	exodeoxyribonuclease VII activity
BFM96_RS10620	COG0628	permease
BFM96_RS10625	COG1119	ATPase activity
BFM96_RS10630	COG0693	protein deglycase activity
BFM96_RS10640	COG0204	Acyl-transferase
BFM96_RS10645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BFM96_RS10650	COG1125	glycine betaine transport
BFM96_RS10650	COG0517	IMP dehydrogenase activity
BFM96_RS10655	COG1174	glycine betaine transport
BFM96_RS10675	COG2207	Transcriptional regulator