locus-tag	class	description
FPL13_RS00020	COG0602	queuosine metabolic process
FPL13_RS00055	COG5002	protein histidine kinase activity
FPL13_RS00065	COG2190	(PTS) system
FPL13_RS00065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL13_RS00065	COG1263	PTS System
FPL13_RS00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPL13_RS00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPL13_RS00085	COG1832	CoA-binding protein
FPL13_RS00100	COG0343	queuine tRNA-ribosyltransferase activity
FPL13_RS00105	COG0572	uridine kinase
FPL13_RS00115	COG0051	transcription antitermination factor activity, RNA binding
FPL13_RS00120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FPL13_RS00125	COG0088	Forms part of the polypeptide exit tunnel
FPL13_RS00130	COG0089	rRNA binding
FPL13_RS00135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FPL13_RS00145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FPL13_RS00150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FPL13_RS00155	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FPL13_RS00160	COG0255	Belongs to the universal ribosomal protein uL29 family
FPL13_RS00170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FPL13_RS00175	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FPL13_RS00180	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FPL13_RS00185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FPL13_RS00190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FPL13_RS00195	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FPL13_RS00205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FPL13_RS00210	COG1841	ribosomal large subunit assembly
FPL13_RS00215	COG0200	Binds to the 23S rRNA
FPL13_RS00220	COG0201	protein transport
FPL13_RS00225	COG0563	adenylate kinase activity
FPL13_RS00230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FPL13_RS00235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FPL13_RS00240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FPL13_RS00245	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FPL13_RS00250	COG0202	RNA polymerase activity
FPL13_RS00255	COG0203	ribosomal protein L17
FPL13_RS00265	COG0052	Belongs to the universal ribosomal protein uS2 family
FPL13_RS00270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FPL13_RS00280	COG4463	regulation of RNA biosynthetic process
FPL13_RS00310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FPL13_RS00315	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FPL13_RS00330	COG1063	alcohol dehydrogenase
FPL13_RS00345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FPL13_RS00365	COG1396	sequence-specific DNA binding
FPL13_RS00375	COG0166	Belongs to the GPI family
FPL13_RS00385	COG0594	ribonuclease P activity
FPL13_RS00405	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FPL13_RS00410	COG0084	hydrolase, TatD family'
FPL13_RS00430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FPL13_RS00445	COG1162	GTPase activity
FPL13_RS00455	COG1564	THIamine pyrophosphokinase
FPL13_RS00465	COG3481	metal-dependent phosphohydrolase, HD sub domain
FPL13_RS00470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FPL13_RS00480	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FPL13_RS00485	COG0049	tRNA binding
FPL13_RS00490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FPL13_RS00540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FPL13_RS00545	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FPL13_RS00550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FPL13_RS00560	COG0756	dUTP diphosphatase activity
FPL13_RS00580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPL13_RS00585	COG3414	Phosphotransferase system galactitol-specific IIB component
FPL13_RS00600	COG0235	Class ii aldolase
FPL13_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPL13_RS00610	COG2171	N-acyltransferase activity
FPL13_RS00615	COG1473	amidohydrolase
FPL13_RS00630	COG2226	methyltransferase
FPL13_RS00635	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FPL13_RS00645	COG0085	RNA polymerase activity
FPL13_RS00650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FPL13_RS00655	COG0126	phosphoglycerate kinase activity
FPL13_RS00665	COG3942	CHAP domain
FPL13_RS00675	COG0789	Transcriptional regulator
FPL13_RS00680	COG0174	glutamine synthetase
FPL13_RS00690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FPL13_RS00700	COG4537	Required for transformation and DNA binding
FPL13_RS00730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FPL13_RS00745	COG3037	sugar-specific permease SgaT UlaA
FPL13_RS00755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPL13_RS00765	COG3623	hexulose-6-phosphate isomerase
FPL13_RS00785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FPL13_RS00800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FPL13_RS00805	COG4589	Belongs to the CDS family
FPL13_RS00810	COG0750	zinc metalloprotease
FPL13_RS00815	COG0442	prolyl-tRNA aminoacylation
FPL13_RS00825	COG0285	dihydrofolate synthase activity
FPL13_RS00835	COG1363	Peptidase, m42
FPL13_RS00845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPL13_RS00850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPL13_RS00865	COG4585	Histidine kinase
FPL13_RS00870	COG2197	response regulator
FPL13_RS00890	COG3715	PTS system
FPL13_RS00895	COG3716	PTS system mannose fructose sorbose family IID component
FPL13_RS00905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FPL13_RS00910	COG0459	protein refolding
FPL13_RS00920	COG1428	Deoxynucleoside kinase
FPL13_RS00925	COG1418	mRNA catabolic process
FPL13_RS00940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FPL13_RS00950	COG1051	belongs to the nudix hydrolase family
FPL13_RS00960	COG2264	protein methyltransferase activity
FPL13_RS00965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FPL13_RS00980	COG1490	D-aminoacyl-tRNA deacylase activity
FPL13_RS01005	COG3590	peptidase
FPL13_RS01010	COG4988	ABC transporter
FPL13_RS01015	COG1132	(ABC) transporter
FPL13_RS01045	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPL13_RS01060	COG1523	belongs to the glycosyl hydrolase 13 family
FPL13_RS01065	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FPL13_RS01075	COG2176	DNA-directed DNA polymerase activity
FPL13_RS01165	COG3118	belongs to the thioredoxin family
FPL13_RS01170	COG1164	Oligoendopeptidase f
FPL13_RS01175	COG1185	polyribonucleotide nucleotidyltransferase activity
FPL13_RS01180	COG1045	serine acetyltransferase
FPL13_RS01185	COG0215	cysteine-tRNA ligase activity
FPL13_RS01190	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FPL13_RS01200	COG3842	ATPase activity
FPL13_RS01235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FPL13_RS01240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FPL13_RS01260	COG1881	PFAM PEBP family protein
FPL13_RS01295	COG3830	Belongs to the UPF0237 family
FPL13_RS01300	COG2848	UPF0210 protein
FPL13_RS01305	COG0588	phosphoglycerate mutase activity
FPL13_RS01310	COG0588	phosphoglycerate mutase activity
FPL13_RS01330	COG1420	regulation of RNA biosynthetic process
FPL13_RS01335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FPL13_RS01340	COG0443	Heat shock 70 kDa protein
FPL13_RS01350	COG0484	heat shock protein binding
FPL13_RS01365	COG0101	tRNA pseudouridine synthase activity
FPL13_RS01370	COG0351	phosphomethylpyrimidine kinase
FPL13_RS01375	COG4720	Psort location CytoplasmicMembrane, score
FPL13_RS01380	COG4475	Protein of unknown function (DUF436)
FPL13_RS01385	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPL13_RS01390	COG3343	RNA polymerase activity
FPL13_RS01395	COG0504	CTP synthase activity
FPL13_RS01405	COG4166	transmembrane transport
FPL13_RS01410	COG4166	transmembrane transport
FPL13_RS01420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPL13_RS01425	COG0444	Belongs to the ABC transporter superfamily
FPL13_RS01430	COG4608	Belongs to the ABC transporter superfamily
FPL13_RS01435	COG0561	phosphatase activity
FPL13_RS01440	COG1609	Transcriptional regulator
FPL13_RS01445	COG1621	beta-fructofuranosidase activity
FPL13_RS01450	COG2190	(PTS) system
FPL13_RS01450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL13_RS01450	COG1263	PTS System
FPL13_RS01455	COG1940	carbohydrate kinase activity
FPL13_RS01460	COG0242	peptide deformylase activity
FPL13_RS01475	COG1132	(ABC) transporter
FPL13_RS01480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL13_RS01485	COG1447	Phosphotransferase system cellobiose-specific component IIA
FPL13_RS01490	COG2723	6-phospho-beta-galactosidase activity
FPL13_RS01495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL13_RS01500	COG2188	Transcriptional regulator
FPL13_RS01505	COG1482	cell wall glycoprotein biosynthetic process
FPL13_RS01520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FPL13_RS01525	COG0736	holo-[acyl-carrier-protein] synthase activity
FPL13_RS01530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FPL13_RS01535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FPL13_RS01540	COG0252	asparaginase activity
FPL13_RS01550	COG0589	response to stress
FPL13_RS01555	COG0436	Aminotransferase
FPL13_RS01560	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FPL13_RS01565	COG1335	isochorismatase
FPL13_RS01570	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FPL13_RS01575	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FPL13_RS01580	COG0154	amidase activity
FPL13_RS01585	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FPL13_RS01600	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FPL13_RS01605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FPL13_RS01610	COG1534	Rna-binding protein
FPL13_RS01615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FPL13_RS01620	COG1713	HD superfamily hydrolase involved in NAD metabolism
FPL13_RS01625	COG1335	isochorismatase
FPL13_RS01630	COG0799	negative regulation of ribosome biogenesis
FPL13_RS01635	COG2226	methyltransferase
FPL13_RS01645	COG1323	Belongs to the UPF0348 family
FPL13_RS01650	COG0217	transcriptional regulatory protein
FPL13_RS01655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPL13_RS01660	COG1464	Belongs to the NlpA lipoprotein family
FPL13_RS01665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPL13_RS01670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FPL13_RS01755	COG4720	Psort location CytoplasmicMembrane, score
FPL13_RS01765	COG1122	ATPase activity
FPL13_RS01775	COG4221	oxidoreductase activity
FPL13_RS01780	COG1442	glycosyl transferase family 8
FPL13_RS01785	COG0357	Ribosomal RNA small subunit methyltransferase G
FPL13_RS01790	COG1704	LemA family
FPL13_RS01795	COG0501	Belongs to the peptidase M48B family
FPL13_RS01810	COG1399	metal-binding, possibly nucleic acid-binding protein
FPL13_RS01815	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FPL13_RS01820	COG0745	RESPONSE REGULATOR receiver
FPL13_RS01825	COG2190	(PTS) system
FPL13_RS01825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL13_RS01825	COG1263	PTS System
FPL13_RS01835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FPL13_RS01845	COG1484	DNA-dependent DNA replication
FPL13_RS01855	COG1160	GTP binding
FPL13_RS01865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FPL13_RS01875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FPL13_RS01890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FPL13_RS01920	COG1254	Belongs to the acylphosphatase family
FPL13_RS01925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPL13_RS01950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FPL13_RS01970	COG4974	Belongs to the 'phage' integrase family
FPL13_RS01975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FPL13_RS01980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FPL13_RS01985	COG1187	pseudouridine synthase activity
FPL13_RS01990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FPL13_RS02015	COG0569	domain protein
FPL13_RS02030	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FPL13_RS02035	COG0671	phosphoesterase, PA-phosphatase related
FPL13_RS02045	COG1242	4 iron, 4 sulfur cluster binding
FPL13_RS02050	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FPL13_RS02060	COG0025	NhaP-type Na H and K H
FPL13_RS02070	COG0494	nUDIX hydrolase
FPL13_RS02090	COG0542	response to heat
FPL13_RS02095	COG4703	Protein of unknown function (DUF1797)
FPL13_RS02125	COG1136	(ABC) transporter
FPL13_RS02130	COG0577	efflux transmembrane transporter activity
FPL13_RS02140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FPL13_RS02145	COG1609	Transcriptional regulator
FPL13_RS02155	COG1175	transmembrane transport
FPL13_RS02160	COG0395	ABC-type sugar transport system, permease component
FPL13_RS02165	COG1621	beta-fructofuranosidase activity
FPL13_RS02185	COG1570	exodeoxyribonuclease VII activity
FPL13_RS02190	COG1722	exodeoxyribonuclease VII activity
FPL13_RS02200	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FPL13_RS02205	COG1438	arginine binding
FPL13_RS02210	COG0497	DNA recombination
FPL13_RS02215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FPL13_RS02220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPL13_RS02225	COG4604	ABC transporter, ATP-binding protein
FPL13_RS02230	COG4605	iron ion homeostasis
FPL13_RS02235	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL13_RS02240	COG1307	EDD domain protein, DegV family
FPL13_RS02255	COG0588	phosphoglycerate mutase activity
FPL13_RS02260	COG0768	penicillin binding
FPL13_RS02265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FPL13_RS02270	COG1181	Belongs to the D-alanine--D-alanine ligase family
FPL13_RS02275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FPL13_RS02295	COG3620	sequence-specific DNA binding
FPL13_RS02315	COG0513	Belongs to the DEAD box helicase family
FPL13_RS02325	COG1349	DNA-binding transcription factor activity
FPL13_RS02330	COG0698	ribose 5-phosphate isomerase
FPL13_RS02345	COG1755	Isoprenylcysteine carboxyl methyltransferase
FPL13_RS02350	COG3711	transcriptional antiterminator
FPL13_RS02360	COG1447	Phosphotransferase system cellobiose-specific component IIA
FPL13_RS02365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL13_RS02365	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL13_RS02370	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FPL13_RS02375	COG2827	Endonuclease containing a URI domain
FPL13_RS02380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FPL13_RS02385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FPL13_RS02390	COG0204	Acyl-transferase
FPL13_RS02400	COG1476	TRANSCRIPTIONal
FPL13_RS02415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPL13_RS02425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FPL13_RS02435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FPL13_RS02440	COG0322	excinuclease ABC activity
FPL13_RS02450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPL13_RS02460	COG1573	uracil-dna glycosylase
FPL13_RS02470	COG1732	Glycine betaine
FPL13_RS02475	COG1125	glycine betaine transport
FPL13_RS02500	COG0254	rRNA binding
FPL13_RS02505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPL13_RS02510	COG0716	FMN binding
FPL13_RS02530	COG1309	transcriptional regulator
FPL13_RS02550	COG1959	2 iron, 2 sulfur cluster binding
FPL13_RS02555	COG2910	NAD(P)H-binding
FPL13_RS02570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FPL13_RS02575	COG0406	alpha-ribazole phosphatase activity
FPL13_RS02580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FPL13_RS02595	COG0772	Belongs to the SEDS family
FPL13_RS02620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FPL13_RS02635	COG0006	proline dipeptidase activity
FPL13_RS02640	COG1609	Transcriptional regulator
FPL13_RS02650	COG0438	transferase activity, transferring glycosyl groups
FPL13_RS02660	COG0745	RESPONSE REGULATOR receiver
FPL13_RS02665	COG5002	protein histidine kinase activity
FPL13_RS02670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FPL13_RS02675	COG2832	Protein of unknown function (DUF454)
FPL13_RS02680	COG0571	ribonuclease III activity
FPL13_RS02685	COG1196	nuclear chromosome segregation
FPL13_RS02690	COG0561	phosphatase activity
FPL13_RS02695	COG0561	phosphatase activity
FPL13_RS02700	COG0552	protein localization to endoplasmic reticulum
FPL13_RS02705	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FPL13_RS02710	COG0477	Major facilitator Superfamily
FPL13_RS02715	COG3689	TIGRFAM TIGR03943 family protein
FPL13_RS02720	COG0701	Predicted permease
FPL13_RS02750	COG2183	response to ionizing radiation
FPL13_RS02755	COG3091	SprT-like family
FPL13_RS02770	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FPL13_RS02775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FPL13_RS02800	COG0826	peptidase U32
FPL13_RS02825	COG0488	(ABC) transporter
FPL13_RS02835	COG3442	glutamine amidotransferase
FPL13_RS02840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FPL13_RS02845	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FPL13_RS02855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPL13_RS02860	COG0560	Phosphoserine phosphatase
FPL13_RS02885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FPL13_RS02895	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FPL13_RS02905	COG0346	lactoylglutathione lyase activity
FPL13_RS02910	COG0726	polysaccharide deacetylase
FPL13_RS02920	COG0673	inositol 2-dehydrogenase activity
FPL13_RS02925	COG0572	uridine kinase
FPL13_RS02935	COG2195	Cleaves the N-terminal amino acid of tripeptides
FPL13_RS02940	COG0561	phosphatase activity
FPL13_RS02945	COG0481	GTPase activity
FPL13_RS02955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FPL13_RS02960	COG3842	ATPase activity
FPL13_RS02965	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPL13_RS02970	COG1177	transmembrane transport
FPL13_RS02985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FPL13_RS02985	COG0574	Belongs to the PEP-utilizing enzyme family
FPL13_RS02990	COG0517	IMP dehydrogenase activity
FPL13_RS02995	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FPL13_RS03005	COG1104	cysteine desulfurase activity
FPL13_RS03010	COG0301	tRNA thio-modification
FPL13_RS03030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FPL13_RS03040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FPL13_RS03045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPL13_RS03045	COG0425	Belongs to the sulfur carrier protein TusA family
FPL13_RS03050	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPL13_RS03065	COG1937	Protein conserved in bacteria
FPL13_RS03075	COG0583	DNA-binding transcription factor activity
FPL13_RS03085	COG0564	pseudouridine synthase activity
FPL13_RS03090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FPL13_RS03095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FPL13_RS03100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FPL13_RS03105	COG2824	Alkylphosphonate utilization operon protein PhnA
FPL13_RS03125	COG0038	chloride channel
FPL13_RS03130	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FPL13_RS03135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FPL13_RS03150	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FPL13_RS03155	COG1388	LysM domain
FPL13_RS03155	COG1705	Flagellar rod assembly protein muramidase FlgJ
FPL13_RS03165	COG1132	(ABC) transporter
FPL13_RS03170	COG0488	(ABC) transporter
FPL13_RS03190	COG0556	nucleotide-excision repair
FPL13_RS03205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FPL13_RS03215	COG0647	UMP catabolic process
FPL13_RS03235	COG1660	Displays ATPase and GTPase activities
FPL13_RS03240	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FPL13_RS03245	COG1481	regulation of sporulation
FPL13_RS03250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FPL13_RS03260	COG0540	Belongs to the ATCase OTCase family
FPL13_RS03265	COG0505	Belongs to the CarA family
FPL13_RS03270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FPL13_RS03275	COG1940	carbohydrate kinase activity
FPL13_RS03295	COG0745	RESPONSE REGULATOR receiver
FPL13_RS03300	COG5002	protein histidine kinase activity
FPL13_RS03310	COG4187	Peptidase family M20/M25/M40
FPL13_RS03320	COG0268	Binds directly to 16S ribosomal RNA
FPL13_RS03325	COG1072	(Pantothenic acid kinase))
FPL13_RS03330	COG2813	Specifically methylates the guanine in position
FPL13_RS03340	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FPL13_RS03345	COG0295	cytidine deaminase activity
FPL13_RS03350	COG1744	ABC transporter substrate-binding protein PnrA-like
FPL13_RS03355	COG3845	ABC transporter
FPL13_RS03360	COG4603	Belongs to the binding-protein-dependent transport system permease family
FPL13_RS03365	COG1079	Belongs to the binding-protein-dependent transport system permease family
FPL13_RS03370	COG1272	protein, Hemolysin III
FPL13_RS03380	COG3022	response to hydroperoxide
FPL13_RS03385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FPL13_RS03390	COG1846	Transcriptional regulator
FPL13_RS03400	COG0436	Aminotransferase
FPL13_RS03410	COG0017	Asparaginyl-tRNA synthetase
FPL13_RS03415	COG2814	Major facilitator Superfamily
FPL13_RS03460	COG1309	transcriptional regulator
FPL13_RS03465	COG2131	deaminase
FPL13_RS03475	COG0737	Belongs to the 5'-nucleotidase family
FPL13_RS03480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FPL13_RS03485	COG0187	DNA topoisomerase II activity
FPL13_RS03505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FPL13_RS03510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FPL13_RS03530	COG0539	negative regulation of cytoplasmic translation
FPL13_RS03545	COG0039	L-malate dehydrogenase activity
FPL13_RS03550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FPL13_RS03555	COG3764	Sortase (surface protein transpeptidase)
FPL13_RS03570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPL13_RS03575	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FPL13_RS03580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FPL13_RS03585	COG3711	transcriptional antiterminator
FPL13_RS03590	COG0110	maltose O-acetyltransferase activity
FPL13_RS03595	COG0758	DNA mediated transformation
FPL13_RS03600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FPL13_RS03605	COG0135	phosphoribosylanthranilate isomerase activity
FPL13_RS03610	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FPL13_RS03630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FPL13_RS03635	COG0022	dehydrogenase e1 component
FPL13_RS03640	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPL13_RS03645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPL13_RS03650	COG0095	Lipoate-protein ligase
FPL13_RS03655	COG4974	Belongs to the 'phage' integrase family
FPL13_RS03660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FPL13_RS03670	COG2188	Transcriptional regulator
FPL13_RS03695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FPL13_RS03705	COG2890	protein-(glutamine-N5) methyltransferase activity
FPL13_RS03710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FPL13_RS03715	COG1435	thymidine kinase activity
FPL13_RS03720	COG1942	4-Oxalocrotonate Tautomerase
FPL13_RS03725	COG0534	Mate efflux family protein
FPL13_RS03730	COG2233	PERMEase
FPL13_RS03735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FPL13_RS03765	COG0745	RESPONSE REGULATOR receiver
FPL13_RS03770	COG2205	protein histidine kinase activity
FPL13_RS03790	COG0431	NADPH-dependent FMN reductase
FPL13_RS03790	COG3976	FMN-binding domain protein
FPL13_RS03790	COG1053	succinate dehydrogenase
FPL13_RS03795	COG4555	ABC transporter
FPL13_RS03810	COG2972	Histidine kinase
FPL13_RS03815	COG2197	response regulator
FPL13_RS03820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPL13_RS03820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPL13_RS03825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPL13_RS03830	COG0785	Cytochrome C biogenesis protein
FPL13_RS03835	COG1114	Component of the transport system for branched-chain amino acids
FPL13_RS03840	COG2151	metal-sulfur cluster biosynthetic enzyme
FPL13_RS03845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FPL13_RS03855	COG1970	mechanosensitive ion channel activity
FPL13_RS03860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FPL13_RS03885	COG1518	maintenance of DNA repeat elements
FPL13_RS03895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL13_RS03900	COG1132	(ABC) transporter
FPL13_RS03905	COG1132	(ABC) transporter
FPL13_RS03910	COG2315	Protein conserved in bacteria
FPL13_RS03915	COG3142	Participates in the control of copper homeostasis
FPL13_RS03930	COG1827	regulation of RNA biosynthetic process
FPL13_RS03935	COG1837	Belongs to the UPF0109 family
FPL13_RS03940	COG0228	four-way junction DNA binding
FPL13_RS03945	COG1523	belongs to the glycosyl hydrolase 13 family
FPL13_RS03960	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FPL13_RS03965	COG4708	membrane
FPL13_RS03970	COG2246	polysaccharide biosynthetic process
FPL13_RS03980	COG1846	Transcriptional regulator
FPL13_RS03990	COG0024	Methionine aminopeptidase
FPL13_RS03995	COG4109	DRTGG domain
FPL13_RS04005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FPL13_RS04010	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FPL13_RS04015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FPL13_RS04020	COG1051	belongs to the nudix hydrolase family
FPL13_RS04025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FPL13_RS04055	COG1555	photosystem II stabilization
FPL13_RS04065	COG0557	exoribonuclease II activity
FPL13_RS04075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FPL13_RS04080	COG2814	Major facilitator Superfamily
FPL13_RS04085	COG1063	alcohol dehydrogenase
FPL13_RS04095	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FPL13_RS04120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FPL13_RS04125	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FPL13_RS04130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FPL13_RS04135	COG1132	(ABC) transporter
FPL13_RS04140	COG1132	(ABC) transporter
FPL13_RS04155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL13_RS04160	COG0686	Belongs to the AlaDH PNT family
FPL13_RS04165	COG1702	phosphate starvation-inducible protein PhoH
FPL13_RS04170	COG4479	Belongs to the UPF0346 family
FPL13_RS04185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FPL13_RS04195	COG0284	orotidine-5'-phosphate decarboxylase activity
FPL13_RS04200	COG0167	dihydroorotate dehydrogenase activity
FPL13_RS04205	COG0543	2 iron, 2 sulfur cluster binding
FPL13_RS04210	COG0583	DNA-binding transcription factor activity
FPL13_RS04230	COG0583	DNA-binding transcription factor activity
FPL13_RS04235	COG2814	Major facilitator Superfamily
FPL13_RS04240	COG3328	transposase activity
FPL13_RS04250	COG0656	L-ascorbic acid biosynthetic process
FPL13_RS04260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL13_RS04260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL13_RS04270	COG0083	homoserine kinase activity
FPL13_RS04280	COG0726	polysaccharide deacetylase
FPL13_RS04290	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FPL13_RS04300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FPL13_RS04300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FPL13_RS04305	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FPL13_RS04310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FPL13_RS04315	COG1609	Transcriptional regulator
FPL13_RS04320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FPL13_RS04320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FPL13_RS04335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FPL13_RS04340	COG1956	GAF domain-containing protein
FPL13_RS04355	COG0803	Belongs to the bacterial solute-binding protein 9 family
FPL13_RS04355	COG3443	Belongs to the bacterial solute-binding protein 9 family
FPL13_RS04365	COG0336	Belongs to the RNA methyltransferase TrmD family
FPL13_RS04370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FPL13_RS04405	COG5504	Zn-dependent protease
FPL13_RS04410	COG0222	ribosome binding
FPL13_RS04415	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FPL13_RS04420	COG2207	Transcriptional regulator
FPL13_RS04420	COG3708	Transcriptional regulator
FPL13_RS04435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPL13_RS04455	COG0281	malic enzyme
FPL13_RS04465	COG0583	DNA-binding transcription factor activity
FPL13_RS04475	COG1247	-acetyltransferase
FPL13_RS04480	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FPL13_RS04490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FPL13_RS04495	COG4684	Psort location CytoplasmicMembrane, score
FPL13_RS04500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPL13_RS04515	COG0280	phosphate acetyltransferase
FPL13_RS04520	COG0564	pseudouridine synthase activity
FPL13_RS04540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FPL13_RS04545	COG1104	cysteine desulfurase activity
FPL13_RS04560	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FPL13_RS04565	COG2003	Belongs to the UPF0758 family
FPL13_RS04570	COG0704	Plays a role in the regulation of phosphate uptake
FPL13_RS04575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FPL13_RS04580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FPL13_RS04585	COG0581	inorganic phosphate transmembrane transporter activity
FPL13_RS04590	COG0573	inorganic phosphate transmembrane transporter activity
FPL13_RS04600	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FPL13_RS04600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FPL13_RS04605	COG0483	inositol monophosphate 1-phosphatase activity
FPL13_RS04610	COG4476	Belongs to the UPF0223 family
FPL13_RS04615	COG1393	Belongs to the ArsC family
FPL13_RS04620	COG0196	riboflavin kinase activity
FPL13_RS04625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FPL13_RS04645	COG1132	(ABC) transporter
FPL13_RS04650	COG2375	cellular response to nickel ion
FPL13_RS04650	COG1132	(ABC) transporter
FPL13_RS04655	COG2378	regulation of single-species biofilm formation
FPL13_RS04665	COG0210	DNA helicase
FPL13_RS04670	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FPL13_RS04680	COG1126	abc transporter atp-binding protein
FPL13_RS04685	COG0765	amino acid transport
FPL13_RS04695	COG0469	pyruvate kinase activity
FPL13_RS04700	COG0205	6-phosphofructokinase activity
FPL13_RS04710	COG1725	Transcriptional regulator
FPL13_RS04715	COG1131	(ABC) transporter
FPL13_RS04725	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FPL13_RS04725	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FPL13_RS04740	COG0300	oxidoreductase activity
FPL13_RS04760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FPL13_RS04765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FPL13_RS04775	COG0577	efflux transmembrane transporter activity
FPL13_RS04780	COG1136	(ABC) transporter
FPL13_RS04790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPL13_RS04795	COG1268	BioY protein
FPL13_RS04810	COG0072	phenylalanine-tRNA ligase activity
FPL13_RS04810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPL13_RS04825	COG0488	(ABC) transporter
FPL13_RS04830	COG0617	tRNA 3'-terminal CCA addition
FPL13_RS04835	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FPL13_RS04840	COG1307	EDD domain protein, DegV family
FPL13_RS04850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPL13_RS04850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FPL13_RS04850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FPL13_RS04855	COG1105	Belongs to the carbohydrate kinase PfkB family
FPL13_RS04860	COG1349	DNA-binding transcription factor activity
FPL13_RS04870	COG0492	ferredoxin-NADP+ reductase activity
FPL13_RS04875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPL13_RS04895	COG1396	sequence-specific DNA binding
FPL13_RS04905	COG2723	6-phospho-beta-galactosidase activity
FPL13_RS04920	COG3711	transcriptional antiterminator
FPL13_RS04925	COG3684	Belongs to the aldolase LacD family
FPL13_RS04930	COG1105	Belongs to the carbohydrate kinase PfkB family
FPL13_RS04935	COG0698	ribose 5-phosphate isomerase
FPL13_RS04940	COG0698	ribose 5-phosphate isomerase
FPL13_RS04945	COG1349	DNA-binding transcription factor activity
FPL13_RS04950	COG3843	relaxase mobilization nuclease domain protein
FPL13_RS04965	COG0542	response to heat
FPL13_RS04975	COG0542	response to heat
FPL13_RS04980	COG1396	sequence-specific DNA binding
FPL13_RS05105	COG0270	DNA (cytosine-5-)-methyltransferase activity
FPL13_RS05130	COG3340	Belongs to the peptidase S51 family
FPL13_RS05170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FPL13_RS05170	COG0551	DNA topoisomerase type I activity
FPL13_RS05235	COG1484	DNA-dependent DNA replication
FPL13_RS05250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FPL13_RS05260	COG0077	Prephenate dehydratase
FPL13_RS05265	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FPL13_RS05270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FPL13_RS05280	COG3679	Belongs to the UPF0342 family
FPL13_RS05285	COG0287	Prephenate dehydrogenase
FPL13_RS05295	COG0730	response to heat
FPL13_RS05300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FPL13_RS05305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FPL13_RS05310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FPL13_RS05315	COG0710	3-dehydroquinate dehydratase activity
FPL13_RS05320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FPL13_RS05325	COG1368	sulfuric ester hydrolase activity
FPL13_RS05335	COG0813	purine-nucleoside phosphorylase activity
FPL13_RS05350	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FPL13_RS05395	COG1091	dTDP-4-dehydrorhamnose reductase activity
FPL13_RS05400	COG0463	Glycosyl transferase, family 2
FPL13_RS05415	COG1216	Glycosyl transferase, family 2
FPL13_RS05415	COG1442	glycosyl transferase family 8
FPL13_RS05435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FPL13_RS05445	COG1088	dTDP-glucose 4,6-dehydratase activity
FPL13_RS05455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FPL13_RS05470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPL13_RS05475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FPL13_RS05490	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FPL13_RS05495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FPL13_RS05500	COG1346	cytolysis
FPL13_RS05545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FPL13_RS05565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FPL13_RS05570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FPL13_RS05575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FPL13_RS05580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FPL13_RS05585	COG0356	it plays a direct role in the translocation of protons across the membrane
FPL13_RS05595	COG0058	SHG alpha-glucan phosphorylase activity
FPL13_RS05600	COG0297	glycogen (starch) synthase activity
FPL13_RS05605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FPL13_RS05610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FPL13_RS05615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FPL13_RS05620	COG1074	ATP-dependent DNA helicase activity
FPL13_RS05630	COG1668	transmembrane transport
FPL13_RS05635	COG4152	abc transporter atp-binding protein
FPL13_RS05640	COG4443	Transcriptional Coactivator p15 (PC4)
FPL13_RS05650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FPL13_RS05665	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FPL13_RS05670	COG3527	Alpha-acetolactate decarboxylase
FPL13_RS05675	COG0028	Belongs to the TPP enzyme family
FPL13_RS05685	COG0628	permease
FPL13_RS05690	COG3850	Histidine kinase
FPL13_RS05690	COG5002	protein histidine kinase activity
FPL13_RS05695	COG0745	RESPONSE REGULATOR receiver
FPL13_RS05700	COG2706	6-phosphogluconolactonase activity
FPL13_RS05705	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FPL13_RS05710	COG0187	DNA topoisomerase II activity
FPL13_RS05725	COG0772	Belongs to the SEDS family
FPL13_RS05735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FPL13_RS05735	COG1199	ATP-dependent helicase activity
FPL13_RS05745	COG2177	Part of the ABC transporter FtsEX involved in
FPL13_RS05750	COG2884	Cell division ATP-binding protein ftsE
FPL13_RS05760	COG0561	phosphatase activity
FPL13_RS05795	COG1078	dGTPase activity
FPL13_RS05805	COG2348	transferase activity, transferring amino-acyl groups
FPL13_RS05820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FPL13_RS05830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPL13_RS05835	COG4122	O-methyltransferase activity
FPL13_RS05850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL13_RS05860	COG1447	Phosphotransferase system cellobiose-specific component IIA
FPL13_RS05865	COG3711	transcriptional antiterminator
FPL13_RS05865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPL13_RS05875	COG4095	Psort location CytoplasmicMembrane, score
FPL13_RS05880	COG2723	6-phospho-beta-galactosidase activity
FPL13_RS05905	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FPL13_RS05910	COG1438	arginine binding
FPL13_RS05915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPL13_RS05920	COG1288	antiporter activity
FPL13_RS05925	COG0549	Belongs to the carbamate kinase family
FPL13_RS05930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FPL13_RS05955	COG2274	protein secretion by the type I secretion system
FPL13_RS05960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FPL13_RS05965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FPL13_RS06000	COG2996	Protein conserved in bacteria
FPL13_RS06005	COG0233	cytoplasmic translational termination
FPL13_RS06010	COG0528	UMP kinase activity
FPL13_RS06015	COG0081	regulation of translation
FPL13_RS06030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FPL13_RS06035	COG1674	ftsk spoiiie
FPL13_RS06035	COG0697	spore germination
FPL13_RS06040	COG1983	PspC domain protein
FPL13_RS06060	COG0488	(ABC) transporter
FPL13_RS06065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FPL13_RS06080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FPL13_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
FPL13_RS06115	COG0456	acetyltransferase
FPL13_RS06120	COG0531	amino acid
FPL13_RS06125	COG0577	efflux transmembrane transporter activity
FPL13_RS06130	COG1136	(ABC) transporter
FPL13_RS06155	COG0577	efflux transmembrane transporter activity
FPL13_RS06160	COG1136	(ABC) transporter
FPL13_RS06170	COG0642	Histidine kinase
FPL13_RS06175	COG0745	RESPONSE REGULATOR receiver
FPL13_RS06185	COG2723	6-phospho-beta-galactosidase activity
FPL13_RS06200	COG1940	carbohydrate kinase activity
FPL13_RS06205	COG2188	Transcriptional regulator
FPL13_RS06220	COG0395	ABC-type sugar transport system, permease component
FPL13_RS06225	COG1175	transmembrane transport
FPL13_RS06230	COG1653	transport
FPL13_RS06235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPL13_RS06235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPL13_RS06260	COG0640	Transcriptional regulator
FPL13_RS06290	COG3843	relaxase mobilization nuclease domain protein
FPL13_RS06360	COG1388	LysM domain
FPL13_RS06360	COG3942	CHAP domain
FPL13_RS06410	COG0708	Exodeoxyribonuclease III
FPL13_RS06415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FPL13_RS06420	COG1393	Belongs to the ArsC family
FPL13_RS06425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FPL13_RS06435	COG4467	Involved in initiation control of chromosome replication
FPL13_RS06440	COG0470	DNA polymerase III
FPL13_RS06445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FPL13_RS06450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL13_RS06455	COG0517	IMP dehydrogenase activity
FPL13_RS06470	COG4177	L-phenylalanine transmembrane transporter activity
FPL13_RS06490	COG0740	serine-type endopeptidase activity
FPL13_RS06495	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FPL13_RS06500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FPL13_RS06510	COG0626	cystathionine gamma-synthase activity
FPL13_RS06515	COG2244	polysaccharide biosynthetic process
FPL13_RS06520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FPL13_RS06545	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FPL13_RS06555	COG0366	Alpha amylase catalytic
FPL13_RS06560	COG1263	PTS System
FPL13_RS06560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL13_RS06565	COG2188	Transcriptional regulator
FPL13_RS06570	COG1253	flavin adenine dinucleotide binding
FPL13_RS06590	COG1846	Transcriptional regulator
FPL13_RS06595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FPL13_RS06600	COG3599	regulation of cell shape
FPL13_RS06615	COG1799	cell septum assembly
FPL13_RS06620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FPL13_RS06625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FPL13_RS06635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FPL13_RS06640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FPL13_RS06645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FPL13_RS06655	COG1217	gtp-binding protein TYPA
FPL13_RS06660	COG1187	pseudouridine synthase activity
FPL13_RS06700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FPL13_RS06705	COG4470	Protein conserved in bacteria
FPL13_RS06710	COG3480	Lon protease (S16) C-terminal proteolytic domain
FPL13_RS06715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FPL13_RS06720	COG0742	ribosomal rna small subunit methyltransferase
FPL13_RS06735	COG1040	competence protein
FPL13_RS06740	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FPL13_RS06745	COG1739	Uncharacterized protein family UPF0029
FPL13_RS06755	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FPL13_RS06760	COG1518	maintenance of DNA repeat elements
FPL13_RS06790	COG0525	valine-tRNA ligase activity
FPL13_RS06800	COG0519	Catalyzes the synthesis of GMP from XMP
FPL13_RS06830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FPL13_RS06840	COG2137	regulation of response to DNA damage stimulus
FPL13_RS06845	COG3557	Belongs to the UPF0374 family
FPL13_RS06855	COG1185	polyribonucleotide nucleotidyltransferase activity
FPL13_RS06870	COG4585	Histidine kinase
FPL13_RS06880	COG2815	serine threonine protein kinase
FPL13_RS06880	COG0515	serine threonine protein kinase
FPL13_RS06885	COG0631	protein serine/threonine phosphatase activity
FPL13_RS06890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FPL13_RS06890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPL13_RS06895	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FPL13_RS06900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FPL13_RS06905	COG1758	RNA polymerase activity
FPL13_RS06910	COG0194	GDP metabolic process
FPL13_RS06915	COG1418	mRNA catabolic process
FPL13_RS06925	COG3634	alkyl hydroperoxide reductase activity
FPL13_RS06930	COG0450	alkyl hydroperoxide reductase
FPL13_RS06950	COG3599	regulation of cell shape
FPL13_RS06960	COG3331	DNA recombination
FPL13_RS06965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPL13_RS06970	COG3579	cysteine-type endopeptidase activity
FPL13_RS06980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FPL13_RS06985	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FPL13_RS06990	COG1113	amino acid transport
FPL13_RS06995	COG0492	ferredoxin-NADP+ reductase activity
FPL13_RS07005	COG1126	abc transporter atp-binding protein
FPL13_RS07025	COG1686	Belongs to the peptidase S11 family
FPL13_RS07035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPL13_RS07040	COG0719	Fe-S assembly protein
FPL13_RS07050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPL13_RS07055	COG4862	establishment of competence for transformation
FPL13_RS07065	COG1968	undecaprenyl-diphosphatase activity
FPL13_RS07075	COG0765	amino acid transport
FPL13_RS07080	COG1126	abc transporter atp-binding protein
FPL13_RS07095	COG2197	response regulator
FPL13_RS07110	COG1131	(ABC) transporter
FPL13_RS07115	COG1461	Dihydroxyacetone kinase
FPL13_RS07125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FPL13_RS07150	COG0191	fructose-bisphosphate aldolase activity
FPL13_RS07170	COG0504	CTP synthase activity
FPL13_RS07180	COG4166	transmembrane transport
FPL13_RS07185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPL13_RS07190	COG0768	penicillin binding
FPL13_RS07200	COG0275	rRNA processing
FPL13_RS07220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FPL13_RS07235	COG0751	glycine-tRNA ligase activity
FPL13_RS07240	COG0752	glycyl-tRNA synthetase alpha subunit
FPL13_RS07255	COG1283	sodium-dependent phosphate transmembrane transporter activity
FPL13_RS07260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FPL13_RS07275	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FPL13_RS07280	COG0195	Participates in both transcription termination and antitermination
FPL13_RS07285	COG0779	Required for maturation of 30S ribosomal subunits
FPL13_RS07295	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FPL13_RS07300	COG0510	thiamine kinase activity
FPL13_RS07310	COG1131	(ABC) transporter
FPL13_RS07315	COG0537	adenosine 5'-monophosphoramidase activity
FPL13_RS07325	COG1316	TRANSCRIPTIONal
FPL13_RS07335	COG0802	atpase or kinase
FPL13_RS07340	COG2252	PERMEase
FPL13_RS07350	COG0561	phosphatase activity
FPL13_RS07360	COG3715	PTS system
FPL13_RS07365	COG3716	PTS system mannose fructose sorbose family IID component
FPL13_RS07380	COG0586	Pfam SNARE associated Golgi protein
FPL13_RS07385	COG0825	malonyl-CoA metabolic process
FPL13_RS07390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FPL13_RS07395	COG0439	Biotin carboxylase
FPL13_RS07400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FPL13_RS07410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FPL13_RS07420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FPL13_RS07425	COG2070	2-Nitropropane dioxygenase
FPL13_RS07435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPL13_RS07445	COG1024	Enoyl-CoA hydratase
FPL13_RS07450	COG0527	aspartate kinase activity
FPL13_RS07500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FPL13_RS07505	COG0006	proline dipeptidase activity
FPL13_RS07515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FPL13_RS07530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FPL13_RS07535	COG0629	single-stranded DNA binding
FPL13_RS07560	COG0588	phosphoglycerate mutase activity
FPL13_RS07575	COG2723	6-phospho-beta-galactosidase activity
FPL13_RS07585	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FPL13_RS07610	COG2813	Specifically methylates the guanine in position
FPL13_RS07625	COG0366	Alpha amylase catalytic
FPL13_RS07640	COG5002	protein histidine kinase activity
FPL13_RS07645	COG0745	RESPONSE REGULATOR receiver
FPL13_RS07650	COG2723	6-phospho-beta-galactosidase activity
FPL13_RS07660	COG0028	Belongs to the TPP enzyme family
FPL13_RS07665	COG1876	peptidase activity
FPL13_RS07685	COG0561	phosphatase activity
FPL13_RS07695	COG0346	lactoylglutathione lyase activity
FPL13_RS07720	COG1263	PTS System
FPL13_RS07720	COG2190	(PTS) system
FPL13_RS07720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL13_RS07725	COG1447	Phosphotransferase system cellobiose-specific component IIA
FPL13_RS07730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL13_RS07740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL13_RS07755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPL13_RS07755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPL13_RS07760	COG0167	dihydroorotate dehydrogenase activity
FPL13_RS07765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FPL13_RS07775	COG0668	transmembrane transport
FPL13_RS07780	COG3118	belongs to the thioredoxin family
FPL13_RS07790	COG1193	negative regulation of DNA recombination
FPL13_RS07810	COG0681	Belongs to the peptidase S26 family
FPL13_RS07815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FPL13_RS07820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FPL13_RS07825	COG1882	Formate acetyltransferase
FPL13_RS07840	COG3425	synthase
FPL13_RS07850	COG1304	FMN binding
FPL13_RS07870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPL13_RS07885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FPL13_RS07890	COG2936	dipeptidyl-peptidase activity
FPL13_RS07895	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FPL13_RS07900	COG0584	glycerophosphoryl diester phosphodiesterase
FPL13_RS07915	COG2081	HI0933 family
FPL13_RS07920	COG0789	Transcriptional regulator
FPL13_RS07975	COG0433	COG0433 Predicted ATPase
FPL13_RS08015	COG1794	racemase activity, acting on amino acids and derivatives
FPL13_RS08035	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPL13_RS08050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL13_RS08060	COG1266	CAAX protease self-immunity
FPL13_RS08190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FPL13_RS08195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPL13_RS08200	COG0564	pseudouridine synthase activity
FPL13_RS08220	COG3443	Belongs to the bacterial solute-binding protein 9 family
FPL13_RS08220	COG0803	Belongs to the bacterial solute-binding protein 9 family
FPL13_RS08225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FPL13_RS08230	COG1121	(ABC) transporter
FPL13_RS08235	COG1846	Transcriptional regulator
FPL13_RS08255	COG1914	H( )-stimulated, divalent metal cation uptake system
FPL13_RS08280	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FPL13_RS08285	COG1309	transcriptional regulator
FPL13_RS08300	COG1394	ATPase activity, coupled to movement of substances
FPL13_RS08305	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FPL13_RS08310	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FPL13_RS08320	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
FPL13_RS08325	COG1527	subunit (C
FPL13_RS08335	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FPL13_RS08340	COG1269	ATP hydrolysis coupled proton transport
FPL13_RS08360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPL13_RS08385	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FPL13_RS08395	COG1454	alcohol dehydrogenase
FPL13_RS08400	COG1012	belongs to the aldehyde dehydrogenase family
FPL13_RS08400	COG1454	alcohol dehydrogenase
FPL13_RS08410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FPL13_RS08565	COG0582	viral genome integration into host DNA
FPL13_RS08620	COG1484	DNA-dependent DNA replication
FPL13_RS08630	COG0305	Participates in initiation and elongation during chromosome replication
FPL13_RS08665	COG1396	sequence-specific DNA binding
FPL13_RS08695	COG2255	four-way junction helicase activity
FPL13_RS08705	COG3684	Belongs to the aldolase LacD family
FPL13_RS08710	COG2222	sugar isomerase
FPL13_RS08720	COG3716	PTS system mannose fructose sorbose family IID component
FPL13_RS08730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL13_RS08755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FPL13_RS08770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FPL13_RS08775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FPL13_RS08785	COG0151	Belongs to the GarS family
FPL13_RS08815	COG3942	CHAP domain
FPL13_RS08830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FPL13_RS08835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FPL13_RS08840	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FPL13_RS08845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FPL13_RS08850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FPL13_RS08855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPL13_RS08870	COG0436	Aminotransferase
FPL13_RS08875	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FPL13_RS08880	COG3942	CHAP domain
FPL13_RS08890	COG1792	Involved in formation and maintenance of cell shape
FPL13_RS09010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FPL13_RS09015	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FPL13_RS09035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FPL13_RS09040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FPL13_RS09045	COG0193	aminoacyl-tRNA hydrolase activity
FPL13_RS09050	COG0012	GTP binding
FPL13_RS09065	COG0592	DNA-directed DNA polymerase activity
FPL13_RS09075	COG1475	DNA binding
FPL13_RS09080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPL13_RS09085	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FPL13_RS09130	COG0488	(ABC) transporter
FPL13_RS09135	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPL13_RS09140	COG0149	triose-phosphate isomerase activity
FPL13_RS09145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FPL13_RS09150	COG0180	Tryptophanyl-tRNA synthetase
FPL13_RS09155	COG0516	GMP reductase activity
FPL13_RS09155	COG0517	IMP dehydrogenase activity
FPL13_RS09160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FPL13_RS09170	COG0612	Peptidase, M16
FPL13_RS09175	COG0612	Peptidase, M16
FPL13_RS09185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FPL13_RS09190	COG1122	ATPase activity
FPL13_RS09195	COG1122	ATPase activity
FPL13_RS09200	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FPL13_RS09215	COG1760	l-serine dehydratase
FPL13_RS09220	COG1760	l-serine dehydratase
FPL13_RS09235	COG0445	tRNA wobble uridine modification
FPL13_RS09250	COG0305	Participates in initiation and elongation during chromosome replication
FPL13_RS09260	COG1011	Hydrolase
FPL13_RS09285	COG0561	phosphatase activity
FPL13_RS09350	COG1696	Membrane protein involved in D-alanine export
FPL13_RS09355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPL13_RS09360	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FPL13_RS09370	COG0561	phosphatase activity
FPL13_RS09375	COG2094	Belongs to the DNA glycosylase MPG family
FPL13_RS09380	COG2807	transmembrane transport
FPL13_RS09390	COG1230	cation diffusion facilitator family transporter
FPL13_RS09395	COG3328	transposase activity
FPL13_RS09435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FPL13_RS09445	COG0124	histidyl-tRNA synthetase
FPL13_RS09460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL13_RS09465	COG1523	belongs to the glycosyl hydrolase 13 family
FPL13_RS09470	COG1609	Transcriptional regulator
FPL13_RS09475	COG5521	maltodextrose utilization protein MalA
FPL13_RS09480	COG3833	ABC-type maltose transport systems, permease component
FPL13_RS09485	COG1175	transmembrane transport
FPL13_RS09490	COG2182	Extracellular solute-binding protein
FPL13_RS09495	COG1640	4-alpha-glucanotransferase
FPL13_RS09500	COG0058	SHG alpha-glucan phosphorylase activity
FPL13_RS09510	COG1780	Probably involved in ribonucleotide reductase function
FPL13_RS09515	COG0018	arginyl-trna synthetase
FPL13_RS09520	COG1438	arginine binding
FPL13_RS09525	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FPL13_RS09540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FPL13_RS09545	COG0632	four-way junction helicase activity
FPL13_RS09550	COG0519	Catalyzes the synthesis of GMP from XMP
FPL13_RS09570	COG1058	Belongs to the CinA family
FPL13_RS09570	COG1546	Belongs to the CinA family
FPL13_RS09575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FPL13_RS09580	COG1393	Belongs to the ArsC family
FPL13_RS09595	COG4472	Bacterial protein of unknown function (DUF965)
FPL13_RS09600	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FPL13_RS09605	COG3906	Belongs to the UPF0473 family
FPL13_RS09620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol