locus-tag	class	description
LPB220_RS00010	COG0592	DNA-directed DNA polymerase activity
LPB220_RS00025	COG0012	GTP binding
LPB220_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LPB220_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LPB220_RS00055	COG0037	tRNA processing
LPB220_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LPB220_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LPB220_RS00190	COG1792	Involved in formation and maintenance of cell shape
LPB220_RS00200	COG3942	CHAP domain
LPB220_RS00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPB220_RS00220	COG0436	Aminotransferase
LPB220_RS00225	COG1381	Involved in DNA repair and RecF pathway recombination
LPB220_RS00235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPB220_RS00240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LPB220_RS00245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPB220_RS00250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LPB220_RS00260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LPB220_RS00275	COG3942	CHAP domain
LPB220_RS00280	COG0151	Belongs to the GarS family
LPB220_RS00285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LPB220_RS00305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LPB220_RS00315	COG2188	Transcriptional regulator
LPB220_RS00325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LPB220_RS00330	COG3715	PTS system
LPB220_RS00335	COG3716	PTS system mannose fructose sorbose family IID component
LPB220_RS00345	COG2222	sugar isomerase
LPB220_RS00370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LPB220_RS00380	COG2755	lipolytic protein G-D-S-L family
LPB220_RS00380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LPB220_RS00385	COG1454	alcohol dehydrogenase
LPB220_RS00385	COG1012	belongs to the aldehyde dehydrogenase family
LPB220_RS00405	COG1063	alcohol dehydrogenase
LPB220_RS00420	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LPB220_RS00425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPB220_RS00430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LPB220_RS00440	COG0673	inositol 2-dehydrogenase activity
LPB220_RS00450	COG1737	Transcriptional regulator
LPB220_RS00465	COG1269	ATP hydrolysis coupled proton transport
LPB220_RS00470	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPB220_RS00480	COG1527	subunit (C
LPB220_RS00485	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
LPB220_RS00495	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
LPB220_RS00500	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
LPB220_RS00505	COG1394	ATPase activity, coupled to movement of substances
LPB220_RS00510	COG3409	Peptidoglycan-binding domain 1 protein
LPB220_RS00510	COG5632	N-Acetylmuramoyl-L-alanine amidase
LPB220_RS00515	COG2807	transmembrane transport
LPB220_RS00530	COG0640	Transcriptional regulator
LPB220_RS00550	COG3457	Alanine racemase
LPB220_RS00565	COG4974	Belongs to the 'phage' integrase family
LPB220_RS00575	COG1705	Flagellar rod assembly protein muramidase FlgJ
LPB220_RS00575	COG3942	CHAP domain
LPB220_RS00590	COG0433	COG0433 Predicted ATPase
LPB220_RS00625	COG1674	ftsk spoiiie
LPB220_RS00645	COG3620	sequence-specific DNA binding
LPB220_RS00670	COG3620	sequence-specific DNA binding
LPB220_RS00680	COG0789	Transcriptional regulator
LPB220_RS00690	COG2184	nucleotidyltransferase activity
LPB220_RS00700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LPB220_RS00725	COG2151	metal-sulfur cluster biosynthetic enzyme
LPB220_RS00740	COG0534	Mate efflux family protein
LPB220_RS00750	COG1846	Transcriptional regulator
LPB220_RS00755	COG3759	membrane
LPB220_RS00760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LPB220_RS00765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LPB220_RS00795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LPB220_RS00795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LPB220_RS00800	COG1832	CoA-binding protein
LPB220_RS00840	COG0088	Forms part of the polypeptide exit tunnel
LPB220_RS00850	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LPB220_RS00855	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LPB220_RS00875	COG0255	Belongs to the universal ribosomal protein uL29 family
LPB220_RS00880	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LPB220_RS00885	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LPB220_RS00890	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LPB220_RS00895	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LPB220_RS00900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LPB220_RS00905	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LPB220_RS00920	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LPB220_RS00925	COG1841	ribosomal large subunit assembly
LPB220_RS00930	COG0200	Binds to the 23S rRNA
LPB220_RS00935	COG0201	protein transport
LPB220_RS00945	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LPB220_RS00950	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LPB220_RS00955	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LPB220_RS00960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LPB220_RS00965	COG0202	RNA polymerase activity
LPB220_RS00970	COG0203	ribosomal protein L17
LPB220_RS01060	COG1846	Transcriptional regulator
LPB220_RS01065	COG1121	(ABC) transporter
LPB220_RS01070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LPB220_RS01075	COG0803	Belongs to the bacterial solute-binding protein 9 family
LPB220_RS01075	COG3443	Belongs to the bacterial solute-binding protein 9 family
LPB220_RS01090	COG3537	Alpha-1,2-mannosidase
LPB220_RS01100	COG0383	alpha-mannosidase activity
LPB220_RS01115	COG4209	transmembrane transport
LPB220_RS01120	COG0395	ABC-type sugar transport system, permease component
LPB220_RS01125	COG1653	transport
LPB220_RS01135	COG2972	Histidine kinase
LPB220_RS01140	COG2207	Transcriptional regulator
LPB220_RS01140	COG4753	response regulator
LPB220_RS01145	COG1309	transcriptional regulator
LPB220_RS01150	COG2249	NAD(P)H dehydrogenase (quinone) activity
LPB220_RS01155	COG0500	methyltransferase
LPB220_RS01165	COG1733	regulation of RNA biosynthetic process
LPB220_RS01180	COG3279	Response regulator of the LytR AlgR family
LPB220_RS01195	COG4499	WXG100 protein secretion system (Wss), protein YukC
LPB220_RS01195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LPB220_RS01200	COG0085	RNA polymerase activity
LPB220_RS01205	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPB220_RS01215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LPB220_RS01220	COG1459	type II secretion system
LPB220_RS01225	COG4537	Required for transformation and DNA binding
LPB220_RS01250	COG0827	DNA restriction-modification system
LPB220_RS01255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LPB220_RS01260	COG1266	CAAX protease self-immunity
LPB220_RS01265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LPB220_RS01270	COG0285	dihydrofolate synthase activity
LPB220_RS01275	COG0302	gtp cyclohydrolase
LPB220_RS01280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LPB220_RS01280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LPB220_RS01285	COG4868	Belongs to the UPF0371 family
LPB220_RS01290	COG1363	Peptidase, m42
LPB220_RS01300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB220_RS01305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPB220_RS01320	COG4585	Histidine kinase
LPB220_RS01325	COG2197	response regulator
LPB220_RS01350	COG3716	PTS system mannose fructose sorbose family IID component
LPB220_RS01360	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LPB220_RS01410	COG0656	L-ascorbic acid biosynthetic process
LPB220_RS01445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LPB220_RS01460	COG1051	belongs to the nudix hydrolase family
LPB220_RS01470	COG2264	protein methyltransferase activity
LPB220_RS01475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LPB220_RS01520	COG3590	peptidase
LPB220_RS01530	COG1686	Belongs to the peptidase S11 family
LPB220_RS01535	COG4166	transmembrane transport
LPB220_RS01565	COG1122	ATPase activity
LPB220_RS01575	COG0310	cobalt ion transport
LPB220_RS01580	COG1846	Transcriptional regulator
LPB220_RS01595	COG1174	glycine betaine transport
LPB220_RS01600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LPB220_RS01605	COG2723	6-phospho-beta-galactosidase activity
LPB220_RS01610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LPB220_RS01615	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LPB220_RS01635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPB220_RS01640	COG0765	amino acid transport
LPB220_RS01645	COG0765	amino acid transport
LPB220_RS01650	COG1126	abc transporter atp-binding protein
LPB220_RS01690	COG1862	Preprotein translocase
LPB220_RS01695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LPB220_RS01700	COG4589	Belongs to the CDS family
LPB220_RS01705	COG0750	zinc metalloprotease
LPB220_RS01770	COG2176	DNA-directed DNA polymerase activity
LPB220_RS01780	COG0464	growth
LPB220_RS01785	COG2309	aminopeptidase activity
LPB220_RS01810	COG2814	Major facilitator Superfamily
LPB220_RS01820	COG1187	pseudouridine synthase activity
LPB220_RS01845	COG3118	belongs to the thioredoxin family
LPB220_RS01855	COG1164	Oligoendopeptidase f
LPB220_RS01890	COG1045	serine acetyltransferase
LPB220_RS01900	COG0215	cysteine-tRNA ligase activity
LPB220_RS01905	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LPB220_RS01915	COG3842	ATPase activity
LPB220_RS01920	COG0366	Alpha amylase catalytic
LPB220_RS01940	COG3688	RNA-binding protein containing a PIN domain
LPB220_RS01950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LPB220_RS01955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LPB220_RS02020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LPB220_RS02035	COG3237	CsbD-like
LPB220_RS02055	COG3830	Belongs to the UPF0237 family
LPB220_RS02065	COG0588	phosphoglycerate mutase activity
LPB220_RS02075	COG1876	peptidase activity
LPB220_RS02085	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LPB220_RS02105	COG0484	heat shock protein binding
LPB220_RS02110	COG3583	domain protein
LPB220_RS02110	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LPB220_RS02110	COG3064	Membrane
LPB220_RS02125	COG0351	phosphomethylpyrimidine kinase
LPB220_RS02130	COG4720	Psort location CytoplasmicMembrane, score
LPB220_RS02135	COG4475	Protein of unknown function (DUF436)
LPB220_RS02140	COG0544	peptidyl-prolyl cis-trans isomerase activity
LPB220_RS02145	COG3343	RNA polymerase activity
LPB220_RS02155	COG0504	CTP synthase activity
LPB220_RS02170	COG0191	fructose-bisphosphate aldolase activity
LPB220_RS02185	COG4555	ABC transporter
LPB220_RS02230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LPB220_RS02260	COG1131	(ABC) transporter
LPB220_RS02265	COG0842	Transport permease protein
LPB220_RS02270	COG4585	Histidine kinase
LPB220_RS02275	COG2197	response regulator
LPB220_RS02280	COG0028	Belongs to the TPP enzyme family
LPB220_RS02285	COG0440	acetolactate synthase activity
LPB220_RS02290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LPB220_RS02295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LPB220_RS02310	COG1126	abc transporter atp-binding protein
LPB220_RS02315	COG0765	amino acid transport
LPB220_RS02330	COG4862	establishment of competence for transformation
LPB220_RS02335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LPB220_RS02345	COG0719	Fe-S assembly protein
LPB220_RS02350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LPB220_RS02360	COG0719	Fe-S assembly protein
LPB220_RS02365	COG1686	Belongs to the peptidase S11 family
LPB220_RS02370	COG4166	transmembrane transport
LPB220_RS02375	COG0601	transmembrane transport
LPB220_RS02380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB220_RS02385	COG0444	Belongs to the ABC transporter superfamily
LPB220_RS02390	COG4608	Belongs to the ABC transporter superfamily
LPB220_RS02425	COG0527	aspartate kinase activity
LPB220_RS02430	COG1024	Enoyl-CoA hydratase
LPB220_RS02435	COG1846	Transcriptional regulator
LPB220_RS02440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPB220_RS02450	COG2070	2-Nitropropane dioxygenase
LPB220_RS02455	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LPB220_RS02460	COG1028	Short-chain dehydrogenase reductase Sdr
LPB220_RS02465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LPB220_RS02480	COG0439	Biotin carboxylase
LPB220_RS02485	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LPB220_RS02490	COG0825	malonyl-CoA metabolic process
LPB220_RS02505	COG3716	PTS system mannose fructose sorbose family IID component
LPB220_RS02510	COG3715	PTS system
LPB220_RS02520	COG1064	alcohol dehydrogenase
LPB220_RS02525	COG0561	phosphatase activity
LPB220_RS02530	COG2252	PERMEase
LPB220_RS02535	COG0802	atpase or kinase
LPB220_RS02540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LPB220_RS02545	COG1316	TRANSCRIPTIONal
LPB220_RS02555	COG0537	adenosine 5'-monophosphoramidase activity
LPB220_RS02560	COG1131	(ABC) transporter
LPB220_RS02575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LPB220_RS02580	COG0779	Required for maturation of 30S ribosomal subunits
LPB220_RS02585	COG0195	Participates in both transcription termination and antitermination
LPB220_RS02590	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LPB220_RS02610	COG1283	sodium-dependent phosphate transmembrane transporter activity
LPB220_RS02625	COG0656	L-ascorbic acid biosynthetic process
LPB220_RS02650	COG1113	amino acid transport
LPB220_RS02675	COG0768	penicillin binding
LPB220_RS02685	COG0513	Belongs to the DEAD box helicase family
LPB220_RS02690	COG0765	amino acid transport
LPB220_RS02695	COG1126	abc transporter atp-binding protein
LPB220_RS02705	COG0492	ferredoxin-NADP+ reductase activity
LPB220_RS02710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LPB220_RS02725	COG3579	cysteine-type endopeptidase activity
LPB220_RS02730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LPB220_RS02735	COG3331	DNA recombination
LPB220_RS02740	COG4474	Belongs to the UPF0398 family
LPB220_RS02745	COG3599	regulation of cell shape
LPB220_RS02755	COG0116	Belongs to the methyltransferase superfamily
LPB220_RS02765	COG1854	S-ribosylhomocysteine lyase activity
LPB220_RS02770	COG1418	mRNA catabolic process
LPB220_RS02775	COG0194	GDP metabolic process
LPB220_RS02780	COG1758	RNA polymerase activity
LPB220_RS02785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LPB220_RS02795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LPB220_RS02795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LPB220_RS02800	COG0631	protein serine/threonine phosphatase activity
LPB220_RS02805	COG2815	serine threonine protein kinase
LPB220_RS02805	COG0515	serine threonine protein kinase
LPB220_RS02815	COG4585	Histidine kinase
LPB220_RS02820	COG2197	response regulator
LPB220_RS02830	COG1098	S1 RNA binding domain
LPB220_RS02845	COG1739	Uncharacterized protein family UPF0029
LPB220_RS02850	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LPB220_RS02935	COG3557	Belongs to the UPF0374 family
LPB220_RS02945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPB220_RS02980	COG0519	Catalyzes the synthesis of GMP from XMP
LPB220_RS03015	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LPB220_RS03020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LPB220_RS03025	COG1534	Rna-binding protein
LPB220_RS03030	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LPB220_RS03035	COG1713	HD superfamily hydrolase involved in NAD metabolism
LPB220_RS03040	COG1335	isochorismatase
LPB220_RS03045	COG0799	negative regulation of ribosome biogenesis
LPB220_RS03050	COG2226	methyltransferase
LPB220_RS03070	COG0217	transcriptional regulatory protein
LPB220_RS03085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPB220_RS03090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LPB220_RS03100	COG0742	ribosomal rna small subunit methyltransferase
LPB220_RS03105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LPB220_RS03110	COG3480	Lon protease (S16) C-terminal proteolytic domain
LPB220_RS03115	COG0785	Cytochrome C biogenesis protein
LPB220_RS03125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB220_RS03130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPB220_RS03130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPB220_RS03135	COG4753	response regulator
LPB220_RS03135	COG2207	Transcriptional regulator
LPB220_RS03140	COG2972	Histidine kinase
LPB220_RS03145	COG4470	Protein conserved in bacteria
LPB220_RS03150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LPB220_RS03160	COG0133	tryptophan synthase activity
LPB220_RS03165	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LPB220_RS03175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LPB220_RS03180	COG1187	pseudouridine synthase activity
LPB220_RS03185	COG1217	gtp-binding protein TYPA
LPB220_RS03205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LPB220_RS03215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LPB220_RS03220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LPB220_RS03225	COG1799	cell septum assembly
LPB220_RS03240	COG3599	regulation of cell shape
LPB220_RS03245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LPB220_RS03255	COG0494	nUDIX hydrolase
LPB220_RS03265	COG0542	response to heat
LPB220_RS03270	COG4703	Protein of unknown function (DUF1797)
LPB220_RS03275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LPB220_RS03285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LPB220_RS03300	COG1175	transmembrane transport
LPB220_RS03305	COG0395	ABC-type sugar transport system, permease component
LPB220_RS03310	COG1621	beta-fructofuranosidase activity
LPB220_RS03325	COG0281	malic enzyme
LPB220_RS03330	COG0583	DNA-binding transcription factor activity
LPB220_RS03335	COG1570	exodeoxyribonuclease VII activity
LPB220_RS03340	COG1722	exodeoxyribonuclease VII activity
LPB220_RS03350	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LPB220_RS03355	COG1438	arginine binding
LPB220_RS03360	COG0497	DNA recombination
LPB220_RS03365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LPB220_RS03370	COG1307	EDD domain protein, DegV family
LPB220_RS03385	COG0588	phosphoglycerate mutase activity
LPB220_RS03390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPB220_RS03390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPB220_RS03395	COG3655	Transcriptional regulator
LPB220_RS03415	COG0803	Belongs to the bacterial solute-binding protein 9 family
LPB220_RS03435	COG0745	RESPONSE REGULATOR receiver
LPB220_RS03440	COG2205	protein histidine kinase activity
LPB220_RS03445	COG1136	(ABC) transporter
LPB220_RS03450	COG0577	efflux transmembrane transporter activity
LPB220_RS03475	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LPB220_RS03500	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
LPB220_RS03505	COG3620	sequence-specific DNA binding
LPB220_RS03520	COG0582	viral genome integration into host DNA
LPB220_RS03575	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LPB220_RS03805	COG0477	Major facilitator Superfamily
LPB220_RS03810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LPB220_RS03830	COG1136	(ABC) transporter
LPB220_RS03835	COG0577	efflux transmembrane transporter activity
LPB220_RS03840	COG4166	transmembrane transport
LPB220_RS03845	COG1695	Transcriptional regulator
LPB220_RS03865	COG0531	amino acid
LPB220_RS03875	COG1028	Short-chain dehydrogenase reductase Sdr
LPB220_RS03900	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LPB220_RS03905	COG0494	nUDIX hydrolase
LPB220_RS03915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LPB220_RS03925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LPB220_RS03930	COG4166	transmembrane transport
LPB220_RS03950	COG0708	Exodeoxyribonuclease III
LPB220_RS03960	COG2323	membrane
LPB220_RS03965	COG0768	penicillin binding
LPB220_RS03970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LPB220_RS03985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LPB220_RS04010	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LPB220_RS04025	COG0513	Belongs to the DEAD box helicase family
LPB220_RS04035	COG2827	Endonuclease containing a URI domain
LPB220_RS04040	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LPB220_RS04050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LPB220_RS04055	COG0204	Acyl-transferase
LPB220_RS04060	COG1596	polysaccharide export
LPB220_RS04060	COG1555	photosystem II stabilization
LPB220_RS04065	COG2333	competence protein COMEC
LPB220_RS04065	COG0658	competence protein
LPB220_RS04080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LPB220_RS04085	COG0433	COG0433 Predicted ATPase
LPB220_RS04100	COG2235	arginine
LPB220_RS04105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LPB220_RS04110	COG0549	Belongs to the carbamate kinase family
LPB220_RS04115	COG1288	antiporter activity
LPB220_RS04120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LPB220_RS04125	COG1438	arginine binding
LPB220_RS04130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LPB220_RS04145	COG1686	Belongs to the peptidase S11 family
LPB220_RS04170	COG4122	O-methyltransferase activity
LPB220_RS04175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LPB220_RS04185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LPB220_RS04190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPB220_RS04195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPB220_RS04200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LPB220_RS04205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LPB220_RS04215	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LPB220_RS04225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LPB220_RS04230	COG0297	glycogen (starch) synthase activity
LPB220_RS04235	COG3064	Membrane
LPB220_RS04245	COG0356	it plays a direct role in the translocation of protons across the membrane
LPB220_RS04250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LPB220_RS04255	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPB220_RS04260	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LPB220_RS04265	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LPB220_RS04275	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LPB220_RS04285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LPB220_RS04305	COG0488	(ABC) transporter
LPB220_RS04320	COG2814	Major facilitator Superfamily
LPB220_RS04325	COG2814	Major facilitator Superfamily
LPB220_RS04335	COG3442	glutamine amidotransferase
LPB220_RS04340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LPB220_RS04345	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LPB220_RS04355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPB220_RS04360	COG4932	domain protein
LPB220_RS04370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LPB220_RS04380	COG0251	oxidation-reduction process
LPB220_RS04385	COG1660	Displays ATPase and GTPase activities
LPB220_RS04390	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LPB220_RS04395	COG1481	regulation of sporulation
LPB220_RS04400	COG0492	ferredoxin-NADP+ reductase activity
LPB220_RS04405	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LPB220_RS04410	COG1970	mechanosensitive ion channel activity
LPB220_RS04415	COG0358	DNA primase activity
LPB220_RS04420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPB220_RS04425	COG2151	metal-sulfur cluster biosynthetic enzyme
LPB220_RS04430	COG1131	(ABC) transporter
LPB220_RS04455	COG0205	6-phosphofructokinase activity
LPB220_RS04460	COG0469	pyruvate kinase activity
LPB220_RS04470	COG0765	amino acid transport
LPB220_RS04475	COG1126	abc transporter atp-binding protein
LPB220_RS04485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LPB220_RS04490	COG0210	DNA helicase
LPB220_RS04505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPB220_RS04510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LPB220_RS04515	COG0196	riboflavin kinase activity
LPB220_RS04525	COG1393	Belongs to the ArsC family
LPB220_RS04535	COG0483	inositol monophosphate 1-phosphatase activity
LPB220_RS04540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LPB220_RS04540	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LPB220_RS04545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LPB220_RS04550	COG0573	inorganic phosphate transmembrane transporter activity
LPB220_RS04555	COG0581	inorganic phosphate transmembrane transporter activity
LPB220_RS04560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LPB220_RS04570	COG0704	Plays a role in the regulation of phosphate uptake
LPB220_RS04585	COG3279	Response regulator of the LytR AlgR family
LPB220_RS04590	COG1131	(ABC) transporter
LPB220_RS04600	COG1268	BioY protein
LPB220_RS04610	COG0745	RESPONSE REGULATOR receiver
LPB220_RS04615	COG5002	protein histidine kinase activity
LPB220_RS04625	COG0726	polysaccharide deacetylase
LPB220_RS04630	COG0513	Belongs to the DEAD box helicase family
LPB220_RS04635	COG0673	inositol 2-dehydrogenase activity
LPB220_RS04640	COG0463	Glycosyl transferase, family 2
LPB220_RS04645	COG1091	dTDP-4-dehydrorhamnose reductase activity
LPB220_RS04655	COG1216	Glycosyl transferase, family 2
LPB220_RS04660	COG0463	Glycosyl transferase, family 2
LPB220_RS04680	COG1215	transferase activity, transferring glycosyl groups
LPB220_RS04710	COG1368	sulfuric ester hydrolase activity
LPB220_RS04730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LPB220_RS04740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LPB220_RS04750	COG2131	deaminase
LPB220_RS04775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LPB220_RS04780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LPB220_RS04785	COG4109	DRTGG domain
LPB220_RS04790	COG0024	Methionine aminopeptidase
LPB220_RS04805	COG1846	Transcriptional regulator
LPB220_RS04820	COG4708	membrane
LPB220_RS04825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LPB220_RS04830	COG1597	lipid kinase activity
LPB220_RS04835	COG1523	belongs to the glycosyl hydrolase 13 family
LPB220_RS04840	COG1368	sulfuric ester hydrolase activity
LPB220_RS04845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LPB220_RS04850	COG0710	3-dehydroquinate dehydratase activity
LPB220_RS04860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LPB220_RS04865	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LPB220_RS04870	COG0287	Prephenate dehydrogenase
LPB220_RS04875	COG3679	Belongs to the UPF0342 family
LPB220_RS04880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LPB220_RS04885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LPB220_RS04890	COG0077	Prephenate dehydratase
LPB220_RS04900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPB220_RS04915	COG1131	(ABC) transporter
LPB220_RS04920	COG1132	(ABC) transporter
LPB220_RS04930	COG0135	phosphoribosylanthranilate isomerase activity
LPB220_RS04955	COG1132	(ABC) transporter
LPB220_RS04975	COG1131	(ABC) transporter
LPB220_RS04980	COG0789	Transcriptional regulator
LPB220_RS05010	COG3196	Protein conserved in bacteria
LPB220_RS05045	COG3620	sequence-specific DNA binding
LPB220_RS05060	COG0366	Alpha amylase catalytic
LPB220_RS05105	COG2226	methyltransferase
LPB220_RS05125	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPB220_RS05150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LPB220_RS05160	COG0716	FMN binding
LPB220_RS05170	COG0038	chloride channel
LPB220_RS05195	COG1397	ADP-ribosylglycohydrolase
LPB220_RS05235	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LPB220_RS05240	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LPB220_RS05260	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LPB220_RS05265	COG0038	chloride channel
LPB220_RS05275	COG0813	purine-nucleoside phosphorylase activity
LPB220_RS05290	COG0583	DNA-binding transcription factor activity
LPB220_RS05300	COG0543	2 iron, 2 sulfur cluster binding
LPB220_RS05305	COG0167	dihydroorotate dehydrogenase activity
LPB220_RS05310	COG0284	orotidine-5'-phosphate decarboxylase activity
LPB220_RS05350	COG1051	belongs to the nudix hydrolase family
LPB220_RS05355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB220_RS05390	COG0066	3-isopropylmalate dehydratase activity
LPB220_RS05415	COG0187	DNA topoisomerase II activity
LPB220_RS05425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPB220_RS05430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LPB220_RS05450	COG0539	negative regulation of cytoplasmic translation
LPB220_RS05475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPB220_RS05515	COG1104	cysteine desulfurase activity
LPB220_RS05520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPB220_RS05525	COG4116	CYTH
LPB220_RS05530	COG2357	RelA SpoT domain protein
LPB220_RS05540	COG0564	pseudouridine synthase activity
LPB220_RS05545	COG0280	phosphate acetyltransferase
LPB220_RS05555	COG1194	a g-specific adenine glycosylase
LPB220_RS05570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPB220_RS05575	COG4684	Psort location CytoplasmicMembrane, score
LPB220_RS05580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LPB220_RS05595	COG0534	Mate efflux family protein
LPB220_RS05610	COG1114	Component of the transport system for branched-chain amino acids
LPB220_RS05615	COG0785	Cytochrome C biogenesis protein
LPB220_RS05620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB220_RS05625	COG1053	succinate dehydrogenase
LPB220_RS05625	COG0431	NADPH-dependent FMN reductase
LPB220_RS05625	COG3976	FMN-binding domain protein
LPB220_RS05655	COG2837	iron assimilation
LPB220_RS05660	COG0672	)-iron permease
LPB220_RS05665	COG0805	protein transport
LPB220_RS05670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LPB220_RS05695	COG1397	ADP-ribosylglycohydrolase
LPB220_RS05720	COG2233	PERMEase
LPB220_RS05725	COG0534	Mate efflux family protein
LPB220_RS05730	COG0129	dihydroxy-acid dehydratase activity
LPB220_RS05735	COG1942	4-Oxalocrotonate Tautomerase
LPB220_RS05740	COG1435	thymidine kinase activity
LPB220_RS05750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LPB220_RS05755	COG2890	protein-(glutamine-N5) methyltransferase activity
LPB220_RS05775	COG0741	lytic transglycosylase activity
LPB220_RS05805	COG2188	Transcriptional regulator
LPB220_RS05815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LPB220_RS05820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LPB220_RS05830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPB220_RS05835	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LPB220_RS05840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LPB220_RS05850	COG3458	cephalosporin-C deacetylase activity
LPB220_RS05860	COG1136	(ABC) transporter
LPB220_RS05870	COG0095	Lipoate-protein ligase
LPB220_RS05875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPB220_RS05880	COG0508	dehydrogenase complex catalyzes the overall conversion of
LPB220_RS05885	COG0022	dehydrogenase e1 component
LPB220_RS05890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LPB220_RS05915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LPB220_RS05920	COG0758	DNA mediated transformation
LPB220_RS05935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LPB220_RS05950	COG1131	(ABC) transporter
LPB220_RS05950	COG1716	ATPase activity
LPB220_RS05950	COG0842	Transport permease protein
LPB220_RS05965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPB220_RS05970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LPB220_RS05990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LPB220_RS06005	COG1132	(ABC) transporter
LPB220_RS06030	COG0222	ribosome binding
LPB220_RS06035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LPB220_RS06045	COG1705	Flagellar rod assembly protein muramidase FlgJ
LPB220_RS06045	COG1388	LysM domain
LPB220_RS06065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LPB220_RS06080	COG1940	carbohydrate kinase activity
LPB220_RS06090	COG0488	(ABC) transporter
LPB220_RS06095	COG0617	tRNA 3'-terminal CCA addition
LPB220_RS06100	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LPB220_RS06105	COG1307	EDD domain protein, DegV family
LPB220_RS06120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LPB220_RS06120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LPB220_RS06120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LPB220_RS06125	COG1105	Belongs to the carbohydrate kinase PfkB family
LPB220_RS06130	COG1349	DNA-binding transcription factor activity
LPB220_RS06160	COG1837	Belongs to the UPF0109 family
LPB220_RS06170	COG1011	Hydrolase
LPB220_RS06210	COG0561	phosphatase activity
LPB220_RS06215	COG2195	Cleaves the N-terminal amino acid of tripeptides
LPB220_RS06220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LPB220_RS06230	COG0540	Belongs to the ATCase OTCase family
LPB220_RS06235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LPB220_RS06245	COG2824	Alkylphosphonate utilization operon protein PhnA
LPB220_RS06265	COG4555	ABC transporter
LPB220_RS06270	COG1051	belongs to the nudix hydrolase family
LPB220_RS06310	COG1131	(ABC) transporter
LPB220_RS06330	COG0765	amino acid transport
LPB220_RS06335	COG1126	abc transporter atp-binding protein
LPB220_RS06340	COG1132	(ABC) transporter
LPB220_RS06345	COG1132	(ABC) transporter
LPB220_RS06360	COG0017	Asparaginyl-tRNA synthetase
LPB220_RS06365	COG0436	Aminotransferase
LPB220_RS06375	COG1846	Transcriptional regulator
LPB220_RS06380	COG3022	response to hydroperoxide
LPB220_RS06390	COG1272	protein, Hemolysin III
LPB220_RS06395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LPB220_RS06410	COG1132	(ABC) transporter
LPB220_RS06415	COG1132	(ABC) transporter
LPB220_RS06420	COG2315	Protein conserved in bacteria
LPB220_RS06425	COG3142	Participates in the control of copper homeostasis
LPB220_RS06445	COG1079	Belongs to the binding-protein-dependent transport system permease family
LPB220_RS06450	COG4603	Belongs to the binding-protein-dependent transport system permease family
LPB220_RS06455	COG3845	ABC transporter
LPB220_RS06460	COG1744	ABC transporter substrate-binding protein PnrA-like
LPB220_RS06470	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LPB220_RS06480	COG2813	Specifically methylates the guanine in position
LPB220_RS06485	COG1072	(Pantothenic acid kinase))
LPB220_RS06525	COG1573	uracil-dna glycosylase
LPB220_RS06565	COG0647	UMP catabolic process
LPB220_RS06580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LPB220_RS06585	COG0488	(ABC) transporter
LPB220_RS06590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LPB220_RS06600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LPB220_RS06605	COG0583	DNA-binding transcription factor activity
LPB220_RS06630	COG3711	transcriptional antiterminator
LPB220_RS06645	COG0698	ribose 5-phosphate isomerase
LPB220_RS06655	COG3775	system Galactitol-specific IIC component
LPB220_RS06675	COG1349	DNA-binding transcription factor activity
LPB220_RS06680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LPB220_RS06705	COG1104	cysteine desulfurase activity
LPB220_RS06730	COG1177	transmembrane transport
LPB220_RS06735	COG1177	transmembrane transport
LPB220_RS06740	COG3842	ATPase activity
LPB220_RS06760	COG0460	homoserine dehydrogenase
LPB220_RS06775	COG1418	mRNA catabolic process
LPB220_RS06830	COG1131	(ABC) transporter
LPB220_RS06855	COG3118	belongs to the thioredoxin family
LPB220_RS06865	COG4166	transmembrane transport
LPB220_RS06870	COG1363	Peptidase, m42
LPB220_RS06880	COG2197	response regulator
LPB220_RS06895	COG1136	(ABC) transporter
LPB220_RS06925	COG0745	RESPONSE REGULATOR receiver
LPB220_RS06930	COG2205	protein histidine kinase activity
LPB220_RS06975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LPB220_RS06985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LPB220_RS06995	COG0366	Alpha amylase catalytic
LPB220_RS07000	COG0395	ABC-type sugar transport system, permease component
LPB220_RS07005	COG1175	transmembrane transport
LPB220_RS07010	COG1653	transport
LPB220_RS07015	COG3345	alpha-galactosidase
LPB220_RS07020	COG2207	Transcriptional regulator
LPB220_RS07025	COG1609	Transcriptional regulator
LPB220_RS07030	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LPB220_RS07030	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LPB220_RS07050	COG0577	efflux transmembrane transporter activity
LPB220_RS07055	COG1136	(ABC) transporter
LPB220_RS07065	COG5002	protein histidine kinase activity
LPB220_RS07070	COG0745	RESPONSE REGULATOR receiver
LPB220_RS07080	COG1136	(ABC) transporter
LPB220_RS07100	COG0395	ABC-type sugar transport system, permease component
LPB220_RS07105	COG4209	transmembrane transport
LPB220_RS07115	COG2169	Transcriptional regulator
LPB220_RS07125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPB220_RS07145	COG0572	uridine kinase
LPB220_RS07165	COG1088	dTDP-glucose 4,6-dehydratase activity
LPB220_RS07175	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LPB220_RS07195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB220_RS07200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LPB220_RS07205	COG2384	SAM-dependent methyltransferase
LPB220_RS07210	COG0625	glutathione transferase activity
LPB220_RS07215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LPB220_RS07230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LPB220_RS07260	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LPB220_RS07260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LPB220_RS07330	COG0582	viral genome integration into host DNA
LPB220_RS07365	COG0300	oxidoreductase activity
LPB220_RS07380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LPB220_RS07400	COG1074	ATP-dependent DNA helicase activity
LPB220_RS07405	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LPB220_RS07410	COG0386	Belongs to the glutathione peroxidase family
LPB220_RS07415	COG1132	(ABC) transporter
LPB220_RS07420	COG1132	(ABC) transporter
LPB220_RS07455	COG4989	oxidoreductase activity
LPB220_RS07460	COG1668	transmembrane transport
LPB220_RS07465	COG4152	abc transporter atp-binding protein
LPB220_RS07475	COG1476	TRANSCRIPTIONal
LPB220_RS07495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPB220_RS07495	COG0072	phenylalanine-tRNA ligase activity
LPB220_RS07520	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LPB220_RS07530	COG3527	Alpha-acetolactate decarboxylase
LPB220_RS07535	COG0457	Tetratricopeptide repeat
LPB220_RS07540	COG0628	permease
LPB220_RS07545	COG2706	6-phosphogluconolactonase activity
LPB220_RS07555	COG0148	phosphopyruvate hydratase activity
LPB220_RS07570	COG0560	Phosphoserine phosphatase
LPB220_RS07575	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LPB220_RS07580	COG0187	DNA topoisomerase II activity
LPB220_RS07585	COG0546	phosphoglycolate phosphatase activity
LPB220_RS07595	COG0772	Belongs to the SEDS family
LPB220_RS07600	COG2855	membrane
LPB220_RS07605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LPB220_RS07605	COG1199	ATP-dependent helicase activity
LPB220_RS07615	COG2177	Part of the ABC transporter FtsEX involved in
LPB220_RS07620	COG2884	Cell division ATP-binding protein ftsE
LPB220_RS07635	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LPB220_RS07650	COG1078	dGTPase activity
LPB220_RS07660	COG2348	transferase activity, transferring amino-acyl groups
LPB220_RS07670	COG0149	triose-phosphate isomerase activity
LPB220_RS07675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LPB220_RS07680	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LPB220_RS07685	COG0772	Belongs to the SEDS family
LPB220_RS07695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LPB220_RS07710	COG0577	efflux transmembrane transporter activity
LPB220_RS07715	COG1136	(ABC) transporter
LPB220_RS07720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB220_RS07725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPB220_RS07730	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LPB220_RS07735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LPB220_RS07740	COG4443	Transcriptional Coactivator p15 (PC4)
LPB220_RS07760	COG0477	Major facilitator Superfamily
LPB220_RS07765	COG0826	peptidase U32
LPB220_RS07790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LPB220_RS07795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LPB220_RS07820	COG2183	response to ionizing radiation
LPB220_RS07825	COG0701	Predicted permease
LPB220_RS07830	COG3689	TIGRFAM TIGR03943 family protein
LPB220_RS07835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LPB220_RS07840	COG0552	protein localization to endoplasmic reticulum
LPB220_RS07845	COG0561	phosphatase activity
LPB220_RS07850	COG0561	phosphatase activity
LPB220_RS07855	COG1196	nuclear chromosome segregation
LPB220_RS07860	COG0571	ribonuclease III activity
LPB220_RS07870	COG2832	Protein of unknown function (DUF454)
LPB220_RS07880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LPB220_RS07885	COG5002	protein histidine kinase activity
LPB220_RS07890	COG0745	RESPONSE REGULATOR receiver
LPB220_RS07905	COG0438	transferase activity, transferring glycosyl groups
LPB220_RS07915	COG2226	methyltransferase
LPB220_RS07920	COG1309	transcriptional regulator
LPB220_RS07925	COG1609	Transcriptional regulator
LPB220_RS07930	COG0006	proline dipeptidase activity
LPB220_RS07940	COG1959	2 iron, 2 sulfur cluster binding
LPB220_RS07955	COG1136	(ABC) transporter
LPB220_RS07960	COG1914	H( )-stimulated, divalent metal cation uptake system
LPB220_RS07970	COG3615	Tellurite resistance protein tehB
LPB220_RS07970	COG0500	methyltransferase
LPB220_RS07975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LPB220_RS07980	COG0557	exoribonuclease II activity
LPB220_RS07990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LPB220_RS07995	COG2814	Major facilitator Superfamily
LPB220_RS08000	COG0237	dephospho-CoA kinase activity
LPB220_RS08005	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LPB220_RS08015	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LPB220_RS08025	COG1132	(ABC) transporter
LPB220_RS08045	COG0686	Belongs to the AlaDH PNT family
LPB220_RS08050	COG1702	phosphate starvation-inducible protein PhoH
LPB220_RS08070	COG0528	UMP kinase activity
LPB220_RS08075	COG0081	regulation of translation
LPB220_RS08080	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LPB220_RS08095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LPB220_RS08100	COG0346	lactoylglutathione lyase activity
LPB220_RS08105	COG0697	spore germination
LPB220_RS08105	COG1674	ftsk spoiiie
LPB220_RS08135	COG0697	spore germination
LPB220_RS08145	COG0488	(ABC) transporter
LPB220_RS08150	COG1393	Belongs to the ArsC family
LPB220_RS08155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LPB220_RS08170	COG4467	Involved in initiation control of chromosome replication
LPB220_RS08175	COG0470	DNA polymerase III
LPB220_RS08180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LPB220_RS08185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPB220_RS08190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LPB220_RS08190	COG0617	tRNA 3'-terminal CCA addition
LPB220_RS08190	COG0517	IMP dehydrogenase activity
LPB220_RS08235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LPB220_RS08245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LPB220_RS08250	COG0626	cystathionine gamma-synthase activity
LPB220_RS08260	COG2244	polysaccharide biosynthetic process
LPB220_RS08265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LPB220_RS08280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LPB220_RS08295	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LPB220_RS08305	COG2188	Transcriptional regulator
LPB220_RS08315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LPB220_RS08320	COG4120	Belongs to the binding-protein-dependent transport system permease family
LPB220_RS08330	COG1253	flavin adenine dinucleotide binding
LPB220_RS08335	COG3711	transcriptional antiterminator
LPB220_RS08340	COG0628	permease
LPB220_RS08345	COG1119	ATPase activity
LPB220_RS08350	COG0025	NhaP-type Na H and K H
LPB220_RS08360	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LPB220_RS08365	COG1242	4 iron, 4 sulfur cluster binding
LPB220_RS08370	COG0671	phosphoesterase, PA-phosphatase related
LPB220_RS08375	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LPB220_RS08385	COG0569	domain protein
LPB220_RS08405	COG1187	pseudouridine synthase activity
LPB220_RS08410	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LPB220_RS08415	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LPB220_RS08420	COG4974	Belongs to the 'phage' integrase family
LPB220_RS08425	COG0517	IMP dehydrogenase activity
LPB220_RS08440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LPB220_RS08465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPB220_RS08470	COG1254	Belongs to the acylphosphatase family
LPB220_RS08480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LPB220_RS08485	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LPB220_RS08510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LPB220_RS08520	COG0778	Nitroreductase
LPB220_RS08525	COG1484	DNA-dependent DNA replication
LPB220_RS08535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LPB220_RS08545	COG2190	(PTS) system
LPB220_RS08545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LPB220_RS08545	COG1263	PTS System
LPB220_RS08550	COG0745	RESPONSE REGULATOR receiver
LPB220_RS08555	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LPB220_RS08560	COG2268	Band 7 protein
LPB220_RS08580	COG0501	Belongs to the peptidase M48B family
LPB220_RS08585	COG1704	LemA family
LPB220_RS08590	COG0357	Ribosomal RNA small subunit methyltransferase G
LPB220_RS08600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPB220_RS08605	COG4221	oxidoreductase activity
LPB220_RS08660	COG1464	Belongs to the NlpA lipoprotein family
LPB220_RS08665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPB220_RS08670	COG1473	amidohydrolase
LPB220_RS08685	COG1063	alcohol dehydrogenase
LPB220_RS08720	COG1442	glycosyl transferase family 8
LPB220_RS08720	COG1216	Glycosyl transferase, family 2
LPB220_RS08725	COG1442	glycosyl transferase family 8
LPB220_RS08730	COG1335	isochorismatase
LPB220_RS08735	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LPB220_RS08740	COG0436	Aminotransferase
LPB220_RS08745	COG0589	response to stress
LPB220_RS08750	COG0561	phosphatase activity
LPB220_RS08755	COG0252	asparaginase activity
LPB220_RS08760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LPB220_RS08765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LPB220_RS08770	COG0736	holo-[acyl-carrier-protein] synthase activity
LPB220_RS08775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LPB220_RS08780	COG0653	protein targeting
LPB220_RS08785	COG0531	amino acid
LPB220_RS08795	COG0789	Transcriptional regulator
LPB220_RS08800	COG1482	cell wall glycoprotein biosynthetic process
LPB220_RS08805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LPB220_RS08820	COG1132	(ABC) transporter
LPB220_RS08835	COG0242	peptide deformylase activity
LPB220_RS08845	COG1940	carbohydrate kinase activity
LPB220_RS08850	COG1263	PTS System
LPB220_RS08850	COG2190	(PTS) system
LPB220_RS08850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LPB220_RS08855	COG1621	beta-fructofuranosidase activity
LPB220_RS08860	COG1609	Transcriptional regulator
LPB220_RS08890	COG0006	proline dipeptidase activity
LPB220_RS08895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LPB220_RS08910	COG1136	(ABC) transporter
LPB220_RS08920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LPB220_RS08925	COG0629	single-stranded DNA binding
LPB220_RS08950	COG0737	Belongs to the 5'-nucleotidase family
LPB220_RS08955	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LPB220_RS08960	COG1228	amidohydrolase
LPB220_RS08965	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LPB220_RS08975	COG3404	Formiminotransferase-cyclodeaminase
LPB220_RS08990	COG0531	amino acid
LPB220_RS08995	COG2986	histidine ammonia-lyase
LPB220_RS09020	COG0366	Alpha amylase catalytic
LPB220_RS09035	COG0569	domain protein
LPB220_RS09040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LPB220_RS09050	COG0110	maltose O-acetyltransferase activity
LPB220_RS09055	COG1349	DNA-binding transcription factor activity
LPB220_RS09060	COG0561	phosphatase activity
LPB220_RS09075	COG1063	alcohol dehydrogenase
LPB220_RS09080	COG1230	cation diffusion facilitator family transporter
LPB220_RS09110	COG1122	ATPase activity
LPB220_RS09120	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPB220_RS09140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LPB220_RS09165	COG2205	protein histidine kinase activity
LPB220_RS09170	COG0745	RESPONSE REGULATOR receiver
LPB220_RS09180	COG2723	6-phospho-beta-galactosidase activity
LPB220_RS09190	COG0028	Belongs to the TPP enzyme family
LPB220_RS09215	COG0561	phosphatase activity
LPB220_RS09230	COG0747	negative chemotaxis
LPB220_RS09235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB220_RS09240	COG0601	transmembrane transport
LPB220_RS09250	COG2226	methyltransferase
LPB220_RS09250	COG1073	alpha beta
LPB220_RS09260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LPB220_RS09275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPB220_RS09275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPB220_RS09290	COG0167	dihydroorotate dehydrogenase activity
LPB220_RS09295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LPB220_RS09305	COG0668	transmembrane transport
LPB220_RS09310	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LPB220_RS09325	COG1193	negative regulation of DNA recombination
LPB220_RS09345	COG0681	Belongs to the peptidase S26 family
LPB220_RS09350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LPB220_RS09355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPB220_RS09360	COG1882	Formate acetyltransferase
LPB220_RS09380	COG3425	synthase
LPB220_RS09400	COG1304	FMN binding
LPB220_RS09415	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LPB220_RS09420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LPB220_RS09465	COG1606	tRNA processing
LPB220_RS09470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LPB220_RS09475	COG3875	lactate racemase activity
LPB220_RS09480	COG1691	(AIR) carboxylase
LPB220_RS09485	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LPB220_RS09490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LPB220_RS09495	COG2081	HI0933 family
LPB220_RS09545	COG0456	acetyltransferase
LPB220_RS09550	COG1214	PFAM Peptidase M22, glycoprotease
LPB220_RS09555	COG5503	Protein of unknown function (DUF1447)
LPB220_RS09570	COG0174	glutamine synthetase
LPB220_RS09575	COG0789	Transcriptional regulator
LPB220_RS09585	COG0126	phosphoglycerate kinase activity
LPB220_RS09590	COG0366	Alpha amylase catalytic
LPB220_RS09600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LPB220_RS09625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LPB220_RS09630	COG3481	metal-dependent phosphohydrolase, HD sub domain
LPB220_RS09645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LPB220_RS09650	COG1162	GTPase activity
LPB220_RS09685	COG0084	hydrolase, TatD family'
LPB220_RS09690	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LPB220_RS09700	COG1847	R3H domain protein
LPB220_RS09705	COG0706	membrane insertase activity
LPB220_RS09710	COG0594	ribonuclease P activity
LPB220_RS09745	COG0653	protein targeting
LPB220_RS09765	COG0201	protein transport
LPB220_RS09840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LPB220_RS09885	COG0756	dUTP diphosphatase activity
LPB220_RS09890	COG4932	domain protein
LPB220_RS09890	COG1388	LysM domain
LPB220_RS09895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LPB220_RS09900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LPB220_RS09905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LPB220_RS09925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LPB220_RS10000	COG0166	Belongs to the GPI family
LPB220_RS10020	COG1132	(ABC) transporter
LPB220_RS10035	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LPB220_RS10050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LPB220_RS10070	COG3201	nicotinamide mononucleotide transporter
LPB220_RS10075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LPB220_RS10095	COG0542	response to heat
LPB220_RS10100	COG4463	regulation of RNA biosynthetic process
LPB220_RS10110	COG3250	beta-galactosidase activity
LPB220_RS10135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LPB220_RS10165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LPB220_RS10170	COG2321	neutral zinc metallopeptidase
LPB220_RS10175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LPB220_RS10180	COG0564	pseudouridine synthase activity
LPB220_RS10195	COG0438	transferase activity, transferring glycosyl groups
LPB220_RS10205	COG0562	UDP-galactopyranose mutase
LPB220_RS10220	COG1442	glycosyl transferase family 8
LPB220_RS10220	COG1216	Glycosyl transferase, family 2
LPB220_RS10235	COG0297	glycogen (starch) synthase activity
LPB220_RS10245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LPB220_RS10250	COG0489	protein tyrosine kinase activity
LPB220_RS10255	COG3944	biosynthesis protein
LPB220_RS10260	COG4464	protein tyrosine phosphatase activity
LPB220_RS10265	COG1316	TRANSCRIPTIONal
LPB220_RS10270	COG0602	queuosine metabolic process
LPB220_RS10290	COG1328	CTP reductase activity
LPB220_RS10300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LPB220_RS10315	COG0285	dihydrofolate synthase activity
LPB220_RS10325	COG3906	Belongs to the UPF0473 family
LPB220_RS10330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LPB220_RS10335	COG4472	Bacterial protein of unknown function (DUF965)
LPB220_RS10345	COG1393	Belongs to the ArsC family
LPB220_RS10355	COG1546	Belongs to the CinA family
LPB220_RS10355	COG1058	Belongs to the CinA family
LPB220_RS10370	COG2818	Glycosylase
LPB220_RS10380	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LPB220_RS10395	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LPB220_RS10400	COG1438	arginine binding
LPB220_RS10405	COG0018	arginyl-trna synthetase
LPB220_RS10420	COG1780	Probably involved in ribonucleotide reductase function
LPB220_RS10435	COG0058	SHG alpha-glucan phosphorylase activity
LPB220_RS10440	COG1640	4-alpha-glucanotransferase
LPB220_RS10445	COG2182	Extracellular solute-binding protein
LPB220_RS10450	COG1175	transmembrane transport
LPB220_RS10455	COG3833	ABC-type maltose transport systems, permease component
LPB220_RS10460	COG5521	maltodextrose utilization protein MalA
LPB220_RS10465	COG1609	Transcriptional regulator
LPB220_RS10470	COG1523	belongs to the glycosyl hydrolase 13 family
LPB220_RS10475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPB220_RS10490	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LPB220_RS10495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPB220_RS10500	COG1696	Membrane protein involved in D-alanine export
LPB220_RS10540	COG1511	domain protein
LPB220_RS10540	COG1511	domain protein
LPB220_RS10555	COG1116	anion transmembrane transporter activity
LPB220_RS10560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB220_RS10565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB220_RS10575	COG0305	Participates in initiation and elongation during chromosome replication
LPB220_RS10580	COG0359	binds to the 23S rRNA
LPB220_RS10595	COG0494	nUDIX hydrolase
LPB220_RS10610	COG1760	l-serine dehydratase
LPB220_RS10615	COG1760	l-serine dehydratase
LPB220_RS10625	COG0741	lytic transglycosylase activity
LPB220_RS10630	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPB220_RS10635	COG1122	ATPase activity
LPB220_RS10640	COG1122	ATPase activity
LPB220_RS10645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LPB220_RS10655	COG0612	Peptidase, M16
LPB220_RS10660	COG0612	Peptidase, M16
LPB220_RS10670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LPB220_RS10675	COG0517	IMP dehydrogenase activity
LPB220_RS10675	COG0516	GMP reductase activity
LPB220_RS10680	COG0180	Tryptophanyl-tRNA synthetase
LPB220_RS10685	COG0488	(ABC) transporter
LPB220_RS10710	COG3290	protein histidine kinase activity
LPB220_RS10720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LPB220_RS10725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPB220_RS10730	COG1475	DNA binding