locus-tag	class	description
DDV21_RS00010	COG0592	DNA-directed DNA polymerase activity
DDV21_RS00040	COG3620	sequence-specific DNA binding
DDV21_RS00045	COG0012	GTP binding
DDV21_RS00055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DDV21_RS00060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DDV21_RS00085	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DDV21_RS00090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDV21_RS00200	COG1792	Involved in formation and maintenance of cell shape
DDV21_RS00240	COG0436	Aminotransferase
DDV21_RS00250	COG0416	fatty acid biosynthetic process
DDV21_RS00255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDV21_RS00260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DDV21_RS00265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDV21_RS00270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DDV21_RS00275	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DDV21_RS00280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DDV21_RS00310	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS00315	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS00320	COG3715	PTS system
DDV21_RS00325	COG3716	PTS system mannose fructose sorbose family IID component
DDV21_RS00330	COG1979	alcohol dehydrogenase
DDV21_RS00340	COG0673	inositol 2-dehydrogenase activity
DDV21_RS00345	COG5632	N-Acetylmuramoyl-L-alanine amidase
DDV21_RS00345	COG3409	Peptidoglycan-binding domain 1 protein
DDV21_RS00370	COG0151	Belongs to the GarS family
DDV21_RS00375	COG1683	Conserved Protein
DDV21_RS00380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DDV21_RS00390	COG1794	racemase activity, acting on amino acids and derivatives
DDV21_RS00405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDV21_RS00410	COG1053	succinate dehydrogenase
DDV21_RS00410	COG3976	FMN-binding domain protein
DDV21_RS00420	COG2255	four-way junction helicase activity
DDV21_RS00430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDV21_RS00450	COG0534	Mate efflux family protein
DDV21_RS00455	COG0051	transcription antitermination factor activity, RNA binding
DDV21_RS00460	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DDV21_RS00500	COG0255	Belongs to the universal ribosomal protein uL29 family
DDV21_RS00520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DDV21_RS00525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDV21_RS00545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DDV21_RS00560	COG0201	protein transport
DDV21_RS00565	COG0563	adenylate kinase activity
DDV21_RS00590	COG0202	RNA polymerase activity
DDV21_RS00690	COG1335	isochorismatase
DDV21_RS00705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DDV21_RS00715	COG1121	(ABC) transporter
DDV21_RS00720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDV21_RS00730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDV21_RS00755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DDV21_RS00760	COG1459	type II secretion system
DDV21_RS00765	COG4537	Required for transformation and DNA binding
DDV21_RS00790	COG0827	DNA restriction-modification system
DDV21_RS00805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDV21_RS00810	COG1363	Peptidase, m42
DDV21_RS00820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDV21_RS00830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS00830	COG1263	PTS System
DDV21_RS00830	COG2190	(PTS) system
DDV21_RS00850	COG4585	Histidine kinase
DDV21_RS00855	COG2197	response regulator
DDV21_RS00865	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS00875	COG3715	PTS system
DDV21_RS00880	COG3716	PTS system mannose fructose sorbose family IID component
DDV21_RS00890	COG1737	Transcriptional regulator
DDV21_RS00895	COG1263	PTS System
DDV21_RS00895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS00920	COG4120	Belongs to the binding-protein-dependent transport system permease family
DDV21_RS00935	COG0459	protein refolding
DDV21_RS00955	COG0564	pseudouridine synthase activity
DDV21_RS00960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDV21_RS00990	COG2070	2-Nitropropane dioxygenase
DDV21_RS00995	COG1733	regulation of RNA biosynthetic process
DDV21_RS01000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDV21_RS01010	COG2190	(PTS) system
DDV21_RS01010	COG1263	PTS System
DDV21_RS01010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS01015	COG2723	6-phospho-beta-galactosidase activity
DDV21_RS01095	COG1674	ftsk spoiiie
DDV21_RS01105	COG2946	Replication initiation factor
DDV21_RS01165	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDV21_RS01165	COG3942	CHAP domain
DDV21_RS01200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DDV21_RS01210	COG2264	protein methyltransferase activity
DDV21_RS01215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DDV21_RS01220	COG1609	Transcriptional regulator
DDV21_RS01225	COG2190	(PTS) system
DDV21_RS01225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS01225	COG1263	PTS System
DDV21_RS01235	COG1609	Transcriptional regulator
DDV21_RS01245	COG1621	beta-fructofuranosidase activity
DDV21_RS01260	COG1902	pentaerythritol trinitrate reductase activity
DDV21_RS01285	COG1396	sequence-specific DNA binding
DDV21_RS01305	COG2226	methyltransferase
DDV21_RS01315	COG1131	(ABC) transporter
DDV21_RS01330	COG0318	PFAM AMP-dependent synthetase and ligase
DDV21_RS01335	COG1136	(ABC) transporter
DDV21_RS01355	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DDV21_RS01370	COG2188	Transcriptional regulator
DDV21_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS01375	COG1263	PTS System
DDV21_RS01380	COG0366	Alpha amylase catalytic
DDV21_RS01385	COG3590	peptidase
DDV21_RS01410	COG4463	regulation of RNA biosynthetic process
DDV21_RS01415	COG0542	response to heat
DDV21_RS01420	COG1234	tRNA 3'-trailer cleavage
DDV21_RS01435	COG0673	inositol 2-dehydrogenase activity
DDV21_RS01455	COG3730	PTS system glucitol sorbitol-specific
DDV21_RS01460	COG3732	PTS system glucitol sorbitol-specific
DDV21_RS01495	COG0166	Belongs to the GPI family
DDV21_RS01505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS01505	COG3711	transcriptional antiterminator
DDV21_RS01515	COG3730	PTS system glucitol sorbitol-specific
DDV21_RS01520	COG3732	PTS system glucitol sorbitol-specific
DDV21_RS01535	COG1472	Belongs to the glycosyl hydrolase 3 family
DDV21_RS01550	COG1473	amidohydrolase
DDV21_RS01555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDV21_RS01560	COG0705	Rhomboid family
DDV21_RS01560	COG0457	Tetratricopeptide repeat
DDV21_RS01565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDV21_RS01570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DDV21_RS01590	COG2832	Protein of unknown function (DUF454)
DDV21_RS01595	COG0756	dUTP diphosphatase activity
DDV21_RS01635	COG1522	sequence-specific DNA binding
DDV21_RS01645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDV21_RS01655	COG0137	argininosuccinate synthase activity
DDV21_RS01665	COG0594	ribonuclease P activity
DDV21_RS01730	COG1902	pentaerythritol trinitrate reductase activity
DDV21_RS01735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DDV21_RS01765	COG0673	inositol 2-dehydrogenase activity
DDV21_RS01780	COG0084	hydrolase, TatD family'
DDV21_RS01835	COG2017	converts alpha-aldose to the beta-anomer
DDV21_RS01840	COG1162	GTPase activity
DDV21_RS01865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDV21_RS01875	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DDV21_RS01880	COG0049	tRNA binding
DDV21_RS01885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DDV21_RS01905	COG0126	phosphoglycerate kinase activity
DDV21_RS01915	COG0789	Transcriptional regulator
DDV21_RS01920	COG0174	glutamine synthetase
DDV21_RS01925	COG3942	CHAP domain
DDV21_RS01935	COG5503	Protein of unknown function (DUF1447)
DDV21_RS01940	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDV21_RS01950	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDV21_RS01975	COG2081	HI0933 family
DDV21_RS01980	COG0129	dihydroxy-acid dehydratase activity
DDV21_RS01995	COG0419	ATPase involved in DNA repair
DDV21_RS02000	COG2151	metal-sulfur cluster biosynthetic enzyme
DDV21_RS02020	COG0745	RESPONSE REGULATOR receiver
DDV21_RS02025	COG5002	protein histidine kinase activity
DDV21_RS02030	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DDV21_RS02035	COG4989	oxidoreductase activity
DDV21_RS02060	COG2261	transglycosylase associated protein
DDV21_RS02105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS02105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDV21_RS02105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDV21_RS02110	COG3684	Belongs to the aldolase LacD family
DDV21_RS02125	COG1882	Formate acetyltransferase
DDV21_RS02145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDV21_RS02165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDV21_RS02170	COG0681	Belongs to the peptidase S26 family
DDV21_RS02175	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DDV21_RS02185	COG4509	Sortase family
DDV21_RS02200	COG1193	negative regulation of DNA recombination
DDV21_RS02215	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DDV21_RS02225	COG3118	belongs to the thioredoxin family
DDV21_RS02230	COG1194	a g-specific adenine glycosylase
DDV21_RS02240	COG0681	Belongs to the peptidase S26 family
DDV21_RS02265	COG3344	reverse transcriptase
DDV21_RS02285	COG1131	(ABC) transporter
DDV21_RS02295	COG1132	(ABC) transporter
DDV21_RS02310	COG3290	protein histidine kinase activity
DDV21_RS02315	COG0596	Alpha beta hydrolase
DDV21_RS02320	COG3620	sequence-specific DNA binding
DDV21_RS02330	COG0629	single-stranded DNA binding
DDV21_RS02335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DDV21_RS02370	COG0006	proline dipeptidase activity
DDV21_RS02375	COG2131	deaminase
DDV21_RS02380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DDV21_RS02390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDV21_RS02395	COG1621	beta-fructofuranosidase activity
DDV21_RS02400	COG1609	Transcriptional regulator
DDV21_RS02405	COG1621	beta-fructofuranosidase activity
DDV21_RS02410	COG2190	(PTS) system
DDV21_RS02410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS02410	COG1263	PTS System
DDV21_RS02415	COG1940	carbohydrate kinase activity
DDV21_RS02420	COG1737	Transcriptional regulator
DDV21_RS02425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDV21_RS02430	COG2723	6-phospho-beta-galactosidase activity
DDV21_RS02435	COG1482	cell wall glycoprotein biosynthetic process
DDV21_RS02490	COG0494	nUDIX hydrolase
DDV21_RS02500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DDV21_RS02525	COG0583	DNA-binding transcription factor activity
DDV21_RS02535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DDV21_RS02540	COG1733	regulation of RNA biosynthetic process
DDV21_RS02550	COG1917	Cupin 2, conserved barrel domain protein
DDV21_RS02550	COG2207	Transcriptional regulator
DDV21_RS02560	COG3394	polysaccharide catabolic process
DDV21_RS02650	COG0653	protein targeting
DDV21_RS02655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DDV21_RS02660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DDV21_RS02670	COG0736	holo-[acyl-carrier-protein] synthase activity
DDV21_RS02680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DDV21_RS02685	COG4989	oxidoreductase activity
DDV21_RS02690	COG0252	asparaginase activity
DDV21_RS02700	COG0561	phosphatase activity
DDV21_RS02705	COG0589	response to stress
DDV21_RS02710	COG0584	glycerophosphoryl diester phosphodiesterase
DDV21_RS02715	COG0436	Aminotransferase
DDV21_RS02725	COG1335	isochorismatase
DDV21_RS02735	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDV21_RS02740	COG0154	amidase activity
DDV21_RS02750	COG0477	Major facilitator Superfamily
DDV21_RS02755	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DDV21_RS02760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DDV21_RS02765	COG1534	Rna-binding protein
DDV21_RS02770	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DDV21_RS02775	COG1713	HD superfamily hydrolase involved in NAD metabolism
DDV21_RS02780	COG0799	negative regulation of ribosome biogenesis
DDV21_RS02790	COG2226	methyltransferase
DDV21_RS02795	COG1323	Belongs to the UPF0348 family
DDV21_RS02810	COG0217	transcriptional regulatory protein
DDV21_RS02815	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDV21_RS02820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDV21_RS02825	COG1464	Belongs to the NlpA lipoprotein family
DDV21_RS02850	COG4720	Psort location CytoplasmicMembrane, score
DDV21_RS02855	COG1122	ATPase activity
DDV21_RS02865	COG0569	domain protein
DDV21_RS02870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DDV21_RS02875	COG0357	Ribosomal RNA small subunit methyltransferase G
DDV21_RS02880	COG1704	LemA family
DDV21_RS02885	COG0501	Belongs to the peptidase M48B family
DDV21_RS02895	COG0745	RESPONSE REGULATOR receiver
DDV21_RS02910	COG1484	DNA-dependent DNA replication
DDV21_RS02915	COG1160	GTP binding
DDV21_RS02920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDV21_RS02935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DDV21_RS02940	COG0456	acetyltransferase
DDV21_RS02945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DDV21_RS02960	COG1254	Belongs to the acylphosphatase family
DDV21_RS02970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDV21_RS03000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DDV21_RS03015	COG0517	IMP dehydrogenase activity
DDV21_RS03020	COG0582	viral genome integration into host DNA
DDV21_RS03025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DDV21_RS03035	COG1187	pseudouridine synthase activity
DDV21_RS03040	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DDV21_RS03050	COG0569	domain protein
DDV21_RS03080	COG1131	(ABC) transporter
DDV21_RS03090	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DDV21_RS03095	COG0671	phosphoesterase, PA-phosphatase related
DDV21_RS03100	COG1242	4 iron, 4 sulfur cluster binding
DDV21_RS03105	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DDV21_RS03110	COG1119	ATPase activity
DDV21_RS03115	COG1253	flavin adenine dinucleotide binding
DDV21_RS03120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DDV21_RS03165	COG2188	Transcriptional regulator
DDV21_RS03170	COG2222	sugar isomerase
DDV21_RS03180	COG2188	Transcriptional regulator
DDV21_RS03195	COG3715	PTS system
DDV21_RS03200	COG3716	PTS system mannose fructose sorbose family IID component
DDV21_RS03215	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDV21_RS03220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DDV21_RS03225	COG1937	Protein conserved in bacteria
DDV21_RS03265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDV21_RS03270	COG3586	endonuclease activity
DDV21_RS03285	COG0456	acetyltransferase
DDV21_RS03285	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DDV21_RS03330	COG0742	ribosomal rna small subunit methyltransferase
DDV21_RS03335	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DDV21_RS03340	COG3480	Lon protease (S16) C-terminal proteolytic domain
DDV21_RS03350	COG0737	Belongs to the 5'-nucleotidase family
DDV21_RS03355	COG4470	Protein conserved in bacteria
DDV21_RS03360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DDV21_RS03370	COG1132	(ABC) transporter
DDV21_RS03375	COG1132	(ABC) transporter
DDV21_RS03385	COG1131	(ABC) transporter
DDV21_RS03395	COG4585	Histidine kinase
DDV21_RS03405	COG2197	response regulator
DDV21_RS03415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DDV21_RS03420	COG0512	Glutamine amidotransferase of anthranilate synthase
DDV21_RS03430	COG0134	indole-3-glycerol-phosphate synthase activity
DDV21_RS03435	COG0135	phosphoribosylanthranilate isomerase activity
DDV21_RS03440	COG0133	tryptophan synthase activity
DDV21_RS03445	COG0159	tryptophan synthase activity
DDV21_RS03450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DDV21_RS03455	COG0783	Belongs to the Dps family
DDV21_RS03460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DDV21_RS03470	COG1940	carbohydrate kinase activity
DDV21_RS03485	COG1217	gtp-binding protein TYPA
DDV21_RS03500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DDV21_RS03520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DDV21_RS03525	COG1799	cell septum assembly
DDV21_RS03540	COG3599	regulation of cell shape
DDV21_RS03545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DDV21_RS03560	COG0494	nUDIX hydrolase
DDV21_RS03570	COG0542	response to heat
DDV21_RS03575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDV21_RS03580	COG4703	Protein of unknown function (DUF1797)
DDV21_RS03585	COG0765	amino acid transport
DDV21_RS03590	COG1126	abc transporter atp-binding protein
DDV21_RS03615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DDV21_RS03620	COG1570	exodeoxyribonuclease VII activity
DDV21_RS03635	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DDV21_RS03640	COG1438	arginine binding
DDV21_RS03645	COG0497	DNA recombination
DDV21_RS03700	COG2755	lipolytic protein G-D-S-L family
DDV21_RS03705	COG4698	Protein conserved in bacteria
DDV21_RS03710	COG0776	regulation of translation
DDV21_RS03730	COG0588	phosphoglycerate mutase activity
DDV21_RS03735	COG0768	penicillin binding
DDV21_RS03740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DDV21_RS03755	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDV21_RS03765	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DDV21_RS03790	COG3414	Phosphotransferase system galactitol-specific IIB component
DDV21_RS03800	COG0513	Belongs to the DEAD box helicase family
DDV21_RS03805	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DDV21_RS03810	COG0204	Acyl-transferase
DDV21_RS03815	COG1596	polysaccharide export
DDV21_RS03815	COG1555	photosystem II stabilization
DDV21_RS03820	COG2333	competence protein COMEC
DDV21_RS03820	COG0658	competence protein
DDV21_RS03840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DDV21_RS03865	COG3976	FMN-binding domain protein
DDV21_RS03865	COG0431	NADPH-dependent FMN reductase
DDV21_RS03865	COG1053	succinate dehydrogenase
DDV21_RS03870	COG2508	Transcriptional regulator
DDV21_RS03895	COG0280	phosphate acetyltransferase
DDV21_RS03900	COG3426	butyrate kinase activity
DDV21_RS03940	COG0363	glucosamine-6-phosphate deaminase activity
DDV21_RS03960	COG4122	O-methyltransferase activity
DDV21_RS03970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DDV21_RS03975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDV21_RS03985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DDV21_RS03990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DDV21_RS03995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DDV21_RS04000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDV21_RS04060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDV21_RS04065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDV21_RS04070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DDV21_RS04105	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DDV21_RS04110	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DDV21_RS04160	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DDV21_RS04170	COG0513	Belongs to the DEAD box helicase family
DDV21_RS04190	COG0473	3-isopropylmalate dehydrogenase activity
DDV21_RS04195	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DDV21_RS04200	COG0066	3-isopropylmalate dehydratase activity
DDV21_RS04220	COG1956	GAF domain-containing protein
DDV21_RS04225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DDV21_RS04240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DDV21_RS04265	COG4109	DRTGG domain
DDV21_RS04285	COG4708	membrane
DDV21_RS04290	COG0561	phosphatase activity
DDV21_RS04295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DDV21_RS04300	COG1597	lipid kinase activity
DDV21_RS04305	COG1523	belongs to the glycosyl hydrolase 13 family
DDV21_RS04310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DDV21_RS04315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DDV21_RS04320	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DDV21_RS04325	COG0297	glycogen (starch) synthase activity
DDV21_RS04330	COG0058	SHG alpha-glucan phosphorylase activity
DDV21_RS04345	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DDV21_RS04360	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DDV21_RS04415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDV21_RS04435	COG0456	acetyltransferase
DDV21_RS04440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDV21_RS04440	COG0072	phenylalanine-tRNA ligase activity
DDV21_RS04445	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DDV21_RS04450	COG1074	ATP-dependent DNA helicase activity
DDV21_RS04530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DDV21_RS04535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDV21_RS04540	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DDV21_RS04550	COG0300	oxidoreductase activity
DDV21_RS04555	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DDV21_RS04555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DDV21_RS04560	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDV21_RS04580	COG2384	SAM-dependent methyltransferase
DDV21_RS04590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDV21_RS04595	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DDV21_RS04605	COG1088	dTDP-glucose 4,6-dehydratase activity
DDV21_RS04615	COG2706	6-phosphogluconolactonase activity
DDV21_RS04620	COG1051	belongs to the nudix hydrolase family
DDV21_RS04625	COG0628	permease
DDV21_RS04635	COG0028	Belongs to the TPP enzyme family
DDV21_RS04640	COG3527	Alpha-acetolactate decarboxylase
DDV21_RS04645	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DDV21_RS04670	COG0577	efflux transmembrane transporter activity
DDV21_RS04670	COG1136	(ABC) transporter
DDV21_RS04740	COG0488	(ABC) transporter
DDV21_RS04750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DDV21_RS04755	COG0022	dehydrogenase e1 component
DDV21_RS04755	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDV21_RS04760	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDV21_RS04770	COG0095	Lipoate-protein ligase
DDV21_RS04780	COG3442	glutamine amidotransferase
DDV21_RS04785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDV21_RS04790	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DDV21_RS04820	COG1857	crispr-associated protein
DDV21_RS04835	COG1518	maintenance of DNA repeat elements
DDV21_RS04840	COG2176	DNA-directed DNA polymerase activity
DDV21_RS04845	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDV21_RS04855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDV21_RS04865	COG1051	belongs to the nudix hydrolase family
DDV21_RS04870	COG0647	UMP catabolic process
DDV21_RS04885	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DDV21_RS04890	COG1518	maintenance of DNA repeat elements
DDV21_RS04895	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DDV21_RS04925	COG0481	GTPase activity
DDV21_RS04930	COG1902	pentaerythritol trinitrate reductase activity
DDV21_RS04935	COG0583	DNA-binding transcription factor activity
DDV21_RS04940	COG0583	DNA-binding transcription factor activity
DDV21_RS04950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDV21_RS04965	COG2814	Major facilitator Superfamily
DDV21_RS04970	COG0656	L-ascorbic acid biosynthetic process
DDV21_RS05045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDV21_RS05050	COG0656	L-ascorbic acid biosynthetic process
DDV21_RS05060	COG0656	L-ascorbic acid biosynthetic process
DDV21_RS05065	COG0656	L-ascorbic acid biosynthetic process
DDV21_RS05080	COG2264	protein methyltransferase activity
DDV21_RS05085	COG2723	6-phospho-beta-galactosidase activity
DDV21_RS05100	COG1263	PTS System
DDV21_RS05100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS05100	COG2190	(PTS) system
DDV21_RS05105	COG1737	Transcriptional regulator
DDV21_RS05110	COG2723	6-phospho-beta-galactosidase activity
DDV21_RS05125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DDV21_RS05145	COG1902	pentaerythritol trinitrate reductase activity
DDV21_RS05150	COG1733	regulation of RNA biosynthetic process
DDV21_RS05160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DDV21_RS05165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDV21_RS05180	COG0702	epimerase
DDV21_RS05190	COG1012	belongs to the aldehyde dehydrogenase family
DDV21_RS05195	COG0322	excinuclease ABC activity
DDV21_RS05205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDV21_RS05220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DDV21_RS05230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DDV21_RS05235	COG0813	purine-nucleoside phosphorylase activity
DDV21_RS05240	COG0583	DNA-binding transcription factor activity
DDV21_RS05245	COG1316	TRANSCRIPTIONal
DDV21_RS05265	COG2244	polysaccharide biosynthetic process
DDV21_RS05270	COG0562	UDP-galactopyranose mutase
DDV21_RS05285	COG3475	LICD family
DDV21_RS05290	COG1216	Glycosyl transferase, family 2
DDV21_RS05295	COG0438	transferase activity, transferring glycosyl groups
DDV21_RS05300	COG0438	transferase activity, transferring glycosyl groups
DDV21_RS05340	COG1122	ATPase activity
DDV21_RS05355	COG0167	dihydroorotate dehydrogenase activity
DDV21_RS05485	COG0551	DNA topoisomerase type I activity
DDV21_RS05485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDV21_RS05490	COG0542	response to heat
DDV21_RS05600	COG0284	orotidine-5'-phosphate decarboxylase activity
DDV21_RS05615	COG1881	PFAM PEBP family protein
DDV21_RS05630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DDV21_RS05640	COG0737	Belongs to the 5'-nucleotidase family
DDV21_RS05650	COG0187	DNA topoisomerase II activity
DDV21_RS05665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDV21_RS05685	COG0539	negative regulation of cytoplasmic translation
DDV21_RS05725	COG0398	Pfam SNARE associated Golgi protein
DDV21_RS05735	COG1131	(ABC) transporter
DDV21_RS05740	COG1725	Transcriptional regulator
DDV21_RS05750	COG0205	6-phosphofructokinase activity
DDV21_RS05755	COG0469	pyruvate kinase activity
DDV21_RS05770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDV21_RS05795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDV21_RS05800	COG3711	transcriptional antiterminator
DDV21_RS05800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS05805	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDV21_RS05815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDV21_RS05830	COG0110	maltose O-acetyltransferase activity
DDV21_RS05835	COG0673	inositol 2-dehydrogenase activity
DDV21_RS05840	COG2723	6-phospho-beta-galactosidase activity
DDV21_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
DDV21_RS05860	COG0561	phosphatase activity
DDV21_RS05870	COG0406	alpha-ribazole phosphatase activity
DDV21_RS05880	COG2723	6-phospho-beta-galactosidase activity
DDV21_RS05885	COG0628	permease
DDV21_RS05890	COG1442	glycosyl transferase family 8
DDV21_RS05900	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDV21_RS05905	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DDV21_RS05915	COG1104	cysteine desulfurase activity
DDV21_RS05930	COG2357	RelA SpoT domain protein
DDV21_RS05940	COG0564	pseudouridine synthase activity
DDV21_RS05945	COG0280	phosphate acetyltransferase
DDV21_RS05950	COG4221	oxidoreductase activity
DDV21_RS05970	COG2723	6-phospho-beta-galactosidase activity
DDV21_RS05975	COG0667	Aldo Keto reductase
DDV21_RS06000	COG2890	protein-(glutamine-N5) methyltransferase activity
DDV21_RS06005	COG0009	L-threonylcarbamoyladenylate synthase
DDV21_RS06030	COG1132	(ABC) transporter
DDV21_RS06040	COG2239	Acts as a magnesium transporter
DDV21_RS06050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDV21_RS06055	COG4684	Psort location CytoplasmicMembrane, score
DDV21_RS06060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDV21_RS06080	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DDV21_RS06085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDV21_RS06090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DDV21_RS06095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDV21_RS06100	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DDV21_RS06100	COG1328	CTP reductase activity
DDV21_RS06105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDV21_RS06120	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DDV21_RS06125	COG0110	maltose O-acetyltransferase activity
DDV21_RS06135	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDV21_RS06140	COG4605	iron ion homeostasis
DDV21_RS06145	COG4604	ABC transporter, ATP-binding protein
DDV21_RS06150	COG4607	ABC-type enterochelin transport system periplasmic component
DDV21_RS06155	COG0758	DNA mediated transformation
DDV21_RS06160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDV21_RS06175	COG1136	(ABC) transporter
DDV21_RS06185	COG0745	RESPONSE REGULATOR receiver
DDV21_RS06190	COG5002	protein histidine kinase activity
DDV21_RS06195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDV21_RS06205	COG4974	Belongs to the 'phage' integrase family
DDV21_RS06225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DDV21_RS06240	COG2188	Transcriptional regulator
DDV21_RS06270	COG0346	lactoylglutathione lyase activity
DDV21_RS06275	COG3764	Sortase (surface protein transpeptidase)
DDV21_RS06295	COG1079	Belongs to the binding-protein-dependent transport system permease family
DDV21_RS06300	COG4603	Belongs to the binding-protein-dependent transport system permease family
DDV21_RS06305	COG3845	ABC transporter
DDV21_RS06310	COG1744	ABC transporter substrate-binding protein PnrA-like
DDV21_RS06315	COG0295	cytidine deaminase activity
DDV21_RS06320	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DDV21_RS06330	COG2813	Specifically methylates the guanine in position
DDV21_RS06340	COG0268	Binds directly to 16S ribosomal RNA
DDV21_RS06345	COG5002	protein histidine kinase activity
DDV21_RS06350	COG0745	RESPONSE REGULATOR receiver
DDV21_RS06360	COG0704	Plays a role in the regulation of phosphate uptake
DDV21_RS06365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDV21_RS06370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDV21_RS06375	COG0581	inorganic phosphate transmembrane transporter activity
DDV21_RS06380	COG0573	inorganic phosphate transmembrane transporter activity
DDV21_RS06390	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DDV21_RS06390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DDV21_RS06395	COG0483	inositol monophosphate 1-phosphatase activity
DDV21_RS06400	COG4476	Belongs to the UPF0223 family
DDV21_RS06410	COG0196	riboflavin kinase activity
DDV21_RS06415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DDV21_RS06420	COG5263	repeat protein
DDV21_RS06420	COG0366	Alpha amylase catalytic
DDV21_RS06445	COG4129	membrane
DDV21_RS06455	COG1230	cation diffusion facilitator family transporter
DDV21_RS06470	COG2873	o-acetylhomoserine
DDV21_RS06480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDV21_RS06485	COG1115	amino acid carrier protein
DDV21_RS06490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DDV21_RS06500	COG1126	abc transporter atp-binding protein
DDV21_RS06505	COG0765	amino acid transport
DDV21_RS06510	COG0246	Mannitol dehydrogenase
DDV21_RS06515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS06520	COG3711	transcriptional antiterminator
DDV21_RS06525	COG2213	PTS system mannitol-specific
DDV21_RS06560	COG4977	sequence-specific DNA binding
DDV21_RS06560	COG1917	Cupin 2, conserved barrel domain protein
DDV21_RS06570	COG2272	Belongs to the type-B carboxylesterase lipase family
DDV21_RS06580	COG2190	(PTS) system
DDV21_RS06580	COG1263	PTS System
DDV21_RS06580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS06585	COG3711	transcriptional antiterminator
DDV21_RS06595	COG1177	transmembrane transport
DDV21_RS06600	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDV21_RS06610	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DDV21_RS06635	COG0285	dihydrofolate synthase activity
DDV21_RS06645	COG0460	homoserine dehydrogenase
DDV21_RS06675	COG0667	Aldo Keto reductase
DDV21_RS06680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDV21_RS06685	COG0110	maltose O-acetyltransferase activity
DDV21_RS06690	COG1028	Short-chain dehydrogenase reductase Sdr
DDV21_RS06710	COG0583	DNA-binding transcription factor activity
DDV21_RS06720	COG1028	Short-chain dehydrogenase reductase Sdr
DDV21_RS06750	COG2040	homocysteine
DDV21_RS06755	COG0833	amino acid
DDV21_RS06765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DDV21_RS06775	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DDV21_RS06785	COG3425	synthase
DDV21_RS06800	COG1272	protein, Hemolysin III
DDV21_RS06805	COG1304	FMN binding
DDV21_RS06830	COG1126	abc transporter atp-binding protein
DDV21_RS06835	COG0765	amino acid transport
DDV21_RS06840	COG0765	amino acid transport
DDV21_RS06845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDV21_RS06855	COG0583	DNA-binding transcription factor activity
DDV21_RS06865	COG0745	RESPONSE REGULATOR receiver
DDV21_RS06870	COG2357	RelA SpoT domain protein
DDV21_RS06900	COG1132	(ABC) transporter
DDV21_RS06915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDV21_RS06930	COG1132	(ABC) transporter
DDV21_RS06945	COG0488	(ABC) transporter
DDV21_RS06955	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DDV21_RS06970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDV21_RS06975	COG0667	Aldo Keto reductase
DDV21_RS06985	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDV21_RS07010	COG0789	Transcriptional regulator
DDV21_RS07015	COG3942	CHAP domain
DDV21_RS07015	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDV21_RS07020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDV21_RS07020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS07020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDV21_RS07025	COG1105	Belongs to the carbohydrate kinase PfkB family
DDV21_RS07030	COG1349	DNA-binding transcription factor activity
DDV21_RS07035	COG0492	ferredoxin-NADP+ reductase activity
DDV21_RS07045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DDV21_RS07055	COG1837	Belongs to the UPF0109 family
DDV21_RS07070	COG0577	efflux transmembrane transporter activity
DDV21_RS07075	COG1136	(ABC) transporter
DDV21_RS07100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDV21_RS07105	COG0505	Belongs to the CarA family
DDV21_RS07110	COG0540	Belongs to the ATCase OTCase family
DDV21_RS07120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DDV21_RS07125	COG0564	pseudouridine synthase activity
DDV21_RS07135	COG0583	DNA-binding transcription factor activity
DDV21_RS07140	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DDV21_RS07180	COG1104	cysteine desulfurase activity
DDV21_RS07200	COG0463	Glycosyl transferase, family 2
DDV21_RS07205	COG0285	dihydrofolate synthase activity
DDV21_RS07210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDV21_RS07220	COG0287	Prephenate dehydrogenase
DDV21_RS07235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DDV21_RS07245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DDV21_RS07250	COG1368	sulfuric ester hydrolase activity
DDV21_RS07255	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DDV21_RS07265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DDV21_RS07270	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DDV21_RS07275	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DDV21_RS07280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DDV21_RS07315	COG0463	Glycosyl transferase, family 2
DDV21_RS07325	COG1368	sulfuric ester hydrolase activity
DDV21_RS07360	COG1091	dTDP-4-dehydrorhamnose reductase activity
DDV21_RS07365	COG2151	metal-sulfur cluster biosynthetic enzyme
DDV21_RS07370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDV21_RS07375	COG0358	DNA primase activity
DDV21_RS07380	COG1970	mechanosensitive ion channel activity
DDV21_RS07410	COG0436	Aminotransferase
DDV21_RS07420	COG0058	SHG alpha-glucan phosphorylase activity
DDV21_RS07425	COG1640	4-alpha-glucanotransferase
DDV21_RS07430	COG1609	Transcriptional regulator
DDV21_RS07440	COG1175	transmembrane transport
DDV21_RS07445	COG3833	ABC-type maltose transport systems, permease component
DDV21_RS07450	COG3842	ATPase activity
DDV21_RS07455	COG0556	nucleotide-excision repair
DDV21_RS07460	COG0765	amino acid transport
DDV21_RS07465	COG1126	abc transporter atp-binding protein
DDV21_RS07470	COG0488	(ABC) transporter
DDV21_RS07495	COG0561	phosphatase activity
DDV21_RS07500	COG1349	DNA-binding transcription factor activity
DDV21_RS07510	COG1063	alcohol dehydrogenase
DDV21_RS07515	COG0561	phosphatase activity
DDV21_RS07535	COG0667	Aldo Keto reductase
DDV21_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
DDV21_RS07580	COG1263	PTS System
DDV21_RS07580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS07585	COG1609	Transcriptional regulator
DDV21_RS07600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDV21_RS07605	COG1316	TRANSCRIPTIONal
DDV21_RS07610	COG0077	Prephenate dehydratase
DDV21_RS07620	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DDV21_RS07625	COG0148	phosphopyruvate hydratase activity
DDV21_RS07660	COG0107	imidazoleglycerol-phosphate synthase activity
DDV21_RS07670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DDV21_RS07680	COG0560	Phosphoserine phosphatase
DDV21_RS07685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DDV21_RS07690	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DDV21_RS07695	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DDV21_RS07735	COG0772	Belongs to the SEDS family
DDV21_RS07755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDV21_RS07780	COG0716	FMN binding
DDV21_RS07785	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDV21_RS07790	COG0625	glutathione transferase activity
DDV21_RS07795	COG2153	protein acetylation
DDV21_RS07800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DDV21_RS07805	COG0254	rRNA binding
DDV21_RS07810	COG4932	domain protein
DDV21_RS07815	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DDV21_RS07820	COG1215	transferase activity, transferring glycosyl groups
DDV21_RS07830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DDV21_RS07855	COG1063	alcohol dehydrogenase
DDV21_RS07880	COG1660	Displays ATPase and GTPase activities
DDV21_RS07885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DDV21_RS07900	COG0438	transferase activity, transferring glycosyl groups
DDV21_RS07920	COG0251	oxidation-reduction process
DDV21_RS07925	COG0017	Asparaginyl-tRNA synthetase
DDV21_RS07930	COG0436	Aminotransferase
DDV21_RS07940	COG1199	ATP-dependent helicase activity
DDV21_RS07940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDV21_RS07955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDV21_RS07970	COG2177	Part of the ABC transporter FtsEX involved in
DDV21_RS07975	COG2884	Cell division ATP-binding protein ftsE
DDV21_RS07985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DDV21_RS07990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDV21_RS08000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DDV21_RS08025	COG1078	dGTPase activity
DDV21_RS08035	COG2348	transferase activity, transferring amino-acyl groups
DDV21_RS08060	COG2274	protein secretion by the type I secretion system
DDV21_RS08080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDV21_RS08085	COG0772	Belongs to the SEDS family
DDV21_RS08095	COG0386	Belongs to the glutathione peroxidase family
DDV21_RS08115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DDV21_RS08130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDV21_RS08135	COG0406	alpha-ribazole phosphatase activity
DDV21_RS08145	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDV21_RS08150	COG1268	BioY protein
DDV21_RS08155	COG4443	Transcriptional Coactivator p15 (PC4)
DDV21_RS08165	COG0826	peptidase U32
DDV21_RS08190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DDV21_RS08195	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DDV21_RS08210	COG2183	response to ionizing radiation
DDV21_RS08215	COG0701	Predicted permease
DDV21_RS08220	COG3689	TIGRFAM TIGR03943 family protein
DDV21_RS08225	COG0552	protein localization to endoplasmic reticulum
DDV21_RS08230	COG0561	phosphatase activity
DDV21_RS08235	COG0561	phosphatase activity
DDV21_RS08240	COG1196	nuclear chromosome segregation
DDV21_RS08245	COG0571	ribonuclease III activity
DDV21_RS08250	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DDV21_RS08255	COG5002	protein histidine kinase activity
DDV21_RS08260	COG0745	RESPONSE REGULATOR receiver
DDV21_RS08270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDV21_RS08275	COG0765	amino acid transport
DDV21_RS08280	COG0765	amino acid transport
DDV21_RS08290	COG0745	RESPONSE REGULATOR receiver
DDV21_RS08300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DDV21_RS08305	COG0438	transferase activity, transferring glycosyl groups
DDV21_RS08320	COG1609	Transcriptional regulator
DDV21_RS08325	COG0006	proline dipeptidase activity
DDV21_RS08330	COG3394	polysaccharide catabolic process
DDV21_RS08340	COG2190	(PTS) system
DDV21_RS08340	COG1263	PTS System
DDV21_RS08340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS08355	COG1811	Na channel or pump
DDV21_RS08360	COG0778	Nitroreductase
DDV21_RS08365	COG0346	lactoylglutathione lyase activity
DDV21_RS08370	COG2723	6-phospho-beta-galactosidase activity
DDV21_RS08375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDV21_RS08375	COG1263	PTS System
DDV21_RS08375	COG2190	(PTS) system
DDV21_RS08380	COG1737	Transcriptional regulator
DDV21_RS08390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDV21_RS08390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDV21_RS08395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDV21_RS08410	COG1846	Transcriptional regulator
DDV21_RS08415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDV21_RS08430	COG0557	exoribonuclease II activity
DDV21_RS08440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDV21_RS08445	COG2814	Major facilitator Superfamily
DDV21_RS08450	COG0237	dephospho-CoA kinase activity
DDV21_RS08455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDV21_RS08470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDV21_RS08475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DDV21_RS08485	COG1573	uracil-dna glycosylase
DDV21_RS08490	COG1702	phosphate starvation-inducible protein PhoH
DDV21_RS08500	COG4479	Belongs to the UPF0346 family
DDV21_RS08510	COG0233	cytoplasmic translational termination
DDV21_RS08520	COG0081	regulation of translation
DDV21_RS08525	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DDV21_RS08540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDV21_RS08545	COG2274	protein secretion by the type I secretion system
DDV21_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
DDV21_RS08675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDV21_RS08675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDV21_RS08685	COG0708	Exodeoxyribonuclease III
DDV21_RS08695	COG1393	Belongs to the ArsC family
DDV21_RS08700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDV21_RS08705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDV21_RS08715	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DDV21_RS08735	COG1774	PSP1 C-terminal conserved region
DDV21_RS08740	COG0470	DNA polymerase III
DDV21_RS08750	COG0517	IMP dehydrogenase activity
DDV21_RS08760	COG1733	regulation of RNA biosynthetic process
DDV21_RS08780	COG0559	Belongs to the binding-protein-dependent transport system permease family
DDV21_RS08800	COG0740	serine-type endopeptidase activity
DDV21_RS08840	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDV21_RS08845	COG0626	cystathionine gamma-synthase activity
DDV21_RS08850	COG2244	polysaccharide biosynthetic process
DDV21_RS08855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DDV21_RS08860	COG1120	ATPase activity
DDV21_RS08865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDV21_RS08870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDV21_RS08905	COG1028	Short-chain dehydrogenase reductase Sdr
DDV21_RS08920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDV21_RS08925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDV21_RS08955	COG2851	Citrate transporter
DDV21_RS08965	COG0710	3-dehydroquinate dehydratase activity
DDV21_RS08970	COG0738	Major facilitator superfamily
DDV21_RS08975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DDV21_RS08980	COG2271	Major facilitator Superfamily
DDV21_RS08985	COG0583	DNA-binding transcription factor activity
DDV21_RS08990	COG1902	pentaerythritol trinitrate reductase activity
DDV21_RS08995	COG0698	ribose 5-phosphate isomerase
DDV21_RS09000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDV21_RS09010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DDV21_RS09015	COG2137	regulation of response to DNA damage stimulus
DDV21_RS09020	COG3557	Belongs to the UPF0374 family
DDV21_RS09085	COG1040	competence protein
DDV21_RS09090	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DDV21_RS09095	COG1739	Uncharacterized protein family UPF0029
DDV21_RS09105	COG0539	negative regulation of cytoplasmic translation
DDV21_RS09115	COG2197	response regulator
DDV21_RS09120	COG4585	Histidine kinase
DDV21_RS09130	COG2815	serine threonine protein kinase
DDV21_RS09130	COG0515	serine threonine protein kinase
DDV21_RS09140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DDV21_RS09140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDV21_RS09150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DDV21_RS09155	COG1758	RNA polymerase activity
DDV21_RS09180	COG1854	S-ribosylhomocysteine lyase activity
DDV21_RS09190	COG0116	Belongs to the methyltransferase superfamily
DDV21_RS09200	COG3599	regulation of cell shape
DDV21_RS09215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDV21_RS09220	COG3579	cysteine-type endopeptidase activity
DDV21_RS09225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DDV21_RS09230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DDV21_RS09250	COG1126	abc transporter atp-binding protein
DDV21_RS09255	COG0765	amino acid transport
DDV21_RS09265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDV21_RS09275	COG0513	Belongs to the DEAD box helicase family
DDV21_RS09280	COG2020	methyltransferase activity
DDV21_RS09290	COG0768	penicillin binding
DDV21_RS09305	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DDV21_RS09320	COG1131	(ABC) transporter
DDV21_RS09330	COG3037	sugar-specific permease SgaT UlaA
DDV21_RS09345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS09355	COG3711	transcriptional antiterminator
DDV21_RS09380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDV21_RS09385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDV21_RS09390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDV21_RS09390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDV21_RS09390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS09395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS09395	COG3711	transcriptional antiterminator
DDV21_RS09405	COG4224	UPF0291 protein
DDV21_RS09460	COG0656	L-ascorbic acid biosynthetic process
DDV21_RS09480	COG0561	phosphatase activity
DDV21_RS09495	COG2723	6-phospho-beta-galactosidase activity
DDV21_RS09500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDV21_RS09500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDV21_RS09505	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDV21_RS09515	COG1105	Belongs to the carbohydrate kinase PfkB family
DDV21_RS09520	COG0698	ribose 5-phosphate isomerase
DDV21_RS09535	COG0076	glutamate decarboxylase activity
DDV21_RS09545	COG2217	Heavy metal translocating P-type atpase
DDV21_RS09560	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DDV21_RS09565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DDV21_RS09575	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DDV21_RS09580	COG0195	Participates in both transcription termination and antitermination
DDV21_RS09600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDV21_RS09610	COG0668	transmembrane transport
DDV21_RS09625	COG0351	phosphomethylpyrimidine kinase
DDV21_RS09655	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDV21_RS09660	COG1876	peptidase activity
DDV21_RS09665	COG0588	phosphoglycerate mutase activity
DDV21_RS09670	COG2848	UPF0210 protein
DDV21_RS09675	COG3830	Belongs to the UPF0237 family
DDV21_RS09695	COG0435	Glutathione S-transferase
DDV21_RS09705	COG0435	Glutathione S-transferase
DDV21_RS09720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDV21_RS09735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDV21_RS09740	COG4608	Belongs to the ABC transporter superfamily
DDV21_RS09745	COG0444	Belongs to the ABC transporter superfamily
DDV21_RS09750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDV21_RS09755	COG0601	transmembrane transport
DDV21_RS09760	COG4166	transmembrane transport
DDV21_RS09765	COG1473	amidohydrolase
DDV21_RS09800	COG0596	Alpha beta hydrolase
DDV21_RS09805	COG4221	oxidoreductase activity
DDV21_RS09805	COG3321	synthase
DDV21_RS09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDV21_RS09805	COG0604	alcohol dehydrogenase
DDV21_RS09820	COG4608	Belongs to the ABC transporter superfamily
DDV21_RS09825	COG0444	Belongs to the ABC transporter superfamily
DDV21_RS09830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDV21_RS09835	COG0601	transmembrane transport
DDV21_RS09840	COG4166	transmembrane transport
DDV21_RS09845	COG1686	Belongs to the peptidase S11 family
DDV21_RS09855	COG0719	Fe-S assembly protein
DDV21_RS09865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDV21_RS09870	COG0719	Fe-S assembly protein
DDV21_RS09880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DDV21_RS09900	COG0765	amino acid transport
DDV21_RS09905	COG1126	abc transporter atp-binding protein
DDV21_RS09925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDV21_RS09955	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DDV21_RS09960	COG0440	acetolactate synthase activity
DDV21_RS09965	COG0028	Belongs to the TPP enzyme family
DDV21_RS09970	COG1461	Dihydroxyacetone kinase
DDV21_RS09980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDV21_RS09985	COG2378	regulation of single-species biofilm formation
DDV21_RS10040	COG1131	(ABC) transporter
DDV21_RS10130	COG4499	WXG100 protein secretion system (Wss), protein YukC
DDV21_RS10410	COG4974	Belongs to the 'phage' integrase family
DDV21_RS10420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DDV21_RS10430	COG4473	ABC transporter
DDV21_RS10435	COG1131	(ABC) transporter
DDV21_RS10440	COG0537	adenosine 5'-monophosphoramidase activity
DDV21_RS10450	COG1316	TRANSCRIPTIONal
DDV21_RS10460	COG0802	atpase or kinase
DDV21_RS10465	COG2252	PERMEase
DDV21_RS10475	COG0561	phosphatase activity
DDV21_RS10485	COG3715	PTS system
DDV21_RS10490	COG3716	PTS system mannose fructose sorbose family IID component
DDV21_RS10510	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DDV21_RS10530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DDV21_RS10535	COG0439	Biotin carboxylase
DDV21_RS10540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDV21_RS10550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDV21_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
DDV21_RS10560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DDV21_RS10565	COG2070	2-Nitropropane dioxygenase
DDV21_RS10575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDV21_RS10585	COG1024	Enoyl-CoA hydratase
DDV21_RS10590	COG0527	aspartate kinase activity
DDV21_RS10670	COG0789	Transcriptional regulator
DDV21_RS10670	COG4978	Transcriptional regulator
DDV21_RS10730	COG0582	viral genome integration into host DNA
DDV21_RS10735	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DDV21_RS10740	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DDV21_RS10745	COG0071	Belongs to the small heat shock protein (HSP20) family
DDV21_RS10770	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DDV21_RS10785	COG1045	serine acetyltransferase
DDV21_RS10795	COG1185	polyribonucleotide nucleotidyltransferase activity
DDV21_RS10800	COG1012	belongs to the aldehyde dehydrogenase family
DDV21_RS10800	COG1454	alcohol dehydrogenase
DDV21_RS10810	COG0242	peptide deformylase activity
DDV21_RS10825	COG1846	Transcriptional regulator
DDV21_RS10830	COG2176	DNA-directed DNA polymerase activity
DDV21_RS10840	COG0442	prolyl-tRNA aminoacylation
DDV21_RS10850	COG4589	Belongs to the CDS family
DDV21_RS10855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDV21_RS10865	COG1862	Preprotein translocase
DDV21_RS10880	COG4932	domain protein
DDV21_RS10880	COG4932	domain protein
DDV21_RS10990	COG0343	queuine tRNA-ribosyltransferase activity
DDV21_RS11000	COG1832	CoA-binding protein
DDV21_RS11010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDV21_RS11010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDV21_RS11015	COG1396	sequence-specific DNA binding
DDV21_RS11035	COG3448	diguanylate cyclase activity
DDV21_RS11035	COG4175	Glycine betaine
DDV21_RS11045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DDV21_RS11055	COG3711	transcriptional antiterminator
DDV21_RS11055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS11065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDV21_RS11110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS11120	COG3037	sugar-specific permease SgaT UlaA
DDV21_RS11125	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DDV21_RS11135	COG3775	system Galactitol-specific IIC component
DDV21_RS11140	COG3414	Phosphotransferase system galactitol-specific IIB component
DDV21_RS11150	COG3711	transcriptional antiterminator
DDV21_RS11150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDV21_RS11160	COG2918	glutathione biosynthetic process
DDV21_RS11160	COG1181	Belongs to the D-alanine--D-alanine ligase family
DDV21_RS11185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDV21_RS11190	COG3942	CHAP domain
DDV21_RS11190	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDV21_RS11200	COG4932	domain protein
DDV21_RS11210	COG4932	domain protein
DDV21_RS11210	COG1388	LysM domain
DDV21_RS11215	COG0549	Belongs to the carbamate kinase family
DDV21_RS11220	COG2957	Belongs to the agmatine deiminase family
DDV21_RS11225	COG0531	amino acid
DDV21_RS11230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDV21_RS11235	COG2197	response regulator
DDV21_RS11245	COG0602	queuosine metabolic process
DDV21_RS11260	COG1328	CTP reductase activity
DDV21_RS11275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DDV21_RS11280	COG4472	Bacterial protein of unknown function (DUF965)
DDV21_RS11295	COG1393	Belongs to the ArsC family
DDV21_RS11300	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DDV21_RS11305	COG1546	Belongs to the CinA family
DDV21_RS11305	COG1058	Belongs to the CinA family
DDV21_RS11310	COG0519	Catalyzes the synthesis of GMP from XMP
DDV21_RS11315	COG0632	four-way junction helicase activity
DDV21_RS11325	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DDV21_RS11330	COG4550	Control of competence regulator ComK, YlbF/YmcA
DDV21_RS11340	COG0018	arginyl-trna synthetase
DDV21_RS11355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDV21_RS11360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDV21_RS11380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DDV21_RS11385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDV21_RS11405	COG5290	Psort location Cytoplasmic, score
DDV21_RS11440	COG0300	oxidoreductase activity
DDV21_RS11445	COG1070	Carbohydrate kinase
DDV21_RS11450	COG0191	fructose-bisphosphate aldolase activity
DDV21_RS11465	COG3732	PTS system glucitol sorbitol-specific
DDV21_RS11470	COG3730	PTS system glucitol sorbitol-specific
DDV21_RS11480	COG2188	Transcriptional regulator
DDV21_RS11495	COG0640	Transcriptional regulator
DDV21_RS11520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DDV21_RS11530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DDV21_RS11535	COG3759	membrane
DDV21_RS11540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DDV21_RS11550	COG0305	Participates in initiation and elongation during chromosome replication
DDV21_RS11565	COG0445	tRNA wobble uridine modification
DDV21_RS11580	COG0741	lytic transglycosylase activity
DDV21_RS11600	COG1122	ATPase activity
DDV21_RS11615	COG0612	Peptidase, M16
DDV21_RS11620	COG0612	Peptidase, M16
DDV21_RS11640	COG0517	IMP dehydrogenase activity
DDV21_RS11640	COG0516	GMP reductase activity
DDV21_RS11650	COG0488	(ABC) transporter
DDV21_RS11685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDV21_RS11690	COG1475	DNA binding