locus-tag	class	description
AXE83_RS00015	COG0531	amino acid
AXE83_RS00025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXE83_RS00025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AXE83_RS00030	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXE83_RS00030	COG1388	LysM domain
AXE83_RS00040	COG0305	Participates in initiation and elongation during chromosome replication
AXE83_RS00060	COG1040	competence protein
AXE83_RS00065	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AXE83_RS00070	COG1739	Uncharacterized protein family UPF0029
AXE83_RS00085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AXE83_RS00100	COG3942	CHAP domain
AXE83_RS00110	COG1792	Involved in formation and maintenance of cell shape
AXE83_RS00115	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AXE83_RS00120	COG1122	ATPase activity
AXE83_RS00125	COG1122	ATPase activity
AXE83_RS00130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXE83_RS00140	COG0612	Peptidase, M16
AXE83_RS00145	COG0612	Peptidase, M16
AXE83_RS00150	COG2501	S4 domain
AXE83_RS00160	COG0516	GMP reductase activity
AXE83_RS00160	COG0517	IMP dehydrogenase activity
AXE83_RS00165	COG0180	Tryptophanyl-tRNA synthetase
AXE83_RS00170	COG0488	(ABC) transporter
AXE83_RS00180	COG1511	domain protein
AXE83_RS00180	COG1511	domain protein
AXE83_RS00215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXE83_RS00220	COG1475	DNA binding
AXE83_RS00230	COG0592	DNA-directed DNA polymerase activity
AXE83_RS00240	COG0012	GTP binding
AXE83_RS00250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXE83_RS00255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AXE83_RS00280	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AXE83_RS00285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXE83_RS00350	COG0582	viral genome integration into host DNA
AXE83_RS00485	COG3728	DNA packaging
AXE83_RS00485	COG5484	DNA packaging
AXE83_RS00610	COG5632	N-Acetylmuramoyl-L-alanine amidase
AXE83_RS00610	COG5263	repeat protein
AXE83_RS00615	COG0756	dUTP diphosphatase activity
AXE83_RS00635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AXE83_RS00650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXE83_RS00660	COG4509	Sortase family
AXE83_RS00665	COG1832	CoA-binding protein
AXE83_RS00670	COG2855	membrane
AXE83_RS00685	COG0436	Aminotransferase
AXE83_RS00700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXE83_RS00740	COG2274	protein secretion by the type I secretion system
AXE83_RS00745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXE83_RS00755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AXE83_RS00760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AXE83_RS00770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXE83_RS00775	COG0138	bifunctional purine biosynthesis protein purh
AXE83_RS00795	COG0151	Belongs to the GarS family
AXE83_RS00800	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AXE83_RS00805	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXE83_RS00815	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXE83_RS00820	COG3583	domain protein
AXE83_RS00820	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AXE83_RS00820	COG3064	Membrane
AXE83_RS00835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXE83_RS00840	COG3715	PTS system
AXE83_RS00845	COG3716	PTS system mannose fructose sorbose family IID component
AXE83_RS00855	COG2222	sugar isomerase
AXE83_RS00860	COG3684	Belongs to the aldolase LacD family
AXE83_RS00875	COG1216	Glycosyl transferase, family 2
AXE83_RS00875	COG1442	glycosyl transferase family 8
AXE83_RS00890	COG1442	glycosyl transferase family 8
AXE83_RS00900	COG0438	transferase activity, transferring glycosyl groups
AXE83_RS00905	COG1442	glycosyl transferase family 8
AXE83_RS00910	COG1216	Glycosyl transferase, family 2
AXE83_RS00910	COG1442	glycosyl transferase family 8
AXE83_RS00940	COG1214	PFAM Peptidase M22, glycoprotease
AXE83_RS00955	COG1396	sequence-specific DNA binding
AXE83_RS00990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXE83_RS00995	COG1464	Belongs to the NlpA lipoprotein family
AXE83_RS01000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXE83_RS01005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXE83_RS01030	COG0124	histidyl-tRNA synthetase
AXE83_RS01040	COG1476	TRANSCRIPTIONal
AXE83_RS01085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXE83_RS01090	COG1609	Transcriptional regulator
AXE83_RS01095	COG5521	maltodextrose utilization protein MalA
AXE83_RS01100	COG3833	ABC-type maltose transport systems, permease component
AXE83_RS01105	COG1175	transmembrane transport
AXE83_RS01110	COG2182	Extracellular solute-binding protein
AXE83_RS01115	COG1640	4-alpha-glucanotransferase
AXE83_RS01120	COG0058	SHG alpha-glucan phosphorylase activity
AXE83_RS01130	COG2226	methyltransferase
AXE83_RS01140	COG2217	Heavy metal translocating P-type atpase
AXE83_RS01160	COG0519	Catalyzes the synthesis of GMP from XMP
AXE83_RS01190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXE83_RS01195	COG0006	proline dipeptidase activity
AXE83_RS01205	COG1393	Belongs to the ArsC family
AXE83_RS01230	COG0285	dihydrofolate synthase activity
AXE83_RS01240	COG0561	phosphatase activity
AXE83_RS01245	COG2252	PERMEase
AXE83_RS01250	COG0802	atpase or kinase
AXE83_RS01260	COG1316	TRANSCRIPTIONal
AXE83_RS01290	COG0534	Mate efflux family protein
AXE83_RS01340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AXE83_RS01350	COG1461	Dihydroxyacetone kinase
AXE83_RS01365	COG1131	(ABC) transporter
AXE83_RS01375	COG4585	Histidine kinase
AXE83_RS01380	COG2197	response regulator
AXE83_RS01385	COG0494	nUDIX hydrolase
AXE83_RS01395	COG0525	valine-tRNA ligase activity
AXE83_RS01405	COG0519	Catalyzes the synthesis of GMP from XMP
AXE83_RS01420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXE83_RS01425	COG4589	Belongs to the CDS family
AXE83_RS01430	COG0750	zinc metalloprotease
AXE83_RS01440	COG2723	6-phospho-beta-galactosidase activity
AXE83_RS01450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXE83_RS01465	COG0697	spore germination
AXE83_RS01470	COG4499	WXG100 protein secretion system (Wss), protein YukC
AXE83_RS01470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXE83_RS01475	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AXE83_RS01485	COG1178	ABC-type Fe3 transport system permease component
AXE83_RS01490	COG3842	ATPase activity
AXE83_RS01495	COG1840	ABC-type Fe3 transport system, periplasmic component
AXE83_RS01505	COG2972	Histidine kinase
AXE83_RS01535	COG2255	four-way junction helicase activity
AXE83_RS01570	COG0438	transferase activity, transferring glycosyl groups
AXE83_RS01575	COG1442	glycosyl transferase family 8
AXE83_RS01580	COG1442	glycosyl transferase family 8
AXE83_RS01585	COG1442	glycosyl transferase family 8
AXE83_RS01590	COG0201	protein transport
AXE83_RS01610	COG0653	protein targeting
AXE83_RS01615	COG0438	transferase activity, transferring glycosyl groups
AXE83_RS01620	COG0438	transferase activity, transferring glycosyl groups
AXE83_RS01630	COG1187	pseudouridine synthase activity
AXE83_RS01640	COG3579	cysteine-type endopeptidase activity
AXE83_RS01665	COG3716	PTS system mannose fructose sorbose family IID component
AXE83_RS01670	COG3715	PTS system
AXE83_RS01680	COG1064	alcohol dehydrogenase
AXE83_RS01695	COG0534	Mate efflux family protein
AXE83_RS01700	COG0546	phosphoglycolate phosphatase activity
AXE83_RS01720	COG3759	membrane
AXE83_RS01740	COG2151	metal-sulfur cluster biosynthetic enzyme
AXE83_RS01770	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXE83_RS01805	COG3237	CsbD-like
AXE83_RS01815	COG2972	Histidine kinase
AXE83_RS01820	COG4753	response regulator
AXE83_RS01820	COG2207	Transcriptional regulator
AXE83_RS01830	COG1780	Probably involved in ribonucleotide reductase function
AXE83_RS01850	COG1438	arginine binding
AXE83_RS01885	COG2176	DNA-directed DNA polymerase activity
AXE83_RS01900	COG2309	aminopeptidase activity
AXE83_RS01935	COG1609	Transcriptional regulator
AXE83_RS01940	COG4209	transmembrane transport
AXE83_RS01945	COG0395	ABC-type sugar transport system, permease component
AXE83_RS01950	COG1653	transport
AXE83_RS01955	COG1621	beta-fructofuranosidase activity
AXE83_RS01965	COG0596	Alpha beta hydrolase
AXE83_RS01970	COG0604	alcohol dehydrogenase
AXE83_RS01970	COG1028	Short-chain dehydrogenase reductase Sdr
AXE83_RS01970	COG3321	synthase
AXE83_RS01985	COG0628	permease
AXE83_RS02000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXE83_RS02020	COG1051	belongs to the nudix hydrolase family
AXE83_RS02030	COG2264	protein methyltransferase activity
AXE83_RS02035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXE83_RS02040	COG1164	Oligoendopeptidase f
AXE83_RS02060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXE83_RS02075	COG0720	synthase
AXE83_RS02085	COG3118	belongs to the thioredoxin family
AXE83_RS02105	COG1346	cytolysis
AXE83_RS02115	COG1131	(ABC) transporter
AXE83_RS02120	COG1725	Transcriptional regulator
AXE83_RS02135	COG1484	DNA-dependent DNA replication
AXE83_RS02150	COG2963	transposase activity
AXE83_RS02155	COG2801	Transposase and inactivated derivatives
AXE83_RS02175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AXE83_RS02185	COG0517	IMP dehydrogenase activity
AXE83_RS02205	COG1187	pseudouridine synthase activity
AXE83_RS02215	COG1363	Peptidase, m42
AXE83_RS02230	COG3064	Membrane
AXE83_RS02230	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AXE83_RS02230	COG3583	domain protein
AXE83_RS02235	COG0126	phosphoglycerate kinase activity
AXE83_RS02240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXE83_RS02245	COG0285	dihydrofolate synthase activity
AXE83_RS02255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AXE83_RS02255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AXE83_RS02270	COG1609	Transcriptional regulator
AXE83_RS02275	COG0252	asparaginase activity
AXE83_RS02280	COG0561	phosphatase activity
AXE83_RS02285	COG0589	response to stress
AXE83_RS02295	COG1959	2 iron, 2 sulfur cluster binding
AXE83_RS02300	COG3711	transcriptional antiterminator
AXE83_RS02320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXE83_RS02320	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AXE83_RS02340	COG2348	transferase activity, transferring amino-acyl groups
AXE83_RS02355	COG0322	excinuclease ABC activity
AXE83_RS02365	COG4839	cell division protein FtsL
AXE83_RS02370	COG0768	penicillin binding
AXE83_RS02385	COG0789	Transcriptional regulator
AXE83_RS02390	COG0174	glutamine synthetase
AXE83_RS02415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AXE83_RS02430	COG0484	heat shock protein binding
AXE83_RS02445	COG0537	adenosine 5'-monophosphoramidase activity
AXE83_RS02450	COG1131	(ABC) transporter
AXE83_RS02475	COG3290	protein histidine kinase activity
AXE83_RS02515	COG1266	CAAX protease self-immunity
AXE83_RS02535	COG0195	Participates in both transcription termination and antitermination
AXE83_RS02540	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AXE83_RS02590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXE83_RS02595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXE83_RS02600	COG4221	oxidoreductase activity
AXE83_RS02630	COG0527	aspartate kinase activity
AXE83_RS02640	COG1024	Enoyl-CoA hydratase
AXE83_RS02645	COG1846	Transcriptional regulator
AXE83_RS02655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXE83_RS02665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXE83_RS02670	COG1028	Short-chain dehydrogenase reductase Sdr
AXE83_RS02675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXE83_RS02690	COG0439	Biotin carboxylase
AXE83_RS02695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AXE83_RS02760	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXE83_RS02765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AXE83_RS02770	COG1288	antiporter activity
AXE83_RS02780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AXE83_RS02785	COG2235	arginine
AXE83_RS02810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXE83_RS02815	COG0569	domain protein
AXE83_RS02825	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AXE83_RS02830	COG0671	phosphoesterase, PA-phosphatase related
AXE83_RS02850	COG0081	regulation of translation
AXE83_RS02855	COG0028	Belongs to the TPP enzyme family
AXE83_RS02860	COG0440	acetolactate synthase activity
AXE83_RS02870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXE83_RS02885	COG1126	abc transporter atp-binding protein
AXE83_RS02890	COG0765	amino acid transport
AXE83_RS02905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXE83_RS02910	COG1882	Formate acetyltransferase
AXE83_RS02925	COG4166	transmembrane transport
AXE83_RS02930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXE83_RS02955	COG0116	Belongs to the methyltransferase superfamily
AXE83_RS02965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AXE83_RS02970	COG0745	RESPONSE REGULATOR receiver
AXE83_RS02980	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AXE83_RS03005	COG4585	Histidine kinase
AXE83_RS03010	COG2197	response regulator
AXE83_RS03020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXE83_RS03025	COG0681	Belongs to the peptidase S26 family
AXE83_RS03050	COG1115	amino acid carrier protein
AXE83_RS03055	COG2211	Major facilitator Superfamily
AXE83_RS03110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXE83_RS03130	COG1573	uracil-dna glycosylase
AXE83_RS03135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AXE83_RS03135	COG0425	Belongs to the sulfur carrier protein TusA family
AXE83_RS03145	COG4808	Protein conserved in bacteria
AXE83_RS03150	COG1363	Peptidase, m42
AXE83_RS03175	COG0456	acetyltransferase
AXE83_RS03180	COG0072	phenylalanine-tRNA ligase activity
AXE83_RS03180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXE83_RS03190	COG4152	abc transporter atp-binding protein
AXE83_RS03195	COG1668	transmembrane transport
AXE83_RS03205	COG0504	CTP synthase activity
AXE83_RS03245	COG0436	Aminotransferase
AXE83_RS03250	COG0017	Asparaginyl-tRNA synthetase
AXE83_RS03275	COG3231	kanamycin kinase activity
AXE83_RS03280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXE83_RS03285	COG0149	triose-phosphate isomerase activity
AXE83_RS03305	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AXE83_RS03325	COG0251	oxidation-reduction process
AXE83_RS03335	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AXE83_RS03345	COG0492	ferredoxin-NADP+ reductase activity
AXE83_RS03350	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AXE83_RS03370	COG1307	EDD domain protein, DegV family
AXE83_RS03380	COG0617	tRNA 3'-terminal CCA addition
AXE83_RS03385	COG0488	(ABC) transporter
AXE83_RS03395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXE83_RS03405	COG3935	DnaD domain protein
AXE83_RS03415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AXE83_RS03440	COG0287	Prephenate dehydrogenase
AXE83_RS03445	COG3679	Belongs to the UPF0342 family
AXE83_RS03460	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AXE83_RS03465	COG0077	Prephenate dehydratase
AXE83_RS03475	COG3475	LICD family
AXE83_RS03480	COG1442	glycosyl transferase family 8
AXE83_RS03480	COG1216	Glycosyl transferase, family 2
AXE83_RS03485	COG3475	LICD family
AXE83_RS03500	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AXE83_RS03505	COG2884	Cell division ATP-binding protein ftsE
AXE83_RS03510	COG2177	Part of the ABC transporter FtsEX involved in
AXE83_RS03540	COG0433	COG0433 Predicted ATPase
AXE83_RS03580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AXE83_RS03595	COG1045	serine acetyltransferase
AXE83_RS03610	COG0215	cysteine-tRNA ligase activity
AXE83_RS03615	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AXE83_RS03625	COG3842	ATPase activity
AXE83_RS03645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AXE83_RS03665	COG3590	peptidase
AXE83_RS03680	COG0745	RESPONSE REGULATOR receiver
AXE83_RS03685	COG2205	protein histidine kinase activity
AXE83_RS03690	COG1136	(ABC) transporter
AXE83_RS03695	COG0577	efflux transmembrane transporter activity
AXE83_RS03705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AXE83_RS03725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXE83_RS03730	COG1120	ATPase activity
AXE83_RS03740	COG2819	hydrolase of the alpha beta superfamily
AXE83_RS03745	COG0513	Belongs to the DEAD box helicase family
AXE83_RS03770	COG1136	(ABC) transporter
AXE83_RS03780	COG2188	Transcriptional regulator
AXE83_RS03810	COG0542	response to heat
AXE83_RS03815	COG4703	Protein of unknown function (DUF1797)
AXE83_RS03820	COG0765	amino acid transport
AXE83_RS03825	COG1126	abc transporter atp-binding protein
AXE83_RS03830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AXE83_RS03835	COG3250	beta-galactosidase activity
AXE83_RS03845	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXE83_RS03855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXE83_RS03855	COG1199	ATP-dependent helicase activity
AXE83_RS03860	COG0772	Belongs to the SEDS family
AXE83_RS03865	COG0693	protein deglycase activity
AXE83_RS03875	COG0187	DNA topoisomerase II activity
AXE83_RS03885	COG0726	polysaccharide deacetylase
AXE83_RS03895	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AXE83_RS03900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AXE83_RS03925	COG0469	pyruvate kinase activity
AXE83_RS03935	COG0204	Acyl-transferase
AXE83_RS03940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXE83_RS03945	COG2384	SAM-dependent methyltransferase
AXE83_RS03950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXE83_RS03955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXE83_RS03960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXE83_RS03965	COG0463	Glycosyl transferase, family 2
AXE83_RS03980	COG2824	Alkylphosphonate utilization operon protein PhnA
AXE83_RS03995	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AXE83_RS04000	COG1272	protein, Hemolysin III
AXE83_RS04015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXE83_RS04020	COG1393	Belongs to the ArsC family
AXE83_RS04030	COG1126	abc transporter atp-binding protein
AXE83_RS04040	COG0492	ferredoxin-NADP+ reductase activity
AXE83_RS04065	COG0561	phosphatase activity
AXE83_RS04090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AXE83_RS04115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXE83_RS04125	COG0647	UMP catabolic process
AXE83_RS04135	COG1393	Belongs to the ArsC family
AXE83_RS04145	COG0483	inositol monophosphate 1-phosphatase activity
AXE83_RS04150	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AXE83_RS04150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXE83_RS04155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXE83_RS04160	COG0573	inorganic phosphate transmembrane transporter activity
AXE83_RS04165	COG0581	inorganic phosphate transmembrane transporter activity
AXE83_RS04170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXE83_RS04175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXE83_RS04180	COG0704	Plays a role in the regulation of phosphate uptake
AXE83_RS04190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXE83_RS04195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXE83_RS04205	COG3527	Alpha-acetolactate decarboxylase
AXE83_RS04220	COG3842	ATPase activity
AXE83_RS04225	COG1177	transmembrane transport
AXE83_RS04250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AXE83_RS04265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXE83_RS04270	COG0167	dihydroorotate dehydrogenase activity
AXE83_RS04280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXE83_RS04285	COG0583	DNA-binding transcription factor activity
AXE83_RS04290	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AXE83_RS04295	COG0564	pseudouridine synthase activity
AXE83_RS04305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXE83_RS04325	COG1196	nuclear chromosome segregation
AXE83_RS04330	COG2860	membrane
AXE83_RS04340	COG1051	belongs to the nudix hydrolase family
AXE83_RS04345	COG0561	phosphatase activity
AXE83_RS04350	COG0561	phosphatase activity
AXE83_RS04355	COG0552	protein localization to endoplasmic reticulum
AXE83_RS04360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AXE83_RS04365	COG1126	abc transporter atp-binding protein
AXE83_RS04370	COG0765	amino acid transport
AXE83_RS04415	COG1827	regulation of RNA biosynthetic process
AXE83_RS04425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AXE83_RS04430	COG0222	ribosome binding
AXE83_RS04440	COG0270	DNA (cytosine-5-)-methyltransferase activity
AXE83_RS04525	COG1136	(ABC) transporter
AXE83_RS04595	COG1396	sequence-specific DNA binding
AXE83_RS04600	COG0542	response to heat
AXE83_RS04620	COG3843	relaxase mobilization nuclease domain protein
AXE83_RS04630	COG2801	Transposase and inactivated derivatives
AXE83_RS04700	COG4974	Belongs to the 'phage' integrase family
AXE83_RS04720	COG4224	UPF0291 protein
AXE83_RS04725	COG0431	NADPH-dependent FMN reductase
AXE83_RS04725	COG1053	succinate dehydrogenase
AXE83_RS04725	COG3976	FMN-binding domain protein
AXE83_RS04745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AXE83_RS04750	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AXE83_RS04760	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AXE83_RS04770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AXE83_RS04775	COG0237	dephospho-CoA kinase activity
AXE83_RS04780	COG2814	Major facilitator Superfamily
AXE83_RS04785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXE83_RS04795	COG0557	exoribonuclease II activity
AXE83_RS04805	COG3615	Tellurite resistance protein tehB
AXE83_RS04805	COG0500	methyltransferase
AXE83_RS04825	COG4122	O-methyltransferase activity
AXE83_RS04840	COG0772	Belongs to the SEDS family
AXE83_RS04845	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AXE83_RS04870	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AXE83_RS04880	COG0358	DNA primase activity
AXE83_RS04885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AXE83_RS04890	COG2151	metal-sulfur cluster biosynthetic enzyme
AXE83_RS04895	COG0438	transferase activity, transferring glycosyl groups
AXE83_RS04900	COG0438	transferase activity, transferring glycosyl groups
AXE83_RS04905	COG1983	PspC domain protein
AXE83_RS04915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXE83_RS04925	COG1438	arginine binding
AXE83_RS04935	COG1194	a g-specific adenine glycosylase
AXE83_RS04940	COG0745	RESPONSE REGULATOR receiver
AXE83_RS04945	COG5002	protein histidine kinase activity
AXE83_RS04950	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AXE83_RS04960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXE83_RS04965	COG0488	(ABC) transporter
AXE83_RS04985	COG1970	mechanosensitive ion channel activity
AXE83_RS04995	COG4708	membrane
AXE83_RS05035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXE83_RS05050	COG0584	glycerophosphoryl diester phosphodiesterase
AXE83_RS05065	COG1063	alcohol dehydrogenase
AXE83_RS05080	COG4750	Nucleotidyl transferase
AXE83_RS05085	COG0543	2 iron, 2 sulfur cluster binding
AXE83_RS05090	COG0167	dihydroorotate dehydrogenase activity
AXE83_RS05095	COG0196	riboflavin kinase activity
AXE83_RS05140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXE83_RS05145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXE83_RS05150	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXE83_RS05155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXE83_RS05170	COG4684	Psort location CytoplasmicMembrane, score
AXE83_RS05175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXE83_RS05180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXE83_RS05210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXE83_RS05225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AXE83_RS05230	COG0494	nUDIX hydrolase
AXE83_RS05240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXE83_RS05245	COG0210	DNA helicase
AXE83_RS05255	COG0745	RESPONSE REGULATOR receiver
AXE83_RS05260	COG2205	protein histidine kinase activity
AXE83_RS05275	COG0561	phosphatase activity
AXE83_RS05320	COG5263	repeat protein
AXE83_RS05320	COG4193	domain, Protein
AXE83_RS05330	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AXE83_RS05385	COG1131	(ABC) transporter
AXE83_RS05390	COG1132	(ABC) transporter
AXE83_RS05405	COG0488	(ABC) transporter
AXE83_RS05470	COG0095	Lipoate-protein ligase
AXE83_RS05475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXE83_RS05480	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXE83_RS05485	COG0022	dehydrogenase e1 component
AXE83_RS05490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXE83_RS05495	COG0534	Mate efflux family protein
AXE83_RS05505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AXE83_RS05510	COG1051	belongs to the nudix hydrolase family
AXE83_RS05530	COG1011	Hydrolase
AXE83_RS05535	COG0280	phosphate acetyltransferase
AXE83_RS05540	COG0564	pseudouridine synthase activity
AXE83_RS05550	COG2357	RelA SpoT domain protein
AXE83_RS05560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXE83_RS05565	COG1104	cysteine desulfurase activity
AXE83_RS05585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AXE83_RS05610	COG1136	(ABC) transporter
AXE83_RS05625	COG2183	response to ionizing radiation
AXE83_RS05635	COG0701	Predicted permease
AXE83_RS05640	COG3689	TIGRFAM TIGR03943 family protein
AXE83_RS05655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXE83_RS05675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AXE83_RS05680	COG1982	Orn Lys Arg decarboxylase major
AXE83_RS05715	COG3196	Protein conserved in bacteria
AXE83_RS05755	COG1597	lipid kinase activity
AXE83_RS05830	COG0789	Transcriptional regulator
AXE83_RS05835	COG1131	(ABC) transporter
AXE83_RS05855	COG0842	Transport permease protein
AXE83_RS05855	COG1129	ABC transporter
AXE83_RS05860	COG1725	Transcriptional regulator
AXE83_RS05880	COG0510	thiamine kinase activity
AXE83_RS05900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AXE83_RS05910	COG0741	lytic transglycosylase activity
AXE83_RS05935	COG2890	protein-(glutamine-N5) methyltransferase activity
AXE83_RS05940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AXE83_RS05950	COG1435	thymidine kinase activity
AXE83_RS05955	COG1942	4-Oxalocrotonate Tautomerase
AXE83_RS05960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AXE83_RS05965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AXE83_RS05970	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXE83_RS05980	COG0803	Belongs to the bacterial solute-binding protein 9 family
AXE83_RS06005	COG3711	transcriptional antiterminator
AXE83_RS06010	COG3684	Belongs to the aldolase LacD family
AXE83_RS06035	COG3775	system Galactitol-specific IIC component
AXE83_RS06060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXE83_RS06065	COG0497	DNA recombination
AXE83_RS06070	COG1438	arginine binding
AXE83_RS06075	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AXE83_RS06115	COG0560	Phosphoserine phosphatase
AXE83_RS06130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AXE83_RS06140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AXE83_RS06150	COG1523	belongs to the glycosyl hydrolase 13 family
AXE83_RS06155	COG1597	lipid kinase activity
AXE83_RS06165	COG2233	PERMEase
AXE83_RS06210	COG0473	3-isopropylmalate dehydrogenase activity
AXE83_RS06225	COG3142	Participates in the control of copper homeostasis
AXE83_RS06230	COG2832	Protein of unknown function (DUF454)
AXE83_RS06235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AXE83_RS06240	COG0758	DNA mediated transformation
AXE83_RS06250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AXE83_RS06255	COG3764	Sortase (surface protein transpeptidase)
AXE83_RS06260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXE83_RS06265	COG0039	L-malate dehydrogenase activity
AXE83_RS06270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXE83_RS06275	COG0785	Cytochrome C biogenesis protein
AXE83_RS06280	COG0024	Methionine aminopeptidase
AXE83_RS06285	COG4109	DRTGG domain
AXE83_RS06295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXE83_RS06305	COG3064	Membrane
AXE83_RS06310	COG3583	domain protein
AXE83_RS06310	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AXE83_RS06335	COG0673	inositol 2-dehydrogenase activity
AXE83_RS06350	COG1078	dGTPase activity
AXE83_RS06380	COG0745	RESPONSE REGULATOR receiver
AXE83_RS06385	COG2205	protein histidine kinase activity
AXE83_RS06430	COG1131	(ABC) transporter
AXE83_RS06445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXE83_RS06450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AXE83_RS06455	COG1605	Chorismate mutase
AXE83_RS06455	COG0077	Prephenate dehydratase
AXE83_RS06460	COG0716	FMN binding
AXE83_RS06465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXE83_RS06480	COG0393	Putative heavy-metal-binding
AXE83_RS06485	COG0776	regulation of translation
AXE83_RS06490	COG1307	EDD domain protein, DegV family
AXE83_RS06500	COG0628	permease
AXE83_RS06505	COG2706	6-phosphogluconolactonase activity
AXE83_RS06535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AXE83_RS06540	COG0356	it plays a direct role in the translocation of protons across the membrane
AXE83_RS06555	COG0826	peptidase U32
AXE83_RS06565	COG1596	polysaccharide export
AXE83_RS06565	COG1555	photosystem II stabilization
AXE83_RS06570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AXE83_RS06575	COG0686	Belongs to the AlaDH PNT family
AXE83_RS06580	COG1404	Belongs to the peptidase S8 family
AXE83_RS06595	COG1702	phosphate starvation-inducible protein PhoH
AXE83_RS06605	COG2996	Protein conserved in bacteria
AXE83_RS06615	COG0528	UMP kinase activity
AXE83_RS06635	COG0470	DNA polymerase III
AXE83_RS06645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AXE83_RS06650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AXE83_RS06665	COG0628	permease
AXE83_RS06670	COG1686	Belongs to the peptidase S11 family
AXE83_RS06745	COG0719	Fe-S assembly protein
AXE83_RS06755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXE83_RS06760	COG0719	Fe-S assembly protein
AXE83_RS06775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXE83_RS06780	COG1956	GAF domain-containing protein
AXE83_RS06785	COG0539	negative regulation of cytoplasmic translation
AXE83_RS06820	COG4166	transmembrane transport
AXE83_RS06825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXE83_RS06830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AXE83_RS06850	COG0187	DNA topoisomerase II activity
AXE83_RS06860	COG1126	abc transporter atp-binding protein
AXE83_RS06865	COG0765	amino acid transport
AXE83_RS06875	COG1079	Belongs to the binding-protein-dependent transport system permease family
AXE83_RS06880	COG4603	Belongs to the binding-protein-dependent transport system permease family
AXE83_RS06885	COG3845	ABC transporter
AXE83_RS06890	COG1744	ABC transporter substrate-binding protein PnrA-like
AXE83_RS06895	COG0295	cytidine deaminase activity
AXE83_RS06905	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AXE83_RS06910	COG2813	Specifically methylates the guanine in position
AXE83_RS06935	COG1763	Mo-molybdopterin cofactor biosynthetic process
AXE83_RS06945	COG0813	purine-nucleoside phosphorylase activity
AXE83_RS06955	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AXE83_RS06980	COG1136	(ABC) transporter
AXE83_RS06995	COG5002	protein histidine kinase activity
AXE83_RS07000	COG0745	RESPONSE REGULATOR receiver
AXE83_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
AXE83_RS07065	COG4989	oxidoreductase activity
AXE83_RS07070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXE83_RS07070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXE83_RS07075	COG0577	efflux transmembrane transporter activity
AXE83_RS07080	COG1136	(ABC) transporter
AXE83_RS07085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXE83_RS07090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXE83_RS07095	COG1268	BioY protein
AXE83_RS07100	COG4443	Transcriptional Coactivator p15 (PC4)
AXE83_RS07110	COG1328	CTP reductase activity
AXE83_RS07110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AXE83_RS07165	COG0488	(ABC) transporter
AXE83_RS07175	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AXE83_RS07180	COG4470	Protein conserved in bacteria
AXE83_RS07185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AXE83_RS07200	COG2382	esterase
AXE83_RS07210	COG1104	cysteine desulfurase activity
AXE83_RS07225	COG0366	Alpha amylase catalytic
AXE83_RS07225	COG0366	Alpha amylase catalytic
AXE83_RS07230	COG1674	ftsk spoiiie
AXE83_RS07230	COG0697	spore germination
AXE83_RS07245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXE83_RS07245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXE83_RS07245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXE83_RS07250	COG1105	Belongs to the carbohydrate kinase PfkB family
AXE83_RS07265	COG1914	H( )-stimulated, divalent metal cation uptake system
AXE83_RS07275	COG0505	Belongs to the CarA family
AXE83_RS07290	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXE83_RS07305	COG0488	(ABC) transporter
AXE83_RS07315	COG1704	LemA family
AXE83_RS07335	COG0697	spore germination
AXE83_RS07355	COG1263	PTS System
AXE83_RS07355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXE83_RS07355	COG2190	(PTS) system
AXE83_RS07360	COG1242	4 iron, 4 sulfur cluster binding
AXE83_RS07365	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AXE83_RS07375	COG0025	NhaP-type Na H and K H
AXE83_RS07390	COG1301	dicarboxylic acid transport
AXE83_RS07400	COG0860	N-Acetylmuramoyl-L-alanine amidase
AXE83_RS07435	COG4555	ABC transporter
AXE83_RS07460	COG0191	fructose-bisphosphate aldolase activity
AXE83_RS07465	COG5002	protein histidine kinase activity
AXE83_RS07470	COG0745	RESPONSE REGULATOR receiver
AXE83_RS07475	COG0577	efflux transmembrane transporter activity
AXE83_RS07480	COG1136	(ABC) transporter
AXE83_RS07485	COG0577	efflux transmembrane transporter activity
AXE83_RS07495	COG1335	isochorismatase
AXE83_RS07500	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AXE83_RS07505	COG0513	Belongs to the DEAD box helicase family
AXE83_RS07510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXE83_RS07515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXE83_RS07520	COG3442	glutamine amidotransferase
AXE83_RS07525	COG0006	proline dipeptidase activity
AXE83_RS07540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AXE83_RS07560	COG1113	amino acid transport
AXE83_RS07570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AXE83_RS07595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AXE83_RS07600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AXE83_RS07605	COG0626	cystathionine gamma-synthase activity
AXE83_RS07610	COG4166	transmembrane transport
AXE83_RS07615	COG2244	polysaccharide biosynthetic process
AXE83_RS07620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXE83_RS07640	COG2827	Endonuclease containing a URI domain
AXE83_RS07645	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AXE83_RS07650	COG1098	S1 RNA binding domain
AXE83_RS07665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AXE83_RS07670	COG0629	single-stranded DNA binding
AXE83_RS07680	COG0617	tRNA 3'-terminal CCA addition
AXE83_RS07680	COG0517	IMP dehydrogenase activity
AXE83_RS07680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AXE83_RS07715	COG0740	serine-type endopeptidase activity
AXE83_RS07720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AXE83_RS07725	COG2131	deaminase
AXE83_RS07735	COG1307	EDD domain protein, DegV family
AXE83_RS07740	COG2081	HI0933 family
AXE83_RS07755	COG0789	Transcriptional regulator
AXE83_RS07765	COG0733	neurotransmitter:sodium symporter activity
AXE83_RS07770	COG1482	cell wall glycoprotein biosynthetic process
AXE83_RS07790	COG0028	Belongs to the TPP enzyme family
AXE83_RS07795	COG2217	Heavy metal translocating P-type atpase
AXE83_RS07805	COG3682	Transcriptional regulator
AXE83_RS07815	COG0765	amino acid transport
AXE83_RS07820	COG1126	abc transporter atp-binding protein
AXE83_RS07825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXE83_RS07840	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AXE83_RS07865	COG3250	beta-galactosidase activity
AXE83_RS07875	COG0366	Alpha amylase catalytic
AXE83_RS07880	COG1476	TRANSCRIPTIONal
AXE83_RS07890	COG0300	oxidoreductase activity
AXE83_RS07905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXE83_RS07925	COG1940	carbohydrate kinase activity
AXE83_RS07940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXE83_RS07945	COG3064	Membrane
AXE83_RS07950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXE83_RS07950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXE83_RS07955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AXE83_RS07960	COG3064	Membrane
AXE83_RS07980	COG0402	S-adenosylhomocysteine deaminase activity
AXE83_RS07995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXE83_RS07995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AXE83_RS08020	COG0242	peptide deformylase activity
AXE83_RS08030	COG0463	Glycosyl transferase, family 2
AXE83_RS08045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AXE83_RS08050	COG1940	carbohydrate kinase activity
AXE83_RS08055	COG2190	(PTS) system
AXE83_RS08055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AXE83_RS08055	COG1263	PTS System
AXE83_RS08060	COG1621	beta-fructofuranosidase activity
AXE83_RS08065	COG1609	Transcriptional regulator
AXE83_RS08075	COG3425	synthase
AXE83_RS08090	COG2815	serine threonine protein kinase
AXE83_RS08090	COG0515	serine threonine protein kinase
AXE83_RS08095	COG0631	protein serine/threonine phosphatase activity
AXE83_RS08100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AXE83_RS08100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AXE83_RS08110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXE83_RS08115	COG1758	RNA polymerase activity
AXE83_RS08120	COG0194	GDP metabolic process
AXE83_RS08145	COG2226	methyltransferase
AXE83_RS08150	COG0799	negative regulation of ribosome biogenesis
AXE83_RS08160	COG1713	HD superfamily hydrolase involved in NAD metabolism
AXE83_RS08165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AXE83_RS08170	COG1534	Rna-binding protein
AXE83_RS08175	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AXE83_RS08180	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AXE83_RS08190	COG0668	transmembrane transport
AXE83_RS08195	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AXE83_RS08210	COG1217	gtp-binding protein TYPA
AXE83_RS08260	COG3209	COG3209 Rhs family protein
AXE83_RS08275	COG1187	pseudouridine synthase activity
AXE83_RS08285	COG2801	Transposase and inactivated derivatives
AXE83_RS08290	COG2963	transposase activity
AXE83_RS08310	COG4720	Psort location CytoplasmicMembrane, score
AXE83_RS08315	COG0351	phosphomethylpyrimidine kinase
AXE83_RS08330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AXE83_RS08345	COG0135	phosphoribosylanthranilate isomerase activity
AXE83_RS08360	COG0512	Glutamine amidotransferase of anthranilate synthase
AXE83_RS08365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXE83_RS08375	COG0133	tryptophan synthase activity
AXE83_RS08380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AXE83_RS08385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AXE83_RS08390	COG1132	(ABC) transporter
AXE83_RS08395	COG1132	(ABC) transporter
AXE83_RS08400	COG0708	Exodeoxyribonuclease III
AXE83_RS08415	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AXE83_RS08420	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AXE83_RS08425	COG1609	Transcriptional regulator
AXE83_RS08430	COG1063	alcohol dehydrogenase
AXE83_RS08435	COG1230	cation diffusion facilitator family transporter
AXE83_RS08450	COG1174	glycine betaine transport
AXE83_RS08460	COG0604	alcohol dehydrogenase
AXE83_RS08470	COG1846	Transcriptional regulator
AXE83_RS08610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AXE83_RS08615	COG0588	phosphoglycerate mutase activity
AXE83_RS08635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AXE83_RS08640	COG3599	regulation of cell shape
AXE83_RS08645	COG3599	regulation of cell shape
AXE83_RS08655	COG0762	integral membrane protein
AXE83_RS08665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AXE83_RS08680	COG1091	dTDP-4-dehydrorhamnose reductase activity
AXE83_RS08685	COG1088	dTDP-glucose 4,6-dehydratase activity
AXE83_RS08695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AXE83_RS08700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AXE83_RS08705	COG3475	LICD family
AXE83_RS08730	COG0110	maltose O-acetyltransferase activity
AXE83_RS08750	COG0489	protein tyrosine kinase activity
AXE83_RS08755	COG3944	biosynthesis protein
AXE83_RS08760	COG4464	protein tyrosine phosphatase activity
AXE83_RS08770	COG4166	transmembrane transport
AXE83_RS08775	COG4166	transmembrane transport
AXE83_RS08780	COG0366	Alpha amylase catalytic
AXE83_RS08795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXE83_RS08805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXE83_RS08820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXE83_RS08825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXE83_RS08860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXE83_RS08865	COG3620	sequence-specific DNA binding
AXE83_RS08885	COG0281	malic enzyme
AXE83_RS08895	COG0583	DNA-binding transcription factor activity
AXE83_RS08950	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AXE83_RS08955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AXE83_RS08965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXE83_RS08980	COG0768	penicillin binding
AXE83_RS09005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXE83_RS09015	COG2731	YhcH YjgK YiaL family protein
AXE83_RS09020	COG0395	ABC-type sugar transport system, permease component
AXE83_RS09025	COG1175	transmembrane transport
AXE83_RS09055	COG4608	Belongs to the ABC transporter superfamily
AXE83_RS09060	COG0444	Belongs to the ABC transporter superfamily
AXE83_RS09065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXE83_RS09070	COG0601	transmembrane transport
AXE83_RS09075	COG4166	transmembrane transport
AXE83_RS09090	COG1253	flavin adenine dinucleotide binding
AXE83_RS09105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXE83_RS09115	COG3480	Lon protease (S16) C-terminal proteolytic domain
AXE83_RS09125	COG0742	ribosomal rna small subunit methyltransferase
AXE83_RS09140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXE83_RS09145	COG1254	Belongs to the acylphosphatase family
AXE83_RS09155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AXE83_RS09165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AXE83_RS09170	COG3481	metal-dependent phosphohydrolase, HD sub domain
AXE83_RS09180	COG1564	THIamine pyrophosphokinase
AXE83_RS09190	COG1162	GTPase activity
AXE83_RS09215	COG0084	hydrolase, TatD family'
AXE83_RS09220	COG0531	amino acid
AXE83_RS09230	COG0436	Aminotransferase
AXE83_RS09245	COG2801	Transposase and inactivated derivatives
AXE83_RS09250	COG2963	transposase activity
AXE83_RS09255	COG0166	Belongs to the GPI family
AXE83_RS09265	COG3732	PTS system glucitol sorbitol-specific
AXE83_RS09270	COG3730	PTS system glucitol sorbitol-specific
AXE83_RS09290	COG0166	Belongs to the GPI family
AXE83_RS09295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AXE83_RS09300	COG1132	(ABC) transporter
AXE83_RS09305	COG1132	(ABC) transporter
AXE83_RS09310	COG0588	phosphoglycerate mutase activity
AXE83_RS09340	COG1459	type II secretion system
AXE83_RS09345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AXE83_RS09355	COG1063	alcohol dehydrogenase
AXE83_RS09460	COG5002	protein histidine kinase activity
AXE83_RS09480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXE83_RS09500	COG3237	CsbD-like
AXE83_RS09520	COG0110	maltose O-acetyltransferase activity
AXE83_RS09540	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AXE83_RS09545	COG0803	Belongs to the bacterial solute-binding protein 9 family
AXE83_RS09545	COG3443	Belongs to the bacterial solute-binding protein 9 family
AXE83_RS09550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXE83_RS09555	COG1121	(ABC) transporter
AXE83_RS09560	COG1846	Transcriptional regulator
AXE83_RS09565	COG0737	Belongs to the 5'-nucleotidase family
AXE83_RS09570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AXE83_RS09580	COG1696	Membrane protein involved in D-alanine export
AXE83_RS09600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXE83_RS09625	COG3201	nicotinamide mononucleotide transporter
AXE83_RS09635	COG0542	response to heat
AXE83_RS09640	COG4463	regulation of RNA biosynthetic process
AXE83_RS09720	COG3177	Filamentation induced by cAMP protein fic
AXE83_RS09730	COG1116	anion transmembrane transporter activity
AXE83_RS09740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXE83_RS09750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXE83_RS09755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AXE83_RS09770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXE83_RS09780	COG1454	alcohol dehydrogenase
AXE83_RS09870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXE83_RS09875	COG0564	pseudouridine synthase activity
AXE83_RS09885	COG1012	belongs to the aldehyde dehydrogenase family
AXE83_RS09885	COG1454	alcohol dehydrogenase
AXE83_RS09895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AXE83_RS09900	COG1862	Preprotein translocase
AXE83_RS09905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXE83_RS09925	COG3623	hexulose-6-phosphate isomerase
AXE83_RS09935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXE83_RS09945	COG3037	sugar-specific permease SgaT UlaA
AXE83_RS09960	COG0706	membrane insertase activity
AXE83_RS09970	COG2848	UPF0210 protein
AXE83_RS09975	COG3830	Belongs to the UPF0237 family
AXE83_RS09985	COG0202	RNA polymerase activity
AXE83_RS09990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AXE83_RS09995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXE83_RS10000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AXE83_RS10005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AXE83_RS10015	COG0201	protein transport
AXE83_RS10030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AXE83_RS10050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AXE83_RS10070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AXE83_RS10080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AXE83_RS10095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AXE83_RS10110	COG0088	Forms part of the polypeptide exit tunnel
AXE83_RS10155	COG1328	CTP reductase activity
AXE83_RS10165	COG0445	tRNA wobble uridine modification
AXE83_RS10170	COG0494	nUDIX hydrolase
AXE83_RS10175	COG0494	nUDIX hydrolase
AXE83_RS10200	COG3584	3D domain protein
AXE83_RS10200	COG1388	LysM domain
AXE83_RS10205	COG1760	l-serine dehydratase
AXE83_RS10210	COG1760	l-serine dehydratase
AXE83_RS10215	COG0546	phosphoglycolate phosphatase activity
AXE83_RS10235	COG1216	Glycosyl transferase, family 2
AXE83_RS10240	COG2807	transmembrane transport
AXE83_RS10260	COG1695	Transcriptional regulator
AXE83_RS10295	COG1653	transport
AXE83_RS10300	COG0395	ABC-type sugar transport system, permease component
AXE83_RS10305	COG4209	transmembrane transport
AXE83_RS10320	COG0383	alpha-mannosidase activity