locus-tag	class	description
HAS68_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAS68_RS00010	COG0592	DNA-directed DNA polymerase activity
HAS68_RS00030	COG0012	GTP binding
HAS68_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
HAS68_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAS68_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HAS68_RS00065	COG0037	tRNA processing
HAS68_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAS68_RS00185	COG1792	Involved in formation and maintenance of cell shape
HAS68_RS00200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAS68_RS00205	COG0436	Aminotransferase
HAS68_RS00210	COG1381	Involved in DNA repair and RecF pathway recombination
HAS68_RS00215	COG0416	fatty acid biosynthetic process
HAS68_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAS68_RS00230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAS68_RS00245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAS68_RS00250	COG0138	bifunctional purine biosynthesis protein purh
HAS68_RS00275	COG0151	Belongs to the GarS family
HAS68_RS00295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAS68_RS00330	COG1131	(ABC) transporter
HAS68_RS00340	COG1132	(ABC) transporter
HAS68_RS00345	COG2255	four-way junction helicase activity
HAS68_RS00355	COG0546	phosphoglycolate phosphatase activity
HAS68_RS00365	COG0285	dihydrofolate synthase activity
HAS68_RS00380	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAS68_RS00385	COG0632	four-way junction helicase activity
HAS68_RS00390	COG0519	Catalyzes the synthesis of GMP from XMP
HAS68_RS00405	COG1393	Belongs to the ArsC family
HAS68_RS00410	COG4472	Bacterial protein of unknown function (DUF965)
HAS68_RS00415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAS68_RS00420	COG3906	Belongs to the UPF0473 family
HAS68_RS00435	COG0051	transcription antitermination factor activity, RNA binding
HAS68_RS00440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAS68_RS00445	COG0088	Forms part of the polypeptide exit tunnel
HAS68_RS00450	COG0089	rRNA binding
HAS68_RS00455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAS68_RS00460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAS68_RS00465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAS68_RS00470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAS68_RS00475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAS68_RS00480	COG0255	Belongs to the universal ribosomal protein uL29 family
HAS68_RS00485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAS68_RS00490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAS68_RS00495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAS68_RS00500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAS68_RS00505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAS68_RS00515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAS68_RS00525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAS68_RS00530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAS68_RS00535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAS68_RS00540	COG1841	ribosomal large subunit assembly
HAS68_RS00550	COG0201	protein transport
HAS68_RS00555	COG0563	adenylate kinase activity
HAS68_RS00560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAS68_RS00565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HAS68_RS00570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAS68_RS00580	COG0202	RNA polymerase activity
HAS68_RS00680	COG0582	viral genome integration into host DNA
HAS68_RS00690	COG2946	Replication initiation factor
HAS68_RS00700	COG1674	ftsk spoiiie
HAS68_RS00730	COG1121	(ABC) transporter
HAS68_RS00735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HAS68_RS00740	COG3443	Belongs to the bacterial solute-binding protein 9 family
HAS68_RS00740	COG0803	Belongs to the bacterial solute-binding protein 9 family
HAS68_RS00765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HAS68_RS00770	COG0085	RNA polymerase activity
HAS68_RS00775	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAS68_RS00785	COG1619	proteins homologs of microcin C7 resistance protein MccF
HAS68_RS00790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HAS68_RS00795	COG1459	type II secretion system
HAS68_RS00800	COG4537	Required for transformation and DNA binding
HAS68_RS00830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAS68_RS00840	COG0285	dihydrofolate synthase activity
HAS68_RS00845	COG1363	Peptidase, m42
HAS68_RS00855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HAS68_RS00865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAS68_RS00890	COG0459	protein refolding
HAS68_RS00900	COG0049	tRNA binding
HAS68_RS00905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAS68_RS00910	COG3590	peptidase
HAS68_RS00920	COG0126	phosphoglycerate kinase activity
HAS68_RS00930	COG0789	Transcriptional regulator
HAS68_RS00935	COG0174	glutamine synthetase
HAS68_RS00950	COG1214	PFAM Peptidase M22, glycoprotease
HAS68_RS00960	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAS68_RS00965	COG2207	Transcriptional regulator
HAS68_RS00975	COG1175	transmembrane transport
HAS68_RS00980	COG0395	ABC-type sugar transport system, permease component
HAS68_RS01000	COG2855	membrane
HAS68_RS01010	COG1131	(ABC) transporter
HAS68_RS01020	COG2081	HI0933 family
HAS68_RS01025	COG2723	6-phospho-beta-galactosidase activity
HAS68_RS01035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAS68_RS01050	COG3959	Transketolase, thiamine diphosphate binding domain
HAS68_RS01055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAS68_RS01060	COG0584	glycerophosphoryl diester phosphodiesterase
HAS68_RS01070	COG2222	sugar isomerase
HAS68_RS01095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HAS68_RS01110	COG3942	CHAP domain
HAS68_RS01115	COG1882	Formate acetyltransferase
HAS68_RS01130	COG2910	NAD(P)H-binding
HAS68_RS01155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HAS68_RS01180	COG0363	glucosamine-6-phosphate deaminase activity
HAS68_RS01185	COG2217	Heavy metal translocating P-type atpase
HAS68_RS01195	COG2217	Heavy metal translocating P-type atpase
HAS68_RS01200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HAS68_RS01205	COG0681	Belongs to the peptidase S26 family
HAS68_RS01225	COG0366	Alpha amylase catalytic
HAS68_RS01230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HAS68_RS01230	COG1263	PTS System
HAS68_RS01235	COG2188	Transcriptional regulator
HAS68_RS01250	COG1193	negative regulation of DNA recombination
HAS68_RS01315	COG3118	belongs to the thioredoxin family
HAS68_RS01325	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAS68_RS01325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAS68_RS01385	COG1115	amino acid carrier protein
HAS68_RS01420	COG3842	ATPase activity
HAS68_RS01430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HAS68_RS01445	COG0668	transmembrane transport
HAS68_RS01460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HAS68_RS01465	COG0167	dihydroorotate dehydrogenase activity
HAS68_RS01470	COG2843	Capsule synthesis protein
HAS68_RS01475	COG0561	phosphatase activity
HAS68_RS01490	COG1131	(ABC) transporter
HAS68_RS01495	COG1309	transcriptional regulator
HAS68_RS01515	COG1511	domain protein
HAS68_RS01540	COG1346	cytolysis
HAS68_RS01545	COG2116	formate transmembrane transporter activity
HAS68_RS01550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HAS68_RS01555	COG0433	COG0433 Predicted ATPase
HAS68_RS01560	COG0494	nUDIX hydrolase
HAS68_RS01585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HAS68_RS01590	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HAS68_RS01595	COG0124	histidyl-tRNA synthetase
HAS68_RS01600	COG1064	alcohol dehydrogenase
HAS68_RS01605	COG1454	alcohol dehydrogenase
HAS68_RS01605	COG1012	belongs to the aldehyde dehydrogenase family
HAS68_RS01625	COG1132	(ABC) transporter
HAS68_RS01635	COG0534	Mate efflux family protein
HAS68_RS01640	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HAS68_RS01655	COG1304	FMN binding
HAS68_RS01660	COG1132	(ABC) transporter
HAS68_RS01665	COG1132	(ABC) transporter
HAS68_RS01670	COG3830	Belongs to the UPF0237 family
HAS68_RS01675	COG2848	UPF0210 protein
HAS68_RS01680	COG0588	phosphoglycerate mutase activity
HAS68_RS01685	COG1420	regulation of RNA biosynthetic process
HAS68_RS01690	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAS68_RS01695	COG0443	Heat shock 70 kDa protein
HAS68_RS01700	COG0484	heat shock protein binding
HAS68_RS01705	COG0095	Lipoate-protein ligase
HAS68_RS01715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAS68_RS01720	COG0765	amino acid transport
HAS68_RS01735	COG3655	Transcriptional regulator
HAS68_RS01745	COG2217	Heavy metal translocating P-type atpase
HAS68_RS01780	COG4475	Protein of unknown function (DUF436)
HAS68_RS01805	COG4221	oxidoreductase activity
HAS68_RS01810	COG1902	pentaerythritol trinitrate reductase activity
HAS68_RS01810	COG0446	pyridine nucleotide-disulphide oxidoreductase
HAS68_RS01830	COG0544	peptidyl-prolyl cis-trans isomerase activity
HAS68_RS01855	COG2801	Transposase and inactivated derivatives
HAS68_RS01870	COG3343	RNA polymerase activity
HAS68_RS01875	COG0504	CTP synthase activity
HAS68_RS01885	COG0191	fructose-bisphosphate aldolase activity
HAS68_RS01890	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HAS68_RS01925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAS68_RS01955	COG0436	Aminotransferase
HAS68_RS01960	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HAS68_RS01965	COG1335	isochorismatase
HAS68_RS01975	COG0335	large ribosomal subunit rRNA binding
HAS68_RS01985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAS68_RS01990	COG0154	amidase activity
HAS68_RS01995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAS68_RS02000	COG1609	Transcriptional regulator
HAS68_RS02010	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HAS68_RS02025	COG3142	Participates in the control of copper homeostasis
HAS68_RS02040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HAS68_RS02045	COG1534	Rna-binding protein
HAS68_RS02050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAS68_RS02055	COG1713	HD superfamily hydrolase involved in NAD metabolism
HAS68_RS02070	COG0799	negative regulation of ribosome biogenesis
HAS68_RS02075	COG2226	methyltransferase
HAS68_RS02090	COG0789	Transcriptional regulator
HAS68_RS02100	COG0242	peptide deformylase activity
HAS68_RS02110	COG1640	4-alpha-glucanotransferase
HAS68_RS02115	COG0058	SHG alpha-glucan phosphorylase activity
HAS68_RS02130	COG1263	PTS System
HAS68_RS02130	COG2190	(PTS) system
HAS68_RS02130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HAS68_RS02145	COG0217	transcriptional regulatory protein
HAS68_RS02155	COG4720	Psort location CytoplasmicMembrane, score
HAS68_RS02165	COG1054	Belongs to the UPF0176 family
HAS68_RS02175	COG1122	ATPase activity
HAS68_RS02195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HAS68_RS02200	COG3331	DNA recombination
HAS68_RS02205	COG4474	Belongs to the UPF0398 family
HAS68_RS02210	COG3599	regulation of cell shape
HAS68_RS02215	COG0116	Belongs to the methyltransferase superfamily
HAS68_RS02230	COG1418	mRNA catabolic process
HAS68_RS02240	COG1758	RNA polymerase activity
HAS68_RS02245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAS68_RS02250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAS68_RS02255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAS68_RS02255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAS68_RS02260	COG0631	protein serine/threonine phosphatase activity
HAS68_RS02265	COG2815	serine threonine protein kinase
HAS68_RS02265	COG0515	serine threonine protein kinase
HAS68_RS02290	COG1098	S1 RNA binding domain
HAS68_RS02300	COG4974	Belongs to the 'phage' integrase family
HAS68_RS02460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAS68_RS02465	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAS68_RS02470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAS68_RS02485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HAS68_RS02490	COG3022	response to hydroperoxide
HAS68_RS02500	COG3944	biosynthesis protein
HAS68_RS02510	COG4464	protein tyrosine phosphatase activity
HAS68_RS02525	COG0438	transferase activity, transferring glycosyl groups
HAS68_RS02540	COG1216	Glycosyl transferase, family 2
HAS68_RS02540	COG1442	glycosyl transferase family 8
HAS68_RS02545	COG1216	Glycosyl transferase, family 2
HAS68_RS02545	COG1442	glycosyl transferase family 8
HAS68_RS02580	COG2089	acid synthase
HAS68_RS02595	COG1083	cytidylyl-transferase
HAS68_RS02595	COG2755	lipolytic protein G-D-S-L family
HAS68_RS02675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAS68_RS02680	COG0077	Prephenate dehydratase
HAS68_RS02690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAS68_RS02695	COG0562	UDP-galactopyranose mutase
HAS68_RS02700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HAS68_RS02715	COG0436	Aminotransferase
HAS68_RS02735	COG0534	Mate efflux family protein
HAS68_RS02740	COG0251	oxidation-reduction process
HAS68_RS02745	COG1660	Displays ATPase and GTPase activities
HAS68_RS02750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HAS68_RS02755	COG1481	regulation of sporulation
HAS68_RS02770	COG0454	-acetyltransferase
HAS68_RS02775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAS68_RS02780	COG0549	Belongs to the carbamate kinase family
HAS68_RS02785	COG1288	antiporter activity
HAS68_RS02790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAS68_RS02795	COG3064	Membrane
HAS68_RS02795	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HAS68_RS02795	COG3583	domain protein
HAS68_RS02800	COG1438	arginine binding
HAS68_RS02805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HAS68_RS02810	COG0363	glucosamine-6-phosphate deaminase activity
HAS68_RS02840	COG1696	Membrane protein involved in D-alanine export
HAS68_RS02845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAS68_RS02850	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HAS68_RS02860	COG0435	Glutathione S-transferase
HAS68_RS02865	COG1187	pseudouridine synthase activity
HAS68_RS02870	COG0386	Belongs to the glutathione peroxidase family
HAS68_RS02875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAS68_RS02880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAS68_RS02885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HAS68_RS02890	COG1120	ATPase activity
HAS68_RS02895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAS68_RS02900	COG0204	Acyl-transferase
HAS68_RS02905	COG1596	polysaccharide export
HAS68_RS02905	COG1555	photosystem II stabilization
HAS68_RS02910	COG0658	competence protein
HAS68_RS02910	COG2333	competence protein COMEC
HAS68_RS02920	COG0517	IMP dehydrogenase activity
HAS68_RS02935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAS68_RS02940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAS68_RS02945	COG0470	DNA polymerase III
HAS68_RS02950	COG4467	Involved in initiation control of chromosome replication
HAS68_RS02960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAS68_RS02970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HAS68_RS02975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAS68_RS02980	COG1393	Belongs to the ArsC family
HAS68_RS02990	COG0708	Exodeoxyribonuclease III
HAS68_RS03000	COG0531	amino acid
HAS68_RS03035	COG1061	Type III restriction enzyme res subunit
HAS68_RS03040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HAS68_RS03060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAS68_RS03065	COG4684	Psort location CytoplasmicMembrane, score
HAS68_RS03070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAS68_RS03080	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HAS68_RS03120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAS68_RS03125	COG1349	DNA-binding transcription factor activity
HAS68_RS03135	COG1447	Phosphotransferase system cellobiose-specific component IIA
HAS68_RS03140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HAS68_RS03145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HAS68_RS03150	COG1882	Formate acetyltransferase
HAS68_RS03170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAS68_RS03175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAS68_RS03185	COG1739	Uncharacterized protein family UPF0029
HAS68_RS03190	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HAS68_RS03270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAS68_RS03280	COG3557	Belongs to the UPF0374 family
HAS68_RS03290	COG2188	Transcriptional regulator
HAS68_RS03295	COG2188	Transcriptional regulator
HAS68_RS03305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HAS68_RS03315	COG3716	PTS system mannose fructose sorbose family IID component
HAS68_RS03325	COG2017	converts alpha-aldose to the beta-anomer
HAS68_RS03340	COG0346	lactoylglutathione lyase activity
HAS68_RS03375	COG0494	nUDIX hydrolase
HAS68_RS03390	COG1217	gtp-binding protein TYPA
HAS68_RS03405	COG0681	Belongs to the peptidase S26 family
HAS68_RS03435	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAS68_RS03450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAS68_RS03455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAS68_RS03460	COG1799	cell septum assembly
HAS68_RS03475	COG3599	regulation of cell shape
HAS68_RS03500	COG0406	alpha-ribazole phosphatase activity
HAS68_RS03500	COG0494	nUDIX hydrolase
HAS68_RS03505	COG0542	response to heat
HAS68_RS03510	COG4703	Protein of unknown function (DUF1797)
HAS68_RS03515	COG0765	amino acid transport
HAS68_RS03525	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAS68_RS03560	COG0789	Transcriptional regulator
HAS68_RS03575	COG0826	peptidase U32
HAS68_RS03585	COG4443	Transcriptional Coactivator p15 (PC4)
HAS68_RS03590	COG1268	BioY protein
HAS68_RS03600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAS68_RS03615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAS68_RS03620	COG1136	(ABC) transporter
HAS68_RS03625	COG0577	efflux transmembrane transporter activity
HAS68_RS03650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HAS68_RS03660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAS68_RS03670	COG3859	Proton-coupled thiamine transporter YuaJ
HAS68_RS03690	COG0772	Belongs to the SEDS family
HAS68_RS03695	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HAS68_RS03710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAS68_RS03715	COG0149	triose-phosphate isomerase activity
HAS68_RS03725	COG1078	dGTPase activity
HAS68_RS03760	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAS68_RS03765	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAS68_RS03770	COG2884	Cell division ATP-binding protein ftsE
HAS68_RS03775	COG2177	Part of the ABC transporter FtsEX involved in
HAS68_RS03795	COG1132	(ABC) transporter
HAS68_RS03800	COG1132	(ABC) transporter
HAS68_RS03805	COG1011	Hydrolase
HAS68_RS03825	COG1737	Transcriptional regulator
HAS68_RS03835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HAS68_RS03840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAS68_RS03845	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HAS68_RS03850	COG0237	dephospho-CoA kinase activity
HAS68_RS03855	COG2814	Major facilitator Superfamily
HAS68_RS03860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HAS68_RS03870	COG0557	exoribonuclease II activity
HAS68_RS03875	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HAS68_RS03880	COG1063	alcohol dehydrogenase
HAS68_RS03895	COG2217	Heavy metal translocating P-type atpase
HAS68_RS03900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HAS68_RS03910	COG1136	(ABC) transporter
HAS68_RS03920	COG3547	Transposase (IS116 IS110 IS902 family)
HAS68_RS03930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAS68_RS03930	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAS68_RS03940	COG1832	CoA-binding protein
HAS68_RS03950	COG0343	queuine tRNA-ribosyltransferase activity
HAS68_RS03960	COG1609	Transcriptional regulator
HAS68_RS03975	COG0438	transferase activity, transferring glycosyl groups
HAS68_RS03990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAS68_RS03995	COG0765	amino acid transport
HAS68_RS04000	COG0765	amino acid transport
HAS68_RS04005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAS68_RS04015	COG0745	RESPONSE REGULATOR receiver
HAS68_RS04025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HAS68_RS04040	COG0488	(ABC) transporter
HAS68_RS04045	COG0768	penicillin binding
HAS68_RS04050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAS68_RS04055	COG1181	Belongs to the D-alanine--D-alanine ligase family
HAS68_RS04075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HAS68_RS04085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HAS68_RS04100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAS68_RS04120	COG1609	Transcriptional regulator
HAS68_RS04125	COG4209	transmembrane transport
HAS68_RS04130	COG0395	ABC-type sugar transport system, permease component
HAS68_RS04135	COG1653	transport
HAS68_RS04140	COG1621	beta-fructofuranosidase activity
HAS68_RS04145	COG0697	spore germination
HAS68_RS04145	COG1674	ftsk spoiiie
HAS68_RS04150	COG0346	lactoylglutathione lyase activity
HAS68_RS04175	COG0625	glutathione transferase activity
HAS68_RS04180	COG2244	polysaccharide biosynthetic process
HAS68_RS04185	COG0528	UMP kinase activity
HAS68_RS04190	COG0233	cytoplasmic translational termination
HAS68_RS04195	COG2996	Protein conserved in bacteria
HAS68_RS04210	COG4479	Belongs to the UPF0346 family
HAS68_RS04220	COG0772	Belongs to the SEDS family
HAS68_RS04225	COG0693	protein deglycase activity
HAS68_RS04230	COG0187	DNA topoisomerase II activity
HAS68_RS04235	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HAS68_RS04240	COG0560	Phosphoserine phosphatase
HAS68_RS04360	COG1011	Hydrolase
HAS68_RS04370	COG2706	6-phosphogluconolactonase activity
HAS68_RS04375	COG0628	permease
HAS68_RS04385	COG3527	Alpha-acetolactate decarboxylase
HAS68_RS04390	COG1293	RNA-binding protein homologous to eukaryotic snRNP
HAS68_RS04395	COG3711	transcriptional antiterminator
HAS68_RS04400	COG2190	(PTS) system
HAS68_RS04400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HAS68_RS04400	COG1263	PTS System
HAS68_RS04420	COG3842	ATPase activity
HAS68_RS04455	COG0488	(ABC) transporter
HAS68_RS04465	COG2226	methyltransferase
HAS68_RS04470	COG3442	glutamine amidotransferase
HAS68_RS04475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HAS68_RS04490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAS68_RS04495	COG0488	(ABC) transporter
HAS68_RS04500	COG2226	methyltransferase
HAS68_RS04520	COG1573	uracil-dna glycosylase
HAS68_RS04530	COG1704	LemA family
HAS68_RS04535	COG2268	Band 7 protein
HAS68_RS04550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HAS68_RS04565	COG1518	maintenance of DNA repeat elements
HAS68_RS04580	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HAS68_RS04585	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HAS68_RS04595	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HAS68_RS04600	COG0813	purine-nucleoside phosphorylase activity
HAS68_RS04605	COG0058	SHG alpha-glucan phosphorylase activity
HAS68_RS04615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HAS68_RS04625	COG1051	belongs to the nudix hydrolase family
HAS68_RS04630	COG0647	UMP catabolic process
HAS68_RS04640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HAS68_RS04645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HAS68_RS04650	COG1970	mechanosensitive ion channel activity
HAS68_RS04655	COG0358	DNA primase activity
HAS68_RS04660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAS68_RS04665	COG2151	metal-sulfur cluster biosynthetic enzyme
HAS68_RS04690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HAS68_RS04700	COG1131	(ABC) transporter
HAS68_RS04705	COG2188	Transcriptional regulator
HAS68_RS04715	COG0205	6-phosphofructokinase activity
HAS68_RS04720	COG0469	pyruvate kinase activity
HAS68_RS04735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HAS68_RS04740	COG0657	acetylesterase activity
HAS68_RS04740	COG2755	lipolytic protein G-D-S-L family
HAS68_RS04755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HAS68_RS04760	COG0765	amino acid transport
HAS68_RS04765	COG1126	abc transporter atp-binding protein
HAS68_RS04770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAS68_RS04785	COG3684	Belongs to the aldolase LacD family
HAS68_RS04805	COG4120	Belongs to the binding-protein-dependent transport system permease family
HAS68_RS04810	COG1116	anion transmembrane transporter activity
HAS68_RS04810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HAS68_RS04815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAS68_RS04820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAS68_RS04825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAS68_RS04830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAS68_RS04840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAS68_RS04840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAS68_RS04865	COG4122	O-methyltransferase activity
HAS68_RS04870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HAS68_RS04880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAS68_RS04900	COG1476	TRANSCRIPTIONal
HAS68_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
HAS68_RS04960	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HAS68_RS04965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HAS68_RS04975	COG3716	PTS system mannose fructose sorbose family IID component
HAS68_RS04985	COG5492	domain, Protein
HAS68_RS05000	COG1609	Transcriptional regulator
HAS68_RS05005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAS68_RS05010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAS68_RS05015	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HAS68_RS05020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HAS68_RS05025	COG0372	Belongs to the citrate synthase family
HAS68_RS05030	COG0538	isocitrate dehydrogenase activity
HAS68_RS05035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAS68_RS05070	COG1196	nuclear chromosome segregation
HAS68_RS05075	COG0561	phosphatase activity
HAS68_RS05080	COG0561	phosphatase activity
HAS68_RS05085	COG0552	protein localization to endoplasmic reticulum
HAS68_RS05100	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAS68_RS05105	COG3689	TIGRFAM TIGR03943 family protein
HAS68_RS05110	COG0701	Predicted permease
HAS68_RS05120	COG1597	lipid kinase activity
HAS68_RS05130	COG0356	it plays a direct role in the translocation of protons across the membrane
HAS68_RS05135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAS68_RS05140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAS68_RS05145	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAS68_RS05150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAS68_RS05155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAS68_RS05160	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HAS68_RS05170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAS68_RS05185	COG2211	Major facilitator Superfamily
HAS68_RS05195	COG3250	beta-galactosidase activity
HAS68_RS05205	COG0800	Aldolase
HAS68_RS05215	COG1312	Catalyzes the dehydration of D-mannonate
HAS68_RS05220	COG1028	Short-chain dehydrogenase reductase Sdr
HAS68_RS05250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAS68_RS05250	COG0072	phenylalanine-tRNA ligase activity
HAS68_RS05275	COG1051	belongs to the nudix hydrolase family
HAS68_RS05280	COG0302	gtp cyclohydrolase
HAS68_RS05300	COG2610	gluconate transmembrane transporter activity
HAS68_RS05305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAS68_RS05320	COG1846	Transcriptional regulator
HAS68_RS05325	COG3759	membrane
HAS68_RS05345	COG1695	Transcriptional regulator
HAS68_RS05360	COG2195	Cleaves the N-terminal amino acid of tripeptides
HAS68_RS05365	COG0561	phosphatase activity
HAS68_RS05405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAS68_RS05410	COG0196	riboflavin kinase activity
HAS68_RS05415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HAS68_RS05420	COG1393	Belongs to the ArsC family
HAS68_RS05425	COG4476	Belongs to the UPF0223 family
HAS68_RS05430	COG0483	inositol monophosphate 1-phosphatase activity
HAS68_RS05435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAS68_RS05435	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HAS68_RS05445	COG0573	inorganic phosphate transmembrane transporter activity
HAS68_RS05450	COG0581	inorganic phosphate transmembrane transporter activity
HAS68_RS05455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HAS68_RS05460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HAS68_RS05465	COG0704	Plays a role in the regulation of phosphate uptake
HAS68_RS05480	COG0745	RESPONSE REGULATOR receiver
HAS68_RS05485	COG5002	protein histidine kinase activity
HAS68_RS05500	COG1072	(Pantothenic acid kinase))
HAS68_RS05505	COG2813	Specifically methylates the guanine in position
HAS68_RS05510	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HAS68_RS05525	COG1744	ABC transporter substrate-binding protein PnrA-like
HAS68_RS05530	COG3845	ABC transporter
HAS68_RS05535	COG4603	Belongs to the binding-protein-dependent transport system permease family
HAS68_RS05540	COG1079	Belongs to the binding-protein-dependent transport system permease family
HAS68_RS05545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HAS68_RS05555	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HAS68_RS05560	COG0039	L-malate dehydrogenase activity
HAS68_RS05565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAS68_RS05570	COG3764	Sortase (surface protein transpeptidase)
HAS68_RS05580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HAS68_RS05585	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HAS68_RS05600	COG1104	cysteine desulfurase activity
HAS68_RS05610	COG4116	CYTH
HAS68_RS05615	COG2357	RelA SpoT domain protein
HAS68_RS05620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAS68_RS05625	COG0564	pseudouridine synthase activity
HAS68_RS05630	COG0280	phosphate acetyltransferase
HAS68_RS05640	COG1132	(ABC) transporter
HAS68_RS05650	COG1194	a g-specific adenine glycosylase
HAS68_RS05655	COG1396	sequence-specific DNA binding
HAS68_RS05685	COG1349	DNA-binding transcription factor activity
HAS68_RS05690	COG0698	ribose 5-phosphate isomerase
HAS68_RS05695	COG0698	ribose 5-phosphate isomerase
HAS68_RS05700	COG1105	Belongs to the carbohydrate kinase PfkB family
HAS68_RS05705	COG3684	Belongs to the aldolase LacD family
HAS68_RS05710	COG3711	transcriptional antiterminator
HAS68_RS05720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HAS68_RS05720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HAS68_RS05745	COG2873	o-acetylhomoserine
HAS68_RS05750	COG0488	(ABC) transporter
HAS68_RS05760	COG1126	abc transporter atp-binding protein
HAS68_RS05810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAS68_RS05815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAS68_RS05825	COG0297	glycogen (starch) synthase activity
HAS68_RS05840	COG0583	DNA-binding transcription factor activity
HAS68_RS05850	COG0167	dihydroorotate dehydrogenase activity
HAS68_RS05855	COG0284	orotidine-5'-phosphate decarboxylase activity
HAS68_RS05860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HAS68_RS05870	COG0463	Glycosyl transferase, family 2
HAS68_RS05875	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAS68_RS05885	COG0737	Belongs to the 5'-nucleotidase family
HAS68_RS05890	COG0424	maF-like protein
HAS68_RS05900	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HAS68_RS05905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAS68_RS05915	COG1272	protein, Hemolysin III
HAS68_RS05925	COG0446	pyridine nucleotide-disulphide oxidoreductase
HAS68_RS05935	COG1937	Protein conserved in bacteria
HAS68_RS05940	COG0110	maltose O-acetyltransferase activity
HAS68_RS05945	COG0758	DNA mediated transformation
HAS68_RS05950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAS68_RS05955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAS68_RS05960	COG0222	ribosome binding
HAS68_RS05975	COG0270	DNA (cytosine-5-)-methyltransferase activity
HAS68_RS06095	COG1475	DNA binding
HAS68_RS06100	COG4443	Transcriptional Coactivator p15 (PC4)
HAS68_RS06155	COG1396	sequence-specific DNA binding
HAS68_RS06160	COG0542	response to heat
HAS68_RS06165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAS68_RS06180	COG0210	DNA helicase
HAS68_RS06200	COG3843	relaxase mobilization nuclease domain protein
HAS68_RS06215	COG1940	carbohydrate kinase activity
HAS68_RS06220	COG0698	ribose 5-phosphate isomerase
HAS68_RS06225	COG0698	ribose 5-phosphate isomerase
HAS68_RS06230	COG1105	Belongs to the carbohydrate kinase PfkB family
HAS68_RS06240	COG1447	Phosphotransferase system cellobiose-specific component IIA
HAS68_RS06260	COG1396	sequence-specific DNA binding
HAS68_RS06270	COG4974	Belongs to the 'phage' integrase family
HAS68_RS06320	COG1705	Flagellar rod assembly protein muramidase FlgJ
HAS68_RS06320	COG3942	CHAP domain
HAS68_RS06345	COG0270	DNA (cytosine-5-)-methyltransferase activity
HAS68_RS06360	COG0827	DNA restriction-modification system
HAS68_RS06380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAS68_RS06395	COG3843	relaxase mobilization nuclease domain protein
HAS68_RS06410	COG1070	Carbohydrate kinase
HAS68_RS06430	COG1175	transmembrane transport
HAS68_RS06435	COG0395	ABC-type sugar transport system, permease component
HAS68_RS06475	COG0647	UMP catabolic process
HAS68_RS06480	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HAS68_RS06485	COG3708	Transcriptional regulator
HAS68_RS06485	COG2207	Transcriptional regulator
HAS68_RS06495	COG2382	esterase
HAS68_RS06525	COG1136	(ABC) transporter
HAS68_RS06545	COG0745	RESPONSE REGULATOR receiver
HAS68_RS06560	COG4974	Belongs to the 'phage' integrase family
HAS68_RS06565	COG1660	Displays ATPase and GTPase activities
HAS68_RS06580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAS68_RS06585	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HAS68_RS06590	COG2188	Transcriptional regulator
HAS68_RS06600	COG4268	DNA restriction-modification system
HAS68_RS06605	COG1401	restriction endodeoxyribonuclease activity
HAS68_RS06630	COG4221	oxidoreductase activity
HAS68_RS06635	COG0741	lytic transglycosylase activity
HAS68_RS06645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAS68_RS06655	COG0009	L-threonylcarbamoyladenylate synthase
HAS68_RS06660	COG2890	protein-(glutamine-N5) methyltransferase activity
HAS68_RS06665	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAS68_RS06690	COG0481	GTPase activity
HAS68_RS06705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAS68_RS06715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HAS68_RS06720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAS68_RS06735	COG1940	carbohydrate kinase activity
HAS68_RS06745	COG0488	(ABC) transporter
HAS68_RS06750	COG0617	tRNA 3'-terminal CCA addition
HAS68_RS06755	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HAS68_RS06760	COG1307	EDD domain protein, DegV family
HAS68_RS06770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAS68_RS06770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HAS68_RS06770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HAS68_RS06775	COG1105	Belongs to the carbohydrate kinase PfkB family
HAS68_RS06780	COG1349	DNA-binding transcription factor activity
HAS68_RS06785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAS68_RS06790	COG0336	Belongs to the RNA methyltransferase TrmD family
HAS68_RS06795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAS68_RS06800	COG0534	Mate efflux family protein
HAS68_RS06810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAS68_RS06815	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HAS68_RS06825	COG0038	chloride channel
HAS68_RS06835	COG1177	transmembrane transport
HAS68_RS06840	COG1176	ABC-type spermidine putrescine transport system, permease component I
HAS68_RS06845	COG3842	ATPase activity
HAS68_RS06850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HAS68_RS06860	COG0083	homoserine kinase activity
HAS68_RS06870	COG0726	polysaccharide deacetylase
HAS68_RS06875	COG1132	(ABC) transporter
HAS68_RS06890	COG0228	four-way junction DNA binding
HAS68_RS06900	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HAS68_RS06905	COG2521	methyltransferase
HAS68_RS06905	COG2136	Putative SAM-dependent methyltransferase
HAS68_RS06915	COG0505	Belongs to the CarA family
HAS68_RS06920	COG0540	Belongs to the ATCase OTCase family
HAS68_RS06925	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HAS68_RS06935	COG2824	Alkylphosphonate utilization operon protein PhnA
HAS68_RS06940	COG0564	pseudouridine synthase activity
HAS68_RS06960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HAS68_RS06965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HAS68_RS06970	COG1114	Component of the transport system for branched-chain amino acids
HAS68_RS06975	COG0301	tRNA thio-modification
HAS68_RS06980	COG1104	cysteine desulfurase activity
HAS68_RS07005	COG0539	negative regulation of cytoplasmic translation
HAS68_RS07030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HAS68_RS07040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAS68_RS07055	COG2184	nucleotidyltransferase activity
HAS68_RS07060	COG0187	DNA topoisomerase II activity
HAS68_RS07070	COG1074	ATP-dependent DNA helicase activity
HAS68_RS07075	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HAS68_RS07105	COG1131	(ABC) transporter
HAS68_RS07135	COG1011	Hydrolase
HAS68_RS07145	COG0210	DNA helicase
HAS68_RS07160	COG1164	Oligoendopeptidase f
HAS68_RS07280	COG3679	Belongs to the UPF0342 family
HAS68_RS07285	COG0287	Prephenate dehydrogenase
HAS68_RS07290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAS68_RS07295	COG0710	3-dehydroquinate dehydratase activity
HAS68_RS07300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HAS68_RS07305	COG1368	sulfuric ester hydrolase activity
HAS68_RS07320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HAS68_RS07330	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HAS68_RS07375	COG1216	Glycosyl transferase, family 2
HAS68_RS07375	COG1442	glycosyl transferase family 8
HAS68_RS07380	COG1442	glycosyl transferase family 8
HAS68_RS07410	COG1216	Glycosyl transferase, family 2
HAS68_RS07410	COG1442	glycosyl transferase family 8
HAS68_RS07440	COG1091	dTDP-4-dehydrorhamnose reductase activity
HAS68_RS07445	COG1088	dTDP-glucose 4,6-dehydratase activity
HAS68_RS07460	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAS68_RS07470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HAS68_RS07475	COG2384	SAM-dependent methyltransferase
HAS68_RS07490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAS68_RS07500	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HAS68_RS07500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HAS68_RS07505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAS68_RS07515	COG0300	oxidoreductase activity
HAS68_RS07520	COG1234	tRNA 3'-trailer cleavage
HAS68_RS07530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAS68_RS07535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAS68_RS07545	COG2807	transmembrane transport
HAS68_RS07550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAS68_RS07555	COG1702	phosphate starvation-inducible protein PhoH
HAS68_RS07575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HAS68_RS07580	COG0716	FMN binding
HAS68_RS07590	COG1605	Chorismate mutase
HAS68_RS07590	COG0287	Prephenate dehydrogenase
HAS68_RS07595	COG0038	chloride channel
HAS68_RS07605	COG0737	Belongs to the 5'-nucleotidase family
HAS68_RS07610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAS68_RS07615	COG1466	dna polymerase III delta subunit
HAS68_RS07650	COG0683	leucine binding
HAS68_RS07665	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAS68_RS07670	COG0366	Alpha amylase catalytic
HAS68_RS07680	COG0395	ABC-type sugar transport system, permease component
HAS68_RS07685	COG1175	transmembrane transport
HAS68_RS07690	COG1653	transport
HAS68_RS07700	COG2207	Transcriptional regulator
HAS68_RS07705	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HAS68_RS07710	COG0626	cystathionine gamma-synthase activity
HAS68_RS07730	COG3547	Transposase (IS116 IS110 IS902 family)
HAS68_RS07735	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HAS68_RS07740	COG2827	Endonuclease containing a URI domain
HAS68_RS07760	COG0640	Transcriptional regulator
HAS68_RS07765	COG0513	Belongs to the DEAD box helicase family
HAS68_RS07770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAS68_RS07815	COG0494	nUDIX hydrolase
HAS68_RS07820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAS68_RS07830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAS68_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
HAS68_RS07860	COG0577	efflux transmembrane transporter activity
HAS68_RS07865	COG1136	(ABC) transporter
HAS68_RS07870	COG2205	protein histidine kinase activity
HAS68_RS07885	COG0436	Aminotransferase
HAS68_RS07895	COG1174	glycine betaine transport
HAS68_RS07900	COG1125	glycine betaine transport
HAS68_RS07900	COG0517	IMP dehydrogenase activity
HAS68_RS07920	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAS68_RS07925	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HAS68_RS07930	COG1482	cell wall glycoprotein biosynthetic process
HAS68_RS07945	COG3091	SprT-like family
HAS68_RS07950	COG2183	response to ionizing radiation
HAS68_RS07970	COG0656	L-ascorbic acid biosynthetic process
HAS68_RS07975	COG4708	membrane
HAS68_RS07980	COG2246	polysaccharide biosynthetic process
HAS68_RS07990	COG0024	Methionine aminopeptidase
HAS68_RS08000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAS68_RS08005	COG2249	NAD(P)H dehydrogenase (quinone) activity
HAS68_RS08010	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAS68_RS08020	COG2131	deaminase
HAS68_RS08040	COG1363	Peptidase, m42
HAS68_RS08055	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAS68_RS08060	COG1956	GAF domain-containing protein
HAS68_RS08080	COG0673	inositol 2-dehydrogenase activity
HAS68_RS08085	COG0513	Belongs to the DEAD box helicase family
HAS68_RS08090	COG0726	polysaccharide deacetylase
HAS68_RS08105	COG0183	Belongs to the thiolase family
HAS68_RS08110	COG3425	synthase
HAS68_RS08135	COG0776	regulation of translation
HAS68_RS08145	COG2755	lipolytic protein G-D-S-L family
HAS68_RS08150	COG1307	EDD domain protein, DegV family
HAS68_RS08155	COG0497	DNA recombination
HAS68_RS08160	COG1438	arginine binding
HAS68_RS08165	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HAS68_RS08175	COG1722	exodeoxyribonuclease VII activity
HAS68_RS08180	COG1570	exodeoxyribonuclease VII activity
HAS68_RS08185	COG2321	neutral zinc metallopeptidase
HAS68_RS08190	COG1755	Isoprenylcysteine carboxyl methyltransferase
HAS68_RS08195	COG5002	protein histidine kinase activity
HAS68_RS08200	COG0745	RESPONSE REGULATOR receiver
HAS68_RS08225	COG1227	inorganic diphosphatase activity
HAS68_RS08235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAS68_RS08240	COG1253	flavin adenine dinucleotide binding
HAS68_RS08245	COG1119	ATPase activity
HAS68_RS08250	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HAS68_RS08260	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAS68_RS08265	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HAS68_RS08280	COG4470	Protein conserved in bacteria
HAS68_RS08285	COG3480	Lon protease (S16) C-terminal proteolytic domain
HAS68_RS08290	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAS68_RS08295	COG0742	ribosomal rna small subunit methyltransferase
HAS68_RS08305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAS68_RS08310	COG4483	Protein conserved in bacteria
HAS68_RS08315	COG2197	response regulator
HAS68_RS08320	COG4585	Histidine kinase
HAS68_RS08320	COG2203	Gaf domain
HAS68_RS08325	COG0842	Transport permease protein
HAS68_RS08330	COG1131	(ABC) transporter
HAS68_RS08345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAS68_RS08355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HAS68_RS08355	COG2755	lipolytic protein G-D-S-L family
HAS68_RS08360	COG0671	phosphoesterase, PA-phosphatase related
HAS68_RS08365	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HAS68_RS08380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HAS68_RS08385	COG1187	pseudouridine synthase activity
HAS68_RS08390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAS68_RS08395	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAS68_RS08400	COG0582	viral genome integration into host DNA
HAS68_RS08420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HAS68_RS08425	COG3763	UPF0154 protein
HAS68_RS08435	COG3579	cysteine-type endopeptidase activity
HAS68_RS08450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAS68_RS08455	COG1254	Belongs to the acylphosphatase family
HAS68_RS08465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HAS68_RS08470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAS68_RS08480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HAS68_RS08490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HAS68_RS08505	COG1160	GTP binding
HAS68_RS08515	COG1484	DNA-dependent DNA replication
HAS68_RS08525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAS68_RS08530	COG0628	permease
HAS68_RS08535	COG0745	RESPONSE REGULATOR receiver
HAS68_RS08540	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAS68_RS08550	COG0492	ferredoxin-NADP+ reductase activity
HAS68_RS08560	COG0513	Belongs to the DEAD box helicase family
HAS68_RS08585	COG0768	penicillin binding
HAS68_RS08595	COG0275	rRNA processing
HAS68_RS08655	COG4939	FMN-binding domain protein
HAS68_RS08660	COG0142	geranyltranstransferase activity
HAS68_RS08665	COG1252	NADH dehydrogenase
HAS68_RS08680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HAS68_RS08685	COG0569	domain protein
HAS68_RS08690	COG0534	Mate efflux family protein
HAS68_RS08700	COG4224	UPF0291 protein
HAS68_RS08705	COG0751	glycine-tRNA ligase activity
HAS68_RS08730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAS68_RS08735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HAS68_RS08740	COG1464	Belongs to the NlpA lipoprotein family
HAS68_RS08745	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HAS68_RS08750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAS68_RS08755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HAS68_RS08770	COG0561	phosphatase activity
HAS68_RS08780	COG3715	PTS system
HAS68_RS08785	COG3716	PTS system mannose fructose sorbose family IID component
HAS68_RS08810	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HAS68_RS08845	COG0825	malonyl-CoA metabolic process
HAS68_RS08855	COG0439	Biotin carboxylase
HAS68_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
HAS68_RS08880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HAS68_RS08885	COG2070	2-Nitropropane dioxygenase
HAS68_RS08895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAS68_RS08905	COG1024	Enoyl-CoA hydratase
HAS68_RS08910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HAS68_RS08915	COG0527	aspartate kinase activity
HAS68_RS08925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAS68_RS08930	COG0736	holo-[acyl-carrier-protein] synthase activity
HAS68_RS08935	COG0653	protein targeting
HAS68_RS08945	COG1940	carbohydrate kinase activity
HAS68_RS08950	COG2190	(PTS) system
HAS68_RS08950	COG1263	PTS System
HAS68_RS08950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HAS68_RS08955	COG1621	beta-fructofuranosidase activity
HAS68_RS08960	COG1609	Transcriptional regulator
HAS68_RS08965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAS68_RS08980	COG0006	proline dipeptidase activity
HAS68_RS09000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAS68_RS09005	COG0629	single-stranded DNA binding
HAS68_RS09015	COG0095	Lipoate-protein ligase
HAS68_RS09020	COG2723	6-phospho-beta-galactosidase activity
HAS68_RS09035	COG2723	6-phospho-beta-galactosidase activity
HAS68_RS09040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HAS68_RS09050	COG1447	Phosphotransferase system cellobiose-specific component IIA
HAS68_RS09070	COG4095	Psort location CytoplasmicMembrane, score
HAS68_RS09075	COG2723	6-phospho-beta-galactosidase activity
HAS68_RS09080	COG0346	lactoylglutathione lyase activity
HAS68_RS09085	COG2723	6-phospho-beta-galactosidase activity
HAS68_RS09090	COG1917	Cupin 2, conserved barrel domain protein
HAS68_RS09090	COG2207	Transcriptional regulator
HAS68_RS09100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HAS68_RS09100	COG1263	PTS System
HAS68_RS09100	COG2190	(PTS) system
HAS68_RS09105	COG3711	transcriptional antiterminator
HAS68_RS09120	COG0508	dehydrogenase complex catalyzes the overall conversion of
HAS68_RS09125	COG0508	dehydrogenase complex catalyzes the overall conversion of
HAS68_RS09125	COG0022	dehydrogenase e1 component
HAS68_RS09130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HAS68_RS09135	COG2860	membrane
HAS68_RS09150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAS68_RS09155	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAS68_RS09165	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HAS68_RS09170	COG0195	Participates in both transcription termination and antitermination
HAS68_RS09180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HAS68_RS09190	COG4473	ABC transporter
HAS68_RS09195	COG1131	(ABC) transporter
HAS68_RS09200	COG0537	adenosine 5'-monophosphoramidase activity
HAS68_RS09210	COG1316	TRANSCRIPTIONal
HAS68_RS09220	COG0802	atpase or kinase
HAS68_RS09240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAS68_RS09245	COG0601	transmembrane transport
HAS68_RS09250	COG4608	Belongs to the ABC transporter superfamily
HAS68_RS09260	COG0747	negative chemotaxis
HAS68_RS09265	COG1686	Belongs to the peptidase S11 family
HAS68_RS09280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAS68_RS09285	COG0719	Fe-S assembly protein
HAS68_RS09300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAS68_RS09305	COG4862	establishment of competence for transformation
HAS68_RS09310	COG1968	undecaprenyl-diphosphatase activity
HAS68_RS09315	COG0765	amino acid transport
HAS68_RS09320	COG1126	abc transporter atp-binding protein
HAS68_RS09335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HAS68_RS09340	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAS68_RS09345	COG0440	acetolactate synthase activity
HAS68_RS09350	COG0028	Belongs to the TPP enzyme family
HAS68_RS09355	COG0463	Glycosyl transferase, family 2
HAS68_RS09370	COG0129	dihydroxy-acid dehydratase activity
HAS68_RS09380	COG2151	metal-sulfur cluster biosynthetic enzyme
HAS68_RS09430	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAS68_RS09445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAS68_RS09460	COG3842	ATPase activity
HAS68_RS09470	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HAS68_RS09490	COG1045	serine acetyltransferase
HAS68_RS09495	COG1185	polyribonucleotide nucleotidyltransferase activity
HAS68_RS09500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAS68_RS09505	COG1131	(ABC) transporter
HAS68_RS09545	COG2801	Transposase and inactivated derivatives
HAS68_RS09555	COG1187	pseudouridine synthase activity
HAS68_RS09570	COG0242	peptide deformylase activity
HAS68_RS09580	COG0066	3-isopropylmalate dehydratase activity
HAS68_RS09600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HAS68_RS09610	COG2188	Transcriptional regulator
HAS68_RS09615	COG1447	Phosphotransferase system cellobiose-specific component IIA
HAS68_RS09630	COG2309	aminopeptidase activity
HAS68_RS09650	COG2176	DNA-directed DNA polymerase activity
HAS68_RS09655	COG2376	Dihydroxyacetone kinase
HAS68_RS09665	COG2376	Dihydroxyacetone kinase
HAS68_RS09670	COG1461	Dihydroxyacetone kinase
HAS68_RS09675	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HAS68_RS09680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HAS68_RS09685	COG0442	prolyl-tRNA aminoacylation
HAS68_RS09695	COG4589	Belongs to the CDS family
HAS68_RS09700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAS68_RS09705	COG1862	Preprotein translocase
HAS68_RS09715	COG2918	glutathione biosynthetic process
HAS68_RS09715	COG1181	Belongs to the D-alanine--D-alanine ligase family
HAS68_RS09730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAS68_RS09735	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAS68_RS09740	COG0542	response to heat
HAS68_RS09745	COG4463	regulation of RNA biosynthetic process
HAS68_RS09755	COG1388	LysM domain
HAS68_RS09755	COG4932	domain protein
HAS68_RS09765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAS68_RS09800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HAS68_RS09805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HAS68_RS09810	COG0492	ferredoxin-NADP+ reductase activity
HAS68_RS09815	COG0564	pseudouridine synthase activity
HAS68_RS09965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAS68_RS09985	COG1564	THIamine pyrophosphokinase
HAS68_RS09995	COG1162	GTPase activity
HAS68_RS10005	COG1132	(ABC) transporter
HAS68_RS10030	COG4115	mRNA cleavage
HAS68_RS10055	COG0084	hydrolase, TatD family'
HAS68_RS10065	COG1847	R3H domain protein
HAS68_RS10075	COG0594	ribonuclease P activity
HAS68_RS10080	COG0165	Argininosuccinate lyase
HAS68_RS10085	COG0137	argininosuccinate synthase activity
HAS68_RS10095	COG1827	regulation of RNA biosynthetic process
HAS68_RS10150	COG0756	dUTP diphosphatase activity
HAS68_RS10155	COG1132	(ABC) transporter
HAS68_RS10160	COG1132	(ABC) transporter
HAS68_RS10170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HAS68_RS10175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HAS68_RS10180	COG0705	Rhomboid family
HAS68_RS10185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HAS68_RS10190	COG1473	amidohydrolase
HAS68_RS10195	COG2171	N-acyltransferase activity
HAS68_RS10205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HAS68_RS10225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HAS68_RS10250	COG3623	hexulose-6-phosphate isomerase
HAS68_RS10275	COG1523	belongs to the glycosyl hydrolase 13 family
HAS68_RS10280	COG1609	Transcriptional regulator
HAS68_RS10285	COG1126	abc transporter atp-binding protein
HAS68_RS10290	COG0765	amino acid transport
HAS68_RS10295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAS68_RS10300	COG3942	CHAP domain
HAS68_RS10305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HAS68_RS10315	COG1447	Phosphotransferase system cellobiose-specific component IIA
HAS68_RS10325	COG3711	transcriptional antiterminator
HAS68_RS10325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HAS68_RS10335	COG2723	6-phospho-beta-galactosidase activity
HAS68_RS10340	COG1486	melibiose metabolic process
HAS68_RS10350	COG3590	peptidase
HAS68_RS10355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HAS68_RS10360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HAS68_RS10360	COG1321	iron dependent repressor
HAS68_RS10365	COG1121	(ABC) transporter
HAS68_RS10375	COG0803	Belongs to the bacterial solute-binding protein 9 family
HAS68_RS10395	COG1490	D-aminoacyl-tRNA deacylase activity
HAS68_RS10405	COG0737	Belongs to the 5'-nucleotidase family
HAS68_RS10425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HAS68_RS10445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HAS68_RS10470	COG0737	Belongs to the 5'-nucleotidase family
HAS68_RS10485	COG1126	abc transporter atp-binding protein
HAS68_RS10495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HAS68_RS10500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HAS68_RS10515	COG1438	arginine binding
HAS68_RS10520	COG0018	arginyl-trna synthetase
HAS68_RS10540	COG1640	4-alpha-glucanotransferase
HAS68_RS10545	COG2182	Extracellular solute-binding protein
HAS68_RS10550	COG1175	transmembrane transport
HAS68_RS10555	COG3833	ABC-type maltose transport systems, permease component
HAS68_RS10560	COG5521	maltodextrose utilization protein MalA
HAS68_RS10565	COG1609	Transcriptional regulator
HAS68_RS10570	COG1523	belongs to the glycosyl hydrolase 13 family
HAS68_RS10575	COG1780	Probably involved in ribonucleotide reductase function
HAS68_RS10580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAS68_RS10585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HAS68_RS10590	COG2153	protein acetylation
HAS68_RS10595	COG4989	oxidoreductase activity
HAS68_RS10600	COG1216	Glycosyl transferase, family 2
HAS68_RS10620	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAS68_RS10630	COG0305	Participates in initiation and elongation during chromosome replication
HAS68_RS10635	COG0359	binds to the 23S rRNA
HAS68_RS10645	COG0445	tRNA wobble uridine modification
HAS68_RS10650	COG0494	nUDIX hydrolase
HAS68_RS10655	COG1733	regulation of RNA biosynthetic process
HAS68_RS10665	COG0482	sulfurtransferase activity
HAS68_RS10670	COG1760	l-serine dehydratase
HAS68_RS10675	COG1760	l-serine dehydratase
HAS68_RS10685	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAS68_RS10690	COG1122	ATPase activity
HAS68_RS10695	COG1122	ATPase activity
HAS68_RS10700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAS68_RS10705	COG1426	Protein conserved in bacteria
HAS68_RS10710	COG0612	Peptidase, M16
HAS68_RS10715	COG0612	Peptidase, M16
HAS68_RS10790	COG0582	viral genome integration into host DNA
HAS68_RS10800	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAS68_RS10810	COG0516	GMP reductase activity
HAS68_RS10810	COG0517	IMP dehydrogenase activity
HAS68_RS10820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAS68_RS10825	COG0488	(ABC) transporter
HAS68_RS10855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAS68_RS10860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAS68_RS10865	COG1475	DNA binding