locus-tag	class	description
KPA27_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPA27_RS00010	COG0592	DNA-directed DNA polymerase activity
KPA27_RS00030	COG0012	GTP binding
KPA27_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
KPA27_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPA27_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KPA27_RS00060	COG0037	tRNA processing
KPA27_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPA27_RS00180	COG1792	Involved in formation and maintenance of cell shape
KPA27_RS00195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPA27_RS00200	COG0436	Aminotransferase
KPA27_RS00205	COG1381	Involved in DNA repair and RecF pathway recombination
KPA27_RS00210	COG0416	fatty acid biosynthetic process
KPA27_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPA27_RS00225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPA27_RS00240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KPA27_RS00245	COG0138	bifunctional purine biosynthesis protein purh
KPA27_RS00255	COG0151	Belongs to the GarS family
KPA27_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KPA27_RS00275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KPA27_RS00310	COG2255	four-way junction helicase activity
KPA27_RS00320	COG0546	phosphoglycolate phosphatase activity
KPA27_RS00335	COG0285	dihydrofolate synthase activity
KPA27_RS00345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KPA27_RS00350	COG0632	four-way junction helicase activity
KPA27_RS00355	COG0519	Catalyzes the synthesis of GMP from XMP
KPA27_RS00370	COG1393	Belongs to the ArsC family
KPA27_RS00375	COG4472	Bacterial protein of unknown function (DUF965)
KPA27_RS00380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPA27_RS00385	COG3906	Belongs to the UPF0473 family
KPA27_RS00395	COG0051	transcription antitermination factor activity, RNA binding
KPA27_RS00400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPA27_RS00405	COG0088	Forms part of the polypeptide exit tunnel
KPA27_RS00410	COG0089	rRNA binding
KPA27_RS00415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPA27_RS00420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KPA27_RS00425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KPA27_RS00430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KPA27_RS00435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KPA27_RS00440	COG0255	Belongs to the universal ribosomal protein uL29 family
KPA27_RS00445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPA27_RS00450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KPA27_RS00455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPA27_RS00460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPA27_RS00465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPA27_RS00470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPA27_RS00475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KPA27_RS00480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPA27_RS00485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KPA27_RS00490	COG1841	ribosomal large subunit assembly
KPA27_RS00500	COG0201	protein transport
KPA27_RS00505	COG0563	adenylate kinase activity
KPA27_RS00510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KPA27_RS00515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KPA27_RS00520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPA27_RS00530	COG0202	RNA polymerase activity
KPA27_RS00640	COG1121	(ABC) transporter
KPA27_RS00645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KPA27_RS00650	COG0803	Belongs to the bacterial solute-binding protein 9 family
KPA27_RS00650	COG3443	Belongs to the bacterial solute-binding protein 9 family
KPA27_RS00690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPA27_RS00695	COG0085	RNA polymerase activity
KPA27_RS00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPA27_RS00710	COG1619	proteins homologs of microcin C7 resistance protein MccF
KPA27_RS00715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KPA27_RS00720	COG1459	type II secretion system
KPA27_RS00725	COG4537	Required for transformation and DNA binding
KPA27_RS00755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPA27_RS00765	COG0285	dihydrofolate synthase activity
KPA27_RS00770	COG1363	Peptidase, m42
KPA27_RS00780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPA27_RS00790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPA27_RS00820	COG0459	protein refolding
KPA27_RS00830	COG0049	tRNA binding
KPA27_RS00835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KPA27_RS00845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KPA27_RS00865	COG0126	phosphoglycerate kinase activity
KPA27_RS00875	COG0789	Transcriptional regulator
KPA27_RS00880	COG0174	glutamine synthetase
KPA27_RS00900	COG1214	PFAM Peptidase M22, glycoprotease
KPA27_RS00910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KPA27_RS00920	COG2207	Transcriptional regulator
KPA27_RS00930	COG1175	transmembrane transport
KPA27_RS00935	COG0395	ABC-type sugar transport system, permease component
KPA27_RS00955	COG2855	membrane
KPA27_RS00965	COG1846	Transcriptional regulator
KPA27_RS00965	COG0456	acetyltransferase
KPA27_RS00980	COG1131	(ABC) transporter
KPA27_RS00985	COG2081	HI0933 family
KPA27_RS00990	COG2723	6-phospho-beta-galactosidase activity
KPA27_RS01000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPA27_RS01015	COG3959	Transketolase, thiamine diphosphate binding domain
KPA27_RS01020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KPA27_RS01025	COG0584	glycerophosphoryl diester phosphodiesterase
KPA27_RS01030	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KPA27_RS01035	COG2222	sugar isomerase
KPA27_RS01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KPA27_RS01065	COG1882	Formate acetyltransferase
KPA27_RS01080	COG2910	NAD(P)H-binding
KPA27_RS01095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KPA27_RS01100	COG0681	Belongs to the peptidase S26 family
KPA27_RS01120	COG0366	Alpha amylase catalytic
KPA27_RS01125	COG1263	PTS System
KPA27_RS01125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPA27_RS01130	COG2188	Transcriptional regulator
KPA27_RS01145	COG1193	negative regulation of DNA recombination
KPA27_RS01160	COG0656	L-ascorbic acid biosynthetic process
KPA27_RS01165	COG3118	belongs to the thioredoxin family
KPA27_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
KPA27_RS01175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPA27_RS01175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPA27_RS01200	COG1115	amino acid carrier protein
KPA27_RS01205	COG0668	transmembrane transport
KPA27_RS01215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KPA27_RS01220	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS01230	COG0167	dihydroorotate dehydrogenase activity
KPA27_RS01235	COG2843	Capsule synthesis protein
KPA27_RS01260	COG0561	phosphatase activity
KPA27_RS01275	COG1131	(ABC) transporter
KPA27_RS01280	COG1309	transcriptional regulator
KPA27_RS01285	COG1511	domain protein
KPA27_RS01310	COG1346	cytolysis
KPA27_RS01315	COG2116	formate transmembrane transporter activity
KPA27_RS01320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KPA27_RS01325	COG0433	COG0433 Predicted ATPase
KPA27_RS01330	COG0494	nUDIX hydrolase
KPA27_RS01335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KPA27_RS01355	COG1349	DNA-binding transcription factor activity
KPA27_RS01360	COG0698	ribose 5-phosphate isomerase
KPA27_RS01365	COG0698	ribose 5-phosphate isomerase
KPA27_RS01370	COG1105	Belongs to the carbohydrate kinase PfkB family
KPA27_RS01380	COG3711	transcriptional antiterminator
KPA27_RS01390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPA27_RS01390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPA27_RS01405	COG1408	metallophosphoesterase
KPA27_RS01410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KPA27_RS01415	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KPA27_RS01420	COG0124	histidyl-tRNA synthetase
KPA27_RS01425	COG1064	alcohol dehydrogenase
KPA27_RS01430	COG1012	belongs to the aldehyde dehydrogenase family
KPA27_RS01430	COG1454	alcohol dehydrogenase
KPA27_RS01440	COG4988	ABC transporter
KPA27_RS01445	COG1132	(ABC) transporter
KPA27_RS01460	COG1129	ABC transporter
KPA27_RS01465	COG0534	Mate efflux family protein
KPA27_RS01470	COG1132	(ABC) transporter
KPA27_RS01480	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KPA27_RS01495	COG1304	FMN binding
KPA27_RS01500	COG1132	(ABC) transporter
KPA27_RS01505	COG1132	(ABC) transporter
KPA27_RS01510	COG3830	Belongs to the UPF0237 family
KPA27_RS01515	COG2848	UPF0210 protein
KPA27_RS01520	COG0588	phosphoglycerate mutase activity
KPA27_RS01535	COG1396	sequence-specific DNA binding
KPA27_RS01560	COG1420	regulation of RNA biosynthetic process
KPA27_RS01565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KPA27_RS01570	COG0443	Heat shock 70 kDa protein
KPA27_RS01575	COG0484	heat shock protein binding
KPA27_RS01580	COG0095	Lipoate-protein ligase
KPA27_RS01590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPA27_RS01595	COG0765	amino acid transport
KPA27_RS01600	COG3655	Transcriptional regulator
KPA27_RS01610	COG2217	Heavy metal translocating P-type atpase
KPA27_RS01635	COG4475	Protein of unknown function (DUF436)
KPA27_RS01645	COG1064	alcohol dehydrogenase
KPA27_RS01660	COG0544	peptidyl-prolyl cis-trans isomerase activity
KPA27_RS01665	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KPA27_RS01675	COG0251	oxidation-reduction process
KPA27_RS01680	COG0626	cystathionine gamma-synthase activity
KPA27_RS01685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KPA27_RS01690	COG2964	Protein conserved in bacteria
KPA27_RS01730	COG3343	RNA polymerase activity
KPA27_RS01735	COG0504	CTP synthase activity
KPA27_RS01745	COG0191	fructose-bisphosphate aldolase activity
KPA27_RS01750	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KPA27_RS01785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KPA27_RS01810	COG0589	response to stress
KPA27_RS01815	COG0436	Aminotransferase
KPA27_RS01820	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KPA27_RS01825	COG1335	isochorismatase
KPA27_RS01830	COG0335	large ribosomal subunit rRNA binding
KPA27_RS01840	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPA27_RS01845	COG0154	amidase activity
KPA27_RS01850	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPA27_RS01855	COG1609	Transcriptional regulator
KPA27_RS01860	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KPA27_RS01865	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KPA27_RS01875	COG3142	Participates in the control of copper homeostasis
KPA27_RS01890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KPA27_RS01895	COG1534	Rna-binding protein
KPA27_RS01900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPA27_RS01905	COG1713	HD superfamily hydrolase involved in NAD metabolism
KPA27_RS01915	COG1335	isochorismatase
KPA27_RS01920	COG0799	negative regulation of ribosome biogenesis
KPA27_RS01925	COG2226	methyltransferase
KPA27_RS01935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KPA27_RS01940	COG0789	Transcriptional regulator
KPA27_RS01950	COG0242	peptide deformylase activity
KPA27_RS01960	COG1640	4-alpha-glucanotransferase
KPA27_RS01965	COG0058	SHG alpha-glucan phosphorylase activity
KPA27_RS01980	COG1263	PTS System
KPA27_RS01980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPA27_RS01980	COG2190	(PTS) system
KPA27_RS01985	COG0217	transcriptional regulatory protein
KPA27_RS01995	COG4720	Psort location CytoplasmicMembrane, score
KPA27_RS02005	COG1054	Belongs to the UPF0176 family
KPA27_RS02015	COG1122	ATPase activity
KPA27_RS02030	COG0357	Ribosomal RNA small subunit methyltransferase G
KPA27_RS02035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPA27_RS02040	COG3331	DNA recombination
KPA27_RS02045	COG4474	Belongs to the UPF0398 family
KPA27_RS02050	COG3599	regulation of cell shape
KPA27_RS02060	COG0116	Belongs to the methyltransferase superfamily
KPA27_RS02070	COG1854	S-ribosylhomocysteine lyase activity
KPA27_RS02075	COG1418	mRNA catabolic process
KPA27_RS02085	COG1758	RNA polymerase activity
KPA27_RS02090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPA27_RS02095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPA27_RS02100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KPA27_RS02100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPA27_RS02105	COG0631	protein serine/threonine phosphatase activity
KPA27_RS02110	COG0515	serine threonine protein kinase
KPA27_RS02110	COG2815	serine threonine protein kinase
KPA27_RS02140	COG1098	S1 RNA binding domain
KPA27_RS02150	COG1739	Uncharacterized protein family UPF0029
KPA27_RS02155	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KPA27_RS02245	COG2217	Heavy metal translocating P-type atpase
KPA27_RS02285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPA27_RS02295	COG3557	Belongs to the UPF0374 family
KPA27_RS02305	COG2188	Transcriptional regulator
KPA27_RS02365	COG2188	Transcriptional regulator
KPA27_RS02375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPA27_RS02385	COG3716	PTS system mannose fructose sorbose family IID component
KPA27_RS02395	COG2017	converts alpha-aldose to the beta-anomer
KPA27_RS02410	COG0346	lactoylglutathione lyase activity
KPA27_RS02470	COG1217	gtp-binding protein TYPA
KPA27_RS02485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KPA27_RS02505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KPA27_RS02510	COG1799	cell septum assembly
KPA27_RS02525	COG3599	regulation of cell shape
KPA27_RS02545	COG0406	alpha-ribazole phosphatase activity
KPA27_RS02545	COG0494	nUDIX hydrolase
KPA27_RS02550	COG0542	response to heat
KPA27_RS02555	COG4703	Protein of unknown function (DUF1797)
KPA27_RS02560	COG0765	amino acid transport
KPA27_RS02570	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPA27_RS02595	COG2321	neutral zinc metallopeptidase
KPA27_RS02600	COG1570	exodeoxyribonuclease VII activity
KPA27_RS02605	COG1722	exodeoxyribonuclease VII activity
KPA27_RS02615	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KPA27_RS02620	COG1438	arginine binding
KPA27_RS02625	COG0497	DNA recombination
KPA27_RS02630	COG1307	EDD domain protein, DegV family
KPA27_RS02635	COG2755	lipolytic protein G-D-S-L family
KPA27_RS02645	COG0776	regulation of translation
KPA27_RS02650	COG0582	viral genome integration into host DNA
KPA27_RS02800	COG1783	phage Terminase large subunit
KPA27_RS02945	COG3425	synthase
KPA27_RS02950	COG0183	Belongs to the thiolase family
KPA27_RS02965	COG0726	polysaccharide deacetylase
KPA27_RS02970	COG0513	Belongs to the DEAD box helicase family
KPA27_RS02975	COG0673	inositol 2-dehydrogenase activity
KPA27_RS02985	COG1695	Transcriptional regulator
KPA27_RS02995	COG1956	GAF domain-containing protein
KPA27_RS03000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPA27_RS03015	COG1363	Peptidase, m42
KPA27_RS03035	COG2131	deaminase
KPA27_RS03040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPA27_RS03045	COG2249	NAD(P)H dehydrogenase (quinone) activity
KPA27_RS03050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPA27_RS03060	COG0024	Methionine aminopeptidase
KPA27_RS03075	COG2246	polysaccharide biosynthetic process
KPA27_RS03080	COG4708	membrane
KPA27_RS03085	COG0656	L-ascorbic acid biosynthetic process
KPA27_RS03090	COG2183	response to ionizing radiation
KPA27_RS03095	COG3091	SprT-like family
KPA27_RS03110	COG1482	cell wall glycoprotein biosynthetic process
KPA27_RS03115	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KPA27_RS03120	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPA27_RS03135	COG1733	regulation of RNA biosynthetic process
KPA27_RS03160	COG1125	glycine betaine transport
KPA27_RS03160	COG0517	IMP dehydrogenase activity
KPA27_RS03165	COG1174	glycine betaine transport
KPA27_RS03175	COG1309	transcriptional regulator
KPA27_RS03185	COG1131	(ABC) transporter
KPA27_RS03200	COG0436	Aminotransferase
KPA27_RS03215	COG2205	protein histidine kinase activity
KPA27_RS03220	COG1136	(ABC) transporter
KPA27_RS03225	COG0577	efflux transmembrane transporter activity
KPA27_RS03250	COG1028	Short-chain dehydrogenase reductase Sdr
KPA27_RS03255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPA27_RS03270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPA27_RS03275	COG0494	nUDIX hydrolase
KPA27_RS03315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPA27_RS03335	COG1609	Transcriptional regulator
KPA27_RS03340	COG4209	transmembrane transport
KPA27_RS03345	COG0395	ABC-type sugar transport system, permease component
KPA27_RS03350	COG1653	transport
KPA27_RS03355	COG1621	beta-fructofuranosidase activity
KPA27_RS03360	COG0697	spore germination
KPA27_RS03360	COG1674	ftsk spoiiie
KPA27_RS03365	COG0346	lactoylglutathione lyase activity
KPA27_RS03395	COG0625	glutathione transferase activity
KPA27_RS03400	COG2244	polysaccharide biosynthetic process
KPA27_RS03405	COG0528	UMP kinase activity
KPA27_RS03410	COG0233	cytoplasmic translational termination
KPA27_RS03415	COG2996	Protein conserved in bacteria
KPA27_RS03430	COG4479	Belongs to the UPF0346 family
KPA27_RS03435	COG1702	phosphate starvation-inducible protein PhoH
KPA27_RS03455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPA27_RS03460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KPA27_RS03465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPA27_RS03480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPA27_RS03485	COG3022	response to hydroperoxide
KPA27_RS03490	COG1316	TRANSCRIPTIONal
KPA27_RS03495	COG3944	biosynthesis protein
KPA27_RS03505	COG4464	protein tyrosine phosphatase activity
KPA27_RS03515	COG3177	Filamentation induced by cAMP protein fic
KPA27_RS03520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KPA27_RS03525	COG1216	Glycosyl transferase, family 2
KPA27_RS03560	COG1216	Glycosyl transferase, family 2
KPA27_RS03575	COG0562	UDP-galactopyranose mutase
KPA27_RS03580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KPA27_RS03595	COG0436	Aminotransferase
KPA27_RS03605	COG0534	Mate efflux family protein
KPA27_RS03610	COG0251	oxidation-reduction process
KPA27_RS03615	COG1660	Displays ATPase and GTPase activities
KPA27_RS03620	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KPA27_RS03625	COG1481	regulation of sporulation
KPA27_RS03640	COG0454	-acetyltransferase
KPA27_RS03645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KPA27_RS03650	COG0549	Belongs to the carbamate kinase family
KPA27_RS03655	COG1288	antiporter activity
KPA27_RS03660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KPA27_RS03670	COG1438	arginine binding
KPA27_RS03675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KPA27_RS03680	COG0363	glucosamine-6-phosphate deaminase activity
KPA27_RS03705	COG1696	Membrane protein involved in D-alanine export
KPA27_RS03710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPA27_RS03725	COG0435	Glutathione S-transferase
KPA27_RS03730	COG1187	pseudouridine synthase activity
KPA27_RS03735	COG0386	Belongs to the glutathione peroxidase family
KPA27_RS03740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPA27_RS03745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPA27_RS03750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPA27_RS03755	COG1120	ATPase activity
KPA27_RS03760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPA27_RS03765	COG0204	Acyl-transferase
KPA27_RS03770	COG1555	photosystem II stabilization
KPA27_RS03770	COG1596	polysaccharide export
KPA27_RS03775	COG0658	competence protein
KPA27_RS03775	COG2333	competence protein COMEC
KPA27_RS03780	COG1466	dna polymerase III delta subunit
KPA27_RS03785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KPA27_RS03790	COG0737	Belongs to the 5'-nucleotidase family
KPA27_RS03800	COG0038	chloride channel
KPA27_RS03805	COG0287	Prephenate dehydrogenase
KPA27_RS03805	COG1605	Chorismate mutase
KPA27_RS03815	COG0716	FMN binding
KPA27_RS03820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KPA27_RS03835	COG0772	Belongs to the SEDS family
KPA27_RS03840	COG0693	protein deglycase activity
KPA27_RS03845	COG0187	DNA topoisomerase II activity
KPA27_RS03850	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KPA27_RS03855	COG0560	Phosphoserine phosphatase
KPA27_RS03895	COG1011	Hydrolase
KPA27_RS03905	COG2706	6-phosphogluconolactonase activity
KPA27_RS03910	COG0628	permease
KPA27_RS03920	COG3527	Alpha-acetolactate decarboxylase
KPA27_RS03925	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KPA27_RS03940	COG3842	ATPase activity
KPA27_RS03985	COG0488	(ABC) transporter
KPA27_RS03995	COG2226	methyltransferase
KPA27_RS04000	COG3442	glutamine amidotransferase
KPA27_RS04005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KPA27_RS04020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPA27_RS04025	COG0488	(ABC) transporter
KPA27_RS04030	COG2226	methyltransferase
KPA27_RS04055	COG1573	uracil-dna glycosylase
KPA27_RS04065	COG1704	LemA family
KPA27_RS04070	COG2268	Band 7 protein
KPA27_RS04085	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KPA27_RS04095	COG1204	response to ionizing radiation
KPA27_RS04100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KPA27_RS04105	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KPA27_RS04110	COG1393	Belongs to the ArsC family
KPA27_RS04115	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KPA27_RS04125	COG0813	purine-nucleoside phosphorylase activity
KPA27_RS04130	COG0058	SHG alpha-glucan phosphorylase activity
KPA27_RS04140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KPA27_RS04150	COG1051	belongs to the nudix hydrolase family
KPA27_RS04155	COG0647	UMP catabolic process
KPA27_RS04165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KPA27_RS04170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KPA27_RS04175	COG1970	mechanosensitive ion channel activity
KPA27_RS04180	COG0358	DNA primase activity
KPA27_RS04185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPA27_RS04190	COG2151	metal-sulfur cluster biosynthetic enzyme
KPA27_RS04195	COG1982	Orn Lys Arg decarboxylase major
KPA27_RS04200	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KPA27_RS04245	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KPA27_RS04255	COG1131	(ABC) transporter
KPA27_RS04260	COG2188	Transcriptional regulator
KPA27_RS04270	COG0205	6-phosphofructokinase activity
KPA27_RS04275	COG0469	pyruvate kinase activity
KPA27_RS04305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPA27_RS04310	COG2755	lipolytic protein G-D-S-L family
KPA27_RS04310	COG0657	acetylesterase activity
KPA27_RS04320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KPA27_RS04325	COG0765	amino acid transport
KPA27_RS04330	COG1126	abc transporter atp-binding protein
KPA27_RS04335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPA27_RS04340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPA27_RS04355	COG1846	Transcriptional regulator
KPA27_RS04360	COG3759	membrane
KPA27_RS04385	COG2195	Cleaves the N-terminal amino acid of tripeptides
KPA27_RS04390	COG0561	phosphatase activity
KPA27_RS04425	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KPA27_RS04430	COG0196	riboflavin kinase activity
KPA27_RS04435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KPA27_RS04440	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS04445	COG1393	Belongs to the ArsC family
KPA27_RS04450	COG4476	Belongs to the UPF0223 family
KPA27_RS04455	COG0483	inositol monophosphate 1-phosphatase activity
KPA27_RS04470	COG0573	inorganic phosphate transmembrane transporter activity
KPA27_RS04475	COG0581	inorganic phosphate transmembrane transporter activity
KPA27_RS04480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KPA27_RS04485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KPA27_RS04490	COG0704	Plays a role in the regulation of phosphate uptake
KPA27_RS04500	COG0745	RESPONSE REGULATOR receiver
KPA27_RS04505	COG5002	protein histidine kinase activity
KPA27_RS04515	COG0268	Binds directly to 16S ribosomal RNA
KPA27_RS04520	COG1072	(Pantothenic acid kinase))
KPA27_RS04525	COG2813	Specifically methylates the guanine in position
KPA27_RS04530	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KPA27_RS04540	COG0295	cytidine deaminase activity
KPA27_RS04545	COG1744	ABC transporter substrate-binding protein PnrA-like
KPA27_RS04550	COG3845	ABC transporter
KPA27_RS04555	COG4603	Belongs to the binding-protein-dependent transport system permease family
KPA27_RS04560	COG1079	Belongs to the binding-protein-dependent transport system permease family
KPA27_RS04565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPA27_RS04570	COG0039	L-malate dehydrogenase activity
KPA27_RS04575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPA27_RS04580	COG3764	Sortase (surface protein transpeptidase)
KPA27_RS04590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KPA27_RS04595	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KPA27_RS04610	COG1104	cysteine desulfurase activity
KPA27_RS04620	COG4116	CYTH
KPA27_RS04625	COG2357	RelA SpoT domain protein
KPA27_RS04630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KPA27_RS04635	COG0564	pseudouridine synthase activity
KPA27_RS04640	COG0280	phosphate acetyltransferase
KPA27_RS04645	COG1132	(ABC) transporter
KPA27_RS04650	COG1132	(ABC) transporter
KPA27_RS04660	COG1194	a g-specific adenine glycosylase
KPA27_RS04665	COG1396	sequence-specific DNA binding
KPA27_RS04685	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS04700	COG1349	DNA-binding transcription factor activity
KPA27_RS04705	COG0698	ribose 5-phosphate isomerase
KPA27_RS04710	COG0698	ribose 5-phosphate isomerase
KPA27_RS04715	COG1105	Belongs to the carbohydrate kinase PfkB family
KPA27_RS04735	COG3775	system Galactitol-specific IIC component
KPA27_RS04745	COG3711	transcriptional antiterminator
KPA27_RS04755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPA27_RS04755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPA27_RS04780	COG2873	o-acetylhomoserine
KPA27_RS04785	COG0488	(ABC) transporter
KPA27_RS04795	COG1126	abc transporter atp-binding protein
KPA27_RS04810	COG3583	domain protein
KPA27_RS04825	COG4978	Transcriptional regulator
KPA27_RS04825	COG0789	Transcriptional regulator
KPA27_RS04845	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KPA27_RS04850	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KPA27_RS04855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KPA27_RS04860	COG1882	Formate acetyltransferase
KPA27_RS04865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPA27_RS04895	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
KPA27_RS04900	COG4766	ethanolamine catabolic process
KPA27_RS04910	COG1454	alcohol dehydrogenase
KPA27_RS04910	COG1012	belongs to the aldehyde dehydrogenase family
KPA27_RS04915	COG4869	propanediol catabolic process
KPA27_RS04945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPA27_RS04950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPA27_RS04960	COG0297	glycogen (starch) synthase activity
KPA27_RS04970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KPA27_RS04985	COG0167	dihydroorotate dehydrogenase activity
KPA27_RS04990	COG0284	orotidine-5'-phosphate decarboxylase activity
KPA27_RS05005	COG0463	Glycosyl transferase, family 2
KPA27_RS05010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPA27_RS05020	COG0737	Belongs to the 5'-nucleotidase family
KPA27_RS05025	COG0424	maF-like protein
KPA27_RS05035	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KPA27_RS05040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPA27_RS05050	COG1272	protein, Hemolysin III
KPA27_RS05060	COG0446	pyridine nucleotide-disulphide oxidoreductase
KPA27_RS05065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPA27_RS05070	COG1937	Protein conserved in bacteria
KPA27_RS05075	COG0110	maltose O-acetyltransferase activity
KPA27_RS05080	COG0758	DNA mediated transformation
KPA27_RS05085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPA27_RS05090	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS05095	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPA27_RS05100	COG0222	ribosome binding
KPA27_RS05105	COG0647	UMP catabolic process
KPA27_RS05110	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KPA27_RS05150	COG1136	(ABC) transporter
KPA27_RS05155	COG0577	efflux transmembrane transporter activity
KPA27_RS05170	COG0745	RESPONSE REGULATOR receiver
KPA27_RS05185	COG4974	Belongs to the 'phage' integrase family
KPA27_RS05190	COG1660	Displays ATPase and GTPase activities
KPA27_RS05205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KPA27_RS05210	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KPA27_RS05215	COG2188	Transcriptional regulator
KPA27_RS05225	COG4268	DNA restriction-modification system
KPA27_RS05230	COG1401	restriction endodeoxyribonuclease activity
KPA27_RS05255	COG4221	oxidoreductase activity
KPA27_RS05260	COG0741	lytic transglycosylase activity
KPA27_RS05270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KPA27_RS05280	COG0009	L-threonylcarbamoyladenylate synthase
KPA27_RS05285	COG2890	protein-(glutamine-N5) methyltransferase activity
KPA27_RS05290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPA27_RS05315	COG0481	GTPase activity
KPA27_RS05330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KPA27_RS05335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPA27_RS05340	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KPA27_RS05355	COG1940	carbohydrate kinase activity
KPA27_RS05365	COG0488	(ABC) transporter
KPA27_RS05370	COG0617	tRNA 3'-terminal CCA addition
KPA27_RS05375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KPA27_RS05380	COG1307	EDD domain protein, DegV family
KPA27_RS05390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KPA27_RS05390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KPA27_RS05390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPA27_RS05395	COG1105	Belongs to the carbohydrate kinase PfkB family
KPA27_RS05400	COG1349	DNA-binding transcription factor activity
KPA27_RS05405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KPA27_RS05410	COG0336	Belongs to the RNA methyltransferase TrmD family
KPA27_RS05415	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KPA27_RS05420	COG0534	Mate efflux family protein
KPA27_RS05430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPA27_RS05435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KPA27_RS05450	COG1177	transmembrane transport
KPA27_RS05455	COG1176	ABC-type spermidine putrescine transport system, permease component I
KPA27_RS05465	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KPA27_RS05470	COG0083	homoserine kinase activity
KPA27_RS05475	COG0460	homoserine dehydrogenase
KPA27_RS05480	COG0726	polysaccharide deacetylase
KPA27_RS05490	COG1132	(ABC) transporter
KPA27_RS05505	COG0228	four-way junction DNA binding
KPA27_RS05520	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KPA27_RS05525	COG2136	Putative SAM-dependent methyltransferase
KPA27_RS05525	COG2521	methyltransferase
KPA27_RS05545	COG0505	Belongs to the CarA family
KPA27_RS05550	COG0540	Belongs to the ATCase OTCase family
KPA27_RS05555	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPA27_RS05565	COG2824	Alkylphosphonate utilization operon protein PhnA
KPA27_RS05570	COG0564	pseudouridine synthase activity
KPA27_RS05590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KPA27_RS05595	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KPA27_RS05600	COG1114	Component of the transport system for branched-chain amino acids
KPA27_RS05605	COG0301	tRNA thio-modification
KPA27_RS05610	COG1104	cysteine desulfurase activity
KPA27_RS05680	COG0539	negative regulation of cytoplasmic translation
KPA27_RS05700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KPA27_RS05710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPA27_RS05720	COG2184	nucleotidyltransferase activity
KPA27_RS05725	COG0187	DNA topoisomerase II activity
KPA27_RS05735	COG1074	ATP-dependent DNA helicase activity
KPA27_RS05740	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KPA27_RS05770	COG1131	(ABC) transporter
KPA27_RS05800	COG1011	Hydrolase
KPA27_RS05810	COG0210	DNA helicase
KPA27_RS05825	COG1164	Oligoendopeptidase f
KPA27_RS05835	COG0346	lactoylglutathione lyase activity
KPA27_RS05840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KPA27_RS05845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KPA27_RS05850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KPA27_RS05860	COG0446	pyridine nucleotide-disulphide oxidoreductase
KPA27_RS05865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPA27_RS05870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPA27_RS05890	COG1882	Formate acetyltransferase
KPA27_RS05895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPA27_RS05900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPA27_RS05905	COG1447	Phosphotransferase system cellobiose-specific component IIA
KPA27_RS05915	COG1349	DNA-binding transcription factor activity
KPA27_RS05920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPA27_RS05955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPA27_RS05965	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KPA27_RS05975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPA27_RS05980	COG4684	Psort location CytoplasmicMembrane, score
KPA27_RS05985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPA27_RS06045	COG1131	(ABC) transporter
KPA27_RS06070	COG3843	relaxase mobilization nuclease domain protein
KPA27_RS06085	COG0613	PHP domain protein
KPA27_RS06090	COG0542	response to heat
KPA27_RS06095	COG1396	sequence-specific DNA binding
KPA27_RS06150	COG4443	Transcriptional Coactivator p15 (PC4)
KPA27_RS06155	COG1475	DNA binding
KPA27_RS06325	COG0270	DNA (cytosine-5-)-methyltransferase activity
KPA27_RS06340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPA27_RS06350	COG0077	Prephenate dehydratase
KPA27_RS06355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KPA27_RS06365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KPA27_RS06370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KPA27_RS06375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPA27_RS06380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KPA27_RS06385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KPA27_RS06385	COG1116	anion transmembrane transporter activity
KPA27_RS06390	COG4120	Belongs to the binding-protein-dependent transport system permease family
KPA27_RS06405	COG3684	Belongs to the aldolase LacD family
KPA27_RS06415	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS06420	COG3679	Belongs to the UPF0342 family
KPA27_RS06425	COG0287	Prephenate dehydrogenase
KPA27_RS06430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KPA27_RS06435	COG0710	3-dehydroquinate dehydratase activity
KPA27_RS06440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KPA27_RS06445	COG1368	sulfuric ester hydrolase activity
KPA27_RS06460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KPA27_RS06470	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KPA27_RS06500	COG1216	Glycosyl transferase, family 2
KPA27_RS06515	COG1442	glycosyl transferase family 8
KPA27_RS06515	COG1216	Glycosyl transferase, family 2
KPA27_RS06520	COG1442	glycosyl transferase family 8
KPA27_RS06550	COG1216	Glycosyl transferase, family 2
KPA27_RS06550	COG1442	glycosyl transferase family 8
KPA27_RS06580	COG1091	dTDP-4-dehydrorhamnose reductase activity
KPA27_RS06585	COG1088	dTDP-glucose 4,6-dehydratase activity
KPA27_RS06600	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KPA27_RS06610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KPA27_RS06615	COG2384	SAM-dependent methyltransferase
KPA27_RS06630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPA27_RS06640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KPA27_RS06640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KPA27_RS06645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPA27_RS06655	COG0300	oxidoreductase activity
KPA27_RS06660	COG1234	tRNA 3'-trailer cleavage
KPA27_RS06670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPA27_RS06675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPA27_RS06685	COG2807	transmembrane transport
KPA27_RS06690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPA27_RS06700	COG2610	gluconate transmembrane transporter activity
KPA27_RS06720	COG0302	gtp cyclohydrolase
KPA27_RS06725	COG1051	belongs to the nudix hydrolase family
KPA27_RS06750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPA27_RS06750	COG0072	phenylalanine-tRNA ligase activity
KPA27_RS06770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPA27_RS06780	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KPA27_RS06785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPA27_RS06790	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPA27_RS06795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPA27_RS06800	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPA27_RS06805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KPA27_RS06810	COG0356	it plays a direct role in the translocation of protons across the membrane
KPA27_RS06820	COG1597	lipid kinase activity
KPA27_RS06835	COG0701	Predicted permease
KPA27_RS06840	COG3689	TIGRFAM TIGR03943 family protein
KPA27_RS06845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KPA27_RS06860	COG0552	protein localization to endoplasmic reticulum
KPA27_RS06865	COG0561	phosphatase activity
KPA27_RS06875	COG1196	nuclear chromosome segregation
KPA27_RS06910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPA27_RS06915	COG0538	isocitrate dehydrogenase activity
KPA27_RS06920	COG0372	Belongs to the citrate synthase family
KPA27_RS06925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KPA27_RS06930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KPA27_RS06935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPA27_RS06940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPA27_RS06975	COG1476	TRANSCRIPTIONal
KPA27_RS06995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPA27_RS07005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KPA27_RS07010	COG4122	O-methyltransferase activity
KPA27_RS07040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPA27_RS07040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPA27_RS07070	COG0531	amino acid
KPA27_RS07080	COG0708	Exodeoxyribonuclease III
KPA27_RS07095	COG1393	Belongs to the ArsC family
KPA27_RS07100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPA27_RS07105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KPA27_RS07115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KPA27_RS07125	COG4467	Involved in initiation control of chromosome replication
KPA27_RS07130	COG0470	DNA polymerase III
KPA27_RS07135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPA27_RS07140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPA27_RS07155	COG0517	IMP dehydrogenase activity
KPA27_RS07185	COG0683	leucine binding
KPA27_RS07200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KPA27_RS07205	COG0366	Alpha amylase catalytic
KPA27_RS07215	COG0395	ABC-type sugar transport system, permease component
KPA27_RS07220	COG1175	transmembrane transport
KPA27_RS07225	COG1653	transport
KPA27_RS07235	COG2207	Transcriptional regulator
KPA27_RS07240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KPA27_RS07245	COG0626	cystathionine gamma-synthase activity
KPA27_RS07265	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KPA27_RS07270	COG2827	Endonuclease containing a URI domain
KPA27_RS07285	COG0513	Belongs to the DEAD box helicase family
KPA27_RS07290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPA27_RS07315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KPA27_RS07325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KPA27_RS07345	COG1181	Belongs to the D-alanine--D-alanine ligase family
KPA27_RS07350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPA27_RS07355	COG0768	penicillin binding
KPA27_RS07360	COG0488	(ABC) transporter
KPA27_RS07365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KPA27_RS07375	COG0745	RESPONSE REGULATOR receiver
KPA27_RS07385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPA27_RS07390	COG0765	amino acid transport
KPA27_RS07395	COG0765	amino acid transport
KPA27_RS07400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPA27_RS07415	COG0438	transferase activity, transferring glycosyl groups
KPA27_RS07425	COG1609	Transcriptional regulator
KPA27_RS07435	COG0343	queuine tRNA-ribosyltransferase activity
KPA27_RS07445	COG1832	CoA-binding protein
KPA27_RS07455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPA27_RS07455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPA27_RS07470	COG1136	(ABC) transporter
KPA27_RS07480	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KPA27_RS07485	COG2217	Heavy metal translocating P-type atpase
KPA27_RS07500	COG1063	alcohol dehydrogenase
KPA27_RS07520	COG1122	ATPase activity
KPA27_RS07530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KPA27_RS07535	COG0557	exoribonuclease II activity
KPA27_RS07545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KPA27_RS07550	COG2814	Major facilitator Superfamily
KPA27_RS07560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KPA27_RS07565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KPA27_RS07570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KPA27_RS07580	COG1737	Transcriptional regulator
KPA27_RS07600	COG1011	Hydrolase
KPA27_RS07605	COG1132	(ABC) transporter
KPA27_RS07610	COG1132	(ABC) transporter
KPA27_RS07620	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS07640	COG2177	Part of the ABC transporter FtsEX involved in
KPA27_RS07645	COG2884	Cell division ATP-binding protein ftsE
KPA27_RS07655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KPA27_RS07690	COG1078	dGTPase activity
KPA27_RS07700	COG0149	triose-phosphate isomerase activity
KPA27_RS07705	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPA27_RS07720	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KPA27_RS07725	COG0772	Belongs to the SEDS family
KPA27_RS07745	COG3859	Proton-coupled thiamine transporter YuaJ
KPA27_RS07755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KPA27_RS07765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KPA27_RS07775	COG0577	efflux transmembrane transporter activity
KPA27_RS07780	COG1136	(ABC) transporter
KPA27_RS07785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KPA27_RS07790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPA27_RS07795	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KPA27_RS07800	COG1268	BioY protein
KPA27_RS07810	COG3833	ABC-type maltose transport systems, permease component
KPA27_RS07815	COG1175	transmembrane transport
KPA27_RS07830	COG1609	Transcriptional regulator
KPA27_RS07840	COG4443	Transcriptional Coactivator p15 (PC4)
KPA27_RS07850	COG0826	peptidase U32
KPA27_RS07865	COG0789	Transcriptional regulator
KPA27_RS07875	COG1227	inorganic diphosphatase activity
KPA27_RS07890	COG1733	regulation of RNA biosynthetic process
KPA27_RS07895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KPA27_RS07900	COG2514	catechol 2,3-dioxygenase activity
KPA27_RS07910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPA27_RS07915	COG1253	flavin adenine dinucleotide binding
KPA27_RS07920	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS07925	COG1119	ATPase activity
KPA27_RS07930	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KPA27_RS07950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPA27_RS07955	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KPA27_RS07960	COG0133	tryptophan synthase activity
KPA27_RS07975	COG4470	Protein conserved in bacteria
KPA27_RS07980	COG3480	Lon protease (S16) C-terminal proteolytic domain
KPA27_RS07985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KPA27_RS07990	COG0742	ribosomal rna small subunit methyltransferase
KPA27_RS08000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPA27_RS08005	COG4483	Protein conserved in bacteria
KPA27_RS08010	COG2197	response regulator
KPA27_RS08015	COG4585	Histidine kinase
KPA27_RS08020	COG0842	Transport permease protein
KPA27_RS08025	COG1131	(ABC) transporter
KPA27_RS08040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPA27_RS08050	COG2755	lipolytic protein G-D-S-L family
KPA27_RS08050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KPA27_RS08055	COG0671	phosphoesterase, PA-phosphatase related
KPA27_RS08060	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPA27_RS08070	COG0747	negative chemotaxis
KPA27_RS08075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KPA27_RS08080	COG1187	pseudouridine synthase activity
KPA27_RS08085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPA27_RS08090	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPA27_RS08095	COG0582	viral genome integration into host DNA
KPA27_RS08115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KPA27_RS08120	COG3763	UPF0154 protein
KPA27_RS08130	COG3579	cysteine-type endopeptidase activity
KPA27_RS08145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPA27_RS08150	COG1254	Belongs to the acylphosphatase family
KPA27_RS08160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KPA27_RS08165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KPA27_RS08175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KPA27_RS08185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KPA27_RS08200	COG1160	GTP binding
KPA27_RS08210	COG1484	DNA-dependent DNA replication
KPA27_RS08220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPA27_RS08225	COG0628	permease
KPA27_RS08230	COG0745	RESPONSE REGULATOR receiver
KPA27_RS08235	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KPA27_RS08245	COG0492	ferredoxin-NADP+ reductase activity
KPA27_RS08255	COG0513	Belongs to the DEAD box helicase family
KPA27_RS08270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPA27_RS08275	COG0768	penicillin binding
KPA27_RS08285	COG0275	rRNA processing
KPA27_RS08335	COG4939	FMN-binding domain protein
KPA27_RS08340	COG0142	geranyltranstransferase activity
KPA27_RS08345	COG1252	NADH dehydrogenase
KPA27_RS08355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KPA27_RS08360	COG0569	domain protein
KPA27_RS08365	COG0534	Mate efflux family protein
KPA27_RS08375	COG4224	UPF0291 protein
KPA27_RS08380	COG0751	glycine-tRNA ligase activity
KPA27_RS08405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KPA27_RS08410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KPA27_RS08415	COG1464	Belongs to the NlpA lipoprotein family
KPA27_RS08420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KPA27_RS08425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPA27_RS08430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KPA27_RS08435	COG2252	PERMEase
KPA27_RS08440	COG0561	phosphatase activity
KPA27_RS08445	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS08455	COG3715	PTS system
KPA27_RS08460	COG3716	PTS system mannose fructose sorbose family IID component
KPA27_RS08475	COG1983	PspC domain protein
KPA27_RS08480	COG1266	CAAX protease self-immunity
KPA27_RS08500	COG0439	Biotin carboxylase
KPA27_RS08520	COG1028	Short-chain dehydrogenase reductase Sdr
KPA27_RS08525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KPA27_RS08530	COG2070	2-Nitropropane dioxygenase
KPA27_RS08540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPA27_RS08550	COG1024	Enoyl-CoA hydratase
KPA27_RS08555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KPA27_RS08560	COG0527	aspartate kinase activity
KPA27_RS08565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPA27_RS08570	COG0736	holo-[acyl-carrier-protein] synthase activity
KPA27_RS08575	COG0653	protein targeting
KPA27_RS08580	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS08585	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KPA27_RS08585	COG3583	domain protein
KPA27_RS08590	COG1940	carbohydrate kinase activity
KPA27_RS08600	COG1263	PTS System
KPA27_RS08600	COG2190	(PTS) system
KPA27_RS08600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPA27_RS08605	COG1621	beta-fructofuranosidase activity
KPA27_RS08610	COG1609	Transcriptional regulator
KPA27_RS08615	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPA27_RS08630	COG0006	proline dipeptidase activity
KPA27_RS08655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KPA27_RS08670	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KPA27_RS08675	COG0629	single-stranded DNA binding
KPA27_RS08685	COG0095	Lipoate-protein ligase
KPA27_RS08690	COG2723	6-phospho-beta-galactosidase activity
KPA27_RS08705	COG2723	6-phospho-beta-galactosidase activity
KPA27_RS08710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPA27_RS08720	COG1447	Phosphotransferase system cellobiose-specific component IIA
KPA27_RS08725	COG3711	transcriptional antiterminator
KPA27_RS08725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPA27_RS08740	COG4095	Psort location CytoplasmicMembrane, score
KPA27_RS08745	COG2723	6-phospho-beta-galactosidase activity
KPA27_RS08750	COG2723	6-phospho-beta-galactosidase activity
KPA27_RS08755	COG1917	Cupin 2, conserved barrel domain protein
KPA27_RS08755	COG2207	Transcriptional regulator
KPA27_RS08765	COG2190	(PTS) system
KPA27_RS08765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPA27_RS08765	COG1263	PTS System
KPA27_RS08770	COG3711	transcriptional antiterminator
KPA27_RS08785	COG0508	dehydrogenase complex catalyzes the overall conversion of
KPA27_RS08790	COG0508	dehydrogenase complex catalyzes the overall conversion of
KPA27_RS08790	COG0022	dehydrogenase e1 component
KPA27_RS08795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KPA27_RS08800	COG2860	membrane
KPA27_RS08815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KPA27_RS08820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPA27_RS08830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KPA27_RS08835	COG0195	Participates in both transcription termination and antitermination
KPA27_RS08845	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KPA27_RS08855	COG4473	ABC transporter
KPA27_RS08860	COG1131	(ABC) transporter
KPA27_RS08865	COG0537	adenosine 5'-monophosphoramidase activity
KPA27_RS08875	COG1316	TRANSCRIPTIONal
KPA27_RS08885	COG0802	atpase or kinase
KPA27_RS08890	COG1461	Dihydroxyacetone kinase
KPA27_RS08900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPA27_RS08905	COG0601	transmembrane transport
KPA27_RS08910	COG4608	Belongs to the ABC transporter superfamily
KPA27_RS08925	COG1686	Belongs to the peptidase S11 family
KPA27_RS08940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KPA27_RS08945	COG0719	Fe-S assembly protein
KPA27_RS08955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPA27_RS08960	COG4862	establishment of competence for transformation
KPA27_RS08965	COG1968	undecaprenyl-diphosphatase activity
KPA27_RS08970	COG0765	amino acid transport
KPA27_RS08990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KPA27_RS08995	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KPA27_RS09000	COG0440	acetolactate synthase activity
KPA27_RS09005	COG0028	Belongs to the TPP enzyme family
KPA27_RS09010	COG0463	Glycosyl transferase, family 2
KPA27_RS09020	COG0129	dihydroxy-acid dehydratase activity
KPA27_RS09030	COG2151	metal-sulfur cluster biosynthetic enzyme
KPA27_RS09090	COG1442	glycosyl transferase family 8
KPA27_RS09090	COG1216	Glycosyl transferase, family 2
KPA27_RS09105	COG1216	Glycosyl transferase, family 2
KPA27_RS09105	COG1442	glycosyl transferase family 8
KPA27_RS09115	COG1442	glycosyl transferase family 8
KPA27_RS09160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPA27_RS09180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPA27_RS09205	COG3842	ATPase activity
KPA27_RS09215	COG2207	Transcriptional regulator
KPA27_RS09215	COG4753	response regulator
KPA27_RS09220	COG2972	Histidine kinase
KPA27_RS09230	COG1653	transport
KPA27_RS09235	COG0395	ABC-type sugar transport system, permease component
KPA27_RS09240	COG1175	transmembrane transport
KPA27_RS09255	COG0383	alpha-mannosidase activity
KPA27_RS09275	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KPA27_RS09295	COG1045	serine acetyltransferase
KPA27_RS09300	COG1185	polyribonucleotide nucleotidyltransferase activity
KPA27_RS09305	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KPA27_RS09335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPA27_RS09340	COG1187	pseudouridine synthase activity
KPA27_RS09360	COG0242	peptide deformylase activity
KPA27_RS09390	COG0066	3-isopropylmalate dehydratase activity
KPA27_RS09415	COG2309	aminopeptidase activity
KPA27_RS09425	COG2176	DNA-directed DNA polymerase activity
KPA27_RS09445	COG2376	Dihydroxyacetone kinase
KPA27_RS09455	COG2376	Dihydroxyacetone kinase
KPA27_RS09460	COG1461	Dihydroxyacetone kinase
KPA27_RS09465	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
KPA27_RS09470	COG0442	prolyl-tRNA aminoacylation
KPA27_RS09480	COG4589	Belongs to the CDS family
KPA27_RS09485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KPA27_RS09490	COG1862	Preprotein translocase
KPA27_RS09500	COG2918	glutathione biosynthetic process
KPA27_RS09500	COG1181	Belongs to the D-alanine--D-alanine ligase family
KPA27_RS09510	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KPA27_RS09515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPA27_RS09520	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KPA27_RS09525	COG0542	response to heat
KPA27_RS09530	COG4463	regulation of RNA biosynthetic process
KPA27_RS09545	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KPA27_RS09585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KPA27_RS09590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPA27_RS09595	COG0492	ferredoxin-NADP+ reductase activity
KPA27_RS09600	COG0564	pseudouridine synthase activity
KPA27_RS09605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPA27_RS09625	COG1564	THIamine pyrophosphokinase
KPA27_RS09635	COG1162	GTPase activity
KPA27_RS09645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KPA27_RS09650	COG1132	(ABC) transporter
KPA27_RS09700	COG0084	hydrolase, TatD family'
KPA27_RS09710	COG1847	R3H domain protein
KPA27_RS09720	COG0594	ribonuclease P activity
KPA27_RS09725	COG0165	Argininosuccinate lyase
KPA27_RS09730	COG0137	argininosuccinate synthase activity
KPA27_RS09740	COG1827	regulation of RNA biosynthetic process
KPA27_RS09755	COG2040	homocysteine
KPA27_RS09760	COG0833	amino acid
KPA27_RS09770	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS09800	COG1442	glycosyl transferase family 8
KPA27_RS09825	COG0756	dUTP diphosphatase activity
KPA27_RS09830	COG1132	(ABC) transporter
KPA27_RS09835	COG1132	(ABC) transporter
KPA27_RS09845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KPA27_RS09850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KPA27_RS09855	COG0705	Rhomboid family
KPA27_RS09860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KPA27_RS09865	COG1473	amidohydrolase
KPA27_RS09870	COG2171	N-acyltransferase activity
KPA27_RS09880	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KPA27_RS09895	COG1442	glycosyl transferase family 8
KPA27_RS09920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KPA27_RS09945	COG3623	hexulose-6-phosphate isomerase
KPA27_RS09970	COG1523	belongs to the glycosyl hydrolase 13 family
KPA27_RS09975	COG1609	Transcriptional regulator
KPA27_RS09980	COG1126	abc transporter atp-binding protein
KPA27_RS09985	COG0765	amino acid transport
KPA27_RS09990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPA27_RS10000	COG3942	CHAP domain
KPA27_RS10010	COG4667	esterase of the alpha-beta hydrolase superfamily
KPA27_RS10015	COG3590	peptidase
KPA27_RS10020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KPA27_RS10025	COG1321	iron dependent repressor
KPA27_RS10025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KPA27_RS10030	COG1121	(ABC) transporter
KPA27_RS10035	COG0803	Belongs to the bacterial solute-binding protein 9 family
KPA27_RS10050	COG1490	D-aminoacyl-tRNA deacylase activity
KPA27_RS10060	COG0737	Belongs to the 5'-nucleotidase family
KPA27_RS10070	COG1811	Na channel or pump
KPA27_RS10075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KPA27_RS10100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KPA27_RS10125	COG0737	Belongs to the 5'-nucleotidase family
KPA27_RS10135	COG1328	CTP reductase activity
KPA27_RS10140	COG1126	abc transporter atp-binding protein
KPA27_RS10150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPA27_RS10155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KPA27_RS10175	COG1438	arginine binding
KPA27_RS10180	COG0018	arginyl-trna synthetase
KPA27_RS10195	COG2826	transposase and inactivated derivatives, IS30 family
KPA27_RS10205	COG1640	4-alpha-glucanotransferase
KPA27_RS10210	COG2182	Extracellular solute-binding protein
KPA27_RS10215	COG1175	transmembrane transport
KPA27_RS10220	COG3833	ABC-type maltose transport systems, permease component
KPA27_RS10225	COG5521	maltodextrose utilization protein MalA
KPA27_RS10230	COG1609	Transcriptional regulator
KPA27_RS10235	COG1523	belongs to the glycosyl hydrolase 13 family
KPA27_RS10240	COG1780	Probably involved in ribonucleotide reductase function
KPA27_RS10245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPA27_RS10250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KPA27_RS10255	COG2153	protein acetylation
KPA27_RS10260	COG4989	oxidoreductase activity
KPA27_RS10265	COG1216	Glycosyl transferase, family 2
KPA27_RS10270	COG1472	Belongs to the glycosyl hydrolase 3 family
KPA27_RS10315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPA27_RS10325	COG0305	Participates in initiation and elongation during chromosome replication
KPA27_RS10330	COG0359	binds to the 23S rRNA
KPA27_RS10340	COG0445	tRNA wobble uridine modification
KPA27_RS10345	COG0494	nUDIX hydrolase
KPA27_RS10350	COG1733	regulation of RNA biosynthetic process
KPA27_RS10365	COG0482	sulfurtransferase activity
KPA27_RS10370	COG1760	l-serine dehydratase
KPA27_RS10375	COG1760	l-serine dehydratase
KPA27_RS10385	COG0745	RESPONSE REGULATOR receiver
KPA27_RS10390	COG3850	Histidine kinase
KPA27_RS10390	COG5002	protein histidine kinase activity
KPA27_RS10400	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPA27_RS10405	COG1122	ATPase activity
KPA27_RS10410	COG1122	ATPase activity
KPA27_RS10415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPA27_RS10420	COG1426	Protein conserved in bacteria
KPA27_RS10425	COG0612	Peptidase, M16
KPA27_RS10430	COG0612	Peptidase, M16
KPA27_RS10440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPA27_RS10445	COG0516	GMP reductase activity
KPA27_RS10445	COG0517	IMP dehydrogenase activity
KPA27_RS10455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPA27_RS10460	COG0488	(ABC) transporter
KPA27_RS10490	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPA27_RS10495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPA27_RS10500	COG1475	DNA binding