locus-tag	class	description
AN924_RS00005	COG1072	(Pantothenic acid kinase))
AN924_RS00010	COG0268	Binds directly to 16S ribosomal RNA
AN924_RS00020	COG5002	protein histidine kinase activity
AN924_RS00025	COG0745	RESPONSE REGULATOR receiver
AN924_RS00040	COG0704	Plays a role in the regulation of phosphate uptake
AN924_RS00045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN924_RS00050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN924_RS00055	COG0581	inorganic phosphate transmembrane transporter activity
AN924_RS00060	COG0573	inorganic phosphate transmembrane transporter activity
AN924_RS00070	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AN924_RS00070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AN924_RS00075	COG0483	inositol monophosphate 1-phosphatase activity
AN924_RS00080	COG4476	Belongs to the UPF0223 family
AN924_RS00085	COG1393	Belongs to the ArsC family
AN924_RS00090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN924_RS00100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AN924_RS00140	COG0561	phosphatase activity
AN924_RS00145	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN924_RS00160	COG1695	Transcriptional regulator
AN924_RS00180	COG3759	membrane
AN924_RS00185	COG1846	Transcriptional regulator
AN924_RS00200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN924_RS00205	COG2610	gluconate transmembrane transporter activity
AN924_RS00225	COG0302	gtp cyclohydrolase
AN924_RS00230	COG1051	belongs to the nudix hydrolase family
AN924_RS00255	COG0072	phenylalanine-tRNA ligase activity
AN924_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN924_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
AN924_RS00290	COG1312	Catalyzes the dehydration of D-mannonate
AN924_RS00300	COG0800	Aldolase
AN924_RS00310	COG3250	beta-galactosidase activity
AN924_RS00320	COG2211	Major facilitator Superfamily
AN924_RS00335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN924_RS00345	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AN924_RS00350	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AN924_RS00355	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AN924_RS00360	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AN924_RS00365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AN924_RS00370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AN924_RS00375	COG0356	it plays a direct role in the translocation of protons across the membrane
AN924_RS00385	COG1597	lipid kinase activity
AN924_RS00395	COG0701	Predicted permease
AN924_RS00400	COG3689	TIGRFAM TIGR03943 family protein
AN924_RS00405	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AN924_RS00420	COG0552	protein localization to endoplasmic reticulum
AN924_RS00425	COG0561	phosphatase activity
AN924_RS00430	COG0561	phosphatase activity
AN924_RS00435	COG1196	nuclear chromosome segregation
AN924_RS00470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN924_RS00475	COG0538	isocitrate dehydrogenase activity
AN924_RS00480	COG0372	Belongs to the citrate synthase family
AN924_RS00485	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AN924_RS00490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN924_RS00495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN924_RS00500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN924_RS00505	COG1609	Transcriptional regulator
AN924_RS00520	COG5492	domain, Protein
AN924_RS00530	COG3716	PTS system mannose fructose sorbose family IID component
AN924_RS00540	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN924_RS00545	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AN924_RS00570	COG1028	Short-chain dehydrogenase reductase Sdr
AN924_RS00605	COG1476	TRANSCRIPTIONal
AN924_RS00625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AN924_RS00635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN924_RS00640	COG4122	O-methyltransferase activity
AN924_RS00665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN924_RS00665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN924_RS00675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN924_RS00680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN924_RS00685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AN924_RS00690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AN924_RS00695	COG1116	anion transmembrane transporter activity
AN924_RS00695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN924_RS00700	COG4120	Belongs to the binding-protein-dependent transport system permease family
AN924_RS00720	COG3684	Belongs to the aldolase LacD family
AN924_RS00735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN924_RS00740	COG1126	abc transporter atp-binding protein
AN924_RS00745	COG0765	amino acid transport
AN924_RS00750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AN924_RS00765	COG2755	lipolytic protein G-D-S-L family
AN924_RS00765	COG0657	acetylesterase activity
AN924_RS00770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN924_RS00785	COG0469	pyruvate kinase activity
AN924_RS00790	COG0205	6-phosphofructokinase activity
AN924_RS00800	COG2188	Transcriptional regulator
AN924_RS00805	COG1131	(ABC) transporter
AN924_RS00815	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AN924_RS00845	COG2151	metal-sulfur cluster biosynthetic enzyme
AN924_RS00850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AN924_RS00855	COG0358	DNA primase activity
AN924_RS00860	COG1970	mechanosensitive ion channel activity
AN924_RS00865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AN924_RS00870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AN924_RS00880	COG0647	UMP catabolic process
AN924_RS00885	COG1051	belongs to the nudix hydrolase family
AN924_RS00895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN924_RS00905	COG0058	SHG alpha-glucan phosphorylase activity
AN924_RS00910	COG0813	purine-nucleoside phosphorylase activity
AN924_RS00915	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AN924_RS00925	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AN924_RS00930	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AN924_RS00945	COG1518	maintenance of DNA repeat elements
AN924_RS00955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AN924_RS00970	COG2268	Band 7 protein
AN924_RS00975	COG1704	LemA family
AN924_RS00985	COG1573	uracil-dna glycosylase
AN924_RS01005	COG2226	methyltransferase
AN924_RS01010	COG0488	(ABC) transporter
AN924_RS01015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN924_RS01030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AN924_RS01035	COG3442	glutamine amidotransferase
AN924_RS01040	COG2226	methyltransferase
AN924_RS01050	COG0488	(ABC) transporter
AN924_RS01085	COG3842	ATPase activity
AN924_RS01105	COG2190	(PTS) system
AN924_RS01105	COG1263	PTS System
AN924_RS01105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN924_RS01110	COG3711	transcriptional antiterminator
AN924_RS01115	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AN924_RS01120	COG3527	Alpha-acetolactate decarboxylase
AN924_RS01130	COG0628	permease
AN924_RS01135	COG2706	6-phosphogluconolactonase activity
AN924_RS01145	COG1011	Hydrolase
AN924_RS01265	COG0560	Phosphoserine phosphatase
AN924_RS01270	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AN924_RS01275	COG0187	DNA topoisomerase II activity
AN924_RS01280	COG0693	protein deglycase activity
AN924_RS01285	COG0772	Belongs to the SEDS family
AN924_RS01295	COG4479	Belongs to the UPF0346 family
AN924_RS01310	COG2996	Protein conserved in bacteria
AN924_RS01315	COG0233	cytoplasmic translational termination
AN924_RS01320	COG0528	UMP kinase activity
AN924_RS01325	COG2244	polysaccharide biosynthetic process
AN924_RS01330	COG0625	glutathione transferase activity
AN924_RS01355	COG0346	lactoylglutathione lyase activity
AN924_RS01360	COG1674	ftsk spoiiie
AN924_RS01360	COG0697	spore germination
AN924_RS01365	COG1621	beta-fructofuranosidase activity
AN924_RS01370	COG1653	transport
AN924_RS01375	COG0395	ABC-type sugar transport system, permease component
AN924_RS01380	COG4209	transmembrane transport
AN924_RS01385	COG1609	Transcriptional regulator
AN924_RS01405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AN924_RS01420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AN924_RS01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AN924_RS01450	COG1181	Belongs to the D-alanine--D-alanine ligase family
AN924_RS01455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AN924_RS01460	COG0768	penicillin binding
AN924_RS01465	COG0488	(ABC) transporter
AN924_RS01480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AN924_RS01490	COG0745	RESPONSE REGULATOR receiver
AN924_RS01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN924_RS01505	COG0765	amino acid transport
AN924_RS01510	COG0765	amino acid transport
AN924_RS01515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AN924_RS01530	COG0438	transferase activity, transferring glycosyl groups
AN924_RS01545	COG1609	Transcriptional regulator
AN924_RS01555	COG0343	queuine tRNA-ribosyltransferase activity
AN924_RS01565	COG1832	CoA-binding protein
AN924_RS01575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN924_RS01575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN924_RS01585	COG3547	Transposase (IS116 IS110 IS902 family)
AN924_RS01595	COG1136	(ABC) transporter
AN924_RS01605	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AN924_RS01610	COG2217	Heavy metal translocating P-type atpase
AN924_RS01625	COG1063	alcohol dehydrogenase
AN924_RS01630	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AN924_RS01635	COG0557	exoribonuclease II activity
AN924_RS01645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AN924_RS01650	COG2814	Major facilitator Superfamily
AN924_RS01655	COG0237	dephospho-CoA kinase activity
AN924_RS01660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AN924_RS01665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AN924_RS01670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AN924_RS01680	COG1737	Transcriptional regulator
AN924_RS01710	COG2177	Part of the ABC transporter FtsEX involved in
AN924_RS01715	COG2884	Cell division ATP-binding protein ftsE
AN924_RS01720	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AN924_RS01725	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AN924_RS01760	COG1078	dGTPase activity
AN924_RS01770	COG0149	triose-phosphate isomerase activity
AN924_RS01775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AN924_RS01790	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AN924_RS01795	COG0772	Belongs to the SEDS family
AN924_RS01815	COG3859	Proton-coupled thiamine transporter YuaJ
AN924_RS01825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AN924_RS01835	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AN924_RS01860	COG0577	efflux transmembrane transporter activity
AN924_RS01865	COG1136	(ABC) transporter
AN924_RS01870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN924_RS01885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN924_RS01895	COG1268	BioY protein
AN924_RS01900	COG4443	Transcriptional Coactivator p15 (PC4)
AN924_RS01910	COG0826	peptidase U32
AN924_RS01925	COG0789	Transcriptional regulator
AN924_RS01960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AN924_RS01970	COG0765	amino acid transport
AN924_RS01975	COG4703	Protein of unknown function (DUF1797)
AN924_RS01980	COG0542	response to heat
AN924_RS01985	COG0494	nUDIX hydrolase
AN924_RS01985	COG0406	alpha-ribazole phosphatase activity
AN924_RS02010	COG3599	regulation of cell shape
AN924_RS02025	COG1799	cell septum assembly
AN924_RS02030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AN924_RS02035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AN924_RS02050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AN924_RS02075	COG0681	Belongs to the peptidase S26 family
AN924_RS02090	COG1217	gtp-binding protein TYPA
AN924_RS02105	COG0494	nUDIX hydrolase
AN924_RS02140	COG0346	lactoylglutathione lyase activity
AN924_RS02155	COG2017	converts alpha-aldose to the beta-anomer
AN924_RS02165	COG3716	PTS system mannose fructose sorbose family IID component
AN924_RS02175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN924_RS02185	COG2188	Transcriptional regulator
AN924_RS02190	COG2188	Transcriptional regulator
AN924_RS02200	COG3557	Belongs to the UPF0374 family
AN924_RS02210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN924_RS02290	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AN924_RS02295	COG1739	Uncharacterized protein family UPF0029
AN924_RS02305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN924_RS02310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AN924_RS02330	COG1882	Formate acetyltransferase
AN924_RS02335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN924_RS02340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN924_RS02345	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN924_RS02355	COG1349	DNA-binding transcription factor activity
AN924_RS02360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AN924_RS02400	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AN924_RS02410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AN924_RS02415	COG4684	Psort location CytoplasmicMembrane, score
AN924_RS02420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN924_RS02435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AN924_RS02440	COG1061	Type III restriction enzyme res subunit
AN924_RS02470	COG0531	amino acid
AN924_RS02480	COG0708	Exodeoxyribonuclease III
AN924_RS02490	COG1393	Belongs to the ArsC family
AN924_RS02495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN924_RS02500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN924_RS02510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AN924_RS02520	COG4467	Involved in initiation control of chromosome replication
AN924_RS02525	COG0470	DNA polymerase III
AN924_RS02530	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AN924_RS02535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN924_RS02550	COG0517	IMP dehydrogenase activity
AN924_RS02560	COG0658	competence protein
AN924_RS02560	COG2333	competence protein COMEC
AN924_RS02565	COG1596	polysaccharide export
AN924_RS02565	COG1555	photosystem II stabilization
AN924_RS02570	COG0204	Acyl-transferase
AN924_RS02575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AN924_RS02580	COG1120	ATPase activity
AN924_RS02585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN924_RS02590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN924_RS02595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN924_RS02600	COG0386	Belongs to the glutathione peroxidase family
AN924_RS02605	COG1187	pseudouridine synthase activity
AN924_RS02610	COG0435	Glutathione S-transferase
AN924_RS02620	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AN924_RS02625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN924_RS02630	COG1696	Membrane protein involved in D-alanine export
AN924_RS02660	COG0363	glucosamine-6-phosphate deaminase activity
AN924_RS02665	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AN924_RS02670	COG1438	arginine binding
AN924_RS02675	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AN924_RS02675	COG3583	domain protein
AN924_RS02675	COG3064	Membrane
AN924_RS02680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN924_RS02685	COG1288	antiporter activity
AN924_RS02690	COG0549	Belongs to the carbamate kinase family
AN924_RS02695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AN924_RS02700	COG0454	-acetyltransferase
AN924_RS02715	COG1481	regulation of sporulation
AN924_RS02720	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AN924_RS02725	COG1660	Displays ATPase and GTPase activities
AN924_RS02730	COG0251	oxidation-reduction process
AN924_RS02735	COG0534	Mate efflux family protein
AN924_RS02755	COG0436	Aminotransferase
AN924_RS02770	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AN924_RS02775	COG0562	UDP-galactopyranose mutase
AN924_RS02780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN924_RS02790	COG0077	Prephenate dehydratase
AN924_RS02795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AN924_RS02870	COG2755	lipolytic protein G-D-S-L family
AN924_RS02870	COG1083	cytidylyl-transferase
AN924_RS02885	COG2089	acid synthase
AN924_RS02910	COG1442	glycosyl transferase family 8
AN924_RS02910	COG1216	Glycosyl transferase, family 2
AN924_RS02915	COG1442	glycosyl transferase family 8
AN924_RS02915	COG1216	Glycosyl transferase, family 2
AN924_RS02930	COG0438	transferase activity, transferring glycosyl groups
AN924_RS02945	COG4464	protein tyrosine phosphatase activity
AN924_RS02955	COG3944	biosynthesis protein
AN924_RS02965	COG3022	response to hydroperoxide
AN924_RS02970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN924_RS02985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN924_RS02990	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AN924_RS02995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AN924_RS03155	COG4974	Belongs to the 'phage' integrase family
AN924_RS03165	COG1098	S1 RNA binding domain
AN924_RS03190	COG2815	serine threonine protein kinase
AN924_RS03190	COG0515	serine threonine protein kinase
AN924_RS03195	COG0631	protein serine/threonine phosphatase activity
AN924_RS03200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN924_RS03200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AN924_RS03205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AN924_RS03210	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AN924_RS03215	COG1758	RNA polymerase activity
AN924_RS03225	COG1418	mRNA catabolic process
AN924_RS03230	COG1854	S-ribosylhomocysteine lyase activity
AN924_RS03240	COG0116	Belongs to the methyltransferase superfamily
AN924_RS03250	COG3599	regulation of cell shape
AN924_RS03255	COG4474	Belongs to the UPF0398 family
AN924_RS03260	COG3331	DNA recombination
AN924_RS03265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN924_RS03270	COG0357	Ribosomal RNA small subunit methyltransferase G
AN924_RS03285	COG1122	ATPase activity
AN924_RS03295	COG1054	Belongs to the UPF0176 family
AN924_RS03305	COG4720	Psort location CytoplasmicMembrane, score
AN924_RS03315	COG0217	transcriptional regulatory protein
AN924_RS03330	COG1263	PTS System
AN924_RS03330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN924_RS03330	COG2190	(PTS) system
AN924_RS03345	COG0058	SHG alpha-glucan phosphorylase activity
AN924_RS03350	COG1640	4-alpha-glucanotransferase
AN924_RS03360	COG0242	peptide deformylase activity
AN924_RS03370	COG0789	Transcriptional regulator
AN924_RS03385	COG2226	methyltransferase
AN924_RS03390	COG0799	negative regulation of ribosome biogenesis
AN924_RS03405	COG1713	HD superfamily hydrolase involved in NAD metabolism
AN924_RS03410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AN924_RS03415	COG1534	Rna-binding protein
AN924_RS03420	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AN924_RS03435	COG3142	Participates in the control of copper homeostasis
AN924_RS03450	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AN924_RS03455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AN924_RS03460	COG1609	Transcriptional regulator
AN924_RS03465	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN924_RS03470	COG0154	amidase activity
AN924_RS03475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN924_RS03485	COG0335	large ribosomal subunit rRNA binding
AN924_RS03495	COG1335	isochorismatase
AN924_RS03500	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AN924_RS03505	COG0436	Aminotransferase
AN924_RS03535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AN924_RS03570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AN924_RS03575	COG0191	fructose-bisphosphate aldolase activity
AN924_RS03585	COG0504	CTP synthase activity
AN924_RS03590	COG3343	RNA polymerase activity
AN924_RS03605	COG2801	Transposase and inactivated derivatives
AN924_RS03630	COG0544	peptidyl-prolyl cis-trans isomerase activity
AN924_RS03650	COG1902	pentaerythritol trinitrate reductase activity
AN924_RS03650	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN924_RS03655	COG4221	oxidoreductase activity
AN924_RS03680	COG4475	Protein of unknown function (DUF436)
AN924_RS03705	COG2217	Heavy metal translocating P-type atpase
AN924_RS03715	COG3655	Transcriptional regulator
AN924_RS03730	COG0765	amino acid transport
AN924_RS03735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN924_RS03745	COG0095	Lipoate-protein ligase
AN924_RS03750	COG0484	heat shock protein binding
AN924_RS03755	COG0443	Heat shock 70 kDa protein
AN924_RS03760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AN924_RS03765	COG1420	regulation of RNA biosynthetic process
AN924_RS03770	COG0588	phosphoglycerate mutase activity
AN924_RS03775	COG2848	UPF0210 protein
AN924_RS03780	COG3830	Belongs to the UPF0237 family
AN924_RS03785	COG1132	(ABC) transporter
AN924_RS03790	COG1132	(ABC) transporter
AN924_RS03795	COG1304	FMN binding
AN924_RS03810	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AN924_RS03815	COG0534	Mate efflux family protein
AN924_RS03825	COG1132	(ABC) transporter
AN924_RS03845	COG1454	alcohol dehydrogenase
AN924_RS03845	COG1012	belongs to the aldehyde dehydrogenase family
AN924_RS03850	COG1064	alcohol dehydrogenase
AN924_RS03855	COG0124	histidyl-tRNA synthetase
AN924_RS03860	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AN924_RS03865	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AN924_RS03885	COG0494	nUDIX hydrolase
AN924_RS03890	COG0433	COG0433 Predicted ATPase
AN924_RS03895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AN924_RS03900	COG2116	formate transmembrane transporter activity
AN924_RS03905	COG1346	cytolysis
AN924_RS03930	COG1511	domain protein
AN924_RS03950	COG1309	transcriptional regulator
AN924_RS03955	COG1131	(ABC) transporter
AN924_RS03970	COG0561	phosphatase activity
AN924_RS03975	COG2843	Capsule synthesis protein
AN924_RS03980	COG0167	dihydroorotate dehydrogenase activity
AN924_RS03985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN924_RS04000	COG0668	transmembrane transport
AN924_RS04005	COG1115	amino acid carrier protein
AN924_RS04065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN924_RS04065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN924_RS04075	COG3118	belongs to the thioredoxin family
AN924_RS04140	COG1193	negative regulation of DNA recombination
AN924_RS04155	COG2188	Transcriptional regulator
AN924_RS04160	COG1263	PTS System
AN924_RS04160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN924_RS04165	COG0366	Alpha amylase catalytic
AN924_RS04185	COG0681	Belongs to the peptidase S26 family
AN924_RS04190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AN924_RS04195	COG2217	Heavy metal translocating P-type atpase
AN924_RS04205	COG2217	Heavy metal translocating P-type atpase
AN924_RS04210	COG0363	glucosamine-6-phosphate deaminase activity
AN924_RS04245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN924_RS04270	COG2910	NAD(P)H-binding
AN924_RS04285	COG1882	Formate acetyltransferase
AN924_RS04290	COG3942	CHAP domain
AN924_RS04300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN924_RS04325	COG2222	sugar isomerase
AN924_RS04330	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AN924_RS04335	COG0584	glycerophosphoryl diester phosphodiesterase
AN924_RS04340	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AN924_RS04345	COG3959	Transketolase, thiamine diphosphate binding domain
AN924_RS04360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN924_RS04370	COG2723	6-phospho-beta-galactosidase activity
AN924_RS04375	COG2081	HI0933 family
AN924_RS04385	COG1131	(ABC) transporter
AN924_RS04395	COG2855	membrane
AN924_RS04415	COG0395	ABC-type sugar transport system, permease component
AN924_RS04420	COG1175	transmembrane transport
AN924_RS04430	COG2207	Transcriptional regulator
AN924_RS04435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AN924_RS04445	COG1214	PFAM Peptidase M22, glycoprotease
AN924_RS04460	COG0174	glutamine synthetase
AN924_RS04465	COG0789	Transcriptional regulator
AN924_RS04475	COG0126	phosphoglycerate kinase activity
AN924_RS04485	COG3590	peptidase
AN924_RS04490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AN924_RS04495	COG0049	tRNA binding
AN924_RS04505	COG0459	protein refolding
AN924_RS04530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN924_RS04540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN924_RS04550	COG1363	Peptidase, m42
AN924_RS04555	COG0285	dihydrofolate synthase activity
AN924_RS04565	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AN924_RS04595	COG4537	Required for transformation and DNA binding
AN924_RS04600	COG1459	type II secretion system
AN924_RS04605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN924_RS04610	COG1619	proteins homologs of microcin C7 resistance protein MccF
AN924_RS04620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AN924_RS04625	COG0085	RNA polymerase activity
AN924_RS04630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN924_RS04655	COG0803	Belongs to the bacterial solute-binding protein 9 family
AN924_RS04655	COG3443	Belongs to the bacterial solute-binding protein 9 family
AN924_RS04660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN924_RS04665	COG1121	(ABC) transporter
AN924_RS04705	COG2946	Replication initiation factor
AN924_RS04715	COG0582	viral genome integration into host DNA
AN924_RS04820	COG0202	RNA polymerase activity
AN924_RS04830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AN924_RS04835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AN924_RS04840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AN924_RS04845	COG0563	adenylate kinase activity
AN924_RS04850	COG0201	protein transport
AN924_RS04860	COG1841	ribosomal large subunit assembly
AN924_RS04865	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AN924_RS04870	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AN924_RS04875	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AN924_RS04885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AN924_RS04895	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AN924_RS04900	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AN924_RS04905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AN924_RS04910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AN924_RS04915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AN924_RS04920	COG0255	Belongs to the universal ribosomal protein uL29 family
AN924_RS04925	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AN924_RS04930	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AN924_RS04935	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AN924_RS04940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AN924_RS04945	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AN924_RS04950	COG0089	rRNA binding
AN924_RS04955	COG0088	Forms part of the polypeptide exit tunnel
AN924_RS04960	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AN924_RS04965	COG0051	transcription antitermination factor activity, RNA binding
AN924_RS04980	COG3906	Belongs to the UPF0473 family
AN924_RS04985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AN924_RS04990	COG4472	Bacterial protein of unknown function (DUF965)
AN924_RS04995	COG1393	Belongs to the ArsC family
AN924_RS05010	COG0519	Catalyzes the synthesis of GMP from XMP
AN924_RS05015	COG0632	four-way junction helicase activity
AN924_RS05020	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AN924_RS05035	COG0285	dihydrofolate synthase activity
AN924_RS05045	COG0546	phosphoglycolate phosphatase activity
AN924_RS05055	COG2255	four-way junction helicase activity
AN924_RS05060	COG1132	(ABC) transporter
AN924_RS05070	COG1131	(ABC) transporter
AN924_RS05100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AN924_RS05115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AN924_RS05120	COG0151	Belongs to the GarS family
AN924_RS05145	COG0138	bifunctional purine biosynthesis protein purh
AN924_RS05150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AN924_RS05165	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AN924_RS05175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN924_RS05180	COG0416	fatty acid biosynthetic process
AN924_RS05185	COG1381	Involved in DNA repair and RecF pathway recombination
AN924_RS05190	COG0436	Aminotransferase
AN924_RS05195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AN924_RS05210	COG1792	Involved in formation and maintenance of cell shape
AN924_RS05320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN924_RS05330	COG0037	tRNA processing
AN924_RS05350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AN924_RS05355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AN924_RS05360	COG0193	aminoacyl-tRNA hydrolase activity
AN924_RS05365	COG0012	GTP binding
AN924_RS05385	COG0592	DNA-directed DNA polymerase activity
AN924_RS05390	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AN924_RS05395	COG1475	DNA binding
AN924_RS05400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN924_RS05405	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AN924_RS05435	COG0488	(ABC) transporter
AN924_RS05440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN924_RS05450	COG0517	IMP dehydrogenase activity
AN924_RS05450	COG0516	GMP reductase activity
AN924_RS05460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AN924_RS05470	COG0582	viral genome integration into host DNA
AN924_RS05550	COG0612	Peptidase, M16
AN924_RS05555	COG0612	Peptidase, M16
AN924_RS05560	COG1426	Protein conserved in bacteria
AN924_RS05565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AN924_RS05570	COG1122	ATPase activity
AN924_RS05575	COG1122	ATPase activity
AN924_RS05580	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AN924_RS05590	COG1760	l-serine dehydratase
AN924_RS05595	COG1760	l-serine dehydratase
AN924_RS05600	COG0482	sulfurtransferase activity
AN924_RS05610	COG1733	regulation of RNA biosynthetic process
AN924_RS05615	COG0494	nUDIX hydrolase
AN924_RS05620	COG0445	tRNA wobble uridine modification
AN924_RS05630	COG0359	binds to the 23S rRNA
AN924_RS05635	COG0305	Participates in initiation and elongation during chromosome replication
AN924_RS05645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AN924_RS05665	COG1216	Glycosyl transferase, family 2
AN924_RS05670	COG4989	oxidoreductase activity
AN924_RS05675	COG2153	protein acetylation
AN924_RS05680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AN924_RS05685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN924_RS05690	COG1780	Probably involved in ribonucleotide reductase function
AN924_RS05695	COG1523	belongs to the glycosyl hydrolase 13 family
AN924_RS05700	COG1609	Transcriptional regulator
AN924_RS05705	COG5521	maltodextrose utilization protein MalA
AN924_RS05710	COG3833	ABC-type maltose transport systems, permease component
AN924_RS05715	COG1175	transmembrane transport
AN924_RS05720	COG2182	Extracellular solute-binding protein
AN924_RS05725	COG1640	4-alpha-glucanotransferase
AN924_RS05745	COG0018	arginyl-trna synthetase
AN924_RS05750	COG1438	arginine binding
AN924_RS05765	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AN924_RS05770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN924_RS05780	COG1126	abc transporter atp-binding protein
AN924_RS05785	COG1328	CTP reductase activity
AN924_RS05795	COG0737	Belongs to the 5'-nucleotidase family
AN924_RS05825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AN924_RS05845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AN924_RS05865	COG0737	Belongs to the 5'-nucleotidase family
AN924_RS05875	COG1490	D-aminoacyl-tRNA deacylase activity
AN924_RS05895	COG0803	Belongs to the bacterial solute-binding protein 9 family
AN924_RS05905	COG1121	(ABC) transporter
AN924_RS05910	COG1321	iron dependent repressor
AN924_RS05910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN924_RS05915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN924_RS05920	COG3590	peptidase
AN924_RS05930	COG1486	melibiose metabolic process
AN924_RS05935	COG2723	6-phospho-beta-galactosidase activity
AN924_RS05945	COG3711	transcriptional antiterminator
AN924_RS05945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN924_RS05955	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN924_RS05965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN924_RS05970	COG3942	CHAP domain
AN924_RS05975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN924_RS05980	COG0765	amino acid transport
AN924_RS05985	COG1126	abc transporter atp-binding protein
AN924_RS05990	COG1609	Transcriptional regulator
AN924_RS05995	COG1523	belongs to the glycosyl hydrolase 13 family
AN924_RS06020	COG3623	hexulose-6-phosphate isomerase
AN924_RS06045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AN924_RS06070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AN924_RS06080	COG2171	N-acyltransferase activity
AN924_RS06085	COG1473	amidohydrolase
AN924_RS06090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AN924_RS06095	COG0705	Rhomboid family
AN924_RS06100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN924_RS06105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AN924_RS06115	COG1132	(ABC) transporter
AN924_RS06120	COG1132	(ABC) transporter
AN924_RS06125	COG0756	dUTP diphosphatase activity
AN924_RS06180	COG1827	regulation of RNA biosynthetic process
AN924_RS06190	COG0137	argininosuccinate synthase activity
AN924_RS06195	COG0165	Argininosuccinate lyase
AN924_RS06200	COG0594	ribonuclease P activity
AN924_RS06210	COG1847	R3H domain protein
AN924_RS06220	COG0084	hydrolase, TatD family'
AN924_RS06255	COG4115	mRNA cleavage
AN924_RS06310	COG1162	GTPase activity
AN924_RS06320	COG1564	THIamine pyrophosphokinase
AN924_RS06340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN924_RS06345	COG0564	pseudouridine synthase activity
AN924_RS06350	COG0492	ferredoxin-NADP+ reductase activity
AN924_RS06355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN924_RS06360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AN924_RS06395	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AN924_RS06405	COG1388	LysM domain
AN924_RS06405	COG4932	domain protein
AN924_RS06415	COG4463	regulation of RNA biosynthetic process
AN924_RS06420	COG0542	response to heat
AN924_RS06425	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AN924_RS06430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN924_RS06435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AN924_RS06445	COG1181	Belongs to the D-alanine--D-alanine ligase family
AN924_RS06445	COG2918	glutathione biosynthetic process
AN924_RS06455	COG1862	Preprotein translocase
AN924_RS06460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AN924_RS06465	COG4589	Belongs to the CDS family
AN924_RS06475	COG0442	prolyl-tRNA aminoacylation
AN924_RS06480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AN924_RS06485	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AN924_RS06490	COG1461	Dihydroxyacetone kinase
AN924_RS06495	COG2376	Dihydroxyacetone kinase
AN924_RS06505	COG2376	Dihydroxyacetone kinase
AN924_RS06510	COG2176	DNA-directed DNA polymerase activity
AN924_RS06530	COG2309	aminopeptidase activity
AN924_RS06545	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN924_RS06550	COG2188	Transcriptional regulator
AN924_RS06560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN924_RS06580	COG0066	3-isopropylmalate dehydratase activity
AN924_RS06590	COG0242	peptide deformylase activity
AN924_RS06605	COG1187	pseudouridine synthase activity
AN924_RS06615	COG2801	Transposase and inactivated derivatives
AN924_RS06655	COG1131	(ABC) transporter
AN924_RS06660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AN924_RS06665	COG1185	polyribonucleotide nucleotidyltransferase activity
AN924_RS06670	COG1045	serine acetyltransferase
AN924_RS06690	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AN924_RS06700	COG3842	ATPase activity
AN924_RS06715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN924_RS06730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AN924_RS06780	COG2151	metal-sulfur cluster biosynthetic enzyme
AN924_RS06790	COG0129	dihydroxy-acid dehydratase activity
AN924_RS06805	COG0463	Glycosyl transferase, family 2
AN924_RS06810	COG0028	Belongs to the TPP enzyme family
AN924_RS06815	COG0440	acetolactate synthase activity
AN924_RS06820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AN924_RS06825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AN924_RS06840	COG1126	abc transporter atp-binding protein
AN924_RS06845	COG0765	amino acid transport
AN924_RS06850	COG1968	undecaprenyl-diphosphatase activity
AN924_RS06855	COG4862	establishment of competence for transformation
AN924_RS06860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN924_RS06870	COG0719	Fe-S assembly protein
AN924_RS06875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN924_RS06890	COG1686	Belongs to the peptidase S11 family
AN924_RS06895	COG0747	negative chemotaxis
AN924_RS06905	COG4608	Belongs to the ABC transporter superfamily
AN924_RS06910	COG0601	transmembrane transport
AN924_RS06915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN924_RS06935	COG0802	atpase or kinase
AN924_RS06945	COG1316	TRANSCRIPTIONal
AN924_RS06955	COG0537	adenosine 5'-monophosphoramidase activity
AN924_RS06960	COG1131	(ABC) transporter
AN924_RS06965	COG4473	ABC transporter
AN924_RS06975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AN924_RS06985	COG0195	Participates in both transcription termination and antitermination
AN924_RS06990	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AN924_RS07000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AN924_RS07005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AN924_RS07020	COG2860	membrane
AN924_RS07025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AN924_RS07030	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN924_RS07030	COG0022	dehydrogenase e1 component
AN924_RS07035	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN924_RS07050	COG3711	transcriptional antiterminator
AN924_RS07055	COG1263	PTS System
AN924_RS07055	COG2190	(PTS) system
AN924_RS07055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN924_RS07065	COG2207	Transcriptional regulator
AN924_RS07065	COG1917	Cupin 2, conserved barrel domain protein
AN924_RS07070	COG2723	6-phospho-beta-galactosidase activity
AN924_RS07075	COG0346	lactoylglutathione lyase activity
AN924_RS07080	COG2723	6-phospho-beta-galactosidase activity
AN924_RS07085	COG4095	Psort location CytoplasmicMembrane, score
AN924_RS07100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN924_RS07100	COG3711	transcriptional antiterminator
AN924_RS07105	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN924_RS07115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN924_RS07120	COG2723	6-phospho-beta-galactosidase activity
AN924_RS07135	COG2723	6-phospho-beta-galactosidase activity
AN924_RS07140	COG0095	Lipoate-protein ligase
AN924_RS07150	COG0629	single-stranded DNA binding
AN924_RS07155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AN924_RS07170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AN924_RS07175	COG0006	proline dipeptidase activity
AN924_RS07190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN924_RS07195	COG1609	Transcriptional regulator
AN924_RS07200	COG1621	beta-fructofuranosidase activity
AN924_RS07205	COG1263	PTS System
AN924_RS07205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN924_RS07205	COG2190	(PTS) system
AN924_RS07210	COG1940	carbohydrate kinase activity
AN924_RS07220	COG0653	protein targeting
AN924_RS07225	COG0736	holo-[acyl-carrier-protein] synthase activity
AN924_RS07230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN924_RS07240	COG0527	aspartate kinase activity
AN924_RS07245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN924_RS07250	COG1024	Enoyl-CoA hydratase
AN924_RS07260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN924_RS07270	COG2070	2-Nitropropane dioxygenase
AN924_RS07275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AN924_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
AN924_RS07300	COG0439	Biotin carboxylase
AN924_RS07310	COG0825	malonyl-CoA metabolic process
AN924_RS07345	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AN924_RS07355	COG3177	Filamentation induced by cAMP protein fic
AN924_RS07370	COG3177	Filamentation induced by cAMP protein fic
AN924_RS07400	COG3716	PTS system mannose fructose sorbose family IID component
AN924_RS07405	COG3715	PTS system
AN924_RS07415	COG0561	phosphatase activity
AN924_RS07425	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AN924_RS07430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AN924_RS07435	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AN924_RS07440	COG1464	Belongs to the NlpA lipoprotein family
AN924_RS07445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN924_RS07450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AN924_RS07475	COG0751	glycine-tRNA ligase activity
AN924_RS07480	COG4224	UPF0291 protein
AN924_RS07490	COG0534	Mate efflux family protein
AN924_RS07495	COG0569	domain protein
AN924_RS07500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN924_RS07510	COG1252	NADH dehydrogenase
AN924_RS07515	COG0142	geranyltranstransferase activity
AN924_RS07520	COG4939	FMN-binding domain protein
AN924_RS07580	COG0275	rRNA processing
AN924_RS07590	COG0768	penicillin binding
AN924_RS07595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN924_RS07615	COG0513	Belongs to the DEAD box helicase family
AN924_RS07625	COG0492	ferredoxin-NADP+ reductase activity
AN924_RS07635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AN924_RS07640	COG0745	RESPONSE REGULATOR receiver
AN924_RS07645	COG0628	permease
AN924_RS07650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AN924_RS07660	COG1484	DNA-dependent DNA replication
AN924_RS07670	COG1160	GTP binding
AN924_RS07685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AN924_RS07695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AN924_RS07705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AN924_RS07710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN924_RS07720	COG1254	Belongs to the acylphosphatase family
AN924_RS07725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN924_RS07740	COG3579	cysteine-type endopeptidase activity
AN924_RS07750	COG3763	UPF0154 protein
AN924_RS07755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AN924_RS07775	COG0582	viral genome integration into host DNA
AN924_RS07780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AN924_RS07785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AN924_RS07790	COG1187	pseudouridine synthase activity
AN924_RS07795	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AN924_RS07810	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AN924_RS07815	COG0671	phosphoesterase, PA-phosphatase related
AN924_RS07820	COG2755	lipolytic protein G-D-S-L family
AN924_RS07820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AN924_RS07830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN924_RS07845	COG1131	(ABC) transporter
AN924_RS07850	COG0842	Transport permease protein
AN924_RS07855	COG2203	Gaf domain
AN924_RS07855	COG4585	Histidine kinase
AN924_RS07860	COG2197	response regulator
AN924_RS07865	COG4483	Protein conserved in bacteria
AN924_RS07870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN924_RS07880	COG0742	ribosomal rna small subunit methyltransferase
AN924_RS07885	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AN924_RS07890	COG3480	Lon protease (S16) C-terminal proteolytic domain
AN924_RS07895	COG4470	Protein conserved in bacteria
AN924_RS07910	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AN924_RS07915	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AN924_RS07925	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AN924_RS07930	COG1119	ATPase activity
AN924_RS07935	COG1253	flavin adenine dinucleotide binding
AN924_RS07940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AN924_RS07950	COG1227	inorganic diphosphatase activity
AN924_RS07970	COG0745	RESPONSE REGULATOR receiver
AN924_RS07975	COG5002	protein histidine kinase activity
AN924_RS07980	COG1755	Isoprenylcysteine carboxyl methyltransferase
AN924_RS07985	COG2321	neutral zinc metallopeptidase
AN924_RS07990	COG1570	exodeoxyribonuclease VII activity
AN924_RS07995	COG1722	exodeoxyribonuclease VII activity
AN924_RS08005	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AN924_RS08010	COG1438	arginine binding
AN924_RS08015	COG0497	DNA recombination
AN924_RS08020	COG1307	EDD domain protein, DegV family
AN924_RS08025	COG2755	lipolytic protein G-D-S-L family
AN924_RS08035	COG0776	regulation of translation
AN924_RS08060	COG3425	synthase
AN924_RS08065	COG0183	Belongs to the thiolase family
AN924_RS08080	COG0726	polysaccharide deacetylase
AN924_RS08085	COG0513	Belongs to the DEAD box helicase family
AN924_RS08090	COG0673	inositol 2-dehydrogenase activity
AN924_RS08100	COG1695	Transcriptional regulator
AN924_RS08110	COG1956	GAF domain-containing protein
AN924_RS08115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AN924_RS08130	COG1363	Peptidase, m42
AN924_RS08150	COG2131	deaminase
AN924_RS08160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AN924_RS08165	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN924_RS08170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN924_RS08180	COG0024	Methionine aminopeptidase
AN924_RS08190	COG2246	polysaccharide biosynthetic process
AN924_RS08195	COG4708	membrane
AN924_RS08200	COG0656	L-ascorbic acid biosynthetic process
AN924_RS08220	COG2183	response to ionizing radiation
AN924_RS08225	COG3091	SprT-like family
AN924_RS08240	COG1482	cell wall glycoprotein biosynthetic process
AN924_RS08245	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AN924_RS08250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AN924_RS08270	COG0517	IMP dehydrogenase activity
AN924_RS08270	COG1125	glycine betaine transport
AN924_RS08275	COG1174	glycine betaine transport
AN924_RS08285	COG0436	Aminotransferase
AN924_RS08300	COG2205	protein histidine kinase activity
AN924_RS08305	COG1136	(ABC) transporter
AN924_RS08310	COG0577	efflux transmembrane transporter activity
AN924_RS08335	COG1028	Short-chain dehydrogenase reductase Sdr
AN924_RS08340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN924_RS08350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AN924_RS08355	COG0494	nUDIX hydrolase
AN924_RS08400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN924_RS08405	COG0513	Belongs to the DEAD box helicase family
AN924_RS08410	COG0640	Transcriptional regulator
AN924_RS08430	COG2827	Endonuclease containing a URI domain
AN924_RS08435	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AN924_RS08440	COG3547	Transposase (IS116 IS110 IS902 family)
AN924_RS08460	COG0626	cystathionine gamma-synthase activity
AN924_RS08465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AN924_RS08470	COG2207	Transcriptional regulator
AN924_RS08480	COG1653	transport
AN924_RS08485	COG1175	transmembrane transport
AN924_RS08490	COG0395	ABC-type sugar transport system, permease component
AN924_RS08500	COG0366	Alpha amylase catalytic
AN924_RS08505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AN924_RS08520	COG0683	leucine binding
AN924_RS08555	COG1466	dna polymerase III delta subunit
AN924_RS08560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AN924_RS08565	COG0737	Belongs to the 5'-nucleotidase family
AN924_RS08575	COG0038	chloride channel
AN924_RS08580	COG0287	Prephenate dehydrogenase
AN924_RS08580	COG1605	Chorismate mutase
AN924_RS08590	COG0716	FMN binding
AN924_RS08595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AN924_RS08615	COG1702	phosphate starvation-inducible protein PhoH
AN924_RS08620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AN924_RS08625	COG2807	transmembrane transport
AN924_RS08635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AN924_RS08640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AN924_RS08650	COG1234	tRNA 3'-trailer cleavage
AN924_RS08655	COG0300	oxidoreductase activity
AN924_RS08665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN924_RS08670	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AN924_RS08670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AN924_RS08680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN924_RS08695	COG2384	SAM-dependent methyltransferase
AN924_RS08700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AN924_RS08710	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AN924_RS08725	COG1088	dTDP-glucose 4,6-dehydratase activity
AN924_RS08730	COG1091	dTDP-4-dehydrorhamnose reductase activity
AN924_RS08760	COG1216	Glycosyl transferase, family 2
AN924_RS08760	COG1442	glycosyl transferase family 8
AN924_RS08790	COG1442	glycosyl transferase family 8
AN924_RS08795	COG1216	Glycosyl transferase, family 2
AN924_RS08795	COG1442	glycosyl transferase family 8
AN924_RS08810	COG1216	Glycosyl transferase, family 2
AN924_RS08840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AN924_RS08850	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AN924_RS08865	COG1368	sulfuric ester hydrolase activity
AN924_RS08870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AN924_RS08875	COG0710	3-dehydroquinate dehydratase activity
AN924_RS08880	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AN924_RS08885	COG0287	Prephenate dehydrogenase
AN924_RS08890	COG3679	Belongs to the UPF0342 family
AN924_RS09015	COG1164	Oligoendopeptidase f
AN924_RS09030	COG0210	DNA helicase
AN924_RS09040	COG1011	Hydrolase
AN924_RS09070	COG1131	(ABC) transporter
AN924_RS09100	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AN924_RS09105	COG1074	ATP-dependent DNA helicase activity
AN924_RS09115	COG0187	DNA topoisomerase II activity
AN924_RS09120	COG2184	nucleotidyltransferase activity
AN924_RS09135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AN924_RS09145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN924_RS09170	COG0539	negative regulation of cytoplasmic translation
AN924_RS09195	COG1104	cysteine desulfurase activity
AN924_RS09200	COG0301	tRNA thio-modification
AN924_RS09205	COG1114	Component of the transport system for branched-chain amino acids
AN924_RS09210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AN924_RS09215	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AN924_RS09235	COG0564	pseudouridine synthase activity
AN924_RS09240	COG2824	Alkylphosphonate utilization operon protein PhnA
AN924_RS09250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AN924_RS09255	COG0540	Belongs to the ATCase OTCase family
AN924_RS09260	COG0505	Belongs to the CarA family
AN924_RS09270	COG2136	Putative SAM-dependent methyltransferase
AN924_RS09270	COG2521	methyltransferase
AN924_RS09275	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AN924_RS09285	COG0228	four-way junction DNA binding
AN924_RS09300	COG1132	(ABC) transporter
AN924_RS09305	COG0726	polysaccharide deacetylase
AN924_RS09315	COG0083	homoserine kinase activity
AN924_RS09325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AN924_RS09330	COG3842	ATPase activity
AN924_RS09335	COG1176	ABC-type spermidine putrescine transport system, permease component I
AN924_RS09340	COG1177	transmembrane transport
AN924_RS09350	COG0038	chloride channel
AN924_RS09360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AN924_RS09365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AN924_RS09375	COG0534	Mate efflux family protein
AN924_RS09380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AN924_RS09385	COG0336	Belongs to the RNA methyltransferase TrmD family
AN924_RS09390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AN924_RS09395	COG1349	DNA-binding transcription factor activity
AN924_RS09400	COG1105	Belongs to the carbohydrate kinase PfkB family
AN924_RS09405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN924_RS09405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN924_RS09405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN924_RS09415	COG1307	EDD domain protein, DegV family
AN924_RS09420	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AN924_RS09425	COG0617	tRNA 3'-terminal CCA addition
AN924_RS09430	COG0488	(ABC) transporter
AN924_RS09440	COG1940	carbohydrate kinase activity
AN924_RS09455	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AN924_RS09460	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AN924_RS09470	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AN924_RS09485	COG0481	GTPase activity
AN924_RS09510	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AN924_RS09515	COG2890	protein-(glutamine-N5) methyltransferase activity
AN924_RS09520	COG0009	L-threonylcarbamoyladenylate synthase
AN924_RS09530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AN924_RS09540	COG0741	lytic transglycosylase activity
AN924_RS09545	COG4221	oxidoreductase activity
AN924_RS09570	COG1401	restriction endodeoxyribonuclease activity
AN924_RS09575	COG4268	DNA restriction-modification system
AN924_RS09585	COG2188	Transcriptional regulator
AN924_RS09590	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AN924_RS09595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AN924_RS09610	COG1660	Displays ATPase and GTPase activities
AN924_RS09615	COG4974	Belongs to the 'phage' integrase family
AN924_RS09625	COG5002	protein histidine kinase activity
AN924_RS09630	COG0745	RESPONSE REGULATOR receiver
AN924_RS09650	COG1136	(ABC) transporter
AN924_RS09680	COG2382	esterase
AN924_RS09690	COG2207	Transcriptional regulator
AN924_RS09690	COG3708	Transcriptional regulator
AN924_RS09695	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AN924_RS09700	COG0647	UMP catabolic process
AN924_RS09740	COG0395	ABC-type sugar transport system, permease component
AN924_RS09745	COG1175	transmembrane transport
AN924_RS09765	COG1070	Carbohydrate kinase
AN924_RS09780	COG3843	relaxase mobilization nuclease domain protein
AN924_RS09795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN924_RS09815	COG0827	DNA restriction-modification system
AN924_RS09830	COG0270	DNA (cytosine-5-)-methyltransferase activity
AN924_RS09855	COG1705	Flagellar rod assembly protein muramidase FlgJ
AN924_RS09855	COG3942	CHAP domain
AN924_RS09905	COG4974	Belongs to the 'phage' integrase family
AN924_RS09950	COG1131	(ABC) transporter
AN924_RS09970	COG3843	relaxase mobilization nuclease domain protein
AN924_RS10000	COG0542	response to heat
AN924_RS10005	COG1396	sequence-specific DNA binding
AN924_RS10075	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AN924_RS10100	COG1192	Involved in chromosome partitioning
AN924_RS10125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AN924_RS10230	COG0270	DNA (cytosine-5-)-methyltransferase activity
AN924_RS10245	COG0222	ribosome binding
AN924_RS10250	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AN924_RS10255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AN924_RS10260	COG0758	DNA mediated transformation
AN924_RS10265	COG0110	maltose O-acetyltransferase activity
AN924_RS10270	COG1937	Protein conserved in bacteria
AN924_RS10280	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN924_RS10290	COG1272	protein, Hemolysin III
AN924_RS10300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AN924_RS10305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AN924_RS10320	COG0737	Belongs to the 5'-nucleotidase family
AN924_RS10330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AN924_RS10335	COG0463	Glycosyl transferase, family 2
AN924_RS10345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AN924_RS10350	COG0284	orotidine-5'-phosphate decarboxylase activity
AN924_RS10355	COG0167	dihydroorotate dehydrogenase activity
AN924_RS10365	COG0583	DNA-binding transcription factor activity
AN924_RS10380	COG0297	glycogen (starch) synthase activity
AN924_RS10390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN924_RS10395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN924_RS10440	COG1126	abc transporter atp-binding protein
AN924_RS10450	COG0488	(ABC) transporter
AN924_RS10455	COG2873	o-acetylhomoserine
AN924_RS10480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN924_RS10480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN924_RS10490	COG3711	transcriptional antiterminator
AN924_RS10495	COG3684	Belongs to the aldolase LacD family
AN924_RS10500	COG1105	Belongs to the carbohydrate kinase PfkB family
AN924_RS10505	COG0698	ribose 5-phosphate isomerase
AN924_RS10510	COG0698	ribose 5-phosphate isomerase
AN924_RS10520	COG1349	DNA-binding transcription factor activity
AN924_RS10550	COG1396	sequence-specific DNA binding
AN924_RS10555	COG1194	a g-specific adenine glycosylase
AN924_RS10565	COG1132	(ABC) transporter
AN924_RS10570	COG1132	(ABC) transporter
AN924_RS10575	COG0280	phosphate acetyltransferase
AN924_RS10580	COG0564	pseudouridine synthase activity
AN924_RS10585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN924_RS10590	COG2357	RelA SpoT domain protein
AN924_RS10595	COG4116	CYTH
AN924_RS10605	COG1104	cysteine desulfurase activity
AN924_RS10620	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AN924_RS10625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AN924_RS10635	COG3764	Sortase (surface protein transpeptidase)
AN924_RS10640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AN924_RS10645	COG0039	L-malate dehydrogenase activity
AN924_RS10650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AN924_RS10660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AN924_RS10665	COG1079	Belongs to the binding-protein-dependent transport system permease family
AN924_RS10670	COG4603	Belongs to the binding-protein-dependent transport system permease family
AN924_RS10675	COG3845	ABC transporter
AN924_RS10680	COG1744	ABC transporter substrate-binding protein PnrA-like
AN924_RS10695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AN924_RS10700	COG2813	Specifically methylates the guanine in position