locus-tag	class	description
CWI26_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CWI26_RS00010	COG0592	DNA-directed DNA polymerase activity
CWI26_RS00035	COG0012	GTP binding
CWI26_RS00040	COG0193	aminoacyl-tRNA hydrolase activity
CWI26_RS00045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CWI26_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CWI26_RS00070	COG0037	tRNA processing
CWI26_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CWI26_RS00195	COG1792	Involved in formation and maintenance of cell shape
CWI26_RS00210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CWI26_RS00215	COG0436	Aminotransferase
CWI26_RS00220	COG1381	Involved in DNA repair and RecF pathway recombination
CWI26_RS00225	COG0416	fatty acid biosynthetic process
CWI26_RS00230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWI26_RS00240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWI26_RS00255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CWI26_RS00265	COG0138	bifunctional purine biosynthesis protein purh
CWI26_RS00280	COG3583	domain protein
CWI26_RS00295	COG0151	Belongs to the GarS family
CWI26_RS00300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CWI26_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CWI26_RS00340	COG1131	(ABC) transporter
CWI26_RS00350	COG1132	(ABC) transporter
CWI26_RS00355	COG0789	Transcriptional regulator
CWI26_RS00370	COG2255	four-way junction helicase activity
CWI26_RS00375	COG0546	phosphoglycolate phosphatase activity
CWI26_RS00385	COG0285	dihydrofolate synthase activity
CWI26_RS00400	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CWI26_RS00410	COG1266	CAAX protease self-immunity
CWI26_RS00415	COG0632	four-way junction helicase activity
CWI26_RS00420	COG0519	Catalyzes the synthesis of GMP from XMP
CWI26_RS00435	COG1393	Belongs to the ArsC family
CWI26_RS00440	COG4472	Bacterial protein of unknown function (DUF965)
CWI26_RS00445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CWI26_RS00450	COG3906	Belongs to the UPF0473 family
CWI26_RS00475	COG0051	transcription antitermination factor activity, RNA binding
CWI26_RS00480	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CWI26_RS00485	COG0088	Forms part of the polypeptide exit tunnel
CWI26_RS00490	COG0089	rRNA binding
CWI26_RS00495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CWI26_RS00500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CWI26_RS00505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CWI26_RS00510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CWI26_RS00515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CWI26_RS00520	COG0255	Belongs to the universal ribosomal protein uL29 family
CWI26_RS00525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CWI26_RS00530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CWI26_RS00535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CWI26_RS00540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CWI26_RS00545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CWI26_RS00550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CWI26_RS00555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CWI26_RS00560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CWI26_RS00565	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CWI26_RS00570	COG1841	ribosomal large subunit assembly
CWI26_RS00580	COG0201	protein transport
CWI26_RS00585	COG0563	adenylate kinase activity
CWI26_RS00590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWI26_RS00595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CWI26_RS00600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CWI26_RS00610	COG0202	RNA polymerase activity
CWI26_RS00720	COG1121	(ABC) transporter
CWI26_RS00725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWI26_RS00730	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWI26_RS00730	COG3443	Belongs to the bacterial solute-binding protein 9 family
CWI26_RS00775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWI26_RS00785	COG0085	RNA polymerase activity
CWI26_RS00790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CWI26_RS00805	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWI26_RS00810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CWI26_RS00815	COG1459	type II secretion system
CWI26_RS00820	COG4537	Required for transformation and DNA binding
CWI26_RS00850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CWI26_RS00865	COG0285	dihydrofolate synthase activity
CWI26_RS00880	COG1363	Peptidase, m42
CWI26_RS00890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWI26_RS00900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWI26_RS00925	COG0459	protein refolding
CWI26_RS00935	COG0049	tRNA binding
CWI26_RS00940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CWI26_RS00950	COG0126	phosphoglycerate kinase activity
CWI26_RS00960	COG0789	Transcriptional regulator
CWI26_RS00965	COG0174	glutamine synthetase
CWI26_RS00980	COG1396	sequence-specific DNA binding
CWI26_RS01000	COG1214	PFAM Peptidase M22, glycoprotease
CWI26_RS01010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CWI26_RS01060	COG1131	(ABC) transporter
CWI26_RS01070	COG2081	HI0933 family
CWI26_RS01095	COG0584	glycerophosphoryl diester phosphodiesterase
CWI26_RS01100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CWI26_RS01105	COG2222	sugar isomerase
CWI26_RS01125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWI26_RS01130	COG1882	Formate acetyltransferase
CWI26_RS01135	COG0366	Alpha amylase catalytic
CWI26_RS01135	COG0366	Alpha amylase catalytic
CWI26_RS01155	COG2910	NAD(P)H-binding
CWI26_RS01185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWI26_RS01195	COG0681	Belongs to the peptidase S26 family
CWI26_RS01235	COG0366	Alpha amylase catalytic
CWI26_RS01240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI26_RS01240	COG1263	PTS System
CWI26_RS01245	COG2188	Transcriptional regulator
CWI26_RS01270	COG1193	negative regulation of DNA recombination
CWI26_RS01295	COG3279	Response regulator of the LytR AlgR family
CWI26_RS01310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI26_RS01315	COG2274	protein secretion by the type I secretion system
CWI26_RS01340	COG3118	belongs to the thioredoxin family
CWI26_RS01355	COG3118	belongs to the thioredoxin family
CWI26_RS01360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWI26_RS01360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWI26_RS01375	COG1115	amino acid carrier protein
CWI26_RS01380	COG0668	transmembrane transport
CWI26_RS01395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWI26_RS01400	COG0167	dihydroorotate dehydrogenase activity
CWI26_RS01405	COG2843	Capsule synthesis protein
CWI26_RS01410	COG0561	phosphatase activity
CWI26_RS01425	COG1131	(ABC) transporter
CWI26_RS01430	COG1309	transcriptional regulator
CWI26_RS01435	COG1511	domain protein
CWI26_RS01440	COG4152	abc transporter atp-binding protein
CWI26_RS01445	COG1668	transmembrane transport
CWI26_RS01470	COG1346	cytolysis
CWI26_RS01475	COG2116	formate transmembrane transporter activity
CWI26_RS01480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWI26_RS01490	COG0494	nUDIX hydrolase
CWI26_RS01495	COG1349	DNA-binding transcription factor activity
CWI26_RS01505	COG0698	ribose 5-phosphate isomerase
CWI26_RS01510	COG0698	ribose 5-phosphate isomerase
CWI26_RS01515	COG1105	Belongs to the carbohydrate kinase PfkB family
CWI26_RS01520	COG3684	Belongs to the aldolase LacD family
CWI26_RS01525	COG3711	transcriptional antiterminator
CWI26_RS01535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI26_RS01535	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI26_RS01550	COG1408	metallophosphoesterase
CWI26_RS01570	COG0582	viral genome integration into host DNA
CWI26_RS01590	COG1674	ftsk spoiiie
CWI26_RS01620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWI26_RS01625	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CWI26_RS01640	COG0124	histidyl-tRNA synthetase
CWI26_RS01645	COG1064	alcohol dehydrogenase
CWI26_RS01650	COG1012	belongs to the aldehyde dehydrogenase family
CWI26_RS01650	COG1454	alcohol dehydrogenase
CWI26_RS01660	COG4988	ABC transporter
CWI26_RS01680	COG1129	ABC transporter
CWI26_RS01685	COG0534	Mate efflux family protein
CWI26_RS01705	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWI26_RS01720	COG1304	FMN binding
CWI26_RS01725	COG1132	(ABC) transporter
CWI26_RS01730	COG1132	(ABC) transporter
CWI26_RS01735	COG3830	Belongs to the UPF0237 family
CWI26_RS01740	COG2848	UPF0210 protein
CWI26_RS01750	COG0588	phosphoglycerate mutase activity
CWI26_RS01765	COG1420	regulation of RNA biosynthetic process
CWI26_RS01775	COG0443	Heat shock 70 kDa protein
CWI26_RS01780	COG0484	heat shock protein binding
CWI26_RS01790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI26_RS01795	COG0765	amino acid transport
CWI26_RS01810	COG3655	Transcriptional regulator
CWI26_RS01820	COG2217	Heavy metal translocating P-type atpase
CWI26_RS01835	COG0351	phosphomethylpyrimidine kinase
CWI26_RS01845	COG4475	Protein of unknown function (DUF436)
CWI26_RS01860	COG1063	alcohol dehydrogenase
CWI26_RS01875	COG2910	NAD(P)H-binding
CWI26_RS01880	COG1959	2 iron, 2 sulfur cluster binding
CWI26_RS01900	COG0544	peptidyl-prolyl cis-trans isomerase activity
CWI26_RS01915	COG3343	RNA polymerase activity
CWI26_RS01920	COG0504	CTP synthase activity
CWI26_RS01930	COG0191	fructose-bisphosphate aldolase activity
CWI26_RS01935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CWI26_RS01985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CWI26_RS02015	COG0436	Aminotransferase
CWI26_RS02020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CWI26_RS02025	COG1335	isochorismatase
CWI26_RS02030	COG0335	large ribosomal subunit rRNA binding
CWI26_RS02040	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWI26_RS02045	COG0154	amidase activity
CWI26_RS02050	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWI26_RS02075	COG1609	Transcriptional regulator
CWI26_RS02080	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWI26_RS02085	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CWI26_RS02095	COG3142	Participates in the control of copper homeostasis
CWI26_RS02110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWI26_RS02120	COG1534	Rna-binding protein
CWI26_RS02125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CWI26_RS02130	COG1713	HD superfamily hydrolase involved in NAD metabolism
CWI26_RS02140	COG1335	isochorismatase
CWI26_RS02145	COG0799	negative regulation of ribosome biogenesis
CWI26_RS02155	COG2226	methyltransferase
CWI26_RS02175	COG0789	Transcriptional regulator
CWI26_RS02180	COG2348	transferase activity, transferring amino-acyl groups
CWI26_RS02190	COG0242	peptide deformylase activity
CWI26_RS02200	COG1640	4-alpha-glucanotransferase
CWI26_RS02205	COG0058	SHG alpha-glucan phosphorylase activity
CWI26_RS02220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI26_RS02220	COG1263	PTS System
CWI26_RS02220	COG2190	(PTS) system
CWI26_RS02225	COG0217	transcriptional regulatory protein
CWI26_RS02235	COG4720	Psort location CytoplasmicMembrane, score
CWI26_RS02250	COG1054	Belongs to the UPF0176 family
CWI26_RS02260	COG1122	ATPase activity
CWI26_RS02275	COG0357	Ribosomal RNA small subunit methyltransferase G
CWI26_RS02280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWI26_RS02285	COG3331	DNA recombination
CWI26_RS02290	COG4474	Belongs to the UPF0398 family
CWI26_RS02295	COG3599	regulation of cell shape
CWI26_RS02305	COG0116	Belongs to the methyltransferase superfamily
CWI26_RS02315	COG1854	S-ribosylhomocysteine lyase activity
CWI26_RS02320	COG1418	mRNA catabolic process
CWI26_RS02455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWI26_RS02540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CWI26_RS02610	COG1758	RNA polymerase activity
CWI26_RS02615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWI26_RS02620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CWI26_RS02625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWI26_RS02625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWI26_RS02630	COG0631	protein serine/threonine phosphatase activity
CWI26_RS02635	COG0515	serine threonine protein kinase
CWI26_RS02635	COG2815	serine threonine protein kinase
CWI26_RS02665	COG1098	S1 RNA binding domain
CWI26_RS02675	COG1739	Uncharacterized protein family UPF0029
CWI26_RS02680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CWI26_RS02780	COG4372	Transposase
CWI26_RS02795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWI26_RS02800	COG2137	regulation of response to DNA damage stimulus
CWI26_RS02805	COG3557	Belongs to the UPF0374 family
CWI26_RS02815	COG2188	Transcriptional regulator
CWI26_RS02820	COG2188	Transcriptional regulator
CWI26_RS02830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI26_RS02840	COG3716	PTS system mannose fructose sorbose family IID component
CWI26_RS02850	COG2017	converts alpha-aldose to the beta-anomer
CWI26_RS02865	COG0346	lactoylglutathione lyase activity
CWI26_RS02920	COG1217	gtp-binding protein TYPA
CWI26_RS02940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CWI26_RS02955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CWI26_RS02960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CWI26_RS02965	COG1799	cell septum assembly
CWI26_RS02980	COG3599	regulation of cell shape
CWI26_RS03000	COG0406	alpha-ribazole phosphatase activity
CWI26_RS03000	COG0494	nUDIX hydrolase
CWI26_RS03005	COG0542	response to heat
CWI26_RS03010	COG4703	Protein of unknown function (DUF1797)
CWI26_RS03015	COG0765	amino acid transport
CWI26_RS03025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CWI26_RS03050	COG0745	RESPONSE REGULATOR receiver
CWI26_RS03055	COG5002	protein histidine kinase activity
CWI26_RS03060	COG1755	Isoprenylcysteine carboxyl methyltransferase
CWI26_RS03065	COG2321	neutral zinc metallopeptidase
CWI26_RS03070	COG1570	exodeoxyribonuclease VII activity
CWI26_RS03075	COG1722	exodeoxyribonuclease VII activity
CWI26_RS03085	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CWI26_RS03090	COG1438	arginine binding
CWI26_RS03095	COG0497	DNA recombination
CWI26_RS03100	COG1307	EDD domain protein, DegV family
CWI26_RS03105	COG2755	lipolytic protein G-D-S-L family
CWI26_RS03115	COG0776	regulation of translation
CWI26_RS03135	COG4372	Transposase
CWI26_RS03150	COG3425	synthase
CWI26_RS03155	COG0183	Belongs to the thiolase family
CWI26_RS03170	COG0726	polysaccharide deacetylase
CWI26_RS03175	COG0513	Belongs to the DEAD box helicase family
CWI26_RS03180	COG0673	inositol 2-dehydrogenase activity
CWI26_RS03190	COG1695	Transcriptional regulator
CWI26_RS03200	COG1956	GAF domain-containing protein
CWI26_RS03205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWI26_RS03220	COG1363	Peptidase, m42
CWI26_RS03230	COG2131	deaminase
CWI26_RS03240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CWI26_RS03245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWI26_RS03255	COG0024	Methionine aminopeptidase
CWI26_RS03265	COG2246	polysaccharide biosynthetic process
CWI26_RS03270	COG4708	membrane
CWI26_RS03275	COG0656	L-ascorbic acid biosynthetic process
CWI26_RS03280	COG2183	response to ionizing radiation
CWI26_RS03285	COG3091	SprT-like family
CWI26_RS03305	COG0732	type I restriction modification DNA specificity domain
CWI26_RS03320	COG4974	Belongs to the 'phage' integrase family
CWI26_RS03345	COG1482	cell wall glycoprotein biosynthetic process
CWI26_RS03350	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CWI26_RS03355	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CWI26_RS03370	COG1733	regulation of RNA biosynthetic process
CWI26_RS03375	COG0436	Aminotransferase
CWI26_RS03390	COG2205	protein histidine kinase activity
CWI26_RS03395	COG1136	(ABC) transporter
CWI26_RS03400	COG0577	efflux transmembrane transporter activity
CWI26_RS03425	COG1028	Short-chain dehydrogenase reductase Sdr
CWI26_RS03445	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CWI26_RS03450	COG0494	nUDIX hydrolase
CWI26_RS03475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CWI26_RS03495	COG1609	Transcriptional regulator
CWI26_RS03500	COG1653	transport
CWI26_RS03505	COG1175	transmembrane transport
CWI26_RS03510	COG0395	ABC-type sugar transport system, permease component
CWI26_RS03520	COG1674	ftsk spoiiie
CWI26_RS03520	COG0697	spore germination
CWI26_RS03525	COG0346	lactoylglutathione lyase activity
CWI26_RS03555	COG0625	glutathione transferase activity
CWI26_RS03560	COG2244	polysaccharide biosynthetic process
CWI26_RS03565	COG0528	UMP kinase activity
CWI26_RS03570	COG0233	cytoplasmic translational termination
CWI26_RS03575	COG2996	Protein conserved in bacteria
CWI26_RS03590	COG4479	Belongs to the UPF0346 family
CWI26_RS03595	COG3583	domain protein
CWI26_RS03600	COG1702	phosphate starvation-inducible protein PhoH
CWI26_RS03605	COG3590	peptidase
CWI26_RS03620	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CWI26_RS03630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CWI26_RS03635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CWI26_RS03650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWI26_RS03655	COG3022	response to hydroperoxide
CWI26_RS03660	COG1316	TRANSCRIPTIONal
CWI26_RS03665	COG3944	biosynthesis protein
CWI26_RS03675	COG4464	protein tyrosine phosphatase activity
CWI26_RS03685	COG3177	Filamentation induced by cAMP protein fic
CWI26_RS03690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWI26_RS03710	COG1442	glycosyl transferase family 8
CWI26_RS03710	COG1216	Glycosyl transferase, family 2
CWI26_RS03735	COG3475	LICD family
CWI26_RS03740	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CWI26_RS03775	COG4750	Nucleotidyl transferase
CWI26_RS03795	COG4372	Transposase
CWI26_RS03805	COG0562	UDP-galactopyranose mutase
CWI26_RS03810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CWI26_RS03825	COG0436	Aminotransferase
CWI26_RS03850	COG0251	oxidation-reduction process
CWI26_RS03855	COG1660	Displays ATPase and GTPase activities
CWI26_RS03860	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CWI26_RS03865	COG1481	regulation of sporulation
CWI26_RS03880	COG0454	-acetyltransferase
CWI26_RS03885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CWI26_RS03890	COG0549	Belongs to the carbamate kinase family
CWI26_RS03895	COG1288	antiporter activity
CWI26_RS03900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWI26_RS03910	COG1438	arginine binding
CWI26_RS03915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CWI26_RS03920	COG0363	glucosamine-6-phosphate deaminase activity
CWI26_RS03950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWI26_RS03955	COG1696	Membrane protein involved in D-alanine export
CWI26_RS03960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWI26_RS03965	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CWI26_RS03980	COG0435	Glutathione S-transferase
CWI26_RS03985	COG1187	pseudouridine synthase activity
CWI26_RS03990	COG0386	Belongs to the glutathione peroxidase family
CWI26_RS03995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWI26_RS04000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWI26_RS04005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWI26_RS04010	COG1120	ATPase activity
CWI26_RS04015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWI26_RS04020	COG0204	Acyl-transferase
CWI26_RS04025	COG1596	polysaccharide export
CWI26_RS04025	COG1555	photosystem II stabilization
CWI26_RS04030	COG0658	competence protein
CWI26_RS04030	COG2333	competence protein COMEC
CWI26_RS04040	COG1466	dna polymerase III delta subunit
CWI26_RS04045	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWI26_RS04050	COG0737	Belongs to the 5'-nucleotidase family
CWI26_RS04110	COG3561	AntA/AntB antirepressor
CWI26_RS04145	COG0556	nucleotide-excision repair
CWI26_RS04230	COG1475	DNA binding
CWI26_RS04360	COG0038	chloride channel
CWI26_RS04365	COG1605	Chorismate mutase
CWI26_RS04365	COG0287	Prephenate dehydrogenase
CWI26_RS04375	COG0716	FMN binding
CWI26_RS04380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CWI26_RS04400	COG0772	Belongs to the SEDS family
CWI26_RS04405	COG0693	protein deglycase activity
CWI26_RS04410	COG0187	DNA topoisomerase II activity
CWI26_RS04415	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CWI26_RS04420	COG0560	Phosphoserine phosphatase
CWI26_RS04470	COG2706	6-phosphogluconolactonase activity
CWI26_RS04475	COG0628	permease
CWI26_RS04485	COG3527	Alpha-acetolactate decarboxylase
CWI26_RS04490	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CWI26_RS04495	COG3711	transcriptional antiterminator
CWI26_RS04500	COG2190	(PTS) system
CWI26_RS04500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI26_RS04500	COG1263	PTS System
CWI26_RS04520	COG3842	ATPase activity
CWI26_RS04565	COG1442	glycosyl transferase family 8
CWI26_RS04565	COG1216	Glycosyl transferase, family 2
CWI26_RS04575	COG1442	glycosyl transferase family 8
CWI26_RS04575	COG1216	Glycosyl transferase, family 2
CWI26_RS04585	COG1215	transferase activity, transferring glycosyl groups
CWI26_RS04590	COG1442	glycosyl transferase family 8
CWI26_RS04595	COG1442	glycosyl transferase family 8
CWI26_RS04610	COG1215	transferase activity, transferring glycosyl groups
CWI26_RS04615	COG0201	protein transport
CWI26_RS04685	COG0488	(ABC) transporter
CWI26_RS04695	COG2226	methyltransferase
CWI26_RS04700	COG3442	glutamine amidotransferase
CWI26_RS04705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWI26_RS04720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWI26_RS04725	COG0488	(ABC) transporter
CWI26_RS04745	COG1573	uracil-dna glycosylase
CWI26_RS04755	COG1704	LemA family
CWI26_RS04765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CWI26_RS04770	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CWI26_RS04790	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CWI26_RS04795	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CWI26_RS04805	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CWI26_RS04810	COG0813	purine-nucleoside phosphorylase activity
CWI26_RS04815	COG0058	SHG alpha-glucan phosphorylase activity
CWI26_RS04830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWI26_RS04845	COG1216	Glycosyl transferase, family 2
CWI26_RS04860	COG1051	belongs to the nudix hydrolase family
CWI26_RS04865	COG0647	UMP catabolic process
CWI26_RS04875	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CWI26_RS04880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWI26_RS04885	COG1970	mechanosensitive ion channel activity
CWI26_RS04890	COG0358	DNA primase activity
CWI26_RS04895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWI26_RS04900	COG2151	metal-sulfur cluster biosynthetic enzyme
CWI26_RS04930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CWI26_RS04940	COG1131	(ABC) transporter
CWI26_RS04945	COG2188	Transcriptional regulator
CWI26_RS04955	COG0205	6-phosphofructokinase activity
CWI26_RS04960	COG0469	pyruvate kinase activity
CWI26_RS04980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI26_RS04985	COG2755	lipolytic protein G-D-S-L family
CWI26_RS04985	COG0657	acetylesterase activity
CWI26_RS04995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CWI26_RS05000	COG0765	amino acid transport
CWI26_RS05005	COG1126	abc transporter atp-binding protein
CWI26_RS05010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI26_RS05015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWI26_RS05030	COG1846	Transcriptional regulator
CWI26_RS05035	COG3759	membrane
CWI26_RS05070	COG2195	Cleaves the N-terminal amino acid of tripeptides
CWI26_RS05075	COG0561	phosphatase activity
CWI26_RS05095	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CWI26_RS05110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CWI26_RS05115	COG0196	riboflavin kinase activity
CWI26_RS05120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CWI26_RS05125	COG1393	Belongs to the ArsC family
CWI26_RS05130	COG4476	Belongs to the UPF0223 family
CWI26_RS05135	COG0483	inositol monophosphate 1-phosphatase activity
CWI26_RS05140	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CWI26_RS05140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWI26_RS05150	COG0573	inorganic phosphate transmembrane transporter activity
CWI26_RS05155	COG0581	inorganic phosphate transmembrane transporter activity
CWI26_RS05160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWI26_RS05165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWI26_RS05180	COG0745	RESPONSE REGULATOR receiver
CWI26_RS05185	COG5002	protein histidine kinase activity
CWI26_RS05200	COG1072	(Pantothenic acid kinase))
CWI26_RS05205	COG2813	Specifically methylates the guanine in position
CWI26_RS05210	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CWI26_RS05220	COG0295	cytidine deaminase activity
CWI26_RS05225	COG1744	ABC transporter substrate-binding protein PnrA-like
CWI26_RS05230	COG3845	ABC transporter
CWI26_RS05235	COG4603	Belongs to the binding-protein-dependent transport system permease family
CWI26_RS05240	COG1079	Belongs to the binding-protein-dependent transport system permease family
CWI26_RS05250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWI26_RS05255	COG0039	L-malate dehydrogenase activity
CWI26_RS05260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CWI26_RS05265	COG3764	Sortase (surface protein transpeptidase)
CWI26_RS05275	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CWI26_RS05280	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CWI26_RS05295	COG1104	cysteine desulfurase activity
CWI26_RS05305	COG4116	CYTH
CWI26_RS05310	COG2357	RelA SpoT domain protein
CWI26_RS05315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CWI26_RS05320	COG0564	pseudouridine synthase activity
CWI26_RS05325	COG0280	phosphate acetyltransferase
CWI26_RS05330	COG1132	(ABC) transporter
CWI26_RS05335	COG1132	(ABC) transporter
CWI26_RS05345	COG1194	a g-specific adenine glycosylase
CWI26_RS05350	COG1396	sequence-specific DNA binding
CWI26_RS05365	COG1454	alcohol dehydrogenase
CWI26_RS05370	COG2873	o-acetylhomoserine
CWI26_RS05375	COG0488	(ABC) transporter
CWI26_RS05380	COG0456	acetyltransferase
CWI26_RS05385	COG1126	abc transporter atp-binding protein
CWI26_RS05415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI26_RS05420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI26_RS05445	COG0297	glycogen (starch) synthase activity
CWI26_RS05455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CWI26_RS05470	COG0167	dihydroorotate dehydrogenase activity
CWI26_RS05475	COG0284	orotidine-5'-phosphate decarboxylase activity
CWI26_RS05480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CWI26_RS05495	COG0463	Glycosyl transferase, family 2
CWI26_RS05500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CWI26_RS05530	COG0737	Belongs to the 5'-nucleotidase family
CWI26_RS05535	COG0424	maF-like protein
CWI26_RS05560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CWI26_RS05565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWI26_RS05575	COG0534	Mate efflux family protein
CWI26_RS05580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CWI26_RS05585	COG0336	Belongs to the RNA methyltransferase TrmD family
CWI26_RS05590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CWI26_RS05595	COG1349	DNA-binding transcription factor activity
CWI26_RS05600	COG1105	Belongs to the carbohydrate kinase PfkB family
CWI26_RS05605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI26_RS05605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWI26_RS05605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWI26_RS05610	COG3583	domain protein
CWI26_RS05620	COG1307	EDD domain protein, DegV family
CWI26_RS05625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CWI26_RS05630	COG0617	tRNA 3'-terminal CCA addition
CWI26_RS05635	COG0488	(ABC) transporter
CWI26_RS05645	COG1940	carbohydrate kinase activity
CWI26_RS05660	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CWI26_RS05665	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWI26_RS05675	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CWI26_RS05690	COG0481	GTPase activity
CWI26_RS05715	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CWI26_RS05720	COG2890	protein-(glutamine-N5) methyltransferase activity
CWI26_RS05725	COG0009	L-threonylcarbamoyladenylate synthase
CWI26_RS05735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CWI26_RS05745	COG0741	lytic transglycosylase activity
CWI26_RS05755	COG4221	oxidoreductase activity
CWI26_RS05780	COG1396	sequence-specific DNA binding
CWI26_RS05780	COG3800	Transcriptional regulator
CWI26_RS05800	COG2188	Transcriptional regulator
CWI26_RS05805	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CWI26_RS05810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CWI26_RS05830	COG4974	Belongs to the 'phage' integrase family
CWI26_RS05840	COG5002	protein histidine kinase activity
CWI26_RS05845	COG0745	RESPONSE REGULATOR receiver
CWI26_RS05860	COG0577	efflux transmembrane transporter activity
CWI26_RS05865	COG1136	(ABC) transporter
CWI26_RS05890	COG2382	esterase
CWI26_RS05895	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CWI26_RS05900	COG0647	UMP catabolic process
CWI26_RS05905	COG4974	Belongs to the 'phage' integrase family
CWI26_RS05915	COG1396	sequence-specific DNA binding
CWI26_RS05945	COG0745	RESPONSE REGULATOR receiver
CWI26_RS05950	COG2205	protein histidine kinase activity
CWI26_RS05955	COG3843	relaxase mobilization nuclease domain protein
CWI26_RS05985	COG0542	response to heat
CWI26_RS05990	COG1396	sequence-specific DNA binding
CWI26_RS06065	COG4443	Transcriptional Coactivator p15 (PC4)
CWI26_RS06070	COG1475	DNA binding
CWI26_RS06230	COG1192	Involved in chromosome partitioning
CWI26_RS06280	COG0270	DNA (cytosine-5-)-methyltransferase activity
CWI26_RS06300	COG0222	ribosome binding
CWI26_RS06305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CWI26_RS06310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWI26_RS06315	COG0758	DNA mediated transformation
CWI26_RS06320	COG0110	maltose O-acetyltransferase activity
CWI26_RS06325	COG0425	Belongs to the sulfur carrier protein TusA family
CWI26_RS06325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CWI26_RS06335	COG1272	protein, Hemolysin III
CWI26_RS06350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CWI26_RS06355	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWI26_RS06360	COG0582	viral genome integration into host DNA
CWI26_RS06370	COG1940	carbohydrate kinase activity
CWI26_RS06385	COG0395	ABC-type sugar transport system, permease component
CWI26_RS06390	COG1175	transmembrane transport
CWI26_RS06410	COG1070	Carbohydrate kinase
CWI26_RS06435	COG0038	chloride channel
CWI26_RS06445	COG1177	transmembrane transport
CWI26_RS06450	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWI26_RS06460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CWI26_RS06465	COG0083	homoserine kinase activity
CWI26_RS06470	COG0460	homoserine dehydrogenase
CWI26_RS06475	COG0726	polysaccharide deacetylase
CWI26_RS06480	COG1132	(ABC) transporter
CWI26_RS06495	COG0228	four-way junction DNA binding
CWI26_RS06510	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CWI26_RS06515	COG2521	methyltransferase
CWI26_RS06515	COG2136	Putative SAM-dependent methyltransferase
CWI26_RS06525	COG0505	Belongs to the CarA family
CWI26_RS06530	COG0540	Belongs to the ATCase OTCase family
CWI26_RS06535	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CWI26_RS06545	COG2824	Alkylphosphonate utilization operon protein PhnA
CWI26_RS06560	COG0564	pseudouridine synthase activity
CWI26_RS06580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CWI26_RS06585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CWI26_RS06595	COG1114	Component of the transport system for branched-chain amino acids
CWI26_RS06600	COG0301	tRNA thio-modification
CWI26_RS06605	COG1104	cysteine desulfurase activity
CWI26_RS06640	COG0539	negative regulation of cytoplasmic translation
CWI26_RS06660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWI26_RS06675	COG2184	nucleotidyltransferase activity
CWI26_RS06680	COG0187	DNA topoisomerase II activity
CWI26_RS06690	COG1074	ATP-dependent DNA helicase activity
CWI26_RS06695	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CWI26_RS06765	COG1131	(ABC) transporter
CWI26_RS06800	COG1011	Hydrolase
CWI26_RS06810	COG0210	DNA helicase
CWI26_RS06815	COG3177	Filamentation induced by cAMP protein fic
CWI26_RS06830	COG1164	Oligoendopeptidase f
CWI26_RS06840	COG0346	lactoylglutathione lyase activity
CWI26_RS06845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWI26_RS06850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CWI26_RS06855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CWI26_RS06865	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWI26_RS06870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWI26_RS06875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CWI26_RS06900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWI26_RS06910	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CWI26_RS06920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWI26_RS06925	COG4684	Psort location CytoplasmicMembrane, score
CWI26_RS06930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWI26_RS07020	COG3620	sequence-specific DNA binding
CWI26_RS07090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWI26_RS07100	COG0500	methyltransferase
CWI26_RS07110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWI26_RS07120	COG0077	Prephenate dehydratase
CWI26_RS07125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CWI26_RS07135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWI26_RS07140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWI26_RS07145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CWI26_RS07150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CWI26_RS07160	COG1116	anion transmembrane transporter activity
CWI26_RS07160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWI26_RS07165	COG4120	Belongs to the binding-protein-dependent transport system permease family
CWI26_RS07195	COG3684	Belongs to the aldolase LacD family
CWI26_RS07205	COG3679	Belongs to the UPF0342 family
CWI26_RS07210	COG0287	Prephenate dehydrogenase
CWI26_RS07215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CWI26_RS07220	COG0710	3-dehydroquinate dehydratase activity
CWI26_RS07225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CWI26_RS07230	COG1368	sulfuric ester hydrolase activity
CWI26_RS07245	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CWI26_RS07255	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CWI26_RS07280	COG0463	Glycosyl transferase, family 2
CWI26_RS07285	COG0463	Glycosyl transferase, family 2
CWI26_RS07330	COG1216	Glycosyl transferase, family 2
CWI26_RS07330	COG1442	glycosyl transferase family 8
CWI26_RS07355	COG1091	dTDP-4-dehydrorhamnose reductase activity
CWI26_RS07360	COG1088	dTDP-glucose 4,6-dehydratase activity
CWI26_RS07375	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CWI26_RS07385	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CWI26_RS07390	COG2384	SAM-dependent methyltransferase
CWI26_RS07405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWI26_RS07425	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CWI26_RS07425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CWI26_RS07430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWI26_RS07435	COG2217	Heavy metal translocating P-type atpase
CWI26_RS07440	COG0300	oxidoreductase activity
CWI26_RS07445	COG1234	tRNA 3'-trailer cleavage
CWI26_RS07455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CWI26_RS07460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CWI26_RS07470	COG2807	transmembrane transport
CWI26_RS07475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CWI26_RS07480	COG2610	gluconate transmembrane transporter activity
CWI26_RS07500	COG0302	gtp cyclohydrolase
CWI26_RS07505	COG1051	belongs to the nudix hydrolase family
CWI26_RS07530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWI26_RS07530	COG0072	phenylalanine-tRNA ligase activity
CWI26_RS07555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWI26_RS07565	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CWI26_RS07570	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CWI26_RS07575	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CWI26_RS07580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CWI26_RS07585	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWI26_RS07590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CWI26_RS07595	COG0356	it plays a direct role in the translocation of protons across the membrane
CWI26_RS07605	COG1597	lipid kinase activity
CWI26_RS07615	COG0701	Predicted permease
CWI26_RS07620	COG3689	TIGRFAM TIGR03943 family protein
CWI26_RS07625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CWI26_RS07645	COG0552	protein localization to endoplasmic reticulum
CWI26_RS07650	COG0561	phosphatase activity
CWI26_RS07655	COG0561	phosphatase activity
CWI26_RS07660	COG1196	nuclear chromosome segregation
CWI26_RS07705	COG1012	belongs to the aldehyde dehydrogenase family
CWI26_RS07715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI26_RS07720	COG0538	isocitrate dehydrogenase activity
CWI26_RS07725	COG0372	Belongs to the citrate synthase family
CWI26_RS07735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CWI26_RS07740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWI26_RS07750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWI26_RS07785	COG1476	TRANSCRIPTIONal
CWI26_RS07805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CWI26_RS07815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWI26_RS07820	COG4122	O-methyltransferase activity
CWI26_RS07850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWI26_RS07850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWI26_RS07900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWI26_RS07920	COG0531	amino acid
CWI26_RS07930	COG0708	Exodeoxyribonuclease III
CWI26_RS07970	COG1393	Belongs to the ArsC family
CWI26_RS07975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWI26_RS07980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWI26_RS07990	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CWI26_RS08000	COG4467	Involved in initiation control of chromosome replication
CWI26_RS08005	COG0470	DNA polymerase III
CWI26_RS08010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CWI26_RS08015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWI26_RS08030	COG0517	IMP dehydrogenase activity
CWI26_RS08065	COG0683	leucine binding
CWI26_RS08100	COG4372	Transposase
CWI26_RS08105	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CWI26_RS08110	COG0366	Alpha amylase catalytic
CWI26_RS08115	COG0366	Alpha amylase catalytic
CWI26_RS08130	COG0395	ABC-type sugar transport system, permease component
CWI26_RS08135	COG1175	transmembrane transport
CWI26_RS08140	COG1653	transport
CWI26_RS08165	COG2207	Transcriptional regulator
CWI26_RS08170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CWI26_RS08175	COG0626	cystathionine gamma-synthase activity
CWI26_RS08195	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CWI26_RS08200	COG2827	Endonuclease containing a URI domain
CWI26_RS08220	COG0640	Transcriptional regulator
CWI26_RS08225	COG0513	Belongs to the DEAD box helicase family
CWI26_RS08235	COG0823	Involved in the tonB-independent uptake of proteins
CWI26_RS08265	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWI26_RS08275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWI26_RS08300	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWI26_RS08305	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CWI26_RS08310	COG0768	penicillin binding
CWI26_RS08315	COG0488	(ABC) transporter
CWI26_RS08325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CWI26_RS08335	COG0745	RESPONSE REGULATOR receiver
CWI26_RS08340	COG1126	abc transporter atp-binding protein
CWI26_RS08345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI26_RS08350	COG0765	amino acid transport
CWI26_RS08355	COG0765	amino acid transport
CWI26_RS08370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CWI26_RS08385	COG0438	transferase activity, transferring glycosyl groups
CWI26_RS08400	COG1609	Transcriptional regulator
CWI26_RS08410	COG0343	queuine tRNA-ribosyltransferase activity
CWI26_RS08425	COG1832	CoA-binding protein
CWI26_RS08435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWI26_RS08435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWI26_RS08475	COG1131	(ABC) transporter
CWI26_RS08510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CWI26_RS08515	COG0583	DNA-binding transcription factor activity
CWI26_RS08520	COG0110	maltose O-acetyltransferase activity
CWI26_RS08525	COG2217	Heavy metal translocating P-type atpase
CWI26_RS08535	COG1063	alcohol dehydrogenase
CWI26_RS08540	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CWI26_RS08545	COG0557	exoribonuclease II activity
CWI26_RS08550	COG0017	Asparaginyl-tRNA synthetase
CWI26_RS08560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWI26_RS08565	COG2814	Major facilitator Superfamily
CWI26_RS08575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CWI26_RS08585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CWI26_RS08590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CWI26_RS08600	COG1737	Transcriptional regulator
CWI26_RS08605	COG2190	(PTS) system
CWI26_RS08605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI26_RS08605	COG1263	PTS System
CWI26_RS08625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWI26_RS08640	COG0395	ABC-type sugar transport system, permease component
CWI26_RS08645	COG1175	transmembrane transport
CWI26_RS08665	COG1132	(ABC) transporter
CWI26_RS08670	COG1132	(ABC) transporter
CWI26_RS08705	COG2177	Part of the ABC transporter FtsEX involved in
CWI26_RS08710	COG2884	Cell division ATP-binding protein ftsE
CWI26_RS08720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CWI26_RS08755	COG1078	dGTPase activity
CWI26_RS08765	COG0149	triose-phosphate isomerase activity
CWI26_RS08770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CWI26_RS08785	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CWI26_RS08790	COG0772	Belongs to the SEDS family
CWI26_RS08810	COG3859	Proton-coupled thiamine transporter YuaJ
CWI26_RS08820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CWI26_RS08830	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CWI26_RS08850	COG0577	efflux transmembrane transporter activity
CWI26_RS08855	COG1136	(ABC) transporter
CWI26_RS08860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI26_RS08865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWI26_RS08870	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CWI26_RS08875	COG1268	BioY protein
CWI26_RS08880	COG4443	Transcriptional Coactivator p15 (PC4)
CWI26_RS08890	COG0826	peptidase U32
CWI26_RS08910	COG0789	Transcriptional regulator
CWI26_RS08935	COG1227	inorganic diphosphatase activity
CWI26_RS08945	COG1733	regulation of RNA biosynthetic process
CWI26_RS08970	COG2514	catechol 2,3-dioxygenase activity
CWI26_RS08975	COG1472	Belongs to the glycosyl hydrolase 3 family
CWI26_RS08980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CWI26_RS08985	COG1253	flavin adenine dinucleotide binding
CWI26_RS08990	COG1119	ATPase activity
CWI26_RS08995	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CWI26_RS09015	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CWI26_RS09020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CWI26_RS09025	COG0133	tryptophan synthase activity
CWI26_RS09050	COG4470	Protein conserved in bacteria
CWI26_RS09055	COG3480	Lon protease (S16) C-terminal proteolytic domain
CWI26_RS09060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CWI26_RS09065	COG0742	ribosomal rna small subunit methyltransferase
CWI26_RS09075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CWI26_RS09080	COG4483	Protein conserved in bacteria
CWI26_RS09085	COG2197	response regulator
CWI26_RS09090	COG4585	Histidine kinase
CWI26_RS09095	COG0842	Transport permease protein
CWI26_RS09100	COG1131	(ABC) transporter
CWI26_RS09115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWI26_RS09125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWI26_RS09125	COG2755	lipolytic protein G-D-S-L family
CWI26_RS09130	COG0671	phosphoesterase, PA-phosphatase related
CWI26_RS09135	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CWI26_RS09145	COG0747	negative chemotaxis
CWI26_RS09150	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CWI26_RS09155	COG1187	pseudouridine synthase activity
CWI26_RS09160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CWI26_RS09165	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CWI26_RS09170	COG0582	viral genome integration into host DNA
CWI26_RS09190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CWI26_RS09195	COG3763	UPF0154 protein
CWI26_RS09205	COG3579	cysteine-type endopeptidase activity
CWI26_RS09230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWI26_RS09235	COG1254	Belongs to the acylphosphatase family
CWI26_RS09245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWI26_RS09250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWI26_RS09270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CWI26_RS09280	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWI26_RS09295	COG1160	GTP binding
CWI26_RS09305	COG1484	DNA-dependent DNA replication
CWI26_RS09315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CWI26_RS09325	COG1131	(ABC) transporter
CWI26_RS09360	COG0628	permease
CWI26_RS09365	COG0745	RESPONSE REGULATOR receiver
CWI26_RS09370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CWI26_RS09380	COG0492	ferredoxin-NADP+ reductase activity
CWI26_RS09390	COG0513	Belongs to the DEAD box helicase family
CWI26_RS09405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWI26_RS09410	COG0768	penicillin binding
CWI26_RS09420	COG0275	rRNA processing
CWI26_RS09475	COG4939	FMN-binding domain protein
CWI26_RS09480	COG0142	geranyltranstransferase activity
CWI26_RS09485	COG1252	NADH dehydrogenase
CWI26_RS09500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWI26_RS09505	COG0569	domain protein
CWI26_RS09510	COG0534	Mate efflux family protein
CWI26_RS09520	COG4224	UPF0291 protein
CWI26_RS09525	COG0751	glycine-tRNA ligase activity
CWI26_RS09550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWI26_RS09555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWI26_RS09560	COG1464	Belongs to the NlpA lipoprotein family
CWI26_RS09570	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CWI26_RS09575	COG4608	Belongs to the ABC transporter superfamily
CWI26_RS09580	COG0444	Belongs to the ABC transporter superfamily
CWI26_RS09585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWI26_RS09590	COG0601	transmembrane transport
CWI26_RS09600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CWI26_RS09605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CWI26_RS09610	COG2252	PERMEase
CWI26_RS09615	COG0561	phosphatase activity
CWI26_RS09625	COG3715	PTS system
CWI26_RS09630	COG3716	PTS system mannose fructose sorbose family IID component
CWI26_RS09655	COG3177	Filamentation induced by cAMP protein fic
CWI26_RS09665	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CWI26_RS09715	COG0439	Biotin carboxylase
CWI26_RS09735	COG1028	Short-chain dehydrogenase reductase Sdr
CWI26_RS09740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWI26_RS09745	COG2070	2-Nitropropane dioxygenase
CWI26_RS09755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWI26_RS09765	COG1024	Enoyl-CoA hydratase
CWI26_RS09770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWI26_RS09775	COG0527	aspartate kinase activity
CWI26_RS09785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWI26_RS09790	COG0736	holo-[acyl-carrier-protein] synthase activity
CWI26_RS09795	COG0653	protein targeting
CWI26_RS09820	COG1940	carbohydrate kinase activity
CWI26_RS09825	COG2190	(PTS) system
CWI26_RS09825	COG1263	PTS System
CWI26_RS09825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI26_RS09830	COG1621	beta-fructofuranosidase activity
CWI26_RS09835	COG1609	Transcriptional regulator
CWI26_RS09840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWI26_RS09855	COG0006	proline dipeptidase activity
CWI26_RS09900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CWI26_RS09925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CWI26_RS09930	COG0629	single-stranded DNA binding
CWI26_RS09940	COG0095	Lipoate-protein ligase
CWI26_RS09945	COG2723	6-phospho-beta-galactosidase activity
CWI26_RS09960	COG2723	6-phospho-beta-galactosidase activity
CWI26_RS09965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI26_RS09975	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWI26_RS09980	COG3711	transcriptional antiterminator
CWI26_RS09980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI26_RS09995	COG4095	Psort location CytoplasmicMembrane, score
CWI26_RS10000	COG2723	6-phospho-beta-galactosidase activity
CWI26_RS10005	COG0346	lactoylglutathione lyase activity
CWI26_RS10010	COG2723	6-phospho-beta-galactosidase activity
CWI26_RS10015	COG2207	Transcriptional regulator
CWI26_RS10045	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWI26_RS10050	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWI26_RS10050	COG0022	dehydrogenase e1 component
CWI26_RS10055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CWI26_RS10060	COG2860	membrane
CWI26_RS10075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CWI26_RS10080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CWI26_RS10090	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CWI26_RS10095	COG0195	Participates in both transcription termination and antitermination
CWI26_RS10105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CWI26_RS10115	COG4473	ABC transporter
CWI26_RS10120	COG1131	(ABC) transporter
CWI26_RS10125	COG0537	adenosine 5'-monophosphoramidase activity
CWI26_RS10140	COG1316	TRANSCRIPTIONal
CWI26_RS10150	COG0802	atpase or kinase
CWI26_RS10155	COG1461	Dihydroxyacetone kinase
CWI26_RS10165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWI26_RS10170	COG0601	transmembrane transport
CWI26_RS10175	COG4608	Belongs to the ABC transporter superfamily
CWI26_RS10190	COG1686	Belongs to the peptidase S11 family
CWI26_RS10205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWI26_RS10210	COG0719	Fe-S assembly protein
CWI26_RS10225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWI26_RS10230	COG4862	establishment of competence for transformation
CWI26_RS10235	COG1968	undecaprenyl-diphosphatase activity
CWI26_RS10240	COG0765	amino acid transport
CWI26_RS10245	COG1126	abc transporter atp-binding protein
CWI26_RS10260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWI26_RS10265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CWI26_RS10270	COG0440	acetolactate synthase activity
CWI26_RS10275	COG0028	Belongs to the TPP enzyme family
CWI26_RS10280	COG0463	Glycosyl transferase, family 2
CWI26_RS10295	COG0129	dihydroxy-acid dehydratase activity
CWI26_RS10300	COG1442	glycosyl transferase family 8
CWI26_RS10310	COG2151	metal-sulfur cluster biosynthetic enzyme
CWI26_RS10350	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CWI26_RS10375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWI26_RS10400	COG3842	ATPase activity
CWI26_RS10410	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CWI26_RS10430	COG1045	serine acetyltransferase
CWI26_RS10435	COG1185	polyribonucleotide nucleotidyltransferase activity
CWI26_RS10450	COG1132	(ABC) transporter
CWI26_RS10455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CWI26_RS10485	COG0464	growth
CWI26_RS10495	COG1187	pseudouridine synthase activity
CWI26_RS10515	COG0242	peptide deformylase activity
CWI26_RS10535	COG1136	(ABC) transporter
CWI26_RS10550	COG0066	3-isopropylmalate dehydratase activity
CWI26_RS10560	COG0473	3-isopropylmalate dehydrogenase activity
CWI26_RS10575	COG2309	aminopeptidase activity
CWI26_RS10585	COG2176	DNA-directed DNA polymerase activity
CWI26_RS10590	COG2376	Dihydroxyacetone kinase
CWI26_RS10600	COG2376	Dihydroxyacetone kinase
CWI26_RS10605	COG1461	Dihydroxyacetone kinase
CWI26_RS10610	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CWI26_RS10615	COG0442	prolyl-tRNA aminoacylation
CWI26_RS10625	COG4589	Belongs to the CDS family
CWI26_RS10630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWI26_RS10635	COG1862	Preprotein translocase
CWI26_RS10645	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWI26_RS10645	COG2918	glutathione biosynthetic process
CWI26_RS10655	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CWI26_RS10660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWI26_RS10665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CWI26_RS10715	COG0454	-acetyltransferase
CWI26_RS10720	COG0542	response to heat
CWI26_RS10725	COG4463	regulation of RNA biosynthetic process
CWI26_RS10745	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CWI26_RS10780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWI26_RS10785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWI26_RS10790	COG0492	ferredoxin-NADP+ reductase activity
CWI26_RS10795	COG0564	pseudouridine synthase activity
CWI26_RS10820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWI26_RS10840	COG1564	THIamine pyrophosphokinase
CWI26_RS10850	COG1162	GTPase activity
CWI26_RS10880	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CWI26_RS10885	COG1132	(ABC) transporter
CWI26_RS10915	COG4115	mRNA cleavage
CWI26_RS10950	COG0084	hydrolase, TatD family'
CWI26_RS10960	COG1847	R3H domain protein
CWI26_RS10970	COG0594	ribonuclease P activity
CWI26_RS10975	COG0165	Argininosuccinate lyase
CWI26_RS10980	COG0137	argininosuccinate synthase activity
CWI26_RS10995	COG2040	homocysteine
CWI26_RS11000	COG0833	amino acid
CWI26_RS11040	COG3764	Sortase (surface protein transpeptidase)
CWI26_RS11075	COG0756	dUTP diphosphatase activity
CWI26_RS11080	COG2832	Protein of unknown function (DUF454)
CWI26_RS11090	COG1053	succinate dehydrogenase
CWI26_RS11090	COG0431	NADPH-dependent FMN reductase
CWI26_RS11090	COG3976	FMN-binding domain protein
CWI26_RS11100	COG1132	(ABC) transporter
CWI26_RS11105	COG1132	(ABC) transporter
CWI26_RS11125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CWI26_RS11130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CWI26_RS11135	COG0705	Rhomboid family
CWI26_RS11140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CWI26_RS11145	COG1473	amidohydrolase
CWI26_RS11150	COG2171	N-acyltransferase activity
CWI26_RS11155	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CWI26_RS11180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CWI26_RS11205	COG3623	hexulose-6-phosphate isomerase
CWI26_RS11230	COG1523	belongs to the glycosyl hydrolase 13 family
CWI26_RS11240	COG1609	Transcriptional regulator
CWI26_RS11245	COG1126	abc transporter atp-binding protein
CWI26_RS11250	COG0765	amino acid transport
CWI26_RS11255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI26_RS11260	COG3942	CHAP domain
CWI26_RS11265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI26_RS11275	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWI26_RS11285	COG3711	transcriptional antiterminator
CWI26_RS11285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI26_RS11295	COG2723	6-phospho-beta-galactosidase activity
CWI26_RS11300	COG1486	melibiose metabolic process
CWI26_RS11310	COG4667	esterase of the alpha-beta hydrolase superfamily
CWI26_RS11315	COG3590	peptidase
CWI26_RS11320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWI26_RS11325	COG1321	iron dependent repressor
CWI26_RS11325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWI26_RS11330	COG1121	(ABC) transporter
CWI26_RS11345	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWI26_RS11430	COG3290	protein histidine kinase activity
CWI26_RS11450	COG1490	D-aminoacyl-tRNA deacylase activity
CWI26_RS11460	COG0737	Belongs to the 5'-nucleotidase family
CWI26_RS11470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CWI26_RS11495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWI26_RS11530	COG1328	CTP reductase activity
CWI26_RS11555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWI26_RS11580	COG1438	arginine binding
CWI26_RS11585	COG0018	arginyl-trna synthetase
CWI26_RS11605	COG1640	4-alpha-glucanotransferase
CWI26_RS11610	COG2182	Extracellular solute-binding protein
CWI26_RS11615	COG1175	transmembrane transport
CWI26_RS11620	COG3833	ABC-type maltose transport systems, permease component
CWI26_RS11625	COG5521	maltodextrose utilization protein MalA
CWI26_RS11630	COG1609	Transcriptional regulator
CWI26_RS11635	COG1523	belongs to the glycosyl hydrolase 13 family
CWI26_RS11640	COG1780	Probably involved in ribonucleotide reductase function
CWI26_RS11645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWI26_RS11650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CWI26_RS11655	COG2153	protein acetylation
CWI26_RS11660	COG4989	oxidoreductase activity
CWI26_RS11665	COG1216	Glycosyl transferase, family 2
CWI26_RS11685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CWI26_RS11695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWI26_RS11700	COG0785	Cytochrome C biogenesis protein
CWI26_RS11710	COG0305	Participates in initiation and elongation during chromosome replication
CWI26_RS11715	COG0359	binds to the 23S rRNA
CWI26_RS11725	COG0445	tRNA wobble uridine modification
CWI26_RS11740	COG1051	belongs to the nudix hydrolase family
CWI26_RS11755	COG1733	regulation of RNA biosynthetic process
CWI26_RS11765	COG0482	sulfurtransferase activity
CWI26_RS11770	COG1760	l-serine dehydratase
CWI26_RS11775	COG1760	l-serine dehydratase
CWI26_RS11785	COG0745	RESPONSE REGULATOR receiver
CWI26_RS11790	COG3850	Histidine kinase
CWI26_RS11790	COG5002	protein histidine kinase activity
CWI26_RS11800	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CWI26_RS11805	COG1122	ATPase activity
CWI26_RS11810	COG1122	ATPase activity
CWI26_RS11815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWI26_RS11820	COG1426	Protein conserved in bacteria
CWI26_RS11825	COG0612	Peptidase, M16
CWI26_RS11830	COG0612	Peptidase, M16
CWI26_RS11840	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CWI26_RS11845	COG0516	GMP reductase activity
CWI26_RS11845	COG0517	IMP dehydrogenase activity
CWI26_RS11855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWI26_RS11860	COG0488	(ABC) transporter
CWI26_RS11880	COG4372	Transposase
CWI26_RS11905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CWI26_RS11910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWI26_RS11915	COG1475	DNA binding