locus-tag	class	description
CR541_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CR541_RS00010	COG0592	DNA-directed DNA polymerase activity
CR541_RS00030	COG0012	GTP binding
CR541_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
CR541_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CR541_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CR541_RS00065	COG0037	tRNA processing
CR541_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CR541_RS00190	COG1792	Involved in formation and maintenance of cell shape
CR541_RS00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CR541_RS00210	COG0436	Aminotransferase
CR541_RS00215	COG1381	Involved in DNA repair and RecF pathway recombination
CR541_RS00220	COG0416	fatty acid biosynthetic process
CR541_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CR541_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CR541_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CR541_RS00255	COG0138	bifunctional purine biosynthesis protein purh
CR541_RS00260	COG0151	Belongs to the GarS family
CR541_RS00265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CR541_RS00285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CR541_RS00310	COG1131	(ABC) transporter
CR541_RS00320	COG1132	(ABC) transporter
CR541_RS00325	COG2255	four-way junction helicase activity
CR541_RS00335	COG0546	phosphoglycolate phosphatase activity
CR541_RS00360	COG0285	dihydrofolate synthase activity
CR541_RS00375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CR541_RS00380	COG0632	four-way junction helicase activity
CR541_RS00395	COG0519	Catalyzes the synthesis of GMP from XMP
CR541_RS00410	COG1393	Belongs to the ArsC family
CR541_RS00415	COG4472	Bacterial protein of unknown function (DUF965)
CR541_RS00420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CR541_RS00425	COG3906	Belongs to the UPF0473 family
CR541_RS00445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CR541_RS00450	COG0088	Forms part of the polypeptide exit tunnel
CR541_RS00455	COG0089	rRNA binding
CR541_RS00460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CR541_RS00465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CR541_RS00470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CR541_RS00475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CR541_RS00480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CR541_RS00485	COG0255	Belongs to the universal ribosomal protein uL29 family
CR541_RS00490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CR541_RS00495	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CR541_RS00500	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CR541_RS00505	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CR541_RS00510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CR541_RS00520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CR541_RS00530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CR541_RS00535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CR541_RS00540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CR541_RS00545	COG1841	ribosomal large subunit assembly
CR541_RS00555	COG0201	protein transport
CR541_RS00560	COG0563	adenylate kinase activity
CR541_RS00565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CR541_RS00570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CR541_RS00575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CR541_RS00585	COG0202	RNA polymerase activity
CR541_RS00675	COG0582	viral genome integration into host DNA
CR541_RS00685	COG2946	Replication initiation factor
CR541_RS00730	COG1121	(ABC) transporter
CR541_RS00735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CR541_RS00740	COG3443	Belongs to the bacterial solute-binding protein 9 family
CR541_RS00740	COG0803	Belongs to the bacterial solute-binding protein 9 family
CR541_RS00770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR541_RS00775	COG0085	RNA polymerase activity
CR541_RS00780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CR541_RS00795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CR541_RS00800	COG1459	type II secretion system
CR541_RS00805	COG4537	Required for transformation and DNA binding
CR541_RS00835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CR541_RS00845	COG0285	dihydrofolate synthase activity
CR541_RS00850	COG1363	Peptidase, m42
CR541_RS00865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CR541_RS00875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR541_RS00900	COG0459	protein refolding
CR541_RS00910	COG0049	tRNA binding
CR541_RS00915	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CR541_RS00925	COG3590	peptidase
CR541_RS00935	COG0126	phosphoglycerate kinase activity
CR541_RS00945	COG0789	Transcriptional regulator
CR541_RS00950	COG0174	glutamine synthetase
CR541_RS00965	COG1214	PFAM Peptidase M22, glycoprotease
CR541_RS00975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CR541_RS00980	COG2207	Transcriptional regulator
CR541_RS00990	COG1175	transmembrane transport
CR541_RS00995	COG0395	ABC-type sugar transport system, permease component
CR541_RS01015	COG2855	membrane
CR541_RS01040	COG1131	(ABC) transporter
CR541_RS01045	COG2081	HI0933 family
CR541_RS01050	COG2723	6-phospho-beta-galactosidase activity
CR541_RS01060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR541_RS01075	COG3959	Transketolase, thiamine diphosphate binding domain
CR541_RS01080	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CR541_RS01085	COG0584	glycerophosphoryl diester phosphodiesterase
CR541_RS01090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CR541_RS01095	COG2222	sugar isomerase
CR541_RS01125	COG1882	Formate acetyltransferase
CR541_RS01140	COG2910	NAD(P)H-binding
CR541_RS01165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR541_RS01200	COG0363	glucosamine-6-phosphate deaminase activity
CR541_RS01210	COG2217	Heavy metal translocating P-type atpase
CR541_RS01215	COG2217	Heavy metal translocating P-type atpase
CR541_RS01220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CR541_RS01225	COG0681	Belongs to the peptidase S26 family
CR541_RS01250	COG0366	Alpha amylase catalytic
CR541_RS01255	COG1263	PTS System
CR541_RS01255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR541_RS01260	COG2188	Transcriptional regulator
CR541_RS01275	COG1193	negative regulation of DNA recombination
CR541_RS01285	COG3118	belongs to the thioredoxin family
CR541_RS01290	COG0318	PFAM AMP-dependent synthetase and ligase
CR541_RS01295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CR541_RS01295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CR541_RS01320	COG1115	amino acid carrier protein
CR541_RS01325	COG0668	transmembrane transport
CR541_RS01340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CR541_RS01345	COG0167	dihydroorotate dehydrogenase activity
CR541_RS01350	COG2843	Capsule synthesis protein
CR541_RS01355	COG0561	phosphatase activity
CR541_RS01370	COG1131	(ABC) transporter
CR541_RS01375	COG1309	transcriptional regulator
CR541_RS01380	COG1511	domain protein
CR541_RS01405	COG1346	cytolysis
CR541_RS01410	COG2116	formate transmembrane transporter activity
CR541_RS01415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CR541_RS01420	COG0433	COG0433 Predicted ATPase
CR541_RS01425	COG0494	nUDIX hydrolase
CR541_RS01450	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CR541_RS01455	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CR541_RS01460	COG0124	histidyl-tRNA synthetase
CR541_RS01465	COG1064	alcohol dehydrogenase
CR541_RS01470	COG1454	alcohol dehydrogenase
CR541_RS01470	COG1012	belongs to the aldehyde dehydrogenase family
CR541_RS01480	COG4988	ABC transporter
CR541_RS01485	COG1132	(ABC) transporter
CR541_RS01500	COG1129	ABC transporter
CR541_RS01505	COG0534	Mate efflux family protein
CR541_RS01510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CR541_RS01525	COG1304	FMN binding
CR541_RS01530	COG1132	(ABC) transporter
CR541_RS01535	COG1132	(ABC) transporter
CR541_RS01540	COG3830	Belongs to the UPF0237 family
CR541_RS01545	COG2848	UPF0210 protein
CR541_RS01550	COG0588	phosphoglycerate mutase activity
CR541_RS01555	COG1420	regulation of RNA biosynthetic process
CR541_RS01560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CR541_RS01565	COG0443	Heat shock 70 kDa protein
CR541_RS01570	COG0484	heat shock protein binding
CR541_RS01580	COG0095	Lipoate-protein ligase
CR541_RS01590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR541_RS01595	COG0765	amino acid transport
CR541_RS01600	COG3655	Transcriptional regulator
CR541_RS01610	COG2217	Heavy metal translocating P-type atpase
CR541_RS01635	COG4475	Protein of unknown function (DUF436)
CR541_RS01665	COG4221	oxidoreductase activity
CR541_RS01670	COG1902	pentaerythritol trinitrate reductase activity
CR541_RS01670	COG0446	pyridine nucleotide-disulphide oxidoreductase
CR541_RS01675	COG1959	2 iron, 2 sulfur cluster binding
CR541_RS01710	COG0544	peptidyl-prolyl cis-trans isomerase activity
CR541_RS01730	COG3343	RNA polymerase activity
CR541_RS01735	COG0504	CTP synthase activity
CR541_RS01745	COG0191	fructose-bisphosphate aldolase activity
CR541_RS01750	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CR541_RS01785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CR541_RS01790	COG0252	asparaginase activity
CR541_RS01805	COG0589	response to stress
CR541_RS01810	COG0436	Aminotransferase
CR541_RS01815	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CR541_RS01820	COG1335	isochorismatase
CR541_RS01825	COG0335	large ribosomal subunit rRNA binding
CR541_RS01835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CR541_RS01840	COG0154	amidase activity
CR541_RS01845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CR541_RS01850	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CR541_RS01855	COG1609	Transcriptional regulator
CR541_RS01860	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CR541_RS01865	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CR541_RS01875	COG3142	Participates in the control of copper homeostasis
CR541_RS01890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CR541_RS01900	COG1534	Rna-binding protein
CR541_RS01905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CR541_RS01910	COG1713	HD superfamily hydrolase involved in NAD metabolism
CR541_RS01935	COG0799	negative regulation of ribosome biogenesis
CR541_RS01940	COG2226	methyltransferase
CR541_RS01945	COG5290	Psort location Cytoplasmic, score
CR541_RS01955	COG0789	Transcriptional regulator
CR541_RS01960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CR541_RS01980	COG0242	peptide deformylase activity
CR541_RS01990	COG1640	4-alpha-glucanotransferase
CR541_RS01995	COG0058	SHG alpha-glucan phosphorylase activity
CR541_RS02010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR541_RS02010	COG1263	PTS System
CR541_RS02010	COG2190	(PTS) system
CR541_RS02025	COG0217	transcriptional regulatory protein
CR541_RS02035	COG4720	Psort location CytoplasmicMembrane, score
CR541_RS02045	COG1054	Belongs to the UPF0176 family
CR541_RS02055	COG1122	ATPase activity
CR541_RS02070	COG0357	Ribosomal RNA small subunit methyltransferase G
CR541_RS02075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR541_RS02080	COG3331	DNA recombination
CR541_RS02085	COG4474	Belongs to the UPF0398 family
CR541_RS02090	COG3599	regulation of cell shape
CR541_RS02100	COG0116	Belongs to the methyltransferase superfamily
CR541_RS02110	COG1854	S-ribosylhomocysteine lyase activity
CR541_RS02115	COG1418	mRNA catabolic process
CR541_RS02125	COG1758	RNA polymerase activity
CR541_RS02130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CR541_RS02135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CR541_RS02140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CR541_RS02140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CR541_RS02145	COG0631	protein serine/threonine phosphatase activity
CR541_RS02150	COG0515	serine threonine protein kinase
CR541_RS02150	COG2815	serine threonine protein kinase
CR541_RS02175	COG1098	S1 RNA binding domain
CR541_RS02185	COG1739	Uncharacterized protein family UPF0029
CR541_RS02190	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CR541_RS02270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CR541_RS02275	COG2137	regulation of response to DNA damage stimulus
CR541_RS02280	COG3557	Belongs to the UPF0374 family
CR541_RS02290	COG2188	Transcriptional regulator
CR541_RS02295	COG2188	Transcriptional regulator
CR541_RS02305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR541_RS02315	COG3716	PTS system mannose fructose sorbose family IID component
CR541_RS02325	COG2017	converts alpha-aldose to the beta-anomer
CR541_RS02340	COG0346	lactoylglutathione lyase activity
CR541_RS02390	COG1217	gtp-binding protein TYPA
CR541_RS02405	COG0681	Belongs to the peptidase S26 family
CR541_RS02440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CR541_RS02455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CR541_RS02460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CR541_RS02465	COG1799	cell septum assembly
CR541_RS02480	COG3599	regulation of cell shape
CR541_RS02500	COG0494	nUDIX hydrolase
CR541_RS02500	COG0406	alpha-ribazole phosphatase activity
CR541_RS02505	COG0542	response to heat
CR541_RS02510	COG4703	Protein of unknown function (DUF1797)
CR541_RS02515	COG0765	amino acid transport
CR541_RS02525	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CR541_RS02565	COG0789	Transcriptional regulator
CR541_RS02580	COG0826	peptidase U32
CR541_RS02595	COG4443	Transcriptional Coactivator p15 (PC4)
CR541_RS02600	COG1268	BioY protein
CR541_RS02605	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CR541_RS02610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CR541_RS02615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CR541_RS02620	COG1136	(ABC) transporter
CR541_RS02625	COG0577	efflux transmembrane transporter activity
CR541_RS02640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CR541_RS02650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CR541_RS02660	COG3859	Proton-coupled thiamine transporter YuaJ
CR541_RS02680	COG0772	Belongs to the SEDS family
CR541_RS02685	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CR541_RS02690	COG1595	DNA-templated transcription, initiation
CR541_RS02700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CR541_RS02705	COG0149	triose-phosphate isomerase activity
CR541_RS02715	COG1078	dGTPase activity
CR541_RS02730	COG2826	transposase and inactivated derivatives, IS30 family
CR541_RS02735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CR541_RS02745	COG1131	(ABC) transporter
CR541_RS02750	COG2188	Transcriptional regulator
CR541_RS02760	COG0205	6-phosphofructokinase activity
CR541_RS02765	COG0469	pyruvate kinase activity
CR541_RS02775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CR541_RS02780	COG2755	lipolytic protein G-D-S-L family
CR541_RS02780	COG0657	acetylesterase activity
CR541_RS02790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CR541_RS02795	COG0765	amino acid transport
CR541_RS02800	COG1126	abc transporter atp-binding protein
CR541_RS02805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR541_RS02825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CR541_RS02830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CR541_RS02835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CR541_RS02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CR541_RS02855	COG3022	response to hydroperoxide
CR541_RS02865	COG3944	biosynthesis protein
CR541_RS02875	COG4464	protein tyrosine phosphatase activity
CR541_RS02905	COG1216	Glycosyl transferase, family 2
CR541_RS02905	COG1442	glycosyl transferase family 8
CR541_RS02910	COG1442	glycosyl transferase family 8
CR541_RS02910	COG1216	Glycosyl transferase, family 2
CR541_RS02945	COG2089	acid synthase
CR541_RS02960	COG1083	cytidylyl-transferase
CR541_RS02960	COG2755	lipolytic protein G-D-S-L family
CR541_RS03035	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CR541_RS03040	COG0077	Prephenate dehydratase
CR541_RS03050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CR541_RS03065	COG0488	(ABC) transporter
CR541_RS03080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CR541_RS03105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR541_RS03105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR541_RS03150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CR541_RS03175	COG0270	DNA (cytosine-5-)-methyltransferase activity
CR541_RS03220	COG4695	Portal protein
CR541_RS03225	COG0740	serine-type endopeptidase activity
CR541_RS03295	COG0860	N-Acetylmuramoyl-L-alanine amidase
CR541_RS03295	COG1388	LysM domain
CR541_RS03355	COG0456	acetyltransferase
CR541_RS03400	COG0270	DNA (cytosine-5-)-methyltransferase activity
CR541_RS03555	COG1475	DNA binding
CR541_RS03560	COG4443	Transcriptional Coactivator p15 (PC4)
CR541_RS03615	COG1396	sequence-specific DNA binding
CR541_RS03620	COG0542	response to heat
CR541_RS03625	COG0613	PHP domain protein
CR541_RS03645	COG3843	relaxase mobilization nuclease domain protein
CR541_RS03670	COG1131	(ABC) transporter
CR541_RS03725	COG0562	UDP-galactopyranose mutase
CR541_RS03730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CR541_RS03750	COG0436	Aminotransferase
CR541_RS03760	COG0017	Asparaginyl-tRNA synthetase
CR541_RS03780	COG0534	Mate efflux family protein
CR541_RS03785	COG0251	oxidation-reduction process
CR541_RS03790	COG1660	Displays ATPase and GTPase activities
CR541_RS03795	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CR541_RS03800	COG1481	regulation of sporulation
CR541_RS03815	COG0454	-acetyltransferase
CR541_RS03820	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CR541_RS03825	COG0549	Belongs to the carbamate kinase family
CR541_RS03830	COG1288	antiporter activity
CR541_RS03835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CR541_RS03840	COG3583	domain protein
CR541_RS03840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CR541_RS03840	COG3064	Membrane
CR541_RS03845	COG1438	arginine binding
CR541_RS03850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CR541_RS03855	COG0363	glucosamine-6-phosphate deaminase activity
CR541_RS03885	COG1696	Membrane protein involved in D-alanine export
CR541_RS03890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CR541_RS03895	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CR541_RS03905	COG0435	Glutathione S-transferase
CR541_RS03910	COG1187	pseudouridine synthase activity
CR541_RS03915	COG0386	Belongs to the glutathione peroxidase family
CR541_RS03920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CR541_RS03925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CR541_RS03930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CR541_RS03935	COG1120	ATPase activity
CR541_RS03940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CR541_RS03945	COG0204	Acyl-transferase
CR541_RS03950	COG1555	photosystem II stabilization
CR541_RS03950	COG1596	polysaccharide export
CR541_RS03955	COG2333	competence protein COMEC
CR541_RS03955	COG0658	competence protein
CR541_RS03960	COG0517	IMP dehydrogenase activity
CR541_RS03975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR541_RS03980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CR541_RS03985	COG0470	DNA polymerase III
CR541_RS03990	COG4467	Involved in initiation control of chromosome replication
CR541_RS04000	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CR541_RS04010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CR541_RS04015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CR541_RS04020	COG1393	Belongs to the ArsC family
CR541_RS04030	COG0708	Exodeoxyribonuclease III
CR541_RS04040	COG0531	amino acid
CR541_RS04110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CR541_RS04115	COG4684	Psort location CytoplasmicMembrane, score
CR541_RS04120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CR541_RS04130	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CR541_RS04140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CR541_RS04145	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CR541_RS04155	COG0732	type I restriction modification DNA specificity domain
CR541_RS04190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CR541_RS04195	COG1349	DNA-binding transcription factor activity
CR541_RS04205	COG1447	Phosphotransferase system cellobiose-specific component IIA
CR541_RS04210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR541_RS04215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR541_RS04220	COG1882	Formate acetyltransferase
CR541_RS04240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CR541_RS04245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CR541_RS04250	COG0446	pyridine nucleotide-disulphide oxidoreductase
CR541_RS04260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CR541_RS04265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CR541_RS04270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CR541_RS04275	COG0346	lactoylglutathione lyase activity
CR541_RS04285	COG1164	Oligoendopeptidase f
CR541_RS04300	COG0210	DNA helicase
CR541_RS04315	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CR541_RS04330	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CR541_RS04345	COG1122	ATPase activity
CR541_RS04350	COG1122	ATPase activity
CR541_RS04355	COG1011	Hydrolase
CR541_RS04385	COG1131	(ABC) transporter
CR541_RS04415	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CR541_RS04420	COG1074	ATP-dependent DNA helicase activity
CR541_RS04430	COG0187	DNA topoisomerase II activity
CR541_RS04455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CR541_RS04465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CR541_RS04485	COG0539	negative regulation of cytoplasmic translation
CR541_RS04510	COG1104	cysteine desulfurase activity
CR541_RS04515	COG0301	tRNA thio-modification
CR541_RS04520	COG1114	Component of the transport system for branched-chain amino acids
CR541_RS04525	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CR541_RS04530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CR541_RS04550	COG0564	pseudouridine synthase activity
CR541_RS04565	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CR541_RS04570	COG0540	Belongs to the ATCase OTCase family
CR541_RS04575	COG0505	Belongs to the CarA family
CR541_RS04585	COG2521	methyltransferase
CR541_RS04585	COG2136	Putative SAM-dependent methyltransferase
CR541_RS04590	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CR541_RS04600	COG0228	four-way junction DNA binding
CR541_RS04615	COG1132	(ABC) transporter
CR541_RS04620	COG0726	polysaccharide deacetylase
CR541_RS04625	COG0460	homoserine dehydrogenase
CR541_RS04630	COG0083	homoserine kinase activity
CR541_RS04635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CR541_RS04640	COG3842	ATPase activity
CR541_RS04645	COG1176	ABC-type spermidine putrescine transport system, permease component I
CR541_RS04650	COG1177	transmembrane transport
CR541_RS04660	COG0038	chloride channel
CR541_RS04675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CR541_RS04680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CR541_RS04695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CR541_RS04700	COG0336	Belongs to the RNA methyltransferase TrmD family
CR541_RS04705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CR541_RS04710	COG1349	DNA-binding transcription factor activity
CR541_RS04715	COG1105	Belongs to the carbohydrate kinase PfkB family
CR541_RS04720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR541_RS04720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR541_RS04720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR541_RS04730	COG1307	EDD domain protein, DegV family
CR541_RS04735	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CR541_RS04740	COG0617	tRNA 3'-terminal CCA addition
CR541_RS04745	COG0488	(ABC) transporter
CR541_RS04755	COG1940	carbohydrate kinase activity
CR541_RS04770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CR541_RS04775	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CR541_RS04785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CR541_RS04805	COG0481	GTPase activity
CR541_RS04830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CR541_RS04835	COG2890	protein-(glutamine-N5) methyltransferase activity
CR541_RS04840	COG0009	L-threonylcarbamoyladenylate synthase
CR541_RS04850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CR541_RS04860	COG0741	lytic transglycosylase activity
CR541_RS04865	COG4221	oxidoreductase activity
CR541_RS04890	COG1401	restriction endodeoxyribonuclease activity
CR541_RS04895	COG4268	DNA restriction-modification system
CR541_RS04905	COG2188	Transcriptional regulator
CR541_RS04910	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CR541_RS04915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CR541_RS04930	COG1660	Displays ATPase and GTPase activities
CR541_RS04950	COG4974	Belongs to the 'phage' integrase family
CR541_RS04965	COG0745	RESPONSE REGULATOR receiver
CR541_RS04985	COG1136	(ABC) transporter
CR541_RS05025	COG2382	esterase
CR541_RS05035	COG3708	Transcriptional regulator
CR541_RS05035	COG2207	Transcriptional regulator
CR541_RS05040	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CR541_RS05045	COG0647	UMP catabolic process
CR541_RS05050	COG0222	ribosome binding
CR541_RS05055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CR541_RS05060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CR541_RS05065	COG0758	DNA mediated transformation
CR541_RS05070	COG0110	maltose O-acetyltransferase activity
CR541_RS05075	COG1937	Protein conserved in bacteria
CR541_RS05085	COG0446	pyridine nucleotide-disulphide oxidoreductase
CR541_RS05095	COG1272	protein, Hemolysin III
CR541_RS05105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CR541_RS05110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CR541_RS05125	COG0737	Belongs to the 5'-nucleotidase family
CR541_RS05135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CR541_RS05140	COG0463	Glycosyl transferase, family 2
CR541_RS05150	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CR541_RS05155	COG0284	orotidine-5'-phosphate decarboxylase activity
CR541_RS05160	COG0167	dihydroorotate dehydrogenase activity
CR541_RS05185	COG0297	glycogen (starch) synthase activity
CR541_RS05195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR541_RS05200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR541_RS05240	COG1126	abc transporter atp-binding protein
CR541_RS05250	COG0488	(ABC) transporter
CR541_RS05255	COG2873	o-acetylhomoserine
CR541_RS05280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR541_RS05280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR541_RS05290	COG3711	transcriptional antiterminator
CR541_RS05295	COG3684	Belongs to the aldolase LacD family
CR541_RS05305	COG0698	ribose 5-phosphate isomerase
CR541_RS05310	COG0698	ribose 5-phosphate isomerase
CR541_RS05320	COG1349	DNA-binding transcription factor activity
CR541_RS05350	COG1396	sequence-specific DNA binding
CR541_RS05355	COG1194	a g-specific adenine glycosylase
CR541_RS05365	COG1132	(ABC) transporter
CR541_RS05370	COG1132	(ABC) transporter
CR541_RS05375	COG0280	phosphate acetyltransferase
CR541_RS05380	COG0564	pseudouridine synthase activity
CR541_RS05385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CR541_RS05390	COG2357	RelA SpoT domain protein
CR541_RS05395	COG4116	CYTH
CR541_RS05405	COG1104	cysteine desulfurase activity
CR541_RS05420	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CR541_RS05425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CR541_RS05435	COG3764	Sortase (surface protein transpeptidase)
CR541_RS05440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CR541_RS05445	COG0039	L-malate dehydrogenase activity
CR541_RS05455	COG1079	Belongs to the binding-protein-dependent transport system permease family
CR541_RS05460	COG4603	Belongs to the binding-protein-dependent transport system permease family
CR541_RS05465	COG3845	ABC transporter
CR541_RS05470	COG1744	ABC transporter substrate-binding protein PnrA-like
CR541_RS05485	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CR541_RS05490	COG2813	Specifically methylates the guanine in position
CR541_RS05495	COG1072	(Pantothenic acid kinase))
CR541_RS05525	COG5002	protein histidine kinase activity
CR541_RS05530	COG0745	RESPONSE REGULATOR receiver
CR541_RS05545	COG0704	Plays a role in the regulation of phosphate uptake
CR541_RS05550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CR541_RS05555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CR541_RS05560	COG0581	inorganic phosphate transmembrane transporter activity
CR541_RS05565	COG0573	inorganic phosphate transmembrane transporter activity
CR541_RS05575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CR541_RS05575	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CR541_RS05580	COG0483	inositol monophosphate 1-phosphatase activity
CR541_RS05585	COG4476	Belongs to the UPF0223 family
CR541_RS05590	COG1393	Belongs to the ArsC family
CR541_RS05595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CR541_RS05600	COG0196	riboflavin kinase activity
CR541_RS05605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CR541_RS05665	COG0561	phosphatase activity
CR541_RS05670	COG2195	Cleaves the N-terminal amino acid of tripeptides
CR541_RS05705	COG3759	membrane
CR541_RS05710	COG1846	Transcriptional regulator
CR541_RS05725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CR541_RS05730	COG2610	gluconate transmembrane transporter activity
CR541_RS05750	COG0302	gtp cyclohydrolase
CR541_RS05755	COG1051	belongs to the nudix hydrolase family
CR541_RS05780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR541_RS05780	COG0072	phenylalanine-tRNA ligase activity
CR541_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
CR541_RS05815	COG1312	Catalyzes the dehydration of D-mannonate
CR541_RS05825	COG0800	Aldolase
CR541_RS05835	COG3250	beta-galactosidase activity
CR541_RS05845	COG2211	Major facilitator Superfamily
CR541_RS05860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CR541_RS05870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CR541_RS05875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CR541_RS05880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CR541_RS05885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CR541_RS05890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CR541_RS05895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CR541_RS05900	COG0356	it plays a direct role in the translocation of protons across the membrane
CR541_RS05910	COG1597	lipid kinase activity
CR541_RS05920	COG0701	Predicted permease
CR541_RS05925	COG3689	TIGRFAM TIGR03943 family protein
CR541_RS05930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CR541_RS05945	COG0552	protein localization to endoplasmic reticulum
CR541_RS05950	COG0561	phosphatase activity
CR541_RS05955	COG0561	phosphatase activity
CR541_RS05960	COG1196	nuclear chromosome segregation
CR541_RS05985	COG2826	transposase and inactivated derivatives, IS30 family
CR541_RS06000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR541_RS06005	COG0538	isocitrate dehydrogenase activity
CR541_RS06010	COG0372	Belongs to the citrate synthase family
CR541_RS06015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CR541_RS06020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CR541_RS06025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR541_RS06035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR541_RS06040	COG1609	Transcriptional regulator
CR541_RS06055	COG5492	domain, Protein
CR541_RS06060	COG5492	domain, Protein
CR541_RS06065	COG5492	domain, Protein
CR541_RS06075	COG3716	PTS system mannose fructose sorbose family IID component
CR541_RS06085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR541_RS06090	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CR541_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
CR541_RS06155	COG1476	TRANSCRIPTIONal
CR541_RS06180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CR541_RS06190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CR541_RS06195	COG4122	O-methyltransferase activity
CR541_RS06220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR541_RS06220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR541_RS06235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CR541_RS06240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CR541_RS06245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CR541_RS06250	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CR541_RS06260	COG1116	anion transmembrane transporter activity
CR541_RS06260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CR541_RS06265	COG4120	Belongs to the binding-protein-dependent transport system permease family
CR541_RS06285	COG3684	Belongs to the aldolase LacD family
CR541_RS06295	COG3679	Belongs to the UPF0342 family
CR541_RS06300	COG0287	Prephenate dehydrogenase
CR541_RS06305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CR541_RS06310	COG0710	3-dehydroquinate dehydratase activity
CR541_RS06315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CR541_RS06320	COG1368	sulfuric ester hydrolase activity
CR541_RS06335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CR541_RS06345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CR541_RS06375	COG1216	Glycosyl transferase, family 2
CR541_RS06390	COG1442	glycosyl transferase family 8
CR541_RS06390	COG1216	Glycosyl transferase, family 2
CR541_RS06395	COG1442	glycosyl transferase family 8
CR541_RS06425	COG0463	Glycosyl transferase, family 2
CR541_RS06455	COG1091	dTDP-4-dehydrorhamnose reductase activity
CR541_RS06460	COG1088	dTDP-glucose 4,6-dehydratase activity
CR541_RS06475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CR541_RS06485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CR541_RS06490	COG2384	SAM-dependent methyltransferase
CR541_RS06505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CR541_RS06525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CR541_RS06525	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CR541_RS06530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CR541_RS06540	COG0300	oxidoreductase activity
CR541_RS06545	COG1234	tRNA 3'-trailer cleavage
CR541_RS06555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CR541_RS06560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CR541_RS06570	COG2807	transmembrane transport
CR541_RS06575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CR541_RS06580	COG1702	phosphate starvation-inducible protein PhoH
CR541_RS06585	COG4479	Belongs to the UPF0346 family
CR541_RS06600	COG2996	Protein conserved in bacteria
CR541_RS06605	COG0233	cytoplasmic translational termination
CR541_RS06610	COG0528	UMP kinase activity
CR541_RS06615	COG2244	polysaccharide biosynthetic process
CR541_RS06620	COG0625	glutathione transferase activity
CR541_RS06645	COG0346	lactoylglutathione lyase activity
CR541_RS06650	COG1674	ftsk spoiiie
CR541_RS06650	COG0697	spore germination
CR541_RS06655	COG1621	beta-fructofuranosidase activity
CR541_RS06665	COG0395	ABC-type sugar transport system, permease component
CR541_RS06670	COG4209	transmembrane transport
CR541_RS06675	COG1609	Transcriptional regulator
CR541_RS06695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CR541_RS06710	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CR541_RS06720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CR541_RS06730	COG1181	Belongs to the D-alanine--D-alanine ligase family
CR541_RS06735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CR541_RS06740	COG0768	penicillin binding
CR541_RS06750	COG0488	(ABC) transporter
CR541_RS06760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CR541_RS06770	COG0745	RESPONSE REGULATOR receiver
CR541_RS06775	COG1126	abc transporter atp-binding protein
CR541_RS06780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR541_RS06785	COG0765	amino acid transport
CR541_RS06790	COG0765	amino acid transport
CR541_RS06795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CR541_RS06810	COG0438	transferase activity, transferring glycosyl groups
CR541_RS06830	COG1609	Transcriptional regulator
CR541_RS06845	COG3716	PTS system mannose fructose sorbose family IID component
CR541_RS06850	COG3715	PTS system
CR541_RS06855	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR541_RS06870	COG1070	Carbohydrate kinase
CR541_RS06875	COG2115	Belongs to the xylose isomerase family
CR541_RS06880	COG1940	carbohydrate kinase activity
CR541_RS06900	COG0343	queuine tRNA-ribosyltransferase activity
CR541_RS06915	COG1832	CoA-binding protein
CR541_RS06925	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR541_RS06925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR541_RS06940	COG1136	(ABC) transporter
CR541_RS06955	COG2217	Heavy metal translocating P-type atpase
CR541_RS06970	COG1063	alcohol dehydrogenase
CR541_RS06975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CR541_RS06980	COG0557	exoribonuclease II activity
CR541_RS06985	COG0017	Asparaginyl-tRNA synthetase
CR541_RS06995	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CR541_RS07000	COG2814	Major facilitator Superfamily
CR541_RS07010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CR541_RS07015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CR541_RS07020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CR541_RS07030	COG1737	Transcriptional regulator
CR541_RS07040	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CR541_RS07050	COG1011	Hydrolase
CR541_RS07055	COG1132	(ABC) transporter
CR541_RS07060	COG1132	(ABC) transporter
CR541_RS07090	COG2177	Part of the ABC transporter FtsEX involved in
CR541_RS07095	COG2884	Cell division ATP-binding protein ftsE
CR541_RS07105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CR541_RS07135	COG2826	transposase and inactivated derivatives, IS30 family
CR541_RS07170	COG2151	metal-sulfur cluster biosynthetic enzyme
CR541_RS07175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CR541_RS07180	COG0358	DNA primase activity
CR541_RS07185	COG1970	mechanosensitive ion channel activity
CR541_RS07190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CR541_RS07195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CR541_RS07205	COG0647	UMP catabolic process
CR541_RS07210	COG1051	belongs to the nudix hydrolase family
CR541_RS07220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CR541_RS07230	COG0058	SHG alpha-glucan phosphorylase activity
CR541_RS07235	COG0813	purine-nucleoside phosphorylase activity
CR541_RS07240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CR541_RS07250	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CR541_RS07255	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CR541_RS07260	COG0732	type I restriction modification DNA specificity domain
CR541_RS07280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CR541_RS07295	COG2268	Band 7 protein
CR541_RS07300	COG1704	LemA family
CR541_RS07310	COG1573	uracil-dna glycosylase
CR541_RS07345	COG2226	methyltransferase
CR541_RS07350	COG0488	(ABC) transporter
CR541_RS07355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CR541_RS07370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CR541_RS07375	COG3442	glutamine amidotransferase
CR541_RS07385	COG2226	methyltransferase
CR541_RS07400	COG0488	(ABC) transporter
CR541_RS07440	COG3842	ATPase activity
CR541_RS07460	COG1263	PTS System
CR541_RS07460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR541_RS07460	COG2190	(PTS) system
CR541_RS07465	COG3711	transcriptional antiterminator
CR541_RS07470	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CR541_RS07475	COG3527	Alpha-acetolactate decarboxylase
CR541_RS07485	COG0628	permease
CR541_RS07490	COG2706	6-phosphogluconolactonase activity
CR541_RS07500	COG1011	Hydrolase
CR541_RS07545	COG0560	Phosphoserine phosphatase
CR541_RS07550	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CR541_RS07555	COG0187	DNA topoisomerase II activity
CR541_RS07560	COG0693	protein deglycase activity
CR541_RS07565	COG0772	Belongs to the SEDS family
CR541_RS07570	COG0582	viral genome integration into host DNA
CR541_RS07655	COG0582	viral genome integration into host DNA
CR541_RS07670	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CR541_RS07675	COG0716	FMN binding
CR541_RS07685	COG1605	Chorismate mutase
CR541_RS07685	COG0287	Prephenate dehydrogenase
CR541_RS07690	COG0038	chloride channel
CR541_RS07700	COG0737	Belongs to the 5'-nucleotidase family
CR541_RS07705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CR541_RS07710	COG1466	dna polymerase III delta subunit
CR541_RS07745	COG0683	leucine binding
CR541_RS07760	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CR541_RS07765	COG0366	Alpha amylase catalytic
CR541_RS07775	COG0395	ABC-type sugar transport system, permease component
CR541_RS07780	COG1175	transmembrane transport
CR541_RS07785	COG1653	transport
CR541_RS07795	COG2207	Transcriptional regulator
CR541_RS07800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CR541_RS07805	COG0626	cystathionine gamma-synthase activity
CR541_RS07825	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CR541_RS07830	COG2827	Endonuclease containing a URI domain
CR541_RS07855	COG0640	Transcriptional regulator
CR541_RS07860	COG0513	Belongs to the DEAD box helicase family
CR541_RS07870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR541_RS07910	COG0494	nUDIX hydrolase
CR541_RS07915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CR541_RS07930	COG1028	Short-chain dehydrogenase reductase Sdr
CR541_RS07965	COG0577	efflux transmembrane transporter activity
CR541_RS07970	COG1136	(ABC) transporter
CR541_RS07975	COG2205	protein histidine kinase activity
CR541_RS07990	COG0436	Aminotransferase
CR541_RS08000	COG1174	glycine betaine transport
CR541_RS08005	COG0517	IMP dehydrogenase activity
CR541_RS08005	COG1125	glycine betaine transport
CR541_RS08025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CR541_RS08030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CR541_RS08035	COG1482	cell wall glycoprotein biosynthetic process
CR541_RS08060	COG3091	SprT-like family
CR541_RS08065	COG2183	response to ionizing radiation
CR541_RS08070	COG0656	L-ascorbic acid biosynthetic process
CR541_RS08075	COG4708	membrane
CR541_RS08080	COG2246	polysaccharide biosynthetic process
CR541_RS08090	COG0024	Methionine aminopeptidase
CR541_RS08100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CR541_RS08105	COG2249	NAD(P)H dehydrogenase (quinone) activity
CR541_RS08110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CR541_RS08115	COG2131	deaminase
CR541_RS08125	COG1363	Peptidase, m42
CR541_RS08140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CR541_RS08145	COG1956	GAF domain-containing protein
CR541_RS08155	COG1695	Transcriptional regulator
CR541_RS08170	COG0513	Belongs to the DEAD box helicase family
CR541_RS08175	COG0726	polysaccharide deacetylase
CR541_RS08200	COG0183	Belongs to the thiolase family
CR541_RS08205	COG3425	synthase
CR541_RS08235	COG0776	regulation of translation
CR541_RS08245	COG2755	lipolytic protein G-D-S-L family
CR541_RS08250	COG1307	EDD domain protein, DegV family
CR541_RS08255	COG0497	DNA recombination
CR541_RS08260	COG1438	arginine binding
CR541_RS08265	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CR541_RS08275	COG1722	exodeoxyribonuclease VII activity
CR541_RS08280	COG1570	exodeoxyribonuclease VII activity
CR541_RS08285	COG2321	neutral zinc metallopeptidase
CR541_RS08290	COG1755	Isoprenylcysteine carboxyl methyltransferase
CR541_RS08295	COG5002	protein histidine kinase activity
CR541_RS08300	COG0745	RESPONSE REGULATOR receiver
CR541_RS08325	COG1227	inorganic diphosphatase activity
CR541_RS08335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CR541_RS08340	COG1253	flavin adenine dinucleotide binding
CR541_RS08345	COG1119	ATPase activity
CR541_RS08350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CR541_RS08360	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CR541_RS08365	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CR541_RS08380	COG4470	Protein conserved in bacteria
CR541_RS08385	COG3480	Lon protease (S16) C-terminal proteolytic domain
CR541_RS08390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CR541_RS08395	COG0742	ribosomal rna small subunit methyltransferase
CR541_RS08405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CR541_RS08410	COG4483	Protein conserved in bacteria
CR541_RS08415	COG2197	response regulator
CR541_RS08420	COG2203	Gaf domain
CR541_RS08420	COG4585	Histidine kinase
CR541_RS08425	COG0842	Transport permease protein
CR541_RS08430	COG1131	(ABC) transporter
CR541_RS08445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CR541_RS08460	COG0671	phosphoesterase, PA-phosphatase related
CR541_RS08465	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CR541_RS08480	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CR541_RS08485	COG1187	pseudouridine synthase activity
CR541_RS08490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CR541_RS08495	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CR541_RS08500	COG0582	viral genome integration into host DNA
CR541_RS08520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CR541_RS08525	COG3763	UPF0154 protein
CR541_RS08535	COG3579	cysteine-type endopeptidase activity
CR541_RS08550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CR541_RS08555	COG1254	Belongs to the acylphosphatase family
CR541_RS08565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CR541_RS08570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CR541_RS08580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CR541_RS08590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CR541_RS08605	COG1160	GTP binding
CR541_RS08615	COG0778	Nitroreductase
CR541_RS08620	COG1484	DNA-dependent DNA replication
CR541_RS08630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CR541_RS08635	COG0628	permease
CR541_RS08640	COG0745	RESPONSE REGULATOR receiver
CR541_RS08645	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CR541_RS08655	COG0492	ferredoxin-NADP+ reductase activity
CR541_RS08665	COG0513	Belongs to the DEAD box helicase family
CR541_RS08675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CR541_RS08680	COG0768	penicillin binding
CR541_RS08690	COG0275	rRNA processing
CR541_RS08745	COG4939	FMN-binding domain protein
CR541_RS08750	COG0142	geranyltranstransferase activity
CR541_RS08755	COG1252	NADH dehydrogenase
CR541_RS08770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CR541_RS08775	COG0569	domain protein
CR541_RS08780	COG0534	Mate efflux family protein
CR541_RS08790	COG4224	UPF0291 protein
CR541_RS08795	COG0751	glycine-tRNA ligase activity
CR541_RS08820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CR541_RS08825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CR541_RS08830	COG1464	Belongs to the NlpA lipoprotein family
CR541_RS08835	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CR541_RS08840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CR541_RS08845	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CR541_RS08850	COG2252	PERMEase
CR541_RS08855	COG0561	phosphatase activity
CR541_RS08865	COG3715	PTS system
CR541_RS08870	COG3716	PTS system mannose fructose sorbose family IID component
CR541_RS08895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CR541_RS08940	COG0439	Biotin carboxylase
CR541_RS08960	COG1028	Short-chain dehydrogenase reductase Sdr
CR541_RS08965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CR541_RS08970	COG2070	2-Nitropropane dioxygenase
CR541_RS08980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CR541_RS08990	COG1024	Enoyl-CoA hydratase
CR541_RS08995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CR541_RS09000	COG0527	aspartate kinase activity
CR541_RS09015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CR541_RS09020	COG0736	holo-[acyl-carrier-protein] synthase activity
CR541_RS09025	COG0653	protein targeting
CR541_RS09035	COG1940	carbohydrate kinase activity
CR541_RS09040	COG1263	PTS System
CR541_RS09040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR541_RS09040	COG2190	(PTS) system
CR541_RS09045	COG1621	beta-fructofuranosidase activity
CR541_RS09050	COG1609	Transcriptional regulator
CR541_RS09055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CR541_RS09070	COG0006	proline dipeptidase activity
CR541_RS09075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CR541_RS09090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CR541_RS09095	COG0629	single-stranded DNA binding
CR541_RS09105	COG2826	transposase and inactivated derivatives, IS30 family
CR541_RS09110	COG0095	Lipoate-protein ligase
CR541_RS09125	COG0508	dehydrogenase complex catalyzes the overall conversion of
CR541_RS09130	COG0022	dehydrogenase e1 component
CR541_RS09130	COG0508	dehydrogenase complex catalyzes the overall conversion of
CR541_RS09135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CR541_RS09155	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CR541_RS09160	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CR541_RS09170	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CR541_RS09175	COG0195	Participates in both transcription termination and antitermination
CR541_RS09190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CR541_RS09200	COG4473	ABC transporter
CR541_RS09205	COG1131	(ABC) transporter
CR541_RS09210	COG0537	adenosine 5'-monophosphoramidase activity
CR541_RS09220	COG1316	TRANSCRIPTIONal
CR541_RS09230	COG0802	atpase or kinase
CR541_RS09235	COG1461	Dihydroxyacetone kinase
CR541_RS09250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CR541_RS09255	COG0601	transmembrane transport
CR541_RS09260	COG4608	Belongs to the ABC transporter superfamily
CR541_RS09275	COG1686	Belongs to the peptidase S11 family
CR541_RS09290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CR541_RS09295	COG0719	Fe-S assembly protein
CR541_RS09305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CR541_RS09310	COG4862	establishment of competence for transformation
CR541_RS09315	COG1968	undecaprenyl-diphosphatase activity
CR541_RS09320	COG0765	amino acid transport
CR541_RS09340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CR541_RS09345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CR541_RS09350	COG0440	acetolactate synthase activity
CR541_RS09355	COG0028	Belongs to the TPP enzyme family
CR541_RS09375	COG0129	dihydroxy-acid dehydratase activity
CR541_RS09385	COG2151	metal-sulfur cluster biosynthetic enzyme
CR541_RS09400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CR541_RS09420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CR541_RS09445	COG3842	ATPase activity
CR541_RS09455	COG4753	response regulator
CR541_RS09455	COG2207	Transcriptional regulator
CR541_RS09460	COG2972	Histidine kinase
CR541_RS09480	COG1653	transport
CR541_RS09485	COG0395	ABC-type sugar transport system, permease component
CR541_RS09490	COG1175	transmembrane transport
CR541_RS09505	COG0383	alpha-mannosidase activity
CR541_RS09525	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CR541_RS09545	COG1045	serine acetyltransferase
CR541_RS09550	COG1185	polyribonucleotide nucleotidyltransferase activity
CR541_RS09575	COG1263	PTS System
CR541_RS09575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR541_RS09585	COG1737	Transcriptional regulator
CR541_RS09590	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CR541_RS09610	COG1187	pseudouridine synthase activity
CR541_RS09630	COG0242	peptide deformylase activity
CR541_RS09640	COG0066	3-isopropylmalate dehydratase activity
CR541_RS09665	COG2309	aminopeptidase activity
CR541_RS09685	COG2176	DNA-directed DNA polymerase activity
CR541_RS09690	COG2376	Dihydroxyacetone kinase
CR541_RS09700	COG2376	Dihydroxyacetone kinase
CR541_RS09705	COG1461	Dihydroxyacetone kinase
CR541_RS09710	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CR541_RS09715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CR541_RS09720	COG0442	prolyl-tRNA aminoacylation
CR541_RS09730	COG4589	Belongs to the CDS family
CR541_RS09735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CR541_RS09740	COG1862	Preprotein translocase
CR541_RS09750	COG2918	glutathione biosynthetic process
CR541_RS09750	COG1181	Belongs to the D-alanine--D-alanine ligase family
CR541_RS09760	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CR541_RS09765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CR541_RS09780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CR541_RS09790	COG4463	regulation of RNA biosynthetic process
CR541_RS09805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CR541_RS09840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CR541_RS09845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR541_RS09850	COG0492	ferredoxin-NADP+ reductase activity
CR541_RS09855	COG0564	pseudouridine synthase activity
CR541_RS09860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CR541_RS09880	COG1564	THIamine pyrophosphokinase
CR541_RS09890	COG1162	GTPase activity
CR541_RS09940	COG4115	mRNA cleavage
CR541_RS09975	COG0084	hydrolase, TatD family'
CR541_RS09985	COG1847	R3H domain protein
CR541_RS09995	COG0594	ribonuclease P activity
CR541_RS10000	COG0165	Argininosuccinate lyase
CR541_RS10005	COG0137	argininosuccinate synthase activity
CR541_RS10015	COG1827	regulation of RNA biosynthetic process
CR541_RS10030	COG2040	homocysteine
CR541_RS10035	COG0833	amino acid
CR541_RS10080	COG0756	dUTP diphosphatase activity
CR541_RS10085	COG1132	(ABC) transporter
CR541_RS10090	COG1132	(ABC) transporter
CR541_RS10100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CR541_RS10105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CR541_RS10110	COG0705	Rhomboid family
CR541_RS10115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CR541_RS10120	COG1473	amidohydrolase
CR541_RS10125	COG2171	N-acyltransferase activity
CR541_RS10140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CR541_RS10165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CR541_RS10190	COG3623	hexulose-6-phosphate isomerase
CR541_RS10215	COG1523	belongs to the glycosyl hydrolase 13 family
CR541_RS10220	COG1609	Transcriptional regulator
CR541_RS10225	COG1126	abc transporter atp-binding protein
CR541_RS10230	COG0765	amino acid transport
CR541_RS10235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR541_RS10240	COG3942	CHAP domain
CR541_RS10245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR541_RS10255	COG1447	Phosphotransferase system cellobiose-specific component IIA
CR541_RS10265	COG3711	transcriptional antiterminator
CR541_RS10265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR541_RS10280	COG1486	melibiose metabolic process
CR541_RS10290	COG3590	peptidase
CR541_RS10295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CR541_RS10300	COG1321	iron dependent repressor
CR541_RS10300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CR541_RS10305	COG1121	(ABC) transporter
CR541_RS10320	COG0803	Belongs to the bacterial solute-binding protein 9 family
CR541_RS10355	COG1490	D-aminoacyl-tRNA deacylase activity
CR541_RS10365	COG0737	Belongs to the 5'-nucleotidase family
CR541_RS10425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CR541_RS10450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CR541_RS10480	COG0737	Belongs to the 5'-nucleotidase family
CR541_RS10490	COG1328	CTP reductase activity
CR541_RS10520	COG1438	arginine binding
CR541_RS10525	COG0018	arginyl-trna synthetase
CR541_RS10545	COG1640	4-alpha-glucanotransferase
CR541_RS10550	COG2182	Extracellular solute-binding protein
CR541_RS10555	COG1175	transmembrane transport
CR541_RS10560	COG3833	ABC-type maltose transport systems, permease component
CR541_RS10565	COG5521	maltodextrose utilization protein MalA
CR541_RS10570	COG1609	Transcriptional regulator
CR541_RS10575	COG1523	belongs to the glycosyl hydrolase 13 family
CR541_RS10580	COG1780	Probably involved in ribonucleotide reductase function
CR541_RS10585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR541_RS10590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CR541_RS10595	COG2153	protein acetylation
CR541_RS10600	COG4989	oxidoreductase activity
CR541_RS10605	COG1216	Glycosyl transferase, family 2
CR541_RS10610	COG1472	Belongs to the glycosyl hydrolase 3 family
CR541_RS10650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CR541_RS10665	COG0305	Participates in initiation and elongation during chromosome replication
CR541_RS10670	COG0359	binds to the 23S rRNA
CR541_RS10680	COG0445	tRNA wobble uridine modification
CR541_RS10695	COG1051	belongs to the nudix hydrolase family
CR541_RS10700	COG1733	regulation of RNA biosynthetic process
CR541_RS10710	COG0482	sulfurtransferase activity
CR541_RS10715	COG1760	l-serine dehydratase
CR541_RS10720	COG1760	l-serine dehydratase
CR541_RS10730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CR541_RS10735	COG1122	ATPase activity
CR541_RS10740	COG1122	ATPase activity
CR541_RS10745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CR541_RS10750	COG1426	Protein conserved in bacteria
CR541_RS10755	COG0612	Peptidase, M16
CR541_RS10760	COG0612	Peptidase, M16
CR541_RS10770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CR541_RS10775	COG0517	IMP dehydrogenase activity
CR541_RS10775	COG0516	GMP reductase activity
CR541_RS10785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR541_RS10790	COG0488	(ABC) transporter
CR541_RS10820	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CR541_RS10825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CR541_RS10830	COG1475	DNA binding
CR541_RS10835	COG0582	viral genome integration into host DNA