locus-tag	class	description
CVO91_RS00010	COG0592	DNA-directed DNA polymerase activity
CVO91_RS00035	COG0012	GTP binding
CVO91_RS00040	COG0193	aminoacyl-tRNA hydrolase activity
CVO91_RS00045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CVO91_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CVO91_RS00070	COG0037	tRNA processing
CVO91_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVO91_RS00190	COG1792	Involved in formation and maintenance of cell shape
CVO91_RS00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CVO91_RS00210	COG0436	Aminotransferase
CVO91_RS00215	COG1381	Involved in DNA repair and RecF pathway recombination
CVO91_RS00240	COG1131	(ABC) transporter
CVO91_RS00250	COG0416	fatty acid biosynthetic process
CVO91_RS00255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CVO91_RS00265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CVO91_RS00280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CVO91_RS00290	COG0138	bifunctional purine biosynthesis protein purh
CVO91_RS00325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CVO91_RS00335	COG3341	Caulimovirus viroplasmin
CVO91_RS00335	COG0328	RNA-DNA hybrid ribonuclease activity
CVO91_RS00370	COG4372	Transposase
CVO91_RS00400	COG0698	ribose 5-phosphate isomerase
CVO91_RS00405	COG0789	Transcriptional regulator
CVO91_RS00415	COG2255	four-way junction helicase activity
CVO91_RS00420	COG0546	phosphoglycolate phosphatase activity
CVO91_RS00430	COG0285	dihydrofolate synthase activity
CVO91_RS00445	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CVO91_RS00460	COG0632	four-way junction helicase activity
CVO91_RS00470	COG0519	Catalyzes the synthesis of GMP from XMP
CVO91_RS00485	COG1393	Belongs to the ArsC family
CVO91_RS00490	COG4472	Bacterial protein of unknown function (DUF965)
CVO91_RS00495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CVO91_RS00500	COG3906	Belongs to the UPF0473 family
CVO91_RS00515	COG0051	transcription antitermination factor activity, RNA binding
CVO91_RS00520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CVO91_RS00525	COG0088	Forms part of the polypeptide exit tunnel
CVO91_RS00530	COG0089	rRNA binding
CVO91_RS00535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CVO91_RS00540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CVO91_RS00545	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CVO91_RS00550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CVO91_RS00555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CVO91_RS00560	COG0255	Belongs to the universal ribosomal protein uL29 family
CVO91_RS00565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CVO91_RS00570	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CVO91_RS00575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CVO91_RS00580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CVO91_RS00585	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CVO91_RS00590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CVO91_RS00595	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CVO91_RS00600	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CVO91_RS00605	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CVO91_RS00610	COG1841	ribosomal large subunit assembly
CVO91_RS00620	COG0201	protein transport
CVO91_RS00625	COG0563	adenylate kinase activity
CVO91_RS00630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CVO91_RS00635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CVO91_RS00640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CVO91_RS00650	COG0202	RNA polymerase activity
CVO91_RS00775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CVO91_RS00800	COG4372	Transposase
CVO91_RS00820	COG1674	ftsk spoiiie
CVO91_RS00840	COG1121	(ABC) transporter
CVO91_RS00845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CVO91_RS00850	COG3443	Belongs to the bacterial solute-binding protein 9 family
CVO91_RS00850	COG0803	Belongs to the bacterial solute-binding protein 9 family
CVO91_RS00880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVO91_RS00885	COG0085	RNA polymerase activity
CVO91_RS00890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CVO91_RS00910	COG1619	proteins homologs of microcin C7 resistance protein MccF
CVO91_RS00915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CVO91_RS00920	COG1459	type II secretion system
CVO91_RS00925	COG4537	Required for transformation and DNA binding
CVO91_RS00955	COG5433	transposase activity
CVO91_RS00980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CVO91_RS01015	COG0285	dihydrofolate synthase activity
CVO91_RS01045	COG1363	Peptidase, m42
CVO91_RS01055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CVO91_RS01065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVO91_RS01090	COG0459	protein refolding
CVO91_RS01100	COG0049	tRNA binding
CVO91_RS01105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CVO91_RS01120	COG0126	phosphoglycerate kinase activity
CVO91_RS01135	COG0789	Transcriptional regulator
CVO91_RS01140	COG0174	glutamine synthetase
CVO91_RS01155	COG1396	sequence-specific DNA binding
CVO91_RS01165	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CVO91_RS01170	COG1214	PFAM Peptidase M22, glycoprotease
CVO91_RS01180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CVO91_RS01230	COG2855	membrane
CVO91_RS01240	COG1131	(ABC) transporter
CVO91_RS01250	COG2081	HI0933 family
CVO91_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
CVO91_RS01275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CVO91_RS01280	COG2222	sugar isomerase
CVO91_RS01300	COG1349	DNA-binding transcription factor activity
CVO91_RS01325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CVO91_RS01330	COG1882	Formate acetyltransferase
CVO91_RS01335	COG0366	Alpha amylase catalytic
CVO91_RS01335	COG0366	Alpha amylase catalytic
CVO91_RS01380	COG2910	NAD(P)H-binding
CVO91_RS01420	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CVO91_RS01425	COG0681	Belongs to the peptidase S26 family
CVO91_RS01455	COG0366	Alpha amylase catalytic
CVO91_RS01460	COG1263	PTS System
CVO91_RS01460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVO91_RS01465	COG2188	Transcriptional regulator
CVO91_RS01480	COG1193	negative regulation of DNA recombination
CVO91_RS01495	COG0656	L-ascorbic acid biosynthetic process
CVO91_RS01500	COG3118	belongs to the thioredoxin family
CVO91_RS01505	COG0318	PFAM AMP-dependent synthetase and ligase
CVO91_RS01510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CVO91_RS01510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CVO91_RS01520	COG1136	(ABC) transporter
CVO91_RS01525	COG1115	amino acid carrier protein
CVO91_RS01530	COG0668	transmembrane transport
CVO91_RS01545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CVO91_RS01550	COG0167	dihydroorotate dehydrogenase activity
CVO91_RS01560	COG0561	phosphatase activity
CVO91_RS01575	COG1131	(ABC) transporter
CVO91_RS01580	COG1309	transcriptional regulator
CVO91_RS01585	COG1511	domain protein
CVO91_RS01590	COG4152	abc transporter atp-binding protein
CVO91_RS01595	COG1668	transmembrane transport
CVO91_RS01620	COG1346	cytolysis
CVO91_RS01625	COG2116	formate transmembrane transporter activity
CVO91_RS01630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CVO91_RS01640	COG0494	nUDIX hydrolase
CVO91_RS01650	COG1396	sequence-specific DNA binding
CVO91_RS01655	COG0542	response to heat
CVO91_RS01680	COG1349	DNA-binding transcription factor activity
CVO91_RS01700	COG0698	ribose 5-phosphate isomerase
CVO91_RS01705	COG0698	ribose 5-phosphate isomerase
CVO91_RS01710	COG1105	Belongs to the carbohydrate kinase PfkB family
CVO91_RS01715	COG3684	Belongs to the aldolase LacD family
CVO91_RS01720	COG3711	transcriptional antiterminator
CVO91_RS01730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CVO91_RS01730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CVO91_RS01750	COG0251	oxidation-reduction process
CVO91_RS01755	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CVO91_RS01760	COG1301	dicarboxylic acid transport
CVO91_RS01770	COG1408	metallophosphoesterase
CVO91_RS01795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CVO91_RS01800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CVO91_RS01810	COG0124	histidyl-tRNA synthetase
CVO91_RS01815	COG1064	alcohol dehydrogenase
CVO91_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
CVO91_RS01820	COG1454	alcohol dehydrogenase
CVO91_RS01825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVO91_RS01840	COG4988	ABC transporter
CVO91_RS01845	COG1132	(ABC) transporter
CVO91_RS01860	COG1129	ABC transporter
CVO91_RS01865	COG0534	Mate efflux family protein
CVO91_RS01875	COG1132	(ABC) transporter
CVO91_RS01885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CVO91_RS01900	COG1304	FMN binding
CVO91_RS01905	COG1132	(ABC) transporter
CVO91_RS01910	COG1132	(ABC) transporter
CVO91_RS01915	COG3830	Belongs to the UPF0237 family
CVO91_RS01920	COG2848	UPF0210 protein
CVO91_RS01930	COG0588	phosphoglycerate mutase activity
CVO91_RS01945	COG1396	sequence-specific DNA binding
CVO91_RS01965	COG1420	regulation of RNA biosynthetic process
CVO91_RS01970	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CVO91_RS01975	COG0443	Heat shock 70 kDa protein
CVO91_RS01980	COG0484	heat shock protein binding
CVO91_RS01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVO91_RS01995	COG0765	amino acid transport
CVO91_RS02010	COG3655	Transcriptional regulator
CVO91_RS02020	COG2217	Heavy metal translocating P-type atpase
CVO91_RS02035	COG0351	phosphomethylpyrimidine kinase
CVO91_RS02045	COG4475	Protein of unknown function (DUF436)
CVO91_RS02075	COG2910	NAD(P)H-binding
CVO91_RS02105	COG0544	peptidyl-prolyl cis-trans isomerase activity
CVO91_RS02120	COG3343	RNA polymerase activity
CVO91_RS02125	COG0504	CTP synthase activity
CVO91_RS02135	COG0191	fructose-bisphosphate aldolase activity
CVO91_RS02145	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CVO91_RS02180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CVO91_RS02215	COG0436	Aminotransferase
CVO91_RS02225	COG0335	large ribosomal subunit rRNA binding
CVO91_RS02235	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CVO91_RS02240	COG0154	amidase activity
CVO91_RS02245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CVO91_RS02280	COG1609	Transcriptional regulator
CVO91_RS02285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CVO91_RS02290	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CVO91_RS02300	COG3142	Participates in the control of copper homeostasis
CVO91_RS02315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CVO91_RS02320	COG1534	Rna-binding protein
CVO91_RS02325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CVO91_RS02330	COG1713	HD superfamily hydrolase involved in NAD metabolism
CVO91_RS02340	COG1335	isochorismatase
CVO91_RS02345	COG0799	negative regulation of ribosome biogenesis
CVO91_RS02350	COG2226	methyltransferase
CVO91_RS02375	COG0789	Transcriptional regulator
CVO91_RS02380	COG2348	transferase activity, transferring amino-acyl groups
CVO91_RS02390	COG0242	peptide deformylase activity
CVO91_RS02400	COG1640	4-alpha-glucanotransferase
CVO91_RS02405	COG0058	SHG alpha-glucan phosphorylase activity
CVO91_RS02420	COG1263	PTS System
CVO91_RS02420	COG2190	(PTS) system
CVO91_RS02420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVO91_RS02425	COG0217	transcriptional regulatory protein
CVO91_RS02435	COG4720	Psort location CytoplasmicMembrane, score
CVO91_RS02445	COG1054	Belongs to the UPF0176 family
CVO91_RS02455	COG1122	ATPase activity
CVO91_RS02470	COG0357	Ribosomal RNA small subunit methyltransferase G
CVO91_RS02475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVO91_RS02480	COG3331	DNA recombination
CVO91_RS02485	COG4474	Belongs to the UPF0398 family
CVO91_RS02490	COG3599	regulation of cell shape
CVO91_RS02500	COG0116	Belongs to the methyltransferase superfamily
CVO91_RS02510	COG1854	S-ribosylhomocysteine lyase activity
CVO91_RS02515	COG1418	mRNA catabolic process
CVO91_RS02525	COG1758	RNA polymerase activity
CVO91_RS02530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CVO91_RS02535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CVO91_RS02540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CVO91_RS02540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CVO91_RS02545	COG0631	protein serine/threonine phosphatase activity
CVO91_RS02550	COG2815	serine threonine protein kinase
CVO91_RS02550	COG0515	serine threonine protein kinase
CVO91_RS02575	COG1098	S1 RNA binding domain
CVO91_RS02585	COG4974	Belongs to the 'phage' integrase family
CVO91_RS02880	COG1739	Uncharacterized protein family UPF0029
CVO91_RS02885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CVO91_RS02905	COG5433	transposase activity
CVO91_RS02980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CVO91_RS02995	COG3557	Belongs to the UPF0374 family
CVO91_RS03005	COG2188	Transcriptional regulator
CVO91_RS03015	COG2188	Transcriptional regulator
CVO91_RS03035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVO91_RS03045	COG3716	PTS system mannose fructose sorbose family IID component
CVO91_RS03060	COG0129	dihydroxy-acid dehydratase activity
CVO91_RS03065	COG2017	converts alpha-aldose to the beta-anomer
CVO91_RS03080	COG0281	malic enzyme
CVO91_RS03095	COG0392	lysyltransferase activity
CVO91_RS03095	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CVO91_RS03110	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CVO91_RS03115	COG0149	triose-phosphate isomerase activity
CVO91_RS03125	COG1078	dGTPase activity
CVO91_RS03170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CVO91_RS03180	COG2884	Cell division ATP-binding protein ftsE
CVO91_RS03185	COG2177	Part of the ABC transporter FtsEX involved in
CVO91_RS03215	COG1132	(ABC) transporter
CVO91_RS03220	COG1132	(ABC) transporter
CVO91_RS03225	COG1011	Hydrolase
CVO91_RS03245	COG1737	Transcriptional regulator
CVO91_RS03255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CVO91_RS03260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CVO91_RS03270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CVO91_RS03280	COG2814	Major facilitator Superfamily
CVO91_RS03285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CVO91_RS03295	COG0017	Asparaginyl-tRNA synthetase
CVO91_RS03300	COG0557	exoribonuclease II activity
CVO91_RS03305	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CVO91_RS03340	COG1063	alcohol dehydrogenase
CVO91_RS03355	COG2217	Heavy metal translocating P-type atpase
CVO91_RS03360	COG0110	maltose O-acetyltransferase activity
CVO91_RS03365	COG0583	DNA-binding transcription factor activity
CVO91_RS03370	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CVO91_RS03400	COG1131	(ABC) transporter
CVO91_RS03425	COG1136	(ABC) transporter
CVO91_RS03445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CVO91_RS03445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CVO91_RS03455	COG1832	CoA-binding protein
CVO91_RS03465	COG0343	queuine tRNA-ribosyltransferase activity
CVO91_RS03475	COG1609	Transcriptional regulator
CVO91_RS03490	COG0438	transferase activity, transferring glycosyl groups
CVO91_RS03505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CVO91_RS03515	COG0765	amino acid transport
CVO91_RS03520	COG0765	amino acid transport
CVO91_RS03525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVO91_RS03530	COG1126	abc transporter atp-binding protein
CVO91_RS03535	COG0745	RESPONSE REGULATOR receiver
CVO91_RS03545	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CVO91_RS03550	COG0488	(ABC) transporter
CVO91_RS03555	COG0768	penicillin binding
CVO91_RS03560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CVO91_RS03565	COG1181	Belongs to the D-alanine--D-alanine ligase family
CVO91_RS03595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CVO91_RS03605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CVO91_RS03635	COG0823	Involved in the tonB-independent uptake of proteins
CVO91_RS03640	COG0513	Belongs to the DEAD box helicase family
CVO91_RS03645	COG0640	Transcriptional regulator
CVO91_RS03665	COG2827	Endonuclease containing a URI domain
CVO91_RS03670	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CVO91_RS03690	COG0626	cystathionine gamma-synthase activity
CVO91_RS03695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CVO91_RS03700	COG2207	Transcriptional regulator
CVO91_RS03710	COG1653	transport
CVO91_RS03725	COG1653	transport
CVO91_RS03730	COG1175	transmembrane transport
CVO91_RS03735	COG0395	ABC-type sugar transport system, permease component
CVO91_RS03745	COG0366	Alpha amylase catalytic
CVO91_RS03750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CVO91_RS03765	COG0683	leucine binding
CVO91_RS03800	COG0517	IMP dehydrogenase activity
CVO91_RS03820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CVO91_RS03825	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CVO91_RS03830	COG0470	DNA polymerase III
CVO91_RS03835	COG4467	Involved in initiation control of chromosome replication
CVO91_RS03845	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CVO91_RS03860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CVO91_RS03865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CVO91_RS03870	COG1393	Belongs to the ArsC family
CVO91_RS03910	COG0708	Exodeoxyribonuclease III
CVO91_RS03920	COG0531	amino acid
CVO91_RS03975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVO91_RS03975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVO91_RS04000	COG4122	O-methyltransferase activity
CVO91_RS04005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CVO91_RS04015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CVO91_RS04025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVO91_RS04040	COG1476	TRANSCRIPTIONal
CVO91_RS04075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVO91_RS04080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVO91_RS04085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CVO91_RS04090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CVO91_RS04095	COG0372	Belongs to the citrate synthase family
CVO91_RS04100	COG0538	isocitrate dehydrogenase activity
CVO91_RS04105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVO91_RS04115	COG1012	belongs to the aldehyde dehydrogenase family
CVO91_RS04150	COG1196	nuclear chromosome segregation
CVO91_RS04155	COG0561	phosphatase activity
CVO91_RS04160	COG0561	phosphatase activity
CVO91_RS04165	COG0552	protein localization to endoplasmic reticulum
CVO91_RS04190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CVO91_RS04195	COG3689	TIGRFAM TIGR03943 family protein
CVO91_RS04200	COG0701	Predicted permease
CVO91_RS04210	COG1597	lipid kinase activity
CVO91_RS04220	COG0356	it plays a direct role in the translocation of protons across the membrane
CVO91_RS04225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CVO91_RS04230	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CVO91_RS04235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CVO91_RS04240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CVO91_RS04245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CVO91_RS04250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CVO91_RS04260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CVO91_RS04275	COG2211	Major facilitator Superfamily
CVO91_RS04285	COG3250	beta-galactosidase activity
CVO91_RS04295	COG0800	Aldolase
CVO91_RS04305	COG1312	Catalyzes the dehydration of D-mannonate
CVO91_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
CVO91_RS04345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVO91_RS04345	COG0072	phenylalanine-tRNA ligase activity
CVO91_RS04375	COG1051	belongs to the nudix hydrolase family
CVO91_RS04400	COG2807	transmembrane transport
CVO91_RS04410	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CVO91_RS04415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CVO91_RS04425	COG1234	tRNA 3'-trailer cleavage
CVO91_RS04430	COG0300	oxidoreductase activity
CVO91_RS04435	COG2217	Heavy metal translocating P-type atpase
CVO91_RS04440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CVO91_RS04445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CVO91_RS04445	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CVO91_RS04465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CVO91_RS04480	COG2384	SAM-dependent methyltransferase
CVO91_RS04485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CVO91_RS04495	COG0640	Transcriptional regulator
CVO91_RS04500	COG1902	pentaerythritol trinitrate reductase activity
CVO91_RS04515	COG0772	Belongs to the SEDS family
CVO91_RS04520	COG0693	protein deglycase activity
CVO91_RS04525	COG0187	DNA topoisomerase II activity
CVO91_RS04530	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CVO91_RS04535	COG0560	Phosphoserine phosphatase
CVO91_RS04625	COG2706	6-phosphogluconolactonase activity
CVO91_RS04630	COG0628	permease
CVO91_RS04640	COG3527	Alpha-acetolactate decarboxylase
CVO91_RS04645	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CVO91_RS04665	COG3842	ATPase activity
CVO91_RS04670	COG1442	glycosyl transferase family 8
CVO91_RS04670	COG1216	Glycosyl transferase, family 2
CVO91_RS04740	COG1216	Glycosyl transferase, family 2
CVO91_RS04740	COG1442	glycosyl transferase family 8
CVO91_RS04755	COG0438	transferase activity, transferring glycosyl groups
CVO91_RS04760	COG1442	glycosyl transferase family 8
CVO91_RS04760	COG1216	Glycosyl transferase, family 2
CVO91_RS04765	COG1442	glycosyl transferase family 8
CVO91_RS04775	COG0201	protein transport
CVO91_RS04830	COG1181	Belongs to the D-alanine--D-alanine ligase family
CVO91_RS04860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CVO91_RS04870	COG1131	(ABC) transporter
CVO91_RS04875	COG2188	Transcriptional regulator
CVO91_RS04885	COG0205	6-phosphofructokinase activity
CVO91_RS04890	COG0469	pyruvate kinase activity
CVO91_RS04905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVO91_RS04925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CVO91_RS04930	COG0765	amino acid transport
CVO91_RS04935	COG1126	abc transporter atp-binding protein
CVO91_RS04940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVO91_RS04975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CVO91_RS04985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CVO91_RS05010	COG0698	ribose 5-phosphate isomerase
CVO91_RS05015	COG0698	ribose 5-phosphate isomerase
CVO91_RS05035	COG1368	sulfuric ester hydrolase activity
CVO91_RS05040	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CVO91_RS05045	COG0710	3-dehydroquinate dehydratase activity
CVO91_RS05050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CVO91_RS05055	COG0287	Prephenate dehydrogenase
CVO91_RS05060	COG3679	Belongs to the UPF0342 family
CVO91_RS05070	COG3684	Belongs to the aldolase LacD family
CVO91_RS05115	COG4120	Belongs to the binding-protein-dependent transport system permease family
CVO91_RS05120	COG1116	anion transmembrane transporter activity
CVO91_RS05120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CVO91_RS05135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CVO91_RS05150	COG1846	Transcriptional regulator
CVO91_RS05155	COG3759	membrane
CVO91_RS05175	COG1695	Transcriptional regulator
CVO91_RS05190	COG2195	Cleaves the N-terminal amino acid of tripeptides
CVO91_RS05195	COG0561	phosphatase activity
CVO91_RS05215	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CVO91_RS05230	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CVO91_RS05235	COG0196	riboflavin kinase activity
CVO91_RS05240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CVO91_RS05245	COG1393	Belongs to the ArsC family
CVO91_RS05250	COG4476	Belongs to the UPF0223 family
CVO91_RS05255	COG0483	inositol monophosphate 1-phosphatase activity
CVO91_RS05260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CVO91_RS05260	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CVO91_RS05270	COG0573	inorganic phosphate transmembrane transporter activity
CVO91_RS05275	COG0581	inorganic phosphate transmembrane transporter activity
CVO91_RS05280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CVO91_RS05285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CVO91_RS05300	COG0745	RESPONSE REGULATOR receiver
CVO91_RS05305	COG5002	protein histidine kinase activity
CVO91_RS05320	COG1072	(Pantothenic acid kinase))
CVO91_RS05325	COG2813	Specifically methylates the guanine in position
CVO91_RS05330	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CVO91_RS05340	COG0295	cytidine deaminase activity
CVO91_RS05345	COG1744	ABC transporter substrate-binding protein PnrA-like
CVO91_RS05350	COG3845	ABC transporter
CVO91_RS05355	COG4603	Belongs to the binding-protein-dependent transport system permease family
CVO91_RS05360	COG1079	Belongs to the binding-protein-dependent transport system permease family
CVO91_RS05365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CVO91_RS05370	COG0039	L-malate dehydrogenase activity
CVO91_RS05375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CVO91_RS05380	COG3764	Sortase (surface protein transpeptidase)
CVO91_RS05400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CVO91_RS05410	COG0489	protein tyrosine kinase activity
CVO91_RS05415	COG0438	transferase activity, transferring glycosyl groups
CVO91_RS05450	COG3955	Domain of unknown function (DUF1919)
CVO91_RS05490	COG1215	transferase activity, transferring glycosyl groups
CVO91_RS05495	COG1442	glycosyl transferase family 8
CVO91_RS05495	COG1216	Glycosyl transferase, family 2
CVO91_RS05500	COG1216	Glycosyl transferase, family 2
CVO91_RS05505	COG1216	Glycosyl transferase, family 2
CVO91_RS05510	COG0463	Glycosyl transferase, family 2
CVO91_RS05540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CVO91_RS05545	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CVO91_RS05560	COG1104	cysteine desulfurase activity
CVO91_RS05570	COG4116	CYTH
CVO91_RS05575	COG2357	RelA SpoT domain protein
CVO91_RS05580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CVO91_RS05585	COG0564	pseudouridine synthase activity
CVO91_RS05590	COG0280	phosphate acetyltransferase
CVO91_RS05595	COG1132	(ABC) transporter
CVO91_RS05600	COG1132	(ABC) transporter
CVO91_RS05610	COG1194	a g-specific adenine glycosylase
CVO91_RS05620	COG1396	sequence-specific DNA binding
CVO91_RS05640	COG1454	alcohol dehydrogenase
CVO91_RS05645	COG2873	o-acetylhomoserine
CVO91_RS05650	COG0488	(ABC) transporter
CVO91_RS05660	COG1126	abc transporter atp-binding protein
CVO91_RS05675	COG3583	domain protein
CVO91_RS05680	COG4372	Transposase
CVO91_RS05730	COG0647	UMP catabolic process
CVO91_RS05740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CVO91_RS05745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CVO91_RS05750	COG1970	mechanosensitive ion channel activity
CVO91_RS05755	COG0358	DNA primase activity
CVO91_RS05760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CVO91_RS05765	COG2151	metal-sulfur cluster biosynthetic enzyme
CVO91_RS05780	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CVO91_RS05790	COG0135	phosphoribosylanthranilate isomerase activity
CVO91_RS05795	COG1088	dTDP-glucose 4,6-dehydratase activity
CVO91_RS05800	COG1091	dTDP-4-dehydrorhamnose reductase activity
CVO91_RS05860	COG1070	Carbohydrate kinase
CVO91_RS05880	COG1175	transmembrane transport
CVO91_RS05885	COG0395	ABC-type sugar transport system, permease component
CVO91_RS05900	COG1940	carbohydrate kinase activity
CVO91_RS05910	COG0582	viral genome integration into host DNA
CVO91_RS05915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CVO91_RS05920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CVO91_RS05930	COG1272	protein, Hemolysin III
CVO91_RS05940	COG0425	Belongs to the sulfur carrier protein TusA family
CVO91_RS05940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CVO91_RS05945	COG0110	maltose O-acetyltransferase activity
CVO91_RS05950	COG0758	DNA mediated transformation
CVO91_RS05955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CVO91_RS05965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CVO91_RS05970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CVO91_RS05995	COG0564	pseudouridine synthase activity
CVO91_RS06000	COG2824	Alkylphosphonate utilization operon protein PhnA
CVO91_RS06010	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CVO91_RS06015	COG0540	Belongs to the ATCase OTCase family
CVO91_RS06020	COG0505	Belongs to the CarA family
CVO91_RS06040	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CVO91_RS06050	COG0228	four-way junction DNA binding
CVO91_RS06065	COG1132	(ABC) transporter
CVO91_RS06070	COG0726	polysaccharide deacetylase
CVO91_RS06075	COG0460	homoserine dehydrogenase
CVO91_RS06080	COG0083	homoserine kinase activity
CVO91_RS06085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CVO91_RS06090	COG3842	ATPase activity
CVO91_RS06095	COG1176	ABC-type spermidine putrescine transport system, permease component I
CVO91_RS06100	COG1177	transmembrane transport
CVO91_RS06110	COG0038	chloride channel
CVO91_RS06135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CVO91_RS06140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CVO91_RS06160	COG1136	(ABC) transporter
CVO91_RS06160	COG0577	efflux transmembrane transporter activity
CVO91_RS06170	COG0534	Mate efflux family protein
CVO91_RS06180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CVO91_RS06185	COG0336	Belongs to the RNA methyltransferase TrmD family
CVO91_RS06190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CVO91_RS06195	COG1349	DNA-binding transcription factor activity
CVO91_RS06200	COG1105	Belongs to the carbohydrate kinase PfkB family
CVO91_RS06205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVO91_RS06205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVO91_RS06205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVO91_RS06210	COG3583	domain protein
CVO91_RS06220	COG1307	EDD domain protein, DegV family
CVO91_RS06225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CVO91_RS06230	COG0617	tRNA 3'-terminal CCA addition
CVO91_RS06235	COG0488	(ABC) transporter
CVO91_RS06245	COG1940	carbohydrate kinase activity
CVO91_RS06260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CVO91_RS06265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CVO91_RS06275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CVO91_RS06290	COG0481	GTPase activity
CVO91_RS06310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CVO91_RS06315	COG2890	protein-(glutamine-N5) methyltransferase activity
CVO91_RS06320	COG0009	L-threonylcarbamoyladenylate synthase
CVO91_RS06330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CVO91_RS06340	COG0741	lytic transglycosylase activity
CVO91_RS06345	COG4221	oxidoreductase activity
CVO91_RS06370	COG1401	restriction endodeoxyribonuclease activity
CVO91_RS06375	COG4268	DNA restriction-modification system
CVO91_RS06380	COG0519	Catalyzes the synthesis of GMP from XMP
CVO91_RS06380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CVO91_RS06385	COG2188	Transcriptional regulator
CVO91_RS06390	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CVO91_RS06395	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CVO91_RS06420	COG4974	Belongs to the 'phage' integrase family
CVO91_RS06430	COG5002	protein histidine kinase activity
CVO91_RS06435	COG0745	RESPONSE REGULATOR receiver
CVO91_RS06455	COG1136	(ABC) transporter
CVO91_RS06495	COG2382	esterase
CVO91_RS06500	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CVO91_RS06505	COG0647	UMP catabolic process
CVO91_RS06510	COG4974	Belongs to the 'phage' integrase family
CVO91_RS06570	COG1131	(ABC) transporter
CVO91_RS06590	COG3843	relaxase mobilization nuclease domain protein
CVO91_RS06705	COG1192	Involved in chromosome partitioning
CVO91_RS06745	COG4443	Transcriptional Coactivator p15 (PC4)
CVO91_RS06755	COG1475	DNA binding
CVO91_RS06830	COG1192	Involved in chromosome partitioning
CVO91_RS06965	COG0270	DNA (cytosine-5-)-methyltransferase activity
CVO91_RS06985	COG0222	ribosome binding
CVO91_RS06990	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CVO91_RS06995	COG1114	Component of the transport system for branched-chain amino acids
CVO91_RS07000	COG0301	tRNA thio-modification
CVO91_RS07005	COG1104	cysteine desulfurase activity
CVO91_RS07040	COG0539	negative regulation of cytoplasmic translation
CVO91_RS07060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CVO91_RS07070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CVO91_RS07100	COG2184	nucleotidyltransferase activity
CVO91_RS07105	COG0187	DNA topoisomerase II activity
CVO91_RS07155	COG1216	Glycosyl transferase, family 2
CVO91_RS07155	COG1442	glycosyl transferase family 8
CVO91_RS07195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVO91_RS07200	COG0673	inositol 2-dehydrogenase activity
CVO91_RS07205	COG4409	exo-alpha-(2->6)-sialidase activity
CVO91_RS07215	COG1175	transmembrane transport
CVO91_RS07235	COG1737	Transcriptional regulator
CVO91_RS07255	COG0424	maF-like protein
CVO91_RS07260	COG0737	Belongs to the 5'-nucleotidase family
CVO91_RS07270	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CVO91_RS07275	COG0463	Glycosyl transferase, family 2
CVO91_RS07290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CVO91_RS07295	COG0284	orotidine-5'-phosphate decarboxylase activity
CVO91_RS07300	COG0167	dihydroorotate dehydrogenase activity
CVO91_RS07305	COG0543	2 iron, 2 sulfur cluster binding
CVO91_RS07315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CVO91_RS07325	COG0297	glycogen (starch) synthase activity
CVO91_RS07335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVO91_RS07340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVO91_RS07380	COG1074	ATP-dependent DNA helicase activity
CVO91_RS07385	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CVO91_RS07425	COG1131	(ABC) transporter
CVO91_RS07455	COG1011	Hydrolase
CVO91_RS07470	COG0210	DNA helicase
CVO91_RS07475	COG3177	Filamentation induced by cAMP protein fic
CVO91_RS07490	COG1164	Oligoendopeptidase f
CVO91_RS07500	COG0346	lactoylglutathione lyase activity
CVO91_RS07505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CVO91_RS07515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVO91_RS07520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CVO91_RS07545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CVO91_RS07555	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CVO91_RS07565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CVO91_RS07570	COG4684	Psort location CytoplasmicMembrane, score
CVO91_RS07575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CVO91_RS07590	COG4106	trans-aconitate 2-methyltransferase activity
CVO91_RS07635	COG1388	LysM domain
CVO91_RS07635	COG0860	N-Acetylmuramoyl-L-alanine amidase
CVO91_RS07705	COG0740	serine-type endopeptidase activity
CVO91_RS07710	COG4695	Portal protein
CVO91_RS07750	COG0270	DNA (cytosine-5-)-methyltransferase activity
CVO91_RS07775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CVO91_RS07825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CVO91_RS07825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CVO91_RS07885	COG0456	acetyltransferase
CVO91_RS07900	COG1192	Involved in chromosome partitioning
CVO91_RS07905	COG0551	DNA topoisomerase type I activity
CVO91_RS07905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CVO91_RS07915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CVO91_RS07925	COG2226	methyltransferase
CVO91_RS07945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CVO91_RS07955	COG0077	Prephenate dehydratase
CVO91_RS07960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CVO91_RS07970	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVO91_RS07975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVO91_RS07980	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CVO91_RS07985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CVO91_RS08005	COG1131	(ABC) transporter
CVO91_RS08040	COG1216	Glycosyl transferase, family 2
CVO91_RS08070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CVO91_RS08080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CVO91_RS08090	COG3341	Caulimovirus viroplasmin
CVO91_RS08090	COG0328	RNA-DNA hybrid ribonuclease activity
CVO91_RS08100	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CVO91_RS08125	COG0058	SHG alpha-glucan phosphorylase activity
CVO91_RS08130	COG0813	purine-nucleoside phosphorylase activity
CVO91_RS08135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CVO91_RS08145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CVO91_RS08150	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CVO91_RS08175	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CVO91_RS08180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CVO91_RS08190	COG1704	LemA family
CVO91_RS08200	COG1573	uracil-dna glycosylase
CVO91_RS08220	COG2226	methyltransferase
CVO91_RS08225	COG0488	(ABC) transporter
CVO91_RS08230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CVO91_RS08245	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CVO91_RS08250	COG3442	glutamine amidotransferase
CVO91_RS08255	COG2226	methyltransferase
CVO91_RS08270	COG0488	(ABC) transporter
CVO91_RS08275	COG0210	DNA helicase
CVO91_RS08375	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CVO91_RS08380	COG0716	FMN binding
CVO91_RS08390	COG1605	Chorismate mutase
CVO91_RS08390	COG0287	Prephenate dehydrogenase
CVO91_RS08395	COG0038	chloride channel
CVO91_RS08415	COG0737	Belongs to the 5'-nucleotidase family
CVO91_RS08425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CVO91_RS08430	COG1466	dna polymerase III delta subunit
CVO91_RS08445	COG2333	competence protein COMEC
CVO91_RS08445	COG0658	competence protein
CVO91_RS08450	COG1555	photosystem II stabilization
CVO91_RS08450	COG1596	polysaccharide export
CVO91_RS08455	COG0204	Acyl-transferase
CVO91_RS08460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CVO91_RS08470	COG1120	ATPase activity
CVO91_RS08475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CVO91_RS08480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVO91_RS08485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVO91_RS08495	COG0386	Belongs to the glutathione peroxidase family
CVO91_RS08500	COG1187	pseudouridine synthase activity
CVO91_RS08505	COG0435	Glutathione S-transferase
CVO91_RS08515	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CVO91_RS08520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CVO91_RS08525	COG1696	Membrane protein involved in D-alanine export
CVO91_RS08530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVO91_RS08550	COG0363	glucosamine-6-phosphate deaminase activity
CVO91_RS08560	COG1438	arginine binding
CVO91_RS08565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVO91_RS08570	COG1288	antiporter activity
CVO91_RS08575	COG0549	Belongs to the carbamate kinase family
CVO91_RS08580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CVO91_RS08585	COG0454	-acetyltransferase
CVO91_RS08600	COG1481	regulation of sporulation
CVO91_RS08605	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CVO91_RS08610	COG1660	Displays ATPase and GTPase activities
CVO91_RS08615	COG0251	oxidation-reduction process
CVO91_RS08640	COG0436	Aminotransferase
CVO91_RS08660	COG0562	UDP-galactopyranose mutase
CVO91_RS08690	COG4750	Nucleotidyl transferase
CVO91_RS08710	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CVO91_RS08715	COG3475	LICD family
CVO91_RS08740	COG1216	Glycosyl transferase, family 2
CVO91_RS08740	COG1442	glycosyl transferase family 8
CVO91_RS08760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CVO91_RS08765	COG3177	Filamentation induced by cAMP protein fic
CVO91_RS08775	COG4464	protein tyrosine phosphatase activity
CVO91_RS08785	COG3944	biosynthesis protein
CVO91_RS08790	COG1316	TRANSCRIPTIONal
CVO91_RS08795	COG3022	response to hydroperoxide
CVO91_RS08800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVO91_RS08820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CVO91_RS08825	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CVO91_RS08830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CVO91_RS08855	COG1702	phosphate starvation-inducible protein PhoH
CVO91_RS08860	COG3583	domain protein
CVO91_RS08865	COG4479	Belongs to the UPF0346 family
CVO91_RS08880	COG2996	Protein conserved in bacteria
CVO91_RS08885	COG0233	cytoplasmic translational termination
CVO91_RS08890	COG0528	UMP kinase activity
CVO91_RS08895	COG2244	polysaccharide biosynthetic process
CVO91_RS08900	COG0625	glutathione transferase activity
CVO91_RS08925	COG0346	lactoylglutathione lyase activity
CVO91_RS08930	COG0697	spore germination
CVO91_RS08930	COG1674	ftsk spoiiie
CVO91_RS08935	COG1621	beta-fructofuranosidase activity
CVO91_RS08940	COG1653	transport
CVO91_RS08950	COG0395	ABC-type sugar transport system, permease component
CVO91_RS08955	COG4209	transmembrane transport
CVO91_RS08980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CVO91_RS09005	COG0494	nUDIX hydrolase
CVO91_RS09010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CVO91_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
CVO91_RS09065	COG0577	efflux transmembrane transporter activity
CVO91_RS09070	COG1136	(ABC) transporter
CVO91_RS09075	COG2205	protein histidine kinase activity
CVO91_RS09090	COG0436	Aminotransferase
CVO91_RS09100	COG1732	Glycine betaine
CVO91_RS09105	COG1125	glycine betaine transport
CVO91_RS09105	COG0517	IMP dehydrogenase activity
CVO91_RS09125	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CVO91_RS09130	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CVO91_RS09135	COG1482	cell wall glycoprotein biosynthetic process
CVO91_RS09155	COG3091	SprT-like family
CVO91_RS09160	COG2183	response to ionizing radiation
CVO91_RS09165	COG0656	L-ascorbic acid biosynthetic process
CVO91_RS09170	COG4708	membrane
CVO91_RS09185	COG0024	Methionine aminopeptidase
CVO91_RS09195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CVO91_RS09200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CVO91_RS09205	COG2131	deaminase
CVO91_RS09215	COG1363	Peptidase, m42
CVO91_RS09230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CVO91_RS09235	COG1956	GAF domain-containing protein
CVO91_RS09250	COG1695	Transcriptional regulator
CVO91_RS09260	COG0673	inositol 2-dehydrogenase activity
CVO91_RS09265	COG0513	Belongs to the DEAD box helicase family
CVO91_RS09270	COG0726	polysaccharide deacetylase
CVO91_RS09275	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CVO91_RS09280	COG0772	Belongs to the SEDS family
CVO91_RS09300	COG3859	Proton-coupled thiamine transporter YuaJ
CVO91_RS09310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CVO91_RS09320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CVO91_RS09335	COG0436	Aminotransferase
CVO91_RS09345	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CVO91_RS09365	COG3547	Transposase (IS116 IS110 IS902 family)
CVO91_RS09370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CVO91_RS09380	COG0765	amino acid transport
CVO91_RS09385	COG4703	Protein of unknown function (DUF1797)
CVO91_RS09390	COG0542	response to heat
CVO91_RS09395	COG0494	nUDIX hydrolase
CVO91_RS09395	COG0406	alpha-ribazole phosphatase activity
CVO91_RS09415	COG3599	regulation of cell shape
CVO91_RS09430	COG1799	cell septum assembly
CVO91_RS09435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CVO91_RS09440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CVO91_RS09455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CVO91_RS09475	COG1217	gtp-binding protein TYPA
CVO91_RS09485	COG3547	Transposase (IS116 IS110 IS902 family)
CVO91_RS09495	COG0776	regulation of translation
CVO91_RS09505	COG2755	lipolytic protein G-D-S-L family
CVO91_RS09510	COG1307	EDD domain protein, DegV family
CVO91_RS09515	COG0497	DNA recombination
CVO91_RS09520	COG1438	arginine binding
CVO91_RS09525	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CVO91_RS09535	COG1722	exodeoxyribonuclease VII activity
CVO91_RS09540	COG1570	exodeoxyribonuclease VII activity
CVO91_RS09610	COG0346	lactoylglutathione lyase activity
CVO91_RS09630	COG5433	transposase activity
CVO91_RS09655	COG0183	Belongs to the thiolase family
CVO91_RS09660	COG3425	synthase
CVO91_RS09690	COG0577	efflux transmembrane transporter activity
CVO91_RS09695	COG1136	(ABC) transporter
CVO91_RS09700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVO91_RS09705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CVO91_RS09710	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CVO91_RS09715	COG1268	BioY protein
CVO91_RS09720	COG4443	Transcriptional Coactivator p15 (PC4)
CVO91_RS09730	COG0826	peptidase U32
CVO91_RS09745	COG0789	Transcriptional regulator
CVO91_RS09755	COG1227	inorganic diphosphatase activity
CVO91_RS09765	COG1733	regulation of RNA biosynthetic process
CVO91_RS09770	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CVO91_RS09790	COG2514	catechol 2,3-dioxygenase activity
CVO91_RS09800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CVO91_RS09805	COG1253	flavin adenine dinucleotide binding
CVO91_RS09810	COG1119	ATPase activity
CVO91_RS09815	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CVO91_RS09835	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CVO91_RS09840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CVO91_RS09845	COG0133	tryptophan synthase activity
CVO91_RS09870	COG4470	Protein conserved in bacteria
CVO91_RS09875	COG3480	Lon protease (S16) C-terminal proteolytic domain
CVO91_RS09880	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CVO91_RS09885	COG0742	ribosomal rna small subunit methyltransferase
CVO91_RS09895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CVO91_RS09900	COG4483	Protein conserved in bacteria
CVO91_RS09905	COG2197	response regulator
CVO91_RS09910	COG4585	Histidine kinase
CVO91_RS09910	COG2203	Gaf domain
CVO91_RS09915	COG0842	Transport permease protein
CVO91_RS09920	COG1131	(ABC) transporter
CVO91_RS09935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CVO91_RS09950	COG0671	phosphoesterase, PA-phosphatase related
CVO91_RS09955	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CVO91_RS09970	COG0747	negative chemotaxis
CVO91_RS09975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CVO91_RS09980	COG1187	pseudouridine synthase activity
CVO91_RS09985	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CVO91_RS09990	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CVO91_RS09995	COG0582	viral genome integration into host DNA
CVO91_RS10015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CVO91_RS10020	COG3763	UPF0154 protein
CVO91_RS10030	COG3579	cysteine-type endopeptidase activity
CVO91_RS10045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVO91_RS10050	COG1254	Belongs to the acylphosphatase family
CVO91_RS10055	COG0706	membrane insertase activity
CVO91_RS10060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CVO91_RS10065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CVO91_RS10075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CVO91_RS10085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CVO91_RS10110	COG1160	GTP binding
CVO91_RS10120	COG1484	DNA-dependent DNA replication
CVO91_RS10130	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CVO91_RS10135	COG0628	permease
CVO91_RS10140	COG0745	RESPONSE REGULATOR receiver
CVO91_RS10145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CVO91_RS10155	COG0492	ferredoxin-NADP+ reductase activity
CVO91_RS10165	COG0513	Belongs to the DEAD box helicase family
CVO91_RS10175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CVO91_RS10180	COG0768	penicillin binding
CVO91_RS10190	COG0275	rRNA processing
CVO91_RS10245	COG4939	FMN-binding domain protein
CVO91_RS10250	COG0142	geranyltranstransferase activity
CVO91_RS10255	COG1252	NADH dehydrogenase
CVO91_RS10270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CVO91_RS10275	COG0569	domain protein
CVO91_RS10280	COG0534	Mate efflux family protein
CVO91_RS10300	COG0751	glycine-tRNA ligase activity
CVO91_RS10320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CVO91_RS10325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVO91_RS10330	COG1464	Belongs to the NlpA lipoprotein family
CVO91_RS10335	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CVO91_RS10345	COG0444	Belongs to the ABC transporter superfamily
CVO91_RS10350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVO91_RS10355	COG0601	transmembrane transport
CVO91_RS10365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CVO91_RS10375	COG2252	PERMEase
CVO91_RS10380	COG0561	phosphatase activity
CVO91_RS10390	COG3715	PTS system
CVO91_RS10395	COG3716	PTS system mannose fructose sorbose family IID component
CVO91_RS10420	COG3177	Filamentation induced by cAMP protein fic
CVO91_RS10430	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CVO91_RS10445	COG1266	CAAX protease self-immunity
CVO91_RS10465	COG0439	Biotin carboxylase
CVO91_RS10485	COG1028	Short-chain dehydrogenase reductase Sdr
CVO91_RS10500	COG2070	2-Nitropropane dioxygenase
CVO91_RS10510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CVO91_RS10520	COG1024	Enoyl-CoA hydratase
CVO91_RS10525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVO91_RS10530	COG0527	aspartate kinase activity
CVO91_RS10535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CVO91_RS10540	COG0736	holo-[acyl-carrier-protein] synthase activity
CVO91_RS10545	COG0653	protein targeting
CVO91_RS10560	COG1940	carbohydrate kinase activity
CVO91_RS10565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVO91_RS10565	COG1263	PTS System
CVO91_RS10565	COG2190	(PTS) system
CVO91_RS10570	COG1621	beta-fructofuranosidase activity
CVO91_RS10575	COG1609	Transcriptional regulator
CVO91_RS10580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CVO91_RS10595	COG0006	proline dipeptidase activity
CVO91_RS10620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CVO91_RS10635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CVO91_RS10640	COG0629	single-stranded DNA binding
CVO91_RS10650	COG0095	Lipoate-protein ligase
CVO91_RS10660	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVO91_RS10670	COG0022	dehydrogenase e1 component
CVO91_RS10670	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVO91_RS10675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CVO91_RS10680	COG2860	membrane
CVO91_RS10695	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CVO91_RS10700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CVO91_RS10710	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CVO91_RS10715	COG0195	Participates in both transcription termination and antitermination
CVO91_RS10730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CVO91_RS10740	COG4473	ABC transporter
CVO91_RS10745	COG1131	(ABC) transporter
CVO91_RS10750	COG0537	adenosine 5'-monophosphoramidase activity
CVO91_RS10765	COG1316	TRANSCRIPTIONal
CVO91_RS10775	COG0802	atpase or kinase
CVO91_RS10780	COG1461	Dihydroxyacetone kinase
CVO91_RS10795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVO91_RS10800	COG0601	transmembrane transport
CVO91_RS10805	COG4608	Belongs to the ABC transporter superfamily
CVO91_RS10820	COG1686	Belongs to the peptidase S11 family
CVO91_RS10835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CVO91_RS10840	COG0719	Fe-S assembly protein
CVO91_RS10850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CVO91_RS10855	COG4862	establishment of competence for transformation
CVO91_RS10860	COG1968	undecaprenyl-diphosphatase activity
CVO91_RS10865	COG0765	amino acid transport
CVO91_RS10875	COG4372	Transposase
CVO91_RS10905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CVO91_RS10910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CVO91_RS10915	COG0440	acetolactate synthase activity
CVO91_RS10920	COG0028	Belongs to the TPP enzyme family
CVO91_RS10925	COG0463	Glycosyl transferase, family 2
CVO91_RS10940	COG0129	dihydroxy-acid dehydratase activity
CVO91_RS10955	COG2151	metal-sulfur cluster biosynthetic enzyme
CVO91_RS11010	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CVO91_RS11030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVO91_RS11070	COG3842	ATPase activity
CVO91_RS11080	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CVO91_RS11105	COG1045	serine acetyltransferase
CVO91_RS11110	COG1185	polyribonucleotide nucleotidyltransferase activity
CVO91_RS11115	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CVO91_RS11145	COG0464	growth
CVO91_RS11170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CVO91_RS11175	COG1187	pseudouridine synthase activity
CVO91_RS11195	COG0126	phosphoglycerate kinase activity
CVO91_RS11210	COG0242	peptide deformylase activity
CVO91_RS11230	COG1136	(ABC) transporter
CVO91_RS11245	COG0066	3-isopropylmalate dehydratase activity
CVO91_RS11255	COG0473	3-isopropylmalate dehydrogenase activity
CVO91_RS11270	COG2309	aminopeptidase activity
CVO91_RS11320	COG2176	DNA-directed DNA polymerase activity
CVO91_RS11325	COG0616	signal peptide processing
CVO91_RS11330	COG0442	prolyl-tRNA aminoacylation
CVO91_RS11340	COG4589	Belongs to the CDS family
CVO91_RS11345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CVO91_RS11350	COG1862	Preprotein translocase
CVO91_RS11360	COG2918	glutathione biosynthetic process
CVO91_RS11360	COG1181	Belongs to the D-alanine--D-alanine ligase family
CVO91_RS11370	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CVO91_RS11375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CVO91_RS11385	COG0542	response to heat
CVO91_RS11390	COG4463	regulation of RNA biosynthetic process
CVO91_RS11405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CVO91_RS11430	COG1609	Transcriptional regulator
CVO91_RS11435	COG0641	radical SAM
CVO91_RS11450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CVO91_RS11470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CVO91_RS11475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVO91_RS11480	COG0492	ferredoxin-NADP+ reductase activity
CVO91_RS11485	COG0564	pseudouridine synthase activity
CVO91_RS11490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CVO91_RS11510	COG1564	THIamine pyrophosphokinase
CVO91_RS11520	COG1162	GTPase activity
CVO91_RS11540	COG1132	(ABC) transporter
CVO91_RS11570	COG4115	mRNA cleavage
CVO91_RS11610	COG0084	hydrolase, TatD family'
CVO91_RS11620	COG1847	R3H domain protein
CVO91_RS11630	COG0594	ribonuclease P activity
CVO91_RS11635	COG0165	Argininosuccinate lyase
CVO91_RS11640	COG0137	argininosuccinate synthase activity
CVO91_RS11660	COG2040	homocysteine
CVO91_RS11665	COG0833	amino acid
CVO91_RS11700	COG3764	Sortase (surface protein transpeptidase)
CVO91_RS11755	COG0756	dUTP diphosphatase activity
CVO91_RS11780	COG0577	efflux transmembrane transporter activity
CVO91_RS11780	COG1136	(ABC) transporter
CVO91_RS11805	COG2832	Protein of unknown function (DUF454)
CVO91_RS11815	COG3976	FMN-binding domain protein
CVO91_RS11815	COG0431	NADPH-dependent FMN reductase
CVO91_RS11815	COG1053	succinate dehydrogenase
CVO91_RS11825	COG1132	(ABC) transporter
CVO91_RS11830	COG1132	(ABC) transporter
CVO91_RS11840	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CVO91_RS11845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CVO91_RS11850	COG0705	Rhomboid family
CVO91_RS11855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CVO91_RS11860	COG1473	amidohydrolase
CVO91_RS11865	COG2171	N-acyltransferase activity
CVO91_RS11885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CVO91_RS11915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CVO91_RS11940	COG3623	hexulose-6-phosphate isomerase
CVO91_RS11965	COG1523	belongs to the glycosyl hydrolase 13 family
CVO91_RS11975	COG1609	Transcriptional regulator
CVO91_RS11990	COG3942	CHAP domain
CVO91_RS11995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CVO91_RS12005	COG1447	Phosphotransferase system cellobiose-specific component IIA
CVO91_RS12015	COG3711	transcriptional antiterminator
CVO91_RS12015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVO91_RS12025	COG2723	6-phospho-beta-galactosidase activity
CVO91_RS12030	COG1486	melibiose metabolic process
CVO91_RS12050	COG5433	transposase activity
CVO91_RS12060	COG5433	transposase activity
CVO91_RS12075	COG1215	transferase activity, transferring glycosyl groups
CVO91_RS12095	COG3590	peptidase
CVO91_RS12100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CVO91_RS12105	COG1321	iron dependent repressor
CVO91_RS12105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CVO91_RS12110	COG1121	(ABC) transporter
CVO91_RS12125	COG0803	Belongs to the bacterial solute-binding protein 9 family
CVO91_RS12195	COG3290	protein histidine kinase activity
CVO91_RS12220	COG1490	D-aminoacyl-tRNA deacylase activity
CVO91_RS12230	COG0737	Belongs to the 5'-nucleotidase family
CVO91_RS12245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CVO91_RS12270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CVO91_RS12305	COG1328	CTP reductase activity
CVO91_RS12330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CVO91_RS12355	COG1438	arginine binding
CVO91_RS12360	COG0018	arginyl-trna synthetase
CVO91_RS12405	COG1131	(ABC) transporter
CVO91_RS12420	COG1640	4-alpha-glucanotransferase
CVO91_RS12425	COG2182	Extracellular solute-binding protein
CVO91_RS12430	COG1175	transmembrane transport
CVO91_RS12435	COG3833	ABC-type maltose transport systems, permease component
CVO91_RS12440	COG5521	maltodextrose utilization protein MalA
CVO91_RS12445	COG1609	Transcriptional regulator
CVO91_RS12450	COG1523	belongs to the glycosyl hydrolase 13 family
CVO91_RS12455	COG1780	Probably involved in ribonucleotide reductase function
CVO91_RS12460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CVO91_RS12465	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CVO91_RS12470	COG2153	protein acetylation
CVO91_RS12475	COG4989	oxidoreductase activity
CVO91_RS12480	COG1216	Glycosyl transferase, family 2
CVO91_RS12500	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CVO91_RS12510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CVO91_RS12515	COG0785	Cytochrome C biogenesis protein
CVO91_RS12525	COG0305	Participates in initiation and elongation during chromosome replication
CVO91_RS12530	COG0359	binds to the 23S rRNA
CVO91_RS12540	COG0445	tRNA wobble uridine modification
CVO91_RS12555	COG1051	belongs to the nudix hydrolase family
CVO91_RS12570	COG1733	regulation of RNA biosynthetic process
CVO91_RS12580	COG0482	sulfurtransferase activity
CVO91_RS12585	COG1760	l-serine dehydratase
CVO91_RS12590	COG1760	l-serine dehydratase
CVO91_RS12600	COG0745	RESPONSE REGULATOR receiver
CVO91_RS12605	COG5002	protein histidine kinase activity
CVO91_RS12605	COG3850	Histidine kinase
CVO91_RS12615	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CVO91_RS12620	COG1122	ATPase activity
CVO91_RS12625	COG1122	ATPase activity
CVO91_RS12630	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CVO91_RS12635	COG1426	Protein conserved in bacteria
CVO91_RS12640	COG0612	Peptidase, M16
CVO91_RS12645	COG0612	Peptidase, M16
CVO91_RS12655	COG1724	mRNA binding
CVO91_RS12730	COG0582	viral genome integration into host DNA
CVO91_RS12740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CVO91_RS12745	COG0516	GMP reductase activity
CVO91_RS12745	COG0517	IMP dehydrogenase activity
CVO91_RS12755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CVO91_RS12760	COG0488	(ABC) transporter
CVO91_RS12805	COG2910	NAD(P)H-binding
CVO91_RS12815	COG4372	Transposase
CVO91_RS12870	COG4372	Transposase
CVO91_RS12900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CVO91_RS12905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CVO91_RS12910	COG1475	DNA binding