locus-tag	class	description
H7677_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7677_RS00010	COG0592	DNA-directed DNA polymerase activity
H7677_RS00030	COG0012	GTP binding
H7677_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
H7677_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7677_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7677_RS00060	COG0037	tRNA processing
H7677_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7677_RS00180	COG1792	Involved in formation and maintenance of cell shape
H7677_RS00195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7677_RS00200	COG0436	Aminotransferase
H7677_RS00205	COG1381	Involved in DNA repair and RecF pathway recombination
H7677_RS00210	COG0416	fatty acid biosynthetic process
H7677_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7677_RS00225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7677_RS00240	COG0138	bifunctional purine biosynthesis protein purh
H7677_RS00250	COG0151	Belongs to the GarS family
H7677_RS00255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7677_RS00260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7677_RS00270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7677_RS00310	COG1131	(ABC) transporter
H7677_RS00320	COG1132	(ABC) transporter
H7677_RS00330	COG2255	four-way junction helicase activity
H7677_RS00335	COG0546	phosphoglycolate phosphatase activity
H7677_RS00345	COG0285	dihydrofolate synthase activity
H7677_RS00355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7677_RS00360	COG0632	four-way junction helicase activity
H7677_RS00365	COG2818	Glycosylase
H7677_RS00370	COG1396	sequence-specific DNA binding
H7677_RS00385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H7677_RS00390	COG1393	Belongs to the ArsC family
H7677_RS00395	COG4472	Bacterial protein of unknown function (DUF965)
H7677_RS00400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7677_RS00405	COG3906	Belongs to the UPF0473 family
H7677_RS00420	COG0051	transcription antitermination factor activity, RNA binding
H7677_RS00425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7677_RS00430	COG0088	Forms part of the polypeptide exit tunnel
H7677_RS00435	COG0089	rRNA binding
H7677_RS00440	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7677_RS00445	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H7677_RS00450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H7677_RS00455	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H7677_RS00460	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H7677_RS00465	COG0255	Belongs to the universal ribosomal protein uL29 family
H7677_RS00470	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H7677_RS00475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H7677_RS00480	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H7677_RS00485	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H7677_RS00490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7677_RS00495	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H7677_RS00500	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H7677_RS00505	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H7677_RS00510	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H7677_RS00515	COG1841	ribosomal large subunit assembly
H7677_RS00525	COG0201	protein transport
H7677_RS00530	COG0563	adenylate kinase activity
H7677_RS00535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H7677_RS00540	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7677_RS00545	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H7677_RS00555	COG0202	RNA polymerase activity
H7677_RS00660	COG1121	(ABC) transporter
H7677_RS00665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7677_RS00670	COG3443	Belongs to the bacterial solute-binding protein 9 family
H7677_RS00670	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7677_RS00700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7677_RS00705	COG0085	RNA polymerase activity
H7677_RS00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H7677_RS00720	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7677_RS00725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7677_RS00730	COG1459	type II secretion system
H7677_RS00735	COG4537	Required for transformation and DNA binding
H7677_RS00765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7677_RS00775	COG0285	dihydrofolate synthase activity
H7677_RS00780	COG1363	Peptidase, m42
H7677_RS00790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7677_RS00800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7677_RS00825	COG0459	protein refolding
H7677_RS00835	COG0049	tRNA binding
H7677_RS00840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7677_RS00845	COG3590	peptidase
H7677_RS00855	COG0126	phosphoglycerate kinase activity
H7677_RS00865	COG0789	Transcriptional regulator
H7677_RS00870	COG0174	glutamine synthetase
H7677_RS00885	COG1214	PFAM Peptidase M22, glycoprotease
H7677_RS00895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H7677_RS00900	COG2207	Transcriptional regulator
H7677_RS00910	COG1175	transmembrane transport
H7677_RS00915	COG0395	ABC-type sugar transport system, permease component
H7677_RS00935	COG2855	membrane
H7677_RS00950	COG1131	(ABC) transporter
H7677_RS00955	COG2081	HI0933 family
H7677_RS00960	COG2723	6-phospho-beta-galactosidase activity
H7677_RS00975	COG0584	glycerophosphoryl diester phosphodiesterase
H7677_RS00980	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H7677_RS00985	COG2222	sugar isomerase
H7677_RS01005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7677_RS01010	COG1882	Formate acetyltransferase
H7677_RS01025	COG2910	NAD(P)H-binding
H7677_RS01040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7677_RS01045	COG0681	Belongs to the peptidase S26 family
H7677_RS01065	COG0366	Alpha amylase catalytic
H7677_RS01070	COG1263	PTS System
H7677_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7677_RS01075	COG2188	Transcriptional regulator
H7677_RS01090	COG1193	negative regulation of DNA recombination
H7677_RS01100	COG3118	belongs to the thioredoxin family
H7677_RS01105	COG0318	PFAM AMP-dependent synthetase and ligase
H7677_RS01110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7677_RS01110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7677_RS01125	COG1115	amino acid carrier protein
H7677_RS01130	COG0668	transmembrane transport
H7677_RS01140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7677_RS01145	COG0167	dihydroorotate dehydrogenase activity
H7677_RS01150	COG2843	Capsule synthesis protein
H7677_RS01155	COG0561	phosphatase activity
H7677_RS01170	COG1131	(ABC) transporter
H7677_RS01175	COG1309	transcriptional regulator
H7677_RS01180	COG1511	domain protein
H7677_RS01205	COG1346	cytolysis
H7677_RS01210	COG2116	formate transmembrane transporter activity
H7677_RS01215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7677_RS01220	COG0433	COG0433 Predicted ATPase
H7677_RS01245	COG0582	viral genome integration into host DNA
H7677_RS01265	COG1674	ftsk spoiiie
H7677_RS01300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7677_RS01305	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H7677_RS01310	COG0124	histidyl-tRNA synthetase
H7677_RS01315	COG1064	alcohol dehydrogenase
H7677_RS01320	COG1012	belongs to the aldehyde dehydrogenase family
H7677_RS01320	COG1454	alcohol dehydrogenase
H7677_RS01360	COG4988	ABC transporter
H7677_RS01365	COG1132	(ABC) transporter
H7677_RS01380	COG1129	ABC transporter
H7677_RS01385	COG0534	Mate efflux family protein
H7677_RS01390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H7677_RS01405	COG1304	FMN binding
H7677_RS01410	COG1132	(ABC) transporter
H7677_RS01415	COG1132	(ABC) transporter
H7677_RS01420	COG3830	Belongs to the UPF0237 family
H7677_RS01425	COG2848	UPF0210 protein
H7677_RS01430	COG0588	phosphoglycerate mutase activity
H7677_RS01450	COG1420	regulation of RNA biosynthetic process
H7677_RS01455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7677_RS01460	COG0443	Heat shock 70 kDa protein
H7677_RS01465	COG0484	heat shock protein binding
H7677_RS01470	COG0095	Lipoate-protein ligase
H7677_RS01480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7677_RS01510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7677_RS01515	COG0765	amino acid transport
H7677_RS01520	COG3655	Transcriptional regulator
H7677_RS01530	COG2217	Heavy metal translocating P-type atpase
H7677_RS01555	COG4475	Protein of unknown function (DUF436)
H7677_RS01580	COG4221	oxidoreductase activity
H7677_RS01585	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7677_RS01585	COG1902	pentaerythritol trinitrate reductase activity
H7677_RS01605	COG0544	peptidyl-prolyl cis-trans isomerase activity
H7677_RS01615	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7677_RS01625	COG3343	RNA polymerase activity
H7677_RS01630	COG0504	CTP synthase activity
H7677_RS01640	COG0191	fructose-bisphosphate aldolase activity
H7677_RS01645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H7677_RS01680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7677_RS01705	COG0589	response to stress
H7677_RS01710	COG0436	Aminotransferase
H7677_RS01715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7677_RS01720	COG1335	isochorismatase
H7677_RS01725	COG0335	large ribosomal subunit rRNA binding
H7677_RS01735	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7677_RS01740	COG0154	amidase activity
H7677_RS01745	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7677_RS01750	COG1609	Transcriptional regulator
H7677_RS01755	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H7677_RS01760	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H7677_RS01770	COG3142	Participates in the control of copper homeostasis
H7677_RS01785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7677_RS01790	COG1534	Rna-binding protein
H7677_RS01795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H7677_RS01800	COG1713	HD superfamily hydrolase involved in NAD metabolism
H7677_RS01815	COG1335	isochorismatase
H7677_RS01820	COG0799	negative regulation of ribosome biogenesis
H7677_RS01825	COG2226	methyltransferase
H7677_RS01845	COG0789	Transcriptional regulator
H7677_RS01855	COG0242	peptide deformylase activity
H7677_RS01865	COG1640	4-alpha-glucanotransferase
H7677_RS01870	COG0058	SHG alpha-glucan phosphorylase activity
H7677_RS01885	COG2190	(PTS) system
H7677_RS01885	COG1263	PTS System
H7677_RS01885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7677_RS01900	COG0217	transcriptional regulatory protein
H7677_RS01910	COG4720	Psort location CytoplasmicMembrane, score
H7677_RS01920	COG1054	Belongs to the UPF0176 family
H7677_RS01930	COG1122	ATPase activity
H7677_RS01945	COG0357	Ribosomal RNA small subunit methyltransferase G
H7677_RS01950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7677_RS01955	COG3331	DNA recombination
H7677_RS01960	COG4474	Belongs to the UPF0398 family
H7677_RS01965	COG3599	regulation of cell shape
H7677_RS01975	COG0116	Belongs to the methyltransferase superfamily
H7677_RS01985	COG1854	S-ribosylhomocysteine lyase activity
H7677_RS01990	COG1418	mRNA catabolic process
H7677_RS02000	COG1758	RNA polymerase activity
H7677_RS02005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7677_RS02010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7677_RS02015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7677_RS02015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7677_RS02020	COG0631	protein serine/threonine phosphatase activity
H7677_RS02025	COG2815	serine threonine protein kinase
H7677_RS02025	COG0515	serine threonine protein kinase
H7677_RS02050	COG1098	S1 RNA binding domain
H7677_RS02060	COG1739	Uncharacterized protein family UPF0029
H7677_RS02065	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H7677_RS02150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7677_RS02160	COG3557	Belongs to the UPF0374 family
H7677_RS02170	COG2188	Transcriptional regulator
H7677_RS02175	COG2188	Transcriptional regulator
H7677_RS02185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7677_RS02195	COG3716	PTS system mannose fructose sorbose family IID component
H7677_RS02205	COG2017	converts alpha-aldose to the beta-anomer
H7677_RS02275	COG1217	gtp-binding protein TYPA
H7677_RS02290	COG0681	Belongs to the peptidase S26 family
H7677_RS02295	COG4886	Leucine-rich repeat (LRR) protein
H7677_RS02320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7677_RS02335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7677_RS02340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H7677_RS02345	COG1799	cell septum assembly
H7677_RS02360	COG3599	regulation of cell shape
H7677_RS02380	COG0406	alpha-ribazole phosphatase activity
H7677_RS02380	COG0494	nUDIX hydrolase
H7677_RS02385	COG0542	response to heat
H7677_RS02390	COG4703	Protein of unknown function (DUF1797)
H7677_RS02395	COG0765	amino acid transport
H7677_RS02405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H7677_RS02435	COG0789	Transcriptional regulator
H7677_RS02450	COG0826	peptidase U32
H7677_RS02460	COG4443	Transcriptional Coactivator p15 (PC4)
H7677_RS02465	COG1268	BioY protein
H7677_RS02470	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H7677_RS02475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7677_RS02480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7677_RS02485	COG1136	(ABC) transporter
H7677_RS02490	COG0577	efflux transmembrane transporter activity
H7677_RS02500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H7677_RS02510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7677_RS02520	COG3859	Proton-coupled thiamine transporter YuaJ
H7677_RS02540	COG0772	Belongs to the SEDS family
H7677_RS02545	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H7677_RS02565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7677_RS02570	COG0149	triose-phosphate isomerase activity
H7677_RS02580	COG1078	dGTPase activity
H7677_RS02615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7677_RS02625	COG2884	Cell division ATP-binding protein ftsE
H7677_RS02630	COG2177	Part of the ABC transporter FtsEX involved in
H7677_RS02660	COG4974	Belongs to the 'phage' integrase family
H7677_RS02785	COG0582	viral genome integration into host DNA
H7677_RS02825	COG1484	DNA-dependent DNA replication
H7677_RS02835	COG0305	Participates in initiation and elongation during chromosome replication
H7677_RS02905	COG0582	viral genome integration into host DNA
H7677_RS02925	COG1132	(ABC) transporter
H7677_RS02930	COG1132	(ABC) transporter
H7677_RS02935	COG1011	Hydrolase
H7677_RS02955	COG1737	Transcriptional regulator
H7677_RS02975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7677_RS02980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7677_RS02985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H7677_RS02995	COG2814	Major facilitator Superfamily
H7677_RS03000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7677_RS03010	COG0557	exoribonuclease II activity
H7677_RS03015	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H7677_RS03020	COG1063	alcohol dehydrogenase
H7677_RS03035	COG2217	Heavy metal translocating P-type atpase
H7677_RS03040	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H7677_RS03050	COG1136	(ABC) transporter
H7677_RS03065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7677_RS03065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7677_RS03075	COG1832	CoA-binding protein
H7677_RS03085	COG0343	queuine tRNA-ribosyltransferase activity
H7677_RS03095	COG1609	Transcriptional regulator
H7677_RS03110	COG0438	transferase activity, transferring glycosyl groups
H7677_RS03125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7677_RS03130	COG0765	amino acid transport
H7677_RS03135	COG0765	amino acid transport
H7677_RS03140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7677_RS03150	COG0745	RESPONSE REGULATOR receiver
H7677_RS03160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H7677_RS03190	COG0768	penicillin binding
H7677_RS03195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7677_RS03200	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7677_RS03210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7677_RS03220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7677_RS03230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7677_RS03250	COG1609	Transcriptional regulator
H7677_RS03255	COG4209	transmembrane transport
H7677_RS03260	COG0395	ABC-type sugar transport system, permease component
H7677_RS03270	COG1621	beta-fructofuranosidase activity
H7677_RS03275	COG0697	spore germination
H7677_RS03275	COG1674	ftsk spoiiie
H7677_RS03280	COG0346	lactoylglutathione lyase activity
H7677_RS03305	COG0625	glutathione transferase activity
H7677_RS03310	COG2244	polysaccharide biosynthetic process
H7677_RS03315	COG0528	UMP kinase activity
H7677_RS03320	COG0233	cytoplasmic translational termination
H7677_RS03325	COG2996	Protein conserved in bacteria
H7677_RS03340	COG4479	Belongs to the UPF0346 family
H7677_RS03345	COG1702	phosphate starvation-inducible protein PhoH
H7677_RS03350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7677_RS03355	COG2807	transmembrane transport
H7677_RS03365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H7677_RS03370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7677_RS03380	COG1234	tRNA 3'-trailer cleavage
H7677_RS03385	COG0300	oxidoreductase activity
H7677_RS03395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7677_RS03400	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H7677_RS03400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7677_RS03410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7677_RS03425	COG2384	SAM-dependent methyltransferase
H7677_RS03430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7677_RS03440	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H7677_RS03455	COG1088	dTDP-glucose 4,6-dehydratase activity
H7677_RS03460	COG1091	dTDP-4-dehydrorhamnose reductase activity
H7677_RS03490	COG0463	Glycosyl transferase, family 2
H7677_RS03520	COG1442	glycosyl transferase family 8
H7677_RS03525	COG1442	glycosyl transferase family 8
H7677_RS03525	COG1216	Glycosyl transferase, family 2
H7677_RS03540	COG1216	Glycosyl transferase, family 2
H7677_RS03570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H7677_RS03580	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7677_RS03595	COG1368	sulfuric ester hydrolase activity
H7677_RS03600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H7677_RS03605	COG0710	3-dehydroquinate dehydratase activity
H7677_RS03610	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H7677_RS03615	COG0287	Prephenate dehydrogenase
H7677_RS03620	COG3679	Belongs to the UPF0342 family
H7677_RS03630	COG3684	Belongs to the aldolase LacD family
H7677_RS03645	COG4120	Belongs to the binding-protein-dependent transport system permease family
H7677_RS03650	COG1116	anion transmembrane transporter activity
H7677_RS03650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7677_RS03655	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H7677_RS03660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7677_RS03665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7677_RS03670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7677_RS03680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7677_RS03680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7677_RS03705	COG4122	O-methyltransferase activity
H7677_RS03710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7677_RS03720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7677_RS03745	COG1476	TRANSCRIPTIONal
H7677_RS03785	COG1028	Short-chain dehydrogenase reductase Sdr
H7677_RS03810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7677_RS03815	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7677_RS03825	COG3716	PTS system mannose fructose sorbose family IID component
H7677_RS03835	COG5492	domain, Protein
H7677_RS03845	COG1609	Transcriptional regulator
H7677_RS03850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7677_RS03855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7677_RS03860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H7677_RS03865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7677_RS03870	COG0372	Belongs to the citrate synthase family
H7677_RS03875	COG0538	isocitrate dehydrogenase activity
H7677_RS03880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7677_RS03915	COG1196	nuclear chromosome segregation
H7677_RS03920	COG0561	phosphatase activity
H7677_RS03925	COG0561	phosphatase activity
H7677_RS03930	COG0552	protein localization to endoplasmic reticulum
H7677_RS03945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H7677_RS03950	COG3689	TIGRFAM TIGR03943 family protein
H7677_RS03955	COG0701	Predicted permease
H7677_RS03970	COG1597	lipid kinase activity
H7677_RS03980	COG0356	it plays a direct role in the translocation of protons across the membrane
H7677_RS03985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H7677_RS03990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7677_RS03995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H7677_RS04000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H7677_RS04005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7677_RS04010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H7677_RS04020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7677_RS04035	COG2211	Major facilitator Superfamily
H7677_RS04045	COG3250	beta-galactosidase activity
H7677_RS04055	COG0800	Aldolase
H7677_RS04065	COG1312	Catalyzes the dehydration of D-mannonate
H7677_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
H7677_RS04100	COG0072	phenylalanine-tRNA ligase activity
H7677_RS04100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7677_RS04125	COG1051	belongs to the nudix hydrolase family
H7677_RS04130	COG0302	gtp cyclohydrolase
H7677_RS04150	COG2610	gluconate transmembrane transporter activity
H7677_RS04155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7677_RS04170	COG1846	Transcriptional regulator
H7677_RS04175	COG3759	membrane
H7677_RS04190	COG1695	Transcriptional regulator
H7677_RS04205	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7677_RS04210	COG0561	phosphatase activity
H7677_RS04250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7677_RS04255	COG0196	riboflavin kinase activity
H7677_RS04260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7677_RS04265	COG1393	Belongs to the ArsC family
H7677_RS04270	COG4476	Belongs to the UPF0223 family
H7677_RS04275	COG0483	inositol monophosphate 1-phosphatase activity
H7677_RS04280	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
H7677_RS04280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7677_RS04290	COG0573	inorganic phosphate transmembrane transporter activity
H7677_RS04295	COG0581	inorganic phosphate transmembrane transporter activity
H7677_RS04300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7677_RS04305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7677_RS04310	COG0704	Plays a role in the regulation of phosphate uptake
H7677_RS04320	COG0745	RESPONSE REGULATOR receiver
H7677_RS04325	COG5002	protein histidine kinase activity
H7677_RS04335	COG0268	Binds directly to 16S ribosomal RNA
H7677_RS04340	COG1072	(Pantothenic acid kinase))
H7677_RS04345	COG2813	Specifically methylates the guanine in position
H7677_RS04350	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H7677_RS04365	COG1744	ABC transporter substrate-binding protein PnrA-like
H7677_RS04370	COG3845	ABC transporter
H7677_RS04375	COG4603	Belongs to the binding-protein-dependent transport system permease family
H7677_RS04380	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7677_RS04390	COG0039	L-malate dehydrogenase activity
H7677_RS04395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7677_RS04400	COG3764	Sortase (surface protein transpeptidase)
H7677_RS04410	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H7677_RS04415	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H7677_RS04430	COG1104	cysteine desulfurase activity
H7677_RS04440	COG4116	CYTH
H7677_RS04445	COG2357	RelA SpoT domain protein
H7677_RS04450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7677_RS04455	COG0564	pseudouridine synthase activity
H7677_RS04460	COG0280	phosphate acetyltransferase
H7677_RS04465	COG1132	(ABC) transporter
H7677_RS04470	COG1132	(ABC) transporter
H7677_RS04480	COG1194	a g-specific adenine glycosylase
H7677_RS04485	COG1396	sequence-specific DNA binding
H7677_RS04510	COG1349	DNA-binding transcription factor activity
H7677_RS04515	COG0698	ribose 5-phosphate isomerase
H7677_RS04520	COG0698	ribose 5-phosphate isomerase
H7677_RS04525	COG1105	Belongs to the carbohydrate kinase PfkB family
H7677_RS04530	COG3684	Belongs to the aldolase LacD family
H7677_RS04535	COG3711	transcriptional antiterminator
H7677_RS04545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7677_RS04545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7677_RS04575	COG2873	o-acetylhomoserine
H7677_RS04580	COG0488	(ABC) transporter
H7677_RS04590	COG1126	abc transporter atp-binding protein
H7677_RS04615	COG3583	domain protein
H7677_RS04635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7677_RS04645	COG0297	glycogen (starch) synthase activity
H7677_RS04670	COG0167	dihydroorotate dehydrogenase activity
H7677_RS04675	COG0284	orotidine-5'-phosphate decarboxylase activity
H7677_RS04680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H7677_RS04690	COG0463	Glycosyl transferase, family 2
H7677_RS04695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7677_RS04705	COG0737	Belongs to the 5'-nucleotidase family
H7677_RS04710	COG0424	maF-like protein
H7677_RS04720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7677_RS04725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7677_RS04735	COG1272	protein, Hemolysin III
H7677_RS04745	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7677_RS04750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7677_RS04755	COG1937	Protein conserved in bacteria
H7677_RS04760	COG0110	maltose O-acetyltransferase activity
H7677_RS04765	COG0758	DNA mediated transformation
H7677_RS04770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7677_RS04775	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H7677_RS04780	COG0222	ribosome binding
H7677_RS04795	COG0270	DNA (cytosine-5-)-methyltransferase activity
H7677_RS04930	COG1475	DNA binding
H7677_RS04935	COG4443	Transcriptional Coactivator p15 (PC4)
H7677_RS04990	COG1396	sequence-specific DNA binding
H7677_RS04995	COG0542	response to heat
H7677_RS05000	COG0613	PHP domain protein
H7677_RS05040	COG4974	Belongs to the 'phage' integrase family
H7677_RS05045	COG0647	UMP catabolic process
H7677_RS05050	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H7677_RS05055	COG2207	Transcriptional regulator
H7677_RS05055	COG3708	Transcriptional regulator
H7677_RS05100	COG1136	(ABC) transporter
H7677_RS05105	COG0577	efflux transmembrane transporter activity
H7677_RS05120	COG0745	RESPONSE REGULATOR receiver
H7677_RS05135	COG4974	Belongs to the 'phage' integrase family
H7677_RS05155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7677_RS05160	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H7677_RS05165	COG2188	Transcriptional regulator
H7677_RS05175	COG4268	DNA restriction-modification system
H7677_RS05180	COG1401	restriction endodeoxyribonuclease activity
H7677_RS05205	COG4221	oxidoreductase activity
H7677_RS05210	COG0741	lytic transglycosylase activity
H7677_RS05220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H7677_RS05230	COG0009	L-threonylcarbamoyladenylate synthase
H7677_RS05235	COG2890	protein-(glutamine-N5) methyltransferase activity
H7677_RS05240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H7677_RS05265	COG0481	GTPase activity
H7677_RS05280	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H7677_RS05285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7677_RS05290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H7677_RS05300	COG1940	carbohydrate kinase activity
H7677_RS05310	COG0488	(ABC) transporter
H7677_RS05315	COG0617	tRNA 3'-terminal CCA addition
H7677_RS05320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H7677_RS05325	COG1307	EDD domain protein, DegV family
H7677_RS05335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7677_RS05335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7677_RS05335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7677_RS05340	COG1105	Belongs to the carbohydrate kinase PfkB family
H7677_RS05345	COG1349	DNA-binding transcription factor activity
H7677_RS05350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7677_RS05355	COG0336	Belongs to the RNA methyltransferase TrmD family
H7677_RS05360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7677_RS05365	COG0534	Mate efflux family protein
H7677_RS05375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7677_RS05380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7677_RS05395	COG0038	chloride channel
H7677_RS05405	COG1177	transmembrane transport
H7677_RS05410	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7677_RS05415	COG3842	ATPase activity
H7677_RS05420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H7677_RS05425	COG0083	homoserine kinase activity
H7677_RS05430	COG0460	homoserine dehydrogenase
H7677_RS05435	COG0726	polysaccharide deacetylase
H7677_RS05440	COG1132	(ABC) transporter
H7677_RS05455	COG0228	four-way junction DNA binding
H7677_RS05465	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H7677_RS05470	COG2136	Putative SAM-dependent methyltransferase
H7677_RS05470	COG2521	methyltransferase
H7677_RS05480	COG0505	Belongs to the CarA family
H7677_RS05485	COG0540	Belongs to the ATCase OTCase family
H7677_RS05490	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H7677_RS05500	COG2824	Alkylphosphonate utilization operon protein PhnA
H7677_RS05505	COG0564	pseudouridine synthase activity
H7677_RS05525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H7677_RS05530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H7677_RS05535	COG1114	Component of the transport system for branched-chain amino acids
H7677_RS05540	COG0301	tRNA thio-modification
H7677_RS05545	COG1104	cysteine desulfurase activity
H7677_RS05570	COG0539	negative regulation of cytoplasmic translation
H7677_RS05590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7677_RS05600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7677_RS05610	COG2184	nucleotidyltransferase activity
H7677_RS05620	COG0187	DNA topoisomerase II activity
H7677_RS05630	COG1074	ATP-dependent DNA helicase activity
H7677_RS05635	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H7677_RS05665	COG1131	(ABC) transporter
H7677_RS05695	COG1011	Hydrolase
H7677_RS05795	COG3209	COG3209 Rhs family protein
H7677_RS05810	COG4509	Sortase family
H7677_RS05820	COG0210	DNA helicase
H7677_RS05835	COG1164	Oligoendopeptidase f
H7677_RS05845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7677_RS05850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7677_RS05870	COG1882	Formate acetyltransferase
H7677_RS05875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7677_RS05880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7677_RS05885	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7677_RS05895	COG1349	DNA-binding transcription factor activity
H7677_RS05900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H7677_RS05940	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H7677_RS05950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7677_RS05955	COG4684	Psort location CytoplasmicMembrane, score
H7677_RS05960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7677_RS05985	COG0531	amino acid
H7677_RS05995	COG0708	Exodeoxyribonuclease III
H7677_RS06005	COG1393	Belongs to the ArsC family
H7677_RS06015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7677_RS06025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H7677_RS06035	COG4467	Involved in initiation control of chromosome replication
H7677_RS06040	COG0470	DNA polymerase III
H7677_RS06045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H7677_RS06050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7677_RS06065	COG0517	IMP dehydrogenase activity
H7677_RS06075	COG2333	competence protein COMEC
H7677_RS06075	COG0658	competence protein
H7677_RS06080	COG1555	photosystem II stabilization
H7677_RS06080	COG1596	polysaccharide export
H7677_RS06085	COG0204	Acyl-transferase
H7677_RS06090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7677_RS06095	COG1120	ATPase activity
H7677_RS06100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7677_RS06105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7677_RS06110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7677_RS06115	COG0386	Belongs to the glutathione peroxidase family
H7677_RS06120	COG1187	pseudouridine synthase activity
H7677_RS06125	COG0435	Glutathione S-transferase
H7677_RS06135	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H7677_RS06140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7677_RS06145	COG1696	Membrane protein involved in D-alanine export
H7677_RS06180	COG0363	glucosamine-6-phosphate deaminase activity
H7677_RS06185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H7677_RS06190	COG1438	arginine binding
H7677_RS06195	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H7677_RS06195	COG3064	Membrane
H7677_RS06195	COG3583	domain protein
H7677_RS06200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7677_RS06205	COG1288	antiporter activity
H7677_RS06210	COG0549	Belongs to the carbamate kinase family
H7677_RS06215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7677_RS06220	COG0454	-acetyltransferase
H7677_RS06235	COG1481	regulation of sporulation
H7677_RS06240	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H7677_RS06245	COG1660	Displays ATPase and GTPase activities
H7677_RS06250	COG0251	oxidation-reduction process
H7677_RS06255	COG0534	Mate efflux family protein
H7677_RS06265	COG0436	Aminotransferase
H7677_RS06280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7677_RS06285	COG0562	UDP-galactopyranose mutase
H7677_RS06295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7677_RS06305	COG0077	Prephenate dehydratase
H7677_RS06310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7677_RS06325	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7677_RS06350	COG1086	Polysaccharide biosynthesis protein
H7677_RS06375	COG0438	transferase activity, transferring glycosyl groups
H7677_RS06380	COG0110	maltose O-acetyltransferase activity
H7677_RS06395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7677_RS06405	COG4464	protein tyrosine phosphatase activity
H7677_RS06415	COG3944	biosynthesis protein
H7677_RS06420	COG1316	TRANSCRIPTIONal
H7677_RS06425	COG3022	response to hydroperoxide
H7677_RS06430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7677_RS06445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7677_RS06450	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7677_RS06455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7677_RS06475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7677_RS06480	COG1126	abc transporter atp-binding protein
H7677_RS06485	COG0765	amino acid transport
H7677_RS06490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7677_RS06500	COG0657	acetylesterase activity
H7677_RS06500	COG2755	lipolytic protein G-D-S-L family
H7677_RS06505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7677_RS06515	COG0469	pyruvate kinase activity
H7677_RS06520	COG0205	6-phosphofructokinase activity
H7677_RS06530	COG2188	Transcriptional regulator
H7677_RS06535	COG1131	(ABC) transporter
H7677_RS06545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H7677_RS06570	COG5433	transposase activity
H7677_RS06590	COG2151	metal-sulfur cluster biosynthetic enzyme
H7677_RS06595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7677_RS06600	COG0358	DNA primase activity
H7677_RS06605	COG1970	mechanosensitive ion channel activity
H7677_RS06610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7677_RS06615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H7677_RS06625	COG0647	UMP catabolic process
H7677_RS06630	COG1051	belongs to the nudix hydrolase family
H7677_RS06640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7677_RS06650	COG0058	SHG alpha-glucan phosphorylase activity
H7677_RS06655	COG0813	purine-nucleoside phosphorylase activity
H7677_RS06660	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H7677_RS06670	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H7677_RS06675	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H7677_RS06685	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
H7677_RS06690	COG1518	maintenance of DNA repeat elements
H7677_RS06700	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7677_RS06715	COG2268	Band 7 protein
H7677_RS06720	COG1704	LemA family
H7677_RS06730	COG1573	uracil-dna glycosylase
H7677_RS06750	COG2226	methyltransferase
H7677_RS06755	COG0488	(ABC) transporter
H7677_RS06760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7677_RS06775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7677_RS06780	COG3442	glutamine amidotransferase
H7677_RS06785	COG2226	methyltransferase
H7677_RS06795	COG0488	(ABC) transporter
H7677_RS06830	COG3842	ATPase activity
H7677_RS06850	COG2190	(PTS) system
H7677_RS06850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7677_RS06850	COG1263	PTS System
H7677_RS06855	COG3711	transcriptional antiterminator
H7677_RS06860	COG1293	RNA-binding protein homologous to eukaryotic snRNP
H7677_RS06865	COG3527	Alpha-acetolactate decarboxylase
H7677_RS06875	COG0628	permease
H7677_RS06880	COG2706	6-phosphogluconolactonase activity
H7677_RS06890	COG1011	Hydrolase
H7677_RS06925	COG0560	Phosphoserine phosphatase
H7677_RS06930	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
H7677_RS06935	COG0187	DNA topoisomerase II activity
H7677_RS06940	COG0693	protein deglycase activity
H7677_RS06945	COG0772	Belongs to the SEDS family
H7677_RS06960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7677_RS06965	COG0716	FMN binding
H7677_RS06975	COG0287	Prephenate dehydrogenase
H7677_RS06975	COG1605	Chorismate mutase
H7677_RS06980	COG0038	chloride channel
H7677_RS06990	COG0737	Belongs to the 5'-nucleotidase family
H7677_RS06995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7677_RS07000	COG1466	dna polymerase III delta subunit
H7677_RS07035	COG0683	leucine binding
H7677_RS07050	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H7677_RS07055	COG0366	Alpha amylase catalytic
H7677_RS07060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H7677_RS07065	COG0626	cystathionine gamma-synthase activity
H7677_RS07080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H7677_RS07085	COG2827	Endonuclease containing a URI domain
H7677_RS07105	COG0640	Transcriptional regulator
H7677_RS07110	COG0513	Belongs to the DEAD box helicase family
H7677_RS07115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7677_RS07155	COG0494	nUDIX hydrolase
H7677_RS07160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7677_RS07170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7677_RS07175	COG1028	Short-chain dehydrogenase reductase Sdr
H7677_RS07200	COG0577	efflux transmembrane transporter activity
H7677_RS07205	COG1136	(ABC) transporter
H7677_RS07210	COG2205	protein histidine kinase activity
H7677_RS07225	COG0436	Aminotransferase
H7677_RS07255	COG1174	glycine betaine transport
H7677_RS07260	COG0517	IMP dehydrogenase activity
H7677_RS07260	COG1125	glycine betaine transport
H7677_RS07280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H7677_RS07285	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H7677_RS07290	COG1482	cell wall glycoprotein biosynthetic process
H7677_RS07305	COG3091	SprT-like family
H7677_RS07310	COG2183	response to ionizing radiation
H7677_RS07315	COG0656	L-ascorbic acid biosynthetic process
H7677_RS07320	COG4708	membrane
H7677_RS07325	COG2246	polysaccharide biosynthetic process
H7677_RS07335	COG0024	Methionine aminopeptidase
H7677_RS07345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7677_RS07360	COG2207	Transcriptional regulator
H7677_RS07365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H7677_RS07370	COG2131	deaminase
H7677_RS07380	COG1363	Peptidase, m42
H7677_RS07395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7677_RS07400	COG1956	GAF domain-containing protein
H7677_RS07410	COG1695	Transcriptional regulator
H7677_RS07420	COG0673	inositol 2-dehydrogenase activity
H7677_RS07425	COG0513	Belongs to the DEAD box helicase family
H7677_RS07430	COG0726	polysaccharide deacetylase
H7677_RS07450	COG0183	Belongs to the thiolase family
H7677_RS07455	COG3425	synthase
H7677_RS07475	COG0776	regulation of translation
H7677_RS07485	COG2755	lipolytic protein G-D-S-L family
H7677_RS07490	COG1307	EDD domain protein, DegV family
H7677_RS07495	COG0497	DNA recombination
H7677_RS07500	COG1438	arginine binding
H7677_RS07505	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H7677_RS07515	COG1722	exodeoxyribonuclease VII activity
H7677_RS07520	COG1570	exodeoxyribonuclease VII activity
H7677_RS07525	COG2321	neutral zinc metallopeptidase
H7677_RS07530	COG1755	Isoprenylcysteine carboxyl methyltransferase
H7677_RS07535	COG5002	protein histidine kinase activity
H7677_RS07540	COG0745	RESPONSE REGULATOR receiver
H7677_RS07565	COG1227	inorganic diphosphatase activity
H7677_RS07575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H7677_RS07580	COG1253	flavin adenine dinucleotide binding
H7677_RS07585	COG1119	ATPase activity
H7677_RS07590	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H7677_RS07610	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H7677_RS07615	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7677_RS07630	COG4470	Protein conserved in bacteria
H7677_RS07635	COG3480	Lon protease (S16) C-terminal proteolytic domain
H7677_RS07640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7677_RS07645	COG0742	ribosomal rna small subunit methyltransferase
H7677_RS07655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7677_RS07660	COG4483	Protein conserved in bacteria
H7677_RS07665	COG2197	response regulator
H7677_RS07670	COG4585	Histidine kinase
H7677_RS07675	COG0842	Transport permease protein
H7677_RS07680	COG1131	(ABC) transporter
H7677_RS07695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7677_RS07710	COG0671	phosphoesterase, PA-phosphatase related
H7677_RS07715	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H7677_RS07725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7677_RS07730	COG1187	pseudouridine synthase activity
H7677_RS07735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7677_RS07740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H7677_RS07745	COG0582	viral genome integration into host DNA
H7677_RS07765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7677_RS07770	COG3763	UPF0154 protein
H7677_RS07780	COG3579	cysteine-type endopeptidase activity
H7677_RS07795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7677_RS07800	COG1254	Belongs to the acylphosphatase family
H7677_RS07810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7677_RS07815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7677_RS07825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7677_RS07835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7677_RS07845	COG1160	GTP binding
H7677_RS07855	COG1484	DNA-dependent DNA replication
H7677_RS07865	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7677_RS07870	COG0628	permease
H7677_RS07880	COG0745	RESPONSE REGULATOR receiver
H7677_RS07885	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7677_RS07895	COG0492	ferredoxin-NADP+ reductase activity
H7677_RS07905	COG0513	Belongs to the DEAD box helicase family
H7677_RS07920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7677_RS07925	COG0768	penicillin binding
H7677_RS07935	COG0275	rRNA processing
H7677_RS07980	COG4939	FMN-binding domain protein
H7677_RS07985	COG0142	geranyltranstransferase activity
H7677_RS07990	COG1252	NADH dehydrogenase
H7677_RS08000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7677_RS08005	COG0569	domain protein
H7677_RS08010	COG0534	Mate efflux family protein
H7677_RS08020	COG4224	UPF0291 protein
H7677_RS08025	COG0751	glycine-tRNA ligase activity
H7677_RS08050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7677_RS08055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7677_RS08060	COG1464	Belongs to the NlpA lipoprotein family
H7677_RS08070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7677_RS08075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H7677_RS08080	COG2252	PERMEase
H7677_RS08085	COG0561	phosphatase activity
H7677_RS08095	COG3715	PTS system
H7677_RS08100	COG3716	PTS system mannose fructose sorbose family IID component
H7677_RS08130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H7677_RS08175	COG0439	Biotin carboxylase
H7677_RS08195	COG1028	Short-chain dehydrogenase reductase Sdr
H7677_RS08200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7677_RS08205	COG2070	2-Nitropropane dioxygenase
H7677_RS08215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7677_RS08225	COG1024	Enoyl-CoA hydratase
H7677_RS08230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7677_RS08235	COG0527	aspartate kinase activity
H7677_RS08240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7677_RS08245	COG0736	holo-[acyl-carrier-protein] synthase activity
H7677_RS08250	COG0653	protein targeting
H7677_RS08260	COG1940	carbohydrate kinase activity
H7677_RS08265	COG2190	(PTS) system
H7677_RS08265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7677_RS08265	COG1263	PTS System
H7677_RS08270	COG1621	beta-fructofuranosidase activity
H7677_RS08275	COG1609	Transcriptional regulator
H7677_RS08280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7677_RS08295	COG0006	proline dipeptidase activity
H7677_RS08310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7677_RS08325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H7677_RS08330	COG0629	single-stranded DNA binding
H7677_RS08340	COG0095	Lipoate-protein ligase
H7677_RS08355	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7677_RS08360	COG0022	dehydrogenase e1 component
H7677_RS08360	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7677_RS08365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7677_RS08370	COG2860	membrane
H7677_RS08385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7677_RS08390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H7677_RS08400	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H7677_RS08405	COG0195	Participates in both transcription termination and antitermination
H7677_RS08415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7677_RS08425	COG4473	ABC transporter
H7677_RS08430	COG1131	(ABC) transporter
H7677_RS08435	COG0537	adenosine 5'-monophosphoramidase activity
H7677_RS08445	COG1316	TRANSCRIPTIONal
H7677_RS08455	COG0802	atpase or kinase
H7677_RS08460	COG1461	Dihydroxyacetone kinase
H7677_RS08470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7677_RS08475	COG0601	transmembrane transport
H7677_RS08480	COG4608	Belongs to the ABC transporter superfamily
H7677_RS08495	COG1686	Belongs to the peptidase S11 family
H7677_RS08510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7677_RS08515	COG0719	Fe-S assembly protein
H7677_RS08525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7677_RS08530	COG4862	establishment of competence for transformation
H7677_RS08535	COG1968	undecaprenyl-diphosphatase activity
H7677_RS08540	COG0765	amino acid transport
H7677_RS08570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7677_RS08575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7677_RS08580	COG0440	acetolactate synthase activity
H7677_RS08585	COG0028	Belongs to the TPP enzyme family
H7677_RS08590	COG0463	Glycosyl transferase, family 2
H7677_RS08605	COG0129	dihydroxy-acid dehydratase activity
H7677_RS08615	COG2151	metal-sulfur cluster biosynthetic enzyme
H7677_RS08660	COG1674	ftsk spoiiie
H7677_RS08760	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7677_RS08780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7677_RS08795	COG3842	ATPase activity
H7677_RS08805	COG4753	response regulator
H7677_RS08805	COG2207	Transcriptional regulator
H7677_RS08810	COG2972	Histidine kinase
H7677_RS08820	COG1653	transport
H7677_RS08825	COG0395	ABC-type sugar transport system, permease component
H7677_RS08830	COG1175	transmembrane transport
H7677_RS08845	COG0383	alpha-mannosidase activity
H7677_RS08865	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H7677_RS08890	COG1045	serine acetyltransferase
H7677_RS08895	COG1185	polyribonucleotide nucleotidyltransferase activity
H7677_RS08900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H7677_RS08905	COG1131	(ABC) transporter
H7677_RS08945	COG1187	pseudouridine synthase activity
H7677_RS08965	COG0242	peptide deformylase activity
H7677_RS08975	COG0066	3-isopropylmalate dehydratase activity
H7677_RS09000	COG2309	aminopeptidase activity
H7677_RS09015	COG2176	DNA-directed DNA polymerase activity
H7677_RS09020	COG2376	Dihydroxyacetone kinase
H7677_RS09030	COG2376	Dihydroxyacetone kinase
H7677_RS09035	COG1461	Dihydroxyacetone kinase
H7677_RS09040	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
H7677_RS09045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7677_RS09050	COG0442	prolyl-tRNA aminoacylation
H7677_RS09060	COG4589	Belongs to the CDS family
H7677_RS09065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7677_RS09070	COG1862	Preprotein translocase
H7677_RS09080	COG2918	glutathione biosynthetic process
H7677_RS09080	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7677_RS09090	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7677_RS09095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7677_RS09100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7677_RS09105	COG0542	response to heat
H7677_RS09110	COG4463	regulation of RNA biosynthetic process
H7677_RS09125	COG4509	Sortase family
H7677_RS09145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H7677_RS09275	COG0582	viral genome integration into host DNA
H7677_RS09330	COG1484	DNA-dependent DNA replication
H7677_RS09340	COG0305	Participates in initiation and elongation during chromosome replication
H7677_RS09375	COG3561	AntA/AntB antirepressor
H7677_RS09405	COG0582	viral genome integration into host DNA
H7677_RS09425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7677_RS09430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7677_RS09435	COG0492	ferredoxin-NADP+ reductase activity
H7677_RS09440	COG0564	pseudouridine synthase activity
H7677_RS09445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7677_RS09465	COG1564	THIamine pyrophosphokinase
H7677_RS09475	COG1162	GTPase activity
H7677_RS09485	COG1132	(ABC) transporter
H7677_RS09510	COG4115	mRNA cleavage
H7677_RS09535	COG0084	hydrolase, TatD family'
H7677_RS09545	COG1847	R3H domain protein
H7677_RS09555	COG0594	ribonuclease P activity
H7677_RS09560	COG0165	Argininosuccinate lyase
H7677_RS09565	COG0137	argininosuccinate synthase activity
H7677_RS09575	COG1827	regulation of RNA biosynthetic process
H7677_RS09640	COG0756	dUTP diphosphatase activity
H7677_RS09645	COG1132	(ABC) transporter
H7677_RS09650	COG1132	(ABC) transporter
H7677_RS09660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H7677_RS09665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7677_RS09670	COG0705	Rhomboid family
H7677_RS09675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7677_RS09680	COG1473	amidohydrolase
H7677_RS09685	COG2171	N-acyltransferase activity
H7677_RS09690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7677_RS09720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7677_RS09745	COG3623	hexulose-6-phosphate isomerase
H7677_RS09770	COG1523	belongs to the glycosyl hydrolase 13 family
H7677_RS09775	COG1609	Transcriptional regulator
H7677_RS09780	COG1126	abc transporter atp-binding protein
H7677_RS09785	COG0765	amino acid transport
H7677_RS09790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7677_RS09795	COG3942	CHAP domain
H7677_RS09800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7677_RS09810	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7677_RS09820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7677_RS09820	COG3711	transcriptional antiterminator
H7677_RS09830	COG2723	6-phospho-beta-galactosidase activity
H7677_RS09835	COG1486	melibiose metabolic process
H7677_RS09855	COG3590	peptidase
H7677_RS09860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7677_RS09865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7677_RS09865	COG1321	iron dependent repressor
H7677_RS09870	COG1121	(ABC) transporter
H7677_RS09875	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7677_RS09900	COG1490	D-aminoacyl-tRNA deacylase activity
H7677_RS09910	COG0737	Belongs to the 5'-nucleotidase family
H7677_RS09950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7677_RS09975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7677_RS10005	COG1328	CTP reductase activity
H7677_RS10035	COG1438	arginine binding
H7677_RS10040	COG0018	arginyl-trna synthetase
H7677_RS10060	COG1640	4-alpha-glucanotransferase
H7677_RS10065	COG2182	Extracellular solute-binding protein
H7677_RS10070	COG1175	transmembrane transport
H7677_RS10075	COG3833	ABC-type maltose transport systems, permease component
H7677_RS10080	COG5521	maltodextrose utilization protein MalA
H7677_RS10085	COG1609	Transcriptional regulator
H7677_RS10090	COG1523	belongs to the glycosyl hydrolase 13 family
H7677_RS10095	COG1780	Probably involved in ribonucleotide reductase function
H7677_RS10100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7677_RS10105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H7677_RS10110	COG2153	protein acetylation
H7677_RS10115	COG4989	oxidoreductase activity
H7677_RS10120	COG1215	transferase activity, transferring glycosyl groups
H7677_RS10125	COG1472	Belongs to the glycosyl hydrolase 3 family
H7677_RS10215	COG1484	DNA-dependent DNA replication
H7677_RS10250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H7677_RS10260	COG0305	Participates in initiation and elongation during chromosome replication
H7677_RS10265	COG0359	binds to the 23S rRNA
H7677_RS10275	COG0445	tRNA wobble uridine modification
H7677_RS10280	COG0494	nUDIX hydrolase
H7677_RS10285	COG1733	regulation of RNA biosynthetic process
H7677_RS10295	COG0482	sulfurtransferase activity
H7677_RS10300	COG1760	l-serine dehydratase
H7677_RS10305	COG1760	l-serine dehydratase
H7677_RS10315	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7677_RS10320	COG1122	ATPase activity
H7677_RS10325	COG1122	ATPase activity
H7677_RS10330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7677_RS10335	COG1426	Protein conserved in bacteria
H7677_RS10340	COG0612	Peptidase, M16
H7677_RS10345	COG0612	Peptidase, M16
H7677_RS10355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7677_RS10360	COG0516	GMP reductase activity
H7677_RS10360	COG0517	IMP dehydrogenase activity
H7677_RS10370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7677_RS10375	COG0488	(ABC) transporter
H7677_RS10405	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H7677_RS10410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7677_RS10415	COG1475	DNA binding