locus-tag	class	description
NQZ91_RS00010	COG0270	DNA (cytosine-5-)-methyltransferase activity
NQZ91_RS00045	COG3344	reverse transcriptase
NQZ91_RS00100	COG0647	UMP catabolic process
NQZ91_RS00110	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NQZ91_RS00115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NQZ91_RS00120	COG1970	mechanosensitive ion channel activity
NQZ91_RS00125	COG0358	DNA primase activity
NQZ91_RS00130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NQZ91_RS00135	COG2151	metal-sulfur cluster biosynthetic enzyme
NQZ91_RS00140	COG1982	Orn Lys Arg decarboxylase major
NQZ91_RS00145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NQZ91_RS00210	COG1131	(ABC) transporter
NQZ91_RS00215	COG1725	Transcriptional regulator
NQZ91_RS00225	COG0205	6-phosphofructokinase activity
NQZ91_RS00230	COG0469	pyruvate kinase activity
NQZ91_RS00235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NQZ91_RS00240	COG0657	acetylesterase activity
NQZ91_RS00240	COG2755	lipolytic protein G-D-S-L family
NQZ91_RS00250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NQZ91_RS00255	COG0765	amino acid transport
NQZ91_RS00260	COG1126	abc transporter atp-binding protein
NQZ91_RS00265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQZ91_RS00270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NQZ91_RS00290	COG3759	membrane
NQZ91_RS00310	COG1695	Transcriptional regulator
NQZ91_RS00320	COG2195	Cleaves the N-terminal amino acid of tripeptides
NQZ91_RS00325	COG0561	phosphatase activity
NQZ91_RS00365	COG0463	Glycosyl transferase, family 2
NQZ91_RS00365	COG1216	Glycosyl transferase, family 2
NQZ91_RS00375	COG0488	(ABC) transporter
NQZ91_RS00385	COG2226	methyltransferase
NQZ91_RS00390	COG3442	glutamine amidotransferase
NQZ91_RS00395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NQZ91_RS00400	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NQZ91_RS00410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQZ91_RS00415	COG0488	(ABC) transporter
NQZ91_RS00420	COG2226	methyltransferase
NQZ91_RS00435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NQZ91_RS00440	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NQZ91_RS00440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NQZ91_RS00460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQZ91_RS00465	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NQZ91_RS00475	COG2384	SAM-dependent methyltransferase
NQZ91_RS00480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NQZ91_RS00490	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NQZ91_RS00505	COG1088	dTDP-glucose 4,6-dehydratase activity
NQZ91_RS00510	COG1091	dTDP-4-dehydrorhamnose reductase activity
NQZ91_RS00515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQZ91_RS00520	COG4684	Psort location CytoplasmicMembrane, score
NQZ91_RS00525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NQZ91_RS00535	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NQZ91_RS00540	COG0488	(ABC) transporter
NQZ91_RS00555	COG1126	abc transporter atp-binding protein
NQZ91_RS00590	COG0438	transferase activity, transferring glycosyl groups
NQZ91_RS00605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NQZ91_RS00625	COG0765	amino acid transport
NQZ91_RS00630	COG0765	amino acid transport
NQZ91_RS00635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQZ91_RS00645	COG0745	RESPONSE REGULATOR receiver
NQZ91_RS00655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NQZ91_RS00660	COG0768	penicillin binding
NQZ91_RS00690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NQZ91_RS00720	COG0481	GTPase activity
NQZ91_RS00740	COG1902	pentaerythritol trinitrate reductase activity
NQZ91_RS00745	COG0789	Transcriptional regulator
NQZ91_RS00750	COG0656	L-ascorbic acid biosynthetic process
NQZ91_RS00755	COG1011	Hydrolase
NQZ91_RS00765	COG4640	response to antibiotic
NQZ91_RS00785	COG0583	DNA-binding transcription factor activity
NQZ91_RS00790	COG2610	gluconate transmembrane transporter activity
NQZ91_RS00795	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQZ91_RS00800	COG0183	Belongs to the thiolase family
NQZ91_RS00810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NQZ91_RS00815	COG1024	Enoyl-CoA hydratase
NQZ91_RS00820	COG1960	acyl-CoA dehydrogenase activity
NQZ91_RS00825	COG1024	Enoyl-CoA hydratase
NQZ91_RS00835	COG1131	(ABC) transporter
NQZ91_RS00865	COG2984	ABC transporter substrate binding protein
NQZ91_RS00875	COG4120	Belongs to the binding-protein-dependent transport system permease family
NQZ91_RS00880	COG1116	anion transmembrane transporter activity
NQZ91_RS00880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQZ91_RS00885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NQZ91_RS00890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NQZ91_RS00895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NQZ91_RS00900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NQZ91_RS00910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NQZ91_RS00915	COG0077	Prephenate dehydratase
NQZ91_RS00980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NQZ91_RS01005	COG0270	DNA (cytosine-5-)-methyltransferase activity
NQZ91_RS01040	COG4695	Portal protein
NQZ91_RS01045	COG0740	serine-type endopeptidase activity
NQZ91_RS01115	COG1388	LysM domain
NQZ91_RS01115	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQZ91_RS01200	COG0539	negative regulation of cytoplasmic translation
NQZ91_RS01215	COG1104	cysteine desulfurase activity
NQZ91_RS01220	COG0301	tRNA thio-modification
NQZ91_RS01225	COG1114	Component of the transport system for branched-chain amino acids
NQZ91_RS01230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NQZ91_RS01235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NQZ91_RS01245	COG0583	DNA-binding transcription factor activity
NQZ91_RS01255	COG0564	pseudouridine synthase activity
NQZ91_RS01260	COG2824	Alkylphosphonate utilization operon protein PhnA
NQZ91_RS01270	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NQZ91_RS01275	COG0540	Belongs to the ATCase OTCase family
NQZ91_RS01280	COG0505	Belongs to the CarA family
NQZ91_RS01300	COG0726	polysaccharide deacetylase
NQZ91_RS01310	COG0083	homoserine kinase activity
NQZ91_RS01315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NQZ91_RS01320	COG3842	ATPase activity
NQZ91_RS01325	COG1176	ABC-type spermidine putrescine transport system, permease component I
NQZ91_RS01330	COG1177	transmembrane transport
NQZ91_RS01335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NQZ91_RS01350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NQZ91_RS01360	COG0489	protein tyrosine kinase activity
NQZ91_RS01365	COG1215	transferase activity, transferring glycosyl groups
NQZ91_RS01380	COG1215	transferase activity, transferring glycosyl groups
NQZ91_RS01385	COG1215	transferase activity, transferring glycosyl groups
NQZ91_RS01395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NQZ91_RS01405	COG0534	Mate efflux family protein
NQZ91_RS01420	COG1435	thymidine kinase activity
NQZ91_RS01425	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NQZ91_RS01430	COG2890	protein-(glutamine-N5) methyltransferase activity
NQZ91_RS01440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NQZ91_RS01455	COG4221	oxidoreductase activity
NQZ91_RS01475	COG0584	glycerophosphoryl diester phosphodiesterase
NQZ91_RS01490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NQZ91_RS01515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQZ91_RS01530	COG2188	Transcriptional regulator
NQZ91_RS01545	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NQZ91_RS01550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NQZ91_RS01575	COG4974	Belongs to the 'phage' integrase family
NQZ91_RS01595	COG5002	protein histidine kinase activity
NQZ91_RS01600	COG0745	RESPONSE REGULATOR receiver
NQZ91_RS01620	COG1136	(ABC) transporter
NQZ91_RS01665	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NQZ91_RS01670	COG0647	UMP catabolic process
NQZ91_RS01675	COG4974	Belongs to the 'phage' integrase family
NQZ91_RS01715	COG3328	transposase activity
NQZ91_RS01795	COG3344	reverse transcriptase
NQZ91_RS01830	COG0270	DNA (cytosine-5-)-methyltransferase activity
NQZ91_RS01875	COG2176	DNA-directed DNA polymerase activity
NQZ91_RS01880	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NQZ91_RS01890	COG0305	Participates in initiation and elongation during chromosome replication
NQZ91_RS01900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQZ91_RS01925	COG0488	(ABC) transporter
NQZ91_RS01940	COG0222	ribosome binding
NQZ91_RS01945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NQZ91_RS01960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NQZ91_RS01965	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NQZ91_RS01990	COG1940	carbohydrate kinase activity
NQZ91_RS02000	COG0488	(ABC) transporter
NQZ91_RS02005	COG0617	tRNA 3'-terminal CCA addition
NQZ91_RS02010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NQZ91_RS02015	COG1307	EDD domain protein, DegV family
NQZ91_RS02025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NQZ91_RS02025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQZ91_RS02025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NQZ91_RS02030	COG1105	Belongs to the carbohydrate kinase PfkB family
NQZ91_RS02035	COG1349	DNA-binding transcription factor activity
NQZ91_RS02040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NQZ91_RS02065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NQZ91_RS02070	COG0336	Belongs to the RNA methyltransferase TrmD family
NQZ91_RS02075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NQZ91_RS02085	COG1132	(ABC) transporter
NQZ91_RS02095	COG1837	Belongs to the UPF0109 family
NQZ91_RS02110	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NQZ91_RS02120	COG0604	alcohol dehydrogenase
NQZ91_RS02130	COG1164	Oligoendopeptidase f
NQZ91_RS02145	COG0346	lactoylglutathione lyase activity
NQZ91_RS02160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NQZ91_RS02175	COG0446	pyridine nucleotide-disulphide oxidoreductase
NQZ91_RS02180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQZ91_RS02190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NQZ91_RS02205	COG0210	DNA helicase
NQZ91_RS02230	COG0072	phenylalanine-tRNA ligase activity
NQZ91_RS02230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQZ91_RS02260	COG1028	Short-chain dehydrogenase reductase Sdr
NQZ91_RS02265	COG1312	Catalyzes the dehydration of D-mannonate
NQZ91_RS02275	COG0800	Aldolase
NQZ91_RS02285	COG3250	beta-galactosidase activity
NQZ91_RS02295	COG2211	Major facilitator Superfamily
NQZ91_RS02310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NQZ91_RS02320	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NQZ91_RS02325	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NQZ91_RS02330	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NQZ91_RS02335	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NQZ91_RS02340	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQZ91_RS02345	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NQZ91_RS02350	COG0356	it plays a direct role in the translocation of protons across the membrane
NQZ91_RS02360	COG1597	lipid kinase activity
NQZ91_RS02375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NQZ91_RS02390	COG0552	protein localization to endoplasmic reticulum
NQZ91_RS02395	COG0561	phosphatase activity
NQZ91_RS02400	COG0561	phosphatase activity
NQZ91_RS02405	COG1196	nuclear chromosome segregation
NQZ91_RS02440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQZ91_RS02445	COG0538	isocitrate dehydrogenase activity
NQZ91_RS02450	COG0372	Belongs to the citrate synthase family
NQZ91_RS02455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NQZ91_RS02460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NQZ91_RS02465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQZ91_RS02470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQZ91_RS02495	COG1476	TRANSCRIPTIONal
NQZ91_RS02520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQZ91_RS02525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NQZ91_RS02535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NQZ91_RS02540	COG4122	O-methyltransferase activity
NQZ91_RS02555	COG0708	Exodeoxyribonuclease III
NQZ91_RS02565	COG1393	Belongs to the ArsC family
NQZ91_RS02570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NQZ91_RS02575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NQZ91_RS02585	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NQZ91_RS02595	COG4467	Involved in initiation control of chromosome replication
NQZ91_RS02600	COG0470	DNA polymerase III
NQZ91_RS02605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NQZ91_RS02610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQZ91_RS02615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NQZ91_RS02620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NQZ91_RS02645	COG0653	protein targeting
NQZ91_RS02655	COG1073	alpha beta
NQZ91_RS02705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NQZ91_RS02715	COG0187	DNA topoisomerase II activity
NQZ91_RS02735	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NQZ91_RS02740	COG0463	Glycosyl transferase, family 2
NQZ91_RS02750	COG0284	orotidine-5'-phosphate decarboxylase activity
NQZ91_RS02770	COG0559	Belongs to the binding-protein-dependent transport system permease family
NQZ91_RS02790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NQZ91_RS02795	COG0110	maltose O-acetyltransferase activity
NQZ91_RS02800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NQZ91_RS02805	COG0626	cystathionine gamma-synthase activity
NQZ91_RS02820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NQZ91_RS02825	COG0386	Belongs to the glutathione peroxidase family
NQZ91_RS02830	COG1187	pseudouridine synthase activity
NQZ91_RS02835	COG0435	Glutathione S-transferase
NQZ91_RS02845	COG0363	glucosamine-6-phosphate deaminase activity
NQZ91_RS02860	COG1438	arginine binding
NQZ91_RS02870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQZ91_RS02875	COG1288	antiporter activity
NQZ91_RS02880	COG0436	Aminotransferase
NQZ91_RS02885	COG0549	Belongs to the carbamate kinase family
NQZ91_RS02890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NQZ91_RS02895	COG0454	-acetyltransferase
NQZ91_RS02920	COG0737	Belongs to the 5'-nucleotidase family
NQZ91_RS02925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NQZ91_RS02935	COG1466	dna polymerase III delta subunit
NQZ91_RS02940	COG1686	Belongs to the peptidase S11 family
NQZ91_RS02945	COG1876	peptidase activity
NQZ91_RS02960	COG1074	ATP-dependent DNA helicase activity
NQZ91_RS02965	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NQZ91_RS02995	COG0732	type I restriction modification DNA specificity domain
NQZ91_RS03005	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NQZ91_RS03010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NQZ91_RS03015	COG5002	protein histidine kinase activity
NQZ91_RS03020	COG0745	RESPONSE REGULATOR receiver
NQZ91_RS03040	COG2873	o-acetylhomoserine
NQZ91_RS03075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NQZ91_RS03080	COG0758	DNA mediated transformation
NQZ91_RS03085	COG1937	Protein conserved in bacteria
NQZ91_RS03090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NQZ91_RS03095	COG0446	pyridine nucleotide-disulphide oxidoreductase
NQZ91_RS03105	COG1272	protein, Hemolysin III
NQZ91_RS03110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NQZ91_RS03140	COG1704	LemA family
NQZ91_RS03150	COG1573	uracil-dna glycosylase
NQZ91_RS03160	COG0390	transport system, permease component
NQZ91_RS03165	COG4619	ABC transporter
NQZ91_RS03170	COG0662	Cupin 2, conserved barrel domain protein
NQZ91_RS03185	COG0300	oxidoreductase activity
NQZ91_RS03190	COG1234	tRNA 3'-trailer cleavage
NQZ91_RS03200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NQZ91_RS03205	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NQZ91_RS03215	COG2807	transmembrane transport
NQZ91_RS03220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NQZ91_RS03225	COG2610	gluconate transmembrane transporter activity
NQZ91_RS03245	COG0302	gtp cyclohydrolase
NQZ91_RS03250	COG1051	belongs to the nudix hydrolase family
NQZ91_RS03265	COG0517	IMP dehydrogenase activity
NQZ91_RS03275	COG5416	Lipopolysaccharide assembly protein A domain
NQZ91_RS03290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NQZ91_RS03295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NQZ91_RS03300	COG0297	glycogen (starch) synthase activity
NQZ91_RS03310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQZ91_RS03345	COG0436	Aminotransferase
NQZ91_RS03370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQZ91_RS03375	COG1960	acyl-CoA dehydrogenase activity
NQZ91_RS03380	COG0583	DNA-binding transcription factor activity
NQZ91_RS03385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NQZ91_RS03390	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NQZ91_RS03395	COG1024	Enoyl-CoA hydratase
NQZ91_RS03405	COG0183	Belongs to the thiolase family
NQZ91_RS03410	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQZ91_RS03415	COG1960	acyl-CoA dehydrogenase activity
NQZ91_RS03425	COG2030	dehydratase
NQZ91_RS03430	COG0596	Alpha beta hydrolase
NQZ91_RS03450	COG2333	competence protein COMEC
NQZ91_RS03450	COG0658	competence protein
NQZ91_RS03455	COG1596	polysaccharide export
NQZ91_RS03455	COG1555	photosystem II stabilization
NQZ91_RS03460	COG0204	Acyl-transferase
NQZ91_RS03470	COG1063	alcohol dehydrogenase
NQZ91_RS03480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NQZ91_RS03485	COG0557	exoribonuclease II activity
NQZ91_RS03495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NQZ91_RS03500	COG2814	Major facilitator Superfamily
NQZ91_RS03510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NQZ91_RS03520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NQZ91_RS03525	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NQZ91_RS03545	COG1733	regulation of RNA biosynthetic process
NQZ91_RS03550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NQZ91_RS03565	COG2514	catechol 2,3-dioxygenase activity
NQZ91_RS03575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NQZ91_RS03595	COG1132	(ABC) transporter
NQZ91_RS03605	COG0280	phosphate acetyltransferase
NQZ91_RS03610	COG0564	pseudouridine synthase activity
NQZ91_RS03615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NQZ91_RS03620	COG2357	RelA SpoT domain protein
NQZ91_RS03635	COG1104	cysteine desulfurase activity
NQZ91_RS03660	COG3764	Sortase (surface protein transpeptidase)
NQZ91_RS03665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NQZ91_RS03670	COG0039	L-malate dehydrogenase activity
NQZ91_RS03675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NQZ91_RS03680	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQZ91_RS03685	COG4603	Belongs to the binding-protein-dependent transport system permease family
NQZ91_RS03690	COG3845	ABC transporter
NQZ91_RS03695	COG1744	ABC transporter substrate-binding protein PnrA-like
NQZ91_RS03700	COG0295	cytidine deaminase activity
NQZ91_RS03710	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NQZ91_RS03715	COG2813	Specifically methylates the guanine in position
NQZ91_RS03720	COG1072	(Pantothenic acid kinase))
NQZ91_RS03725	COG0268	Binds directly to 16S ribosomal RNA
NQZ91_RS03730	COG5002	protein histidine kinase activity
NQZ91_RS03735	COG0745	RESPONSE REGULATOR receiver
NQZ91_RS03745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NQZ91_RS03755	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NQZ91_RS03785	COG0463	Glycosyl transferase, family 2
NQZ91_RS03800	COG0463	Glycosyl transferase, family 2
NQZ91_RS03825	COG0463	Glycosyl transferase, family 2
NQZ91_RS03835	COG1705	Flagellar rod assembly protein muramidase FlgJ
NQZ91_RS03840	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQZ91_RS03845	COG1481	regulation of sporulation
NQZ91_RS03855	COG1660	Displays ATPase and GTPase activities
NQZ91_RS03860	COG0251	oxidation-reduction process
NQZ91_RS03895	COG3842	ATPase activity
NQZ91_RS03910	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NQZ91_RS03915	COG5002	protein histidine kinase activity
NQZ91_RS03930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NQZ91_RS03935	COG0581	inorganic phosphate transmembrane transporter activity
NQZ91_RS03940	COG0573	inorganic phosphate transmembrane transporter activity
NQZ91_RS03950	COG3527	Alpha-acetolactate decarboxylase
NQZ91_RS03960	COG0628	permease
NQZ91_RS03965	COG2706	6-phosphogluconolactonase activity
NQZ91_RS03975	COG1011	Hydrolase
NQZ91_RS03980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQZ91_RS04025	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQZ91_RS04025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQZ91_RS04050	COG3679	Belongs to the UPF0342 family
NQZ91_RS04055	COG0287	Prephenate dehydrogenase
NQZ91_RS04060	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NQZ91_RS04065	COG0710	3-dehydroquinate dehydratase activity
NQZ91_RS04070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NQZ91_RS04075	COG1368	sulfuric ester hydrolase activity
NQZ91_RS04080	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NQZ91_RS04085	COG0187	DNA topoisomerase II activity
NQZ91_RS04090	COG0704	Plays a role in the regulation of phosphate uptake
NQZ91_RS04095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NQZ91_RS04105	COG0581	inorganic phosphate transmembrane transporter activity
NQZ91_RS04110	COG0573	inorganic phosphate transmembrane transporter activity
NQZ91_RS04120	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NQZ91_RS04120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NQZ91_RS04125	COG0483	inositol monophosphate 1-phosphatase activity
NQZ91_RS04130	COG4476	Belongs to the UPF0223 family
NQZ91_RS04135	COG1393	Belongs to the ArsC family
NQZ91_RS04140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NQZ91_RS04145	COG0196	riboflavin kinase activity
NQZ91_RS04150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NQZ91_RS04160	COG1621	beta-fructofuranosidase activity
NQZ91_RS04165	COG1653	transport
NQZ91_RS04170	COG0395	ABC-type sugar transport system, permease component
NQZ91_RS04175	COG4209	transmembrane transport
NQZ91_RS04180	COG1609	Transcriptional regulator
NQZ91_RS04200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQZ91_RS04205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NQZ91_RS04215	COG0494	nUDIX hydrolase
NQZ91_RS04220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NQZ91_RS04250	COG1028	Short-chain dehydrogenase reductase Sdr
NQZ91_RS04275	COG0577	efflux transmembrane transporter activity
NQZ91_RS04280	COG1136	(ABC) transporter
NQZ91_RS04285	COG2205	protein histidine kinase activity
NQZ91_RS04290	COG0745	RESPONSE REGULATOR receiver
NQZ91_RS04300	COG4607	ABC-type enterochelin transport system periplasmic component
NQZ91_RS04305	COG4604	ABC transporter, ATP-binding protein
NQZ91_RS04310	COG4605	iron ion homeostasis
NQZ91_RS04315	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQZ91_RS04325	COG1227	inorganic diphosphatase activity
NQZ91_RS04340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQZ91_RS04355	COG0395	ABC-type sugar transport system, permease component
NQZ91_RS04360	COG1175	transmembrane transport
NQZ91_RS04375	COG1263	PTS System
NQZ91_RS04375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQZ91_RS04375	COG2190	(PTS) system
NQZ91_RS04380	COG1011	Hydrolase
NQZ91_RS04385	COG0490	domain, Protein
NQZ91_RS04415	COG2261	transglycosylase associated protein
NQZ91_RS04425	COG1132	(ABC) transporter
NQZ91_RS04430	COG1132	(ABC) transporter
NQZ91_RS04555	COG1783	phage Terminase large subunit
NQZ91_RS04600	COG0270	DNA (cytosine-5-)-methyltransferase activity
NQZ91_RS04705	COG4974	Belongs to the 'phage' integrase family
NQZ91_RS04720	COG1702	phosphate starvation-inducible protein PhoH
NQZ91_RS04725	COG4479	Belongs to the UPF0346 family
NQZ91_RS04740	COG2996	Protein conserved in bacteria
NQZ91_RS04745	COG0233	cytoplasmic translational termination
NQZ91_RS04750	COG0528	UMP kinase activity
NQZ91_RS04755	COG0625	glutathione transferase activity
NQZ91_RS04780	COG0346	lactoylglutathione lyase activity
NQZ91_RS04785	COG1674	ftsk spoiiie
NQZ91_RS04790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NQZ91_RS04795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NQZ91_RS04810	COG4750	Nucleotidyl transferase
NQZ91_RS04820	COG1213	nucleotidyl transferase
NQZ91_RS04825	COG3475	LICD family
NQZ91_RS04840	COG1216	Glycosyl transferase, family 2
NQZ91_RS04855	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NQZ91_RS04860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NQZ91_RS04860	COG0463	Glycosyl transferase, family 2
NQZ91_RS04865	COG0438	transferase activity, transferring glycosyl groups
NQZ91_RS04875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NQZ91_RS04880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NQZ91_RS04895	COG3944	biosynthesis protein
NQZ91_RS04910	COG3022	response to hydroperoxide
NQZ91_RS04915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQZ91_RS04920	COG1307	EDD domain protein, DegV family
NQZ91_RS04930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NQZ91_RS04935	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NQZ91_RS04940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NQZ91_RS04945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NQZ91_RS04945	COG1199	ATP-dependent helicase activity
NQZ91_RS04955	COG2177	Part of the ABC transporter FtsEX involved in
NQZ91_RS04960	COG2884	Cell division ATP-binding protein ftsE
NQZ91_RS04970	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NQZ91_RS05000	COG1078	dGTPase activity
NQZ91_RS05030	COG2244	polysaccharide biosynthetic process
NQZ91_RS05035	COG0149	triose-phosphate isomerase activity
NQZ91_RS05045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NQZ91_RS05060	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NQZ91_RS05065	COG0772	Belongs to the SEDS family
NQZ91_RS05085	COG3859	Proton-coupled thiamine transporter YuaJ
NQZ91_RS05095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NQZ91_RS05100	COG0406	alpha-ribazole phosphatase activity
NQZ91_RS05105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NQZ91_RS05110	COG2176	DNA-directed DNA polymerase activity
NQZ91_RS05120	COG0577	efflux transmembrane transporter activity
NQZ91_RS05125	COG1136	(ABC) transporter
NQZ91_RS05130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NQZ91_RS05135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NQZ91_RS05140	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NQZ91_RS05145	COG1268	BioY protein
NQZ91_RS05150	COG4443	Transcriptional Coactivator p15 (PC4)
NQZ91_RS05160	COG0826	peptidase U32
NQZ91_RS05175	COG2188	Transcriptional regulator
NQZ91_RS05190	COG2217	Heavy metal translocating P-type atpase
NQZ91_RS05240	COG2137	regulation of response to DNA damage stimulus
NQZ91_RS05245	COG3557	Belongs to the UPF0374 family
NQZ91_RS05255	COG4224	UPF0291 protein
NQZ91_RS05260	COG0751	glycine-tRNA ligase activity
NQZ91_RS05280	COG0371	Dehydrogenase
NQZ91_RS05290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NQZ91_RS05295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQZ91_RS05310	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NQZ91_RS05315	COG4608	Belongs to the ABC transporter superfamily
NQZ91_RS05320	COG0444	Belongs to the ABC transporter superfamily
NQZ91_RS05325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQZ91_RS05330	COG0601	transmembrane transport
NQZ91_RS05340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NQZ91_RS05345	COG0768	penicillin binding
NQZ91_RS05355	COG0275	rRNA processing
NQZ91_RS05390	COG1054	Belongs to the UPF0176 family
NQZ91_RS05395	COG4720	Psort location CytoplasmicMembrane, score
NQZ91_RS05405	COG0095	Lipoate-protein ligase
NQZ91_RS05410	COG2723	6-phospho-beta-galactosidase activity
NQZ91_RS05425	COG2723	6-phospho-beta-galactosidase activity
NQZ91_RS05430	COG0346	lactoylglutathione lyase activity
NQZ91_RS05435	COG2723	6-phospho-beta-galactosidase activity
NQZ91_RS05440	COG2207	Transcriptional regulator
NQZ91_RS05455	COG3711	transcriptional antiterminator
NQZ91_RS05460	COG0561	phosphatase activity
NQZ91_RS05465	COG1940	carbohydrate kinase activity
NQZ91_RS05545	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NQZ91_RS05565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQZ91_RS05590	COG3842	ATPase activity
NQZ91_RS05595	COG0544	peptidyl-prolyl cis-trans isomerase activity
NQZ91_RS05620	COG4475	Protein of unknown function (DUF436)
NQZ91_RS05630	COG0351	phosphomethylpyrimidine kinase
NQZ91_RS05645	COG2217	Heavy metal translocating P-type atpase
NQZ91_RS05665	COG3655	Transcriptional regulator
NQZ91_RS05675	COG0765	amino acid transport
NQZ91_RS05680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQZ91_RS05690	COG0095	Lipoate-protein ligase
NQZ91_RS05695	COG0484	heat shock protein binding
NQZ91_RS05700	COG0443	Heat shock 70 kDa protein
NQZ91_RS05710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NQZ91_RS05715	COG1420	regulation of RNA biosynthetic process
NQZ91_RS05740	COG1396	sequence-specific DNA binding
NQZ91_RS05755	COG0588	phosphoglycerate mutase activity
NQZ91_RS05760	COG2848	UPF0210 protein
NQZ91_RS05765	COG3830	Belongs to the UPF0237 family
NQZ91_RS05770	COG1132	(ABC) transporter
NQZ91_RS05775	COG1132	(ABC) transporter
NQZ91_RS05785	COG1304	FMN binding
NQZ91_RS05815	COG0534	Mate efflux family protein
NQZ91_RS05830	COG1454	alcohol dehydrogenase
NQZ91_RS05830	COG1012	belongs to the aldehyde dehydrogenase family
NQZ91_RS05840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NQZ91_RS05845	COG1511	domain protein
NQZ91_RS05850	COG1309	transcriptional regulator
NQZ91_RS05855	COG0561	phosphatase activity
NQZ91_RS05890	COG0167	dihydroorotate dehydrogenase activity
NQZ91_RS05895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NQZ91_RS05900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NQZ91_RS05935	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NQZ91_RS05960	COG1045	serine acetyltransferase
NQZ91_RS05965	COG1185	polyribonucleotide nucleotidyltransferase activity
NQZ91_RS05975	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NQZ91_RS05995	COG1174	glycine betaine transport
NQZ91_RS06000	COG0517	IMP dehydrogenase activity
NQZ91_RS06000	COG1125	glycine betaine transport
NQZ91_RS06025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQZ91_RS06035	COG3655	Transcriptional regulator
NQZ91_RS06045	COG1187	pseudouridine synthase activity
NQZ91_RS06055	COG0242	peptide deformylase activity
NQZ91_RS06080	COG0066	3-isopropylmalate dehydratase activity
NQZ91_RS06085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NQZ91_RS06105	COG2309	aminopeptidase activity
NQZ91_RS06110	COG2176	DNA-directed DNA polymerase activity
NQZ91_RS06115	COG2376	Dihydroxyacetone kinase
NQZ91_RS06125	COG2376	Dihydroxyacetone kinase
NQZ91_RS06130	COG1461	Dihydroxyacetone kinase
NQZ91_RS06135	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NQZ91_RS06145	COG0442	prolyl-tRNA aminoacylation
NQZ91_RS06155	COG4589	Belongs to the CDS family
NQZ91_RS06160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NQZ91_RS06180	COG1862	Preprotein translocase
NQZ91_RS06190	COG1181	Belongs to the D-alanine--D-alanine ligase family
NQZ91_RS06190	COG2918	glutathione biosynthetic process
NQZ91_RS06195	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NQZ91_RS06200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NQZ91_RS06210	COG3201	nicotinamide mononucleotide transporter
NQZ91_RS06215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NQZ91_RS06220	COG0542	response to heat
NQZ91_RS06225	COG4463	regulation of RNA biosynthetic process
NQZ91_RS06245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQZ91_RS06265	COG1564	THIamine pyrophosphokinase
NQZ91_RS06275	COG1162	GTPase activity
NQZ91_RS06315	COG4115	mRNA cleavage
NQZ91_RS06325	COG2816	NAD+ diphosphatase activity
NQZ91_RS06340	COG0084	hydrolase, TatD family'
NQZ91_RS06345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQZ91_RS06350	COG1597	lipid kinase activity
NQZ91_RS06355	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NQZ91_RS06370	COG0594	ribonuclease P activity
NQZ91_RS06380	COG0137	argininosuccinate synthase activity
NQZ91_RS06390	COG1827	regulation of RNA biosynthetic process
NQZ91_RS06405	COG2040	homocysteine
NQZ91_RS06410	COG0833	amino acid
NQZ91_RS06450	COG2081	HI0933 family
NQZ91_RS06460	COG1131	(ABC) transporter
NQZ91_RS06470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NQZ91_RS06495	COG0431	NADPH-dependent FMN reductase
NQZ91_RS06495	COG1053	succinate dehydrogenase
NQZ91_RS06495	COG3976	FMN-binding domain protein
NQZ91_RS06505	COG2832	Protein of unknown function (DUF454)
NQZ91_RS06515	COG0124	histidyl-tRNA synthetase
NQZ91_RS06525	COG2190	(PTS) system
NQZ91_RS06525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQZ91_RS06525	COG1263	PTS System
NQZ91_RS06530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NQZ91_RS06535	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NQZ91_RS06540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NQZ91_RS06555	COG1408	metallophosphoesterase
NQZ91_RS06570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NQZ91_RS06570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NQZ91_RS06575	COG1447	Phosphotransferase system cellobiose-specific component IIA
NQZ91_RS06580	COG3711	transcriptional antiterminator
NQZ91_RS06585	COG3684	Belongs to the aldolase LacD family
NQZ91_RS06590	COG1105	Belongs to the carbohydrate kinase PfkB family
NQZ91_RS06595	COG0698	ribose 5-phosphate isomerase
NQZ91_RS06600	COG0698	ribose 5-phosphate isomerase
NQZ91_RS06605	COG1349	DNA-binding transcription factor activity
NQZ91_RS06610	COG0542	response to heat
NQZ91_RS06615	COG1396	sequence-specific DNA binding
NQZ91_RS06620	COG1979	alcohol dehydrogenase
NQZ91_RS06625	COG3942	CHAP domain
NQZ91_RS06640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NQZ91_RS06645	COG0085	RNA polymerase activity
NQZ91_RS06650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NQZ91_RS06675	COG3443	Belongs to the bacterial solute-binding protein 9 family
NQZ91_RS06675	COG0803	Belongs to the bacterial solute-binding protein 9 family
NQZ91_RS06680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NQZ91_RS06685	COG1121	(ABC) transporter
NQZ91_RS06700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NQZ91_RS06705	COG1523	belongs to the glycosyl hydrolase 13 family
NQZ91_RS06710	COG1609	Transcriptional regulator
NQZ91_RS06735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NQZ91_RS06745	COG1214	PFAM Peptidase M22, glycoprotease
NQZ91_RS06755	COG5503	Protein of unknown function (DUF1447)
NQZ91_RS06770	COG0174	glutamine synthetase
NQZ91_RS06775	COG0789	Transcriptional regulator
NQZ91_RS06785	COG0126	phosphoglycerate kinase activity
NQZ91_RS06790	COG1051	belongs to the nudix hydrolase family
NQZ91_RS06795	COG0433	COG0433 Predicted ATPase
NQZ91_RS06800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NQZ91_RS06820	COG0202	RNA polymerase activity
NQZ91_RS06830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NQZ91_RS06835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NQZ91_RS06840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NQZ91_RS06845	COG0563	adenylate kinase activity
NQZ91_RS06850	COG0201	protein transport
NQZ91_RS06860	COG1841	ribosomal large subunit assembly
NQZ91_RS06865	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NQZ91_RS06870	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NQZ91_RS06875	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NQZ91_RS06880	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NQZ91_RS06885	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NQZ91_RS06890	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NQZ91_RS06895	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NQZ91_RS06900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NQZ91_RS06905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NQZ91_RS06910	COG0255	Belongs to the universal ribosomal protein uL29 family
NQZ91_RS06915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NQZ91_RS06920	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NQZ91_RS06925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NQZ91_RS06930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NQZ91_RS06935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NQZ91_RS06940	COG0089	rRNA binding
NQZ91_RS06945	COG0088	Forms part of the polypeptide exit tunnel
NQZ91_RS06950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NQZ91_RS06955	COG0051	transcription antitermination factor activity, RNA binding
NQZ91_RS06970	COG3906	Belongs to the UPF0473 family
NQZ91_RS06975	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NQZ91_RS06980	COG4472	Bacterial protein of unknown function (DUF965)
NQZ91_RS06985	COG1393	Belongs to the ArsC family
NQZ91_RS07000	COG0519	Catalyzes the synthesis of GMP from XMP
NQZ91_RS07010	COG0632	four-way junction helicase activity
NQZ91_RS07015	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NQZ91_RS07045	COG1438	arginine binding
NQZ91_RS07050	COG0018	arginyl-trna synthetase
NQZ91_RS07055	COG1388	LysM domain
NQZ91_RS07055	COG3942	CHAP domain
NQZ91_RS07100	COG1640	4-alpha-glucanotransferase
NQZ91_RS07105	COG2182	Extracellular solute-binding protein
NQZ91_RS07110	COG1175	transmembrane transport
NQZ91_RS07115	COG3833	ABC-type maltose transport systems, permease component
NQZ91_RS07120	COG5521	maltodextrose utilization protein MalA
NQZ91_RS07125	COG1609	Transcriptional regulator
NQZ91_RS07130	COG1523	belongs to the glycosyl hydrolase 13 family
NQZ91_RS07135	COG1780	Probably involved in ribonucleotide reductase function
NQZ91_RS07140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQZ91_RS07145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NQZ91_RS07150	COG2153	protein acetylation
NQZ91_RS07155	COG4989	oxidoreductase activity
NQZ91_RS07165	COG1053	succinate dehydrogenase
NQZ91_RS07175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NQZ91_RS07185	COG0305	Participates in initiation and elongation during chromosome replication
NQZ91_RS07190	COG0359	binds to the 23S rRNA
NQZ91_RS07200	COG0445	tRNA wobble uridine modification
NQZ91_RS07215	COG1051	belongs to the nudix hydrolase family
NQZ91_RS07220	COG0482	sulfurtransferase activity
NQZ91_RS07225	COG1760	l-serine dehydratase
NQZ91_RS07230	COG1760	l-serine dehydratase
NQZ91_RS07240	COG0745	RESPONSE REGULATOR receiver
NQZ91_RS07245	COG5002	protein histidine kinase activity
NQZ91_RS07260	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NQZ91_RS07265	COG1122	ATPase activity
NQZ91_RS07270	COG1122	ATPase activity
NQZ91_RS07275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NQZ91_RS07285	COG0612	Peptidase, M16
NQZ91_RS07290	COG0612	Peptidase, M16
NQZ91_RS07300	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NQZ91_RS07305	COG0517	IMP dehydrogenase activity
NQZ91_RS07305	COG0516	GMP reductase activity
NQZ91_RS07315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQZ91_RS07320	COG0488	(ABC) transporter
NQZ91_RS07350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NQZ91_RS07355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQZ91_RS07360	COG1475	DNA binding
NQZ91_RS07370	COG0592	DNA-directed DNA polymerase activity
NQZ91_RS07385	COG0012	GTP binding
NQZ91_RS07390	COG0193	aminoacyl-tRNA hydrolase activity
NQZ91_RS07395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NQZ91_RS07400	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NQZ91_RS07420	COG0037	tRNA processing
NQZ91_RS07430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQZ91_RS07570	COG3942	CHAP domain
NQZ91_RS07575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NQZ91_RS07580	COG0436	Aminotransferase
NQZ91_RS07585	COG1381	Involved in DNA repair and RecF pathway recombination
NQZ91_RS07610	COG1131	(ABC) transporter
NQZ91_RS07620	COG0416	fatty acid biosynthetic process
NQZ91_RS07625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NQZ91_RS07630	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NQZ91_RS07635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NQZ91_RS07650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NQZ91_RS07660	COG0138	bifunctional purine biosynthesis protein purh
NQZ91_RS07665	COG0151	Belongs to the GarS family
NQZ91_RS07670	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NQZ91_RS07680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NQZ91_RS07685	COG0789	Transcriptional regulator
NQZ91_RS07690	COG2255	four-way junction helicase activity
NQZ91_RS07710	COG0285	dihydrofolate synthase activity
NQZ91_RS07725	COG1328	CTP reductase activity
NQZ91_RS07735	COG0737	Belongs to the 5'-nucleotidase family
NQZ91_RS07770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NQZ91_RS07790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NQZ91_RS07820	COG0737	Belongs to the 5'-nucleotidase family
NQZ91_RS07830	COG1490	D-aminoacyl-tRNA deacylase activity
NQZ91_RS07845	COG0803	Belongs to the bacterial solute-binding protein 9 family
NQZ91_RS07850	COG1121	(ABC) transporter
NQZ91_RS07855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NQZ91_RS07855	COG1321	iron dependent repressor
NQZ91_RS07860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NQZ91_RS07865	COG3590	peptidase
NQZ91_RS07895	COG0049	tRNA binding
NQZ91_RS07900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NQZ91_RS07955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NQZ91_RS07960	COG1459	type II secretion system
NQZ91_RS07965	COG4537	Required for transformation and DNA binding
NQZ91_RS07995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NQZ91_RS08005	COG0285	dihydrofolate synthase activity
NQZ91_RS08010	COG1363	Peptidase, m42
NQZ91_RS08020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NQZ91_RS08030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQZ91_RS08060	COG0459	protein refolding
NQZ91_RS08070	COG4667	esterase of the alpha-beta hydrolase superfamily
NQZ91_RS08095	COG4608	Belongs to the ABC transporter superfamily
NQZ91_RS08100	COG0601	transmembrane transport
NQZ91_RS08105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQZ91_RS08200	COG1473	amidohydrolase
NQZ91_RS08205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NQZ91_RS08210	COG0705	Rhomboid family
NQZ91_RS08215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NQZ91_RS08220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NQZ91_RS08230	COG1132	(ABC) transporter
NQZ91_RS08235	COG1132	(ABC) transporter
NQZ91_RS08245	COG0756	dUTP diphosphatase activity
NQZ91_RS08260	COG0584	glycerophosphoryl diester phosphodiesterase
NQZ91_RS08265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NQZ91_RS08270	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NQZ91_RS08310	COG2222	sugar isomerase
NQZ91_RS08315	COG2936	dipeptidyl-peptidase activity
NQZ91_RS08325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NQZ91_RS08335	COG2814	Major facilitator Superfamily
NQZ91_RS08345	COG1882	Formate acetyltransferase
NQZ91_RS08350	COG0366	Alpha amylase catalytic
NQZ91_RS08350	COG0366	Alpha amylase catalytic
NQZ91_RS08375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NQZ91_RS08380	COG0681	Belongs to the peptidase S26 family
NQZ91_RS08400	COG0366	Alpha amylase catalytic
NQZ91_RS08410	COG2188	Transcriptional regulator
NQZ91_RS08425	COG1193	negative regulation of DNA recombination
NQZ91_RS08430	COG0456	acetyltransferase
NQZ91_RS08440	COG0656	L-ascorbic acid biosynthetic process
NQZ91_RS08445	COG3118	belongs to the thioredoxin family
NQZ91_RS08455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NQZ91_RS08455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NQZ91_RS08460	COG1115	amino acid carrier protein
NQZ91_RS08465	COG0668	transmembrane transport
NQZ91_RS08485	COG0564	pseudouridine synthase activity
NQZ91_RS08490	COG0492	ferredoxin-NADP+ reductase activity
NQZ91_RS08495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NQZ91_RS08500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NQZ91_RS08515	COG0803	Belongs to the bacterial solute-binding protein 9 family
NQZ91_RS08525	COG3343	RNA polymerase activity
NQZ91_RS08530	COG0504	CTP synthase activity
NQZ91_RS08545	COG0191	fructose-bisphosphate aldolase activity
NQZ91_RS08550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NQZ91_RS08560	COG1461	Dihydroxyacetone kinase
NQZ91_RS08570	COG0629	single-stranded DNA binding
NQZ91_RS08575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NQZ91_RS08595	COG4555	ABC transporter
NQZ91_RS08600	COG4152	abc transporter atp-binding protein
NQZ91_RS08605	COG1668	transmembrane transport
NQZ91_RS08640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NQZ91_RS08655	COG0006	proline dipeptidase activity
NQZ91_RS08670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NQZ91_RS08675	COG1609	Transcriptional regulator
NQZ91_RS08680	COG1621	beta-fructofuranosidase activity
NQZ91_RS08685	COG2190	(PTS) system
NQZ91_RS08685	COG1263	PTS System
NQZ91_RS08685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQZ91_RS08690	COG1940	carbohydrate kinase activity
NQZ91_RS08695	COG1482	cell wall glycoprotein biosynthetic process
NQZ91_RS08700	COG0653	protein targeting
NQZ91_RS08705	COG0736	holo-[acyl-carrier-protein] synthase activity
NQZ91_RS08710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NQZ91_RS08725	COG3684	Belongs to the aldolase LacD family
NQZ91_RS08735	COG2151	metal-sulfur cluster biosynthetic enzyme
NQZ91_RS08740	COG3547	Transposase (IS116 IS110 IS902 family)
NQZ91_RS08760	COG0129	dihydroxy-acid dehydratase activity
NQZ91_RS08775	COG0463	Glycosyl transferase, family 2
NQZ91_RS08780	COG0028	Belongs to the TPP enzyme family
NQZ91_RS08785	COG0440	acetolactate synthase activity
NQZ91_RS08790	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NQZ91_RS08795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NQZ91_RS08815	COG1126	abc transporter atp-binding protein
NQZ91_RS08820	COG0765	amino acid transport
NQZ91_RS08825	COG1968	undecaprenyl-diphosphatase activity
NQZ91_RS08830	COG4862	establishment of competence for transformation
NQZ91_RS08835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NQZ91_RS08845	COG0719	Fe-S assembly protein
NQZ91_RS08850	COG0454	-acetyltransferase
NQZ91_RS08855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NQZ91_RS08880	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NQZ91_RS08885	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NQZ91_RS08890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NQZ91_RS08895	COG0560	Phosphoserine phosphatase
NQZ91_RS08905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NQZ91_RS08910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NQZ91_RS08915	COG0107	imidazoleglycerol-phosphate synthase activity
NQZ91_RS08935	COG0252	asparaginase activity
NQZ91_RS08950	COG0436	Aminotransferase
NQZ91_RS08955	COG0527	aspartate kinase activity
NQZ91_RS08960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQZ91_RS08965	COG1024	Enoyl-CoA hydratase
NQZ91_RS08975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NQZ91_RS08990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NQZ91_RS08995	COG1028	Short-chain dehydrogenase reductase Sdr
NQZ91_RS09015	COG0439	Biotin carboxylase
NQZ91_RS09055	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NQZ91_RS09065	COG3177	Filamentation induced by cAMP protein fic
NQZ91_RS09095	COG3716	PTS system mannose fructose sorbose family IID component
NQZ91_RS09100	COG3715	PTS system
NQZ91_RS09110	COG0561	phosphatase activity
NQZ91_RS09115	COG2252	PERMEase
NQZ91_RS09120	COG0802	atpase or kinase
NQZ91_RS09125	COG1247	-acetyltransferase
NQZ91_RS09130	COG1316	TRANSCRIPTIONal
NQZ91_RS09140	COG0537	adenosine 5'-monophosphoramidase activity
NQZ91_RS09145	COG1131	(ABC) transporter
NQZ91_RS09150	COG4473	ABC transporter
NQZ91_RS09160	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NQZ91_RS09170	COG0195	Participates in both transcription termination and antitermination
NQZ91_RS09175	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NQZ91_RS09185	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NQZ91_RS09190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NQZ91_RS09195	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NQZ91_RS09200	COG1335	isochorismatase
NQZ91_RS09205	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NQZ91_RS09210	COG0154	amidase activity
NQZ91_RS09215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NQZ91_RS09220	COG0513	Belongs to the DEAD box helicase family
NQZ91_RS09230	COG0492	ferredoxin-NADP+ reductase activity
NQZ91_RS09245	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NQZ91_RS09255	COG0628	permease
NQZ91_RS09260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NQZ91_RS09270	COG1484	DNA-dependent DNA replication
NQZ91_RS09280	COG1160	GTP binding
NQZ91_RS09360	COG1609	Transcriptional regulator
NQZ91_RS09365	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NQZ91_RS09370	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NQZ91_RS09380	COG3142	Participates in the control of copper homeostasis
NQZ91_RS09390	COG2860	membrane
NQZ91_RS09395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NQZ91_RS09400	COG0022	dehydrogenase e1 component
NQZ91_RS09400	COG0508	dehydrogenase complex catalyzes the overall conversion of
NQZ91_RS09405	COG0508	dehydrogenase complex catalyzes the overall conversion of
NQZ91_RS09420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NQZ91_RS09425	COG0512	Glutamine amidotransferase of anthranilate synthase
NQZ91_RS09440	COG0135	phosphoribosylanthranilate isomerase activity
NQZ91_RS09445	COG0133	tryptophan synthase activity
NQZ91_RS09450	COG0159	tryptophan synthase activity
NQZ91_RS09460	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NQZ91_RS09470	COG1534	Rna-binding protein
NQZ91_RS09475	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NQZ91_RS09480	COG1713	HD superfamily hydrolase involved in NAD metabolism
NQZ91_RS09490	COG1335	isochorismatase
NQZ91_RS09495	COG0799	negative regulation of ribosome biogenesis
NQZ91_RS09500	COG2226	methyltransferase
NQZ91_RS09520	COG0789	Transcriptional regulator
NQZ91_RS09530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NQZ91_RS09550	COG0242	peptide deformylase activity
NQZ91_RS09560	COG1640	4-alpha-glucanotransferase
NQZ91_RS09565	COG0058	SHG alpha-glucan phosphorylase activity
NQZ91_RS09570	COG4175	Glycine betaine
NQZ91_RS09570	COG3448	diguanylate cyclase activity
NQZ91_RS09580	COG1472	Belongs to the glycosyl hydrolase 3 family
NQZ91_RS09595	COG1263	PTS System
NQZ91_RS09595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQZ91_RS09595	COG2190	(PTS) system
NQZ91_RS09600	COG0217	transcriptional regulatory protein
NQZ91_RS09610	COG1252	NADH dehydrogenase
NQZ91_RS09615	COG0142	geranyltranstransferase activity
NQZ91_RS09620	COG4939	FMN-binding domain protein
NQZ91_RS09645	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NQZ91_RS09650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NQZ91_RS09665	COG2188	Transcriptional regulator
NQZ91_RS09675	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQZ91_RS09685	COG3716	PTS system mannose fructose sorbose family IID component
NQZ91_RS09695	COG2017	converts alpha-aldose to the beta-anomer
NQZ91_RS09710	COG0346	lactoylglutathione lyase activity
NQZ91_RS09715	COG3586	endonuclease activity
NQZ91_RS09720	COG0525	valine-tRNA ligase activity
NQZ91_RS09745	COG1122	ATPase activity
NQZ91_RS09755	COG0357	Ribosomal RNA small subunit methyltransferase G
NQZ91_RS09760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NQZ91_RS09765	COG3331	DNA recombination
NQZ91_RS09770	COG4474	Belongs to the UPF0398 family
NQZ91_RS09775	COG3599	regulation of cell shape
NQZ91_RS09785	COG0116	Belongs to the methyltransferase superfamily
NQZ91_RS09800	COG1854	S-ribosylhomocysteine lyase activity
NQZ91_RS09805	COG1418	mRNA catabolic process
NQZ91_RS09815	COG1758	RNA polymerase activity
NQZ91_RS09820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NQZ91_RS09825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NQZ91_RS09830	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NQZ91_RS09830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NQZ91_RS09835	COG0631	protein serine/threonine phosphatase activity
NQZ91_RS09840	COG0515	serine threonine protein kinase
NQZ91_RS09840	COG2815	serine threonine protein kinase
NQZ91_RS09855	COG4585	Histidine kinase
NQZ91_RS09870	COG1185	polyribonucleotide nucleotidyltransferase activity
NQZ91_RS09885	COG1739	Uncharacterized protein family UPF0029
NQZ91_RS09890	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NQZ91_RS09895	COG1040	competence protein
NQZ91_RS09910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NQZ91_RS09920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NQZ91_RS09955	COG3425	synthase
NQZ91_RS09960	COG0183	Belongs to the thiolase family
NQZ91_RS09980	COG0726	polysaccharide deacetylase
NQZ91_RS09985	COG1486	melibiose metabolic process
NQZ91_RS09990	COG2723	6-phospho-beta-galactosidase activity
NQZ91_RS10000	COG3711	transcriptional antiterminator
NQZ91_RS10015	COG1447	Phosphotransferase system cellobiose-specific component IIA
NQZ91_RS10025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NQZ91_RS10030	COG0513	Belongs to the DEAD box helicase family
NQZ91_RS10045	COG1695	Transcriptional regulator
NQZ91_RS10055	COG1956	GAF domain-containing protein
NQZ91_RS10060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NQZ91_RS10080	COG1363	Peptidase, m42
NQZ91_RS10090	COG2131	deaminase
NQZ91_RS10095	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NQZ91_RS10100	COG2249	NAD(P)H dehydrogenase (quinone) activity
NQZ91_RS10105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NQZ91_RS10130	COG2246	polysaccharide biosynthetic process
NQZ91_RS10135	COG4708	membrane
NQZ91_RS10140	COG2183	response to ionizing radiation
NQZ91_RS10145	COG3091	SprT-like family
NQZ91_RS10155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NQZ91_RS10160	COG0534	Mate efflux family protein
NQZ91_RS10165	COG0569	domain protein
NQZ91_RS10170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NQZ91_RS10175	COG2502	aspartate--ammonia ligase
NQZ91_RS10180	COG1217	gtp-binding protein TYPA
NQZ91_RS10190	COG0668	transmembrane transport
NQZ91_RS10200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NQZ91_RS10205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NQZ91_RS10220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NQZ91_RS10225	COG1799	cell septum assembly
NQZ91_RS10240	COG3599	regulation of cell shape
NQZ91_RS10265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQZ91_RS10270	COG0542	response to heat
NQZ91_RS10275	COG4703	Protein of unknown function (DUF1797)
NQZ91_RS10280	COG0765	amino acid transport
NQZ91_RS10290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NQZ91_RS10295	COG2321	neutral zinc metallopeptidase
NQZ91_RS10305	COG1722	exodeoxyribonuclease VII activity
NQZ91_RS10315	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NQZ91_RS10320	COG1438	arginine binding
NQZ91_RS10325	COG0497	DNA recombination
NQZ91_RS10335	COG1307	EDD domain protein, DegV family
NQZ91_RS10340	COG2755	lipolytic protein G-D-S-L family
NQZ91_RS10350	COG0776	regulation of translation
NQZ91_RS10360	COG1254	Belongs to the acylphosphatase family
NQZ91_RS10365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQZ91_RS10385	COG3763	UPF0154 protein
NQZ91_RS10390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NQZ91_RS10410	COG0582	viral genome integration into host DNA
NQZ91_RS10415	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NQZ91_RS10420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NQZ91_RS10425	COG1187	pseudouridine synthase activity
NQZ91_RS10430	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NQZ91_RS10445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NQZ91_RS10450	COG0671	phosphoesterase, PA-phosphatase related
NQZ91_RS10455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NQZ91_RS10455	COG2755	lipolytic protein G-D-S-L family
NQZ91_RS10465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQZ91_RS10485	COG1131	(ABC) transporter
NQZ91_RS10490	COG0842	Transport permease protein
NQZ91_RS10495	COG4585	Histidine kinase
NQZ91_RS10500	COG2197	response regulator
NQZ91_RS10505	COG4483	Protein conserved in bacteria
NQZ91_RS10510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NQZ91_RS10525	COG0742	ribosomal rna small subunit methyltransferase
NQZ91_RS10530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NQZ91_RS10535	COG3480	Lon protease (S16) C-terminal proteolytic domain
NQZ91_RS10540	COG4470	Protein conserved in bacteria
NQZ91_RS10555	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NQZ91_RS10560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NQZ91_RS10565	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NQZ91_RS10580	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NQZ91_RS10585	COG0025	NhaP-type Na H and K H
NQZ91_RS10590	COG1119	ATPase activity
NQZ91_RS10595	COG1253	flavin adenine dinucleotide binding
NQZ91_RS10605	COG0335	large ribosomal subunit rRNA binding
NQZ91_RS10610	COG0513	Belongs to the DEAD box helicase family
NQZ91_RS10625	COG2827	Endonuclease containing a URI domain
NQZ91_RS10630	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NQZ91_RS10640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NQZ91_RS10660	COG1131	(ABC) transporter
NQZ91_RS10685	COG1131	(ABC) transporter
NQZ91_RS10700	COG1136	(ABC) transporter
NQZ91_RS10710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NQZ91_RS10710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NQZ91_RS10725	COG1832	CoA-binding protein
NQZ91_RS10735	COG0343	queuine tRNA-ribosyltransferase activity
NQZ91_RS10740	COG0006	proline dipeptidase activity
NQZ91_RS10745	COG1609	Transcriptional regulator
NQZ91_RS10760	COG0038	chloride channel
NQZ91_RS10770	COG0716	FMN binding
NQZ91_RS10775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NQZ91_RS10785	COG0254	rRNA binding
NQZ91_RS10790	COG0772	Belongs to the SEDS family
NQZ91_RS10795	COG0693	protein deglycase activity
NQZ91_RS10800	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NQZ91_RS10810	COG1393	Belongs to the ArsC family
NQZ91_RS10815	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NQZ91_RS10820	COG0813	purine-nucleoside phosphorylase activity
NQZ91_RS10830	COG0058	SHG alpha-glucan phosphorylase activity
NQZ91_RS10840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NQZ91_RS10880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NQZ91_RS10885	COG2274	protein secretion by the type I secretion system
NQZ91_RS10945	COG3290	protein histidine kinase activity
NQZ91_RS10965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NQZ91_RS11035	COG2274	protein secretion by the type I secretion system