locus-tag	class	description
JZ789_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JZ789_RS00010	COG0592	DNA-directed DNA polymerase activity
JZ789_RS00030	COG0012	GTP binding
JZ789_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
JZ789_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JZ789_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JZ789_RS00060	COG0037	tRNA processing
JZ789_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JZ789_RS00180	COG1792	Involved in formation and maintenance of cell shape
JZ789_RS00195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JZ789_RS00200	COG0436	Aminotransferase
JZ789_RS00205	COG1381	Involved in DNA repair and RecF pathway recombination
JZ789_RS00210	COG0416	fatty acid biosynthetic process
JZ789_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JZ789_RS00225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JZ789_RS00240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JZ789_RS00245	COG0138	bifunctional purine biosynthesis protein purh
JZ789_RS00280	COG0151	Belongs to the GarS family
JZ789_RS00285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JZ789_RS00300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JZ789_RS00330	COG1131	(ABC) transporter
JZ789_RS00340	COG1132	(ABC) transporter
JZ789_RS00350	COG2255	four-way junction helicase activity
JZ789_RS00355	COG0546	phosphoglycolate phosphatase activity
JZ789_RS00375	COG0285	dihydrofolate synthase activity
JZ789_RS00385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JZ789_RS00390	COG0632	four-way junction helicase activity
JZ789_RS00395	COG0519	Catalyzes the synthesis of GMP from XMP
JZ789_RS00410	COG1393	Belongs to the ArsC family
JZ789_RS00415	COG4472	Bacterial protein of unknown function (DUF965)
JZ789_RS00420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JZ789_RS00425	COG3906	Belongs to the UPF0473 family
JZ789_RS00430	COG0051	transcription antitermination factor activity, RNA binding
JZ789_RS00435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JZ789_RS00440	COG0088	Forms part of the polypeptide exit tunnel
JZ789_RS00445	COG0089	rRNA binding
JZ789_RS00450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JZ789_RS00455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JZ789_RS00460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JZ789_RS00465	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JZ789_RS00470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JZ789_RS00475	COG0255	Belongs to the universal ribosomal protein uL29 family
JZ789_RS00480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JZ789_RS00485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JZ789_RS00490	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JZ789_RS00495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JZ789_RS00500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JZ789_RS00505	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JZ789_RS00510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JZ789_RS00515	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JZ789_RS00520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JZ789_RS00525	COG1841	ribosomal large subunit assembly
JZ789_RS00535	COG0201	protein transport
JZ789_RS00540	COG0563	adenylate kinase activity
JZ789_RS00545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JZ789_RS00550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JZ789_RS00555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JZ789_RS00565	COG0202	RNA polymerase activity
JZ789_RS00670	COG0582	viral genome integration into host DNA
JZ789_RS00680	COG2946	Replication initiation factor
JZ789_RS00725	COG1121	(ABC) transporter
JZ789_RS00730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JZ789_RS00735	COG3443	Belongs to the bacterial solute-binding protein 9 family
JZ789_RS00735	COG0803	Belongs to the bacterial solute-binding protein 9 family
JZ789_RS00760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JZ789_RS00765	COG0085	RNA polymerase activity
JZ789_RS00770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JZ789_RS00780	COG1619	proteins homologs of microcin C7 resistance protein MccF
JZ789_RS00785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JZ789_RS00790	COG1459	type II secretion system
JZ789_RS00795	COG4537	Required for transformation and DNA binding
JZ789_RS00825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JZ789_RS00835	COG0285	dihydrofolate synthase activity
JZ789_RS00840	COG1363	Peptidase, m42
JZ789_RS00850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JZ789_RS00860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JZ789_RS00885	COG0459	protein refolding
JZ789_RS00895	COG0049	tRNA binding
JZ789_RS00900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JZ789_RS00905	COG3590	peptidase
JZ789_RS00915	COG0126	phosphoglycerate kinase activity
JZ789_RS00925	COG0789	Transcriptional regulator
JZ789_RS00930	COG0174	glutamine synthetase
JZ789_RS00945	COG1214	PFAM Peptidase M22, glycoprotease
JZ789_RS00955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JZ789_RS00960	COG2207	Transcriptional regulator
JZ789_RS00970	COG1175	transmembrane transport
JZ789_RS00975	COG0395	ABC-type sugar transport system, permease component
JZ789_RS01015	COG1131	(ABC) transporter
JZ789_RS01020	COG2081	HI0933 family
JZ789_RS01025	COG2723	6-phospho-beta-galactosidase activity
JZ789_RS01035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JZ789_RS01050	COG3959	Transketolase, thiamine diphosphate binding domain
JZ789_RS01055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JZ789_RS01060	COG0584	glycerophosphoryl diester phosphodiesterase
JZ789_RS01065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JZ789_RS01070	COG2222	sugar isomerase
JZ789_RS01075	COG0582	viral genome integration into host DNA
JZ789_RS01080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JZ789_RS01180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JZ789_RS01190	COG1882	Formate acetyltransferase
JZ789_RS01205	COG2910	NAD(P)H-binding
JZ789_RS01230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JZ789_RS01265	COG0363	glucosamine-6-phosphate deaminase activity
JZ789_RS01270	COG2217	Heavy metal translocating P-type atpase
JZ789_RS01275	COG2217	Heavy metal translocating P-type atpase
JZ789_RS01285	COG2217	Heavy metal translocating P-type atpase
JZ789_RS01290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JZ789_RS01295	COG0681	Belongs to the peptidase S26 family
JZ789_RS01315	COG0366	Alpha amylase catalytic
JZ789_RS01320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ789_RS01320	COG1263	PTS System
JZ789_RS01325	COG2188	Transcriptional regulator
JZ789_RS01340	COG1193	negative regulation of DNA recombination
JZ789_RS01350	COG3118	belongs to the thioredoxin family
JZ789_RS01360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JZ789_RS01360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JZ789_RS01390	COG1115	amino acid carrier protein
JZ789_RS01395	COG0668	transmembrane transport
JZ789_RS01405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JZ789_RS01415	COG0167	dihydroorotate dehydrogenase activity
JZ789_RS01425	COG0561	phosphatase activity
JZ789_RS01440	COG1131	(ABC) transporter
JZ789_RS01445	COG1309	transcriptional regulator
JZ789_RS01450	COG1511	domain protein
JZ789_RS01475	COG1346	cytolysis
JZ789_RS01480	COG2116	formate transmembrane transporter activity
JZ789_RS01485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JZ789_RS01490	COG0433	COG0433 Predicted ATPase
JZ789_RS01495	COG0494	nUDIX hydrolase
JZ789_RS01515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JZ789_RS01520	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JZ789_RS01530	COG0124	histidyl-tRNA synthetase
JZ789_RS01535	COG1064	alcohol dehydrogenase
JZ789_RS01540	COG1454	alcohol dehydrogenase
JZ789_RS01540	COG1012	belongs to the aldehyde dehydrogenase family
JZ789_RS01550	COG4988	ABC transporter
JZ789_RS01555	COG1132	(ABC) transporter
JZ789_RS01570	COG1129	ABC transporter
JZ789_RS01575	COG0534	Mate efflux family protein
JZ789_RS01580	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JZ789_RS01595	COG1304	FMN binding
JZ789_RS01600	COG1132	(ABC) transporter
JZ789_RS01605	COG1132	(ABC) transporter
JZ789_RS01610	COG3830	Belongs to the UPF0237 family
JZ789_RS01615	COG2848	UPF0210 protein
JZ789_RS01620	COG0588	phosphoglycerate mutase activity
JZ789_RS01625	COG1420	regulation of RNA biosynthetic process
JZ789_RS01630	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JZ789_RS01635	COG0443	Heat shock 70 kDa protein
JZ789_RS01640	COG0484	heat shock protein binding
JZ789_RS01645	COG0095	Lipoate-protein ligase
JZ789_RS01655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JZ789_RS01660	COG0765	amino acid transport
JZ789_RS01675	COG3655	Transcriptional regulator
JZ789_RS01685	COG2217	Heavy metal translocating P-type atpase
JZ789_RS01700	COG0351	phosphomethylpyrimidine kinase
JZ789_RS01710	COG4475	Protein of unknown function (DUF436)
JZ789_RS01740	COG4221	oxidoreductase activity
JZ789_RS01745	COG0446	pyridine nucleotide-disulphide oxidoreductase
JZ789_RS01745	COG1902	pentaerythritol trinitrate reductase activity
JZ789_RS01750	COG2910	NAD(P)H-binding
JZ789_RS01755	COG1959	2 iron, 2 sulfur cluster binding
JZ789_RS01775	COG0544	peptidyl-prolyl cis-trans isomerase activity
JZ789_RS01795	COG3343	RNA polymerase activity
JZ789_RS01800	COG0504	CTP synthase activity
JZ789_RS01810	COG0191	fructose-bisphosphate aldolase activity
JZ789_RS01815	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JZ789_RS01890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JZ789_RS01895	COG2137	regulation of response to DNA damage stimulus
JZ789_RS01905	COG0765	amino acid transport
JZ789_RS01910	COG1126	abc transporter atp-binding protein
JZ789_RS01915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JZ789_RS01945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JZ789_RS01950	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JZ789_RS01955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JZ789_RS01970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JZ789_RS01975	COG3022	response to hydroperoxide
JZ789_RS01980	COG1316	TRANSCRIPTIONal
JZ789_RS01985	COG3944	biosynthesis protein
JZ789_RS01995	COG4464	protein tyrosine phosphatase activity
JZ789_RS02005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JZ789_RS02010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JZ789_RS02015	COG1215	transferase activity, transferring glycosyl groups
JZ789_RS02060	COG4372	Transposase
JZ789_RS02085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JZ789_RS02105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JZ789_RS02110	COG0077	Prephenate dehydratase
JZ789_RS02120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JZ789_RS02135	COG0270	DNA (cytosine-5-)-methyltransferase activity
JZ789_RS02200	COG3942	CHAP domain
JZ789_RS02200	COG1705	Flagellar rod assembly protein muramidase FlgJ
JZ789_RS02305	COG1475	DNA binding
JZ789_RS02310	COG4443	Transcriptional Coactivator p15 (PC4)
JZ789_RS02345	COG1192	Involved in chromosome partitioning
JZ789_RS02375	COG1396	sequence-specific DNA binding
JZ789_RS02380	COG0542	response to heat
JZ789_RS02400	COG3843	relaxase mobilization nuclease domain protein
JZ789_RS02415	COG0105	UTP biosynthetic process
JZ789_RS02420	COG2226	methyltransferase
JZ789_RS02475	COG4555	ABC transporter
JZ789_RS02545	COG0647	UMP catabolic process
JZ789_RS02555	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JZ789_RS02560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JZ789_RS02565	COG1970	mechanosensitive ion channel activity
JZ789_RS02570	COG0358	DNA primase activity
JZ789_RS02575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JZ789_RS02580	COG2151	metal-sulfur cluster biosynthetic enzyme
JZ789_RS02640	COG3561	AntA/AntB antirepressor
JZ789_RS02760	COG5484	DNA packaging
JZ789_RS02760	COG3728	DNA packaging
JZ789_RS02930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JZ789_RS02940	COG1131	(ABC) transporter
JZ789_RS02945	COG2188	Transcriptional regulator
JZ789_RS02955	COG0205	6-phosphofructokinase activity
JZ789_RS02960	COG0469	pyruvate kinase activity
JZ789_RS02970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JZ789_RS02975	COG0657	acetylesterase activity
JZ789_RS02975	COG2755	lipolytic protein G-D-S-L family
JZ789_RS02990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JZ789_RS03005	COG1307	EDD domain protein, DegV family
JZ789_RS03010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JZ789_RS03015	COG0617	tRNA 3'-terminal CCA addition
JZ789_RS03020	COG0488	(ABC) transporter
JZ789_RS03030	COG1940	carbohydrate kinase activity
JZ789_RS03045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JZ789_RS03050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JZ789_RS03060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JZ789_RS03075	COG0481	GTPase activity
JZ789_RS03105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JZ789_RS03110	COG2890	protein-(glutamine-N5) methyltransferase activity
JZ789_RS03115	COG0009	L-threonylcarbamoyladenylate synthase
JZ789_RS03125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JZ789_RS03135	COG0741	lytic transglycosylase activity
JZ789_RS03140	COG4221	oxidoreductase activity
JZ789_RS03165	COG1401	restriction endodeoxyribonuclease activity
JZ789_RS03170	COG4268	DNA restriction-modification system
JZ789_RS03180	COG2188	Transcriptional regulator
JZ789_RS03185	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JZ789_RS03190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JZ789_RS03210	COG4974	Belongs to the 'phage' integrase family
JZ789_RS03225	COG0745	RESPONSE REGULATOR receiver
JZ789_RS03245	COG1136	(ABC) transporter
JZ789_RS03285	COG2382	esterase
JZ789_RS03300	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JZ789_RS03315	COG0222	ribosome binding
JZ789_RS03320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JZ789_RS03325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JZ789_RS03330	COG0758	DNA mediated transformation
JZ789_RS03340	COG0425	Belongs to the sulfur carrier protein TusA family
JZ789_RS03340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JZ789_RS03350	COG1272	protein, Hemolysin III
JZ789_RS03360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JZ789_RS03365	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JZ789_RS03370	COG0582	viral genome integration into host DNA
JZ789_RS03380	COG1396	sequence-specific DNA binding
JZ789_RS03390	COG1940	carbohydrate kinase activity
JZ789_RS03410	COG1175	transmembrane transport
JZ789_RS03430	COG4806	L-rhamnose isomerase
JZ789_RS03430	COG1070	Carbohydrate kinase
JZ789_RS03490	COG2190	(PTS) system
JZ789_RS03490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ789_RS03490	COG1263	PTS System
JZ789_RS03560	COG1705	Flagellar rod assembly protein muramidase FlgJ
JZ789_RS03560	COG3942	CHAP domain
JZ789_RS03605	COG1484	DNA-dependent DNA replication
JZ789_RS03630	COG1131	(ABC) transporter
JZ789_RS03655	COG1396	sequence-specific DNA binding
JZ789_RS03700	COG0424	maF-like protein
JZ789_RS03705	COG0737	Belongs to the 5'-nucleotidase family
JZ789_RS03715	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JZ789_RS03720	COG0463	Glycosyl transferase, family 2
JZ789_RS03730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JZ789_RS03735	COG0284	orotidine-5'-phosphate decarboxylase activity
JZ789_RS03740	COG0167	dihydroorotate dehydrogenase activity
JZ789_RS03765	COG0297	glycogen (starch) synthase activity
JZ789_RS03775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JZ789_RS03790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JZ789_RS03845	COG3843	relaxase mobilization nuclease domain protein
JZ789_RS04035	COG0270	DNA (cytosine-5-)-methyltransferase activity
JZ789_RS04080	COG1126	abc transporter atp-binding protein
JZ789_RS04090	COG0488	(ABC) transporter
JZ789_RS04180	COG3716	PTS system mannose fructose sorbose family IID component
JZ789_RS04190	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ789_RS04210	COG1070	Carbohydrate kinase
JZ789_RS04250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JZ789_RS04250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JZ789_RS04260	COG3711	transcriptional antiterminator
JZ789_RS04270	COG3684	Belongs to the aldolase LacD family
JZ789_RS04275	COG1105	Belongs to the carbohydrate kinase PfkB family
JZ789_RS04280	COG0698	ribose 5-phosphate isomerase
JZ789_RS04285	COG0698	ribose 5-phosphate isomerase
JZ789_RS04290	COG1349	DNA-binding transcription factor activity
JZ789_RS04325	COG1194	a g-specific adenine glycosylase
JZ789_RS04335	COG1132	(ABC) transporter
JZ789_RS04340	COG1132	(ABC) transporter
JZ789_RS04345	COG0280	phosphate acetyltransferase
JZ789_RS04350	COG0564	pseudouridine synthase activity
JZ789_RS04355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JZ789_RS04360	COG2357	RelA SpoT domain protein
JZ789_RS04365	COG4116	CYTH
JZ789_RS04375	COG1104	cysteine desulfurase activity
JZ789_RS04390	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JZ789_RS04395	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JZ789_RS04405	COG3764	Sortase (surface protein transpeptidase)
JZ789_RS04410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JZ789_RS04415	COG0039	L-malate dehydrogenase activity
JZ789_RS04420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JZ789_RS04425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JZ789_RS04430	COG1079	Belongs to the binding-protein-dependent transport system permease family
JZ789_RS04435	COG4603	Belongs to the binding-protein-dependent transport system permease family
JZ789_RS04440	COG3845	ABC transporter
JZ789_RS04445	COG1744	ABC transporter substrate-binding protein PnrA-like
JZ789_RS04460	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JZ789_RS04465	COG2813	Specifically methylates the guanine in position
JZ789_RS04470	COG1072	(Pantothenic acid kinase))
JZ789_RS04475	COG0268	Binds directly to 16S ribosomal RNA
JZ789_RS04485	COG5002	protein histidine kinase activity
JZ789_RS04490	COG0745	RESPONSE REGULATOR receiver
JZ789_RS04500	COG0704	Plays a role in the regulation of phosphate uptake
JZ789_RS04505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JZ789_RS04510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JZ789_RS04515	COG0581	inorganic phosphate transmembrane transporter activity
JZ789_RS04520	COG0573	inorganic phosphate transmembrane transporter activity
JZ789_RS04530	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JZ789_RS04530	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JZ789_RS04535	COG0483	inositol monophosphate 1-phosphatase activity
JZ789_RS04540	COG4476	Belongs to the UPF0223 family
JZ789_RS04545	COG1393	Belongs to the ArsC family
JZ789_RS04550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JZ789_RS04555	COG0196	riboflavin kinase activity
JZ789_RS04560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JZ789_RS04600	COG0561	phosphatase activity
JZ789_RS04605	COG2195	Cleaves the N-terminal amino acid of tripeptides
JZ789_RS04620	COG1695	Transcriptional regulator
JZ789_RS04645	COG3759	membrane
JZ789_RS04650	COG1846	Transcriptional regulator
JZ789_RS04665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JZ789_RS04670	COG2610	gluconate transmembrane transporter activity
JZ789_RS04690	COG0302	gtp cyclohydrolase
JZ789_RS04695	COG1051	belongs to the nudix hydrolase family
JZ789_RS04750	COG1028	Short-chain dehydrogenase reductase Sdr
JZ789_RS04755	COG1312	Catalyzes the dehydration of D-mannonate
JZ789_RS04765	COG0800	Aldolase
JZ789_RS04775	COG3250	beta-galactosidase activity
JZ789_RS04785	COG2211	Major facilitator Superfamily
JZ789_RS04800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JZ789_RS04810	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JZ789_RS04815	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JZ789_RS04820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JZ789_RS04825	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JZ789_RS04830	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JZ789_RS04835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JZ789_RS04840	COG0356	it plays a direct role in the translocation of protons across the membrane
JZ789_RS04850	COG1597	lipid kinase activity
JZ789_RS04865	COG0701	Predicted permease
JZ789_RS04870	COG3689	TIGRFAM TIGR03943 family protein
JZ789_RS04875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JZ789_RS04890	COG0552	protein localization to endoplasmic reticulum
JZ789_RS04895	COG0561	phosphatase activity
JZ789_RS04900	COG0561	phosphatase activity
JZ789_RS04905	COG1196	nuclear chromosome segregation
JZ789_RS04950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JZ789_RS04955	COG0538	isocitrate dehydrogenase activity
JZ789_RS04960	COG0372	Belongs to the citrate synthase family
JZ789_RS04965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JZ789_RS04970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JZ789_RS04975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JZ789_RS04980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JZ789_RS04985	COG1609	Transcriptional regulator
JZ789_RS04995	COG5492	domain, Protein
JZ789_RS05005	COG3716	PTS system mannose fructose sorbose family IID component
JZ789_RS05015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ789_RS05020	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JZ789_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
JZ789_RS05075	COG1476	TRANSCRIPTIONal
JZ789_RS05100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JZ789_RS05110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JZ789_RS05115	COG4122	O-methyltransferase activity
JZ789_RS05140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JZ789_RS05140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JZ789_RS05150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JZ789_RS05155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JZ789_RS05165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JZ789_RS05170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JZ789_RS05170	COG1116	anion transmembrane transporter activity
JZ789_RS05175	COG4120	Belongs to the binding-protein-dependent transport system permease family
JZ789_RS05190	COG3684	Belongs to the aldolase LacD family
JZ789_RS05200	COG3679	Belongs to the UPF0342 family
JZ789_RS05205	COG0287	Prephenate dehydrogenase
JZ789_RS05210	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JZ789_RS05215	COG0710	3-dehydroquinate dehydratase activity
JZ789_RS05220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JZ789_RS05225	COG1368	sulfuric ester hydrolase activity
JZ789_RS05240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JZ789_RS05250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JZ789_RS05280	COG1216	Glycosyl transferase, family 2
JZ789_RS05295	COG1442	glycosyl transferase family 8
JZ789_RS05295	COG1216	Glycosyl transferase, family 2
JZ789_RS05300	COG1442	glycosyl transferase family 8
JZ789_RS05330	COG1216	Glycosyl transferase, family 2
JZ789_RS05330	COG1442	glycosyl transferase family 8
JZ789_RS05360	COG1091	dTDP-4-dehydrorhamnose reductase activity
JZ789_RS05365	COG1088	dTDP-glucose 4,6-dehydratase activity
JZ789_RS05380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JZ789_RS05390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JZ789_RS05395	COG2384	SAM-dependent methyltransferase
JZ789_RS05410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JZ789_RS05420	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JZ789_RS05420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JZ789_RS05425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JZ789_RS05435	COG0300	oxidoreductase activity
JZ789_RS05440	COG1234	tRNA 3'-trailer cleavage
JZ789_RS05450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JZ789_RS05455	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JZ789_RS05465	COG2807	transmembrane transport
JZ789_RS05470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JZ789_RS05480	COG1702	phosphate starvation-inducible protein PhoH
JZ789_RS05485	COG4479	Belongs to the UPF0346 family
JZ789_RS05500	COG2996	Protein conserved in bacteria
JZ789_RS05505	COG0233	cytoplasmic translational termination
JZ789_RS05510	COG0528	UMP kinase activity
JZ789_RS05515	COG2244	polysaccharide biosynthetic process
JZ789_RS05520	COG0625	glutathione transferase activity
JZ789_RS05545	COG0346	lactoylglutathione lyase activity
JZ789_RS05550	COG0697	spore germination
JZ789_RS05550	COG1674	ftsk spoiiie
JZ789_RS05555	COG1621	beta-fructofuranosidase activity
JZ789_RS05560	COG1653	transport
JZ789_RS05565	COG0395	ABC-type sugar transport system, permease component
JZ789_RS05570	COG4209	transmembrane transport
JZ789_RS05575	COG1609	Transcriptional regulator
JZ789_RS05595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JZ789_RS05605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JZ789_RS05615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JZ789_RS05625	COG1181	Belongs to the D-alanine--D-alanine ligase family
JZ789_RS05630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JZ789_RS05635	COG0768	penicillin binding
JZ789_RS05640	COG0488	(ABC) transporter
JZ789_RS05645	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JZ789_RS05655	COG0745	RESPONSE REGULATOR receiver
JZ789_RS05665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JZ789_RS05670	COG0765	amino acid transport
JZ789_RS05675	COG0765	amino acid transport
JZ789_RS05680	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JZ789_RS05695	COG0438	transferase activity, transferring glycosyl groups
JZ789_RS05710	COG1609	Transcriptional regulator
JZ789_RS05720	COG0343	queuine tRNA-ribosyltransferase activity
JZ789_RS05730	COG1832	CoA-binding protein
JZ789_RS05740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JZ789_RS05740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JZ789_RS05760	COG1136	(ABC) transporter
JZ789_RS05770	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JZ789_RS05775	COG2217	Heavy metal translocating P-type atpase
JZ789_RS05790	COG1063	alcohol dehydrogenase
JZ789_RS05795	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JZ789_RS05800	COG0557	exoribonuclease II activity
JZ789_RS05810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JZ789_RS05815	COG2814	Major facilitator Superfamily
JZ789_RS05825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JZ789_RS05830	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JZ789_RS05835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JZ789_RS05845	COG1737	Transcriptional regulator
JZ789_RS05855	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JZ789_RS05865	COG1011	Hydrolase
JZ789_RS05870	COG1132	(ABC) transporter
JZ789_RS05875	COG1132	(ABC) transporter
JZ789_RS05895	COG2177	Part of the ABC transporter FtsEX involved in
JZ789_RS05900	COG2884	Cell division ATP-binding protein ftsE
JZ789_RS05910	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JZ789_RS05945	COG1078	dGTPase activity
JZ789_RS05960	COG0149	triose-phosphate isomerase activity
JZ789_RS05965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JZ789_RS05980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JZ789_RS05985	COG0772	Belongs to the SEDS family
JZ789_RS06005	COG3859	Proton-coupled thiamine transporter YuaJ
JZ789_RS06015	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JZ789_RS06025	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JZ789_RS06035	COG0577	efflux transmembrane transporter activity
JZ789_RS06040	COG1136	(ABC) transporter
JZ789_RS06045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JZ789_RS06055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JZ789_RS06065	COG1268	BioY protein
JZ789_RS06070	COG4443	Transcriptional Coactivator p15 (PC4)
JZ789_RS06080	COG0826	peptidase U32
JZ789_RS06095	COG0789	Transcriptional regulator
JZ789_RS06130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JZ789_RS06140	COG0765	amino acid transport
JZ789_RS06145	COG4703	Protein of unknown function (DUF1797)
JZ789_RS06150	COG0542	response to heat
JZ789_RS06155	COG0494	nUDIX hydrolase
JZ789_RS06155	COG0406	alpha-ribazole phosphatase activity
JZ789_RS06175	COG3599	regulation of cell shape
JZ789_RS06190	COG1799	cell septum assembly
JZ789_RS06200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JZ789_RS06215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JZ789_RS06250	COG0681	Belongs to the peptidase S26 family
JZ789_RS06270	COG1217	gtp-binding protein TYPA
JZ789_RS06325	COG0525	valine-tRNA ligase activity
JZ789_RS06335	COG0346	lactoylglutathione lyase activity
JZ789_RS06350	COG2017	converts alpha-aldose to the beta-anomer
JZ789_RS06360	COG3716	PTS system mannose fructose sorbose family IID component
JZ789_RS06370	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ789_RS06380	COG2188	Transcriptional regulator
JZ789_RS06385	COG2188	Transcriptional regulator
JZ789_RS06395	COG3557	Belongs to the UPF0374 family
JZ789_RS06405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JZ789_RS06405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JZ789_RS06405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JZ789_RS06410	COG1105	Belongs to the carbohydrate kinase PfkB family
JZ789_RS06415	COG1349	DNA-binding transcription factor activity
JZ789_RS06420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JZ789_RS06425	COG0336	Belongs to the RNA methyltransferase TrmD family
JZ789_RS06430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JZ789_RS06435	COG0534	Mate efflux family protein
JZ789_RS06445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JZ789_RS06450	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JZ789_RS06465	COG1177	transmembrane transport
JZ789_RS06470	COG1176	ABC-type spermidine putrescine transport system, permease component I
JZ789_RS06475	COG3842	ATPase activity
JZ789_RS06480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JZ789_RS06485	COG0083	homoserine kinase activity
JZ789_RS06490	COG0460	homoserine dehydrogenase
JZ789_RS06495	COG0726	polysaccharide deacetylase
JZ789_RS06500	COG1132	(ABC) transporter
JZ789_RS06515	COG0228	four-way junction DNA binding
JZ789_RS06525	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JZ789_RS06530	COG2136	Putative SAM-dependent methyltransferase
JZ789_RS06530	COG2521	methyltransferase
JZ789_RS06540	COG0505	Belongs to the CarA family
JZ789_RS06545	COG0540	Belongs to the ATCase OTCase family
JZ789_RS06550	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JZ789_RS06560	COG2824	Alkylphosphonate utilization operon protein PhnA
JZ789_RS06565	COG0564	pseudouridine synthase activity
JZ789_RS06580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JZ789_RS06585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JZ789_RS06590	COG1114	Component of the transport system for branched-chain amino acids
JZ789_RS06595	COG0301	tRNA thio-modification
JZ789_RS06600	COG1104	cysteine desulfurase activity
JZ789_RS06625	COG0539	negative regulation of cytoplasmic translation
JZ789_RS06645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JZ789_RS06655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JZ789_RS06670	COG2184	nucleotidyltransferase activity
JZ789_RS06675	COG0187	DNA topoisomerase II activity
JZ789_RS06685	COG1074	ATP-dependent DNA helicase activity
JZ789_RS06690	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JZ789_RS06720	COG1131	(ABC) transporter
JZ789_RS06750	COG1011	Hydrolase
JZ789_RS06755	COG1122	ATPase activity
JZ789_RS06760	COG1122	ATPase activity
JZ789_RS06775	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JZ789_RS06800	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JZ789_RS06815	COG0210	DNA helicase
JZ789_RS06820	COG3177	Filamentation induced by cAMP protein fic
JZ789_RS06835	COG1164	Oligoendopeptidase f
JZ789_RS06845	COG0346	lactoylglutathione lyase activity
JZ789_RS06850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JZ789_RS06855	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JZ789_RS06860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JZ789_RS06870	COG0446	pyridine nucleotide-disulphide oxidoreductase
JZ789_RS06875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JZ789_RS06880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JZ789_RS06920	COG0732	type I restriction modification DNA specificity domain
JZ789_RS06935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JZ789_RS06940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JZ789_RS06950	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JZ789_RS06960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JZ789_RS06965	COG4684	Psort location CytoplasmicMembrane, score
JZ789_RS06970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JZ789_RS07015	COG0531	amino acid
JZ789_RS07025	COG0708	Exodeoxyribonuclease III
JZ789_RS07035	COG1393	Belongs to the ArsC family
JZ789_RS07040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JZ789_RS07045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JZ789_RS07055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JZ789_RS07065	COG4467	Involved in initiation control of chromosome replication
JZ789_RS07070	COG0470	DNA polymerase III
JZ789_RS07075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JZ789_RS07080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JZ789_RS07095	COG0517	IMP dehydrogenase activity
JZ789_RS07105	COG2333	competence protein COMEC
JZ789_RS07105	COG0658	competence protein
JZ789_RS07110	COG1596	polysaccharide export
JZ789_RS07110	COG1555	photosystem II stabilization
JZ789_RS07115	COG0204	Acyl-transferase
JZ789_RS07120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JZ789_RS07125	COG1120	ATPase activity
JZ789_RS07130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JZ789_RS07135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JZ789_RS07140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JZ789_RS07145	COG0386	Belongs to the glutathione peroxidase family
JZ789_RS07150	COG1187	pseudouridine synthase activity
JZ789_RS07155	COG0435	Glutathione S-transferase
JZ789_RS07175	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JZ789_RS07180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JZ789_RS07230	COG0363	glucosamine-6-phosphate deaminase activity
JZ789_RS07235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JZ789_RS07240	COG1438	arginine binding
JZ789_RS07255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JZ789_RS07260	COG1288	antiporter activity
JZ789_RS07265	COG0549	Belongs to the carbamate kinase family
JZ789_RS07270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JZ789_RS07275	COG0454	-acetyltransferase
JZ789_RS07290	COG1481	regulation of sporulation
JZ789_RS07295	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JZ789_RS07300	COG1660	Displays ATPase and GTPase activities
JZ789_RS07305	COG0251	oxidation-reduction process
JZ789_RS07310	COG0534	Mate efflux family protein
JZ789_RS07320	COG0436	Aminotransferase
JZ789_RS07335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JZ789_RS07340	COG0562	UDP-galactopyranose mutase
JZ789_RS07360	COG1396	sequence-specific DNA binding
JZ789_RS07375	COG2723	6-phospho-beta-galactosidase activity
JZ789_RS07385	COG1447	Phosphotransferase system cellobiose-specific component IIA
JZ789_RS07395	COG1105	Belongs to the carbohydrate kinase PfkB family
JZ789_RS07400	COG0698	ribose 5-phosphate isomerase
JZ789_RS07405	COG0698	ribose 5-phosphate isomerase
JZ789_RS07410	COG1940	carbohydrate kinase activity
JZ789_RS07425	COG3843	relaxase mobilization nuclease domain protein
JZ789_RS07550	COG0463	Glycosyl transferase, family 2
JZ789_RS07635	COG0270	DNA (cytosine-5-)-methyltransferase activity
JZ789_RS07660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JZ789_RS07670	COG0058	SHG alpha-glucan phosphorylase activity
JZ789_RS07675	COG0813	purine-nucleoside phosphorylase activity
JZ789_RS07680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JZ789_RS07690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JZ789_RS07695	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JZ789_RS07700	COG0732	type I restriction modification DNA specificity domain
JZ789_RS07705	COG0732	type I restriction modification DNA specificity domain
JZ789_RS07720	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JZ789_RS07735	COG2268	Band 7 protein
JZ789_RS07740	COG1704	LemA family
JZ789_RS07750	COG1573	uracil-dna glycosylase
JZ789_RS07780	COG2226	methyltransferase
JZ789_RS07785	COG0488	(ABC) transporter
JZ789_RS07790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JZ789_RS07805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JZ789_RS07810	COG3442	glutamine amidotransferase
JZ789_RS07815	COG2226	methyltransferase
JZ789_RS07825	COG0488	(ABC) transporter
JZ789_RS07860	COG3842	ATPase activity
JZ789_RS07880	COG1263	PTS System
JZ789_RS07880	COG2190	(PTS) system
JZ789_RS07880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ789_RS07885	COG3711	transcriptional antiterminator
JZ789_RS07890	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JZ789_RS07895	COG3527	Alpha-acetolactate decarboxylase
JZ789_RS07905	COG0628	permease
JZ789_RS07910	COG2706	6-phosphogluconolactonase activity
JZ789_RS07920	COG1011	Hydrolase
JZ789_RS07945	COG0560	Phosphoserine phosphatase
JZ789_RS07950	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JZ789_RS07955	COG0187	DNA topoisomerase II activity
JZ789_RS07960	COG0693	protein deglycase activity
JZ789_RS07965	COG0772	Belongs to the SEDS family
JZ789_RS07980	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JZ789_RS07985	COG0716	FMN binding
JZ789_RS07995	COG0287	Prephenate dehydrogenase
JZ789_RS07995	COG1605	Chorismate mutase
JZ789_RS08000	COG0038	chloride channel
JZ789_RS08230	COG3561	AntA/AntB antirepressor
JZ789_RS08280	COG0737	Belongs to the 5'-nucleotidase family
JZ789_RS08285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JZ789_RS08290	COG1466	dna polymerase III delta subunit
JZ789_RS08325	COG0683	leucine binding
JZ789_RS08340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JZ789_RS08345	COG0366	Alpha amylase catalytic
JZ789_RS08355	COG0395	ABC-type sugar transport system, permease component
JZ789_RS08360	COG1175	transmembrane transport
JZ789_RS08365	COG1653	transport
JZ789_RS08375	COG2207	Transcriptional regulator
JZ789_RS08380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JZ789_RS08385	COG0626	cystathionine gamma-synthase activity
JZ789_RS08400	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JZ789_RS08405	COG2827	Endonuclease containing a URI domain
JZ789_RS08430	COG0640	Transcriptional regulator
JZ789_RS08435	COG0513	Belongs to the DEAD box helicase family
JZ789_RS08440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JZ789_RS08480	COG0494	nUDIX hydrolase
JZ789_RS08485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JZ789_RS08500	COG1028	Short-chain dehydrogenase reductase Sdr
JZ789_RS08530	COG0577	efflux transmembrane transporter activity
JZ789_RS08535	COG1136	(ABC) transporter
JZ789_RS08540	COG2205	protein histidine kinase activity
JZ789_RS08545	COG0745	RESPONSE REGULATOR receiver
JZ789_RS08555	COG0436	Aminotransferase
JZ789_RS08565	COG1174	glycine betaine transport
JZ789_RS08570	COG0517	IMP dehydrogenase activity
JZ789_RS08570	COG1125	glycine betaine transport
JZ789_RS08590	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JZ789_RS08595	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JZ789_RS08600	COG1482	cell wall glycoprotein biosynthetic process
JZ789_RS08615	COG3091	SprT-like family
JZ789_RS08620	COG2183	response to ionizing radiation
JZ789_RS08625	COG0656	L-ascorbic acid biosynthetic process
JZ789_RS08630	COG4708	membrane
JZ789_RS08635	COG2246	polysaccharide biosynthetic process
JZ789_RS08645	COG0024	Methionine aminopeptidase
JZ789_RS08655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JZ789_RS08660	COG2249	NAD(P)H dehydrogenase (quinone) activity
JZ789_RS08665	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JZ789_RS08670	COG2131	deaminase
JZ789_RS08680	COG1363	Peptidase, m42
JZ789_RS08695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JZ789_RS08700	COG1956	GAF domain-containing protein
JZ789_RS08710	COG1695	Transcriptional regulator
JZ789_RS08720	COG0673	inositol 2-dehydrogenase activity
JZ789_RS08725	COG0513	Belongs to the DEAD box helicase family
JZ789_RS08730	COG0726	polysaccharide deacetylase
JZ789_RS08745	COG0183	Belongs to the thiolase family
JZ789_RS08750	COG3425	synthase
JZ789_RS08765	COG0776	regulation of translation
JZ789_RS08775	COG2755	lipolytic protein G-D-S-L family
JZ789_RS08780	COG1307	EDD domain protein, DegV family
JZ789_RS08785	COG0497	DNA recombination
JZ789_RS08790	COG1438	arginine binding
JZ789_RS08795	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JZ789_RS08805	COG1722	exodeoxyribonuclease VII activity
JZ789_RS08810	COG1570	exodeoxyribonuclease VII activity
JZ789_RS08815	COG2321	neutral zinc metallopeptidase
JZ789_RS08820	COG1755	Isoprenylcysteine carboxyl methyltransferase
JZ789_RS08825	COG5002	protein histidine kinase activity
JZ789_RS08830	COG0745	RESPONSE REGULATOR receiver
JZ789_RS08855	COG1227	inorganic diphosphatase activity
JZ789_RS08865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JZ789_RS08870	COG1253	flavin adenine dinucleotide binding
JZ789_RS08875	COG1119	ATPase activity
JZ789_RS08880	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JZ789_RS08885	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JZ789_RS08890	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JZ789_RS08895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JZ789_RS08910	COG4470	Protein conserved in bacteria
JZ789_RS08915	COG3480	Lon protease (S16) C-terminal proteolytic domain
JZ789_RS08920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JZ789_RS08925	COG0742	ribosomal rna small subunit methyltransferase
JZ789_RS08935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JZ789_RS08940	COG4483	Protein conserved in bacteria
JZ789_RS08945	COG2197	response regulator
JZ789_RS08950	COG4585	Histidine kinase
JZ789_RS08955	COG0842	Transport permease protein
JZ789_RS08960	COG1131	(ABC) transporter
JZ789_RS08975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JZ789_RS08985	COG2755	lipolytic protein G-D-S-L family
JZ789_RS08985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JZ789_RS08990	COG0671	phosphoesterase, PA-phosphatase related
JZ789_RS08995	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JZ789_RS09005	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JZ789_RS09010	COG1187	pseudouridine synthase activity
JZ789_RS09015	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JZ789_RS09020	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JZ789_RS09025	COG0582	viral genome integration into host DNA
JZ789_RS09045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JZ789_RS09050	COG3763	UPF0154 protein
JZ789_RS09060	COG3579	cysteine-type endopeptidase activity
JZ789_RS09080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JZ789_RS09085	COG1254	Belongs to the acylphosphatase family
JZ789_RS09095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JZ789_RS09100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JZ789_RS09110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JZ789_RS09120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JZ789_RS09130	COG1160	GTP binding
JZ789_RS09140	COG1484	DNA-dependent DNA replication
JZ789_RS09150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JZ789_RS09155	COG0628	permease
JZ789_RS09160	COG0745	RESPONSE REGULATOR receiver
JZ789_RS09165	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JZ789_RS09175	COG0492	ferredoxin-NADP+ reductase activity
JZ789_RS09185	COG0513	Belongs to the DEAD box helicase family
JZ789_RS09200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JZ789_RS09205	COG0768	penicillin binding
JZ789_RS09215	COG0275	rRNA processing
JZ789_RS09260	COG4939	FMN-binding domain protein
JZ789_RS09265	COG0142	geranyltranstransferase activity
JZ789_RS09270	COG1252	NADH dehydrogenase
JZ789_RS09280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JZ789_RS09285	COG0569	domain protein
JZ789_RS09290	COG0534	Mate efflux family protein
JZ789_RS09300	COG4224	UPF0291 protein
JZ789_RS09305	COG0751	glycine-tRNA ligase activity
JZ789_RS09330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JZ789_RS09335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JZ789_RS09340	COG1464	Belongs to the NlpA lipoprotein family
JZ789_RS09345	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JZ789_RS09350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JZ789_RS09355	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JZ789_RS09365	COG2252	PERMEase
JZ789_RS09370	COG0561	phosphatase activity
JZ789_RS09380	COG3715	PTS system
JZ789_RS09385	COG3716	PTS system mannose fructose sorbose family IID component
JZ789_RS09415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JZ789_RS09460	COG0439	Biotin carboxylase
JZ789_RS09480	COG1028	Short-chain dehydrogenase reductase Sdr
JZ789_RS09485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JZ789_RS09490	COG2070	2-Nitropropane dioxygenase
JZ789_RS09500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JZ789_RS09510	COG1024	Enoyl-CoA hydratase
JZ789_RS09515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JZ789_RS09520	COG0527	aspartate kinase activity
JZ789_RS09525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JZ789_RS09530	COG0736	holo-[acyl-carrier-protein] synthase activity
JZ789_RS09535	COG0653	protein targeting
JZ789_RS09545	COG1940	carbohydrate kinase activity
JZ789_RS09550	COG2190	(PTS) system
JZ789_RS09550	COG1263	PTS System
JZ789_RS09550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ789_RS09555	COG1621	beta-fructofuranosidase activity
JZ789_RS09560	COG1609	Transcriptional regulator
JZ789_RS09565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JZ789_RS09580	COG0006	proline dipeptidase activity
JZ789_RS09585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JZ789_RS09600	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JZ789_RS09605	COG0629	single-stranded DNA binding
JZ789_RS09615	COG0095	Lipoate-protein ligase
JZ789_RS09620	COG2723	6-phospho-beta-galactosidase activity
JZ789_RS09635	COG2723	6-phospho-beta-galactosidase activity
JZ789_RS09640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JZ789_RS09650	COG1447	Phosphotransferase system cellobiose-specific component IIA
JZ789_RS09655	COG3711	transcriptional antiterminator
JZ789_RS09655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JZ789_RS09670	COG4095	Psort location CytoplasmicMembrane, score
JZ789_RS09675	COG2723	6-phospho-beta-galactosidase activity
JZ789_RS09680	COG0346	lactoylglutathione lyase activity
JZ789_RS09685	COG2723	6-phospho-beta-galactosidase activity
JZ789_RS09690	COG2207	Transcriptional regulator
JZ789_RS09705	COG2190	(PTS) system
JZ789_RS09705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ789_RS09705	COG1263	PTS System
JZ789_RS09725	COG0508	dehydrogenase complex catalyzes the overall conversion of
JZ789_RS09730	COG0022	dehydrogenase e1 component
JZ789_RS09730	COG0508	dehydrogenase complex catalyzes the overall conversion of
JZ789_RS09735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JZ789_RS09740	COG2860	membrane
JZ789_RS09755	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JZ789_RS09760	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JZ789_RS09770	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JZ789_RS09775	COG0195	Participates in both transcription termination and antitermination
JZ789_RS09785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JZ789_RS09795	COG4473	ABC transporter
JZ789_RS09800	COG1131	(ABC) transporter
JZ789_RS09805	COG0537	adenosine 5'-monophosphoramidase activity
JZ789_RS09815	COG1316	TRANSCRIPTIONal
JZ789_RS09825	COG0802	atpase or kinase
JZ789_RS09840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JZ789_RS09845	COG0601	transmembrane transport
JZ789_RS09850	COG4608	Belongs to the ABC transporter superfamily
JZ789_RS09865	COG1686	Belongs to the peptidase S11 family
JZ789_RS09880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JZ789_RS09885	COG0719	Fe-S assembly protein
JZ789_RS09895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JZ789_RS09900	COG4862	establishment of competence for transformation
JZ789_RS09905	COG1968	undecaprenyl-diphosphatase activity
JZ789_RS09910	COG0765	amino acid transport
JZ789_RS09930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JZ789_RS09935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JZ789_RS09940	COG0440	acetolactate synthase activity
JZ789_RS09945	COG0028	Belongs to the TPP enzyme family
JZ789_RS09950	COG0463	Glycosyl transferase, family 2
JZ789_RS09965	COG0129	dihydroxy-acid dehydratase activity
JZ789_RS09975	COG2151	metal-sulfur cluster biosynthetic enzyme
JZ789_RS10060	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JZ789_RS10075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JZ789_RS10090	COG3842	ATPase activity
JZ789_RS10100	COG2207	Transcriptional regulator
JZ789_RS10100	COG4753	response regulator
JZ789_RS10105	COG2972	Histidine kinase
JZ789_RS10120	COG1653	transport
JZ789_RS10125	COG0395	ABC-type sugar transport system, permease component
JZ789_RS10130	COG1175	transmembrane transport
JZ789_RS10145	COG0383	alpha-mannosidase activity
JZ789_RS10165	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JZ789_RS10185	COG1045	serine acetyltransferase
JZ789_RS10190	COG1185	polyribonucleotide nucleotidyltransferase activity
JZ789_RS10195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JZ789_RS10200	COG1131	(ABC) transporter
JZ789_RS10235	COG0335	large ribosomal subunit rRNA binding
JZ789_RS10240	COG1335	isochorismatase
JZ789_RS10245	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JZ789_RS10250	COG0436	Aminotransferase
JZ789_RS10255	COG0589	response to stress
JZ789_RS10270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JZ789_RS10315	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JZ789_RS10320	COG1739	Uncharacterized protein family UPF0029
JZ789_RS10330	COG1098	S1 RNA binding domain
JZ789_RS10355	COG0515	serine threonine protein kinase
JZ789_RS10355	COG2815	serine threonine protein kinase
JZ789_RS10360	COG0631	protein serine/threonine phosphatase activity
JZ789_RS10365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JZ789_RS10365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JZ789_RS10370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JZ789_RS10375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JZ789_RS10380	COG1758	RNA polymerase activity
JZ789_RS10390	COG1418	mRNA catabolic process
JZ789_RS10395	COG1854	S-ribosylhomocysteine lyase activity
JZ789_RS10405	COG0116	Belongs to the methyltransferase superfamily
JZ789_RS10415	COG3599	regulation of cell shape
JZ789_RS10420	COG4474	Belongs to the UPF0398 family
JZ789_RS10425	COG3331	DNA recombination
JZ789_RS10430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JZ789_RS10435	COG0357	Ribosomal RNA small subunit methyltransferase G
JZ789_RS10450	COG1122	ATPase activity
JZ789_RS10460	COG1054	Belongs to the UPF0176 family
JZ789_RS10470	COG4720	Psort location CytoplasmicMembrane, score
JZ789_RS10480	COG0217	transcriptional regulatory protein
JZ789_RS10495	COG2190	(PTS) system
JZ789_RS10495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JZ789_RS10495	COG1263	PTS System
JZ789_RS10510	COG0058	SHG alpha-glucan phosphorylase activity
JZ789_RS10515	COG1640	4-alpha-glucanotransferase
JZ789_RS10525	COG0242	peptide deformylase activity
JZ789_RS10535	COG2348	transferase activity, transferring amino-acyl groups
JZ789_RS10540	COG0789	Transcriptional regulator
JZ789_RS10575	COG2226	methyltransferase
JZ789_RS10580	COG0799	negative regulation of ribosome biogenesis
JZ789_RS10585	COG1335	isochorismatase
JZ789_RS10600	COG1713	HD superfamily hydrolase involved in NAD metabolism
JZ789_RS10605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JZ789_RS10610	COG1534	Rna-binding protein
JZ789_RS10615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JZ789_RS10630	COG3142	Participates in the control of copper homeostasis
JZ789_RS10645	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JZ789_RS10650	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JZ789_RS10655	COG1609	Transcriptional regulator
JZ789_RS10665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JZ789_RS10670	COG0154	amidase activity
JZ789_RS10675	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JZ789_RS10705	COG1187	pseudouridine synthase activity
JZ789_RS10720	COG0242	peptide deformylase activity
JZ789_RS10730	COG0066	3-isopropylmalate dehydratase activity
JZ789_RS10755	COG2309	aminopeptidase activity
JZ789_RS10765	COG2176	DNA-directed DNA polymerase activity
JZ789_RS10770	COG2376	Dihydroxyacetone kinase
JZ789_RS10780	COG2376	Dihydroxyacetone kinase
JZ789_RS10785	COG1461	Dihydroxyacetone kinase
JZ789_RS10790	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JZ789_RS10795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JZ789_RS10800	COG0442	prolyl-tRNA aminoacylation
JZ789_RS10810	COG4589	Belongs to the CDS family
JZ789_RS10815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JZ789_RS10820	COG1862	Preprotein translocase
JZ789_RS10830	COG2918	glutathione biosynthetic process
JZ789_RS10830	COG1181	Belongs to the D-alanine--D-alanine ligase family
JZ789_RS10840	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JZ789_RS10845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JZ789_RS10850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JZ789_RS10855	COG0542	response to heat
JZ789_RS10860	COG4463	regulation of RNA biosynthetic process
JZ789_RS10870	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JZ789_RS10900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JZ789_RS10905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JZ789_RS10910	COG0492	ferredoxin-NADP+ reductase activity
JZ789_RS10915	COG0564	pseudouridine synthase activity
JZ789_RS10920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JZ789_RS10940	COG1564	THIamine pyrophosphokinase
JZ789_RS10950	COG1162	GTPase activity
JZ789_RS10960	COG1132	(ABC) transporter
JZ789_RS10985	COG4115	mRNA cleavage
JZ789_RS11010	COG0084	hydrolase, TatD family'
JZ789_RS11020	COG1847	R3H domain protein
JZ789_RS11030	COG0594	ribonuclease P activity
JZ789_RS11035	COG0165	Argininosuccinate lyase
JZ789_RS11040	COG0137	argininosuccinate synthase activity
JZ789_RS11050	COG1827	regulation of RNA biosynthetic process
JZ789_RS11065	COG2040	homocysteine
JZ789_RS11115	COG0756	dUTP diphosphatase activity
JZ789_RS11120	COG0582	viral genome integration into host DNA
JZ789_RS11195	COG1132	(ABC) transporter
JZ789_RS11200	COG1132	(ABC) transporter
JZ789_RS11210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JZ789_RS11215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JZ789_RS11220	COG0705	Rhomboid family
JZ789_RS11225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JZ789_RS11230	COG1473	amidohydrolase
JZ789_RS11235	COG2171	N-acyltransferase activity
JZ789_RS11240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JZ789_RS11270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JZ789_RS11295	COG3623	hexulose-6-phosphate isomerase
JZ789_RS11320	COG1523	belongs to the glycosyl hydrolase 13 family
JZ789_RS11325	COG1609	Transcriptional regulator
JZ789_RS11330	COG1126	abc transporter atp-binding protein
JZ789_RS11335	COG0765	amino acid transport
JZ789_RS11340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JZ789_RS11350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JZ789_RS11360	COG1447	Phosphotransferase system cellobiose-specific component IIA
JZ789_RS11370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JZ789_RS11370	COG3711	transcriptional antiterminator
JZ789_RS11380	COG2723	6-phospho-beta-galactosidase activity
JZ789_RS11385	COG1486	melibiose metabolic process
JZ789_RS11395	COG3590	peptidase
JZ789_RS11400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JZ789_RS11405	COG1321	iron dependent repressor
JZ789_RS11405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JZ789_RS11410	COG1121	(ABC) transporter
JZ789_RS11415	COG0803	Belongs to the bacterial solute-binding protein 9 family
JZ789_RS11430	COG1490	D-aminoacyl-tRNA deacylase activity
JZ789_RS11440	COG0737	Belongs to the 5'-nucleotidase family
JZ789_RS11460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JZ789_RS11485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JZ789_RS11510	COG0737	Belongs to the 5'-nucleotidase family
JZ789_RS11515	COG1328	CTP reductase activity
JZ789_RS11520	COG1126	abc transporter atp-binding protein
JZ789_RS11530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JZ789_RS11535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JZ789_RS11550	COG1438	arginine binding
JZ789_RS11555	COG0018	arginyl-trna synthetase
JZ789_RS11575	COG1640	4-alpha-glucanotransferase
JZ789_RS11580	COG2182	Extracellular solute-binding protein
JZ789_RS11585	COG1175	transmembrane transport
JZ789_RS11590	COG3833	ABC-type maltose transport systems, permease component
JZ789_RS11595	COG5521	maltodextrose utilization protein MalA
JZ789_RS11600	COG1609	Transcriptional regulator
JZ789_RS11605	COG1523	belongs to the glycosyl hydrolase 13 family
JZ789_RS11610	COG1780	Probably involved in ribonucleotide reductase function
JZ789_RS11615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JZ789_RS11620	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JZ789_RS11625	COG2153	protein acetylation
JZ789_RS11630	COG4989	oxidoreductase activity
JZ789_RS11680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JZ789_RS11690	COG0305	Participates in initiation and elongation during chromosome replication
JZ789_RS11695	COG0359	binds to the 23S rRNA
JZ789_RS11705	COG0445	tRNA wobble uridine modification
JZ789_RS11715	COG1733	regulation of RNA biosynthetic process
JZ789_RS11725	COG0482	sulfurtransferase activity
JZ789_RS11730	COG1760	l-serine dehydratase
JZ789_RS11735	COG1760	l-serine dehydratase
JZ789_RS11745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JZ789_RS11750	COG1122	ATPase activity
JZ789_RS11755	COG1122	ATPase activity
JZ789_RS11760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JZ789_RS11765	COG1426	Protein conserved in bacteria
JZ789_RS11770	COG0612	Peptidase, M16
JZ789_RS11775	COG0612	Peptidase, M16
JZ789_RS11785	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JZ789_RS11790	COG0516	GMP reductase activity
JZ789_RS11790	COG0517	IMP dehydrogenase activity
JZ789_RS11800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JZ789_RS11805	COG0488	(ABC) transporter
JZ789_RS11835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JZ789_RS11840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JZ789_RS11845	COG1475	DNA binding
JZ789_RS11880	COG3583	domain protein