locus-tag	class	description
BFP66_RS00080	COG1792	Involved in formation and maintenance of cell shape
BFP66_RS00095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFP66_RS00100	COG0436	Aminotransferase
BFP66_RS00105	COG1381	Involved in DNA repair and RecF pathway recombination
BFP66_RS00110	COG0416	fatty acid biosynthetic process
BFP66_RS00115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFP66_RS00140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BFP66_RS00145	COG0138	bifunctional purine biosynthesis protein purh
BFP66_RS00160	COG0151	Belongs to the GarS family
BFP66_RS00165	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BFP66_RS00185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BFP66_RS00205	COG1131	(ABC) transporter
BFP66_RS00215	COG1132	(ABC) transporter
BFP66_RS00220	COG2255	four-way junction helicase activity
BFP66_RS00230	COG0546	phosphoglycolate phosphatase activity
BFP66_RS00240	COG0285	dihydrofolate synthase activity
BFP66_RS00255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFP66_RS00260	COG0632	four-way junction helicase activity
BFP66_RS00265	COG0519	Catalyzes the synthesis of GMP from XMP
BFP66_RS00280	COG1393	Belongs to the ArsC family
BFP66_RS00285	COG4472	Bacterial protein of unknown function (DUF965)
BFP66_RS00290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BFP66_RS00295	COG3906	Belongs to the UPF0473 family
BFP66_RS00300	COG0051	transcription antitermination factor activity, RNA binding
BFP66_RS00305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BFP66_RS00310	COG0088	Forms part of the polypeptide exit tunnel
BFP66_RS00315	COG0089	rRNA binding
BFP66_RS00320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BFP66_RS00325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BFP66_RS00330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BFP66_RS00335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BFP66_RS00340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BFP66_RS00345	COG0255	Belongs to the universal ribosomal protein uL29 family
BFP66_RS00350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BFP66_RS00355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BFP66_RS00360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BFP66_RS00365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BFP66_RS00370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BFP66_RS00375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BFP66_RS00385	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BFP66_RS00390	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BFP66_RS00395	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BFP66_RS00400	COG1841	ribosomal large subunit assembly
BFP66_RS00410	COG0201	protein transport
BFP66_RS00415	COG0563	adenylate kinase activity
BFP66_RS00420	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BFP66_RS00425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BFP66_RS00430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BFP66_RS00440	COG0202	RNA polymerase activity
BFP66_RS00580	COG2801	Transposase and inactivated derivatives
BFP66_RS00605	COG1121	(ABC) transporter
BFP66_RS00610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFP66_RS00615	COG0803	Belongs to the bacterial solute-binding protein 9 family
BFP66_RS00615	COG3443	Belongs to the bacterial solute-binding protein 9 family
BFP66_RS00640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFP66_RS00645	COG0085	RNA polymerase activity
BFP66_RS00650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFP66_RS00660	COG1619	proteins homologs of microcin C7 resistance protein MccF
BFP66_RS00665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFP66_RS00670	COG1459	type II secretion system
BFP66_RS00675	COG4537	Required for transformation and DNA binding
BFP66_RS00705	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BFP66_RS00715	COG0285	dihydrofolate synthase activity
BFP66_RS00720	COG1363	Peptidase, m42
BFP66_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFP66_RS00740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFP66_RS00765	COG0459	protein refolding
BFP66_RS00775	COG0049	tRNA binding
BFP66_RS00780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BFP66_RS00785	COG3590	peptidase
BFP66_RS00795	COG0126	phosphoglycerate kinase activity
BFP66_RS00805	COG0789	Transcriptional regulator
BFP66_RS00810	COG0174	glutamine synthetase
BFP66_RS00825	COG1214	PFAM Peptidase M22, glycoprotease
BFP66_RS00835	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BFP66_RS00840	COG2207	Transcriptional regulator
BFP66_RS00850	COG1175	transmembrane transport
BFP66_RS00855	COG0395	ABC-type sugar transport system, permease component
BFP66_RS00875	COG2855	membrane
BFP66_RS00885	COG1131	(ABC) transporter
BFP66_RS00895	COG2081	HI0933 family
BFP66_RS00900	COG2723	6-phospho-beta-galactosidase activity
BFP66_RS00910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFP66_RS00925	COG3959	Transketolase, thiamine diphosphate binding domain
BFP66_RS00930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BFP66_RS00935	COG0584	glycerophosphoryl diester phosphodiesterase
BFP66_RS00940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BFP66_RS00945	COG2222	sugar isomerase
BFP66_RS00975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BFP66_RS00985	COG3942	CHAP domain
BFP66_RS00990	COG1882	Formate acetyltransferase
BFP66_RS01005	COG2910	NAD(P)H-binding
BFP66_RS01020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BFP66_RS01025	COG0681	Belongs to the peptidase S26 family
BFP66_RS01045	COG0366	Alpha amylase catalytic
BFP66_RS01055	COG1263	PTS System
BFP66_RS01055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFP66_RS01060	COG2188	Transcriptional regulator
BFP66_RS01075	COG1193	negative regulation of DNA recombination
BFP66_RS01110	COG3118	belongs to the thioredoxin family
BFP66_RS01115	COG0318	PFAM AMP-dependent synthetase and ligase
BFP66_RS01120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFP66_RS01120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFP66_RS01145	COG1115	amino acid carrier protein
BFP66_RS01150	COG0668	transmembrane transport
BFP66_RS01165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BFP66_RS01175	COG0167	dihydroorotate dehydrogenase activity
BFP66_RS01180	COG2843	Capsule synthesis protein
BFP66_RS01185	COG0561	phosphatase activity
BFP66_RS01200	COG1131	(ABC) transporter
BFP66_RS01205	COG1309	transcriptional regulator
BFP66_RS01210	COG1511	domain protein
BFP66_RS01250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFP66_RS01255	COG0433	COG0433 Predicted ATPase
BFP66_RS01260	COG0494	nUDIX hydrolase
BFP66_RS01325	COG0701	Predicted permease
BFP66_RS01335	COG1393	Belongs to the ArsC family
BFP66_RS01355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BFP66_RS01360	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BFP66_RS01365	COG0124	histidyl-tRNA synthetase
BFP66_RS01370	COG1064	alcohol dehydrogenase
BFP66_RS01375	COG1012	belongs to the aldehyde dehydrogenase family
BFP66_RS01375	COG1454	alcohol dehydrogenase
BFP66_RS01385	COG4988	ABC transporter
BFP66_RS01390	COG1132	(ABC) transporter
BFP66_RS01405	COG1129	ABC transporter
BFP66_RS01410	COG0534	Mate efflux family protein
BFP66_RS01415	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BFP66_RS01430	COG1304	FMN binding
BFP66_RS01435	COG1132	(ABC) transporter
BFP66_RS01440	COG1132	(ABC) transporter
BFP66_RS01445	COG3830	Belongs to the UPF0237 family
BFP66_RS01450	COG2848	UPF0210 protein
BFP66_RS01455	COG0588	phosphoglycerate mutase activity
BFP66_RS01460	COG1420	regulation of RNA biosynthetic process
BFP66_RS01465	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BFP66_RS01470	COG0443	Heat shock 70 kDa protein
BFP66_RS01475	COG0484	heat shock protein binding
BFP66_RS01480	COG0095	Lipoate-protein ligase
BFP66_RS01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFP66_RS01520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFP66_RS01525	COG0765	amino acid transport
BFP66_RS01530	COG3655	Transcriptional regulator
BFP66_RS01540	COG2217	Heavy metal translocating P-type atpase
BFP66_RS01555	COG0351	phosphomethylpyrimidine kinase
BFP66_RS01565	COG4475	Protein of unknown function (DUF436)
BFP66_RS01595	COG1902	pentaerythritol trinitrate reductase activity
BFP66_RS01595	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFP66_RS01615	COG0544	peptidyl-prolyl cis-trans isomerase activity
BFP66_RS01640	COG2801	Transposase and inactivated derivatives
BFP66_RS01645	COG3343	RNA polymerase activity
BFP66_RS01650	COG0504	CTP synthase activity
BFP66_RS01665	COG0191	fructose-bisphosphate aldolase activity
BFP66_RS01670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BFP66_RS01710	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BFP66_RS01715	COG2801	Transposase and inactivated derivatives
BFP66_RS01750	COG0436	Aminotransferase
BFP66_RS01755	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BFP66_RS01760	COG1335	isochorismatase
BFP66_RS01765	COG0335	large ribosomal subunit rRNA binding
BFP66_RS01780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFP66_RS01785	COG0154	amidase activity
BFP66_RS01790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFP66_RS01795	COG1609	Transcriptional regulator
BFP66_RS01800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BFP66_RS01805	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BFP66_RS01815	COG3142	Participates in the control of copper homeostasis
BFP66_RS01830	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BFP66_RS01835	COG1534	Rna-binding protein
BFP66_RS01840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BFP66_RS01845	COG1713	HD superfamily hydrolase involved in NAD metabolism
BFP66_RS01855	COG1335	isochorismatase
BFP66_RS01860	COG0799	negative regulation of ribosome biogenesis
BFP66_RS01865	COG2226	methyltransferase
BFP66_RS01885	COG0242	peptide deformylase activity
BFP66_RS01895	COG1640	4-alpha-glucanotransferase
BFP66_RS01900	COG0058	SHG alpha-glucan phosphorylase activity
BFP66_RS01915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFP66_RS01915	COG1263	PTS System
BFP66_RS01915	COG2190	(PTS) system
BFP66_RS01920	COG0217	transcriptional regulatory protein
BFP66_RS01930	COG4720	Psort location CytoplasmicMembrane, score
BFP66_RS01940	COG1054	Belongs to the UPF0176 family
BFP66_RS01950	COG1122	ATPase activity
BFP66_RS01965	COG0357	Ribosomal RNA small subunit methyltransferase G
BFP66_RS01970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFP66_RS01975	COG3331	DNA recombination
BFP66_RS01980	COG4474	Belongs to the UPF0398 family
BFP66_RS01985	COG3599	regulation of cell shape
BFP66_RS01995	COG0116	Belongs to the methyltransferase superfamily
BFP66_RS02005	COG1854	S-ribosylhomocysteine lyase activity
BFP66_RS02010	COG1418	mRNA catabolic process
BFP66_RS02020	COG1758	RNA polymerase activity
BFP66_RS02025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BFP66_RS02030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFP66_RS02035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFP66_RS02035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFP66_RS02040	COG0631	protein serine/threonine phosphatase activity
BFP66_RS02045	COG2815	serine threonine protein kinase
BFP66_RS02045	COG0515	serine threonine protein kinase
BFP66_RS02070	COG1098	S1 RNA binding domain
BFP66_RS02080	COG1739	Uncharacterized protein family UPF0029
BFP66_RS02085	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BFP66_RS02175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFP66_RS02180	COG2137	regulation of response to DNA damage stimulus
BFP66_RS02185	COG3557	Belongs to the UPF0374 family
BFP66_RS02195	COG2188	Transcriptional regulator
BFP66_RS02200	COG2188	Transcriptional regulator
BFP66_RS02210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFP66_RS02220	COG3716	PTS system mannose fructose sorbose family IID component
BFP66_RS02230	COG2017	converts alpha-aldose to the beta-anomer
BFP66_RS02245	COG0346	lactoylglutathione lyase activity
BFP66_RS02275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFP66_RS02305	COG1217	gtp-binding protein TYPA
BFP66_RS02320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BFP66_RS02335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BFP66_RS02340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BFP66_RS02345	COG1799	cell septum assembly
BFP66_RS02360	COG3599	regulation of cell shape
BFP66_RS02380	COG0494	nUDIX hydrolase
BFP66_RS02380	COG0406	alpha-ribazole phosphatase activity
BFP66_RS02385	COG0542	response to heat
BFP66_RS02390	COG4703	Protein of unknown function (DUF1797)
BFP66_RS02395	COG0765	amino acid transport
BFP66_RS02410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFP66_RS02445	COG0789	Transcriptional regulator
BFP66_RS02460	COG0826	peptidase U32
BFP66_RS02470	COG4443	Transcriptional Coactivator p15 (PC4)
BFP66_RS02475	COG1268	BioY protein
BFP66_RS02480	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BFP66_RS02485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFP66_RS02490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFP66_RS02495	COG1136	(ABC) transporter
BFP66_RS02500	COG0577	efflux transmembrane transporter activity
BFP66_RS02525	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BFP66_RS02535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BFP66_RS02545	COG3859	Proton-coupled thiamine transporter YuaJ
BFP66_RS02565	COG0772	Belongs to the SEDS family
BFP66_RS02570	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BFP66_RS02585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFP66_RS02590	COG0149	triose-phosphate isomerase activity
BFP66_RS02600	COG1078	dGTPase activity
BFP66_RS02635	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BFP66_RS02640	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BFP66_RS02645	COG2884	Cell division ATP-binding protein ftsE
BFP66_RS02650	COG2177	Part of the ABC transporter FtsEX involved in
BFP66_RS02670	COG1132	(ABC) transporter
BFP66_RS02675	COG1132	(ABC) transporter
BFP66_RS02680	COG1011	Hydrolase
BFP66_RS02700	COG1737	Transcriptional regulator
BFP66_RS02710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BFP66_RS02715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BFP66_RS02720	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BFP66_RS02730	COG2814	Major facilitator Superfamily
BFP66_RS02735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BFP66_RS02745	COG0557	exoribonuclease II activity
BFP66_RS02750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BFP66_RS02765	COG1063	alcohol dehydrogenase
BFP66_RS02780	COG2217	Heavy metal translocating P-type atpase
BFP66_RS02785	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BFP66_RS02795	COG0577	efflux transmembrane transporter activity
BFP66_RS02795	COG1136	(ABC) transporter
BFP66_RS02810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFP66_RS02810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFP66_RS02820	COG1832	CoA-binding protein
BFP66_RS02830	COG0343	queuine tRNA-ribosyltransferase activity
BFP66_RS02845	COG1609	Transcriptional regulator
BFP66_RS02860	COG0438	transferase activity, transferring glycosyl groups
BFP66_RS02875	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BFP66_RS02880	COG0765	amino acid transport
BFP66_RS02885	COG0765	amino acid transport
BFP66_RS02890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFP66_RS02900	COG0745	RESPONSE REGULATOR receiver
BFP66_RS02910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BFP66_RS02915	COG0488	(ABC) transporter
BFP66_RS02920	COG0768	penicillin binding
BFP66_RS02925	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BFP66_RS02930	COG1181	Belongs to the D-alanine--D-alanine ligase family
BFP66_RS02950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BFP66_RS02960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BFP66_RS02970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFP66_RS02990	COG1609	Transcriptional regulator
BFP66_RS02995	COG4209	transmembrane transport
BFP66_RS03000	COG0395	ABC-type sugar transport system, permease component
BFP66_RS03010	COG1621	beta-fructofuranosidase activity
BFP66_RS03015	COG1674	ftsk spoiiie
BFP66_RS03015	COG0697	spore germination
BFP66_RS03020	COG0346	lactoylglutathione lyase activity
BFP66_RS03045	COG0625	glutathione transferase activity
BFP66_RS03050	COG2244	polysaccharide biosynthetic process
BFP66_RS03055	COG0528	UMP kinase activity
BFP66_RS03060	COG0233	cytoplasmic translational termination
BFP66_RS03065	COG2996	Protein conserved in bacteria
BFP66_RS03080	COG4479	Belongs to the UPF0346 family
BFP66_RS03085	COG1702	phosphate starvation-inducible protein PhoH
BFP66_RS03090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFP66_RS03095	COG2807	transmembrane transport
BFP66_RS03105	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BFP66_RS03110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BFP66_RS03120	COG1234	tRNA 3'-trailer cleavage
BFP66_RS03125	COG0300	oxidoreductase activity
BFP66_RS03135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFP66_RS03140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BFP66_RS03140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BFP66_RS03150	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFP66_RS03165	COG2384	SAM-dependent methyltransferase
BFP66_RS03170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFP66_RS03180	COG0640	Transcriptional regulator
BFP66_RS03200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BFP66_RS03210	COG0135	phosphoribosylanthranilate isomerase activity
BFP66_RS03215	COG1088	dTDP-glucose 4,6-dehydratase activity
BFP66_RS03220	COG1091	dTDP-4-dehydrorhamnose reductase activity
BFP66_RS03250	COG1215	transferase activity, transferring glycosyl groups
BFP66_RS03280	COG1442	glycosyl transferase family 8
BFP66_RS03285	COG1442	glycosyl transferase family 8
BFP66_RS03285	COG1216	Glycosyl transferase, family 2
BFP66_RS03300	COG1216	Glycosyl transferase, family 2
BFP66_RS03330	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BFP66_RS03340	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BFP66_RS03355	COG1368	sulfuric ester hydrolase activity
BFP66_RS03360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFP66_RS03365	COG0710	3-dehydroquinate dehydratase activity
BFP66_RS03370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BFP66_RS03375	COG0287	Prephenate dehydrogenase
BFP66_RS03380	COG3679	Belongs to the UPF0342 family
BFP66_RS03390	COG3684	Belongs to the aldolase LacD family
BFP66_RS03410	COG4120	Belongs to the binding-protein-dependent transport system permease family
BFP66_RS03415	COG1116	anion transmembrane transporter activity
BFP66_RS03415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFP66_RS03420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BFP66_RS03425	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BFP66_RS03430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFP66_RS03435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFP66_RS03445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFP66_RS03445	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFP66_RS03455	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
BFP66_RS03460	COG3620	sequence-specific DNA binding
BFP66_RS03480	COG4122	O-methyltransferase activity
BFP66_RS03485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFP66_RS03495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BFP66_RS03520	COG1476	TRANSCRIPTIONal
BFP66_RS03555	COG1028	Short-chain dehydrogenase reductase Sdr
BFP66_RS03580	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BFP66_RS03585	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFP66_RS03595	COG3716	PTS system mannose fructose sorbose family IID component
BFP66_RS03605	COG5492	domain, Protein
BFP66_RS03615	COG1609	Transcriptional regulator
BFP66_RS03620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFP66_RS03625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFP66_RS03630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BFP66_RS03635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BFP66_RS03640	COG0372	Belongs to the citrate synthase family
BFP66_RS03645	COG0538	isocitrate dehydrogenase activity
BFP66_RS03650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFP66_RS03685	COG1196	nuclear chromosome segregation
BFP66_RS03690	COG0561	phosphatase activity
BFP66_RS03695	COG0561	phosphatase activity
BFP66_RS03700	COG0552	protein localization to endoplasmic reticulum
BFP66_RS03715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BFP66_RS03720	COG3689	TIGRFAM TIGR03943 family protein
BFP66_RS03725	COG0701	Predicted permease
BFP66_RS03735	COG1597	lipid kinase activity
BFP66_RS03745	COG0356	it plays a direct role in the translocation of protons across the membrane
BFP66_RS03750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BFP66_RS03755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFP66_RS03760	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BFP66_RS03765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BFP66_RS03770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BFP66_RS03775	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BFP66_RS03785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFP66_RS03800	COG2211	Major facilitator Superfamily
BFP66_RS03810	COG3250	beta-galactosidase activity
BFP66_RS03820	COG0800	Aldolase
BFP66_RS03830	COG1312	Catalyzes the dehydration of D-mannonate
BFP66_RS03835	COG1028	Short-chain dehydrogenase reductase Sdr
BFP66_RS03865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFP66_RS03865	COG0072	phenylalanine-tRNA ligase activity
BFP66_RS03890	COG1051	belongs to the nudix hydrolase family
BFP66_RS03895	COG0302	gtp cyclohydrolase
BFP66_RS03915	COG2610	gluconate transmembrane transporter activity
BFP66_RS03920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BFP66_RS03935	COG1846	Transcriptional regulator
BFP66_RS03940	COG3759	membrane
BFP66_RS03975	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFP66_RS03980	COG0561	phosphatase activity
BFP66_RS04015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BFP66_RS04020	COG0196	riboflavin kinase activity
BFP66_RS04025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFP66_RS04030	COG1393	Belongs to the ArsC family
BFP66_RS04035	COG4476	Belongs to the UPF0223 family
BFP66_RS04040	COG0483	inositol monophosphate 1-phosphatase activity
BFP66_RS04045	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BFP66_RS04045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFP66_RS04055	COG0573	inorganic phosphate transmembrane transporter activity
BFP66_RS04060	COG0581	inorganic phosphate transmembrane transporter activity
BFP66_RS04065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BFP66_RS04070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BFP66_RS04075	COG0704	Plays a role in the regulation of phosphate uptake
BFP66_RS04085	COG0745	RESPONSE REGULATOR receiver
BFP66_RS04090	COG5002	protein histidine kinase activity
BFP66_RS04105	COG0268	Binds directly to 16S ribosomal RNA
BFP66_RS04110	COG1072	(Pantothenic acid kinase))
BFP66_RS04115	COG2813	Specifically methylates the guanine in position
BFP66_RS04120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BFP66_RS04130	COG0295	cytidine deaminase activity
BFP66_RS04135	COG1744	ABC transporter substrate-binding protein PnrA-like
BFP66_RS04140	COG3845	ABC transporter
BFP66_RS04145	COG4603	Belongs to the binding-protein-dependent transport system permease family
BFP66_RS04150	COG1079	Belongs to the binding-protein-dependent transport system permease family
BFP66_RS04155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BFP66_RS04160	COG0039	L-malate dehydrogenase activity
BFP66_RS04165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BFP66_RS04170	COG3764	Sortase (surface protein transpeptidase)
BFP66_RS04180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BFP66_RS04185	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BFP66_RS04200	COG1104	cysteine desulfurase activity
BFP66_RS04210	COG4116	CYTH
BFP66_RS04215	COG2357	RelA SpoT domain protein
BFP66_RS04220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BFP66_RS04225	COG0564	pseudouridine synthase activity
BFP66_RS04230	COG0280	phosphate acetyltransferase
BFP66_RS04235	COG1132	(ABC) transporter
BFP66_RS04240	COG1132	(ABC) transporter
BFP66_RS04250	COG1194	a g-specific adenine glycosylase
BFP66_RS04255	COG1396	sequence-specific DNA binding
BFP66_RS04285	COG1349	DNA-binding transcription factor activity
BFP66_RS04290	COG0698	ribose 5-phosphate isomerase
BFP66_RS04295	COG0698	ribose 5-phosphate isomerase
BFP66_RS04300	COG1105	Belongs to the carbohydrate kinase PfkB family
BFP66_RS04305	COG3684	Belongs to the aldolase LacD family
BFP66_RS04310	COG3711	transcriptional antiterminator
BFP66_RS04320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BFP66_RS04320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BFP66_RS04345	COG2873	o-acetylhomoserine
BFP66_RS04350	COG0488	(ABC) transporter
BFP66_RS04360	COG1126	abc transporter atp-binding protein
BFP66_RS04375	COG3583	domain protein
BFP66_RS04500	COG3344	reverse transcriptase
BFP66_RS04515	COG1132	(ABC) transporter
BFP66_RS04605	COG1475	DNA binding
BFP66_RS04610	COG4443	Transcriptional Coactivator p15 (PC4)
BFP66_RS04700	COG3843	relaxase mobilization nuclease domain protein
BFP66_RS04730	COG1136	(ABC) transporter
BFP66_RS04745	COG2197	response regulator
BFP66_RS04750	COG1396	sequence-specific DNA binding
BFP66_RS04780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFP66_RS04785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFP66_RS04795	COG0297	glycogen (starch) synthase activity
BFP66_RS04800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFP66_RS04820	COG0167	dihydroorotate dehydrogenase activity
BFP66_RS04825	COG0284	orotidine-5'-phosphate decarboxylase activity
BFP66_RS04830	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BFP66_RS04840	COG0463	Glycosyl transferase, family 2
BFP66_RS04845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BFP66_RS04855	COG0737	Belongs to the 5'-nucleotidase family
BFP66_RS04870	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BFP66_RS04875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFP66_RS04885	COG1272	protein, Hemolysin III
BFP66_RS04895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFP66_RS04895	COG0425	Belongs to the sulfur carrier protein TusA family
BFP66_RS04900	COG0110	maltose O-acetyltransferase activity
BFP66_RS04905	COG0758	DNA mediated transformation
BFP66_RS04910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BFP66_RS04915	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BFP66_RS04920	COG0222	ribosome binding
BFP66_RS04925	COG0647	UMP catabolic process
BFP66_RS04930	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BFP66_RS04940	COG2382	esterase
BFP66_RS04965	COG1136	(ABC) transporter
BFP66_RS04970	COG0577	efflux transmembrane transporter activity
BFP66_RS04985	COG0745	RESPONSE REGULATOR receiver
BFP66_RS05000	COG4974	Belongs to the 'phage' integrase family
BFP66_RS05020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BFP66_RS05025	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BFP66_RS05030	COG2188	Transcriptional regulator
BFP66_RS05040	COG4268	DNA restriction-modification system
BFP66_RS05045	COG1401	restriction endodeoxyribonuclease activity
BFP66_RS05070	COG4221	oxidoreductase activity
BFP66_RS05075	COG0741	lytic transglycosylase activity
BFP66_RS05085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BFP66_RS05095	COG0009	L-threonylcarbamoyladenylate synthase
BFP66_RS05100	COG2890	protein-(glutamine-N5) methyltransferase activity
BFP66_RS05105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BFP66_RS05130	COG0481	GTPase activity
BFP66_RS05155	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BFP66_RS05165	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BFP66_RS05170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BFP66_RS05185	COG1940	carbohydrate kinase activity
BFP66_RS05200	COG0488	(ABC) transporter
BFP66_RS05205	COG0617	tRNA 3'-terminal CCA addition
BFP66_RS05210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BFP66_RS05215	COG1307	EDD domain protein, DegV family
BFP66_RS05225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFP66_RS05225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFP66_RS05225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFP66_RS05230	COG1105	Belongs to the carbohydrate kinase PfkB family
BFP66_RS05235	COG1349	DNA-binding transcription factor activity
BFP66_RS05245	COG0336	Belongs to the RNA methyltransferase TrmD family
BFP66_RS05250	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BFP66_RS05255	COG0534	Mate efflux family protein
BFP66_RS05265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BFP66_RS05270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BFP66_RS05285	COG1177	transmembrane transport
BFP66_RS05290	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFP66_RS05295	COG3842	ATPase activity
BFP66_RS05300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BFP66_RS05305	COG0083	homoserine kinase activity
BFP66_RS05310	COG0460	homoserine dehydrogenase
BFP66_RS05315	COG0726	polysaccharide deacetylase
BFP66_RS05320	COG1132	(ABC) transporter
BFP66_RS05335	COG0228	four-way junction DNA binding
BFP66_RS05345	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BFP66_RS05350	COG2136	Putative SAM-dependent methyltransferase
BFP66_RS05350	COG2521	methyltransferase
BFP66_RS05360	COG0505	Belongs to the CarA family
BFP66_RS05365	COG0540	Belongs to the ATCase OTCase family
BFP66_RS05370	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BFP66_RS05380	COG2824	Alkylphosphonate utilization operon protein PhnA
BFP66_RS05385	COG0564	pseudouridine synthase activity
BFP66_RS05405	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BFP66_RS05410	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BFP66_RS05425	COG3843	relaxase mobilization nuclease domain protein
BFP66_RS05555	COG1114	Component of the transport system for branched-chain amino acids
BFP66_RS05560	COG0301	tRNA thio-modification
BFP66_RS05565	COG1104	cysteine desulfurase activity
BFP66_RS05590	COG0539	negative regulation of cytoplasmic translation
BFP66_RS05610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFP66_RS05620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BFP66_RS05630	COG0187	DNA topoisomerase II activity
BFP66_RS05640	COG1074	ATP-dependent DNA helicase activity
BFP66_RS05645	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BFP66_RS05670	COG1131	(ABC) transporter
BFP66_RS05700	COG1011	Hydrolase
BFP66_RS05710	COG0210	DNA helicase
BFP66_RS05725	COG1164	Oligoendopeptidase f
BFP66_RS05735	COG2801	Transposase and inactivated derivatives
BFP66_RS05745	COG0346	lactoylglutathione lyase activity
BFP66_RS05750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFP66_RS05755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BFP66_RS05770	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFP66_RS05775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFP66_RS05780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFP66_RS05800	COG1882	Formate acetyltransferase
BFP66_RS05805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BFP66_RS05810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BFP66_RS05815	COG1447	Phosphotransferase system cellobiose-specific component IIA
BFP66_RS05825	COG1349	DNA-binding transcription factor activity
BFP66_RS05830	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFP66_RS05860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFP66_RS05870	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BFP66_RS05880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BFP66_RS05885	COG4684	Psort location CytoplasmicMembrane, score
BFP66_RS05890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFP66_RS05910	COG2801	Transposase and inactivated derivatives
BFP66_RS05930	COG0531	amino acid
BFP66_RS05940	COG0708	Exodeoxyribonuclease III
BFP66_RS05950	COG1393	Belongs to the ArsC family
BFP66_RS05955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BFP66_RS05960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFP66_RS05970	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BFP66_RS05980	COG4467	Involved in initiation control of chromosome replication
BFP66_RS05985	COG0470	DNA polymerase III
BFP66_RS05990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BFP66_RS05995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BFP66_RS06010	COG0517	IMP dehydrogenase activity
BFP66_RS06015	COG0658	competence protein
BFP66_RS06015	COG2333	competence protein COMEC
BFP66_RS06020	COG1596	polysaccharide export
BFP66_RS06020	COG1555	photosystem II stabilization
BFP66_RS06025	COG0204	Acyl-transferase
BFP66_RS06030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFP66_RS06035	COG1120	ATPase activity
BFP66_RS06040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BFP66_RS06045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFP66_RS06050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFP66_RS06055	COG0386	Belongs to the glutathione peroxidase family
BFP66_RS06060	COG1187	pseudouridine synthase activity
BFP66_RS06065	COG0435	Glutathione S-transferase
BFP66_RS06075	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BFP66_RS06080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFP66_RS06085	COG1696	Membrane protein involved in D-alanine export
BFP66_RS06140	COG1073	alpha beta
BFP66_RS06145	COG0363	glucosamine-6-phosphate deaminase activity
BFP66_RS06150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BFP66_RS06155	COG1438	arginine binding
BFP66_RS06160	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BFP66_RS06160	COG3583	domain protein
BFP66_RS06160	COG3064	Membrane
BFP66_RS06165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFP66_RS06170	COG1288	antiporter activity
BFP66_RS06175	COG0549	Belongs to the carbamate kinase family
BFP66_RS06180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFP66_RS06185	COG0454	-acetyltransferase
BFP66_RS06200	COG1481	regulation of sporulation
BFP66_RS06205	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BFP66_RS06210	COG1660	Displays ATPase and GTPase activities
BFP66_RS06215	COG0251	oxidation-reduction process
BFP66_RS06220	COG0534	Mate efflux family protein
BFP66_RS06230	COG0436	Aminotransferase
BFP66_RS06245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BFP66_RS06255	COG0562	UDP-galactopyranose mutase
BFP66_RS06260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFP66_RS06270	COG0077	Prephenate dehydratase
BFP66_RS06275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BFP66_RS06300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BFP66_RS06315	COG3475	LICD family
BFP66_RS06325	COG1216	Glycosyl transferase, family 2
BFP66_RS06340	COG4464	protein tyrosine phosphatase activity
BFP66_RS06350	COG3944	biosynthesis protein
BFP66_RS06355	COG1316	TRANSCRIPTIONal
BFP66_RS06360	COG3022	response to hydroperoxide
BFP66_RS06365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFP66_RS06380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BFP66_RS06385	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BFP66_RS06390	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BFP66_RS06415	COG2801	Transposase and inactivated derivatives
BFP66_RS06430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFP66_RS06435	COG1126	abc transporter atp-binding protein
BFP66_RS06440	COG0765	amino acid transport
BFP66_RS06445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BFP66_RS06455	COG2755	lipolytic protein G-D-S-L family
BFP66_RS06455	COG0657	acetylesterase activity
BFP66_RS06460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFP66_RS06470	COG0469	pyruvate kinase activity
BFP66_RS06475	COG0205	6-phosphofructokinase activity
BFP66_RS06485	COG2188	Transcriptional regulator
BFP66_RS06490	COG1131	(ABC) transporter
BFP66_RS06500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFP66_RS06540	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BFP66_RS06545	COG1982	Orn Lys Arg decarboxylase major
BFP66_RS06550	COG2151	metal-sulfur cluster biosynthetic enzyme
BFP66_RS06555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BFP66_RS06560	COG0358	DNA primase activity
BFP66_RS06565	COG1970	mechanosensitive ion channel activity
BFP66_RS06575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFP66_RS06580	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BFP66_RS06590	COG0647	UMP catabolic process
BFP66_RS06595	COG1051	belongs to the nudix hydrolase family
BFP66_RS06605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFP66_RS06615	COG0058	SHG alpha-glucan phosphorylase activity
BFP66_RS06620	COG0813	purine-nucleoside phosphorylase activity
BFP66_RS06625	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BFP66_RS06635	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BFP66_RS06640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFP66_RS06655	COG3421	Type III restriction
BFP66_RS06665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BFP66_RS06680	COG2268	Band 7 protein
BFP66_RS06685	COG1704	LemA family
BFP66_RS06695	COG1573	uracil-dna glycosylase
BFP66_RS06720	COG0488	(ABC) transporter
BFP66_RS06725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFP66_RS06740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BFP66_RS06745	COG3442	glutamine amidotransferase
BFP66_RS06750	COG2226	methyltransferase
BFP66_RS06765	COG0488	(ABC) transporter
BFP66_RS06800	COG3842	ATPase activity
BFP66_RS06820	COG1263	PTS System
BFP66_RS06820	COG2190	(PTS) system
BFP66_RS06820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFP66_RS06825	COG3711	transcriptional antiterminator
BFP66_RS06830	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BFP66_RS06835	COG3527	Alpha-acetolactate decarboxylase
BFP66_RS06845	COG0628	permease
BFP66_RS06850	COG2706	6-phosphogluconolactonase activity
BFP66_RS06860	COG1011	Hydrolase
BFP66_RS06890	COG0560	Phosphoserine phosphatase
BFP66_RS06895	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BFP66_RS06900	COG0187	DNA topoisomerase II activity
BFP66_RS06905	COG0693	protein deglycase activity
BFP66_RS06910	COG0772	Belongs to the SEDS family
BFP66_RS06930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BFP66_RS06935	COG0716	FMN binding
BFP66_RS06945	COG1605	Chorismate mutase
BFP66_RS06945	COG0287	Prephenate dehydrogenase
BFP66_RS06950	COG0038	chloride channel
BFP66_RS06960	COG0737	Belongs to the 5'-nucleotidase family
BFP66_RS06965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BFP66_RS06970	COG1466	dna polymerase III delta subunit
BFP66_RS07005	COG0683	leucine binding
BFP66_RS07020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BFP66_RS07025	COG0366	Alpha amylase catalytic
BFP66_RS07035	COG0395	ABC-type sugar transport system, permease component
BFP66_RS07040	COG1175	transmembrane transport
BFP66_RS07045	COG1653	transport
BFP66_RS07055	COG2207	Transcriptional regulator
BFP66_RS07060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BFP66_RS07065	COG0626	cystathionine gamma-synthase activity
BFP66_RS07085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BFP66_RS07090	COG2827	Endonuclease containing a URI domain
BFP66_RS07110	COG0640	Transcriptional regulator
BFP66_RS07115	COG0513	Belongs to the DEAD box helicase family
BFP66_RS07125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BFP66_RS07165	COG0494	nUDIX hydrolase
BFP66_RS07170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BFP66_RS07180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFP66_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
BFP66_RS07230	COG0577	efflux transmembrane transporter activity
BFP66_RS07235	COG1136	(ABC) transporter
BFP66_RS07240	COG2205	protein histidine kinase activity
BFP66_RS07255	COG0436	Aminotransferase
BFP66_RS07265	COG1174	glycine betaine transport
BFP66_RS07270	COG0517	IMP dehydrogenase activity
BFP66_RS07270	COG1125	glycine betaine transport
BFP66_RS07290	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BFP66_RS07295	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BFP66_RS07300	COG1482	cell wall glycoprotein biosynthetic process
BFP66_RS07320	COG4974	Belongs to the 'phage' integrase family
BFP66_RS07330	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BFP66_RS07350	COG3091	SprT-like family
BFP66_RS07355	COG2183	response to ionizing radiation
BFP66_RS07360	COG0656	L-ascorbic acid biosynthetic process
BFP66_RS07370	COG2801	Transposase and inactivated derivatives
BFP66_RS07375	COG4708	membrane
BFP66_RS07380	COG2246	polysaccharide biosynthetic process
BFP66_RS07390	COG0024	Methionine aminopeptidase
BFP66_RS07400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFP66_RS07405	COG2249	NAD(P)H dehydrogenase (quinone) activity
BFP66_RS07410	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BFP66_RS07415	COG2131	deaminase
BFP66_RS07435	COG1363	Peptidase, m42
BFP66_RS07450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BFP66_RS07455	COG1956	GAF domain-containing protein
BFP66_RS07465	COG1695	Transcriptional regulator
BFP66_RS07475	COG0673	inositol 2-dehydrogenase activity
BFP66_RS07480	COG0513	Belongs to the DEAD box helicase family
BFP66_RS07485	COG0726	polysaccharide deacetylase
BFP66_RS07500	COG0183	Belongs to the thiolase family
BFP66_RS07505	COG3425	synthase
BFP66_RS07540	COG3422	double-strand break repair
BFP66_RS07570	COG0582	viral genome integration into host DNA
BFP66_RS07575	COG0776	regulation of translation
BFP66_RS07585	COG2755	lipolytic protein G-D-S-L family
BFP66_RS07590	COG1307	EDD domain protein, DegV family
BFP66_RS07595	COG0497	DNA recombination
BFP66_RS07600	COG1438	arginine binding
BFP66_RS07605	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BFP66_RS07615	COG1722	exodeoxyribonuclease VII activity
BFP66_RS07620	COG1570	exodeoxyribonuclease VII activity
BFP66_RS07625	COG2321	neutral zinc metallopeptidase
BFP66_RS07630	COG1755	Isoprenylcysteine carboxyl methyltransferase
BFP66_RS07635	COG5002	protein histidine kinase activity
BFP66_RS07640	COG0745	RESPONSE REGULATOR receiver
BFP66_RS07665	COG1227	inorganic diphosphatase activity
BFP66_RS07675	COG1733	regulation of RNA biosynthetic process
BFP66_RS07700	COG2514	catechol 2,3-dioxygenase activity
BFP66_RS07710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFP66_RS07715	COG1253	flavin adenine dinucleotide binding
BFP66_RS07720	COG1119	ATPase activity
BFP66_RS07725	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BFP66_RS07745	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BFP66_RS07750	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BFP66_RS07755	COG0133	tryptophan synthase activity
BFP66_RS07770	COG4470	Protein conserved in bacteria
BFP66_RS07775	COG3480	Lon protease (S16) C-terminal proteolytic domain
BFP66_RS07780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BFP66_RS07785	COG0742	ribosomal rna small subunit methyltransferase
BFP66_RS07795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFP66_RS07800	COG4483	Protein conserved in bacteria
BFP66_RS07805	COG2197	response regulator
BFP66_RS07810	COG4585	Histidine kinase
BFP66_RS07815	COG0842	Transport permease protein
BFP66_RS07820	COG1131	(ABC) transporter
BFP66_RS07835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BFP66_RS07845	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BFP66_RS07845	COG2755	lipolytic protein G-D-S-L family
BFP66_RS07850	COG0671	phosphoesterase, PA-phosphatase related
BFP66_RS07855	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BFP66_RS07870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BFP66_RS07875	COG1187	pseudouridine synthase activity
BFP66_RS07880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BFP66_RS07885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BFP66_RS07890	COG0582	viral genome integration into host DNA
BFP66_RS07910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BFP66_RS07915	COG3763	UPF0154 protein
BFP66_RS07925	COG3579	cysteine-type endopeptidase activity
BFP66_RS07940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFP66_RS07945	COG1254	Belongs to the acylphosphatase family
BFP66_RS07955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFP66_RS07960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BFP66_RS07975	COG2801	Transposase and inactivated derivatives
BFP66_RS07980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFP66_RS07990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFP66_RS08005	COG1160	GTP binding
BFP66_RS08015	COG1484	DNA-dependent DNA replication
BFP66_RS08025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFP66_RS08030	COG0628	permease
BFP66_RS08035	COG0745	RESPONSE REGULATOR receiver
BFP66_RS08040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BFP66_RS08050	COG0492	ferredoxin-NADP+ reductase activity
BFP66_RS08060	COG0513	Belongs to the DEAD box helicase family
BFP66_RS08075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFP66_RS08080	COG0768	penicillin binding
BFP66_RS08090	COG0275	rRNA processing
BFP66_RS08135	COG4939	FMN-binding domain protein
BFP66_RS08140	COG0142	geranyltranstransferase activity
BFP66_RS08145	COG1252	NADH dehydrogenase
BFP66_RS08160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFP66_RS08165	COG0569	domain protein
BFP66_RS08170	COG0534	Mate efflux family protein
BFP66_RS08185	COG0751	glycine-tRNA ligase activity
BFP66_RS08215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFP66_RS08220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFP66_RS08225	COG1464	Belongs to the NlpA lipoprotein family
BFP66_RS08230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BFP66_RS08235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFP66_RS08240	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BFP66_RS08245	COG2252	PERMEase
BFP66_RS08250	COG0561	phosphatase activity
BFP66_RS08260	COG3715	PTS system
BFP66_RS08265	COG3716	PTS system mannose fructose sorbose family IID component
BFP66_RS08280	COG1983	PspC domain protein
BFP66_RS08285	COG1266	CAAX protease self-immunity
BFP66_RS08305	COG0439	Biotin carboxylase
BFP66_RS08320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFP66_RS08325	COG1028	Short-chain dehydrogenase reductase Sdr
BFP66_RS08330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BFP66_RS08335	COG2070	2-Nitropropane dioxygenase
BFP66_RS08345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BFP66_RS08355	COG1024	Enoyl-CoA hydratase
BFP66_RS08360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFP66_RS08365	COG0527	aspartate kinase activity
BFP66_RS08370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFP66_RS08375	COG0736	holo-[acyl-carrier-protein] synthase activity
BFP66_RS08380	COG0653	protein targeting
BFP66_RS08395	COG1940	carbohydrate kinase activity
BFP66_RS08400	COG1263	PTS System
BFP66_RS08400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFP66_RS08400	COG2190	(PTS) system
BFP66_RS08405	COG1621	beta-fructofuranosidase activity
BFP66_RS08410	COG1609	Transcriptional regulator
BFP66_RS08415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFP66_RS08430	COG0006	proline dipeptidase activity
BFP66_RS08450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BFP66_RS08470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BFP66_RS08475	COG0629	single-stranded DNA binding
BFP66_RS08485	COG0095	Lipoate-protein ligase
BFP66_RS08490	COG2723	6-phospho-beta-galactosidase activity
BFP66_RS08505	COG2723	6-phospho-beta-galactosidase activity
BFP66_RS08510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BFP66_RS08520	COG1447	Phosphotransferase system cellobiose-specific component IIA
BFP66_RS08525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFP66_RS08525	COG3711	transcriptional antiterminator
BFP66_RS08540	COG4095	Psort location CytoplasmicMembrane, score
BFP66_RS08545	COG2723	6-phospho-beta-galactosidase activity
BFP66_RS08550	COG0346	lactoylglutathione lyase activity
BFP66_RS08555	COG2723	6-phospho-beta-galactosidase activity
BFP66_RS08560	COG1917	Cupin 2, conserved barrel domain protein
BFP66_RS08560	COG2207	Transcriptional regulator
BFP66_RS08570	COG1263	PTS System
BFP66_RS08570	COG2190	(PTS) system
BFP66_RS08570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFP66_RS08575	COG3711	transcriptional antiterminator
BFP66_RS08590	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFP66_RS08595	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFP66_RS08595	COG0022	dehydrogenase e1 component
BFP66_RS08600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BFP66_RS08605	COG2860	membrane
BFP66_RS08620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BFP66_RS08625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BFP66_RS08635	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BFP66_RS08640	COG0195	Participates in both transcription termination and antitermination
BFP66_RS08650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BFP66_RS08660	COG4473	ABC transporter
BFP66_RS08665	COG1131	(ABC) transporter
BFP66_RS08670	COG0537	adenosine 5'-monophosphoramidase activity
BFP66_RS08680	COG1316	TRANSCRIPTIONal
BFP66_RS08690	COG0802	atpase or kinase
BFP66_RS08695	COG1461	Dihydroxyacetone kinase
BFP66_RS08710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFP66_RS08715	COG0601	transmembrane transport
BFP66_RS08720	COG4608	Belongs to the ABC transporter superfamily
BFP66_RS08735	COG1686	Belongs to the peptidase S11 family
BFP66_RS08750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFP66_RS08755	COG0719	Fe-S assembly protein
BFP66_RS08765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFP66_RS08770	COG4862	establishment of competence for transformation
BFP66_RS08775	COG1968	undecaprenyl-diphosphatase activity
BFP66_RS08780	COG0765	amino acid transport
BFP66_RS08800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFP66_RS08805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BFP66_RS08810	COG0440	acetolactate synthase activity
BFP66_RS08815	COG0028	Belongs to the TPP enzyme family
BFP66_RS08820	COG0463	Glycosyl transferase, family 2
BFP66_RS08835	COG0129	dihydroxy-acid dehydratase activity
BFP66_RS08845	COG2151	metal-sulfur cluster biosynthetic enzyme
BFP66_RS08870	COG1674	ftsk spoiiie
BFP66_RS08905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BFP66_RS08920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFP66_RS08935	COG3842	ATPase activity
BFP66_RS08945	COG2207	Transcriptional regulator
BFP66_RS08945	COG4753	response regulator
BFP66_RS08950	COG2972	Histidine kinase
BFP66_RS08960	COG1653	transport
BFP66_RS08965	COG0395	ABC-type sugar transport system, permease component
BFP66_RS08970	COG1175	transmembrane transport
BFP66_RS08985	COG0383	alpha-mannosidase activity
BFP66_RS09005	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BFP66_RS09025	COG1045	serine acetyltransferase
BFP66_RS09030	COG1185	polyribonucleotide nucleotidyltransferase activity
BFP66_RS09035	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BFP66_RS09080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFP66_RS09085	COG1187	pseudouridine synthase activity
BFP66_RS09100	COG0242	peptide deformylase activity
BFP66_RS09110	COG0066	3-isopropylmalate dehydratase activity
BFP66_RS09115	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BFP66_RS09140	COG2309	aminopeptidase activity
BFP66_RS09150	COG2176	DNA-directed DNA polymerase activity
BFP66_RS09155	COG2376	Dihydroxyacetone kinase
BFP66_RS09165	COG2376	Dihydroxyacetone kinase
BFP66_RS09170	COG1461	Dihydroxyacetone kinase
BFP66_RS09175	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BFP66_RS09180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFP66_RS09190	COG2801	Transposase and inactivated derivatives
BFP66_RS09195	COG0442	prolyl-tRNA aminoacylation
BFP66_RS09205	COG4589	Belongs to the CDS family
BFP66_RS09210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BFP66_RS09215	COG1862	Preprotein translocase
BFP66_RS09225	COG2918	glutathione biosynthetic process
BFP66_RS09225	COG1181	Belongs to the D-alanine--D-alanine ligase family
BFP66_RS09235	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BFP66_RS09240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFP66_RS09245	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BFP66_RS09250	COG0542	response to heat
BFP66_RS09255	COG4463	regulation of RNA biosynthetic process
BFP66_RS09265	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BFP66_RS09300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BFP66_RS09305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFP66_RS09310	COG0492	ferredoxin-NADP+ reductase activity
BFP66_RS09315	COG0564	pseudouridine synthase activity
BFP66_RS09415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFP66_RS09435	COG1564	THIamine pyrophosphokinase
BFP66_RS09445	COG1162	GTPase activity
BFP66_RS09480	COG4115	mRNA cleavage
BFP66_RS09505	COG0084	hydrolase, TatD family'
BFP66_RS09515	COG1847	R3H domain protein
BFP66_RS09525	COG0594	ribonuclease P activity
BFP66_RS09530	COG0165	Argininosuccinate lyase
BFP66_RS09535	COG0137	argininosuccinate synthase activity
BFP66_RS09545	COG1827	regulation of RNA biosynthetic process
BFP66_RS09560	COG2040	homocysteine
BFP66_RS09565	COG0833	amino acid
BFP66_RS09610	COG0756	dUTP diphosphatase activity
BFP66_RS09630	COG0431	NADPH-dependent FMN reductase
BFP66_RS09630	COG1053	succinate dehydrogenase
BFP66_RS09630	COG3976	FMN-binding domain protein
BFP66_RS09645	COG1132	(ABC) transporter
BFP66_RS09650	COG1132	(ABC) transporter
BFP66_RS09660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BFP66_RS09665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BFP66_RS09670	COG0705	Rhomboid family
BFP66_RS09675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BFP66_RS09680	COG1473	amidohydrolase
BFP66_RS09685	COG2171	N-acyltransferase activity
BFP66_RS09700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BFP66_RS09725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BFP66_RS09750	COG3623	hexulose-6-phosphate isomerase
BFP66_RS09775	COG1523	belongs to the glycosyl hydrolase 13 family
BFP66_RS09790	COG0463	Glycosyl transferase, family 2
BFP66_RS09805	COG1609	Transcriptional regulator
BFP66_RS09810	COG1126	abc transporter atp-binding protein
BFP66_RS09815	COG0765	amino acid transport
BFP66_RS09820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFP66_RS09830	COG2801	Transposase and inactivated derivatives
BFP66_RS09835	COG3942	CHAP domain
BFP66_RS09840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BFP66_RS09850	COG1447	Phosphotransferase system cellobiose-specific component IIA
BFP66_RS09860	COG3711	transcriptional antiterminator
BFP66_RS09860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFP66_RS09870	COG2723	6-phospho-beta-galactosidase activity
BFP66_RS09875	COG1486	melibiose metabolic process
BFP66_RS09885	COG4667	esterase of the alpha-beta hydrolase superfamily
BFP66_RS09890	COG3590	peptidase
BFP66_RS09895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFP66_RS09900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFP66_RS09900	COG1321	iron dependent repressor
BFP66_RS09905	COG1121	(ABC) transporter
BFP66_RS09920	COG0803	Belongs to the bacterial solute-binding protein 9 family
BFP66_RS09945	COG1490	D-aminoacyl-tRNA deacylase activity
BFP66_RS09955	COG0737	Belongs to the 5'-nucleotidase family
BFP66_RS09975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BFP66_RS10000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BFP66_RS10030	COG0737	Belongs to the 5'-nucleotidase family
BFP66_RS10040	COG1328	CTP reductase activity
BFP66_RS10045	COG1126	abc transporter atp-binding protein
BFP66_RS10055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFP66_RS10060	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BFP66_RS10075	COG1438	arginine binding
BFP66_RS10080	COG0018	arginyl-trna synthetase
BFP66_RS10100	COG1640	4-alpha-glucanotransferase
BFP66_RS10105	COG2182	Extracellular solute-binding protein
BFP66_RS10110	COG1175	transmembrane transport
BFP66_RS10115	COG3833	ABC-type maltose transport systems, permease component
BFP66_RS10120	COG5521	maltodextrose utilization protein MalA
BFP66_RS10125	COG1609	Transcriptional regulator
BFP66_RS10130	COG1523	belongs to the glycosyl hydrolase 13 family
BFP66_RS10135	COG1780	Probably involved in ribonucleotide reductase function
BFP66_RS10140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BFP66_RS10145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BFP66_RS10150	COG2153	protein acetylation
BFP66_RS10155	COG4989	oxidoreductase activity
BFP66_RS10160	COG1216	Glycosyl transferase, family 2
BFP66_RS10180	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BFP66_RS10190	COG0305	Participates in initiation and elongation during chromosome replication
BFP66_RS10195	COG0359	binds to the 23S rRNA
BFP66_RS10205	COG0445	tRNA wobble uridine modification
BFP66_RS10210	COG0494	nUDIX hydrolase
BFP66_RS10215	COG0494	nUDIX hydrolase
BFP66_RS10220	COG1733	regulation of RNA biosynthetic process
BFP66_RS10230	COG0482	sulfurtransferase activity
BFP66_RS10235	COG1760	l-serine dehydratase
BFP66_RS10240	COG1760	l-serine dehydratase
BFP66_RS10250	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BFP66_RS10255	COG1122	ATPase activity
BFP66_RS10260	COG1122	ATPase activity
BFP66_RS10265	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BFP66_RS10270	COG1426	Protein conserved in bacteria
BFP66_RS10275	COG0612	Peptidase, M16
BFP66_RS10280	COG0612	Peptidase, M16
BFP66_RS10290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BFP66_RS10295	COG0516	GMP reductase activity
BFP66_RS10295	COG0517	IMP dehydrogenase activity
BFP66_RS10305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BFP66_RS10310	COG0488	(ABC) transporter
BFP66_RS10340	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BFP66_RS10345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFP66_RS10350	COG1475	DNA binding
BFP66_RS10355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BFP66_RS10360	COG0592	DNA-directed DNA polymerase activity
BFP66_RS10380	COG0012	GTP binding
BFP66_RS10385	COG0193	aminoacyl-tRNA hydrolase activity
BFP66_RS10390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BFP66_RS10395	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BFP66_RS10415	COG0037	tRNA processing
BFP66_RS10425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins