locus-tag	class	description
CR542_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CR542_RS00010	COG0592	DNA-directed DNA polymerase activity
CR542_RS00030	COG0012	GTP binding
CR542_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
CR542_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CR542_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CR542_RS00065	COG0037	tRNA processing
CR542_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CR542_RS00185	COG1792	Involved in formation and maintenance of cell shape
CR542_RS00200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CR542_RS00205	COG0436	Aminotransferase
CR542_RS00210	COG1381	Involved in DNA repair and RecF pathway recombination
CR542_RS00215	COG0416	fatty acid biosynthetic process
CR542_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CR542_RS00245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CR542_RS00250	COG0138	bifunctional purine biosynthesis protein purh
CR542_RS00275	COG0151	Belongs to the GarS family
CR542_RS00280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CR542_RS00295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CR542_RS00325	COG1131	(ABC) transporter
CR542_RS00335	COG1132	(ABC) transporter
CR542_RS00340	COG2255	four-way junction helicase activity
CR542_RS00350	COG0546	phosphoglycolate phosphatase activity
CR542_RS00360	COG0285	dihydrofolate synthase activity
CR542_RS00375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CR542_RS00380	COG0632	four-way junction helicase activity
CR542_RS00385	COG0519	Catalyzes the synthesis of GMP from XMP
CR542_RS00400	COG1393	Belongs to the ArsC family
CR542_RS00405	COG4472	Bacterial protein of unknown function (DUF965)
CR542_RS00410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CR542_RS00415	COG3906	Belongs to the UPF0473 family
CR542_RS00430	COG0051	transcription antitermination factor activity, RNA binding
CR542_RS00435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CR542_RS00440	COG0088	Forms part of the polypeptide exit tunnel
CR542_RS00445	COG0089	rRNA binding
CR542_RS00450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CR542_RS00455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CR542_RS00460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CR542_RS00465	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CR542_RS00470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CR542_RS00475	COG0255	Belongs to the universal ribosomal protein uL29 family
CR542_RS00480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CR542_RS00485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CR542_RS00490	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CR542_RS00495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CR542_RS00500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CR542_RS00510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CR542_RS00520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CR542_RS00525	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CR542_RS00530	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CR542_RS00535	COG1841	ribosomal large subunit assembly
CR542_RS00545	COG0201	protein transport
CR542_RS00550	COG0563	adenylate kinase activity
CR542_RS00555	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CR542_RS00560	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CR542_RS00565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CR542_RS00575	COG0202	RNA polymerase activity
CR542_RS00685	COG0582	viral genome integration into host DNA
CR542_RS00695	COG2946	Replication initiation factor
CR542_RS00740	COG1121	(ABC) transporter
CR542_RS00745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CR542_RS00750	COG3443	Belongs to the bacterial solute-binding protein 9 family
CR542_RS00750	COG0803	Belongs to the bacterial solute-binding protein 9 family
CR542_RS00775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR542_RS00780	COG0085	RNA polymerase activity
CR542_RS00785	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CR542_RS00795	COG1619	proteins homologs of microcin C7 resistance protein MccF
CR542_RS00800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CR542_RS00805	COG1459	type II secretion system
CR542_RS00810	COG4537	Required for transformation and DNA binding
CR542_RS00840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CR542_RS00855	COG0285	dihydrofolate synthase activity
CR542_RS00860	COG1363	Peptidase, m42
CR542_RS00870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CR542_RS00880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR542_RS00905	COG0459	protein refolding
CR542_RS00915	COG0049	tRNA binding
CR542_RS00920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CR542_RS00925	COG3590	peptidase
CR542_RS00935	COG0126	phosphoglycerate kinase activity
CR542_RS00945	COG0789	Transcriptional regulator
CR542_RS00950	COG0174	glutamine synthetase
CR542_RS00965	COG1214	PFAM Peptidase M22, glycoprotease
CR542_RS00975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CR542_RS00980	COG2207	Transcriptional regulator
CR542_RS00990	COG1175	transmembrane transport
CR542_RS00995	COG0395	ABC-type sugar transport system, permease component
CR542_RS01015	COG2855	membrane
CR542_RS01025	COG1131	(ABC) transporter
CR542_RS01035	COG2081	HI0933 family
CR542_RS01040	COG2723	6-phospho-beta-galactosidase activity
CR542_RS01050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR542_RS01065	COG3959	Transketolase, thiamine diphosphate binding domain
CR542_RS01070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CR542_RS01075	COG0584	glycerophosphoryl diester phosphodiesterase
CR542_RS01080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CR542_RS01085	COG2222	sugar isomerase
CR542_RS01110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CR542_RS01120	COG3942	CHAP domain
CR542_RS01125	COG1882	Formate acetyltransferase
CR542_RS01140	COG2910	NAD(P)H-binding
CR542_RS01165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR542_RS01200	COG0363	glucosamine-6-phosphate deaminase activity
CR542_RS01205	COG2217	Heavy metal translocating P-type atpase
CR542_RS01215	COG2217	Heavy metal translocating P-type atpase
CR542_RS01220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CR542_RS01225	COG0681	Belongs to the peptidase S26 family
CR542_RS01250	COG0366	Alpha amylase catalytic
CR542_RS01255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR542_RS01255	COG1263	PTS System
CR542_RS01260	COG2188	Transcriptional regulator
CR542_RS01280	COG1193	negative regulation of DNA recombination
CR542_RS01345	COG3118	belongs to the thioredoxin family
CR542_RS01355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CR542_RS01355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CR542_RS01415	COG1115	amino acid carrier protein
CR542_RS01450	COG3842	ATPase activity
CR542_RS01460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CR542_RS01475	COG0668	transmembrane transport
CR542_RS01490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CR542_RS01495	COG0167	dihydroorotate dehydrogenase activity
CR542_RS01500	COG2843	Capsule synthesis protein
CR542_RS01505	COG0561	phosphatase activity
CR542_RS01520	COG1131	(ABC) transporter
CR542_RS01525	COG1309	transcriptional regulator
CR542_RS01565	COG1346	cytolysis
CR542_RS01570	COG2116	formate transmembrane transporter activity
CR542_RS01575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CR542_RS01580	COG0433	COG0433 Predicted ATPase
CR542_RS01585	COG0494	nUDIX hydrolase
CR542_RS01610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CR542_RS01615	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CR542_RS01620	COG0124	histidyl-tRNA synthetase
CR542_RS01625	COG1064	alcohol dehydrogenase
CR542_RS01630	COG1012	belongs to the aldehyde dehydrogenase family
CR542_RS01630	COG1454	alcohol dehydrogenase
CR542_RS01650	COG1132	(ABC) transporter
CR542_RS01660	COG0534	Mate efflux family protein
CR542_RS01665	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CR542_RS01680	COG1304	FMN binding
CR542_RS01685	COG1132	(ABC) transporter
CR542_RS01690	COG1132	(ABC) transporter
CR542_RS01695	COG3830	Belongs to the UPF0237 family
CR542_RS01700	COG2848	UPF0210 protein
CR542_RS01705	COG0588	phosphoglycerate mutase activity
CR542_RS01710	COG1420	regulation of RNA biosynthetic process
CR542_RS01715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CR542_RS01720	COG0443	Heat shock 70 kDa protein
CR542_RS01725	COG0484	heat shock protein binding
CR542_RS01735	COG0095	Lipoate-protein ligase
CR542_RS01745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR542_RS01750	COG0765	amino acid transport
CR542_RS01765	COG3655	Transcriptional regulator
CR542_RS01775	COG2217	Heavy metal translocating P-type atpase
CR542_RS01800	COG4475	Protein of unknown function (DUF436)
CR542_RS01825	COG4221	oxidoreductase activity
CR542_RS01830	COG0446	pyridine nucleotide-disulphide oxidoreductase
CR542_RS01830	COG1902	pentaerythritol trinitrate reductase activity
CR542_RS01850	COG0544	peptidyl-prolyl cis-trans isomerase activity
CR542_RS01880	COG3343	RNA polymerase activity
CR542_RS01885	COG0504	CTP synthase activity
CR542_RS01895	COG0191	fructose-bisphosphate aldolase activity
CR542_RS01900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CR542_RS01935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CR542_RS01965	COG0436	Aminotransferase
CR542_RS01970	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CR542_RS01975	COG1335	isochorismatase
CR542_RS01985	COG0335	large ribosomal subunit rRNA binding
CR542_RS01995	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CR542_RS02000	COG0154	amidase activity
CR542_RS02005	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CR542_RS02015	COG1609	Transcriptional regulator
CR542_RS02020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CR542_RS02025	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CR542_RS02040	COG3142	Participates in the control of copper homeostasis
CR542_RS02055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CR542_RS02065	COG1534	Rna-binding protein
CR542_RS02070	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CR542_RS02075	COG1713	HD superfamily hydrolase involved in NAD metabolism
CR542_RS02090	COG0799	negative regulation of ribosome biogenesis
CR542_RS02100	COG2226	methyltransferase
CR542_RS02115	COG0789	Transcriptional regulator
CR542_RS02125	COG0242	peptide deformylase activity
CR542_RS02135	COG1640	4-alpha-glucanotransferase
CR542_RS02140	COG0058	SHG alpha-glucan phosphorylase activity
CR542_RS02155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR542_RS02155	COG2190	(PTS) system
CR542_RS02155	COG1263	PTS System
CR542_RS02170	COG0217	transcriptional regulatory protein
CR542_RS02180	COG4720	Psort location CytoplasmicMembrane, score
CR542_RS02190	COG1054	Belongs to the UPF0176 family
CR542_RS02200	COG1122	ATPase activity
CR542_RS02215	COG0357	Ribosomal RNA small subunit methyltransferase G
CR542_RS02220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR542_RS02225	COG3331	DNA recombination
CR542_RS02230	COG4474	Belongs to the UPF0398 family
CR542_RS02235	COG3599	regulation of cell shape
CR542_RS02245	COG0116	Belongs to the methyltransferase superfamily
CR542_RS02255	COG1854	S-ribosylhomocysteine lyase activity
CR542_RS02260	COG1418	mRNA catabolic process
CR542_RS02270	COG1758	RNA polymerase activity
CR542_RS02280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CR542_RS02285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CR542_RS02290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CR542_RS02290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CR542_RS02295	COG0631	protein serine/threonine phosphatase activity
CR542_RS02300	COG0515	serine threonine protein kinase
CR542_RS02300	COG2815	serine threonine protein kinase
CR542_RS02325	COG1098	S1 RNA binding domain
CR542_RS02335	COG4974	Belongs to the 'phage' integrase family
CR542_RS02495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CR542_RS02500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CR542_RS02505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CR542_RS02520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CR542_RS02525	COG3022	response to hydroperoxide
CR542_RS02535	COG3944	biosynthesis protein
CR542_RS02545	COG4464	protein tyrosine phosphatase activity
CR542_RS02560	COG0438	transferase activity, transferring glycosyl groups
CR542_RS02575	COG1442	glycosyl transferase family 8
CR542_RS02575	COG1216	Glycosyl transferase, family 2
CR542_RS02580	COG1216	Glycosyl transferase, family 2
CR542_RS02580	COG1442	glycosyl transferase family 8
CR542_RS02615	COG2089	acid synthase
CR542_RS02630	COG1083	cytidylyl-transferase
CR542_RS02630	COG2755	lipolytic protein G-D-S-L family
CR542_RS02695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CR542_RS02700	COG0077	Prephenate dehydratase
CR542_RS02710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CR542_RS02720	COG0562	UDP-galactopyranose mutase
CR542_RS02725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CR542_RS02740	COG0436	Aminotransferase
CR542_RS02750	COG0017	Asparaginyl-tRNA synthetase
CR542_RS02770	COG0534	Mate efflux family protein
CR542_RS02775	COG0251	oxidation-reduction process
CR542_RS02780	COG1660	Displays ATPase and GTPase activities
CR542_RS02785	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CR542_RS02790	COG1481	regulation of sporulation
CR542_RS02805	COG0454	-acetyltransferase
CR542_RS02810	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CR542_RS02815	COG0549	Belongs to the carbamate kinase family
CR542_RS02820	COG1288	antiporter activity
CR542_RS02825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CR542_RS02830	COG3064	Membrane
CR542_RS02830	COG3583	domain protein
CR542_RS02830	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CR542_RS02835	COG1438	arginine binding
CR542_RS02840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CR542_RS02845	COG0363	glucosamine-6-phosphate deaminase activity
CR542_RS02880	COG1696	Membrane protein involved in D-alanine export
CR542_RS02885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CR542_RS02890	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CR542_RS02900	COG0435	Glutathione S-transferase
CR542_RS02905	COG1187	pseudouridine synthase activity
CR542_RS02910	COG0386	Belongs to the glutathione peroxidase family
CR542_RS02915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CR542_RS02920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CR542_RS02925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CR542_RS02930	COG1120	ATPase activity
CR542_RS02935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CR542_RS02940	COG0204	Acyl-transferase
CR542_RS02945	COG1555	photosystem II stabilization
CR542_RS02945	COG1596	polysaccharide export
CR542_RS02950	COG0658	competence protein
CR542_RS02950	COG2333	competence protein COMEC
CR542_RS02955	COG0517	IMP dehydrogenase activity
CR542_RS02970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR542_RS02975	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CR542_RS02980	COG0470	DNA polymerase III
CR542_RS02985	COG4467	Involved in initiation control of chromosome replication
CR542_RS02995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CR542_RS03005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CR542_RS03010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CR542_RS03015	COG1393	Belongs to the ArsC family
CR542_RS03030	COG0708	Exodeoxyribonuclease III
CR542_RS03040	COG0531	amino acid
CR542_RS03070	COG1061	Type III restriction enzyme res subunit
CR542_RS03100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CR542_RS03105	COG4684	Psort location CytoplasmicMembrane, score
CR542_RS03110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CR542_RS03120	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CR542_RS03160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CR542_RS03165	COG1349	DNA-binding transcription factor activity
CR542_RS03175	COG1447	Phosphotransferase system cellobiose-specific component IIA
CR542_RS03180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR542_RS03185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR542_RS03190	COG1882	Formate acetyltransferase
CR542_RS03210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CR542_RS03215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CR542_RS03235	COG1739	Uncharacterized protein family UPF0029
CR542_RS03240	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CR542_RS03320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CR542_RS03330	COG3557	Belongs to the UPF0374 family
CR542_RS03340	COG2188	Transcriptional regulator
CR542_RS03345	COG2188	Transcriptional regulator
CR542_RS03355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR542_RS03365	COG3716	PTS system mannose fructose sorbose family IID component
CR542_RS03375	COG2017	converts alpha-aldose to the beta-anomer
CR542_RS03390	COG0346	lactoylglutathione lyase activity
CR542_RS03425	COG0494	nUDIX hydrolase
CR542_RS03440	COG1217	gtp-binding protein TYPA
CR542_RS03455	COG0681	Belongs to the peptidase S26 family
CR542_RS03490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CR542_RS03505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CR542_RS03510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CR542_RS03515	COG1799	cell septum assembly
CR542_RS03530	COG3599	regulation of cell shape
CR542_RS03555	COG0494	nUDIX hydrolase
CR542_RS03555	COG0406	alpha-ribazole phosphatase activity
CR542_RS03560	COG0542	response to heat
CR542_RS03565	COG4703	Protein of unknown function (DUF1797)
CR542_RS03570	COG0765	amino acid transport
CR542_RS03580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CR542_RS03620	COG0789	Transcriptional regulator
CR542_RS03635	COG0826	peptidase U32
CR542_RS03650	COG4443	Transcriptional Coactivator p15 (PC4)
CR542_RS03655	COG1268	BioY protein
CR542_RS03665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CR542_RS03675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CR542_RS03680	COG1136	(ABC) transporter
CR542_RS03685	COG0577	efflux transmembrane transporter activity
CR542_RS03715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CR542_RS03725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CR542_RS03735	COG3859	Proton-coupled thiamine transporter YuaJ
CR542_RS03755	COG0772	Belongs to the SEDS family
CR542_RS03760	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CR542_RS03775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CR542_RS03780	COG0149	triose-phosphate isomerase activity
CR542_RS03790	COG1078	dGTPase activity
CR542_RS03825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CR542_RS03835	COG2884	Cell division ATP-binding protein ftsE
CR542_RS03840	COG2177	Part of the ABC transporter FtsEX involved in
CR542_RS03865	COG1132	(ABC) transporter
CR542_RS03870	COG1132	(ABC) transporter
CR542_RS03875	COG1011	Hydrolase
CR542_RS03895	COG1737	Transcriptional regulator
CR542_RS03905	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CR542_RS03910	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CR542_RS03915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CR542_RS03920	COG0237	dephospho-CoA kinase activity
CR542_RS03925	COG2814	Major facilitator Superfamily
CR542_RS03930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CR542_RS03940	COG0017	Asparaginyl-tRNA synthetase
CR542_RS03945	COG0557	exoribonuclease II activity
CR542_RS03950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CR542_RS03955	COG1063	alcohol dehydrogenase
CR542_RS03970	COG2217	Heavy metal translocating P-type atpase
CR542_RS03975	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CR542_RS03985	COG1136	(ABC) transporter
CR542_RS04005	COG3547	Transposase (IS116 IS110 IS902 family)
CR542_RS04025	COG0626	cystathionine gamma-synthase activity
CR542_RS04030	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CR542_RS04035	COG2207	Transcriptional regulator
CR542_RS04045	COG1653	transport
CR542_RS04050	COG1175	transmembrane transport
CR542_RS04055	COG0395	ABC-type sugar transport system, permease component
CR542_RS04065	COG0366	Alpha amylase catalytic
CR542_RS04070	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CR542_RS04085	COG0683	leucine binding
CR542_RS04120	COG1466	dna polymerase III delta subunit
CR542_RS04125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CR542_RS04130	COG0737	Belongs to the 5'-nucleotidase family
CR542_RS04140	COG0038	chloride channel
CR542_RS04145	COG0287	Prephenate dehydrogenase
CR542_RS04145	COG1605	Chorismate mutase
CR542_RS04155	COG0716	FMN binding
CR542_RS04160	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CR542_RS04180	COG1702	phosphate starvation-inducible protein PhoH
CR542_RS04185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CR542_RS04190	COG2807	transmembrane transport
CR542_RS04200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CR542_RS04205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CR542_RS04215	COG1234	tRNA 3'-trailer cleavage
CR542_RS04220	COG0300	oxidoreductase activity
CR542_RS04230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CR542_RS04235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CR542_RS04235	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CR542_RS04245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CR542_RS04265	COG2384	SAM-dependent methyltransferase
CR542_RS04270	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CR542_RS04280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CR542_RS04295	COG1088	dTDP-glucose 4,6-dehydratase activity
CR542_RS04300	COG1091	dTDP-4-dehydrorhamnose reductase activity
CR542_RS04330	COG1216	Glycosyl transferase, family 2
CR542_RS04330	COG1442	glycosyl transferase family 8
CR542_RS04360	COG1442	glycosyl transferase family 8
CR542_RS04365	COG1442	glycosyl transferase family 8
CR542_RS04365	COG1216	Glycosyl transferase, family 2
CR542_RS04380	COG1216	Glycosyl transferase, family 2
CR542_RS04410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CR542_RS04420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CR542_RS04435	COG1368	sulfuric ester hydrolase activity
CR542_RS04440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CR542_RS04445	COG0710	3-dehydroquinate dehydratase activity
CR542_RS04450	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CR542_RS04455	COG0287	Prephenate dehydrogenase
CR542_RS04460	COG3679	Belongs to the UPF0342 family
CR542_RS04585	COG1164	Oligoendopeptidase f
CR542_RS04600	COG0210	DNA helicase
CR542_RS04610	COG1011	Hydrolase
CR542_RS04640	COG1131	(ABC) transporter
CR542_RS04670	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CR542_RS04675	COG1074	ATP-dependent DNA helicase activity
CR542_RS04685	COG0187	DNA topoisomerase II activity
CR542_RS04690	COG2184	nucleotidyltransferase activity
CR542_RS04705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CR542_RS04715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CR542_RS04740	COG0539	negative regulation of cytoplasmic translation
CR542_RS04765	COG1104	cysteine desulfurase activity
CR542_RS04770	COG0301	tRNA thio-modification
CR542_RS04775	COG1114	Component of the transport system for branched-chain amino acids
CR542_RS04780	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CR542_RS04785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CR542_RS04805	COG0564	pseudouridine synthase activity
CR542_RS04810	COG2824	Alkylphosphonate utilization operon protein PhnA
CR542_RS04820	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CR542_RS04825	COG0540	Belongs to the ATCase OTCase family
CR542_RS04830	COG0505	Belongs to the CarA family
CR542_RS04840	COG2521	methyltransferase
CR542_RS04840	COG2136	Putative SAM-dependent methyltransferase
CR542_RS04845	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CR542_RS04855	COG0228	four-way junction DNA binding
CR542_RS04870	COG1132	(ABC) transporter
CR542_RS04875	COG0726	polysaccharide deacetylase
CR542_RS04885	COG0083	homoserine kinase activity
CR542_RS04895	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CR542_RS04900	COG3842	ATPase activity
CR542_RS04905	COG1176	ABC-type spermidine putrescine transport system, permease component I
CR542_RS04910	COG1177	transmembrane transport
CR542_RS04920	COG0038	chloride channel
CR542_RS04935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CR542_RS04940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CR542_RS04950	COG0534	Mate efflux family protein
CR542_RS04955	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CR542_RS04960	COG0336	Belongs to the RNA methyltransferase TrmD family
CR542_RS04965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CR542_RS04970	COG1349	DNA-binding transcription factor activity
CR542_RS04975	COG1105	Belongs to the carbohydrate kinase PfkB family
CR542_RS04980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR542_RS04980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR542_RS04980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CR542_RS04990	COG1307	EDD domain protein, DegV family
CR542_RS04995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CR542_RS05000	COG0617	tRNA 3'-terminal CCA addition
CR542_RS05005	COG0488	(ABC) transporter
CR542_RS05015	COG1940	carbohydrate kinase activity
CR542_RS05030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CR542_RS05035	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CR542_RS05045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CR542_RS05060	COG0481	GTPase activity
CR542_RS05085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CR542_RS05090	COG2890	protein-(glutamine-N5) methyltransferase activity
CR542_RS05095	COG0009	L-threonylcarbamoyladenylate synthase
CR542_RS05105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CR542_RS05115	COG0741	lytic transglycosylase activity
CR542_RS05120	COG4221	oxidoreductase activity
CR542_RS05145	COG1401	restriction endodeoxyribonuclease activity
CR542_RS05150	COG4268	DNA restriction-modification system
CR542_RS05160	COG2188	Transcriptional regulator
CR542_RS05165	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CR542_RS05170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CR542_RS05185	COG1660	Displays ATPase and GTPase activities
CR542_RS05190	COG4974	Belongs to the 'phage' integrase family
CR542_RS05205	COG0745	RESPONSE REGULATOR receiver
CR542_RS05225	COG1136	(ABC) transporter
CR542_RS05255	COG2382	esterase
CR542_RS05265	COG3708	Transcriptional regulator
CR542_RS05265	COG2207	Transcriptional regulator
CR542_RS05270	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CR542_RS05275	COG0647	UMP catabolic process
CR542_RS05315	COG0395	ABC-type sugar transport system, permease component
CR542_RS05320	COG1175	transmembrane transport
CR542_RS05340	COG1070	Carbohydrate kinase
CR542_RS05355	COG3843	relaxase mobilization nuclease domain protein
CR542_RS05375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CR542_RS05395	COG0827	DNA restriction-modification system
CR542_RS05410	COG0270	DNA (cytosine-5-)-methyltransferase activity
CR542_RS05435	COG3942	CHAP domain
CR542_RS05435	COG1705	Flagellar rod assembly protein muramidase FlgJ
CR542_RS05495	COG4974	Belongs to the 'phage' integrase family
CR542_RS05505	COG1396	sequence-specific DNA binding
CR542_RS05525	COG1447	Phosphotransferase system cellobiose-specific component IIA
CR542_RS05535	COG1105	Belongs to the carbohydrate kinase PfkB family
CR542_RS05540	COG0698	ribose 5-phosphate isomerase
CR542_RS05545	COG0698	ribose 5-phosphate isomerase
CR542_RS05550	COG1940	carbohydrate kinase activity
CR542_RS05565	COG3843	relaxase mobilization nuclease domain protein
CR542_RS05585	COG0210	DNA helicase
CR542_RS05605	COG0542	response to heat
CR542_RS05610	COG1396	sequence-specific DNA binding
CR542_RS05665	COG4443	Transcriptional Coactivator p15 (PC4)
CR542_RS05670	COG1475	DNA binding
CR542_RS05875	COG0222	ribosome binding
CR542_RS05880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CR542_RS05885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CR542_RS05890	COG0758	DNA mediated transformation
CR542_RS05895	COG0110	maltose O-acetyltransferase activity
CR542_RS05900	COG1937	Protein conserved in bacteria
CR542_RS05910	COG0446	pyridine nucleotide-disulphide oxidoreductase
CR542_RS05920	COG1272	protein, Hemolysin III
CR542_RS05930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CR542_RS05935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CR542_RS05945	COG0424	maF-like protein
CR542_RS05950	COG0737	Belongs to the 5'-nucleotidase family
CR542_RS05960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CR542_RS05965	COG0463	Glycosyl transferase, family 2
CR542_RS05975	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CR542_RS05980	COG0284	orotidine-5'-phosphate decarboxylase activity
CR542_RS05985	COG0167	dihydroorotate dehydrogenase activity
CR542_RS05995	COG0583	DNA-binding transcription factor activity
CR542_RS06010	COG0297	glycogen (starch) synthase activity
CR542_RS06020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR542_RS06025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR542_RS06070	COG1126	abc transporter atp-binding protein
CR542_RS06080	COG0488	(ABC) transporter
CR542_RS06085	COG2873	o-acetylhomoserine
CR542_RS06110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR542_RS06110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR542_RS06120	COG3711	transcriptional antiterminator
CR542_RS06125	COG3684	Belongs to the aldolase LacD family
CR542_RS06130	COG1105	Belongs to the carbohydrate kinase PfkB family
CR542_RS06135	COG0698	ribose 5-phosphate isomerase
CR542_RS06140	COG0698	ribose 5-phosphate isomerase
CR542_RS06150	COG1349	DNA-binding transcription factor activity
CR542_RS06180	COG1396	sequence-specific DNA binding
CR542_RS06185	COG1194	a g-specific adenine glycosylase
CR542_RS06195	COG1132	(ABC) transporter
CR542_RS06200	COG1132	(ABC) transporter
CR542_RS06205	COG0280	phosphate acetyltransferase
CR542_RS06210	COG0564	pseudouridine synthase activity
CR542_RS06215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CR542_RS06220	COG2357	RelA SpoT domain protein
CR542_RS06225	COG4116	CYTH
CR542_RS06235	COG1104	cysteine desulfurase activity
CR542_RS06250	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CR542_RS06255	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CR542_RS06265	COG3764	Sortase (surface protein transpeptidase)
CR542_RS06270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CR542_RS06275	COG0039	L-malate dehydrogenase activity
CR542_RS06280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CR542_RS06290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CR542_RS06295	COG1079	Belongs to the binding-protein-dependent transport system permease family
CR542_RS06300	COG4603	Belongs to the binding-protein-dependent transport system permease family
CR542_RS06305	COG3845	ABC transporter
CR542_RS06310	COG1744	ABC transporter substrate-binding protein PnrA-like
CR542_RS06325	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CR542_RS06330	COG2813	Specifically methylates the guanine in position
CR542_RS06335	COG1072	(Pantothenic acid kinase))
CR542_RS06355	COG5002	protein histidine kinase activity
CR542_RS06360	COG0745	RESPONSE REGULATOR receiver
CR542_RS06375	COG0704	Plays a role in the regulation of phosphate uptake
CR542_RS06380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CR542_RS06385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CR542_RS06390	COG0581	inorganic phosphate transmembrane transporter activity
CR542_RS06395	COG0573	inorganic phosphate transmembrane transporter activity
CR542_RS06405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CR542_RS06405	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CR542_RS06410	COG0483	inositol monophosphate 1-phosphatase activity
CR542_RS06415	COG4476	Belongs to the UPF0223 family
CR542_RS06420	COG1393	Belongs to the ArsC family
CR542_RS06425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CR542_RS06430	COG0196	riboflavin kinase activity
CR542_RS06435	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CR542_RS06475	COG0561	phosphatase activity
CR542_RS06480	COG2195	Cleaves the N-terminal amino acid of tripeptides
CR542_RS06495	COG1695	Transcriptional regulator
CR542_RS06510	COG3759	membrane
CR542_RS06515	COG1846	Transcriptional regulator
CR542_RS06530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CR542_RS06535	COG2610	gluconate transmembrane transporter activity
CR542_RS06555	COG0302	gtp cyclohydrolase
CR542_RS06560	COG1051	belongs to the nudix hydrolase family
CR542_RS06585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR542_RS06585	COG0072	phenylalanine-tRNA ligase activity
CR542_RS06615	COG1028	Short-chain dehydrogenase reductase Sdr
CR542_RS06620	COG1312	Catalyzes the dehydration of D-mannonate
CR542_RS06630	COG0800	Aldolase
CR542_RS06640	COG3250	beta-galactosidase activity
CR542_RS06650	COG2211	Major facilitator Superfamily
CR542_RS06665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CR542_RS06675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CR542_RS06680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CR542_RS06685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CR542_RS06690	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CR542_RS06695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CR542_RS06700	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CR542_RS06705	COG0356	it plays a direct role in the translocation of protons across the membrane
CR542_RS06715	COG1597	lipid kinase activity
CR542_RS06725	COG0701	Predicted permease
CR542_RS06730	COG3689	TIGRFAM TIGR03943 family protein
CR542_RS06735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CR542_RS06750	COG0552	protein localization to endoplasmic reticulum
CR542_RS06755	COG0561	phosphatase activity
CR542_RS06760	COG0561	phosphatase activity
CR542_RS06765	COG1196	nuclear chromosome segregation
CR542_RS06810	COG0538	isocitrate dehydrogenase activity
CR542_RS06815	COG0372	Belongs to the citrate synthase family
CR542_RS06820	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CR542_RS06825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CR542_RS06830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR542_RS06835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR542_RS06840	COG1609	Transcriptional regulator
CR542_RS06855	COG5492	domain, Protein
CR542_RS06865	COG3716	PTS system mannose fructose sorbose family IID component
CR542_RS06875	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR542_RS06880	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CR542_RS06905	COG1028	Short-chain dehydrogenase reductase Sdr
CR542_RS06940	COG1476	TRANSCRIPTIONal
CR542_RS06960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CR542_RS06970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CR542_RS06975	COG4122	O-methyltransferase activity
CR542_RS07000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR542_RS07000	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR542_RS07015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CR542_RS07020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CR542_RS07025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CR542_RS07030	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CR542_RS07040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CR542_RS07040	COG1116	anion transmembrane transporter activity
CR542_RS07045	COG4120	Belongs to the binding-protein-dependent transport system permease family
CR542_RS07065	COG3684	Belongs to the aldolase LacD family
CR542_RS07080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR542_RS07085	COG1126	abc transporter atp-binding protein
CR542_RS07090	COG0765	amino acid transport
CR542_RS07095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CR542_RS07110	COG2755	lipolytic protein G-D-S-L family
CR542_RS07110	COG0657	acetylesterase activity
CR542_RS07115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CR542_RS07135	COG0469	pyruvate kinase activity
CR542_RS07140	COG0205	6-phosphofructokinase activity
CR542_RS07150	COG2188	Transcriptional regulator
CR542_RS07155	COG1131	(ABC) transporter
CR542_RS07165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CR542_RS07200	COG2151	metal-sulfur cluster biosynthetic enzyme
CR542_RS07205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CR542_RS07210	COG0358	DNA primase activity
CR542_RS07215	COG1970	mechanosensitive ion channel activity
CR542_RS07225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CR542_RS07230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CR542_RS07240	COG0647	UMP catabolic process
CR542_RS07245	COG1051	belongs to the nudix hydrolase family
CR542_RS07255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CR542_RS07265	COG0058	SHG alpha-glucan phosphorylase activity
CR542_RS07270	COG0813	purine-nucleoside phosphorylase activity
CR542_RS07275	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CR542_RS07285	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CR542_RS07290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CR542_RS07305	COG1518	maintenance of DNA repeat elements
CR542_RS07325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CR542_RS07340	COG2268	Band 7 protein
CR542_RS07345	COG1704	LemA family
CR542_RS07355	COG1573	uracil-dna glycosylase
CR542_RS07395	COG0488	(ABC) transporter
CR542_RS07400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CR542_RS07415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CR542_RS07420	COG3442	glutamine amidotransferase
CR542_RS07425	COG2226	methyltransferase
CR542_RS07435	COG0488	(ABC) transporter
CR542_RS07470	COG3842	ATPase activity
CR542_RS07490	COG2190	(PTS) system
CR542_RS07490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR542_RS07490	COG1263	PTS System
CR542_RS07495	COG3711	transcriptional antiterminator
CR542_RS07500	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CR542_RS07505	COG3527	Alpha-acetolactate decarboxylase
CR542_RS07515	COG0628	permease
CR542_RS07520	COG2706	6-phosphogluconolactonase activity
CR542_RS07530	COG1011	Hydrolase
CR542_RS07650	COG0560	Phosphoserine phosphatase
CR542_RS07655	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CR542_RS07660	COG0187	DNA topoisomerase II activity
CR542_RS07665	COG0693	protein deglycase activity
CR542_RS07670	COG0772	Belongs to the SEDS family
CR542_RS07680	COG4479	Belongs to the UPF0346 family
CR542_RS07695	COG2996	Protein conserved in bacteria
CR542_RS07700	COG0233	cytoplasmic translational termination
CR542_RS07705	COG0528	UMP kinase activity
CR542_RS07710	COG2244	polysaccharide biosynthetic process
CR542_RS07720	COG0625	glutathione transferase activity
CR542_RS07745	COG0346	lactoylglutathione lyase activity
CR542_RS07750	COG0697	spore germination
CR542_RS07750	COG1674	ftsk spoiiie
CR542_RS07755	COG1621	beta-fructofuranosidase activity
CR542_RS07770	COG0395	ABC-type sugar transport system, permease component
CR542_RS07775	COG4209	transmembrane transport
CR542_RS07780	COG1609	Transcriptional regulator
CR542_RS07800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CR542_RS07815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CR542_RS07825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CR542_RS07850	COG1181	Belongs to the D-alanine--D-alanine ligase family
CR542_RS07855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CR542_RS07860	COG0768	penicillin binding
CR542_RS07865	COG0488	(ABC) transporter
CR542_RS07880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CR542_RS07890	COG0745	RESPONSE REGULATOR receiver
CR542_RS07900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR542_RS07905	COG0765	amino acid transport
CR542_RS07910	COG0765	amino acid transport
CR542_RS07915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CR542_RS07930	COG0438	transferase activity, transferring glycosyl groups
CR542_RS07945	COG1609	Transcriptional regulator
CR542_RS07960	COG0343	queuine tRNA-ribosyltransferase activity
CR542_RS07970	COG1832	CoA-binding protein
CR542_RS07980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR542_RS07980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR542_RS07990	COG3547	Transposase (IS116 IS110 IS902 family)
CR542_RS08000	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CR542_RS08005	COG2827	Endonuclease containing a URI domain
CR542_RS08025	COG0640	Transcriptional regulator
CR542_RS08030	COG0513	Belongs to the DEAD box helicase family
CR542_RS08040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR542_RS08085	COG0494	nUDIX hydrolase
CR542_RS08090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CR542_RS08100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CR542_RS08105	COG1028	Short-chain dehydrogenase reductase Sdr
CR542_RS08130	COG0577	efflux transmembrane transporter activity
CR542_RS08135	COG1136	(ABC) transporter
CR542_RS08155	COG0436	Aminotransferase
CR542_RS08165	COG1174	glycine betaine transport
CR542_RS08170	COG1125	glycine betaine transport
CR542_RS08170	COG0517	IMP dehydrogenase activity
CR542_RS08190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CR542_RS08195	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CR542_RS08200	COG1482	cell wall glycoprotein biosynthetic process
CR542_RS08215	COG3091	SprT-like family
CR542_RS08220	COG2183	response to ionizing radiation
CR542_RS08240	COG0656	L-ascorbic acid biosynthetic process
CR542_RS08245	COG4708	membrane
CR542_RS08250	COG2246	polysaccharide biosynthetic process
CR542_RS08260	COG0024	Methionine aminopeptidase
CR542_RS08270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CR542_RS08275	COG2249	NAD(P)H dehydrogenase (quinone) activity
CR542_RS08280	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CR542_RS08290	COG2131	deaminase
CR542_RS08310	COG1363	Peptidase, m42
CR542_RS08325	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CR542_RS08330	COG1956	GAF domain-containing protein
CR542_RS08350	COG0673	inositol 2-dehydrogenase activity
CR542_RS08355	COG0513	Belongs to the DEAD box helicase family
CR542_RS08360	COG0726	polysaccharide deacetylase
CR542_RS08375	COG0183	Belongs to the thiolase family
CR542_RS08380	COG3425	synthase
CR542_RS08405	COG0776	regulation of translation
CR542_RS08415	COG2755	lipolytic protein G-D-S-L family
CR542_RS08420	COG1307	EDD domain protein, DegV family
CR542_RS08425	COG0497	DNA recombination
CR542_RS08430	COG1438	arginine binding
CR542_RS08435	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CR542_RS08445	COG1722	exodeoxyribonuclease VII activity
CR542_RS08450	COG1570	exodeoxyribonuclease VII activity
CR542_RS08455	COG2321	neutral zinc metallopeptidase
CR542_RS08460	COG1755	Isoprenylcysteine carboxyl methyltransferase
CR542_RS08465	COG5002	protein histidine kinase activity
CR542_RS08470	COG0745	RESPONSE REGULATOR receiver
CR542_RS08495	COG1227	inorganic diphosphatase activity
CR542_RS08505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CR542_RS08510	COG1253	flavin adenine dinucleotide binding
CR542_RS08515	COG1119	ATPase activity
CR542_RS08520	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CR542_RS08530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CR542_RS08535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CR542_RS08550	COG4470	Protein conserved in bacteria
CR542_RS08555	COG3480	Lon protease (S16) C-terminal proteolytic domain
CR542_RS08560	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CR542_RS08565	COG0742	ribosomal rna small subunit methyltransferase
CR542_RS08575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CR542_RS08580	COG4483	Protein conserved in bacteria
CR542_RS08585	COG2197	response regulator
CR542_RS08590	COG4585	Histidine kinase
CR542_RS08590	COG2203	Gaf domain
CR542_RS08595	COG0842	Transport permease protein
CR542_RS08600	COG1131	(ABC) transporter
CR542_RS08620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CR542_RS08630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CR542_RS08630	COG2755	lipolytic protein G-D-S-L family
CR542_RS08635	COG0671	phosphoesterase, PA-phosphatase related
CR542_RS08640	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CR542_RS08655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CR542_RS08660	COG1187	pseudouridine synthase activity
CR542_RS08665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CR542_RS08670	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CR542_RS08675	COG0582	viral genome integration into host DNA
CR542_RS08695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CR542_RS08700	COG3763	UPF0154 protein
CR542_RS08710	COG3579	cysteine-type endopeptidase activity
CR542_RS08725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CR542_RS08730	COG1254	Belongs to the acylphosphatase family
CR542_RS08735	COG0706	membrane insertase activity
CR542_RS08740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CR542_RS08745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CR542_RS08755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CR542_RS08765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CR542_RS08780	COG1160	GTP binding
CR542_RS08790	COG1484	DNA-dependent DNA replication
CR542_RS08800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CR542_RS08805	COG0628	permease
CR542_RS08810	COG0745	RESPONSE REGULATOR receiver
CR542_RS08815	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CR542_RS08825	COG0492	ferredoxin-NADP+ reductase activity
CR542_RS08835	COG0513	Belongs to the DEAD box helicase family
CR542_RS08855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CR542_RS08860	COG0768	penicillin binding
CR542_RS08870	COG0275	rRNA processing
CR542_RS08925	COG4939	FMN-binding domain protein
CR542_RS08930	COG0142	geranyltranstransferase activity
CR542_RS08935	COG1252	NADH dehydrogenase
CR542_RS08950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CR542_RS08955	COG0569	domain protein
CR542_RS08960	COG0534	Mate efflux family protein
CR542_RS08970	COG4224	UPF0291 protein
CR542_RS08975	COG0751	glycine-tRNA ligase activity
CR542_RS09000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CR542_RS09005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CR542_RS09010	COG1464	Belongs to the NlpA lipoprotein family
CR542_RS09015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CR542_RS09020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CR542_RS09025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CR542_RS09035	COG0561	phosphatase activity
CR542_RS09045	COG3715	PTS system
CR542_RS09050	COG3716	PTS system mannose fructose sorbose family IID component
CR542_RS09075	COG3177	Filamentation induced by cAMP protein fic
CR542_RS09085	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CR542_RS09370	COG0825	malonyl-CoA metabolic process
CR542_RS09380	COG0439	Biotin carboxylase
CR542_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
CR542_RS09415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CR542_RS09420	COG2070	2-Nitropropane dioxygenase
CR542_RS09430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CR542_RS09440	COG1024	Enoyl-CoA hydratase
CR542_RS09445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CR542_RS09450	COG0527	aspartate kinase activity
CR542_RS09465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CR542_RS09470	COG0736	holo-[acyl-carrier-protein] synthase activity
CR542_RS09475	COG0653	protein targeting
CR542_RS09485	COG1940	carbohydrate kinase activity
CR542_RS09490	COG2190	(PTS) system
CR542_RS09490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR542_RS09490	COG1263	PTS System
CR542_RS09495	COG1621	beta-fructofuranosidase activity
CR542_RS09500	COG1609	Transcriptional regulator
CR542_RS09505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CR542_RS09520	COG0006	proline dipeptidase activity
CR542_RS09525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CR542_RS09540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CR542_RS09545	COG0629	single-stranded DNA binding
CR542_RS09555	COG0095	Lipoate-protein ligase
CR542_RS09560	COG2723	6-phospho-beta-galactosidase activity
CR542_RS09575	COG2723	6-phospho-beta-galactosidase activity
CR542_RS09580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR542_RS09590	COG1447	Phosphotransferase system cellobiose-specific component IIA
CR542_RS09610	COG4095	Psort location CytoplasmicMembrane, score
CR542_RS09615	COG2723	6-phospho-beta-galactosidase activity
CR542_RS09620	COG0346	lactoylglutathione lyase activity
CR542_RS09625	COG2723	6-phospho-beta-galactosidase activity
CR542_RS09630	COG1917	Cupin 2, conserved barrel domain protein
CR542_RS09630	COG2207	Transcriptional regulator
CR542_RS09640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR542_RS09640	COG1263	PTS System
CR542_RS09640	COG2190	(PTS) system
CR542_RS09645	COG3711	transcriptional antiterminator
CR542_RS09660	COG0508	dehydrogenase complex catalyzes the overall conversion of
CR542_RS09665	COG0022	dehydrogenase e1 component
CR542_RS09665	COG0508	dehydrogenase complex catalyzes the overall conversion of
CR542_RS09670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CR542_RS09675	COG2860	membrane
CR542_RS09690	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CR542_RS09695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CR542_RS09705	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CR542_RS09710	COG0195	Participates in both transcription termination and antitermination
CR542_RS09720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CR542_RS09730	COG4473	ABC transporter
CR542_RS09735	COG1131	(ABC) transporter
CR542_RS09740	COG0537	adenosine 5'-monophosphoramidase activity
CR542_RS09750	COG1316	TRANSCRIPTIONal
CR542_RS09760	COG0802	atpase or kinase
CR542_RS09780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CR542_RS09785	COG0601	transmembrane transport
CR542_RS09790	COG4608	Belongs to the ABC transporter superfamily
CR542_RS09800	COG0747	negative chemotaxis
CR542_RS09805	COG1686	Belongs to the peptidase S11 family
CR542_RS09820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CR542_RS09825	COG0719	Fe-S assembly protein
CR542_RS09835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CR542_RS09840	COG4862	establishment of competence for transformation
CR542_RS09845	COG1968	undecaprenyl-diphosphatase activity
CR542_RS09850	COG0765	amino acid transport
CR542_RS09855	COG1126	abc transporter atp-binding protein
CR542_RS09870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CR542_RS09875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CR542_RS09880	COG0440	acetolactate synthase activity
CR542_RS09885	COG0028	Belongs to the TPP enzyme family
CR542_RS09905	COG0129	dihydroxy-acid dehydratase activity
CR542_RS09980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CR542_RS10000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CR542_RS10015	COG3842	ATPase activity
CR542_RS10025	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CR542_RS10045	COG1045	serine acetyltransferase
CR542_RS10050	COG1185	polyribonucleotide nucleotidyltransferase activity
CR542_RS10060	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CR542_RS10065	COG1131	(ABC) transporter
CR542_RS10110	COG1187	pseudouridine synthase activity
CR542_RS10130	COG0242	peptide deformylase activity
CR542_RS10140	COG0066	3-isopropylmalate dehydratase activity
CR542_RS10160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR542_RS10170	COG2188	Transcriptional regulator
CR542_RS10175	COG1447	Phosphotransferase system cellobiose-specific component IIA
CR542_RS10190	COG2309	aminopeptidase activity
CR542_RS10210	COG2176	DNA-directed DNA polymerase activity
CR542_RS10215	COG2376	Dihydroxyacetone kinase
CR542_RS10225	COG2376	Dihydroxyacetone kinase
CR542_RS10230	COG1461	Dihydroxyacetone kinase
CR542_RS10235	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CR542_RS10240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CR542_RS10245	COG0442	prolyl-tRNA aminoacylation
CR542_RS10255	COG4589	Belongs to the CDS family
CR542_RS10260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CR542_RS10265	COG1862	Preprotein translocase
CR542_RS10275	COG2918	glutathione biosynthetic process
CR542_RS10275	COG1181	Belongs to the D-alanine--D-alanine ligase family
CR542_RS10285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CR542_RS10290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CR542_RS10295	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CR542_RS10300	COG0542	response to heat
CR542_RS10305	COG4463	regulation of RNA biosynthetic process
CR542_RS10315	COG4932	domain protein
CR542_RS10315	COG1388	LysM domain
CR542_RS10325	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CR542_RS10335	COG0582	viral genome integration into host DNA
CR542_RS10415	COG0612	Peptidase, M16
CR542_RS10420	COG0612	Peptidase, M16
CR542_RS10425	COG1426	Protein conserved in bacteria
CR542_RS10430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CR542_RS10435	COG1122	ATPase activity
CR542_RS10440	COG1122	ATPase activity
CR542_RS10445	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CR542_RS10455	COG1760	l-serine dehydratase
CR542_RS10460	COG1760	l-serine dehydratase
CR542_RS10465	COG0482	sulfurtransferase activity
CR542_RS10475	COG1733	regulation of RNA biosynthetic process
CR542_RS10480	COG0494	nUDIX hydrolase
CR542_RS10485	COG0445	tRNA wobble uridine modification
CR542_RS10495	COG0359	binds to the 23S rRNA
CR542_RS10500	COG0305	Participates in initiation and elongation during chromosome replication
CR542_RS10510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CR542_RS10530	COG1216	Glycosyl transferase, family 2
CR542_RS10535	COG4989	oxidoreductase activity
CR542_RS10540	COG2153	protein acetylation
CR542_RS10545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CR542_RS10550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR542_RS10555	COG1780	Probably involved in ribonucleotide reductase function
CR542_RS10560	COG1523	belongs to the glycosyl hydrolase 13 family
CR542_RS10565	COG1609	Transcriptional regulator
CR542_RS10570	COG5521	maltodextrose utilization protein MalA
CR542_RS10575	COG3833	ABC-type maltose transport systems, permease component
CR542_RS10580	COG1175	transmembrane transport
CR542_RS10585	COG2182	Extracellular solute-binding protein
CR542_RS10590	COG1640	4-alpha-glucanotransferase
CR542_RS10610	COG0018	arginyl-trna synthetase
CR542_RS10615	COG1438	arginine binding
CR542_RS10635	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CR542_RS10640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR542_RS10650	COG1126	abc transporter atp-binding protein
CR542_RS10655	COG1328	CTP reductase activity
CR542_RS10665	COG0737	Belongs to the 5'-nucleotidase family
CR542_RS10695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CR542_RS10715	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CR542_RS10740	COG0737	Belongs to the 5'-nucleotidase family
CR542_RS10750	COG1490	D-aminoacyl-tRNA deacylase activity
CR542_RS10770	COG0803	Belongs to the bacterial solute-binding protein 9 family
CR542_RS10785	COG1121	(ABC) transporter
CR542_RS10790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CR542_RS10790	COG1321	iron dependent repressor
CR542_RS10795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CR542_RS10800	COG3590	peptidase
CR542_RS10810	COG1486	melibiose metabolic process
CR542_RS10815	COG2723	6-phospho-beta-galactosidase activity
CR542_RS10825	COG3711	transcriptional antiterminator
CR542_RS10825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CR542_RS10835	COG1447	Phosphotransferase system cellobiose-specific component IIA
CR542_RS10845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR542_RS10850	COG3942	CHAP domain
CR542_RS10855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR542_RS10860	COG0765	amino acid transport
CR542_RS10865	COG1126	abc transporter atp-binding protein
CR542_RS10870	COG1609	Transcriptional regulator
CR542_RS10875	COG1523	belongs to the glycosyl hydrolase 13 family
CR542_RS10900	COG3623	hexulose-6-phosphate isomerase
CR542_RS10925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CR542_RS10950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CR542_RS10960	COG2171	N-acyltransferase activity
CR542_RS10965	COG1473	amidohydrolase
CR542_RS10970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CR542_RS10975	COG0705	Rhomboid family
CR542_RS10980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CR542_RS10985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CR542_RS10995	COG1132	(ABC) transporter
CR542_RS11000	COG1132	(ABC) transporter
CR542_RS11075	COG0582	viral genome integration into host DNA
CR542_RS11080	COG0756	dUTP diphosphatase activity
CR542_RS11135	COG1827	regulation of RNA biosynthetic process
CR542_RS11145	COG0137	argininosuccinate synthase activity
CR542_RS11150	COG0165	Argininosuccinate lyase
CR542_RS11155	COG0594	ribonuclease P activity
CR542_RS11165	COG1847	R3H domain protein
CR542_RS11175	COG0084	hydrolase, TatD family'
CR542_RS11200	COG4115	mRNA cleavage
CR542_RS11225	COG1132	(ABC) transporter
CR542_RS11235	COG1162	GTPase activity
CR542_RS11245	COG1564	THIamine pyrophosphokinase
CR542_RS11265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CR542_RS11405	COG0564	pseudouridine synthase activity
CR542_RS11410	COG0492	ferredoxin-NADP+ reductase activity
CR542_RS11415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR542_RS11420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CR542_RS11455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CR542_RS11465	COG0517	IMP dehydrogenase activity
CR542_RS11465	COG0516	GMP reductase activity
CR542_RS11475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR542_RS11480	COG0488	(ABC) transporter
CR542_RS11510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CR542_RS11515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CR542_RS11520	COG1475	DNA binding