CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 Gene3D G3DSA:3.50.50.60 136 258 3.8E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 SUPERFAMILY SSF51905 1 301 1.02E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.1E-34 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 137 5.1E-34 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 5.1E-34 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 5.1E-34 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 5.1E-34 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 388 403 2.2E-52 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 323 344 2.2E-52 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.2E-52 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 122 131 2.2E-52 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 2.2E-52 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 184 2.2E-52 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 2.2E-52 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 2.2E-52 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 430 2.2E-52 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 Gene3D G3DSA:3.50.50.60 1 135 5.8E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 433 5.4E-27 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 Gene3D G3DSA:3.50.50.60 259 315 6.5E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 301 2.3E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 SUPERFAMILY SSF55424 326 435 1.25E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 Gene3D G3DSA:3.30.390.30 326 437 1.7E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 PIRSF PIRSF000350 1 436 1.8E-78 T 28-03-2018 CWM22_RS07560 9c5032388c38f06a6b7b355782731a1e 438 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 83 138 3.0E-5 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 Pfam PF02863 Arginine repressor, C-terminal domain 80 142 2.8E-16 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 Hamap MF_00173 Arginine repressor [argR]. 1 146 46.322 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 SUPERFAMILY SSF46785 1 68 5.03E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS13060 adbae379913460136b91e53573a1835a 146 Pfam PF01316 Arginine repressor, DNA binding domain 1 67 2.1E-21 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 PRINTS PR01467 Bacterial arginine repressor signature 114 129 5.8E-15 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 PRINTS PR01467 Bacterial arginine repressor signature 84 97 5.8E-15 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 PRINTS PR01467 Bacterial arginine repressor signature 21 34 5.8E-15 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 PRINTS PR01467 Bacterial arginine repressor signature 37 52 5.8E-15 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 SUPERFAMILY SSF55252 76 144 3.53E-16 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 143 2.4E-43 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 Gene3D G3DSA:3.30.1360.40 71 142 1.9E-18 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWM22_RS13060 adbae379913460136b91e53573a1835a 146 Gene3D G3DSA:1.10.10.10 3 64 3.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06915 305df3bcb363b450eeec5dbc4f714917 137 SUPERFAMILY SSF54919 1 136 3.14E-54 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS06915 305df3bcb363b450eeec5dbc4f714917 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 137 30.077 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS06915 305df3bcb363b450eeec5dbc4f714917 137 Pfam PF00334 Nucleoside diphosphate kinase 2 135 4.2E-51 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS06915 305df3bcb363b450eeec5dbc4f714917 137 SMART SM00562 1 136 9.6E-65 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS06915 305df3bcb363b450eeec5dbc4f714917 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 7.2E-33 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS06915 305df3bcb363b450eeec5dbc4f714917 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 7.2E-33 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS06915 305df3bcb363b450eeec5dbc4f714917 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 116 135 7.2E-33 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS06915 305df3bcb363b450eeec5dbc4f714917 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 7.2E-33 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS06915 305df3bcb363b450eeec5dbc4f714917 137 Gene3D G3DSA:3.30.70.141 1 137 5.9E-52 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS06490 7cbba543531959f6d6e513605f89f1a8 245 SMART SM00650 17 179 3.9E-60 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CWM22_RS06490 7cbba543531959f6d6e513605f89f1a8 245 Gene3D G3DSA:1.10.8.100 184 242 3.8E-31 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CWM22_RS06490 7cbba543531959f6d6e513605f89f1a8 245 Gene3D G3DSA:3.40.50.150 1 183 1.8E-36 T 28-03-2018 CWM22_RS06490 7cbba543531959f6d6e513605f89f1a8 245 SUPERFAMILY SSF53335 1 238 3.88E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06490 7cbba543531959f6d6e513605f89f1a8 245 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 60 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CWM22_RS06490 7cbba543531959f6d6e513605f89f1a8 245 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 239 3.9E-76 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CWM22_RS10130 72119145abd424a97d1908ea944057ab 136 SMART SM00422 1 70 1.1E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS10130 72119145abd424a97d1908ea944057ab 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.3E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS10130 72119145abd424a97d1908ea944057ab 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.3E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS10130 72119145abd424a97d1908ea944057ab 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.3E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS10130 72119145abd424a97d1908ea944057ab 136 Pfam PF13411 MerR HTH family regulatory protein 1 67 8.7E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS10130 72119145abd424a97d1908ea944057ab 136 Gene3D G3DSA:1.10.1660.10 56 131 7.1E-15 T 28-03-2018 CWM22_RS10130 72119145abd424a97d1908ea944057ab 136 Gene3D G3DSA:1.10.1660.10 1 55 2.4E-17 T 28-03-2018 CWM22_RS10130 72119145abd424a97d1908ea944057ab 136 SUPERFAMILY SSF46955 1 114 3.66E-30 T 28-03-2018 IPR009061 Putative DNA-binding domain CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.5.420 578 635 2.4E-11 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:3.90.182.10 3779 3962 1.1E-12 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:3.90.1810.10 5099 5196 0.0017 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:3.90.1810.10 4886 4970 0.032 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 4192 4220 0.052 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 3334 3364 4.3E-4 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 4380 4430 0.037 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 2348 2371 0.2 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 2229 2286 0.0055 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 1619 1659 0.1 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 3582 3631 0.0073 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 4507 4535 0.075 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 2683 2728 0.0075 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 5348 5368 0.23 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 5589 5610 0.42 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 3741 3808 1.9E-4 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 3397 3449 8.1E-5 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 4303 4325 0.12 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 4088 4115 0.049 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 3226 3274 0.27 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 3667 3717 0.015 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 2851 2905 0.2 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 3138 3178 5.2E-4 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 4716 4749 0.34 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 3879 3905 0.59 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 2503 2553 1.1E-4 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 4590 4640 0.035 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 2800 2820 0.12 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF08428 Rib/alpha-like repeat 2589 2638 0.081 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 19 53 4.1E-7 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 SUPERFAMILY SSF46997 834 900 1.36E-7 T 28-03-2018 IPR009063 Immunoglobulin/albumin-binding domain GO:0009405 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF04650 YSIRK type signal peptide 20 44 1.5E-5 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.10.8.40 526 574 2.6E-4 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.5.420 784 835 1.3E-6 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 5649 5679 2.9E-5 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.1270.90 911 991 4.1E-13 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF00746 LPXTG cell wall anchor motif 5645 5683 5.3E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 SMART SM00844 572 628 0.0076 T 28-03-2018 IPR020840 Extracellular matrix-binding protein ebh, GA module CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 SMART SM00844 630 678 0.33 T 28-03-2018 IPR020840 Extracellular matrix-binding protein ebh, GA module CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.5.420 836 901 8.6E-9 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.5.420 738 783 0.13 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.5.420 1268 1322 0.067 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.5.420 4482 4548 0.16 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.5.420 4061 4128 0.16 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.5.420 4692 4744 0.15 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:1.20.5.420 636 685 8.2E-7 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF01468 GA module 577 628 2.4E-6 T 28-03-2018 IPR002988 Protein G-related albumin-binding (GA) module GO:0009405 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF07554 FIVAR domain 834 899 6.9E-10 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Pfam PF07554 FIVAR domain 912 982 8.8E-9 T 28-03-2018 CWM22_RS03395 565820fb5bd39e81bb39447dcd004dd0 5683 Gene3D G3DSA:3.90.182.10 3963 4050 1.8E-17 T 28-03-2018 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Gene3D G3DSA:1.10.8.60 373 496 1.1E-26 T 28-03-2018 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Gene3D G3DSA:1.10.1780.10 1 176 1.1E-12 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 102 129 8.4E-5 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 14 56 0.24 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 550 568 6.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 595 613 6.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 624 642 6.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 657 671 6.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Gene3D G3DSA:3.40.50.300 501 722 6.8E-52 T 28-03-2018 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 324 336 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 580 598 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 SMART SM01086 723 812 2.2E-28 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 233 365 6.3E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 SUPERFAMILY SSF81923 4 130 3.43E-10 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Gene3D G3DSA:1.10.8.60 723 817 1.1E-21 T 28-03-2018 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 723 802 3.4E-21 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Gene3D G3DSA:3.40.50.300 188 372 3.8E-22 T 28-03-2018 CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 SMART SM00382 546 686 2.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 SMART SM00382 228 374 1.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 SUPERFAMILY SSF52540 495 804 1.49E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 SUPERFAMILY SSF52540 191 443 1.02E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11915 bce0603e335ee5a3a7e81483acc8dc86 817 Pfam PF07724 AAA domain (Cdc48 subfamily) 545 716 2.5E-53 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS12245 88ec2adb58c800683812a10f89236c11 120 SMART SM00422 1 68 1.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS12245 88ec2adb58c800683812a10f89236c11 120 Gene3D G3DSA:1.10.1660.10 1 53 7.2E-12 T 28-03-2018 CWM22_RS12245 88ec2adb58c800683812a10f89236c11 120 Gene3D G3DSA:1.10.1660.10 54 119 8.1E-7 T 28-03-2018 CWM22_RS12245 88ec2adb58c800683812a10f89236c11 120 Pfam PF13411 MerR HTH family regulatory protein 1 64 1.4E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS12245 88ec2adb58c800683812a10f89236c11 120 SUPERFAMILY SSF46955 1 111 4.4E-16 T 28-03-2018 IPR009061 Putative DNA-binding domain CWM22_RS05585 7ab85085205029e8d27e7fb94d1ffed5 557 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 120 340 6.4E-43 T 28-03-2018 IPR000477 Reverse transcriptase domain CWM22_RS05585 7ab85085205029e8d27e7fb94d1ffed5 557 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 69 423 4.4E-104 T 28-03-2018 IPR030931 Group II intron reverse transcriptase/maturase CWM22_RS05585 7ab85085205029e8d27e7fb94d1ffed5 557 SUPERFAMILY SSF56672 85 426 2.22E-51 T 28-03-2018 CWM22_RS05585 7ab85085205029e8d27e7fb94d1ffed5 557 Pfam PF08388 Group II intron, maturase-specific domain 363 436 1.9E-20 T 28-03-2018 IPR013597 Group II intron, maturase-specific CWM22_RS05585 7ab85085205029e8d27e7fb94d1ffed5 557 Pfam PF13655 N-terminal domain of reverse transcriptase 24 104 2.5E-33 T 28-03-2018 IPR025960 Reverse transcriptase, N-terminal domain CWM22_RS05585 7ab85085205029e8d27e7fb94d1ffed5 557 Gene3D G3DSA:3.40.1800.10 492 552 2.5E-5 T 28-03-2018 CWM22_RS05585 7ab85085205029e8d27e7fb94d1ffed5 557 Gene3D G3DSA:3.30.70.270 154 340 1.4E-29 T 28-03-2018 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 Pfam PF02378 Phosphotransferase system, EIIC 15 378 8.6E-53 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 Gene3D G3DSA:2.70.70.10 562 722 3.7E-54 T 28-03-2018 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 578 696 9.9E-40 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 SUPERFAMILY SSF55604 473 546 6.02E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 Gene3D G3DSA:3.30.1360.60 470 546 1.4E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 SUPERFAMILY SSF51261 574 719 1.01E-49 T 28-03-2018 IPR011055 Duplicated hybrid motif CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 485 502 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 575 699 8.7E-48 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 438 532 1.2E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 4 548 1.1E-291 T 28-03-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 Pfam PF00367 phosphotransferase system, EIIB 475 506 8.0E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWM22_RS02350 49ee3ae3c0327474fa4999cc0419691a 722 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 638 650 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS00610 f963e06024c88d1f5d03cce62cab759d 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00610 f963e06024c88d1f5d03cce62cab759d 38 Pfam PF00444 Ribosomal protein L36 1 38 6.2E-22 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00610 f963e06024c88d1f5d03cce62cab759d 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.368 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00610 f963e06024c88d1f5d03cce62cab759d 38 SUPERFAMILY SSF57840 1 38 1.18E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00610 f963e06024c88d1f5d03cce62cab759d 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 8.6E-23 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00610 f963e06024c88d1f5d03cce62cab759d 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 38 3.0E-10 T 28-03-2018 CWM22_RS02470 42cde02b62b03eb0a4ba0c49849773e3 206 Gene3D G3DSA:3.30.63.10 52 83 8.3E-25 T 28-03-2018 CWM22_RS02470 42cde02b62b03eb0a4ba0c49849773e3 206 SMART SM00072 4 187 3.3E-72 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CWM22_RS02470 42cde02b62b03eb0a4ba0c49849773e3 206 SUPERFAMILY SSF52540 3 190 7.96E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02470 42cde02b62b03eb0a4ba0c49849773e3 206 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 37.018 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CWM22_RS02470 42cde02b62b03eb0a4ba0c49849773e3 206 Pfam PF00625 Guanylate kinase 7 186 6.6E-52 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CWM22_RS02470 42cde02b62b03eb0a4ba0c49849773e3 206 Gene3D G3DSA:3.40.50.300 1 51 1.7E-8 T 28-03-2018 CWM22_RS02470 42cde02b62b03eb0a4ba0c49849773e3 206 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 1.3E-72 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CWM22_RS02470 42cde02b62b03eb0a4ba0c49849773e3 206 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CWM22_RS02470 42cde02b62b03eb0a4ba0c49849773e3 206 Gene3D G3DSA:3.40.50.300 84 187 5.6E-29 T 28-03-2018 CWM22_RS09210 82fb70afa6b89109efec0ccca1383ec3 437 SUPERFAMILY SSF53756 1 346 1.18E-73 T 28-03-2018 CWM22_RS09210 82fb70afa6b89109efec0ccca1383ec3 437 Gene3D G3DSA:3.40.50.2000 1 193 7.3E-18 T 28-03-2018 CWM22_RS09210 82fb70afa6b89109efec0ccca1383ec3 437 Pfam PF13439 Glycosyltransferase Family 4 15 182 1.0E-33 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CWM22_RS09210 82fb70afa6b89109efec0ccca1383ec3 437 Gene3D G3DSA:3.40.50.2000 194 351 1.5E-36 T 28-03-2018 CWM22_RS09210 82fb70afa6b89109efec0ccca1383ec3 437 Pfam PF00534 Glycosyl transferases group 1 194 341 8.5E-31 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWM22_RS05770 94158eb7950fc10ec9ea532bf0e82bbc 245 Gene3D G3DSA:3.40.50.150 1 183 9.2E-37 T 28-03-2018 CWM22_RS05770 94158eb7950fc10ec9ea532bf0e82bbc 245 Gene3D G3DSA:1.10.8.100 184 242 3.8E-31 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CWM22_RS05770 94158eb7950fc10ec9ea532bf0e82bbc 245 SMART SM00650 17 179 2.4E-60 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CWM22_RS05770 94158eb7950fc10ec9ea532bf0e82bbc 245 SUPERFAMILY SSF53335 1 238 2.84E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS05770 94158eb7950fc10ec9ea532bf0e82bbc 245 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 60 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CWM22_RS05770 94158eb7950fc10ec9ea532bf0e82bbc 245 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 239 4.2E-76 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CWM22_RS05640 94158eb7950fc10ec9ea532bf0e82bbc 245 Gene3D G3DSA:3.40.50.150 1 183 9.2E-37 T 28-03-2018 CWM22_RS05640 94158eb7950fc10ec9ea532bf0e82bbc 245 Gene3D G3DSA:1.10.8.100 184 242 3.8E-31 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CWM22_RS05640 94158eb7950fc10ec9ea532bf0e82bbc 245 SMART SM00650 17 179 2.4E-60 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CWM22_RS05640 94158eb7950fc10ec9ea532bf0e82bbc 245 SUPERFAMILY SSF53335 1 238 2.84E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS05640 94158eb7950fc10ec9ea532bf0e82bbc 245 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 60 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CWM22_RS05640 94158eb7950fc10ec9ea532bf0e82bbc 245 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 239 4.2E-76 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CWM22_RS09690 caf57cd49f9ad281774dc83139ecaa1e 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS00780 caf57cd49f9ad281774dc83139ecaa1e 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS06830 caf57cd49f9ad281774dc83139ecaa1e 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS00310 caf57cd49f9ad281774dc83139ecaa1e 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS03500 7f49249d275f90b0deb8a5e57e266bb0 412 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 319 340 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CWM22_RS03500 7f49249d275f90b0deb8a5e57e266bb0 412 SUPERFAMILY SSF53720 6 412 2.36E-111 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWM22_RS03500 7f49249d275f90b0deb8a5e57e266bb0 412 Gene3D G3DSA:3.40.605.10 2 236 9.2E-38 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWM22_RS03500 7f49249d275f90b0deb8a5e57e266bb0 412 PIRSF PIRSF000151 1 412 4.3E-173 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CWM22_RS03500 7f49249d275f90b0deb8a5e57e266bb0 412 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 412 40.065 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CWM22_RS03500 7f49249d275f90b0deb8a5e57e266bb0 412 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 15 402 1.6E-147 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CWM22_RS03500 7f49249d275f90b0deb8a5e57e266bb0 412 Pfam PF00171 Aldehyde dehydrogenase family 19 278 2.7E-15 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWM22_RS03500 7f49249d275f90b0deb8a5e57e266bb0 412 Gene3D G3DSA:3.40.605.10 237 412 5.3E-40 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 Gene3D G3DSA:1.10.1420.10 17 285 0.0024 T 28-03-2018 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 SUPERFAMILY SSF48334 24 283 3.92E-31 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 SMART SM00463 699 777 1.5E-19 T 28-03-2018 IPR002625 Smr domain CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 SMART SM00533 9 310 1.1E-6 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 Pfam PF01713 Smr domain 702 777 4.2E-19 T 28-03-2018 IPR002625 Smr domain CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 403 419 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 776 19.704 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 Gene3D G3DSA:3.40.50.300 287 557 1.5E-32 T 28-03-2018 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 SMART SM00534 321 506 2.2E-65 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 776 1.7E-202 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 PIRSF PIRSF005814 1 777 4.9E-251 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 SUPERFAMILY SSF52540 287 507 4.08E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 SUPERFAMILY SSF160443 700 776 9.68E-10 T 28-03-2018 IPR002625 Smr domain CWM22_RS01430 8d88a6ba1ef05b3be12f7bde5f4e4796 777 Pfam PF00488 MutS domain V 324 504 2.1E-33 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWM22_RS02120 8bf03e29085611cdf693e30e77a1a043 150 Gene3D G3DSA:3.40.50.620 1 150 3.3E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS02120 8bf03e29085611cdf693e30e77a1a043 150 SUPERFAMILY SSF52402 5 146 7.2E-32 T 28-03-2018 CWM22_RS02120 8bf03e29085611cdf693e30e77a1a043 150 Pfam PF00582 Universal stress protein family 5 144 1.3E-34 T 28-03-2018 IPR006016 UspA GO:0006950 CWM22_RS02120 8bf03e29085611cdf693e30e77a1a043 150 PRINTS PR01438 Universal stress protein signature 5 23 1.1E-17 T 28-03-2018 IPR006015 Universal stress protein A CWM22_RS02120 8bf03e29085611cdf693e30e77a1a043 150 PRINTS PR01438 Universal stress protein signature 122 144 1.1E-17 T 28-03-2018 IPR006015 Universal stress protein A CWM22_RS02120 8bf03e29085611cdf693e30e77a1a043 150 PRINTS PR01438 Universal stress protein signature 104 116 1.1E-17 T 28-03-2018 IPR006015 Universal stress protein A CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 Gene3D G3DSA:3.30.70.1450 437 512 4.0E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 SUPERFAMILY SSF116726 436 509 3.14E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 PRINTS PR00762 Chloride channel signature 163 182 9.1E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 PRINTS PR00762 Chloride channel signature 384 403 9.1E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 PRINTS PR00762 Chloride channel signature 366 382 9.1E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 PRINTS PR00762 Chloride channel signature 83 100 9.1E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 PRINTS PR00762 Chloride channel signature 331 351 9.1E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 SUPERFAMILY SSF81340 10 432 2.88E-104 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 Gene3D G3DSA:1.10.3080.10 2 436 7.9E-83 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 Pfam PF02080 TrkA-C domain 445 509 4.0E-7 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWM22_RS07090 4d69fe4d1378d60c95532271e19e633a 512 Pfam PF00654 Voltage gated chloride channel 71 416 5.0E-86 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 Gene3D G3DSA:1.10.287.130 227 313 8.6E-9 T 28-03-2018 CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 Gene3D G3DSA:3.30.565.10 314 455 7.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 SUPERFAMILY SSF55874 306 450 3.93E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 SUPERFAMILY SSF47384 221 299 4.9E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 451 2.8E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 SMART SM00387 345 452 2.2E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 SMART SM00304 169 221 4.2E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 9.1E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 9.1E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 SMART SM00388 236 302 2.6E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS02920 cbd51b5d8042127929c34a9f23d9ef88 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 318 5.9E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS00555 3aa25105365669b31c12a03f07113f33 180 Gene3D G3DSA:3.30.1440.10 2 180 2.3E-77 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00555 3aa25105365669b31c12a03f07113f33 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00555 3aa25105365669b31c12a03f07113f33 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.717 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00555 3aa25105365669b31c12a03f07113f33 180 Pfam PF00281 Ribosomal protein L5 25 81 7.0E-26 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00555 3aa25105365669b31c12a03f07113f33 180 Pfam PF00673 ribosomal L5P family C-terminus 86 178 7.0E-40 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00555 3aa25105365669b31c12a03f07113f33 180 PIRSF PIRSF002161 1 180 1.5E-65 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00555 3aa25105365669b31c12a03f07113f33 180 SUPERFAMILY SSF55282 4 179 3.53E-75 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS03700 573202fabafe0293c7836c0ee7b441b1 324 Gene3D G3DSA:3.40.50.10680 84 323 6.3E-50 T 28-03-2018 CWM22_RS03700 573202fabafe0293c7836c0ee7b441b1 324 SUPERFAMILY SSF142338 3 317 1.57E-96 T 28-03-2018 CWM22_RS03700 573202fabafe0293c7836c0ee7b441b1 324 Hamap MF_00973 Gluconeogenesis factor. 2 322 33.685 T 28-03-2018 IPR010119 Gluconeogenesis factor CWM22_RS03700 573202fabafe0293c7836c0ee7b441b1 324 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 6 321 4.6E-118 T 28-03-2018 IPR010119 Gluconeogenesis factor CWM22_RS03700 573202fabafe0293c7836c0ee7b441b1 324 Pfam PF01933 Uncharacterised protein family UPF0052 6 297 1.2E-91 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CWM22_RS11775 873cf14395104f908c5d0d461c5b4079 294 SMART SM00382 26 202 5.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11775 873cf14395104f908c5d0d461c5b4079 294 Pfam PF00005 ABC transporter 18 153 4.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS11775 873cf14395104f908c5d0d461c5b4079 294 Gene3D G3DSA:3.40.50.300 1 246 9.0E-50 T 28-03-2018 CWM22_RS11775 873cf14395104f908c5d0d461c5b4079 294 SUPERFAMILY SSF52540 2 206 2.19E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09855 91f0febd16adcf4c91653e6ac0d6e200 256 Pfam PF00717 Peptidase S24-like 180 240 4.6E-9 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWM22_RS09855 91f0febd16adcf4c91653e6ac0d6e200 256 Gene3D G3DSA:1.10.260.40 3 141 8.3E-12 T 28-03-2018 CWM22_RS09855 91f0febd16adcf4c91653e6ac0d6e200 256 SUPERFAMILY SSF51306 138 254 9.03E-20 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWM22_RS09855 91f0febd16adcf4c91653e6ac0d6e200 256 Gene3D G3DSA:2.10.109.10 143 256 4.3E-19 T 28-03-2018 CWM22_RS09855 91f0febd16adcf4c91653e6ac0d6e200 256 Pfam PF01381 Helix-turn-helix 13 64 4.6E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS09855 91f0febd16adcf4c91653e6ac0d6e200 256 SUPERFAMILY SSF47413 4 69 3.1E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS09855 91f0febd16adcf4c91653e6ac0d6e200 256 SMART SM00530 12 67 4.1E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 494 1.1E-221 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 253 4.8E-84 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 451 2.2E-56 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 Gene3D G3DSA:3.30.420.40 1 250 1.1E-87 T 28-03-2018 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 PIRSF PIRSF000538 4 502 1.6E-170 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 Hamap MF_00186 Glycerol kinase [glpK]. 4 498 56.458 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 SUPERFAMILY SSF53067 256 494 4.21E-81 T 28-03-2018 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 Gene3D G3DSA:3.30.420.40 251 499 7.8E-73 T 28-03-2018 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 SUPERFAMILY SSF53067 5 255 3.89E-95 T 28-03-2018 CWM22_RS07455 af5767e98480103982698b9a2cd78df8 504 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWM22_RS13145 94f0cb83b51e1b9dd74ef9c6fa5468c9 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 273 6.6E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS13145 94f0cb83b51e1b9dd74ef9c6fa5468c9 280 SUPERFAMILY SSF161098 8 280 2.34E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS13145 94f0cb83b51e1b9dd74ef9c6fa5468c9 280 Gene3D G3DSA:1.10.3720.10 1 267 2.0E-35 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1145 1199 1.8E-6 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF04650 YSIRK type signal peptide 9 33 1.3E-7 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 2780 2813 340.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 2390 2423 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 3105 3138 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 3040 3073 340.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 2325 2358 280.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 2260 2293 97.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 2975 3008 500.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 2910 2943 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 2845 2878 460.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 2585 2618 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 SMART SM00028 2650 2683 500.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2594 2658 1.2E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1143 1210 9.9E-12 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2659 2723 4.2E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1596 1666 1.5E-9 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2529 2593 1.8E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1879 1939 2.1E-5 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 3189 3246 1.7E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1216 1287 1.4E-8 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 3114 3182 4.1E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2919 2983 1.3E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2204 2263 3.0E-9 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2984 3044 1.2E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2269 2329 2.0E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2724 2788 1.5E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1672 1742 5.7E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2464 2524 2.4E-8 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 3049 3112 2.7E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2009 2072 1.1E-5 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1444 1514 9.4E-13 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2399 2458 1.5E-5 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1292 1362 9.4E-13 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2854 2918 3.5E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2334 2398 2.3E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1368 1438 1.7E-12 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1520 1590 4.1E-14 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2139 2199 1.1E-7 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 2789 2853 4.6E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF07564 Domain of Unknown Function (DUF1542) 1748 1822 8.9E-8 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1887 1940 1.3E-5 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 4 38 3.3E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:3.90.1810.10 3330 3424 4.4E-6 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2208 2264 1.4E-7 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1747 1815 0.0078 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 3455 3488 2.9E-5 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Pfam PF00746 LPXTG cell wall anchor motif 3449 3488 2.3E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2337 2394 5.7E-6 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2662 2718 2.6E-6 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2272 2328 2.2E-6 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 3117 3191 5.1E-7 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1513 1581 3.5E-9 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1676 1746 2.0E-6 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 3052 3109 4.1E-7 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2402 2463 2.1E-4 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1947 2002 1.3E-4 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2727 2784 1.8E-6 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2142 2204 6.6E-4 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1211 1277 0.0078 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1592 1656 0.0096 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2532 2589 2.1E-7 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2467 2529 6.3E-4 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2077 2136 0.0069 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1437 1505 3.7E-8 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1361 1429 3.7E-8 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 3193 3245 7.4E-9 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2857 2914 1.3E-7 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 1285 1353 3.8E-8 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2922 2979 3.2E-7 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2597 2654 3.2E-7 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2987 3043 2.4E-6 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2012 2076 0.061 T 28-03-2018 CWM22_RS01130 4bcadfaa45d38fa78b7b9691f9fd4a03 3492 Gene3D G3DSA:1.20.5.420 2792 2848 1.4E-7 T 28-03-2018 CWM22_RS04205 1761b4146816500ca601df11e0b7af95 153 SUPERFAMILY SSF52218 5 149 9.08E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS04205 1761b4146816500ca601df11e0b7af95 153 Gene3D G3DSA:3.40.50.360 3 152 1.4E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS04205 1761b4146816500ca601df11e0b7af95 153 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CWM22_RS04205 1761b4146816500ca601df11e0b7af95 153 Pfam PF00258 Flavodoxin 6 131 4.2E-19 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CWM22_RS04205 1761b4146816500ca601df11e0b7af95 153 TIGRFAM TIGR01753 flav_short: flavodoxin 5 145 1.2E-40 T 28-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 CWM22_RS13005 d117121d4dd1cdf49c2f569fc702c870 723 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 127 717 3.4E-185 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CWM22_RS13005 d117121d4dd1cdf49c2f569fc702c870 723 ProSitePatterns PS00850 Glycine radical domain signature. 688 696 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CWM22_RS13005 d117121d4dd1cdf49c2f569fc702c870 723 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 128 717 1.0E-181 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CWM22_RS13005 d117121d4dd1cdf49c2f569fc702c870 723 Pfam PF03477 ATP cone domain 14 102 5.2E-18 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CWM22_RS13005 d117121d4dd1cdf49c2f569fc702c870 723 SUPERFAMILY SSF51998 133 699 5.04E-196 T 28-03-2018 CWM22_RS13005 d117121d4dd1cdf49c2f569fc702c870 723 Gene3D G3DSA:3.20.70.20 133 699 9.0E-203 T 28-03-2018 CWM22_RS02065 8a47cfad0e39aab8fe421449b2024d5c 62 Gene3D G3DSA:2.30.170.40 2 62 3.7E-19 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02065 8a47cfad0e39aab8fe421449b2024d5c 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 4.3E-21 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS02065 8a47cfad0e39aab8fe421449b2024d5c 62 SUPERFAMILY SSF143800 1 60 1.28E-23 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02065 8a47cfad0e39aab8fe421449b2024d5c 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 17.935 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS02065 8a47cfad0e39aab8fe421449b2024d5c 62 Pfam PF00830 Ribosomal L28 family 3 58 7.5E-21 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 Pfam PF00580 UvrD/REP helicase N-terminal domain 40 482 1.4E-76 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 39 1220 0.0 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 SUPERFAMILY SSF52540 38 210 7.06E-115 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 SUPERFAMILY SSF52540 377 838 7.06E-115 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 SUPERFAMILY SSF52540 888 913 7.06E-115 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1048 1204 6.0E-9 T 28-03-2018 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 Gene3D G3DSA:3.40.50.300 497 630 1.2E-17 T 28-03-2018 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 Pfam PF13361 UvrD-like helicase C-terminal domain 494 908 5.6E-32 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 Gene3D G3DSA:3.90.320.10 966 1212 9.1E-29 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 Gene3D G3DSA:1.10.486.10 631 800 4.5E-27 T 28-03-2018 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 36 1224 17.011 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 Gene3D G3DSA:3.40.50.300 29 495 6.7E-44 T 28-03-2018 CWM22_RS07325 36b636afb70b3e777e45a199eb298190 1227 SUPERFAMILY SSF52980 1023 1205 2.68E-27 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 SUPERFAMILY SSF46785 3 63 1.82E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 Hamap MF_00173 Arginine repressor [argR]. 1 152 50.856 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 Gene3D G3DSA:3.30.1360.40 74 146 4.5E-20 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 Gene3D G3DSA:1.10.10.10 5 66 6.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 Pfam PF02863 Arginine repressor, C-terminal domain 81 146 6.0E-19 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 91 126 2.0E-12 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 Pfam PF01316 Arginine repressor, DNA binding domain 5 63 5.5E-20 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 PRINTS PR01467 Bacterial arginine repressor signature 88 101 2.1E-17 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 PRINTS PR01467 Bacterial arginine repressor signature 38 53 2.1E-17 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 PRINTS PR01467 Bacterial arginine repressor signature 118 133 2.1E-17 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 PRINTS PR01467 Bacterial arginine repressor signature 22 35 2.1E-17 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS03745 dac16dc3fe66ffdd795ffdc761b412d9 157 SUPERFAMILY SSF55252 79 148 7.85E-20 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Gene3D G3DSA:3.20.20.80 809 1095 7.5E-118 T 28-03-2018 CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Gene3D G3DSA:2.70.98.10 538 806 1.8E-83 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Gene3D G3DSA:2.60.120.260 1260 1422 7.1E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Gene3D G3DSA:2.60.120.260 1423 1625 1.8E-54 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Pfam PF17451 Glycosyl hydrolase 101 beta sandwich domain 1092 1226 6.2E-39 T 28-03-2018 IPR035364 Glycosyl hydrolase 101, beta-sandwich domain CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Gene3D G3DSA:2.60.40.1180 1096 1252 1.0E-50 T 28-03-2018 CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 8 41 2.3E-12 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 SUPERFAMILY SSF49785 1701 1827 9.28E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Pfam PF04650 YSIRK type signal peptide 11 34 5.1E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Pfam PF12905 Endo-alpha-N-acetylgalactosaminidase 796 1086 8.5E-122 T 28-03-2018 IPR025706 Endo-alpha-N-acetylgalactosaminidase GO:0033926 CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Pfam PF00754 F5/8 type C domain 1706 1813 1.5E-11 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 Gene3D G3DSA:2.60.120.260 1683 1827 4.7E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS01270 ff09d7897073972eba26ed5dd5dd8d72 2020 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1988 2018 0.0015 T 28-03-2018 CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 Pfam PF02780 Transketolase, C-terminal domain 536 649 2.2E-14 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 ProSitePatterns PS00802 Transketolase signature 2. 464 480 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 SUPERFAMILY SSF52922 527 655 2.75E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 SUPERFAMILY SSF52518 342 522 2.73E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 Pfam PF02779 Transketolase, pyrimidine binding domain 352 521 1.8E-43 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 3 332 1.5E-148 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 SMART SM00861 351 522 6.2E-64 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 Gene3D G3DSA:3.40.50.970 347 532 1.2E-45 T 28-03-2018 CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 Gene3D G3DSA:3.40.50.970 1 346 2.3E-97 T 28-03-2018 CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 SUPERFAMILY SSF52518 4 321 8.97E-109 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 Gene3D G3DSA:3.40.50.920 533 656 1.7E-29 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 ProSitePatterns PS00801 Transketolase signature 1. 10 30 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWM22_RS12480 b72f7156586c21e0a9e20925ab445ecf 656 TIGRFAM TIGR00232 tktlase_bact: transketolase 5 654 6.6E-275 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CWM22_RS03550 4e026d38394f9c4db00de850bfc84131 608 Gene3D G3DSA:3.40.50.720 298 608 1.9E-63 T 28-03-2018 CWM22_RS03550 4e026d38394f9c4db00de850bfc84131 608 Pfam PF13727 CoA-binding domain 89 245 5.7E-12 T 28-03-2018 CWM22_RS03550 4e026d38394f9c4db00de850bfc84131 608 Gene3D G3DSA:3.40.50.720 259 297 0.011 T 28-03-2018 CWM22_RS03550 4e026d38394f9c4db00de850bfc84131 608 SUPERFAMILY SSF51735 287 551 1.01E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS03550 4e026d38394f9c4db00de850bfc84131 608 SUPERFAMILY SSF51735 147 277 3.94E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS03550 4e026d38394f9c4db00de850bfc84131 608 Pfam PF02719 Polysaccharide biosynthesis protein 290 571 8.4E-122 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CWM22_RS03550 4e026d38394f9c4db00de850bfc84131 608 Gene3D G3DSA:3.40.50.720 145 258 5.1E-29 T 28-03-2018 CWM22_RS01480 31fc71cac6a739f088c7402a22d12945 210 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS01480 31fc71cac6a739f088c7402a22d12945 210 SMART SM00382 26 202 4.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS01480 31fc71cac6a739f088c7402a22d12945 210 SUPERFAMILY SSF52540 3 208 1.85E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01480 31fc71cac6a739f088c7402a22d12945 210 TIGRFAM TIGR03608 L_ocin_972_ABC: putative bacteriocin export ABC transporter, lactococcin 972 group 4 207 7.3E-80 T 28-03-2018 IPR019895 Putative bacteriocin export ABC transporter, lactococcin 972 group CWM22_RS01480 31fc71cac6a739f088c7402a22d12945 210 Gene3D G3DSA:3.40.50.300 1 209 2.6E-58 T 28-03-2018 CWM22_RS01480 31fc71cac6a739f088c7402a22d12945 210 Pfam PF00005 ABC transporter 18 164 1.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS11590 5eb4cc66f55dd23a1af9320324eb6d22 401 Pfam PF01501 Glycosyl transferase family 8 5 231 1.9E-37 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CWM22_RS11590 5eb4cc66f55dd23a1af9320324eb6d22 401 SUPERFAMILY SSF53448 5 249 2.56E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS11590 5eb4cc66f55dd23a1af9320324eb6d22 401 Gene3D G3DSA:3.90.550.10 3 259 4.8E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 SMART SM00448 2 116 4.0E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 Pfam PF12833 Helix-turn-helix domain 344 421 9.4E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 SUPERFAMILY SSF52172 2 124 4.41E-36 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 Pfam PF00072 Response regulator receiver domain 5 116 1.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 Gene3D G3DSA:3.40.50.2300 2 236 4.8E-36 T 28-03-2018 CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 389 404 4.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 404 420 4.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 Gene3D G3DSA:3.90.1240.10 246 429 6.3E-26 T 28-03-2018 CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 SUPERFAMILY SSF46689 374 423 1.52E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 374 416 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWM22_RS11600 1c0ba1696c062f5bd33aa8cd689455fd 429 SMART SM00342 337 420 5.4E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWM22_RS09685 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS09685 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS09685 7f4e7072acacd299599c1068ee10048b 450 Pfam PF03050 Transposase IS66 family 117 393 7.6E-83 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS00315 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS00315 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS00315 7f4e7072acacd299599c1068ee10048b 450 Pfam PF03050 Transposase IS66 family 117 393 7.6E-83 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS08860 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS08860 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS08860 7f4e7072acacd299599c1068ee10048b 450 Pfam PF03050 Transposase IS66 family 117 393 7.6E-83 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS11985 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS11985 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS11985 7f4e7072acacd299599c1068ee10048b 450 Pfam PF03050 Transposase IS66 family 117 393 7.6E-83 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS08250 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS08250 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS08250 7f4e7072acacd299599c1068ee10048b 450 Pfam PF03050 Transposase IS66 family 117 393 7.6E-83 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS00775 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS00775 7f4e7072acacd299599c1068ee10048b 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS00775 7f4e7072acacd299599c1068ee10048b 450 Pfam PF03050 Transposase IS66 family 117 393 7.6E-83 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 Gene3D G3DSA:3.30.559.10 218 461 1.9E-77 T 28-03-2018 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 SUPERFAMILY SSF47005 165 204 2.35E-9 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 SUPERFAMILY SSF47005 119 162 4.19E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 SUPERFAMILY SSF52777 223 461 1.02E-75 T 28-03-2018 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 Pfam PF00364 Biotin-requiring enzyme 4 76 6.7E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 Gene3D G3DSA:4.10.320.10 119 165 1.2E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 Pfam PF02817 e3 binding domain 166 201 7.6E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 Pfam PF02817 e3 binding domain 124 159 3.7E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 Gene3D G3DSA:2.40.50.100 5 90 4.5E-14 T 28-03-2018 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 230 460 2.7E-74 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 SUPERFAMILY SSF51230 1 91 1.48E-25 T 28-03-2018 IPR011053 Single hybrid motif CWM22_RS11190 f09a7269b20e4d5e8ca0998358ae4ed4 461 Gene3D G3DSA:4.10.320.10 166 217 1.8E-15 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 Gene3D G3DSA:2.60.40.1180 539 612 4.0E-8 T 28-03-2018 CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 SUPERFAMILY SSF51011 524 611 2.08E-8 T 28-03-2018 CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 SUPERFAMILY SSF51445 86 514 2.19E-94 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 SMART SM00642 152 508 4.4E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 23 105 6.6E-17 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 Pfam PF00128 Alpha amylase, catalytic domain 191 255 6.8E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 528 609 2.1E-6 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 SUPERFAMILY SSF81296 16 120 2.45E-23 T 28-03-2018 IPR014756 Immunoglobulin E-set CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 PIRSF PIRSF000463 1 588 4.1E-202 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 Gene3D G3DSA:2.60.40.10 1 120 7.5E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 8 581 1.5E-185 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CWM22_RS05935 6e558bd8406fc0836646f0725014c4d4 612 Gene3D G3DSA:3.20.20.80 138 538 3.0E-66 T 28-03-2018 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 SMART SM00474 304 466 4.3E-12 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 SMART SM00279 180 215 5.6E-17 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 SMART SM00482 634 842 5.9E-117 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 SUPERFAMILY SSF88723 3 177 2.94E-50 T 28-03-2018 IPR029060 PIN domain-like CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 Gene3D G3DSA:3.30.70.370 704 878 1.6E-50 T 28-03-2018 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 Gene3D G3DSA:3.30.70.370 602 692 1.5E-14 T 28-03-2018 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 SMART SM00475 4 269 2.5E-149 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 Pfam PF00476 DNA polymerase family A 498 876 1.2E-150 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 649 672 2.1E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 626 641 2.1E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 679 692 2.1E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 704 729 2.1E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 795 811 2.1E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 741 752 2.1E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 763 774 2.1E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 825 838 2.1E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 603 625 2.1E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 ProSitePatterns PS00447 DNA polymerase family A signature. 704 723 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 Gene3D G3DSA:1.20.1060.10 422 601 1.3E-50 T 28-03-2018 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 178 272 1.9E-33 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 SUPERFAMILY SSF53098 302 468 4.8E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 177 6.7E-51 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 TIGRFAM TIGR00593 pola: DNA polymerase I 6 878 0.0 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 Gene3D G3DSA:3.40.50.1010 4 191 7.7E-64 T 28-03-2018 IPR029060 PIN domain-like CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 SUPERFAMILY SSF56672 470 878 3.45E-149 T 28-03-2018 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 Gene3D G3DSA:1.10.150.20 192 270 1.2E-30 T 28-03-2018 CWM22_RS09255 a08c9347d8b44fe3d796b24ceb0b3e90 878 SUPERFAMILY SSF47807 178 292 4.04E-34 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 SUPERFAMILY SSF56300 29 368 3.8E-55 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 Gene3D G3DSA:3.60.21.10 23 370 6.1E-55 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 PRINTS PR01607 Apyrase family signature 31 49 8.5E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 PRINTS PR01607 Apyrase family signature 305 325 8.5E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 PRINTS PR01607 Apyrase family signature 246 263 8.5E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 PRINTS PR01607 Apyrase family signature 279 302 8.5E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 PRINTS PR01607 Apyrase family signature 508 527 8.5E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 PRINTS PR01607 Apyrase family signature 433 456 8.5E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 640 672 0.001 T 28-03-2018 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 Gene3D G3DSA:3.90.780.10 371 574 6.5E-44 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 Pfam PF00149 Calcineurin-like phosphoesterase 35 297 3.8E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 Pfam PF02872 5'-nucleotidase, C-terminal domain 371 535 6.8E-34 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS03875 0783284b612cd4d0a828a1dc2e33d292 674 SUPERFAMILY SSF55816 370 574 2.75E-42 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS02800 64c0ad5f8186e6492c95d58ba4bf411c 535 Gene3D G3DSA:3.90.350.10 122 438 1.0E-38 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS02800 64c0ad5f8186e6492c95d58ba4bf411c 535 SUPERFAMILY SSF53098 323 466 9.86E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS02800 64c0ad5f8186e6492c95d58ba4bf411c 535 Pfam PF01609 Transposase DDE domain 167 455 2.7E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS01315 64c0ad5f8186e6492c95d58ba4bf411c 535 Gene3D G3DSA:3.90.350.10 122 438 1.0E-38 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS01315 64c0ad5f8186e6492c95d58ba4bf411c 535 SUPERFAMILY SSF53098 323 466 9.86E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS01315 64c0ad5f8186e6492c95d58ba4bf411c 535 Pfam PF01609 Transposase DDE domain 167 455 2.7E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS04235 64c0ad5f8186e6492c95d58ba4bf411c 535 Gene3D G3DSA:3.90.350.10 122 438 1.0E-38 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS04235 64c0ad5f8186e6492c95d58ba4bf411c 535 SUPERFAMILY SSF53098 323 466 9.86E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS04235 64c0ad5f8186e6492c95d58ba4bf411c 535 Pfam PF01609 Transposase DDE domain 167 455 2.7E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS06635 64c0ad5f8186e6492c95d58ba4bf411c 535 Gene3D G3DSA:3.90.350.10 122 438 1.0E-38 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS06635 64c0ad5f8186e6492c95d58ba4bf411c 535 SUPERFAMILY SSF53098 323 466 9.86E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS06635 64c0ad5f8186e6492c95d58ba4bf411c 535 Pfam PF01609 Transposase DDE domain 167 455 2.7E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS09465 64c0ad5f8186e6492c95d58ba4bf411c 535 Gene3D G3DSA:3.90.350.10 122 438 1.0E-38 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS09465 64c0ad5f8186e6492c95d58ba4bf411c 535 SUPERFAMILY SSF53098 323 466 9.86E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS09465 64c0ad5f8186e6492c95d58ba4bf411c 535 Pfam PF01609 Transposase DDE domain 167 455 2.7E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS10835 64c0ad5f8186e6492c95d58ba4bf411c 535 Gene3D G3DSA:3.90.350.10 122 438 1.0E-38 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS10835 64c0ad5f8186e6492c95d58ba4bf411c 535 SUPERFAMILY SSF53098 323 466 9.86E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS10835 64c0ad5f8186e6492c95d58ba4bf411c 535 Pfam PF01609 Transposase DDE domain 167 455 2.7E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 35 1117 28.673 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SMART SM01058 488 585 9.7E-45 T 28-03-2018 IPR003711 CarD-like/TRCF domain CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 Gene3D G3DSA:3.40.50.300 798 965 8.6E-23 T 28-03-2018 CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SUPERFAMILY SSF52540 791 995 7.03E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SUPERFAMILY SSF143517 999 1158 5.23E-31 T 28-03-2018 CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 Gene3D G3DSA:3.30.2060.10 140 218 0.0013 T 28-03-2018 CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SUPERFAMILY SSF52540 15 360 2.04E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 Gene3D G3DSA:3.40.50.300 299 782 2.3E-36 T 28-03-2018 CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 Pfam PF03461 TRCF domain 1014 1099 9.2E-23 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 156 1079 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SMART SM00490 835 919 2.2E-17 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SUPERFAMILY SSF141259 479 557 9.15E-24 T 28-03-2018 IPR003711 CarD-like/TRCF domain CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SUPERFAMILY SSF52540 369 478 2.55E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 Pfam PF00271 Helicase conserved C-terminal domain 815 918 3.1E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SUPERFAMILY SSF52540 533 792 6.19E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 Pfam PF02559 CarD-like/TRCF domain 489 584 1.2E-27 T 28-03-2018 IPR003711 CarD-like/TRCF domain CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SMART SM00487 609 799 2.8E-37 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 SMART SM00982 1013 1108 9.1E-32 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CWM22_RS00040 8942ca09ea4ae2b36182e8d37cf6c742 1164 Pfam PF00270 DEAD/DEAH box helicase 614 775 3.1E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWM22_RS10610 51e9318020d136f921a843b77810e4e1 316 Gene3D G3DSA:1.10.150.170 116 221 9.1E-40 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS10610 51e9318020d136f921a843b77810e4e1 316 SUPERFAMILY SSF53335 6 117 1.22E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS10610 51e9318020d136f921a843b77810e4e1 316 SUPERFAMILY SSF53335 219 314 1.22E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS10610 51e9318020d136f921a843b77810e4e1 316 SUPERFAMILY SSF81799 118 219 1.83E-35 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS10610 51e9318020d136f921a843b77810e4e1 316 Pfam PF01795 MraW methylase family 4 313 5.1E-131 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS10610 51e9318020d136f921a843b77810e4e1 316 PIRSF PIRSF004486 1 315 8.0E-106 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS10610 51e9318020d136f921a843b77810e4e1 316 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 37.341 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS10610 51e9318020d136f921a843b77810e4e1 316 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 313 1.4E-117 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS10610 51e9318020d136f921a843b77810e4e1 316 Gene3D G3DSA:3.40.50.150 2 102 2.1E-7 T 28-03-2018 CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 173 196 1.0E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 551 578 3.8E-7 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 496 522 1.0E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 255 280 1.8E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 538 564 2.2E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 Gene3D G3DSA:1.20.1480.30 312 481 0.0092 T 28-03-2018 CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 SUPERFAMILY SSF101967 176 296 1.11E-5 T 28-03-2018 CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 617 815 1.6E-70 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 Pfam PF12051 Protein of unknown function (DUF3533) 23 174 2.6E-9 T 28-03-2018 IPR022703 Domain of unknown function DUF3533 CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 Gene3D G3DSA:3.40.1710.10 41 211 3.5E-25 T 28-03-2018 CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 Gene3D G3DSA:1.20.120.570 482 621 2.3E-11 T 28-03-2018 CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 4 166 2.2E-63 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CWM22_RS01550 5a1929fcaa22834fcc13c675e10688b2 819 Gene3D G3DSA:1.10.287.950 212 305 2.3E-5 T 28-03-2018 CWM22_RS12725 eb8f63ee9fbd88cbf22a34d298a6738b 446 SUPERFAMILY SSF55874 309 423 8.08E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS12725 eb8f63ee9fbd88cbf22a34d298a6738b 446 Gene3D G3DSA:3.30.565.10 295 440 1.4E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS12725 eb8f63ee9fbd88cbf22a34d298a6738b 446 Pfam PF14501 GHKL domain 344 443 4.9E-14 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWM22_RS12725 eb8f63ee9fbd88cbf22a34d298a6738b 446 Gene3D G3DSA:1.10.287.130 230 291 3.3E-7 T 28-03-2018 CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 Gene3D G3DSA:3.40.50.150 722 1126 1.6E-31 T 28-03-2018 CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 SUPERFAMILY SSF52540 1597 1692 3.15E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 SUPERFAMILY SSF52540 1384 1536 3.15E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 723 739 4.1E-8 T 28-03-2018 CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 749 763 4.1E-8 T 28-03-2018 CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 809 821 4.1E-8 T 28-03-2018 CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 834 858 4.1E-8 T 28-03-2018 CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 SMART SM00487 1422 1693 4.4E-7 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 Pfam PF00271 Helicase conserved C-terminal domain 1835 1948 1.4E-5 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 Pfam PF04851 Type III restriction enzyme, res subunit 1424 1628 5.3E-8 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 Gene3D G3DSA:3.40.50.300 1638 1993 5.3E-21 T 28-03-2018 CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 SUPERFAMILY SSF52540 1752 2043 1.6E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 Gene3D G3DSA:3.40.50.300 1351 1630 2.1E-17 T 28-03-2018 CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 SUPERFAMILY SSF53335 714 922 1.73E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06155 10feee4970e3a6ebe52bcf4a324137e0 2423 SMART SM00490 1858 1948 0.0086 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS11200 1cfffcd3d370252686b43d0d992cdd45 331 SMART SM00861 7 182 1.1E-64 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWM22_RS11200 1cfffcd3d370252686b43d0d992cdd45 331 Pfam PF02780 Transketolase, C-terminal domain 197 320 3.3E-42 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CWM22_RS11200 1cfffcd3d370252686b43d0d992cdd45 331 SUPERFAMILY SSF52518 6 195 7.5E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWM22_RS11200 1cfffcd3d370252686b43d0d992cdd45 331 SUPERFAMILY SSF52922 193 329 6.02E-43 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWM22_RS11200 1cfffcd3d370252686b43d0d992cdd45 331 Gene3D G3DSA:3.40.50.920 198 329 6.2E-42 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWM22_RS11200 1cfffcd3d370252686b43d0d992cdd45 331 Gene3D G3DSA:3.40.50.970 3 197 3.1E-65 T 28-03-2018 CWM22_RS11200 1cfffcd3d370252686b43d0d992cdd45 331 Pfam PF02779 Transketolase, pyrimidine binding domain 7 181 8.0E-48 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 Pfam PF08279 HTH domain 5 57 1.4E-15 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 Gene3D G3DSA:3.30.930.10 55 252 7.7E-42 T 28-03-2018 CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 SUPERFAMILY SSF50037 265 308 3.25E-5 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 Pfam PF02237 Biotin protein ligase C terminal domain 263 308 8.7E-8 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 Gene3D G3DSA:1.10.10.10 2 54 2.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 83 308 9.7E-44 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 5 309 29.879 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 SUPERFAMILY SSF55681 68 247 1.99E-45 T 28-03-2018 CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 Gene3D G3DSA:2.30.30.100 263 306 8.0E-10 T 28-03-2018 CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 SUPERFAMILY SSF46785 3 58 2.19E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03080 560a75ac6aa55a954b23ae218d3c4eca 318 Pfam PF03099 Biotin/lipoate A/B protein ligase family 117 207 1.4E-9 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 6.6E-192 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 Pfam PF00709 Adenylosuccinate synthetase 4 420 4.1E-187 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 SMART SM00788 3 422 1.0E-301 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 Gene3D G3DSA:3.40.440.10 150 264 4.0E-30 T 28-03-2018 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 Gene3D G3DSA:3.40.440.10 1 149 4.3E-54 T 28-03-2018 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 215.7 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 Gene3D G3DSA:3.90.170.10 265 429 7.2E-70 T 28-03-2018 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWM22_RS11890 4ddea44d2b1ce4741d9ac7e448d649b7 430 SUPERFAMILY SSF52540 1 427 1.49E-178 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10425 852b91a09a5327b9d0aa245140376baa 443 PIRSF PIRSF005700 1 443 5.5E-177 T 28-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 CWM22_RS10425 852b91a09a5327b9d0aa245140376baa 443 Gene3D G3DSA:3.90.70.10 52 443 2.2E-127 T 28-03-2018 CWM22_RS10425 852b91a09a5327b9d0aa245140376baa 443 Pfam PF03051 Peptidase C1-like family 4 440 1.6E-203 T 28-03-2018 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 Reactome: R-HSA-983168 CWM22_RS10425 852b91a09a5327b9d0aa245140376baa 443 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 361 371 - T 28-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 CWM22_RS10425 852b91a09a5327b9d0aa245140376baa 443 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 63 74 - T 28-03-2018 IPR000169 Cysteine peptidase, cysteine active site CWM22_RS10425 852b91a09a5327b9d0aa245140376baa 443 SUPERFAMILY SSF54001 3 443 4.21E-128 T 28-03-2018 CWM22_RS05090 3c266cba493a34bee38d9726e1d83ea8 306 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 8 306 5.7E-100 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CWM22_RS05090 3c266cba493a34bee38d9726e1d83ea8 306 PIRSF PIRSF000545 1 306 5.9E-135 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CWM22_RS05090 3c266cba493a34bee38d9726e1d83ea8 306 Hamap MF_00215 Pantothenate kinase [coaA]. 1 306 149.488 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CWM22_RS05090 3c266cba493a34bee38d9726e1d83ea8 306 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 86 228 9.7E-16 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CWM22_RS05090 3c266cba493a34bee38d9726e1d83ea8 306 Gene3D G3DSA:3.40.50.300 5 306 1.2E-55 T 28-03-2018 CWM22_RS05090 3c266cba493a34bee38d9726e1d83ea8 306 SUPERFAMILY SSF52540 3 306 2.99E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02525 99e38266d2616b89717a871c662b6df2 123 Pfam PF00575 S1 RNA binding domain 2 73 2.9E-19 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWM22_RS02525 99e38266d2616b89717a871c662b6df2 123 Gene3D G3DSA:2.40.50.140 1 81 8.0E-26 T 28-03-2018 CWM22_RS02525 99e38266d2616b89717a871c662b6df2 123 SMART SM00316 2 73 5.9E-25 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS02525 99e38266d2616b89717a871c662b6df2 123 SUPERFAMILY SSF50249 1 81 1.79E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS10520 51cfa7edbcba2ebe5f0969b69a7d767c 299 Gene3D G3DSA:1.10.245.10 14 76 0.0081 T 28-03-2018 IPR003121 SWIB/MDM2 domain GO:0005515 CWM22_RS10520 51cfa7edbcba2ebe5f0969b69a7d767c 299 Gene3D G3DSA:3.40.50.300 100 292 1.3E-17 T 28-03-2018 CWM22_RS10520 51cfa7edbcba2ebe5f0969b69a7d767c 299 Pfam PF01695 IstB-like ATP binding protein 114 266 3.7E-13 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CWM22_RS10520 51cfa7edbcba2ebe5f0969b69a7d767c 299 SUPERFAMILY SSF52540 119 267 2.19E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10520 51cfa7edbcba2ebe5f0969b69a7d767c 299 Pfam PF07319 Primosomal protein DnaI N-terminus 1 90 1.5E-22 T 28-03-2018 IPR009928 Primosomal DnaI, N-terminal CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 SMART SM00852 4 172 4.6E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 Gene3D G3DSA:3.40.980.10 1 172 3.0E-39 T 28-03-2018 IPR001453 MoaB/Mog domain CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 392 2.5E-96 T 28-03-2018 IPR008135 Competence-induced protein CinA CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 393 123.621 T 28-03-2018 IPR008135 Competence-induced protein CinA CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 Pfam PF00994 Probable molybdopterin binding domain 5 170 8.1E-33 T 28-03-2018 IPR001453 MoaB/Mog domain CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 PIRSF PIRSF006728 1 393 3.2E-112 T 28-03-2018 IPR008135 Competence-induced protein CinA CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 SUPERFAMILY SSF53218 1 204 1.22E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 Gene3D G3DSA:3.90.950.20 249 310 1.5E-5 T 28-03-2018 CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 Gene3D G3DSA:3.90.950.20 315 393 0.0021 T 28-03-2018 CWM22_RS00450 7032f3a5950755a28c9c70c0f0344c76 393 SUPERFAMILY SSF142433 252 392 5.62E-9 T 28-03-2018 IPR008136 CinA, C-terminal CWM22_RS07315 105489699a86ce4af2ea7c17b88e998a 214 SMART SM01207 9 194 3.8E-79 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWM22_RS07315 105489699a86ce4af2ea7c17b88e998a 214 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 2 200 1.1E-51 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWM22_RS07315 105489699a86ce4af2ea7c17b88e998a 214 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 6 202 19.264 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWM22_RS07315 105489699a86ce4af2ea7c17b88e998a 214 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 193 1.1E-49 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 SUPERFAMILY SSF55174 1 56 1.49E-12 T 28-03-2018 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 Pfam PF01479 S4 domain 1 43 2.0E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 228 1.2E-48 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 Gene3D G3DSA:3.30.70.580 59 144 1.3E-19 T 28-03-2018 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 Pfam PF00849 RNA pseudouridylate synthase 62 197 6.9E-23 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 Gene3D G3DSA:3.30.70.1560 145 209 3.1E-19 T 28-03-2018 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 SMART SM00363 1 65 2.0E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 Gene3D G3DSA:3.10.290.10 1 58 1.8E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS11745 b1f7852b0a447e74e1d942a49aa42f2d 242 SUPERFAMILY SSF55120 48 235 1.52E-42 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS05390 ffc258f048c47c224a97704e4d889252 266 Pfam PF01381 Helix-turn-helix 7 68 1.3E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS05390 ffc258f048c47c224a97704e4d889252 266 SUPERFAMILY SSF51306 146 263 7.98E-23 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWM22_RS05390 ffc258f048c47c224a97704e4d889252 266 Gene3D G3DSA:1.10.3100.10 1 149 8.8E-13 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS05390 ffc258f048c47c224a97704e4d889252 266 Gene3D G3DSA:2.10.109.10 151 265 5.2E-17 T 28-03-2018 CWM22_RS05390 ffc258f048c47c224a97704e4d889252 266 Pfam PF00717 Peptidase S24-like 187 248 1.7E-8 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWM22_RS05390 ffc258f048c47c224a97704e4d889252 266 SUPERFAMILY SSF47413 1 74 2.23E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS05390 ffc258f048c47c224a97704e4d889252 266 SMART SM00530 6 68 4.2E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 Pfam PF01979 Amidohydrolase family 51 420 1.4E-36 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 Gene3D G3DSA:3.20.20.140 60 413 4.6E-95 T 28-03-2018 CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 Gene3D G3DSA:2.30.40.10 1 59 2.1E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 ProSitePatterns PS00482 Dihydroorotase signature 1. 58 66 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 423 38.52 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 21 420 2.8E-109 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 SUPERFAMILY SSF51556 55 366 8.46E-96 T 28-03-2018 IPR032466 Metal-dependent hydrolase CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 SUPERFAMILY SSF51338 367 421 2.78E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWM22_RS05995 7a4bf6407954ee192c03150ffd6c88ea 423 SUPERFAMILY SSF51338 2 54 2.78E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 Pfam PF13538 UvrD-like helicase C-terminal domain 663 709 2.3E-17 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 Gene3D G3DSA:3.40.50.300 509 723 5.9E-30 T 28-03-2018 CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 6 734 2.9E-275 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 Gene3D G3DSA:3.40.50.300 327 508 6.1E-25 T 28-03-2018 CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 Pfam PF13604 AAA domain 332 531 3.6E-42 T 28-03-2018 CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 Pfam PF14490 Helix-hairpin-helix containing domain 148 237 1.4E-27 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 SUPERFAMILY SSF52540 451 516 7.59E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 SUPERFAMILY SSF52540 555 734 7.59E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 3 815 27.881 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 Gene3D G3DSA:1.10.150.20 94 149 1.6E-5 T 28-03-2018 CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 Gene3D G3DSA:1.10.150.20 157 210 0.35 T 28-03-2018 CWM22_RS01350 4dbdd70e54d5e2c3d8f42aa54c7a206d 830 SUPERFAMILY SSF52540 186 498 2.58E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 Gene3D G3DSA:3.40.50.150 1 161 1.3E-61 T 28-03-2018 CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 153 166 2.4E-19 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 2.4E-19 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 107 121 2.4E-19 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 Gene3D G3DSA:3.90.120.10 162 378 5.9E-26 T 28-03-2018 CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 68 80 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 SUPERFAMILY SSF53335 294 389 1.52E-87 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 SUPERFAMILY SSF53335 1 226 1.52E-87 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 387 1.0E-89 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 369 387 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CWM22_RS12900 01eac9241fe461c1a958e53208f07164 392 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 388 3.5E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS12390 30d1099464ae3955ce424f74aa4c761d 200 SUPERFAMILY SSF52218 1 171 6.04E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS12390 30d1099464ae3955ce424f74aa4c761d 200 Pfam PF03358 NADPH-dependent FMN reductase 1 145 6.4E-35 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWM22_RS12390 30d1099464ae3955ce424f74aa4c761d 200 Gene3D G3DSA:3.40.50.360 1 195 3.4E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS07925 22949f9a22421c3da8034ae465892511 224 SUPERFAMILY SSF158499 125 190 8.76E-20 T 28-03-2018 IPR006343 DnaD domain CWM22_RS07925 22949f9a22421c3da8034ae465892511 224 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 126 196 3.4E-28 T 28-03-2018 IPR006343 DnaD domain CWM22_RS07925 22949f9a22421c3da8034ae465892511 224 Pfam PF07261 Replication initiation and membrane attachment 127 197 2.8E-24 T 28-03-2018 IPR006343 DnaD domain CWM22_RS07925 22949f9a22421c3da8034ae465892511 224 Gene3D G3DSA:1.10.10.10 10 127 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07925 22949f9a22421c3da8034ae465892511 224 Gene3D G3DSA:1.10.10.630 128 196 3.5E-25 T 28-03-2018 IPR034829 DnaD-like domain CWM22_RS04020 88c989398d2faa4a014c050d4bed7575 131 SUPERFAMILY SSF159006 1 129 9.16E-27 T 28-03-2018 CWM22_RS04020 88c989398d2faa4a014c050d4bed7575 131 Gene3D G3DSA:2.30.30.290 52 131 2.3E-15 T 28-03-2018 IPR023385 YopX-like domain, beta barrel type CWM22_RS04020 88c989398d2faa4a014c050d4bed7575 131 Pfam PF09643 YopX protein 4 126 9.7E-20 T 28-03-2018 IPR019096 YopX protein CWM22_RS04020 88c989398d2faa4a014c050d4bed7575 131 Gene3D G3DSA:3.30.1490.160 16 51 9.2E-4 T 28-03-2018 CWM22_RS04020 88c989398d2faa4a014c050d4bed7575 131 TIGRFAM TIGR01671 phage_TIGR01671: phage conserved hypothetical protein TIGR01671 42 127 2.1E-13 T 28-03-2018 IPR010024 Conserved hypothetical protein CHP1671 CWM22_RS04020 88c989398d2faa4a014c050d4bed7575 131 Gene3D G3DSA:2.60.430.10 1 15 0.0058 T 28-03-2018 IPR024059 YopX-like domain, N-terminal CWM22_RS08310 ae9ca131d4ac8d7829f9ba8eb133fb98 87 SUPERFAMILY SSF55594 1 83 2.49E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWM22_RS08310 ae9ca131d4ac8d7829f9ba8eb133fb98 87 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.1E-25 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWM22_RS08310 ae9ca131d4ac8d7829f9ba8eb133fb98 87 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.1E-25 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWM22_RS08310 ae9ca131d4ac8d7829f9ba8eb133fb98 87 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.1E-25 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWM22_RS08310 ae9ca131d4ac8d7829f9ba8eb133fb98 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CWM22_RS08310 ae9ca131d4ac8d7829f9ba8eb133fb98 87 Gene3D G3DSA:3.30.1340.10 1 87 1.2E-31 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWM22_RS08310 ae9ca131d4ac8d7829f9ba8eb133fb98 87 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.1E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWM22_RS08310 ae9ca131d4ac8d7829f9ba8eb133fb98 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 2.3E-32 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWM22_RS08310 ae9ca131d4ac8d7829f9ba8eb133fb98 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CWM22_RS05525 51d46183ec2af38c74f5704fbcc15480 245 SMART SM00650 17 179 7.4E-59 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CWM22_RS05525 51d46183ec2af38c74f5704fbcc15480 245 Gene3D G3DSA:3.40.50.150 1 183 9.3E-36 T 28-03-2018 CWM22_RS05525 51d46183ec2af38c74f5704fbcc15480 245 Gene3D G3DSA:1.10.8.100 184 242 3.8E-31 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CWM22_RS05525 51d46183ec2af38c74f5704fbcc15480 245 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 60 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CWM22_RS05525 51d46183ec2af38c74f5704fbcc15480 245 SUPERFAMILY SSF53335 1 238 7.92E-53 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS05525 51d46183ec2af38c74f5704fbcc15480 245 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 239 2.5E-75 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CWM22_RS03850 98fd9629039ebd22a98422e144cbe2a0 220 Pfam PF10531 SLBB domain 76 130 2.5E-12 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWM22_RS03850 98fd9629039ebd22a98422e144cbe2a0 220 Pfam PF12836 Helix-hairpin-helix motif 155 218 3.0E-24 T 28-03-2018 CWM22_RS03850 98fd9629039ebd22a98422e144cbe2a0 220 SUPERFAMILY SSF47781 143 219 1.78E-29 T 28-03-2018 IPR010994 RuvA domain 2-like CWM22_RS03850 98fd9629039ebd22a98422e144cbe2a0 220 SMART SM00278 197 216 190.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWM22_RS03850 98fd9629039ebd22a98422e144cbe2a0 220 SMART SM00278 167 186 2.3 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWM22_RS03850 98fd9629039ebd22a98422e144cbe2a0 220 Gene3D G3DSA:3.10.560.10 57 168 1.5E-14 T 28-03-2018 CWM22_RS03850 98fd9629039ebd22a98422e144cbe2a0 220 Gene3D G3DSA:1.10.150.310 169 220 4.6E-18 T 28-03-2018 CWM22_RS03850 98fd9629039ebd22a98422e144cbe2a0 220 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 155 219 1.3E-20 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CWM22_RS03935 9c579b3992921f34aeccb4e349c55008 91 Gene3D G3DSA:1.10.10.10 36 89 8.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS00990 d64c18c13d0c5c47a07d61942aae6dc8 131 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 115 1.4E-32 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWM22_RS00990 d64c18c13d0c5c47a07d61942aae6dc8 131 SUPERFAMILY SSF50249 1 131 4.8E-39 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS00990 d64c18c13d0c5c47a07d61942aae6dc8 131 Gene3D G3DSA:2.40.50.140 1 110 5.0E-35 T 28-03-2018 CWM22_RS00990 d64c18c13d0c5c47a07d61942aae6dc8 131 Hamap MF_00984 Single-stranded DNA-binding protein. 2 106 31.061 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWM22_RS00990 d64c18c13d0c5c47a07d61942aae6dc8 131 PIRSF PIRSF002070 1 121 4.2E-32 T 28-03-2018 CWM22_RS00990 d64c18c13d0c5c47a07d61942aae6dc8 131 Pfam PF00436 Single-strand binding protein family 3 102 1.4E-29 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWM22_RS04620 c35c0bba871321d94c30d9bf342835fe 372 SUPERFAMILY SSF69322 56 218 4.45E-9 T 28-03-2018 CWM22_RS04620 c35c0bba871321d94c30d9bf342835fe 372 SUPERFAMILY SSF69322 272 372 4.45E-9 T 28-03-2018 CWM22_RS04620 c35c0bba871321d94c30d9bf342835fe 372 Gene3D G3DSA:2.130.10.10 58 372 7.8E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 Gene3D G3DSA:3.90.550.10 1 240 8.9E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 7.4E-174 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 Pfam PF12804 MobA-like NTP transferase domain 6 172 1.2E-19 T 28-03-2018 IPR025877 MobA-like NTP transferase CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 Gene3D G3DSA:2.160.10.10 241 348 1.9E-23 T 28-03-2018 CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.645 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 395 429 3.4E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 Gene3D G3DSA:2.160.10.10 349 446 9.3E-22 T 28-03-2018 CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 300 4.2E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 351 4.9E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 SUPERFAMILY SSF53448 4 253 8.45E-64 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 SUPERFAMILY SSF51161 257 445 1.6E-47 T 28-03-2018 IPR011004 Trimeric LpxA-like CWM22_RS03295 ae60821dd27f2428ad7af279a82ac708 460 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWM22_RS03445 e0ef6dde2649a76f2aa6b7da65df9f6b 71 Gene3D G3DSA:1.10.150.260 3 71 1.2E-22 T 28-03-2018 IPR023089 YozE SAM-like domain CWM22_RS03445 e0ef6dde2649a76f2aa6b7da65df9f6b 71 SUPERFAMILY SSF140652 2 71 1.31E-27 T 28-03-2018 IPR023089 YozE SAM-like domain CWM22_RS03445 e0ef6dde2649a76f2aa6b7da65df9f6b 71 PIRSF PIRSF037262 1 71 4.3E-29 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 CWM22_RS03445 e0ef6dde2649a76f2aa6b7da65df9f6b 71 Pfam PF06855 YozE SAM-like fold 4 69 2.9E-23 T 28-03-2018 IPR023089 YozE SAM-like domain CWM22_RS03445 e0ef6dde2649a76f2aa6b7da65df9f6b 71 Hamap MF_01538 UPF0346 protein . 1 71 21.959 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 CWM22_RS05430 4764aa48436bf52ff2d7f9c56a9010f2 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS05430 4764aa48436bf52ff2d7f9c56a9010f2 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS05430 4764aa48436bf52ff2d7f9c56a9010f2 450 Pfam PF03050 Transposase IS66 family 117 393 7.3E-83 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS00505 6e540f0434d6c2fbb3849ac93ffc6c7c 99 SUPERFAMILY SSF54189 1 91 6.83E-29 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00505 6e540f0434d6c2fbb3849ac93ffc6c7c 99 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00505 6e540f0434d6c2fbb3849ac93ffc6c7c 99 Pfam PF00276 Ribosomal protein L23 5 88 1.1E-29 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00505 6e540f0434d6c2fbb3849ac93ffc6c7c 99 Gene3D G3DSA:3.30.70.330 1 97 5.7E-31 T 28-03-2018 CWM22_RS00505 6e540f0434d6c2fbb3849ac93ffc6c7c 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 95 21.133 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 SUPERFAMILY SSF53187 324 403 1.71E-69 T 28-03-2018 CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 SUPERFAMILY SSF53187 4 212 1.71E-69 T 28-03-2018 CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 76 85 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 SUPERFAMILY SSF55031 211 322 2.72E-38 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 Hamap MF_00550 Peptidase T [pepT]. 3 406 55.923 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 Gene3D G3DSA:3.40.630.10 2 404 3.1E-41 T 28-03-2018 CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 PIRSF PIRSF037215 1 406 1.8E-178 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 Pfam PF07687 Peptidase dimerisation domain 209 305 5.0E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 403 3.5E-194 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CWM22_RS04960 55df066d4bbcaed954b8f22cb7b6f2e5 406 Pfam PF01546 Peptidase family M20/M25/M40 141 403 8.3E-10 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWM22_RS03610 9fc9a97c1bfa7f25b3e99606fbab2ae1 514 Gene3D G3DSA:3.90.1200.10 309 508 4.9E-25 T 28-03-2018 CWM22_RS03610 9fc9a97c1bfa7f25b3e99606fbab2ae1 514 Gene3D G3DSA:3.90.550.10 4 212 2.9E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS03610 9fc9a97c1bfa7f25b3e99606fbab2ae1 514 Gene3D G3DSA:3.30.200.20 213 298 7.3E-4 T 28-03-2018 CWM22_RS03610 9fc9a97c1bfa7f25b3e99606fbab2ae1 514 Pfam PF12804 MobA-like NTP transferase domain 6 109 1.8E-12 T 28-03-2018 IPR025877 MobA-like NTP transferase CWM22_RS03610 9fc9a97c1bfa7f25b3e99606fbab2ae1 514 SUPERFAMILY SSF56112 215 497 8.29E-38 T 28-03-2018 IPR011009 Protein kinase-like domain CWM22_RS03610 9fc9a97c1bfa7f25b3e99606fbab2ae1 514 SUPERFAMILY SSF53448 4 207 2.1E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS03610 9fc9a97c1bfa7f25b3e99606fbab2ae1 514 Pfam PF01633 Choline/ethanolamine kinase 254 438 3.4E-21 T 28-03-2018 CWM22_RS13200 8152f3e8c1b1660de60422a791dce051 450 PIRSF PIRSF034890 1 441 2.5E-86 T 28-03-2018 IPR012365 Phosphoesterase, lmo2642-related CWM22_RS13200 8152f3e8c1b1660de60422a791dce051 450 SUPERFAMILY SSF56300 40 331 2.64E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS13200 8152f3e8c1b1660de60422a791dce051 450 Pfam PF00149 Calcineurin-like phosphoesterase 40 283 3.9E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWM22_RS13200 8152f3e8c1b1660de60422a791dce051 450 Gene3D G3DSA:3.60.21.10 27 384 2.1E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 Gene3D G3DSA:1.10.10.650 2 108 1.3E-30 T 28-03-2018 IPR023319 Tex-like protein, HTH domain CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 Pfam PF16921 Tex protein YqgF-like domain 308 434 5.9E-53 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 Pfam PF00575 S1 RNA binding domain 633 711 7.6E-12 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 SMART SM00732 308 407 1.8E-37 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 Gene3D G3DSA:2.40.50.140 624 715 5.2E-19 T 28-03-2018 CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 SUPERFAMILY SSF158832 5 302 1.7E-98 T 28-03-2018 CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 SUPERFAMILY SSF47781 544 615 6.23E-17 T 28-03-2018 IPR010994 RuvA domain 2-like CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 Gene3D G3DSA:3.30.420.140 309 453 1.2E-53 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 Pfam PF09371 Tex-like protein N-terminal domain 8 188 8.3E-61 T 28-03-2018 IPR018974 Tex-like protein, N-terminal CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 Gene3D G3DSA:1.10.3500.10 109 308 4.3E-47 T 28-03-2018 IPR023323 Tex-like domain CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 Pfam PF12836 Helix-hairpin-helix motif 474 538 3.0E-27 T 28-03-2018 CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 SUPERFAMILY SSF50249 619 713 1.12E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 SMART SM00316 632 712 4.2E-18 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 SUPERFAMILY SSF47781 453 541 1.63E-26 T 28-03-2018 IPR010994 RuvA domain 2-like CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 SUPERFAMILY SSF53098 304 452 5.31E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS03145 690f61d229e50210baef0ed922de12c7 718 Gene3D G3DSA:1.10.150.310 482 613 1.9E-44 T 28-03-2018 CWM22_RS02475 2c785b44c3611afe6c20256fddb8e03c 104 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 62 14.132 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS02475 2c785b44c3611afe6c20256fddb8e03c 104 SUPERFAMILY SSF63562 2 77 9.07E-23 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWM22_RS02475 2c785b44c3611afe6c20256fddb8e03c 104 Gene3D G3DSA:3.90.940.10 2 100 1.5E-24 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWM22_RS02475 2c785b44c3611afe6c20256fddb8e03c 104 Pfam PF01192 RNA polymerase Rpb6 10 59 9.9E-10 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWM22_RS02475 2c785b44c3611afe6c20256fddb8e03c 104 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 2 59 1.2E-12 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS02475 2c785b44c3611afe6c20256fddb8e03c 104 SMART SM01409 9 61 1.2E-10 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.10 2375 2476 3.6E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.10 1492 1619 1.1E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.10 2248 2370 1.3E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.10 1098 1221 1.2E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.10 220 329 1.4E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.10 1740 1836 9.6E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.10 792 1083 3.2E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.10 2735 2836 3.6E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 SUPERFAMILY SSF49785 1861 1974 3.74E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.810 2837 2961 1.4E-10 T 28-03-2018 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.810 1222 1334 1.5E-11 T 28-03-2018 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.810 2962 3070 1.7E-16 T 28-03-2018 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.810 2477 2602 7.3E-11 T 28-03-2018 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.810 1620 1739 4.5E-12 T 28-03-2018 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.810 1987 2118 1.2E-9 T 28-03-2018 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.810 3071 3174 1.3E-13 T 28-03-2018 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.810 2124 2247 2.9E-13 T 28-03-2018 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.40.810 2603 2730 6.8E-14 T 28-03-2018 CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.120.260 1837 1978 6.8E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 SUPERFAMILY SSF49785 1355 1474 2.64E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Pfam PF00754 F5/8 type C domain 1858 1970 3.7E-10 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Pfam PF00754 F5/8 type C domain 1356 1460 3.2E-10 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CWM22_RS07700 1d53cce64f005bb207c0640c1b6d7720 3230 Gene3D G3DSA:2.60.120.260 1335 1474 6.3E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 SUPERFAMILY SSF54980 383 455 5.04E-16 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 159 9.0E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 Gene3D G3DSA:3.40.50.300 2 258 1.4E-40 T 28-03-2018 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 Pfam PF00009 Elongation factor Tu GTP binding domain 9 265 1.2E-50 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 PRINTS PR00315 GTP-binding elongation factor signature 12 25 3.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 PRINTS PR00315 GTP-binding elongation factor signature 82 92 3.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 PRINTS PR00315 GTP-binding elongation factor signature 134 143 3.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 PRINTS PR00315 GTP-binding elongation factor signature 98 109 3.1E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 Gene3D G3DSA:3.30.70.870 383 455 2.9E-12 T 28-03-2018 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 4 511 3.3E-197 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 514 49.643 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 SUPERFAMILY SSF50447 249 379 1.04E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 239 261 4.5E-9 T 28-03-2018 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 120 143 4.5E-9 T 28-03-2018 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 Pfam PF03144 Elongation factor Tu domain 2 303 369 3.7E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 Gene3D G3DSA:2.40.30.10 259 373 2.4E-19 T 28-03-2018 CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 SUPERFAMILY SSF52540 6 265 1.42E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08825 bc913896a1ef0701d72f0d0305987eea 514 Pfam PF16658 Class II release factor RF3, C-terminal domain 377 501 6.0E-43 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 Pfam PF00012 Hsp70 protein 4 73 1.1E-24 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 Pfam PF00012 Hsp70 protein 76 573 3.6E-217 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 Gene3D G3DSA:3.30.420.40 1 171 4.0E-66 T 28-03-2018 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 SUPERFAMILY SSF100920 354 510 1.44E-60 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 Gene3D G3DSA:1.20.1270.10 502 588 6.3E-17 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 607 36.151 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 Gene3D G3DSA:2.60.34.10 360 501 1.9E-64 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 SUPERFAMILY SSF100934 477 584 5.23E-11 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 PRINTS PR00301 70kDa heat shock protein signature 112 132 5.5E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 PRINTS PR00301 70kDa heat shock protein signature 304 320 5.5E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 PRINTS PR00301 70kDa heat shock protein signature 335 355 5.5E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.5E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 PRINTS PR00301 70kDa heat shock protein signature 358 377 5.5E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 PRINTS PR00301 70kDa heat shock protein signature 53 61 5.5E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 PRINTS PR00301 70kDa heat shock protein signature 172 182 5.5E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 PRINTS PR00301 70kDa heat shock protein signature 439 455 5.5E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.5E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 2.3E-282 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 SUPERFAMILY SSF53067 1 157 2.59E-56 T 28-03-2018 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 SUPERFAMILY SSF53067 160 351 2.35E-66 T 28-03-2018 CWM22_RS01890 a8dba3ed7925b632908eedf8d90be175 607 Gene3D G3DSA:3.30.420.40 172 336 2.6E-46 T 28-03-2018 CWM22_RS13365 926cd397ba326957247e35dd5c2f6d3d 364 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CWM22_RS13365 926cd397ba326957247e35dd5c2f6d3d 364 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 358 2.6E-16 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CWM22_RS13365 926cd397ba326957247e35dd5c2f6d3d 364 Gene3D G3DSA:3.40.50.300 1 363 5.7E-31 T 28-03-2018 CWM22_RS13365 926cd397ba326957247e35dd5c2f6d3d 364 ProSitePatterns PS00618 RecF protein signature 2. 305 323 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CWM22_RS13365 926cd397ba326957247e35dd5c2f6d3d 364 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 364 101.112 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CWM22_RS13365 926cd397ba326957247e35dd5c2f6d3d 364 SUPERFAMILY SSF52540 1 363 1.08E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13365 926cd397ba326957247e35dd5c2f6d3d 364 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 358 3.7E-125 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CWM22_RS02635 c36b1ccd9fdd98887ff22184771ac204 258 Hamap MF_01114 Regulatory protein RecX [recX]. 38 203 16.939 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CWM22_RS02635 c36b1ccd9fdd98887ff22184771ac204 258 Gene3D G3DSA:1.10.10.10 104 148 3.2E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02635 c36b1ccd9fdd98887ff22184771ac204 258 Gene3D G3DSA:1.10.10.10 39 103 7.7E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02635 c36b1ccd9fdd98887ff22184771ac204 258 Gene3D G3DSA:1.10.10.10 149 200 4.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02635 c36b1ccd9fdd98887ff22184771ac204 258 Gene3D G3DSA:1.10.10.10 210 258 1.6E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02635 c36b1ccd9fdd98887ff22184771ac204 258 Pfam PF02631 RecX family 80 198 2.1E-26 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CWM22_RS02635 c36b1ccd9fdd98887ff22184771ac204 258 Pfam PF02631 RecX family 203 255 5.8E-6 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 4.2E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 56 66 4.2E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 4.2E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 190 206 4.2E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 4.2E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 4.2E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 250 4.2E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 281 4.2E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 4.2E-67 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 1.6E-33 T 28-03-2018 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.6E-33 T 28-03-2018 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 1.6E-33 T 28-03-2018 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.6E-33 T 28-03-2018 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.6E-33 T 28-03-2018 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 Gene3D G3DSA:3.50.50.60 1 146 4.2E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 2 300 1.4E-110 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 Gene3D G3DSA:3.40.50.720 147 305 1.8E-23 T 28-03-2018 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 SUPERFAMILY SSF51905 1 299 6.24E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 130 150 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CWM22_RS10560 cebc6839f472b22d8ae12066884f9307 305 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 1.4E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS03805 b7c8adb4167b2d07bd8edb18b78cea26 238 SMART SM00363 1 64 6.7E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS03805 b7c8adb4167b2d07bd8edb18b78cea26 238 Gene3D G3DSA:3.10.290.10 1 72 4.4E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS03805 b7c8adb4167b2d07bd8edb18b78cea26 238 SUPERFAMILY SSF55174 1 56 8.83E-9 T 28-03-2018 CWM22_RS03805 b7c8adb4167b2d07bd8edb18b78cea26 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 6.8E-41 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWM22_RS03805 b7c8adb4167b2d07bd8edb18b78cea26 238 Pfam PF00849 RNA pseudouridylate synthase 62 195 1.3E-17 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS03805 b7c8adb4167b2d07bd8edb18b78cea26 238 Gene3D G3DSA:3.30.2350.10 73 235 2.4E-32 T 28-03-2018 CWM22_RS03805 b7c8adb4167b2d07bd8edb18b78cea26 238 Pfam PF01479 S4 domain 1 44 1.7E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS03805 b7c8adb4167b2d07bd8edb18b78cea26 238 SUPERFAMILY SSF55120 49 237 3.2E-40 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS03805 b7c8adb4167b2d07bd8edb18b78cea26 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 7 844 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Gene3D G3DSA:1.10.1420.10 249 394 1.9E-36 T 28-03-2018 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 676 692 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Pfam PF05190 MutS family domain IV 415 505 1.1E-27 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 SMART SM00533 270 578 6.3E-100 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Gene3D G3DSA:3.40.1170.10 1 129 1.3E-45 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 6 838 23.822 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Pfam PF00488 MutS domain V 598 785 7.0E-84 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 SUPERFAMILY SSF53150 123 265 1.57E-30 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Pfam PF01624 MutS domain I 8 118 4.0E-43 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Pfam PF05192 MutS domain III 255 546 8.4E-44 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Pfam PF05188 MutS domain II 126 239 6.9E-16 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 SUPERFAMILY SSF55271 4 114 3.01E-41 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Gene3D G3DSA:3.40.50.300 554 794 2.2E-45 T 28-03-2018 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 SUPERFAMILY SSF48334 253 551 3.92E-88 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 PIRSF PIRSF037677 1 198 3.0E-35 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 PIRSF PIRSF037677 181 804 2.9E-134 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Gene3D G3DSA:1.10.1420.10 395 522 6.3E-29 T 28-03-2018 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 SUPERFAMILY SSF52540 555 786 1.03E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 Gene3D G3DSA:3.30.420.110 130 248 1.8E-23 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CWM22_RS13055 ca2599496cc76d41d6ae3ec908d7ce70 846 SMART SM00534 595 782 1.8E-116 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Gene3D G3DSA:1.10.150.280 1337 1445 0.0064 T 28-03-2018 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Pfam PF14579 Helix-hairpin-helix motif 1376 1452 3.8E-6 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Pfam PF00929 Exonuclease 426 580 3.9E-31 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 234 1459 0.0 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 SUPERFAMILY SSF50249 237 316 1.76E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 SUPERFAMILY SSF53098 424 890 2.38E-91 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 SUPERFAMILY SSF89550 351 433 2.24E-5 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Pfam PF11490 DNA polymerase III polC-type N-terminus II 92 205 1.6E-22 T 28-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 420 639 6.9E-37 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Pfam PF14480 DNA polymerase III polC-type N-terminus I 4 78 2.7E-17 T 28-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Gene3D G3DSA:2.40.50.140 223 324 2.2E-19 T 28-03-2018 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 SMART SM00479 424 590 6.6E-44 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 840 1267 1.1E-89 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1463 421.64 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 SMART SM00481 339 406 1.0E-26 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Pfam PF02811 PHP domain 340 698 6.3E-48 T 28-03-2018 IPR004013 PHP domain GO:0003824 CWM22_RS11835 3ab48d0df806a26d3ae4dc6ee62e00d0 1463 Gene3D G3DSA:3.20.20.140 338 778 1.8E-51 T 28-03-2018 CWM22_RS07405 86705d9ec7dd54edade2f8cc1db053c5 759 Pfam PF13361 UvrD-like helicase C-terminal domain 276 616 3.2E-75 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWM22_RS07405 86705d9ec7dd54edade2f8cc1db053c5 759 Gene3D G3DSA:3.40.50.300 280 382 5.6E-29 T 28-03-2018 CWM22_RS07405 86705d9ec7dd54edade2f8cc1db053c5 759 Gene3D G3DSA:3.40.50.300 2 148 1.8E-25 T 28-03-2018 CWM22_RS07405 86705d9ec7dd54edade2f8cc1db053c5 759 Gene3D G3DSA:3.40.50.300 149 279 9.3E-35 T 28-03-2018 CWM22_RS07405 86705d9ec7dd54edade2f8cc1db053c5 759 SUPERFAMILY SSF52540 2 642 2.66E-175 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07405 86705d9ec7dd54edade2f8cc1db053c5 759 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 4 755 0.0 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CWM22_RS07405 86705d9ec7dd54edade2f8cc1db053c5 759 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 270 2.5E-80 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CWM22_RS07405 86705d9ec7dd54edade2f8cc1db053c5 759 Gene3D G3DSA:3.40.50.300 383 688 4.0E-50 T 28-03-2018 CWM22_RS09485 59a9c96ff90738c44517eb6b18e36adb 306 Pfam PF00701 Dihydrodipicolinate synthetase family 7 285 3.5E-58 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS09485 59a9c96ff90738c44517eb6b18e36adb 306 SMART SM01130 6 297 7.2E-66 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS09485 59a9c96ff90738c44517eb6b18e36adb 306 PIRSF PIRSF001365 2 305 4.7E-73 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS09485 59a9c96ff90738c44517eb6b18e36adb 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 6.9E-12 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS09485 59a9c96ff90738c44517eb6b18e36adb 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 134 151 6.9E-12 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS09485 59a9c96ff90738c44517eb6b18e36adb 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 6.9E-12 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS09485 59a9c96ff90738c44517eb6b18e36adb 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 6.9E-12 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS09485 59a9c96ff90738c44517eb6b18e36adb 306 SUPERFAMILY SSF51569 6 292 4.81E-71 T 28-03-2018 CWM22_RS09485 59a9c96ff90738c44517eb6b18e36adb 306 Gene3D G3DSA:3.20.20.70 1 304 9.5E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS11060 6660e3f800992d3ba84b394806d92a7c 314 SUPERFAMILY SSF144083 247 311 1.44E-14 T 28-03-2018 CWM22_RS11060 6660e3f800992d3ba84b394806d92a7c 314 Gene3D G3DSA:3.30.460.20 3 130 1.2E-19 T 28-03-2018 CWM22_RS11060 6660e3f800992d3ba84b394806d92a7c 314 Gene3D G3DSA:1.20.58.340 131 244 8.2E-13 T 28-03-2018 CWM22_RS11060 6660e3f800992d3ba84b394806d92a7c 314 Gene3D G3DSA:1.20.58.340 245 314 2.3E-13 T 28-03-2018 CWM22_RS11060 6660e3f800992d3ba84b394806d92a7c 314 Pfam PF01544 CorA-like Mg2+ transporter protein 22 310 2.5E-64 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWM22_RS11060 6660e3f800992d3ba84b394806d92a7c 314 SUPERFAMILY SSF143865 9 246 7.06E-48 T 28-03-2018 CWM22_RS01300 859138977a52bd33f6efffdbac9b1373 387 Pfam PF13936 Helix-turn-helix domain 2 45 1.5E-16 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CWM22_RS01300 859138977a52bd33f6efffdbac9b1373 387 Gene3D G3DSA:1.10.10.60 2 47 8.5E-10 T 28-03-2018 CWM22_RS01300 859138977a52bd33f6efffdbac9b1373 387 Gene3D G3DSA:3.30.420.10 202 363 7.0E-13 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS01300 859138977a52bd33f6efffdbac9b1373 387 SUPERFAMILY SSF53098 206 356 7.02E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS02805 859138977a52bd33f6efffdbac9b1373 387 Pfam PF13936 Helix-turn-helix domain 2 45 1.5E-16 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CWM22_RS02805 859138977a52bd33f6efffdbac9b1373 387 Gene3D G3DSA:1.10.10.60 2 47 8.5E-10 T 28-03-2018 CWM22_RS02805 859138977a52bd33f6efffdbac9b1373 387 Gene3D G3DSA:3.30.420.10 202 363 7.0E-13 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS02805 859138977a52bd33f6efffdbac9b1373 387 SUPERFAMILY SSF53098 206 356 7.02E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS12130 38ac09b08b3a54af315bbfd503012811 525 Gene3D G3DSA:3.40.50.300 298 524 1.0E-40 T 28-03-2018 CWM22_RS12130 38ac09b08b3a54af315bbfd503012811 525 SUPERFAMILY SSF52540 320 508 1.17E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12130 38ac09b08b3a54af315bbfd503012811 525 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS12130 38ac09b08b3a54af315bbfd503012811 525 Pfam PF00664 ABC transporter transmembrane region 8 275 1.6E-19 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS12130 38ac09b08b3a54af315bbfd503012811 525 SMART SM00382 341 525 6.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS12130 38ac09b08b3a54af315bbfd503012811 525 SUPERFAMILY SSF90123 3 285 7.59E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS12130 38ac09b08b3a54af315bbfd503012811 525 Gene3D G3DSA:1.20.1560.10 1 285 4.7E-29 T 28-03-2018 CWM22_RS12130 38ac09b08b3a54af315bbfd503012811 525 Pfam PF00005 ABC transporter 333 476 5.8E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 Gene3D G3DSA:2.60.120.260 350 482 2.1E-31 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 SUPERFAMILY SSF49785 446 580 7.51E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 Gene3D G3DSA:3.20.20.80 5 331 2.6E-76 T 28-03-2018 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 SUPERFAMILY SSF51445 6 331 2.45E-99 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 Pfam PF01301 Glycosyl hydrolases family 35 9 327 3.0E-114 T 28-03-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 PRINTS PR00742 Glycosyl hydrolase family 35 signature 89 108 1.2E-47 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 PRINTS PR00742 Glycosyl hydrolase family 35 signature 270 285 1.2E-47 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 PRINTS PR00742 Glycosyl hydrolase family 35 signature 13 30 1.2E-47 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 PRINTS PR00742 Glycosyl hydrolase family 35 signature 143 158 1.2E-47 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 PRINTS PR00742 Glycosyl hydrolase family 35 signature 235 250 1.2E-47 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 PRINTS PR00742 Glycosyl hydrolase family 35 signature 297 313 1.2E-47 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 PRINTS PR00742 Glycosyl hydrolase family 35 signature 34 52 1.2E-47 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 PRINTS PR00742 Glycosyl hydrolase family 35 signature 530 546 1.2E-47 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 PIRSF PIRSF006336 2 586 3.8E-173 T 28-03-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 CWM22_RS02660 9d930594ca729bf62acf37553f41caf2 590 Gene3D G3DSA:2.60.120.260 483 590 1.0E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS13275 914f32c4d8e07334825b8e3126060830 108 SUPERFAMILY SSF46785 9 105 5.46E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS13275 914f32c4d8e07334825b8e3126060830 108 Gene3D G3DSA:1.10.10.10 16 108 8.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS13275 914f32c4d8e07334825b8e3126060830 108 Pfam PF01638 HxlR-like helix-turn-helix 18 106 2.8E-34 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CWM22_RS11965 4c32773fd534e5284ca0d3ca9dfd6536 50 SUPERFAMILY SSF57829 4 50 2.99E-13 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWM22_RS11965 4c32773fd534e5284ca0d3ca9dfd6536 50 Pfam PF00471 Ribosomal protein L33 5 50 2.0E-15 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11965 4c32773fd534e5284ca0d3ca9dfd6536 50 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 50 4.3E-12 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11965 4c32773fd534e5284ca0d3ca9dfd6536 50 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 50 14.339 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11630 73f99bb881a998ba0c40f3b99c71f380 627 Gene3D G3DSA:1.20.120.670 405 623 1.3E-55 T 28-03-2018 CWM22_RS11630 73f99bb881a998ba0c40f3b99c71f380 627 SUPERFAMILY SSF51445 85 400 3.75E-43 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS11630 73f99bb881a998ba0c40f3b99c71f380 627 Gene3D G3DSA:3.20.20.80 83 402 1.3E-49 T 28-03-2018 CWM22_RS11630 73f99bb881a998ba0c40f3b99c71f380 627 Gene3D G3DSA:3.30.160.230 9 81 3.7E-20 T 28-03-2018 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Pfam PF07517 SecA DEAD-like domain 11 384 3.3E-120 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Gene3D G3DSA:3.90.1440.10 233 338 4.0E-37 T 28-03-2018 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Pfam PF07516 SecA Wing and Scaffold domain 572 780 8.4E-56 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 SUPERFAMILY SSF81886 818 830 4.97E-70 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 SUPERFAMILY SSF81886 574 791 4.97E-70 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 SUPERFAMILY SSF81767 232 350 1.96E-40 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Gene3D G3DSA:1.10.3060.10 700 792 9.0E-23 T 28-03-2018 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Gene3D G3DSA:1.10.3060.10 588 699 4.5E-28 T 28-03-2018 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 SMART SM00957 6 384 3.6E-261 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Gene3D G3DSA:3.40.50.300 36 232 6.7E-7 T 28-03-2018 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Pfam PF01043 SecA preprotein cross-linking domain 232 340 1.9E-33 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 SMART SM00958 228 340 2.0E-57 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Hamap MF_01382 Protein translocase subunit SecA [secA]. 1 783 18.991 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 SUPERFAMILY SSF52540 398 568 1.67E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 ProSitePatterns PS01312 SecA family signature. 482 497 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Gene3D G3DSA:3.40.50.300 339 398 2.0E-7 T 28-03-2018 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 29 498 8.4E-224 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Gene3D G3DSA:3.40.50.300 399 587 9.4E-52 T 28-03-2018 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 SUPERFAMILY SSF52540 350 397 5.43E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 SUPERFAMILY SSF52540 14 227 5.43E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 Pfam PF02810 SEC-C motif 822 840 9.5E-10 T 28-03-2018 IPR004027 SEC-C motif CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 PRINTS PR00906 SecA protein signature 100 114 4.4E-68 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 PRINTS PR00906 SecA protein signature 395 408 4.4E-68 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 PRINTS PR00906 SecA protein signature 169 189 4.4E-68 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 PRINTS PR00906 SecA protein signature 62 86 4.4E-68 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 PRINTS PR00906 SecA protein signature 321 343 4.4E-68 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 PRINTS PR00906 SecA protein signature 358 375 4.4E-68 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS10985 d305086741a4d294d15b820888cd2545 841 PRINTS PR00906 SecA protein signature 116 126 4.4E-68 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS09405 ef48452df402c62160955c489ccc7300 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 7.0E-68 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWM22_RS09405 ef48452df402c62160955c489ccc7300 155 Gene3D G3DSA:2.40.280.10 9 127 2.2E-50 T 28-03-2018 IPR023620 Small protein B CWM22_RS09405 ef48452df402c62160955c489ccc7300 155 Pfam PF01668 SmpB protein 9 150 2.9E-61 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWM22_RS09405 ef48452df402c62160955c489ccc7300 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 8 150 1.2E-57 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWM22_RS09405 ef48452df402c62160955c489ccc7300 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CWM22_RS09405 ef48452df402c62160955c489ccc7300 155 SUPERFAMILY SSF74982 4 132 6.15E-51 T 28-03-2018 IPR023620 Small protein B CWM22_RS09405 ef48452df402c62160955c489ccc7300 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 71.391 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 Gene3D G3DSA:2.60.40.810 462 640 1.5E-19 T 28-03-2018 CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 Gene3D G3DSA:2.60.40.810 27 226 1.3E-4 T 28-03-2018 CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 Pfam PF00746 LPXTG cell wall anchor motif 626 664 1.2E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 Pfam PF16569 Gram-positive pilin backbone subunit 2, Cna-B-like domain 231 347 9.5E-24 T 28-03-2018 IPR032334 Gram-positive pilin backbone subunit 2, Cna-B-like domain CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 Gene3D G3DSA:2.60.40.740 227 360 4.5E-22 T 28-03-2018 CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 634 663 3.7E-4 T 28-03-2018 CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 Pfam PF16570 Gram-positive pilin backbone subunit 3, Cna-B-like domain 369 497 6.0E-20 T 28-03-2018 IPR032332 Gram-positive pilin backbone subunit 3, Cna-B-like domain CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 211 344 4.8E-22 T 28-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 Pfam PF16555 Gram-positive pilin subunit D1, N-terminal 39 213 2.8E-39 T 28-03-2018 IPR032364 Gram-positive pilin subunit D1, N-terminal CWM22_RS07695 878f60b93654def566991c5a313ff5ca 668 Gene3D G3DSA:2.60.40.1140 361 456 9.7E-9 T 28-03-2018 CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 SMART SM00866 88 226 1.6E-24 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 8.1E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 8.1E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 SUPERFAMILY SSF64288 54 233 1.33E-35 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 SMART SM00345 7 66 6.9E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 1.5E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 3 233 1.3E-90 T 28-03-2018 IPR012770 Trehalose operon transcriptional repressor CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 SUPERFAMILY SSF46785 2 73 7.26E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 Gene3D G3DSA:1.10.10.10 1 67 9.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 Pfam PF07702 UTRA domain 91 226 9.1E-28 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS01405 ca93abcd8c34658bb31d788b52cf6718 237 Gene3D G3DSA:3.40.1410.10 72 236 1.0E-26 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Gene3D G3DSA:1.10.1790.10 299 400 2.2E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Pfam PF00874 PRD domain 209 284 4.7E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Pfam PF00874 PRD domain 308 396 8.2E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 SUPERFAMILY SSF52794 404 490 2.77E-9 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Gene3D G3DSA:1.10.1790.10 182 288 1.3E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Pfam PF05043 Mga helix-turn-helix domain 83 172 3.7E-15 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Gene3D G3DSA:1.10.10.10 1 69 8.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Gene3D G3DSA:3.40.50.2300 403 494 8.7E-21 T 28-03-2018 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Gene3D G3DSA:3.40.930.10 514 657 1.6E-12 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 SUPERFAMILY SSF63520 201 284 5.49E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 407 486 3.6E-7 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 SUPERFAMILY SSF55804 551 656 1.57E-16 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Pfam PF08279 HTH domain 13 63 2.5E-8 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 SUPERFAMILY SSF63520 293 399 4.84E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Gene3D G3DSA:1.10.10.10 94 160 1.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12575 7959a7777defa46a3bc056d456ea27d9 664 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 525 656 9.9E-13 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 15 49 2.6E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 TIGRFAM TIGR04308 repeat_SSSPR51: surface protein repeat SSSPR-51 2643 2692 8.7E-21 T 28-03-2018 IPR027579 Surface protein repeat SSSPR-51 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 TIGRFAM TIGR04308 repeat_SSSPR51: surface protein repeat SSSPR-51 2695 2744 8.7E-21 T 28-03-2018 IPR027579 Surface protein repeat SSSPR-51 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 TIGRFAM TIGR04308 repeat_SSSPR51: surface protein repeat SSSPR-51 2747 2795 6.7E-18 T 28-03-2018 IPR027579 Surface protein repeat SSSPR-51 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1877 1952 2.9E-7 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1705 1780 1.9E-6 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1193 1271 2.3E-6 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1013 1098 4.8E-7 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 2692 2747 0.0059 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1103 1187 1.8E-8 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 912 1009 1.8E-4 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 2221 2296 1.5E-6 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1547 1621 5.1E-5 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1275 1372 5.2E-6 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 2559 2632 6.5E-10 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 2049 2124 3.0E-8 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 812 908 0.0055 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1458 1542 4.8E-6 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 2744 2786 0.0092 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1378 1453 2.4E-4 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 1627 1701 6.2E-8 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 2393 2468 7.8E-8 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF06458 MucBP domain 2640 2695 0.0052 T 28-03-2018 IPR009459 MucBP domain CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2817 2849 1.1E-5 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1456 1544 7.2E-10 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 910 1010 1.6E-8 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1272 1374 6.5E-10 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 2552 2637 1.1E-14 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 804 909 2.4E-7 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1703 1841 1.2E-10 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 2698 2749 2.1E-7 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1190 1271 5.3E-11 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 2750 2813 3.1E-4 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1624 1702 6.5E-14 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 2638 2697 4.2E-8 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 2044 2191 6.6E-14 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 2388 2527 5.4E-13 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1109 1189 1.8E-13 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1545 1623 8.8E-12 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 2216 2364 7.8E-13 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1872 1993 2.2E-12 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1011 1108 1.2E-14 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Gene3D G3DSA:3.10.20.320 1375 1455 1.8E-9 T 28-03-2018 CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF00746 LPXTG cell wall anchor motif 2814 2850 2.3E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS07335 340ed63cee14c729cad432aee83cbc4f 2851 Pfam PF04650 YSIRK type signal peptide 15 35 3.4E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS05120 60e6e928c7e7c688f907c96c279b327d 511 Gene3D G3DSA:3.40.50.300 252 494 1.7E-37 T 28-03-2018 CWM22_RS05120 60e6e928c7e7c688f907c96c279b327d 511 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05120 60e6e928c7e7c688f907c96c279b327d 511 SMART SM00382 31 219 3.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05120 60e6e928c7e7c688f907c96c279b327d 511 SMART SM00382 284 474 18.0 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05120 60e6e928c7e7c688f907c96c279b327d 511 SUPERFAMILY SSF52540 257 489 7.36E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05120 60e6e928c7e7c688f907c96c279b327d 511 SUPERFAMILY SSF52540 5 229 1.85E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05120 60e6e928c7e7c688f907c96c279b327d 511 Pfam PF00005 ABC transporter 23 171 7.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05120 60e6e928c7e7c688f907c96c279b327d 511 Pfam PF00005 ABC transporter 276 431 1.3E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05120 60e6e928c7e7c688f907c96c279b327d 511 Gene3D G3DSA:3.40.50.300 3 248 7.1E-53 T 28-03-2018 CWM22_RS02380 901db09a14e4b9ddd13612d7c5b5c6c5 182 Hamap MF_01572 UPF0397 protein . 2 182 27.365 T 28-03-2018 IPR022914 Protein of unknown function UPF0397 CWM22_RS02380 901db09a14e4b9ddd13612d7c5b5c6c5 182 Pfam PF07155 ECF-type riboflavin transporter, S component 3 171 2.4E-50 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 12 650 90.1 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 Pfam PF00204 DNA gyrase B 232 401 1.4E-66 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR00418 DNA topoisomerase II family signature 79 92 8.6E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR00418 DNA topoisomerase II family signature 431 445 8.6E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR00418 DNA topoisomerase II family signature 583 599 8.6E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR00418 DNA topoisomerase II family signature 122 136 8.6E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR00418 DNA topoisomerase II family signature 279 292 8.6E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR00418 DNA topoisomerase II family signature 44 59 8.6E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR00418 DNA topoisomerase II family signature 535 547 8.6E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR00418 DNA topoisomerase II family signature 497 513 8.6E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR00418 DNA topoisomerase II family signature 515 532 8.6E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 Gene3D G3DSA:3.40.50.670 410 647 6.3E-100 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 Gene3D G3DSA:3.30.565.10 27 229 4.3E-74 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 SUPERFAMILY SSF54211 232 402 2.85E-63 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 ProSitePatterns PS00177 DNA topoisomerase II signature. 433 441 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 SUPERFAMILY SSF56719 405 642 5.49E-86 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 Gene3D G3DSA:3.30.230.10 231 403 1.9E-66 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 604 616 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 231 253 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 15 25 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 385 405 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 190 205 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 323 339 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 481 490 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 371 385 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 620 636 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 PRINTS PR01159 DNA gyrase subunit B signature 205 218 7.7E-76 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 15 648 1.2E-299 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 42 183 3.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 SUPERFAMILY SSF55874 14 227 1.15E-72 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 SMART SM00387 40 184 2.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 SMART SM00433 44 644 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 Pfam PF01751 Toprim domain 430 541 7.9E-18 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS04250 afd698777535f004b707660b6e7cdf66 650 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 579 640 6.4E-30 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 Gene3D G3DSA:3.40.50.1360 68 234 5.9E-35 T 28-03-2018 CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 SMART SM01134 66 228 1.8E-58 T 28-03-2018 CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 SUPERFAMILY SSF46785 2 56 1.26E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 SUPERFAMILY SSF100950 69 228 8.97E-34 T 28-03-2018 CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 Gene3D G3DSA:1.10.10.10 1 57 5.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 21 35 1.9E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 35 53 1.9E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 SMART SM00420 3 55 1.8E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 Pfam PF08220 DeoR-like helix-turn-helix domain 3 57 1.1E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 ProSitePatterns PS00894 DeoR-type HTH domain signature. 3 37 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CWM22_RS07530 d15789f1ee5b2dcce5d4a036ad5f1266 247 Pfam PF00455 DeoR C terminal sensor domain 69 227 1.2E-48 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 8 898 17.255 T 28-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 592 621 4.9E-53 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 133 146 4.9E-53 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 388 408 4.9E-53 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 727 753 4.9E-53 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 243 258 4.9E-53 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 550 570 4.9E-53 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 186 202 4.9E-53 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 Pfam PF00311 Phosphoenolpyruvate carboxylase 129 898 1.6E-255 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 SUPERFAMILY SSF51621 16 898 2.04E-286 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 Gene3D G3DSA:1.20.1440.90 273 390 4.8E-24 T 28-03-2018 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 134 145 - T 28-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS10020 c5127ee17d5235fdb6d2f31c5a1ec4d8 898 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 552 564 - T 28-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 Pfam PF00005 ABC transporter 335 467 5.9E-13 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 Pfam PF00005 ABC transporter 18 184 5.8E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 SUPERFAMILY SSF52540 293 514 2.44E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 SUPERFAMILY SSF52540 125 251 3.61E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 SUPERFAMILY SSF52540 2 92 3.61E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 Pfam PF12848 ABC transporter 224 304 1.2E-19 T 28-03-2018 IPR032781 ABC-transporter extension domain CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 Gene3D G3DSA:3.40.50.300 1 283 1.4E-56 T 28-03-2018 CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 Gene3D G3DSA:3.40.50.300 284 539 1.0E-38 T 28-03-2018 CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 SMART SM00382 344 512 0.82 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS13385 fe4e47a142919a5b35733b084dc075bc 540 SMART SM00382 26 228 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11255 bc22505e2bd1358912298cf37587cfcb 117 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 2.5E-30 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWM22_RS11255 bc22505e2bd1358912298cf37587cfcb 117 Gene3D G3DSA:3.30.300.20 4 117 3.2E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS11255 bc22505e2bd1358912298cf37587cfcb 117 SUPERFAMILY SSF89919 1 113 3.53E-30 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CWM22_RS11255 bc22505e2bd1358912298cf37587cfcb 117 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 117 21.721 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWM22_RS11255 bc22505e2bd1358912298cf37587cfcb 117 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 97 1.0E-45 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWM22_RS11255 bc22505e2bd1358912298cf37587cfcb 117 Pfam PF02033 Ribosome-binding factor A 6 110 1.0E-30 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWM22_RS11255 bc22505e2bd1358912298cf37587cfcb 117 ProSitePatterns PS01319 Ribosome-binding factor A signature. 76 97 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 258 26.8 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 214 236 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 PIRSF PIRSF000193 1 261 3.2E-79 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 SUPERFAMILY SSF48179 153 260 2.04E-36 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 SUPERFAMILY SSF51735 1 150 7.67E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 Gene3D G3DSA:3.40.50.720 1 151 4.4E-24 T 28-03-2018 CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 94 1.7E-14 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 Gene3D G3DSA:1.10.3730.10 152 261 2.1E-43 T 28-03-2018 CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 258 3.1E-79 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWM22_RS03505 91193bb22909469ac55841e6bdd9d9c4 261 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 154 258 2.0E-38 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CWM22_RS09075 7790714251590e1a21fed981b25b2dd6 115 Pfam PF04956 TrbC/VIRB2 family 18 106 2.1E-8 T 28-03-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 CWM22_RS03020 62300c0fae2f9cf2d8e45e0854c3e0d1 230 PIRSF PIRSF000709 172 226 11.0 T 28-03-2018 CWM22_RS03020 62300c0fae2f9cf2d8e45e0854c3e0d1 230 PIRSF PIRSF000709 3 114 1.7E-7 T 28-03-2018 CWM22_RS03020 62300c0fae2f9cf2d8e45e0854c3e0d1 230 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 43.189 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CWM22_RS03020 62300c0fae2f9cf2d8e45e0854c3e0d1 230 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 228 7.8E-107 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CWM22_RS03020 62300c0fae2f9cf2d8e45e0854c3e0d1 230 SUPERFAMILY SSF53254 1 227 7.07E-71 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS03020 62300c0fae2f9cf2d8e45e0854c3e0d1 230 Gene3D G3DSA:3.40.50.1240 1 230 3.9E-58 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS03020 62300c0fae2f9cf2d8e45e0854c3e0d1 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 123 1.2E-27 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS03020 62300c0fae2f9cf2d8e45e0854c3e0d1 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 128 218 2.6E-5 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS03020 62300c0fae2f9cf2d8e45e0854c3e0d1 230 SMART SM00855 3 189 2.1E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS01355 e4fbe04a842a67da19f4b8b8bfae37c7 209 ProSitePatterns PS00760 Signal peptidases I lysine active site. 87 99 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CWM22_RS01355 e4fbe04a842a67da19f4b8b8bfae37c7 209 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 21 203 2.8E-42 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWM22_RS01355 e4fbe04a842a67da19f4b8b8bfae37c7 209 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 35 51 6.1E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWM22_RS01355 e4fbe04a842a67da19f4b8b8bfae37c7 209 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 85 97 6.1E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWM22_RS01355 e4fbe04a842a67da19f4b8b8bfae37c7 209 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 162 181 6.1E-20 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWM22_RS01355 e4fbe04a842a67da19f4b8b8bfae37c7 209 SUPERFAMILY SSF51306 33 208 1.31E-49 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWM22_RS01355 e4fbe04a842a67da19f4b8b8bfae37c7 209 ProSitePatterns PS00501 Signal peptidases I serine active site. 44 51 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CWM22_RS01355 e4fbe04a842a67da19f4b8b8bfae37c7 209 Gene3D G3DSA:2.10.109.10 32 209 4.7E-36 T 28-03-2018 CWM22_RS01355 e4fbe04a842a67da19f4b8b8bfae37c7 209 Pfam PF00717 Peptidase S24-like 42 108 4.4E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWM22_RS04345 a789ee51b143fe7287c056ae752cd85c 333 Gene3D G3DSA:3.40.50.2300 161 299 3.1E-20 T 28-03-2018 CWM22_RS04345 a789ee51b143fe7287c056ae752cd85c 333 Gene3D G3DSA:3.40.50.2300 37 160 4.4E-20 T 28-03-2018 CWM22_RS04345 a789ee51b143fe7287c056ae752cd85c 333 Pfam PF04392 ABC transporter substrate binding protein 40 331 2.0E-108 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein CWM22_RS04345 a789ee51b143fe7287c056ae752cd85c 333 SUPERFAMILY SSF53822 37 257 9.79E-16 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 SUPERFAMILY SSF161098 522 723 2.49E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 SMART SM00079 28 248 5.1E-6 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 30 247 5.8E-57 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 279 496 5.8E-57 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 SUPERFAMILY SSF53850 1 248 3.88E-62 T 28-03-2018 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 521 625 1.2E-21 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 SUPERFAMILY SSF53850 277 496 2.12E-61 T 28-03-2018 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 Gene3D G3DSA:1.10.3720.10 521 731 1.1E-40 T 28-03-2018 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 SMART SM00062 27 249 2.7E-49 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 SMART SM00062 277 498 9.2E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 Gene3D G3DSA:3.40.190.10 149 275 5.6E-18 T 28-03-2018 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 Gene3D G3DSA:3.40.190.10 399 520 1.8E-18 T 28-03-2018 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 Gene3D G3DSA:3.40.190.10 22 148 2.4E-34 T 28-03-2018 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 Gene3D G3DSA:3.40.190.10 276 398 4.0E-35 T 28-03-2018 CWM22_RS05450 19cddc0b66305fda7aa7299a595a66d1 731 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 543 728 4.1E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 219 3.1E-21 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 36.166 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 18 311 1.9E-115 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 SUPERFAMILY SSF56553 48 169 2.88E-42 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 302 7.0E-27 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 Gene3D G3DSA:1.10.150.20 239 312 2.1E-24 T 28-03-2018 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 150 2.0E-23 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 SUPERFAMILY SSF55257 4 48 2.75E-29 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 SUPERFAMILY SSF55257 170 224 2.75E-29 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 251 296 1.0E-19 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 SMART SM00662 18 225 3.8E-90 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 SUPERFAMILY SSF47789 246 311 3.66E-23 T 28-03-2018 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 Gene3D G3DSA:3.30.1360.10 1 85 4.5E-20 T 28-03-2018 CWM22_RS00625 4204100727ab3897c3f996b7582634aa 312 Gene3D G3DSA:3.30.1360.10 105 222 3.9E-22 T 28-03-2018 CWM22_RS02535 f61eb8e976b9b14ad86aa9271ed83a9a 212 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 197 3.6E-61 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal CWM22_RS02535 f61eb8e976b9b14ad86aa9271ed83a9a 212 Gene3D G3DSA:3.30.70.240 136 199 1.4E-7 T 28-03-2018 CWM22_RS02535 f61eb8e976b9b14ad86aa9271ed83a9a 212 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 1.6E-32 T 28-03-2018 IPR001498 Impact, N-terminal CWM22_RS02535 f61eb8e976b9b14ad86aa9271ed83a9a 212 Gene3D G3DSA:3.30.230.30 5 134 3.4E-46 T 28-03-2018 IPR001498 Impact, N-terminal CWM22_RS02535 f61eb8e976b9b14ad86aa9271ed83a9a 212 SUPERFAMILY SSF54980 140 201 2.73E-5 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS02535 f61eb8e976b9b14ad86aa9271ed83a9a 212 Pfam PF09186 Domain of unknown function (DUF1949) 141 196 2.6E-6 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CWM22_RS02535 f61eb8e976b9b14ad86aa9271ed83a9a 212 SUPERFAMILY SSF54211 4 132 6.45E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS02535 f61eb8e976b9b14ad86aa9271ed83a9a 212 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 80 109 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CWM22_RS00325 66157d043aa9c458a4a27381b79d28d7 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 155 1.3E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWM22_RS00325 66157d043aa9c458a4a27381b79d28d7 162 SUPERFAMILY SSF52255 5 156 7.46E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWM22_RS00325 66157d043aa9c458a4a27381b79d28d7 162 Pfam PF00731 AIR carboxylase 5 151 1.6E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWM22_RS00325 66157d043aa9c458a4a27381b79d28d7 162 PIRSF PIRSF001338 1 162 2.7E-69 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CWM22_RS00325 66157d043aa9c458a4a27381b79d28d7 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 32.417 T 28-03-2018 IPR033747 Class I PurE CWM22_RS00325 66157d043aa9c458a4a27381b79d28d7 162 Gene3D G3DSA:3.40.50.7700 2 162 9.5E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWM22_RS00325 66157d043aa9c458a4a27381b79d28d7 162 SMART SM01001 3 154 3.2E-99 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWM22_RS11445 9cde493fbb95370c735716cb9c387ad3 340 Gene3D G3DSA:3.40.50.720 1 65 1.3E-4 T 28-03-2018 CWM22_RS11445 9cde493fbb95370c735716cb9c387ad3 340 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 178 1.3E-74 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWM22_RS11445 9cde493fbb95370c735716cb9c387ad3 340 PIRSF PIRSF000116 2 325 1.5E-52 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWM22_RS11445 9cde493fbb95370c735716cb9c387ad3 340 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 326 1.3E-63 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWM22_RS11445 9cde493fbb95370c735716cb9c387ad3 340 SUPERFAMILY SSF51735 5 183 1.19E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS11445 9cde493fbb95370c735716cb9c387ad3 340 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 327 1.6E-133 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWM22_RS11445 9cde493fbb95370c735716cb9c387ad3 340 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 329 43.84 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWM22_RS11445 9cde493fbb95370c735716cb9c387ad3 340 Gene3D G3DSA:1.10.1040.10 66 331 2.2E-112 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWM22_RS11445 9cde493fbb95370c735716cb9c387ad3 340 SUPERFAMILY SSF48179 184 330 1.6E-66 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWM22_RS07655 247161432875fa8b9cf8e579650a4994 324 Pfam PF04392 ABC transporter substrate binding protein 38 319 1.8E-84 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein CWM22_RS07655 247161432875fa8b9cf8e579650a4994 324 SUPERFAMILY SSF53822 44 301 1.76E-16 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS07655 247161432875fa8b9cf8e579650a4994 324 Gene3D G3DSA:3.40.50.2300 160 295 2.0E-23 T 28-03-2018 CWM22_RS07655 247161432875fa8b9cf8e579650a4994 324 Gene3D G3DSA:3.40.50.2300 35 159 5.1E-19 T 28-03-2018 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Gene3D G3DSA:1.10.10.10 1 70 1.0E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Gene3D G3DSA:1.10.10.10 90 156 2.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Pfam PF00874 PRD domain 311 395 7.1E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Pfam PF00874 PRD domain 208 286 4.5E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Pfam PF05043 Mga helix-turn-helix domain 98 170 1.3E-14 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Gene3D G3DSA:1.10.1790.10 166 289 1.1E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 SUPERFAMILY SSF46894 2 68 6.8E-6 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Gene3D G3DSA:3.40.930.10 512 657 2.7E-15 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 SUPERFAMILY SSF63520 306 400 2.49E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Gene3D G3DSA:3.40.50.2300 403 493 1.3E-19 T 28-03-2018 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 SUPERFAMILY SSF52794 406 491 8.89E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 SUPERFAMILY SSF55804 515 655 1.08E-15 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Pfam PF08279 HTH domain 7 66 1.0E-8 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 518 653 7.4E-12 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 SUPERFAMILY SSF46785 93 156 6.52E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 407 488 2.7E-6 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 SUPERFAMILY SSF63520 205 286 1.24E-13 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11125 3da2b0f88e613d0716acd37f444293b0 657 Gene3D G3DSA:1.10.1790.10 296 400 3.3E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS04555 8e36f707fb3dd80b07965192d67a6b22 447 Gene3D G3DSA:3.40.1190.10 45 304 1.1E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS04555 8e36f707fb3dd80b07965192d67a6b22 447 Pfam PF08353 Domain of unknown function (DUF1727) 319 429 2.6E-31 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 CWM22_RS04555 8e36f707fb3dd80b07965192d67a6b22 447 Pfam PF08245 Mur ligase middle domain 53 281 1.2E-13 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS04555 8e36f707fb3dd80b07965192d67a6b22 447 SUPERFAMILY SSF53623 40 192 3.09E-34 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS04555 8e36f707fb3dd80b07965192d67a6b22 447 SUPERFAMILY SSF53623 224 296 3.09E-34 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS02250 3d7ba43b795ff5ffbc12e8c1fa0925d9 195 SMART SM00471 21 148 2.3E-7 T 28-03-2018 IPR003607 HD/PDEase domain CWM22_RS02250 3d7ba43b795ff5ffbc12e8c1fa0925d9 195 TIGRFAM TIGR00277 HDIG: HDIG domain 26 116 3.4E-10 T 28-03-2018 IPR006675 HDIG domain CWM22_RS02250 3d7ba43b795ff5ffbc12e8c1fa0925d9 195 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 20 187 3.5E-50 T 28-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CWM22_RS02250 3d7ba43b795ff5ffbc12e8c1fa0925d9 195 SUPERFAMILY SSF109604 14 193 7.85E-36 T 28-03-2018 CWM22_RS02250 3d7ba43b795ff5ffbc12e8c1fa0925d9 195 Gene3D G3DSA:1.10.3210.10 6 192 5.9E-29 T 28-03-2018 CWM22_RS02250 3d7ba43b795ff5ffbc12e8c1fa0925d9 195 Pfam PF01966 HD domain 25 137 1.3E-14 T 28-03-2018 IPR006674 HD domain CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 SMART SM00895 93 215 1.1E-21 T 28-03-2018 IPR011711 GntR, C-terminal CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 SUPERFAMILY SSF46785 3 72 2.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 SUPERFAMILY SSF48008 92 221 3.14E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 SMART SM00345 9 68 6.8E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 1.7E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 Gene3D G3DSA:1.10.10.10 1 70 2.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 Gene3D G3DSA:1.20.120.530 88 230 1.9E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWM22_RS08115 3f45260f9c23e3ed94f6a8f449094348 238 Pfam PF07729 FCD domain 93 213 8.9E-23 T 28-03-2018 IPR011711 GntR, C-terminal CWM22_RS10040 ceb37385938220a8325fffdc0eb52860 283 Pfam PF01183 Glycosyl hydrolases family 25 71 255 1.5E-14 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CWM22_RS10040 ceb37385938220a8325fffdc0eb52860 283 SUPERFAMILY SSF51445 69 266 2.53E-38 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS10040 ceb37385938220a8325fffdc0eb52860 283 Gene3D G3DSA:3.20.20.80 56 280 5.1E-44 T 28-03-2018 CWM22_RS08140 134895ed4ed79c8d8efffe601337e584 63 Pfam PF11772 DNA-directed RNA polymerase subunit beta 16 62 8.2E-18 T 28-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA CWM22_RS08140 134895ed4ed79c8d8efffe601337e584 63 ProDom PD053619 EPUA PRECURSOR SIGNAL PEPTIDE YFDG EXTRACELLULAR OB2955 BH3736 GBS0884 SMU.1524C 5 60 2.0E-13 T 28-03-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA CWM22_RS13315 7b054e7d816a275f2b571a1d7dc2e215 429 SUPERFAMILY SSF53098 98 395 4.55E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS13315 7b054e7d816a275f2b571a1d7dc2e215 429 Pfam PF01609 Transposase DDE domain 100 351 4.5E-28 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS13315 7b054e7d816a275f2b571a1d7dc2e215 429 Gene3D G3DSA:3.90.350.10 119 335 5.9E-25 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS03315 f41d8a6ebd4363bedc1ad0586168c388 282 SUPERFAMILY SSF53613 2 275 3.11E-44 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS03315 f41d8a6ebd4363bedc1ad0586168c388 282 Pfam PF08543 Phosphomethylpyrimidine kinase 80 255 4.2E-18 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CWM22_RS03315 f41d8a6ebd4363bedc1ad0586168c388 282 Gene3D G3DSA:3.40.1190.20 2 266 5.7E-27 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS03040 0c26b7eeb5a3717c47292de299053d36 328 ProSitePatterns PS00018 EF-hand calcium-binding domain. 208 220 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CWM22_RS03040 0c26b7eeb5a3717c47292de299053d36 328 SUPERFAMILY SSF55347 147 289 8.34E-15 T 28-03-2018 CWM22_RS03040 0c26b7eeb5a3717c47292de299053d36 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 116 3.3E-21 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CWM22_RS03040 0c26b7eeb5a3717c47292de299053d36 328 SUPERFAMILY SSF51735 2 140 8.6E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS03040 0c26b7eeb5a3717c47292de299053d36 328 Gene3D G3DSA:3.40.50.720 1 143 8.9E-27 T 28-03-2018 CWM22_RS03040 0c26b7eeb5a3717c47292de299053d36 328 Gene3D G3DSA:3.30.360.10 144 325 2.4E-20 T 28-03-2018 CWM22_RS04750 210e3ecce17d9048fba6c677209cbc7e 257 SUPERFAMILY SSF56784 3 252 2.01E-69 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS04750 210e3ecce17d9048fba6c677209cbc7e 257 Pfam PF13242 HAD-hyrolase-like 179 251 8.2E-20 T 28-03-2018 CWM22_RS04750 210e3ecce17d9048fba6c677209cbc7e 257 PIRSF PIRSF000915 104 253 5.4E-33 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CWM22_RS04750 210e3ecce17d9048fba6c677209cbc7e 257 PIRSF PIRSF000915 1 113 3.9E-18 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CWM22_RS04750 210e3ecce17d9048fba6c677209cbc7e 257 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 228 5.5E-39 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CWM22_RS04750 210e3ecce17d9048fba6c677209cbc7e 257 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 3 252 3.8E-119 T 28-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 CWM22_RS04750 210e3ecce17d9048fba6c677209cbc7e 257 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 1.6E-20 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CWM22_RS04750 210e3ecce17d9048fba6c677209cbc7e 257 Gene3D G3DSA:3.40.50.1000 73 179 1.4E-29 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 SUPERFAMILY SSF50249 66 135 4.65E-12 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 Pfam PF08206 Ribonuclease B OB domain 72 128 1.2E-16 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 65 705 4.1E-184 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 Pfam PF00575 S1 RNA binding domain 626 705 6.6E-14 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 705 3.4E-244 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 SUPERFAMILY SSF50249 213 625 2.79E-141 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 SMART SM00955 252 581 1.7E-171 T 28-03-2018 CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 SMART SM00316 626 707 1.7E-14 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 Hamap MF_01895 Ribonuclease R [rnr]. 18 707 55.469 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 Pfam PF00773 RNB domain 252 578 5.5E-116 T 28-03-2018 CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 SUPERFAMILY SSF50249 628 705 1.34E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 Gene3D G3DSA:2.40.50.140 625 708 4.9E-18 T 28-03-2018 CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 Gene3D G3DSA:2.40.50.140 64 139 7.8E-4 T 28-03-2018 CWM22_RS09410 efc86b469659f403385b583c960b2cdb 789 ProSitePatterns PS01175 Ribonuclease II family signature. 548 572 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site CWM22_RS08510 37f109e72b84211aaf802c5d45b2963f 282 SUPERFAMILY SSF63817 86 219 7.59E-32 T 28-03-2018 IPR023365 Sortase domain CWM22_RS08510 37f109e72b84211aaf802c5d45b2963f 282 Pfam PF04203 Sortase family 93 218 6.1E-20 T 28-03-2018 IPR005754 Sortase family CWM22_RS08510 37f109e72b84211aaf802c5d45b2963f 282 Gene3D G3DSA:2.40.260.10 23 237 1.1E-33 T 28-03-2018 IPR023365 Sortase domain CWM22_RS08510 37f109e72b84211aaf802c5d45b2963f 282 TIGRFAM TIGR01076 sortase_fam: sortase 91 219 3.2E-34 T 28-03-2018 IPR005754 Sortase family CWM22_RS11505 3815c2bb67914d82b838dcdcb6f8859f 263 Pfam PF13676 TIR domain 2 110 1.5E-20 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CWM22_RS11505 3815c2bb67914d82b838dcdcb6f8859f 263 Gene3D G3DSA:3.40.50.10140 1 130 4.7E-18 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CWM22_RS11505 3815c2bb67914d82b838dcdcb6f8859f 263 SUPERFAMILY SSF52200 2 116 4.45E-17 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CWM22_RS05665 dae885d8b1310898dc88fd338e007025 177 Gene3D G3DSA:3.40.50.300 10 177 9.1E-18 T 28-03-2018 CWM22_RS05665 dae885d8b1310898dc88fd338e007025 177 SUPERFAMILY SSF52540 19 171 2.32E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05665 dae885d8b1310898dc88fd338e007025 177 Pfam PF13614 AAA domain 19 93 9.4E-16 T 28-03-2018 IPR025669 AAA domain CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 SUPERFAMILY SSF46785 1 82 2.93E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 Gene3D G3DSA:1.10.10.10 1 92 5.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 Gene3D G3DSA:3.40.190.10 189 268 6.0E-4 T 28-03-2018 CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 Gene3D G3DSA:3.40.190.10 93 188 5.7E-7 T 28-03-2018 CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 Pfam PF03466 LysR substrate binding domain 120 298 3.5E-10 T 28-03-2018 IPR005119 LysR, substrate-binding CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 SUPERFAMILY SSF53850 88 296 5.97E-22 T 28-03-2018 CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.5E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS05955 f904dce105ec2a7f0e8f861aaea2b132 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS03650 c7efcde2a8f74cd41f406d721e576e31 149 SMART SM00347 34 134 2.4E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS03650 c7efcde2a8f74cd41f406d721e576e31 149 Pfam PF01047 MarR family 41 98 1.8E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS03650 c7efcde2a8f74cd41f406d721e576e31 149 SUPERFAMILY SSF46785 17 146 7.64E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03650 c7efcde2a8f74cd41f406d721e576e31 149 Gene3D G3DSA:1.10.10.10 10 117 6.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03650 c7efcde2a8f74cd41f406d721e576e31 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 6.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS03650 c7efcde2a8f74cd41f406d721e576e31 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 6.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS03650 c7efcde2a8f74cd41f406d721e576e31 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 6.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS03650 c7efcde2a8f74cd41f406d721e576e31 149 Gene3D G3DSA:1.10.287.100 118 147 3.2E-4 T 28-03-2018 CWM22_RS00400 b212f62ffd8487331de9b21e607c8a59 307 SMART SM00530 9 65 1.1E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS00400 b212f62ffd8487331de9b21e607c8a59 307 SUPERFAMILY SSF47413 2 68 1.27E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS00400 b212f62ffd8487331de9b21e607c8a59 307 Gene3D G3DSA:1.10.3100.10 1 168 6.8E-13 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS00400 b212f62ffd8487331de9b21e607c8a59 307 Pfam PF13560 Helix-turn-helix domain 5 60 3.1E-6 T 28-03-2018 CWM22_RS05980 62e7bf397c4d613c60b8c3397cd2a1fa 210 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 178 1.0E-45 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS05980 62e7bf397c4d613c60b8c3397cd2a1fa 210 Pfam PF00156 Phosphoribosyl transferase domain 46 188 1.4E-19 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWM22_RS05980 62e7bf397c4d613c60b8c3397cd2a1fa 210 SUPERFAMILY SSF53271 10 208 6.56E-53 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS05980 62e7bf397c4d613c60b8c3397cd2a1fa 210 Gene3D G3DSA:3.40.50.2020 2 210 6.5E-39 T 28-03-2018 CWM22_RS05980 62e7bf397c4d613c60b8c3397cd2a1fa 210 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 210 30.625 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 5 89 1.2E-29 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 SUPERFAMILY SSF46609 1 90 1.1E-33 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 163 170 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 195 2.5E-40 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 Gene3D G3DSA:1.10.287.990 20 89 4.7E-26 T 28-03-2018 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 PIRSF PIRSF000349 1 201 7.8E-79 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 6.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 PRINTS PR01703 Manganese superoxide dismutase signature 161 173 6.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 6.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 6.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 6.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS03870 ecae1339d694a0e34ca0da29a3a1b3ae 201 SUPERFAMILY SSF54719 92 199 1.96E-44 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 SUPERFAMILY SSF47323 653 833 7.66E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 Gene3D G3DSA:1.10.730.10 569 832 1.3E-55 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 Pfam PF08264 Anticodon-binding domain of tRNA 684 794 2.0E-18 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 Pfam PF09334 tRNA synthetases class I (M) 40 164 2.6E-16 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 832 22.458 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 SUPERFAMILY SSF52374 413 658 2.82E-136 T 28-03-2018 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 SUPERFAMILY SSF52374 3 226 2.82E-136 T 28-03-2018 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 53 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 7.9E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 7.9E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 486 504 7.9E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 7.9E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 7.9E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 525 547 7.9E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 558 568 7.9E-55 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 401 5.8E-66 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 609 636 5.7E-6 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 833 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 Gene3D G3DSA:3.40.50.620 380 568 2.2E-51 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 SUPERFAMILY SSF50677 226 412 1.15E-54 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CWM22_RS12595 4d1d8afc16b47517cd07f047569cc858 833 Gene3D G3DSA:3.40.50.620 1 326 4.0E-96 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS04895 48c610acace6f63b77218197f7fd663e 278 SMART SM00062 42 270 1.6E-68 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS04895 48c610acace6f63b77218197f7fd663e 278 Gene3D G3DSA:3.40.190.10 1 167 4.8E-35 T 28-03-2018 CWM22_RS04895 48c610acace6f63b77218197f7fd663e 278 SMART SM00079 42 269 0.0091 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CWM22_RS04895 48c610acace6f63b77218197f7fd663e 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 269 1.5E-60 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS04895 48c610acace6f63b77218197f7fd663e 278 Gene3D G3DSA:3.40.190.10 168 278 9.7E-15 T 28-03-2018 CWM22_RS04895 48c610acace6f63b77218197f7fd663e 278 SUPERFAMILY SSF53850 4 270 4.6E-65 T 28-03-2018 CWM22_RS12440 32d74c2b177343ec0df19fb079219a3c 180 PIRSF PIRSF006806 1 179 3.0E-38 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CWM22_RS12440 32d74c2b177343ec0df19fb079219a3c 180 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 174 7.7E-36 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CWM22_RS12440 32d74c2b177343ec0df19fb079219a3c 180 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 174 1.4E-42 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CWM22_RS12440 32d74c2b177343ec0df19fb079219a3c 180 SUPERFAMILY SSF100950 2 174 7.67E-41 T 28-03-2018 CWM22_RS12440 32d74c2b177343ec0df19fb079219a3c 180 Gene3D G3DSA:3.40.50.10420 1 180 1.9E-45 T 28-03-2018 CWM22_RS09905 5a07d96d333b548a518b7697300a7845 375 Pfam PF13484 4Fe-4S double cluster binding domain 184 246 1.8E-12 T 28-03-2018 CWM22_RS09905 5a07d96d333b548a518b7697300a7845 375 Gene3D G3DSA:3.30.70.20 32 191 0.002 T 28-03-2018 CWM22_RS09905 5a07d96d333b548a518b7697300a7845 375 SUPERFAMILY SSF46548 157 246 1.78E-12 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWM22_RS09905 5a07d96d333b548a518b7697300a7845 375 Gene3D G3DSA:3.30.70.20 192 297 5.8E-7 T 28-03-2018 CWM22_RS09905 5a07d96d333b548a518b7697300a7845 375 Gene3D G3DSA:1.25.40.150 298 371 0.0018 T 28-03-2018 CWM22_RS09905 5a07d96d333b548a518b7697300a7845 375 Pfam PF08331 Domain of unknown function (DUF1730) 54 131 1.9E-15 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CWM22_RS09905 5a07d96d333b548a518b7697300a7845 375 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 184 195 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWM22_RS09905 5a07d96d333b548a518b7697300a7845 375 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 7 336 3.5E-112 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 SUPERFAMILY SSF56112 8 277 1.48E-80 T 28-03-2018 IPR011009 Protein kinase-like domain CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 Pfam PF03793 PASTA domain 372 434 1.0E-13 T 28-03-2018 IPR005543 PASTA domain CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 Pfam PF03793 PASTA domain 440 501 8.7E-18 T 28-03-2018 IPR005543 PASTA domain CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 Pfam PF03793 PASTA domain 507 569 6.1E-15 T 28-03-2018 IPR005543 PASTA domain CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 Pfam PF03793 PASTA domain 574 638 1.2E-8 T 28-03-2018 IPR005543 PASTA domain CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 Gene3D G3DSA:3.30.200.20 1 80 3.0E-23 T 28-03-2018 CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 SMART SM00220 12 270 1.3E-65 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 SMART SM00740 436 501 3.7E-15 T 28-03-2018 IPR005543 PASTA domain CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 SMART SM00740 570 639 3.7E-8 T 28-03-2018 IPR005543 PASTA domain CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 SMART SM00740 368 435 9.4E-15 T 28-03-2018 IPR005543 PASTA domain CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 SMART SM00740 502 569 1.1E-16 T 28-03-2018 IPR005543 PASTA domain CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 Gene3D G3DSA:1.10.510.10 81 475 8.4E-53 T 28-03-2018 CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 42 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CWM22_RS02500 86f868adb56f56c691db3c0031a678c5 664 Pfam PF00069 Protein kinase domain 12 233 1.6E-53 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 SUPERFAMILY SSF50891 279 385 3.8E-56 T 28-03-2018 IPR029000 Cyclophilin-like domain CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 SUPERFAMILY SSF50891 413 463 3.8E-56 T 28-03-2018 IPR029000 Cyclophilin-like domain CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 Pfam PF08282 haloacid dehalogenase-like hydrolase 15 261 1.8E-52 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 14 261 2.5E-49 T 28-03-2018 IPR000150 Cof family GO:0016787 CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 Gene3D G3DSA:3.40.50.1000 1 269 5.6E-36 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 ProSitePatterns PS01229 Hypothetical cof family signature 2. 215 237 - T 28-03-2018 CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 14 234 7.6E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 325 337 6.6E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 367 382 6.6E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 299 314 6.6E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 Gene3D G3DSA:2.40.100.10 270 466 1.1E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 287 463 1.3E-45 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWM22_RS02520 3bccbd4ada326fd667382cfbbf68ea2b 466 SUPERFAMILY SSF56784 5 265 8.8E-61 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09510 24e36527a6ac40120f20b3231f3d6171 435 SUPERFAMILY SSF53850 18 434 1.85E-61 T 28-03-2018 CWM22_RS09510 24e36527a6ac40120f20b3231f3d6171 435 Pfam PF01547 Bacterial extracellular solute-binding protein 60 350 1.0E-25 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CWM22_RS09510 24e36527a6ac40120f20b3231f3d6171 435 Gene3D G3DSA:3.40.190.10 225 389 0.11 T 28-03-2018 CWM22_RS09510 24e36527a6ac40120f20b3231f3d6171 435 Gene3D G3DSA:3.40.190.10 24 208 8.4E-33 T 28-03-2018 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 Gene3D G3DSA:3.40.50.2300 67 166 3.0E-25 T 28-03-2018 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 2.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 2.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 Gene3D G3DSA:3.40.50.2300 167 328 6.4E-36 T 28-03-2018 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 28-03-2018 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 SUPERFAMILY SSF53822 63 318 1.43E-59 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 Gene3D G3DSA:1.10.10.60 1 21 0.0017 T 28-03-2018 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 Pfam PF13377 Periplasmic binding protein-like domain 169 326 2.9E-26 T 28-03-2018 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 1.1E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 SMART SM00354 6 76 2.4E-31 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 Gene3D G3DSA:1.10.260.40 22 66 2.6E-22 T 28-03-2018 CWM22_RS03345 32e53ec24279b32c1a40790b5e28026c 328 SUPERFAMILY SSF47413 6 64 9.65E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Gene3D G3DSA:3.40.50.200 149 640 7.4E-75 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1550 1582 7.7E-6 T 28-03-2018 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 PRINTS PR00723 Subtilisin serine protease family (S8) signature 565 581 2.4E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 PRINTS PR00723 Subtilisin serine protease family (S8) signature 164 183 2.4E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 PRINTS PR00723 Subtilisin serine protease family (S8) signature 235 248 2.4E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 566 576 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 SUPERFAMILY SSF46997 1329 1392 1.26E-8 T 28-03-2018 IPR009063 Immunoglobulin/albumin-binding domain GO:0009405 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 SUPERFAMILY SSF52025 383 506 3.92E-19 T 28-03-2018 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Pfam PF06280 Fn3-like domain 652 762 1.1E-22 T 28-03-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Pfam PF04650 YSIRK type signal peptide 2 27 1.6E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 239 249 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 169 180 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Pfam PF07554 FIVAR domain 1327 1392 1.5E-7 T 28-03-2018 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Pfam PF07554 FIVAR domain 1258 1321 1.1E-4 T 28-03-2018 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Pfam PF07554 FIVAR domain 1401 1466 4.5E-9 T 28-03-2018 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Gene3D G3DSA:1.20.5.420 1254 1321 4.9E-11 T 28-03-2018 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Gene3D G3DSA:1.20.5.420 1396 1466 2.8E-12 T 28-03-2018 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Gene3D G3DSA:1.20.5.420 1324 1393 4.3E-10 T 28-03-2018 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Gene3D G3DSA:2.60.40.10 971 1074 1.0E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 SUPERFAMILY SSF46997 1415 1465 5.75E-7 T 28-03-2018 IPR009063 Immunoglobulin/albumin-binding domain GO:0009405 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 SUPERFAMILY SSF46997 1258 1320 3.56E-6 T 28-03-2018 IPR009063 Immunoglobulin/albumin-binding domain GO:0009405 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Gene3D G3DSA:2.60.40.1710 642 771 3.6E-28 T 28-03-2018 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Pfam PF02225 PA domain 422 503 9.2E-15 T 28-03-2018 IPR003137 PA domain CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Pfam PF00746 LPXTG cell wall anchor motif 1544 1584 2.5E-9 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 SUPERFAMILY SSF52743 151 379 1.3E-61 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 SUPERFAMILY SSF52743 525 637 1.3E-61 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 2 36 2.4E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS07070 ea5673ee207d7ca178c2c5b69a535baa 1585 Pfam PF00082 Subtilase family 164 629 1.3E-51 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 Gene3D G3DSA:3.40.1190.20 43 310 1.3E-44 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 308 5.4E-88 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 Hamap MF_01557 Tagatose-6-phosphate kinase [lacC]. 1 310 57.123 T 28-03-2018 IPR005926 Tagatose-6-phosphate kinase GO:0009024|GO:0019512 KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 PIRSF PIRSF000535 1 310 9.3E-130 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 TIGRFAM TIGR01231 lacC: tagatose-6-phosphate kinase 1 310 4.1E-152 T 28-03-2018 IPR005926 Tagatose-6-phosphate kinase GO:0009024|GO:0019512 KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 Gene3D G3DSA:2.20.150.10 9 42 2.6E-14 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 248 261 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 SUPERFAMILY SSF53613 1 291 3.12E-69 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 308 1.2E-100 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWM22_RS01630 4646a59266a1bf779cce8cb56666f9de 310 Pfam PF00294 pfkB family carbohydrate kinase 8 292 1.3E-59 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWM22_RS04545 4151d07f16170a8f30db386317c352fe 275 Gene3D G3DSA:3.40.50.150 12 268 4.0E-35 T 28-03-2018 CWM22_RS04545 4151d07f16170a8f30db386317c352fe 275 Pfam PF13649 Methyltransferase domain 94 178 8.1E-13 T 28-03-2018 CWM22_RS04545 4151d07f16170a8f30db386317c352fe 275 SUPERFAMILY SSF53335 16 208 7.21E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS04545 4151d07f16170a8f30db386317c352fe 275 PIRSF PIRSF018249 1 275 7.6E-85 T 28-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 CWM22_RS07320 b946d30f20ab78b28ff41f5c85b9133c 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS07320 b946d30f20ab78b28ff41f5c85b9133c 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 234 301 2.0E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS04900 b946d30f20ab78b28ff41f5c85b9133c 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS04900 b946d30f20ab78b28ff41f5c85b9133c 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 234 301 2.0E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS10800 b946d30f20ab78b28ff41f5c85b9133c 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS10800 b946d30f20ab78b28ff41f5c85b9133c 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 234 301 2.0E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS02365 b946d30f20ab78b28ff41f5c85b9133c 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS02365 b946d30f20ab78b28ff41f5c85b9133c 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 234 301 2.0E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS10810 d13cc3189b5719dfd64916e4aca7fe5e 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 266 7.6E-59 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10810 d13cc3189b5719dfd64916e4aca7fe5e 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 264 1.9E-49 T 28-03-2018 IPR000150 Cof family GO:0016787 CWM22_RS10810 d13cc3189b5719dfd64916e4aca7fe5e 271 SUPERFAMILY SSF56784 1 270 8.05E-63 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10810 d13cc3189b5719dfd64916e4aca7fe5e 271 Gene3D G3DSA:3.40.50.1000 19 271 2.4E-33 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10810 d13cc3189b5719dfd64916e4aca7fe5e 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 238 3.8E-29 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWM22_RS10810 d13cc3189b5719dfd64916e4aca7fe5e 271 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 CWM22_RS10810 d13cc3189b5719dfd64916e4aca7fe5e 271 Gene3D G3DSA:3.40.50.1000 1 18 0.05 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10615 fe34753de09ef63fd99e875e7f1c21ec 62 Gene3D G3DSA:1.10.10.60 1 25 3.8E-10 T 28-03-2018 CWM22_RS10615 fe34753de09ef63fd99e875e7f1c21ec 62 SMART SM00530 3 58 8.8E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS10615 fe34753de09ef63fd99e875e7f1c21ec 62 Gene3D G3DSA:3.30.1190.10 26 62 5.9E-12 T 28-03-2018 CWM22_RS10615 fe34753de09ef63fd99e875e7f1c21ec 62 Pfam PF01381 Helix-turn-helix 4 56 1.6E-18 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS10615 fe34753de09ef63fd99e875e7f1c21ec 62 SUPERFAMILY SSF47413 2 60 3.75E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS07100 70e5c8a334f213728f0fc6bc658f287c 256 SUPERFAMILY SSF161098 4 249 6.92E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS07100 70e5c8a334f213728f0fc6bc658f287c 256 Gene3D G3DSA:1.10.3720.10 2 251 1.6E-32 T 28-03-2018 CWM22_RS07100 70e5c8a334f213728f0fc6bc658f287c 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 244 1.6E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 SMART SM01260 29 405 5.7E-17 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01952 Nisin biosynthesis protein NisC signature 391 412 2.0E-27 T 28-03-2018 IPR020468 Nisin biosynthesis protein, NisC CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01952 Nisin biosynthesis protein NisC signature 153 177 2.0E-27 T 28-03-2018 IPR020468 Nisin biosynthesis protein, NisC CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01952 Nisin biosynthesis protein NisC signature 98 116 2.0E-27 T 28-03-2018 IPR020468 Nisin biosynthesis protein, NisC CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01952 Nisin biosynthesis protein NisC signature 178 201 2.0E-27 T 28-03-2018 IPR020468 Nisin biosynthesis protein, NisC CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01952 Nisin biosynthesis protein NisC signature 249 272 2.0E-27 T 28-03-2018 IPR020468 Nisin biosynthesis protein, NisC CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01952 Nisin biosynthesis protein NisC signature 117 135 2.0E-27 T 28-03-2018 IPR020468 Nisin biosynthesis protein, NisC CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01952 Nisin biosynthesis protein NisC signature 298 321 2.0E-27 T 28-03-2018 IPR020468 Nisin biosynthesis protein, NisC CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01952 Nisin biosynthesis protein NisC signature 52 68 2.0E-27 T 28-03-2018 IPR020468 Nisin biosynthesis protein, NisC CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 SUPERFAMILY SSF158745 25 406 8.63E-65 T 28-03-2018 CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 Pfam PF05147 Lanthionine synthetase C-like protein 36 400 4.2E-58 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01950 LanC-like protein superfamily signature 321 334 4.8E-20 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01950 LanC-like protein superfamily signature 374 391 4.8E-20 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01950 LanC-like protein superfamily signature 136 151 4.8E-20 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01950 LanC-like protein superfamily signature 82 100 4.8E-20 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01950 LanC-like protein superfamily signature 274 294 4.8E-20 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CWM22_RS05880 7a123833decc20b33a8b02bea8dfe96f 413 PRINTS PR01950 LanC-like protein superfamily signature 203 219 4.8E-20 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CWM22_RS09425 f29c7b28f39570d236dd1ccb4b8982dc 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 16.813 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS09425 f29c7b28f39570d236dd1ccb4b8982dc 49 SUPERFAMILY SSF57829 2 49 2.01E-16 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWM22_RS09425 f29c7b28f39570d236dd1ccb4b8982dc 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS09425 f29c7b28f39570d236dd1ccb4b8982dc 49 Pfam PF00471 Ribosomal protein L33 3 49 5.0E-19 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS09425 f29c7b28f39570d236dd1ccb4b8982dc 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 6.2E-19 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 Gene3D G3DSA:3.30.70.870 308 405 3.8E-32 T 28-03-2018 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 Gene3D G3DSA:3.40.50.300 71 199 3.0E-31 T 28-03-2018 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 149 1.1E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 603 3.3E-291 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 Gene3D G3DSA:2.40.50.250 488 578 3.5E-36 T 28-03-2018 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.9E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.9E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.9E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.9E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.9E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 SUPERFAMILY SSF54980 403 518 1.77E-29 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 Gene3D G3DSA:2.40.30.10 200 307 1.5E-21 T 28-03-2018 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 SUPERFAMILY SSF54980 307 392 6.12E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 Pfam PF00009 Elongation factor Tu GTP binding domain 7 200 2.9E-55 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 SUPERFAMILY SSF50447 155 304 5.89E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 Pfam PF03144 Elongation factor Tu domain 2 224 294 4.2E-13 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 SMART SM00838 400 485 5.1E-8 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 Gene3D G3DSA:3.30.70.240 406 487 4.7E-21 T 28-03-2018 CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 Pfam PF00679 Elongation factor G C-terminus 401 480 1.0E-24 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 SUPERFAMILY SSF52540 3 212 2.68E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02770 c01655b4eaadeece1b38a07d87b0769f 615 Gene3D G3DSA:3.40.50.300 2 70 8.3E-10 T 28-03-2018 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Gene3D G3DSA:1.20.1170.10 583 894 5.1E-7 T 28-03-2018 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 SMART SM00968 518 637 1.5E-39 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Pfam PF02463 RecF/RecN/SMC N terminal domain 730 1164 3.1E-29 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 242 9.2E-32 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 SUPERFAMILY SSF75553 479 680 1.57E-50 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Gene3D G3DSA:1.20.5.170 304 409 2.9E-4 T 28-03-2018 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Gene3D G3DSA:1.20.5.170 413 509 0.16 T 28-03-2018 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Gene3D G3DSA:3.40.50.300 943 1176 2.3E-31 T 28-03-2018 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Gene3D G3DSA:3.40.50.300 1 237 9.3E-43 T 28-03-2018 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1173 22.937 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 SUPERFAMILY SSF52540 1 207 2.7E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 SUPERFAMILY SSF52540 981 1173 2.7E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 636 2.9E-27 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 Gene3D G3DSA:1.20.5.340 238 303 8.6E-5 T 28-03-2018 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1171 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CWM22_RS08270 e1b9d2a26fced28df46384678e34f557 1177 PIRSF PIRSF005719 1 1177 1.5E-276 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 SUPERFAMILY SSF52794 170 268 1.33E-35 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 171 253 1.7E-29 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 284 648 5.9E-116 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 SUPERFAMILY SSF55804 1 147 7.19E-42 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 Pfam PF02378 Phosphotransferase system, EIIC 298 595 1.6E-24 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 Gene3D G3DSA:3.40.930.10 1 162 1.3E-41 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 4.8E-43 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 172 261 9.6E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 147 6.2E-35 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CWM22_RS06995 3ebbab540202723a9844e7cf18aa0710 651 Gene3D G3DSA:3.40.50.2300 169 265 5.6E-38 T 28-03-2018 CWM22_RS02110 46ea5376cb28f7207d541b17ed334b51 281 SUPERFAMILY SSF56784 2 276 2.71E-62 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS02110 46ea5376cb28f7207d541b17ed334b51 281 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 246 8.5E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWM22_RS02110 46ea5376cb28f7207d541b17ed334b51 281 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 273 3.3E-56 T 28-03-2018 IPR000150 Cof family GO:0016787 CWM22_RS02110 46ea5376cb28f7207d541b17ed334b51 281 Gene3D G3DSA:3.40.50.1000 2 278 6.4E-41 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS02110 46ea5376cb28f7207d541b17ed334b51 281 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 273 1.8E-64 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS02110 46ea5376cb28f7207d541b17ed334b51 281 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 CWM22_RS01450 7939a7972779c3628a38c8528bf157d8 104 ProSitePatterns PS00194 Thioredoxin family active site. 20 38 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CWM22_RS01450 7939a7972779c3628a38c8528bf157d8 104 SUPERFAMILY SSF52833 2 102 3.54E-36 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS01450 7939a7972779c3628a38c8528bf157d8 104 Pfam PF00085 Thioredoxin 2 101 9.5E-30 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWM22_RS01450 7939a7972779c3628a38c8528bf157d8 104 Gene3D G3DSA:3.40.30.10 1 104 4.7E-33 T 28-03-2018 CWM22_RS01450 7939a7972779c3628a38c8528bf157d8 104 PRINTS PR00421 Thioredoxin family signature 19 27 7.5E-8 T 28-03-2018 CWM22_RS01450 7939a7972779c3628a38c8528bf157d8 104 PRINTS PR00421 Thioredoxin family signature 68 79 7.5E-8 T 28-03-2018 CWM22_RS01450 7939a7972779c3628a38c8528bf157d8 104 PRINTS PR00421 Thioredoxin family signature 27 36 7.5E-8 T 28-03-2018 CWM22_RS01450 7939a7972779c3628a38c8528bf157d8 104 PIRSF PIRSF000077 1 103 1.4E-38 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CWM22_RS01450 7939a7972779c3628a38c8528bf157d8 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 101 1.0E-34 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CWM22_RS11085 d73abd414cbc16b99571c2ad701cb253 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 4 321 1.3E-100 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CWM22_RS11085 d73abd414cbc16b99571c2ad701cb253 329 Gene3D G3DSA:3.30.930.10 1 245 2.1E-71 T 28-03-2018 CWM22_RS11085 d73abd414cbc16b99571c2ad701cb253 329 Gene3D G3DSA:3.30.390.50 246 329 7.2E-21 T 28-03-2018 CWM22_RS11085 d73abd414cbc16b99571c2ad701cb253 329 SUPERFAMILY SSF55681 1 241 4.14E-76 T 28-03-2018 CWM22_RS11085 d73abd414cbc16b99571c2ad701cb253 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 46 154 1.6E-8 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWM22_RS11085 d73abd414cbc16b99571c2ad701cb253 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 243 326 5.2E-24 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CWM22_RS11085 d73abd414cbc16b99571c2ad701cb253 329 SUPERFAMILY SSF82649 242 328 1.99E-23 T 28-03-2018 CWM22_RS11310 f5f3e0c8c5038a7aa24fc0024328fb33 137 PRINTS PR00332 Histidine triad family signature 5 21 3.6E-18 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CWM22_RS11310 f5f3e0c8c5038a7aa24fc0024328fb33 137 PRINTS PR00332 Histidine triad family signature 93 103 3.6E-18 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CWM22_RS11310 f5f3e0c8c5038a7aa24fc0024328fb33 137 PRINTS PR00332 Histidine triad family signature 26 44 3.6E-18 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CWM22_RS11310 f5f3e0c8c5038a7aa24fc0024328fb33 137 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 28-03-2018 IPR019808 Histidine triad, conserved site CWM22_RS11310 f5f3e0c8c5038a7aa24fc0024328fb33 137 SUPERFAMILY SSF54197 1 111 4.95E-43 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CWM22_RS11310 f5f3e0c8c5038a7aa24fc0024328fb33 137 Pfam PF01230 HIT domain 12 107 9.2E-30 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CWM22_RS11310 f5f3e0c8c5038a7aa24fc0024328fb33 137 Gene3D G3DSA:3.30.428.10 1 130 1.1E-39 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CWM22_RS01255 f2feed01c545ac6723d849b9d127f071 315 Pfam PF00144 Beta-lactamase 9 298 1.6E-44 T 28-03-2018 IPR001466 Beta-lactamase-related CWM22_RS01255 f2feed01c545ac6723d849b9d127f071 315 Gene3D G3DSA:3.40.710.10 2 311 2.6E-48 T 28-03-2018 CWM22_RS01255 f2feed01c545ac6723d849b9d127f071 315 SUPERFAMILY SSF56601 3 296 1.15E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS12250 401bc3553d42b8f542d70a1e5bbf5f1a 315 Pfam PF02574 Homocysteine S-methyltransferase 14 311 9.3E-76 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CWM22_RS12250 401bc3553d42b8f542d70a1e5bbf5f1a 315 SUPERFAMILY SSF82282 2 314 1.44E-81 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CWM22_RS12250 401bc3553d42b8f542d70a1e5bbf5f1a 315 PIRSF PIRSF037505 273 314 8.9 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CWM22_RS12250 401bc3553d42b8f542d70a1e5bbf5f1a 315 PIRSF PIRSF037505 3 198 1.8E-7 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CWM22_RS12250 401bc3553d42b8f542d70a1e5bbf5f1a 315 Gene3D G3DSA:3.20.20.330 1 315 2.3E-97 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CWM22_RS05175 be93ac3b9c49f7fef119aab263e31e13 240 SUPERFAMILY SSF52540 54 232 3.93E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05175 be93ac3b9c49f7fef119aab263e31e13 240 Pfam PF13614 AAA domain 54 201 5.6E-14 T 28-03-2018 IPR025669 AAA domain CWM22_RS05175 be93ac3b9c49f7fef119aab263e31e13 240 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 35 237 4.7E-57 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CWM22_RS05175 be93ac3b9c49f7fef119aab263e31e13 240 Gene3D G3DSA:3.40.50.300 24 239 7.5E-39 T 28-03-2018 CWM22_RS05355 24dc1a522cd6110838f183528a65b779 272 SUPERFAMILY SSF111331 27 267 1.83E-58 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CWM22_RS05355 24dc1a522cd6110838f183528a65b779 272 Hamap MF_00361 NAD kinase [nadK]. 7 269 23.864 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CWM22_RS05355 24dc1a522cd6110838f183528a65b779 272 Gene3D G3DSA:2.60.200.30 128 248 1.8E-22 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CWM22_RS05355 24dc1a522cd6110838f183528a65b779 272 Gene3D G3DSA:3.40.50.10330 7 127 1.6E-21 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CWM22_RS05355 24dc1a522cd6110838f183528a65b779 272 Pfam PF01513 ATP-NAD kinase 40 227 5.5E-20 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 Gene3D G3DSA:1.10.287.130 233 302 5.0E-9 T 28-03-2018 CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 SUPERFAMILY SSF47384 234 305 2.94E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 SUPERFAMILY SSF55874 317 458 1.28E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 306 1.3E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 Gene3D G3DSA:3.30.565.10 313 459 1.1E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 SMART SM00387 349 459 1.2E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 4.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 4.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 4.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 4.1E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 SMART SM00388 239 306 6.9E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS05075 506c973f7fce116d4808723803b25d72 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 458 2.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS06025 abef993a39f20a2df6cf5e5a2289057b 335 Pfam PF02698 DUF218 domain 166 306 1.9E-33 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CWM22_RS06025 abef993a39f20a2df6cf5e5a2289057b 335 Gene3D G3DSA:3.40.50.620 156 293 3.2E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS10710 8422dc0307b6dfaab48ede72433526aa 85 Hamap MF_01103 UPF0291 protein . 1 59 16.713 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CWM22_RS10710 8422dc0307b6dfaab48ede72433526aa 85 SUPERFAMILY SSF158221 2 41 1.83E-13 T 28-03-2018 CWM22_RS10710 8422dc0307b6dfaab48ede72433526aa 85 Gene3D G3DSA:1.10.287.540 3 55 2.3E-25 T 28-03-2018 CWM22_RS10710 8422dc0307b6dfaab48ede72433526aa 85 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 67 1.9E-30 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CWM22_RS13140 530a85a459c2f16c739c60765d928b63 431 Gene3D G3DSA:1.20.58.370 23 156 4.1E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CWM22_RS13140 530a85a459c2f16c739c60765d928b63 431 Gene3D G3DSA:1.10.3720.10 180 424 9.6E-40 T 28-03-2018 CWM22_RS13140 530a85a459c2f16c739c60765d928b63 431 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 206 423 3.5E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS13140 530a85a459c2f16c739c60765d928b63 431 SUPERFAMILY SSF161098 173 416 4.19E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS13140 530a85a459c2f16c739c60765d928b63 431 SUPERFAMILY SSF160964 119 171 5.75E-9 T 28-03-2018 CWM22_RS13140 530a85a459c2f16c739c60765d928b63 431 SUPERFAMILY SSF160964 75 88 5.75E-9 T 28-03-2018 CWM22_RS01290 88b67c713597a42811d6070fbb0c819b 209 SUPERFAMILY SSF51735 1 206 2.44E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS01290 88b67c713597a42811d6070fbb0c819b 209 Gene3D G3DSA:3.40.50.720 1 204 3.0E-15 T 28-03-2018 CWM22_RS01290 88b67c713597a42811d6070fbb0c819b 209 Pfam PF13460 NAD(P)H-binding 8 195 9.3E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 523 538 1.2E-63 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 320 1.2E-63 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 268 1.2E-63 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 456 477 1.2E-63 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 176 1.2E-63 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 545 565 1.2E-63 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 427 1.2E-63 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 380 394 1.2E-63 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 151 1.2E-63 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 Gene3D G3DSA:3.50.50.60 125 285 4.4E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 Pfam PF00364 Biotin-requiring enzyme 4 76 1.1E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 274 8.8E-36 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 379 395 8.8E-36 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 405 427 8.8E-36 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 149 8.8E-36 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 313 8.8E-36 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 Gene3D G3DSA:3.90.1170.30 1 46 7.0E-12 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 Gene3D G3DSA:3.30.390.30 460 584 2.1E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 Gene3D G3DSA:3.40.50.720 286 458 2.2E-29 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 460 570 4.8E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 SUPERFAMILY SSF51230 1 94 5.37E-25 T 28-03-2018 IPR011053 Single hybrid motif CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 PIRSF PIRSF000350 70 571 3.1E-76 T 28-03-2018 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 SUPERFAMILY SSF55424 459 581 6.87E-40 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 128 440 3.5E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 SUPERFAMILY SSF51905 225 312 1.48E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 SUPERFAMILY SSF51905 126 178 1.48E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 SUPERFAMILY SSF51905 340 479 1.48E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 127 580 1.6E-156 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 162 172 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWM22_RS11185 29053afb8bd1d83d497bbc0ac6d3d6e3 586 Gene3D G3DSA:3.90.1170.30 47 110 0.019 T 28-03-2018 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 5.3E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 5.3E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 5.3E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 5.3E-36 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 SUPERFAMILY SSF81271 287 371 6.76E-36 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 371 1.3E-148 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 Pfam PF06071 Protein of unknown function (DUF933) 287 370 1.7E-40 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 371 43.694 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 Gene3D G3DSA:3.10.20.30 271 370 6.5E-46 T 28-03-2018 IPR012675 Beta-grasp domain CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 PIRSF PIRSF006641 1 371 2.5E-155 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 Gene3D G3DSA:1.10.150.300 123 205 7.4E-28 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 Gene3D G3DSA:3.40.50.300 1 80 1.4E-7 T 28-03-2018 CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 SUPERFAMILY SSF52540 3 309 4.47E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00030 6e2f13f5e71a9ca4666ff9c1ae7c95a1 371 Pfam PF01926 50S ribosome-binding GTPase 5 113 4.4E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS12145 3b57d8df7f2f0f38013059493ba70d1b 814 Gene3D G3DSA:3.40.720.10 462 761 9.8E-10 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWM22_RS12145 3b57d8df7f2f0f38013059493ba70d1b 814 SUPERFAMILY SSF53649 571 705 2.26E-6 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWM22_RS12145 3b57d8df7f2f0f38013059493ba70d1b 814 Pfam PF00884 Sulfatase 467 743 6.0E-28 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CWM22_RS00500 119c3cb1a54ce867c946d9c10d7471b3 207 SUPERFAMILY SSF52166 1 206 1.31E-76 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CWM22_RS00500 119c3cb1a54ce867c946d9c10d7471b3 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 35.684 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00500 119c3cb1a54ce867c946d9c10d7471b3 207 Gene3D G3DSA:3.40.1370.10 147 205 3.5E-13 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CWM22_RS00500 119c3cb1a54ce867c946d9c10d7471b3 207 Gene3D G3DSA:3.40.1370.10 2 146 6.1E-55 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CWM22_RS00500 119c3cb1a54ce867c946d9c10d7471b3 207 Pfam PF00573 Ribosomal protein L4/L1 family 18 204 1.7E-65 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CWM22_RS00500 119c3cb1a54ce867c946d9c10d7471b3 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 204 6.5E-77 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 Gene3D G3DSA:2.60.40.1180 631 724 2.3E-25 T 28-03-2018 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 PIRSF PIRSF005536 2 724 2.8E-268 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 30 283 8.8E-73 T 28-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 Gene3D G3DSA:3.20.20.70 308 630 1.7E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 SUPERFAMILY SSF51445 323 660 1.99E-105 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 646 721 1.3E-23 T 28-03-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 517 533 1.8E-59 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 328 342 1.8E-59 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 239 254 1.8E-59 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 406 428 1.8E-59 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 356 371 1.8E-59 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 464 479 1.8E-59 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 290 310 1.8E-59 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 PRINTS PR00743 Glycosyl hydrolase family 36 signature 542 558 1.8E-59 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 ProSitePatterns PS00512 Alpha-galactosidase signature. 357 372 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 Gene3D G3DSA:2.70.98.60 1 307 1.6E-83 T 28-03-2018 CWM22_RS08720 453adacfbc39b38615f3844e1645cefe 724 Pfam PF02065 Melibiase 288 633 1.1E-158 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 Gene3D G3DSA:2.40.128.20 316 502 1.2E-68 T 28-03-2018 IPR012674 Calycin CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00691 Adhesin B signature 29 50 2.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00691 Adhesin B signature 193 210 2.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00691 Adhesin B signature 73 92 2.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00691 Adhesin B signature 54 72 2.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00691 Adhesin B signature 286 304 2.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00691 Adhesin B signature 137 156 2.3E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 323 502 7.1E-83 T 28-03-2018 IPR015304 ZinT domain GO:0008270 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 Gene3D G3DSA:3.40.50.1980 29 187 4.4E-56 T 28-03-2018 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 SUPERFAMILY SSF53807 14 305 7.36E-85 T 28-03-2018 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 Pfam PF01297 Zinc-uptake complex component A periplasmic 32 305 3.9E-80 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 SUPERFAMILY SSF50814 321 502 5.41E-80 T 28-03-2018 IPR012674 Calycin CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00690 Adhesin family signature 60 73 9.2E-14 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00690 Adhesin family signature 246 264 9.2E-14 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00690 Adhesin family signature 193 214 9.2E-14 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00690 Adhesin family signature 29 47 9.2E-14 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 PRINTS PR00690 Adhesin family signature 73 90 9.2E-14 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS00825 fde9890f6bafea57a51f6fd96f77786c 502 Gene3D G3DSA:3.40.50.1980 188 306 6.3E-36 T 28-03-2018 CWM22_RS02335 b872a16c50336ced1cb398e8dc73a6ff 754 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 8 752 3.4E-263 T 28-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWM22_RS02335 b872a16c50336ced1cb398e8dc73a6ff 754 Pfam PF00343 Carbohydrate phosphorylase 79 752 3.5E-253 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWM22_RS02335 b872a16c50336ced1cb398e8dc73a6ff 754 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 596 608 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWM22_RS02335 b872a16c50336ced1cb398e8dc73a6ff 754 SUPERFAMILY SSF53756 7 753 3.37E-248 T 28-03-2018 CWM22_RS02335 b872a16c50336ced1cb398e8dc73a6ff 754 Gene3D G3DSA:3.40.50.2000 1 418 1.1E-130 T 28-03-2018 CWM22_RS02335 b872a16c50336ced1cb398e8dc73a6ff 754 Gene3D G3DSA:3.40.50.2000 419 738 1.2E-114 T 28-03-2018 CWM22_RS02335 b872a16c50336ced1cb398e8dc73a6ff 754 PIRSF PIRSF000460 2 754 5.5E-194 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 12 506 2.1E-168 T 28-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 SMART SM00487 246 512 0.0033 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 Pfam PF13307 Helicase C-terminal domain 651 797 6.6E-26 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 11 170 3.5E-26 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 SUPERFAMILY SSF52540 574 588 8.02E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 SUPERFAMILY SSF52540 616 782 8.02E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 SUPERFAMILY SSF52540 400 472 8.02E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 SUPERFAMILY SSF52540 265 316 8.02E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 SMART SM00479 12 176 8.2E-37 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 Gene3D G3DSA:3.30.420.10 1 178 1.8E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 Gene3D G3DSA:3.40.50.300 621 797 1.2E-15 T 28-03-2018 CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 SMART SM00491 659 788 2.1E-11 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 Gene3D G3DSA:3.40.50.300 228 605 3.5E-18 T 28-03-2018 CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 Pfam PF00929 Exonuclease 15 167 7.6E-27 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWM22_RS03490 22c75bc8b82b53a00830207017be1501 822 SUPERFAMILY SSF53098 12 229 3.96E-47 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS11370 11e66ec88fd6c4508909b8308dfa1f08 596 Gene3D G3DSA:3.40.190.10 190 344 8.8E-32 T 28-03-2018 CWM22_RS11370 11e66ec88fd6c4508909b8308dfa1f08 596 PIRSF PIRSF002741 1 582 5.7E-62 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CWM22_RS11370 11e66ec88fd6c4508909b8308dfa1f08 596 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 103 499 4.3E-68 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CWM22_RS11370 11e66ec88fd6c4508909b8308dfa1f08 596 SUPERFAMILY SSF53850 122 571 3.8E-89 T 28-03-2018 CWM22_RS11370 11e66ec88fd6c4508909b8308dfa1f08 596 Gene3D G3DSA:3.90.76.10 70 189 7.3E-15 T 28-03-2018 CWM22_RS11370 11e66ec88fd6c4508909b8308dfa1f08 596 Gene3D G3DSA:3.10.105.10 345 553 6.2E-41 T 28-03-2018 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 Pfam PF00453 Ribosomal protein L20 3 109 3.3E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.7E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.7E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.7E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.439 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 SUPERFAMILY SSF74731 3 116 3.4E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 Gene3D G3DSA:1.10.1900.20 55 116 2.0E-29 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 70 2.0E-13 T 28-03-2018 CWM22_RS07750 4a7c533f7b1900e99bd9d81da203de89 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.2E-50 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 SUPERFAMILY SSF50447 175 297 2.7E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 SUPERFAMILY SSF54980 301 379 5.04E-20 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.7E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Gene3D G3DSA:3.30.70.240 400 559 3.7E-30 T 28-03-2018 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Gene3D G3DSA:3.30.70.870 297 376 5.1E-29 T 28-03-2018 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 SMART SM00838 407 495 3.2E-5 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Pfam PF14492 Elongation Factor G, domain II 301 374 2.4E-6 T 28-03-2018 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Pfam PF00679 Elongation factor G C-terminus 408 495 6.9E-25 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 184 3.6E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Gene3D G3DSA:2.40.30.10 197 296 2.5E-25 T 28-03-2018 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 308.826 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 SUPERFAMILY SSF52540 9 214 1.26E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 SUPERFAMILY SSF54980 408 503 8.63E-27 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 1.9E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 3.4E-50 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Gene3D G3DSA:3.40.50.300 8 194 2.8E-37 T 28-03-2018 CWM22_RS06910 d96d5a44c02f2ab6b51354ba22654b0b 610 Pfam PF03144 Elongation factor Tu domain 2 214 284 3.2E-8 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWM22_RS10795 9399cffa4d0c59995de37a09ba659943 286 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 8 277 8.1E-102 T 28-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CWM22_RS10795 9399cffa4d0c59995de37a09ba659943 286 Pfam PF02219 Methylenetetrahydrofolate reductase 6 276 1.2E-70 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWM22_RS10795 9399cffa4d0c59995de37a09ba659943 286 SUPERFAMILY SSF51730 5 279 1.1E-77 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CWM22_RS10795 9399cffa4d0c59995de37a09ba659943 286 Gene3D G3DSA:3.20.20.220 3 284 2.6E-81 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.213 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 SMART SM01383 42 118 3.1E-46 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 SUPERFAMILY SSF50249 3 125 4.46E-51 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 Gene3D G3DSA:4.10.950.10 197 275 9.0E-34 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 Gene3D G3DSA:2.30.30.30 119 195 7.3E-33 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 9.6E-56 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 SUPERFAMILY SSF50104 126 273 6.02E-58 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 1.4E-135 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 Gene3D G3DSA:2.40.50.140 1 114 1.3E-48 T 28-03-2018 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.5E-33 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 PIRSF PIRSF002158 5 276 6.1E-98 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00510 27c99c310ffbc70955b901f3cbbe38e4 277 SMART SM01382 124 253 8.4E-88 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 Pfam PF13365 Trypsin-like peptidase domain 103 248 1.6E-28 T 28-03-2018 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 SUPERFAMILY SSF50494 58 285 4.52E-53 T 28-03-2018 IPR009003 Peptidase S1, PA clan CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 Gene3D G3DSA:2.30.42.10 296 398 7.9E-22 T 28-03-2018 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 SUPERFAMILY SSF50156 322 391 2.0E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 Pfam PF13180 PDZ domain 293 389 3.1E-20 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 PRINTS PR00834 HtrA/DegQ protease family signature 136 156 6.6E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 PRINTS PR00834 HtrA/DegQ protease family signature 177 201 6.6E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 PRINTS PR00834 HtrA/DegQ protease family signature 338 350 6.6E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 PRINTS PR00834 HtrA/DegQ protease family signature 115 127 6.6E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 PRINTS PR00834 HtrA/DegQ protease family signature 219 236 6.6E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 PRINTS PR00834 HtrA/DegQ protease family signature 241 258 6.6E-32 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 SMART SM00228 293 380 2.1E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 Gene3D G3DSA:2.40.10.10 53 177 1.5E-27 T 28-03-2018 CWM22_RS13420 267466f96d4e1a0d1537546cb9377864 398 Gene3D G3DSA:2.40.10.10 178 295 2.6E-33 T 28-03-2018 CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Gene3D G3DSA:2.60.120.260 784 928 1.1E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Gene3D G3DSA:2.60.120.260 490 671 1.7E-45 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Gene3D G3DSA:1.20.1270.90 1198 1272 4.2E-6 T 28-03-2018 CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 38 3.6E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Gene3D G3DSA:2.60.40.10 672 783 1.1E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Pfam PF04650 YSIRK type signal peptide 7 32 9.6E-12 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Pfam PF03644 Glycosyl hydrolase family 85 207 508 1.3E-73 T 28-03-2018 IPR005201 Glycoside hydrolase, family 85 GO:0005737|GO:0033925 KEGG: 00511+3.2.1.96|Reactome: R-HSA-532668 CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 SMART SM01208 1352 1426 1.0E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Pfam PF07501 G5 domain 1364 1424 1.3E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Pfam PF07523 Bacterial Ig-like domain (group 3) 1126 1192 1.5E-8 T 28-03-2018 IPR022038 Bacterial Ig-like domain CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Gene3D G3DSA:2.20.230.10 1360 1429 1.7E-4 T 28-03-2018 CWM22_RS11655 e4cec206fc6c5508ff6a0ac3414cb6a5 1491 Gene3D G3DSA:3.20.20.80 136 489 7.7E-72 T 28-03-2018 CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 TIGRFAM TIGR01857 FGAM-synthase: phosphoribosylformylglycinamidine synthase 3 1236 0.0 T 28-03-2018 IPR010141 Phosphoribosylformylglycinamidine synthase, FGAM CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 SUPERFAMILY SSF55326 626 809 1.57E-37 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 SUPERFAMILY SSF56042 438 604 4.04E-37 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 Gene3D G3DSA:3.30.1330.10 621 808 4.3E-19 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 Pfam PF02769 AIR synthase related protein, C-terminal domain 438 588 9.0E-23 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 SMART SM01211 974 1236 3.6E-102 T 28-03-2018 CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 Gene3D G3DSA:3.30.1280.10 80 146 0.0058 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 Gene3D G3DSA:3.90.650.10 828 945 0.0023 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 975 1236 4.4E-79 T 28-03-2018 CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 SUPERFAMILY SSF52317 975 1236 3.51E-64 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 Gene3D G3DSA:3.90.650.10 421 605 6.4E-27 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 Gene3D G3DSA:3.40.50.880 974 1237 2.1E-24 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 Gene3D G3DSA:3.30.1330.10 203 420 1.4E-46 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 SUPERFAMILY SSF56042 811 962 9.94E-12 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 SUPERFAMILY SSF55326 193 229 1.19E-31 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWM22_RS00240 c589e540726a36b2ffc828d83dc9c1ed 1239 SUPERFAMILY SSF55326 287 427 1.19E-31 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWM22_RS00810 23b1adc071710fe438e58511239a386f 147 Pfam PF13463 Winged helix DNA-binding domain 38 100 9.5E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS00810 23b1adc071710fe438e58511239a386f 147 SMART SM00347 29 131 1.2E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS00810 23b1adc071710fe438e58511239a386f 147 Gene3D G3DSA:1.10.10.10 2 147 2.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS00810 23b1adc071710fe438e58511239a386f 147 SUPERFAMILY SSF46785 20 145 7.05E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06935 5071d1c5d0484b29a3c71d9eb56a9bf0 170 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 16 38 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CWM22_RS06935 5071d1c5d0484b29a3c71d9eb56a9bf0 170 PRINTS PR00070 Dihydrofolate reductase signature 43 54 6.6E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWM22_RS06935 5071d1c5d0484b29a3c71d9eb56a9bf0 170 PRINTS PR00070 Dihydrofolate reductase signature 30 38 6.6E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWM22_RS06935 5071d1c5d0484b29a3c71d9eb56a9bf0 170 PRINTS PR00070 Dihydrofolate reductase signature 16 26 6.6E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWM22_RS06935 5071d1c5d0484b29a3c71d9eb56a9bf0 170 PRINTS PR00070 Dihydrofolate reductase signature 98 112 6.6E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWM22_RS06935 5071d1c5d0484b29a3c71d9eb56a9bf0 170 Pfam PF00186 Dihydrofolate reductase 4 167 6.4E-51 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWM22_RS06935 5071d1c5d0484b29a3c71d9eb56a9bf0 170 Gene3D G3DSA:3.40.430.10 1 170 2.7E-45 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWM22_RS06935 5071d1c5d0484b29a3c71d9eb56a9bf0 170 SUPERFAMILY SSF53597 1 168 9.95E-49 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWM22_RS06935 5071d1c5d0484b29a3c71d9eb56a9bf0 170 PIRSF PIRSF000194 1 170 4.2E-47 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWM22_RS00800 aad3df99615c0c9270299b6ad90a08b1 840 Pfam PF00746 LPXTG cell wall anchor motif 805 838 9.1E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS00800 aad3df99615c0c9270299b6ad90a08b1 840 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 262 599 4.3E-66 T 28-03-2018 IPR027607 SEC10/PgrA surface exclusion domain CWM22_RS00800 aad3df99615c0c9270299b6ad90a08b1 840 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 807 838 4.5E-7 T 28-03-2018 CWM22_RS00800 aad3df99615c0c9270299b6ad90a08b1 840 Gene3D G3DSA:1.10.287.620 128 288 2.9E-13 T 28-03-2018 CWM22_RS00800 aad3df99615c0c9270299b6ad90a08b1 840 Gene3D G3DSA:1.10.287.620 492 570 0.038 T 28-03-2018 CWM22_RS00800 aad3df99615c0c9270299b6ad90a08b1 840 Gene3D G3DSA:1.10.287.620 571 727 1.5E-14 T 28-03-2018 CWM22_RS07195 bbfa62e5d66141a3d144d3c980a28bf0 112 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 111 3.4E-49 T 28-03-2018 IPR004624 PhnA protein CWM22_RS07195 bbfa62e5d66141a3d144d3c980a28bf0 112 Pfam PF03831 PhnA domain 47 112 2.0E-32 T 28-03-2018 IPR013988 PhnA protein, C-terminal CWM22_RS07195 bbfa62e5d66141a3d144d3c980a28bf0 112 Gene3D G3DSA:2.20.25.10 2 40 1.2E-17 T 28-03-2018 CWM22_RS07195 bbfa62e5d66141a3d144d3c980a28bf0 112 Pfam PF08274 PhnA Zinc-Ribbon 3 31 1.8E-16 T 28-03-2018 IPR013987 PhnA protein, N-terminal CWM22_RS07195 bbfa62e5d66141a3d144d3c980a28bf0 112 SUPERFAMILY SSF82057 40 112 3.8E-27 T 28-03-2018 CWM22_RS07195 bbfa62e5d66141a3d144d3c980a28bf0 112 Gene3D G3DSA:2.30.30.40 44 111 1.0E-34 T 28-03-2018 CWM22_RS07195 bbfa62e5d66141a3d144d3c980a28bf0 112 SUPERFAMILY SSF57783 3 38 1.33E-14 T 28-03-2018 CWM22_RS10195 0c1b61baec80ae41951e9622933f74d7 263 SUPERFAMILY SSF102114 29 232 1.22E-25 T 28-03-2018 CWM22_RS10195 0c1b61baec80ae41951e9622933f74d7 263 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 14 250 1.4E-93 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 CWM22_RS10195 0c1b61baec80ae41951e9622933f74d7 263 Pfam PF04055 Radical SAM superfamily 31 196 2.1E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWM22_RS10195 0c1b61baec80ae41951e9622933f74d7 263 PIRSF PIRSF000371 4 54 9.3E-14 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWM22_RS10195 0c1b61baec80ae41951e9622933f74d7 263 PIRSF PIRSF000371 51 258 1.7E-41 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWM22_RS10195 0c1b61baec80ae41951e9622933f74d7 263 ProSitePatterns PS01087 Radical activating enzymes signature. 25 46 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CWM22_RS10195 0c1b61baec80ae41951e9622933f74d7 263 Pfam PF13353 4Fe-4S single cluster domain 23 152 4.3E-15 T 28-03-2018 CWM22_RS10195 0c1b61baec80ae41951e9622933f74d7 263 Gene3D G3DSA:3.80.30.10 76 260 7.8E-37 T 28-03-2018 CWM22_RS06185 38ad14fc636c10e9f9e1fa1ee7920dfa 230 Pfam PF00717 Peptidase S24-like 144 207 5.7E-10 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWM22_RS06185 38ad14fc636c10e9f9e1fa1ee7920dfa 230 SMART SM00530 6 61 3.3E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS06185 38ad14fc636c10e9f9e1fa1ee7920dfa 230 SUPERFAMILY SSF51306 105 225 3.31E-21 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWM22_RS06185 38ad14fc636c10e9f9e1fa1ee7920dfa 230 SUPERFAMILY SSF47413 4 64 4.83E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS06185 38ad14fc636c10e9f9e1fa1ee7920dfa 230 Pfam PF01381 Helix-turn-helix 7 61 2.7E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS06185 38ad14fc636c10e9f9e1fa1ee7920dfa 230 Gene3D G3DSA:1.10.3100.10 1 136 5.7E-20 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS06185 38ad14fc636c10e9f9e1fa1ee7920dfa 230 Gene3D G3DSA:2.10.109.10 137 228 2.0E-15 T 28-03-2018 CWM22_RS08260 dd0e93e5bc119c3a2799815b8375623b 270 Gene3D G3DSA:3.40.50.1000 1 270 2.7E-44 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08260 dd0e93e5bc119c3a2799815b8375623b 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 262 5.3E-59 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08260 dd0e93e5bc119c3a2799815b8375623b 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 234 3.0E-26 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWM22_RS08260 dd0e93e5bc119c3a2799815b8375623b 270 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 CWM22_RS08260 dd0e93e5bc119c3a2799815b8375623b 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 262 6.3E-55 T 28-03-2018 IPR000150 Cof family GO:0016787 CWM22_RS08260 dd0e93e5bc119c3a2799815b8375623b 270 SUPERFAMILY SSF56784 1 267 1.61E-69 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10890 0f31aef0c8bedf11fe24b692c1d90cc1 221 Pfam PF02517 CAAX protease self-immunity 127 212 1.0E-15 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS08760 d1fa8c178d5e87c6efec066c6776e10d 90 SUPERFAMILY SSF82771 3 75 1.96E-14 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS08760 d1fa8c178d5e87c6efec066c6776e10d 90 Pfam PF01541 GIY-YIG catalytic domain 5 75 5.5E-16 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS08760 d1fa8c178d5e87c6efec066c6776e10d 90 Gene3D G3DSA:3.40.1440.10 1 79 2.8E-8 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS11585 c934a634044b47f99b20b0fc5dd27c6e 376 Gene3D G3DSA:2.40.50.140 305 360 1.5E-13 T 28-03-2018 CWM22_RS11585 c934a634044b47f99b20b0fc5dd27c6e 376 Pfam PF00005 ABC transporter 22 163 1.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS11585 c934a634044b47f99b20b0fc5dd27c6e 376 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS11585 c934a634044b47f99b20b0fc5dd27c6e 376 SMART SM00382 30 239 5.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11585 c934a634044b47f99b20b0fc5dd27c6e 376 SUPERFAMILY SSF52540 4 256 7.91E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11585 c934a634044b47f99b20b0fc5dd27c6e 376 Gene3D G3DSA:3.40.50.300 1 249 1.4E-69 T 28-03-2018 CWM22_RS11585 c934a634044b47f99b20b0fc5dd27c6e 376 SUPERFAMILY SSF50331 248 375 3.4E-28 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CWM22_RS11585 c934a634044b47f99b20b0fc5dd27c6e 376 Gene3D G3DSA:2.40.50.100 251 304 5.2E-14 T 28-03-2018 CWM22_RS11585 c934a634044b47f99b20b0fc5dd27c6e 376 Pfam PF03459 TOBE domain 310 365 3.0E-8 T 28-03-2018 IPR005116 Transport-associated OB, type 1 CWM22_RS07395 fa7bf0d79f992104edc115c20edd90de 227 SUPERFAMILY SSF56784 3 227 4.14E-46 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS07395 fa7bf0d79f992104edc115c20edd90de 227 Gene3D G3DSA:1.10.150.240 17 87 4.1E-21 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWM22_RS07395 fa7bf0d79f992104edc115c20edd90de 227 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 226 6.6E-62 T 28-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CWM22_RS07395 fa7bf0d79f992104edc115c20edd90de 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 2.7E-23 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS07395 fa7bf0d79f992104edc115c20edd90de 227 Gene3D G3DSA:3.40.50.1000 88 227 6.4E-30 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS07395 fa7bf0d79f992104edc115c20edd90de 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 86 194 2.4E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 SUPERFAMILY SSF55681 156 495 1.72E-120 T 28-03-2018 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 Gene3D G3DSA:2.40.50.140 9 149 8.2E-43 T 28-03-2018 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 PIRSF PIRSF039101 2 496 2.7E-196 T 28-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 SUPERFAMILY SSF50249 8 149 4.41E-44 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 Pfam PF01336 OB-fold nucleic acid binding domain 65 138 6.8E-14 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 Gene3D G3DSA:3.30.930.10 150 495 3.0E-105 T 28-03-2018 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 495 1.2E-79 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 3.3E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 380 396 3.3E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 3.3E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 3.3E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 3.3E-38 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 15 496 44.27 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWM22_RS10065 c77608b30c614ecc95d641a82e08079b 496 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 9 496 1.9E-214 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWM22_RS07955 1763b22949cc96363641c27105195561 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 422 436 7.1E-25 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 550 7.1E-25 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 613 632 7.1E-25 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 273 287 7.1E-25 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 561 571 7.1E-25 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 636 648 7.1E-25 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 Gene3D G3DSA:1.20.1110.10 122 436 4.0E-32 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 644 669 3.3E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS07955 1763b22949cc96363641c27105195561 727 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 613 629 3.3E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS07955 1763b22949cc96363641c27105195561 727 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 586 602 3.3E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS07955 1763b22949cc96363641c27105195561 727 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 162 720 5.5E-156 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWM22_RS07955 1763b22949cc96363641c27105195561 727 SUPERFAMILY SSF56784 474 720 3.63E-49 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS07955 1763b22949cc96363641c27105195561 727 SUPERFAMILY SSF56784 423 440 3.63E-49 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS07955 1763b22949cc96363641c27105195561 727 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 144 723 6.8E-170 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 200 692 3.1E-82 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS07955 1763b22949cc96363641c27105195561 727 SUPERFAMILY SSF81665 178 231 1.7E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS07955 1763b22949cc96363641c27105195561 727 SUPERFAMILY SSF81665 324 414 1.7E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS07955 1763b22949cc96363641c27105195561 727 Pfam PF00122 E1-E2 ATPase 236 394 1.1E-44 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 424 430 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWM22_RS07955 1763b22949cc96363641c27105195561 727 Pfam PF00702 haloacid dehalogenase-like hydrolase 420 627 8.0E-36 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 Gene3D G3DSA:1.20.1110.10 576 727 4.0E-26 T 28-03-2018 CWM22_RS07955 1763b22949cc96363641c27105195561 727 SUPERFAMILY SSF81653 240 323 3.53E-21 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWM22_RS07955 1763b22949cc96363641c27105195561 727 Gene3D G3DSA:3.40.1110.10 437 575 1.0E-25 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWM22_RS07225 da655aec9f0f990e1d45e3150130c213 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 2.4E-36 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07225 da655aec9f0f990e1d45e3150130c213 104 SUPERFAMILY SSF141091 4 103 7.72E-36 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07225 da655aec9f0f990e1d45e3150130c213 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 104 25.049 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07225 da655aec9f0f990e1d45e3150130c213 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 3.1E-34 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07225 da655aec9f0f990e1d45e3150130c213 104 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS04675 241dbb9f0ac99ad06d7fb0c3a941a2b1 269 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 25 266 7.5E-100 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CWM22_RS04675 241dbb9f0ac99ad06d7fb0c3a941a2b1 269 PIRSF PIRSF000477 2 269 4.2E-104 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CWM22_RS04675 241dbb9f0ac99ad06d7fb0c3a941a2b1 269 SUPERFAMILY SSF53167 3 269 5.42E-87 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWM22_RS04675 241dbb9f0ac99ad06d7fb0c3a941a2b1 269 Pfam PF01048 Phosphorylase superfamily 24 267 9.3E-49 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWM22_RS04675 241dbb9f0ac99ad06d7fb0c3a941a2b1 269 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 24 266 6.0E-101 T 28-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CWM22_RS04675 241dbb9f0ac99ad06d7fb0c3a941a2b1 269 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 76 117 - T 28-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CWM22_RS04675 241dbb9f0ac99ad06d7fb0c3a941a2b1 269 Gene3D G3DSA:3.40.50.1580 1 269 1.4E-61 T 28-03-2018 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 9.1E-27 T 28-03-2018 IPR000362 Fumarate lyase family CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 9.1E-27 T 28-03-2018 IPR000362 Fumarate lyase family CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 9.1E-27 T 28-03-2018 IPR000362 Fumarate lyase family CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 9.1E-27 T 28-03-2018 IPR000362 Fumarate lyase family CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 4.4E-25 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 SMART SM00998 349 429 2.0E-40 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 Gene3D G3DSA:1.20.200.10 93 348 4.8E-75 T 28-03-2018 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 Gene3D G3DSA:1.10.275.10 2 92 4.5E-25 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 Gene3D G3DSA:1.10.40.30 349 428 5.2E-27 T 28-03-2018 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 4.9E-172 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 SUPERFAMILY SSF48557 3 427 1.46E-135 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 Pfam PF00206 Lyase 7 286 4.4E-69 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 2.5E-10 T 28-03-2018 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 2.5E-10 T 28-03-2018 CWM22_RS00340 96fcf2739cc856feea9a6df10f8cc966 430 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 2.5E-10 T 28-03-2018 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 379 26.648 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 Pfam PF08529 NusA N-terminal domain 4 123 1.2E-30 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 SMART SM00316 133 199 8.9E-4 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 Pfam PF00575 S1 RNA binding domain 132 193 5.6E-5 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 356 1.4E-110 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 Gene3D G3DSA:3.30.300.20 287 356 3.3E-15 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 Gene3D G3DSA:3.30.300.20 198 286 6.3E-30 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 Pfam PF13184 NusA-like KH domain 229 310 1.4E-28 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 SMART SM00322 315 373 4.8E-6 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 SMART SM00322 229 306 1.7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 SUPERFAMILY SSF54814 292 357 5.1E-16 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 SUPERFAMILY SSF50249 132 198 1.06E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 SUPERFAMILY SSF69705 1 124 3.66E-34 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 SUPERFAMILY SSF54814 199 271 3.47E-22 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 Gene3D G3DSA:3.30.1480.10 1 129 1.7E-37 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CWM22_RS11275 6b746d2af318601d5c60b557dbe9c4cc 384 Gene3D G3DSA:2.40.50.140 136 197 1.4E-12 T 28-03-2018 CWM22_RS08695 6a0e568989db7aada5be586bae031554 291 Gene3D G3DSA:1.10.3720.10 2 284 4.5E-43 T 28-03-2018 CWM22_RS08695 6a0e568989db7aada5be586bae031554 291 SUPERFAMILY SSF161098 56 281 1.7E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS08695 6a0e568989db7aada5be586bae031554 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 284 6.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS08815 5d5bc696a416103aeea679d4517c8478 127 SUPERFAMILY SSF50729 6 125 1.72E-38 T 28-03-2018 IPR011993 PH domain-like CWM22_RS08815 5d5bc696a416103aeea679d4517c8478 127 Pfam PF08000 Bacterial PH domain 2 123 2.4E-47 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain CWM22_RS08815 5d5bc696a416103aeea679d4517c8478 127 Gene3D G3DSA:2.30.29.50 13 101 1.6E-35 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 190 200 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 375 45.094 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 SUPERFAMILY SSF51161 291 362 2.98E-11 T 28-03-2018 IPR011004 Trimeric LpxA-like CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 Pfam PF00483 Nucleotidyl transferase 8 259 4.5E-71 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 SUPERFAMILY SSF53448 3 263 3.18E-85 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 SUPERFAMILY SSF53448 324 340 3.18E-85 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 360 2.7E-135 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 Gene3D G3DSA:2.160.10.10 268 372 2.1E-11 T 28-03-2018 CWM22_RS05950 2b34486303797a66c7dafe64d0b79b41 375 Gene3D G3DSA:3.90.550.10 1 267 2.6E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS00245 8ccdbe161b30c3d412babc0ebb17df91 484 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 457 45.737 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CWM22_RS00245 8ccdbe161b30c3d412babc0ebb17df91 484 SUPERFAMILY SSF53271 248 465 2.23E-72 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS00245 8ccdbe161b30c3d412babc0ebb17df91 484 PIRSF PIRSF000485 8 474 7.5E-176 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CWM22_RS00245 8ccdbe161b30c3d412babc0ebb17df91 484 Gene3D G3DSA:3.40.50.2020 242 439 1.7E-36 T 28-03-2018 CWM22_RS00245 8ccdbe161b30c3d412babc0ebb17df91 484 SUPERFAMILY SSF56235 12 254 7.46E-67 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWM22_RS00245 8ccdbe161b30c3d412babc0ebb17df91 484 Pfam PF13537 Glutamine amidotransferase domain 92 210 1.2E-18 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CWM22_RS00245 8ccdbe161b30c3d412babc0ebb17df91 484 Gene3D G3DSA:3.60.20.10 12 241 8.6E-57 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWM22_RS00245 8ccdbe161b30c3d412babc0ebb17df91 484 Pfam PF00156 Phosphoribosyl transferase domain 278 384 6.7E-10 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWM22_RS00245 8ccdbe161b30c3d412babc0ebb17df91 484 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 458 1.6E-158 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CWM22_RS11725 f2a461e071820ce0ab1f8f6a50d304c6 436 TIGRFAM TIGR03173 pbuX: xanthine permease 29 433 6.1E-143 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CWM22_RS11725 f2a461e071820ce0ab1f8f6a50d304c6 436 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 349 369 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWM22_RS11725 f2a461e071820ce0ab1f8f6a50d304c6 436 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 23 431 9.0E-114 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWM22_RS11725 f2a461e071820ce0ab1f8f6a50d304c6 436 Pfam PF00860 Permease family 26 401 1.6E-88 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWM22_RS07570 810199d0f06e71c27bf9e16d6a9b580d 556 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 556 48.899 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWM22_RS07570 810199d0f06e71c27bf9e16d6a9b580d 556 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 328 339 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWM22_RS07570 810199d0f06e71c27bf9e16d6a9b580d 556 Gene3D G3DSA:3.10.410.10 444 532 3.8E-36 T 28-03-2018 CWM22_RS07570 810199d0f06e71c27bf9e16d6a9b580d 556 SUPERFAMILY SSF52540 4 554 1.06E-239 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07570 810199d0f06e71c27bf9e16d6a9b580d 556 Gene3D G3DSA:3.40.50.300 234 442 3.9E-69 T 28-03-2018 CWM22_RS07570 810199d0f06e71c27bf9e16d6a9b580d 556 Gene3D G3DSA:3.40.50.300 12 233 2.2E-92 T 28-03-2018 CWM22_RS07570 810199d0f06e71c27bf9e16d6a9b580d 556 Pfam PF01268 Formate--tetrahydrofolate ligase 2 556 3.1E-262 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWM22_RS07570 810199d0f06e71c27bf9e16d6a9b580d 556 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWM22_RS11360 bdb2252f1024fb8eaa0c01040c851f99 313 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS11360 bdb2252f1024fb8eaa0c01040c851f99 313 Pfam PF00005 ABC transporter 31 181 2.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS11360 bdb2252f1024fb8eaa0c01040c851f99 313 SUPERFAMILY SSF52540 4 253 1.19E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11360 bdb2252f1024fb8eaa0c01040c851f99 313 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 271 8.0E-7 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWM22_RS11360 bdb2252f1024fb8eaa0c01040c851f99 313 SMART SM00382 39 231 2.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11360 bdb2252f1024fb8eaa0c01040c851f99 313 Gene3D G3DSA:3.40.50.300 2 292 1.1E-70 T 28-03-2018 CWM22_RS07630 ee5b599b99dce0b6ad65f3afe180216f 289 Gene3D G3DSA:3.40.50.10860 1 118 6.0E-41 T 28-03-2018 CWM22_RS07630 ee5b599b99dce0b6ad65f3afe180216f 289 SUPERFAMILY SSF53223 1 106 4.6E-35 T 28-03-2018 CWM22_RS07630 ee5b599b99dce0b6ad65f3afe180216f 289 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 285 33.511 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWM22_RS07630 ee5b599b99dce0b6ad65f3afe180216f 289 SUPERFAMILY SSF51735 107 285 5.58E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS07630 ee5b599b99dce0b6ad65f3afe180216f 289 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 9 282 7.0E-66 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWM22_RS07630 ee5b599b99dce0b6ad65f3afe180216f 289 Gene3D G3DSA:3.40.50.720 119 289 5.4E-26 T 28-03-2018 CWM22_RS07630 ee5b599b99dce0b6ad65f3afe180216f 289 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 8.5E-28 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWM22_RS09370 3c2b9772eab38ed7c85ce1defb4c30f8 611 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 577 608 1.1E-5 T 28-03-2018 CWM22_RS09370 3c2b9772eab38ed7c85ce1defb4c30f8 611 Pfam PF00746 LPXTG cell wall anchor motif 571 607 9.8E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS09370 3c2b9772eab38ed7c85ce1defb4c30f8 611 Pfam PF03577 Peptidase family C69 25 442 1.8E-68 T 28-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 CWM22_RS09370 3c2b9772eab38ed7c85ce1defb4c30f8 611 Gene3D G3DSA:3.60.60.10 23 299 3.3E-42 T 28-03-2018 CWM22_RS03695 ae2a771dee7124c726865964c41a0c3c 295 Pfam PF03668 P-loop ATPase protein family 6 288 2.1E-105 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CWM22_RS03695 ae2a771dee7124c726865964c41a0c3c 295 SUPERFAMILY SSF52540 7 158 7.77E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03695 ae2a771dee7124c726865964c41a0c3c 295 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 5 287 41.799 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CWM22_RS03695 ae2a771dee7124c726865964c41a0c3c 295 PIRSF PIRSF005052 5 290 9.4E-108 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CWM22_RS03695 ae2a771dee7124c726865964c41a0c3c 295 Gene3D G3DSA:3.40.50.300 2 164 2.9E-8 T 28-03-2018 CWM22_RS05115 5fa2a9349ab08598f262b793c57ace02 355 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 44 353 2.3E-69 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CWM22_RS05115 5fa2a9349ab08598f262b793c57ace02 355 Gene3D G3DSA:3.40.50.2300 160 353 6.6E-47 T 28-03-2018 CWM22_RS05115 5fa2a9349ab08598f262b793c57ace02 355 SUPERFAMILY SSF53822 61 271 3.06E-18 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS05115 5fa2a9349ab08598f262b793c57ace02 355 Gene3D G3DSA:3.40.50.2300 39 159 1.3E-40 T 28-03-2018 CWM22_RS02135 a220f65610296350d124219e31f773b7 262 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 262 124.048 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CWM22_RS02135 a220f65610296350d124219e31f773b7 262 PIRSF PIRSF011572 1 261 2.2E-115 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CWM22_RS02135 a220f65610296350d124219e31f773b7 262 Pfam PF06018 CodY GAF-like domain 3 182 3.9E-68 T 28-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CWM22_RS02135 a220f65610296350d124219e31f773b7 262 SUPERFAMILY SSF46785 173 260 8.88E-40 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02135 a220f65610296350d124219e31f773b7 262 SUPERFAMILY SSF55781 29 168 2.85E-5 T 28-03-2018 IPR029016 GAF domain-like CWM22_RS02135 a220f65610296350d124219e31f773b7 262 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 4 257 1.1E-119 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CWM22_RS02135 a220f65610296350d124219e31f773b7 262 Gene3D G3DSA:1.10.10.10 164 260 2.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02135 a220f65610296350d124219e31f773b7 262 Gene3D G3DSA:3.30.450.40 1 163 3.7E-29 T 28-03-2018 IPR029016 GAF domain-like CWM22_RS02135 a220f65610296350d124219e31f773b7 262 Pfam PF08222 CodY helix-turn-helix domain 202 259 1.1E-34 T 28-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 SMART SM00116 163 211 6.1E-9 T 28-03-2018 IPR000644 CBS domain CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 SMART SM00116 100 150 9.2E-8 T 28-03-2018 IPR000644 CBS domain CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 SUPERFAMILY SSF51412 7 94 1.16E-122 T 28-03-2018 CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 SUPERFAMILY SSF51412 222 483 1.16E-122 T 28-03-2018 CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 Pfam PF00571 CBS domain 100 146 3.3E-7 T 28-03-2018 IPR000644 CBS domain CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 Pfam PF00571 CBS domain 161 206 1.4E-6 T 28-03-2018 IPR000644 CBS domain CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 Gene3D G3DSA:3.20.20.70 5 489 2.7E-110 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 SUPERFAMILY SSF54631 68 210 8.72E-29 T 28-03-2018 CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 492 83.938 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 PIRSF PIRSF000130 3 493 9.4E-210 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 479 6.3E-161 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 461 1.0E-195 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 300 312 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CWM22_RS13370 c5df4afcd89b4539774e7f4c860d552f 493 SMART SM01240 11 479 0.0 T 28-03-2018 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 PIRSF PIRSF000114 1 335 1.5E-102 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 4 325 36.135 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 323 5.4E-52 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 SUPERFAMILY SSF51735 5 181 2.15E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 SUPERFAMILY SSF48179 182 334 1.22E-53 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 Gene3D G3DSA:1.10.1040.10 183 333 1.9E-53 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 2.6E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 8 25 2.6E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 2.6E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 2.6E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 2.6E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 58 85 2.6E-41 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 Gene3D G3DSA:3.40.50.720 1 182 8.7E-36 T 28-03-2018 CWM22_RS12425 b636e4502dfff88fa15f74f91da94f73 338 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 6 162 5.5E-52 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWM22_RS10295 7c759fb3d69f36fe719f96038bf5238b 72 SUPERFAMILY SSF158379 1 62 6.15E-24 T 28-03-2018 IPR023164 YqgQ-like domain CWM22_RS10295 7c759fb3d69f36fe719f96038bf5238b 72 Gene3D G3DSA:1.10.287.760 1 65 1.3E-29 T 28-03-2018 IPR023164 YqgQ-like domain CWM22_RS10295 7c759fb3d69f36fe719f96038bf5238b 72 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 60 3.3E-29 T 28-03-2018 IPR009256 Protein of unknown function DUF910 CWM22_RS07505 22f6e5607057b334e6c681b99a72fa59 814 Pfam PF01228 Glycine radical 692 796 4.2E-31 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CWM22_RS07505 22f6e5607057b334e6c681b99a72fa59 814 PIRSF PIRSF000379 98 197 81.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CWM22_RS07505 22f6e5607057b334e6c681b99a72fa59 814 PIRSF PIRSF000379 172 814 1.5E-154 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CWM22_RS07505 22f6e5607057b334e6c681b99a72fa59 814 ProSitePatterns PS00850 Glycine radical domain signature. 785 793 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CWM22_RS07505 22f6e5607057b334e6c681b99a72fa59 814 Gene3D G3DSA:3.20.70.20 20 814 2.3E-286 T 28-03-2018 CWM22_RS07505 22f6e5607057b334e6c681b99a72fa59 814 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 20 814 2.4E-281 T 28-03-2018 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CWM22_RS07505 22f6e5607057b334e6c681b99a72fa59 814 Pfam PF02901 Pyruvate formate lyase-like 21 675 4.6E-211 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CWM22_RS07505 22f6e5607057b334e6c681b99a72fa59 814 SUPERFAMILY SSF51998 19 813 7.94E-232 T 28-03-2018 CWM22_RS03635 4860b030db5ff76f9c06a9e40b1ad995 306 Pfam PF12784 PD-(D/E)XK nuclease family transposase 13 229 1.3E-19 T 28-03-2018 CWM22_RS03635 4860b030db5ff76f9c06a9e40b1ad995 306 Gene3D G3DSA:1.10.10.60 248 299 7.0E-8 T 28-03-2018 CWM22_RS03635 4860b030db5ff76f9c06a9e40b1ad995 306 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 12 298 4.8E-28 T 28-03-2018 IPR010106 Recombination-promoting nuclease RpnA CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 SUPERFAMILY SSF53335 1 231 8.66E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 SUPERFAMILY SSF53335 295 357 8.66E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 Gene3D G3DSA:3.40.50.150 1 188 5.5E-68 T 28-03-2018 CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 338 356 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 Gene3D G3DSA:3.90.120.10 189 344 1.6E-19 T 28-03-2018 CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 357 1.3E-90 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 68 80 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 356 1.1E-88 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 153 166 1.9E-19 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 1.9E-19 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS03995 79694573fd92b51d15b9b7e6143bc6b8 361 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 107 121 1.9E-19 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 SMART SM00851 14 129 8.0E-51 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 SMART SM00798 134 450 1.7E-188 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 449 4.2E-114 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 SUPERFAMILY SSF53927 209 515 1.2E-117 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 Gene3D G3DSA:3.40.50.1380 1 192 3.4E-72 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 Pfam PF02142 MGS-like domain 14 128 1.3E-23 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 Gene3D G3DSA:3.40.140.20 364 505 2.1E-48 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 515 43.677 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 PIRSF PIRSF000414 1 515 3.8E-206 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 Gene3D G3DSA:3.40.140.20 218 362 8.4E-50 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 515 6.7E-212 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00265 0bb98db8bb1980eb7db3a3bda5b6696b 515 SUPERFAMILY SSF52335 2 194 1.45E-69 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWM22_RS06785 a613a35212792c4178e5ac759fe45b18 412 Pfam PF01719 Plasmid replication protein 9 176 5.6E-40 T 28-03-2018 IPR002631 Plasmid replication protein GO:0003677|GO:0003916|GO:0005727|GO:0006260 CWM22_RS06785 a613a35212792c4178e5ac759fe45b18 412 SUPERFAMILY SSF52540 150 407 3.38E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06785 a613a35212792c4178e5ac759fe45b18 412 Pfam PF00910 RNA helicase 219 286 7.1E-7 T 28-03-2018 IPR000605 Helicase, superfamily 3, single-stranded DNA/RNA virus GO:0003723|GO:0003724 CWM22_RS06785 a613a35212792c4178e5ac759fe45b18 412 Gene3D G3DSA:3.40.50.300 129 396 2.6E-14 T 28-03-2018 CWM22_RS01235 80b110995d6c46b64526d8a020f75d22 851 Pfam PF16828 GAG-binding domain on surface antigen 51 197 1.6E-39 T 28-03-2018 IPR031792 Surface antigen, GAG-binding domain CWM22_RS01235 80b110995d6c46b64526d8a020f75d22 851 Gene3D G3DSA:2.20.230.10 707 783 1.8E-15 T 28-03-2018 CWM22_RS01235 80b110995d6c46b64526d8a020f75d22 851 Pfam PF07501 G5 domain 709 780 2.2E-14 T 28-03-2018 IPR011098 G5 domain CWM22_RS01235 80b110995d6c46b64526d8a020f75d22 851 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 5 33 7.6E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS01235 80b110995d6c46b64526d8a020f75d22 851 Pfam PF04650 YSIRK type signal peptide 5 30 4.3E-12 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS01235 80b110995d6c46b64526d8a020f75d22 851 Pfam PF00746 LPXTG cell wall anchor motif 808 845 4.2E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS01235 80b110995d6c46b64526d8a020f75d22 851 SMART SM01208 706 783 1.2E-18 T 28-03-2018 IPR011098 G5 domain CWM22_RS03690 9f979e35d0f29d01c2ca932da05073d2 125 SUPERFAMILY SSF55298 2 125 6.13E-47 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWM22_RS03690 9f979e35d0f29d01c2ca932da05073d2 125 Gene3D G3DSA:3.30.1330.40 1 125 2.1E-47 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWM22_RS03690 9f979e35d0f29d01c2ca932da05073d2 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 1 123 6.9E-54 T 28-03-2018 IPR006056 RidA family CWM22_RS03690 9f979e35d0f29d01c2ca932da05073d2 125 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 100 118 - T 28-03-2018 IPR019897 RidA, conserved site CWM22_RS03690 9f979e35d0f29d01c2ca932da05073d2 125 Pfam PF01042 Endoribonuclease L-PSP 7 123 6.2E-45 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 Gene3D G3DSA:3.40.50.720 1 239 1.3E-51 T 28-03-2018 CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 Pfam PF00106 short chain dehydrogenase 4 194 9.4E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 SUPERFAMILY SSF51735 2 229 8.05E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 PIRSF PIRSF000126 1 241 5.5E-56 T 28-03-2018 CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 7.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 7.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS06850 4f5bfe5bd42c16dbe2c1a012b519882b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03365 fb5d0ab670ae5e185fd460608121e30d 450 SMART SM00640 27 433 4.2E-103 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CWM22_RS03365 fb5d0ab670ae5e185fd460608121e30d 450 SUPERFAMILY SSF49899 358 446 1.27E-9 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CWM22_RS03365 fb5d0ab670ae5e185fd460608121e30d 450 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 27 40 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CWM22_RS03365 fb5d0ab670ae5e185fd460608121e30d 450 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 364 444 1.3E-8 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CWM22_RS03365 fb5d0ab670ae5e185fd460608121e30d 450 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 27 326 4.2E-98 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CWM22_RS03365 fb5d0ab670ae5e185fd460608121e30d 450 Gene3D G3DSA:2.60.120.560 345 449 1.5E-10 T 28-03-2018 CWM22_RS03365 fb5d0ab670ae5e185fd460608121e30d 450 Gene3D G3DSA:2.115.10.20 32 344 1.2E-90 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWM22_RS03365 fb5d0ab670ae5e185fd460608121e30d 450 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 22 443 1.4E-113 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CWM22_RS03365 fb5d0ab670ae5e185fd460608121e30d 450 SUPERFAMILY SSF75005 18 331 3.45E-107 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWM22_RS08630 dac1912ad56007d1bfc680ad06a70c9a 251 Pfam PF02677 Uncharacterized BCR, COG1636 39 216 5.5E-64 T 28-03-2018 IPR003828 Probable epoxyqueuosine reductase QueH CWM22_RS02765 a9026df903fab9915263f12e3ba049ab 330 SUPERFAMILY SSF55681 5 330 2.11E-97 T 28-03-2018 CWM22_RS02765 a9026df903fab9915263f12e3ba049ab 330 Gene3D G3DSA:3.30.930.10 1 329 7.9E-37 T 28-03-2018 CWM22_RS02765 a9026df903fab9915263f12e3ba049ab 330 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 1 330 4.1E-186 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CWM22_RS02765 a9026df903fab9915263f12e3ba049ab 330 Pfam PF03590 Aspartate-ammonia ligase 9 243 1.3E-94 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CWM22_RS02765 a9026df903fab9915263f12e3ba049ab 330 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 1 330 46.626 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CWM22_RS02765 a9026df903fab9915263f12e3ba049ab 330 PIRSF PIRSF001555 1 330 1.4E-156 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CWM22_RS05330 1adf3e503fca26ee4a58ad6d917e87e2 114 Pfam PF08866 Putative amino acid metabolism 1 111 3.2E-44 T 28-03-2018 IPR014965 Putative amino acid metabolism CWM22_RS05330 1adf3e503fca26ee4a58ad6d917e87e2 114 SUPERFAMILY SSF160800 1 112 3.92E-44 T 28-03-2018 IPR014965 Putative amino acid metabolism CWM22_RS05330 1adf3e503fca26ee4a58ad6d917e87e2 114 Gene3D G3DSA:3.30.1820.10 2 111 9.9E-44 T 28-03-2018 IPR014965 Putative amino acid metabolism CWM22_RS05930 21803b49b40058c3fd444746b44837d0 266 Gene3D G3DSA:3.40.190.10 188 264 6.6E-12 T 28-03-2018 CWM22_RS05930 21803b49b40058c3fd444746b44837d0 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 258 7.3E-58 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS05930 21803b49b40058c3fd444746b44837d0 266 SMART SM00079 37 262 4.8E-5 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CWM22_RS05930 21803b49b40058c3fd444746b44837d0 266 SMART SM00062 37 258 4.9E-57 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS05930 21803b49b40058c3fd444746b44837d0 266 SUPERFAMILY SSF53850 1 258 2.9E-67 T 28-03-2018 CWM22_RS05930 21803b49b40058c3fd444746b44837d0 266 Gene3D G3DSA:3.40.190.10 26 187 7.3E-42 T 28-03-2018 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 TIGRFAM TIGR00131 gal_kin: galactokinase 4 385 1.2E-118 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 Gene3D G3DSA:3.30.70.890 209 386 1.7E-50 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 PRINTS PR00473 Galactokinase signature 91 102 4.2E-29 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 PRINTS PR00473 Galactokinase signature 112 130 4.2E-29 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 PRINTS PR00473 Galactokinase signature 26 44 4.2E-29 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 PRINTS PR00473 Galactokinase signature 269 283 4.2E-29 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 SUPERFAMILY SSF55060 206 386 3.42E-55 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 Gene3D G3DSA:3.30.230.10 2 208 1.6E-54 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 SUPERFAMILY SSF54211 4 203 7.13E-63 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 PRINTS PR00959 Mevalonate kinase family signature 119 141 2.1E-42 T 28-03-2018 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 PRINTS PR00959 Mevalonate kinase family signature 162 181 2.1E-42 T 28-03-2018 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 PRINTS PR00959 Mevalonate kinase family signature 24 48 2.1E-42 T 28-03-2018 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 PRINTS PR00959 Mevalonate kinase family signature 333 350 2.1E-42 T 28-03-2018 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 Pfam PF00288 GHMP kinases N terminal domain 115 181 7.1E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 PIRSF PIRSF000530 1 388 1.1E-120 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 Hamap MF_00246 Galactokinase [galK]. 24 386 49.244 T 28-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 Pfam PF08544 GHMP kinases C terminal 284 365 1.7E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS02205 53e950231f1ee58517531a107ff1ec37 390 Pfam PF10509 Galactokinase galactose-binding signature 9 57 8.1E-22 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS11365 7bc6ec2ff491d536e24c3208e68b7a23 332 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS11365 7bc6ec2ff491d536e24c3208e68b7a23 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 294 1.4E-12 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWM22_RS11365 7bc6ec2ff491d536e24c3208e68b7a23 332 SMART SM00382 36 235 2.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11365 7bc6ec2ff491d536e24c3208e68b7a23 332 SUPERFAMILY SSF52540 7 257 3.63E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11365 7bc6ec2ff491d536e24c3208e68b7a23 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 321 9.2E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWM22_RS11365 7bc6ec2ff491d536e24c3208e68b7a23 332 Gene3D G3DSA:3.40.50.300 4 329 9.2E-75 T 28-03-2018 CWM22_RS11365 7bc6ec2ff491d536e24c3208e68b7a23 332 Pfam PF00005 ABC transporter 28 185 6.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 SMART SM01086 647 735 8.1E-28 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 Gene3D G3DSA:3.40.50.300 432 646 1.5E-43 T 28-03-2018 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 244 256 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 Gene3D G3DSA:1.10.8.60 292 427 1.1E-34 T 28-03-2018 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 Pfam PF02151 UvrB/uvrC motif 364 397 1.0E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 526 544 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 481 499 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 555 573 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 588 602 1.7E-37 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 Gene3D G3DSA:3.40.50.300 109 291 1.4E-24 T 28-03-2018 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 SMART SM00382 148 289 4.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 SMART SM00382 477 648 4.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 SUPERFAMILY SSF52540 110 362 1.09E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 SUPERFAMILY SSF52540 402 407 1.09E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 511 529 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 153 272 4.4E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 Gene3D G3DSA:1.10.8.60 647 742 2.6E-23 T 28-03-2018 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 Pfam PF07724 AAA domain (Cdc48 subfamily) 476 639 2.9E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 647 721 4.0E-23 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS02865 5e432533c6313b2392885d8dabf8920e 742 SUPERFAMILY SSF52540 426 717 1.6E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 Pfam PF00106 short chain dehydrogenase 3 185 2.5E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 Gene3D G3DSA:3.40.50.720 1 251 1.3E-47 T 28-03-2018 CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 SUPERFAMILY SSF51735 2 245 6.0E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 4.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 4.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS07960 ec5d1c42ac2b9cf69aa4a4d60996597f 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 4.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS06365 67af2a7d8fd2415d6cde15d4bbd0f1fb 63 Gene3D G3DSA:3.90.182.10 2 59 4.3E-14 T 28-03-2018 CWM22_RS06365 67af2a7d8fd2415d6cde15d4bbd0f1fb 63 SUPERFAMILY SSF103647 9 53 3.27E-5 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CWM22_RS05275 cc9084232bb1b1f4abde3fe9cbedfe29 343 Gene3D G3DSA:3.90.550.10 2 326 4.5E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05275 cc9084232bb1b1f4abde3fe9cbedfe29 343 SUPERFAMILY SSF53448 5 233 8.34E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05275 cc9084232bb1b1f4abde3fe9cbedfe29 343 Pfam PF00535 Glycosyl transferase family 2 8 124 5.5E-26 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS00840 bb7d5fb884ec8f40ea843e50acd80241 69 Pfam PF00403 Heavy-metal-associated domain 4 63 4.6E-11 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWM22_RS00840 bb7d5fb884ec8f40ea843e50acd80241 69 SUPERFAMILY SSF55008 1 66 6.94E-13 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWM22_RS00840 bb7d5fb884ec8f40ea843e50acd80241 69 Gene3D G3DSA:3.30.70.100 1 69 2.6E-14 T 28-03-2018 CWM22_RS00840 bb7d5fb884ec8f40ea843e50acd80241 69 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CWM22_RS08805 004ba661bc2a9d4543f884c08fb20591 166 Gene3D G3DSA:3.30.420.10 15 165 1.6E-9 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS08805 004ba661bc2a9d4543f884c08fb20591 166 Pfam PF13358 DDE superfamily endonuclease 16 155 1.2E-28 T 28-03-2018 CWM22_RS08805 004ba661bc2a9d4543f884c08fb20591 166 SUPERFAMILY SSF53098 62 158 2.38E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS01575 64a8e44f6bbace8114c344cd19ed0178 108 Gene3D G3DSA:1.10.10.10 7 107 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01575 64a8e44f6bbace8114c344cd19ed0178 108 Pfam PF03551 Transcriptional regulator PadR-like family 14 81 5.5E-18 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWM22_RS01575 64a8e44f6bbace8114c344cd19ed0178 108 SUPERFAMILY SSF46785 9 103 2.98E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS11005 2f8516e55931d7fb0126c908bff15a39 484 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 20 457 1.4E-161 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CWM22_RS11005 2f8516e55931d7fb0126c908bff15a39 484 SUPERFAMILY SSF49899 340 479 1.42E-25 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CWM22_RS11005 2f8516e55931d7fb0126c908bff15a39 484 Gene3D G3DSA:2.60.120.560 350 478 7.1E-22 T 28-03-2018 CWM22_RS11005 2f8516e55931d7fb0126c908bff15a39 484 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 358 467 5.5E-16 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CWM22_RS11005 2f8516e55931d7fb0126c908bff15a39 484 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 37 340 4.3E-88 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CWM22_RS11005 2f8516e55931d7fb0126c908bff15a39 484 SMART SM00640 37 446 1.1E-117 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CWM22_RS11005 2f8516e55931d7fb0126c908bff15a39 484 SUPERFAMILY SSF75005 28 341 7.71E-90 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWM22_RS11005 2f8516e55931d7fb0126c908bff15a39 484 Gene3D G3DSA:2.115.10.20 1 349 3.3E-74 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWM22_RS08795 92dccf675191fe9bdd2caeb1b1f801cf 352 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 66 199 4.0E-11 T 28-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain CWM22_RS08795 92dccf675191fe9bdd2caeb1b1f801cf 352 SUPERFAMILY SSF51695 47 268 1.1E-49 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS08795 92dccf675191fe9bdd2caeb1b1f801cf 352 SUPERFAMILY SSF51695 312 351 1.1E-49 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS08795 92dccf675191fe9bdd2caeb1b1f801cf 352 Gene3D G3DSA:3.20.20.190 43 352 7.4E-46 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS08795 92dccf675191fe9bdd2caeb1b1f801cf 352 SMART SM00148 56 202 1.5E-8 T 28-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain CWM22_RS08730 fa2e002ebe8435773984052807c9256a 386 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 7 384 4.3E-121 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CWM22_RS08730 fa2e002ebe8435773984052807c9256a 386 Pfam PF00155 Aminotransferase class I and II 35 381 2.5E-40 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWM22_RS08730 fa2e002ebe8435773984052807c9256a 386 SUPERFAMILY SSF53383 9 385 4.12E-96 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS08730 fa2e002ebe8435773984052807c9256a 386 Gene3D G3DSA:3.40.640.10 75 281 1.3E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS08730 fa2e002ebe8435773984052807c9256a 386 Gene3D G3DSA:3.90.1150.10 1 74 6.6E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS08730 fa2e002ebe8435773984052807c9256a 386 Gene3D G3DSA:3.90.1150.10 282 384 2.6E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 147 168 1.7E-24 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 1.7E-24 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 1.7E-24 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 1.7E-24 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 Pfam PF00579 tRNA synthetases class I (W and Y) 4 290 3.2E-57 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 Gene3D G3DSA:1.10.240.10 209 333 5.3E-29 T 28-03-2018 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 Gene3D G3DSA:3.40.50.620 2 208 2.7E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 SUPERFAMILY SSF52374 5 337 3.66E-78 T 28-03-2018 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 338 34.767 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CWM22_RS13375 4bfd04005980644b79b41a0d1a2b43c3 341 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 337 2.4E-75 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWM22_RS00255 345edf62f51a8060bf85233ff707d639 185 SUPERFAMILY SSF53328 2 182 2.62E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWM22_RS00255 345edf62f51a8060bf85233ff707d639 185 Gene3D G3DSA:3.40.50.170 1 185 5.7E-62 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWM22_RS00255 345edf62f51a8060bf85233ff707d639 185 Pfam PF00551 Formyl transferase 2 175 1.4E-51 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWM22_RS00255 345edf62f51a8060bf85233ff707d639 185 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 181 1.2E-63 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CWM22_RS00255 345edf62f51a8060bf85233ff707d639 185 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 181 29.979 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CWM22_RS10440 b6ed50baaed3f7f1f232c37ebfd2094f 246 SMART SM00967 29 95 9.2E-13 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWM22_RS10440 b6ed50baaed3f7f1f232c37ebfd2094f 246 Gene3D G3DSA:3.40.1280.10 95 246 1.0E-42 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWM22_RS10440 b6ed50baaed3f7f1f232c37ebfd2094f 246 SUPERFAMILY SSF55315 3 92 3.06E-20 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWM22_RS10440 b6ed50baaed3f7f1f232c37ebfd2094f 246 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 29 91 6.4E-9 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWM22_RS10440 b6ed50baaed3f7f1f232c37ebfd2094f 246 SUPERFAMILY SSF75217 83 245 3.53E-40 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWM22_RS10440 b6ed50baaed3f7f1f232c37ebfd2094f 246 Gene3D G3DSA:3.30.1330.30 3 94 7.5E-19 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWM22_RS10440 b6ed50baaed3f7f1f232c37ebfd2094f 246 Pfam PF00588 SpoU rRNA Methylase family 104 243 1.0E-34 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CWM22_RS06890 9d97e6783d1b4e7cfbfd2ac2222cbe2e 193 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 171 184 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CWM22_RS06890 9d97e6783d1b4e7cfbfd2ac2222cbe2e 193 Pfam PF00265 Thymidine kinase 3 184 6.2E-48 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CWM22_RS06890 9d97e6783d1b4e7cfbfd2ac2222cbe2e 193 Gene3D G3DSA:3.30.60.20 140 191 2.8E-19 T 28-03-2018 CWM22_RS06890 9d97e6783d1b4e7cfbfd2ac2222cbe2e 193 Gene3D G3DSA:3.40.50.300 2 139 3.5E-42 T 28-03-2018 CWM22_RS06890 9d97e6783d1b4e7cfbfd2ac2222cbe2e 193 SUPERFAMILY SSF52540 2 139 2.28E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06890 9d97e6783d1b4e7cfbfd2ac2222cbe2e 193 Hamap MF_00124 Thymidine kinase [tdk]. 1 187 33.959 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CWM22_RS06890 9d97e6783d1b4e7cfbfd2ac2222cbe2e 193 PIRSF PIRSF035805 1 192 9.4E-58 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CWM22_RS06890 9d97e6783d1b4e7cfbfd2ac2222cbe2e 193 SUPERFAMILY SSF57716 140 190 6.18E-17 T 28-03-2018 CWM22_RS07730 5dc8bce98067386158c3f0bb19703ac4 224 Gene3D G3DSA:3.20.20.70 1 224 3.9E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS07730 5dc8bce98067386158c3f0bb19703ac4 224 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 2 218 8.9E-44 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWM22_RS07730 5dc8bce98067386158c3f0bb19703ac4 224 Pfam PF01487 Type I 3-dehydroquinase 5 218 4.1E-53 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWM22_RS07730 5dc8bce98067386158c3f0bb19703ac4 224 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 2 222 35.854 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWM22_RS07730 5dc8bce98067386158c3f0bb19703ac4 224 SUPERFAMILY SSF51569 1 222 8.79E-62 T 28-03-2018 CWM22_RS03285 156b589ab9efe4b053238542dbf73793 157 SUPERFAMILY SSF88697 3 155 8.95E-49 T 28-03-2018 IPR015947 PUA-like domain CWM22_RS03285 156b589ab9efe4b053238542dbf73793 157 PIRSF PIRSF021320 1 156 1.8E-48 T 28-03-2018 IPR009326 Protein of unknown function DUF984 CWM22_RS03285 156b589ab9efe4b053238542dbf73793 157 SMART SM01022 24 154 2.0E-42 T 28-03-2018 IPR007374 ASCH domain CWM22_RS03285 156b589ab9efe4b053238542dbf73793 157 Gene3D G3DSA:3.10.400.10 2 156 2.4E-59 T 28-03-2018 CWM22_RS03285 156b589ab9efe4b053238542dbf73793 157 Pfam PF04266 ASCH domain 24 154 1.4E-33 T 28-03-2018 IPR007374 ASCH domain CWM22_RS05545 0e305dc84aaa42119665b734edbd506b 71 Gene3D G3DSA:1.10.1220.10 29 65 6.1E-18 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWM22_RS05545 0e305dc84aaa42119665b734edbd506b 71 SUPERFAMILY SSF47598 24 71 2.59E-25 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CWM22_RS05545 0e305dc84aaa42119665b734edbd506b 71 Pfam PF07764 Omega Transcriptional Repressor 2 71 1.6E-47 T 28-03-2018 IPR011686 Omega transcriptional repressor CWM22_RS05670 0e305dc84aaa42119665b734edbd506b 71 Gene3D G3DSA:1.10.1220.10 29 65 6.1E-18 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWM22_RS05670 0e305dc84aaa42119665b734edbd506b 71 SUPERFAMILY SSF47598 24 71 2.59E-25 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CWM22_RS05670 0e305dc84aaa42119665b734edbd506b 71 Pfam PF07764 Omega Transcriptional Repressor 2 71 1.6E-47 T 28-03-2018 IPR011686 Omega transcriptional repressor CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 SMART SM00863 656 699 4.0E-22 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 872 167.255 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 Gene3D G3DSA:3.30.930.10 3 245 7.3E-84 T 28-03-2018 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 855 3.5E-286 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 Gene3D G3DSA:3.30.980.10 557 716 4.1E-45 T 28-03-2018 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 Pfam PF02272 DHHA1 domain 736 870 3.8E-23 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 Pfam PF01411 tRNA synthetases class II (A) 8 559 2.6E-177 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 SUPERFAMILY SSF50447 463 555 1.06E-13 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 656 698 1.1E-19 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 SUPERFAMILY SSF55681 5 248 1.34E-78 T 28-03-2018 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 SUPERFAMILY SSF101353 249 441 3.27E-62 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 SUPERFAMILY SSF55186 555 707 2.22E-52 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 1.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 1.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 1.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWM22_RS08400 3fe66027c631530eb713ecda67631b60 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 1.9E-28 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 19 29 8.1E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 9 19 8.1E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 SMART SM00354 7 77 1.5E-37 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 Gene3D G3DSA:3.40.50.2300 61 180 7.8E-30 T 28-03-2018 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 2.0E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 10 28 - T 28-03-2018 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 Pfam PF13377 Periplasmic binding protein-like domain 176 333 1.5E-26 T 28-03-2018 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 TIGRFAM TIGR01481 ccpA: catabolite control protein A 6 334 7.4E-166 T 28-03-2018 IPR006377 Catabolite control protein A GO:0006355 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 SUPERFAMILY SSF47413 7 65 1.31E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 Gene3D G3DSA:1.10.260.40 8 60 1.2E-24 T 28-03-2018 CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 SUPERFAMILY SSF53822 67 334 6.09E-72 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS09225 816fe95fd25ede483a147fbe7720d022 334 Gene3D G3DSA:3.40.50.2300 181 316 5.0E-32 T 28-03-2018 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 Gene3D G3DSA:3.30.300.10 144 245 6.6E-50 T 28-03-2018 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 245 384 2.9E-68 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 SUPERFAMILY SSF55973 124 244 9.42E-53 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 271 279 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 PIRSF PIRSF000497 1 396 8.2E-174 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 5.3E-38 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 127 137 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 Gene3D G3DSA:3.30.300.10 12 143 9.2E-40 T 28-03-2018 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 395 56.791 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 SUPERFAMILY SSF55973 245 394 1.58E-67 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 SUPERFAMILY SSF55973 5 110 1.81E-42 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 Gene3D G3DSA:3.30.300.10 258 397 1.8E-46 T 28-03-2018 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 Pfam PF02772 S-adenosylmethionine synthetase, central domain 126 243 2.0E-49 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS03105 61be022a64e8e6b7761c8cdcb4cc81dc 399 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 394 1.3E-177 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 SUPERFAMILY SSF46785 1 103 5.16E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 Gene3D G3DSA:1.10.10.10 1 83 5.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 SUPERFAMILY SSF53850 88 288 9.05E-29 T 28-03-2018 CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 Gene3D G3DSA:3.40.190.10 176 261 1.5E-8 T 28-03-2018 CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 Gene3D G3DSA:3.40.190.10 87 175 2.0E-15 T 28-03-2018 CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 Pfam PF03466 LysR substrate binding domain 88 285 2.7E-27 T 28-03-2018 IPR005119 LysR, substrate-binding CWM22_RS09350 438095bcca3020c3751e19d752fa1eb4 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.3E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 Gene3D G3DSA:2.70.70.10 469 629 2.5E-57 T 28-03-2018 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 483 603 5.8E-43 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 SUPERFAMILY SSF55604 5 79 3.27E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 482 606 1.5E-49 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 Pfam PF02378 Phosphotransferase system, EIIC 109 392 5.3E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 Pfam PF00367 phosphotransferase system, EIIB 8 41 4.6E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 545 557 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 SUPERFAMILY SSF51261 479 625 4.97E-52 T 28-03-2018 IPR011055 Duplicated hybrid motif CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 Gene3D G3DSA:3.30.1360.60 4 80 2.7E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 447 1.0E-169 T 28-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 CWM22_RS11000 cd80d17d08c246b5e685689254a5fbba 629 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 Gene3D G3DSA:3.20.20.10 28 263 2.3E-43 T 28-03-2018 IPR029066 PLP-binding barrel CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 294 312 1.8E-9 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 153 162 1.8E-9 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 70 87 1.8E-9 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 375 397 1.8E-9 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 278 365 1.5E-19 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 31 276 3.5E-28 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 SUPERFAMILY SSF50621 252 406 9.84E-45 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 Gene3D G3DSA:2.40.37.10 264 409 1.1E-37 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 267 286 7.0E-12 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 72 84 7.0E-12 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 365 378 7.0E-12 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 52 70 7.0E-12 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWM22_RS10420 42ccdc289ad72b39465ccb8ad8668943 415 SUPERFAMILY SSF51419 20 279 7.69E-57 T 28-03-2018 IPR029066 PLP-binding barrel CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 SMART SM00382 109 259 5.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 Pfam PF06689 ClpX C4-type zinc finger 11 47 1.3E-17 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 Gene3D G3DSA:1.10.8.60 311 402 6.8E-34 T 28-03-2018 CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 304 2.3E-47 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 3 408 50.855 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 SMART SM00994 9 48 1.2E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 9.1E-19 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 4 405 9.6E-191 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 Gene3D G3DSA:3.40.50.300 54 309 5.6E-68 T 28-03-2018 CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 SMART SM01086 311 403 9.0E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 SUPERFAMILY SSF57716 10 45 2.0E-11 T 28-03-2018 CWM22_RS06925 5f1d08f4d7faf02722fd965df099f7f1 408 SUPERFAMILY SSF52540 59 390 2.7E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 SUPERFAMILY SSF52402 191 410 1.85E-59 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 Gene3D G3DSA:3.30.300.10 392 516 1.9E-51 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 PRINTS PR00097 Anthranilate synthase component II signature 171 184 5.5E-6 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 PRINTS PR00097 Anthranilate synthase component II signature 80 91 5.5E-6 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 PRINTS PR00097 Anthranilate synthase component II signature 53 62 5.5E-6 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 Pfam PF00117 Glutamine amidotransferase class-I 11 192 9.6E-42 T 28-03-2018 IPR017926 Glutamine amidotransferase CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 198 1.8E-73 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 2.1E-6 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 2.1E-6 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 2.1E-6 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 Pfam PF02540 NAD synthase 211 254 5.0E-8 T 28-03-2018 IPR022310 NAD/GMP synthase CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 516 54.155 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 SUPERFAMILY SSF52317 4 231 9.72E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 Gene3D G3DSA:3.40.50.620 215 391 2.1E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 SUPERFAMILY SSF54810 396 516 5.23E-50 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 206 516 4.3E-153 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 Gene3D G3DSA:3.40.50.880 4 214 7.4E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 1.1E-7 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 171 184 1.1E-7 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 1.1E-7 T 28-03-2018 CWM22_RS06740 cc7efe72d6a85a716cfcedc8186f358b 516 Pfam PF00958 GMP synthase C terminal domain 424 515 1.5E-43 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 PIRSF PIRSF000185 23 448 1.8E-121 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 SUPERFAMILY SSF51735 203 447 1.39E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 58 186 1.2E-51 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 Gene3D G3DSA:3.40.50.720 210 373 2.3E-44 T 28-03-2018 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 123 136 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 SUPERFAMILY SSF53223 7 197 2.21E-73 T 28-03-2018 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 236 256 4.2E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 115 129 4.2E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 194 216 4.2E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 4.2E-32 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 Gene3D G3DSA:1.10.285.10 374 448 1.8E-26 T 28-03-2018 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 Gene3D G3DSA:1.10.285.10 7 61 1.3E-6 T 28-03-2018 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 203 446 2.2E-87 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 SMART SM00839 205 446 2.9E-86 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWM22_RS01505 065f84ec1f96df8f90f1e8a4a1a78ec9 448 Gene3D G3DSA:3.40.50.10860 62 190 1.0E-54 T 28-03-2018 CWM22_RS06885 6504945aaedf7c5cfcf3a5ac81ab71e8 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 358 1.1E-156 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CWM22_RS06885 6504945aaedf7c5cfcf3a5ac81ab71e8 359 Pfam PF03462 PCRF domain 11 205 3.2E-71 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CWM22_RS06885 6504945aaedf7c5cfcf3a5ac81ab71e8 359 Pfam PF00472 RF-1 domain 213 322 9.3E-38 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CWM22_RS06885 6504945aaedf7c5cfcf3a5ac81ab71e8 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 358 38.993 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CWM22_RS06885 6504945aaedf7c5cfcf3a5ac81ab71e8 359 Gene3D G3DSA:3.30.160.20 211 296 4.7E-27 T 28-03-2018 CWM22_RS06885 6504945aaedf7c5cfcf3a5ac81ab71e8 359 SUPERFAMILY SSF75620 10 354 3.66E-126 T 28-03-2018 CWM22_RS06885 6504945aaedf7c5cfcf3a5ac81ab71e8 359 SMART SM00937 65 180 5.6E-60 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CWM22_RS06885 6504945aaedf7c5cfcf3a5ac81ab71e8 359 Gene3D G3DSA:1.20.58.410 2 97 6.5E-16 T 28-03-2018 CWM22_RS06885 6504945aaedf7c5cfcf3a5ac81ab71e8 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 Pfam PF08363 Glucan-binding protein C 370 434 1.7E-10 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 Pfam PF08363 Glucan-binding protein C 434 630 4.7E-64 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 Gene3D G3DSA:2.60.40.740 1070 1245 0.0035 T 28-03-2018 CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 Gene3D G3DSA:2.60.40.740 1248 1419 0.015 T 28-03-2018 CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 Gene3D G3DSA:2.60.40.740 1426 1586 1.3E-4 T 28-03-2018 CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 Gene3D G3DSA:2.60.40.740 894 1069 0.32 T 28-03-2018 CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 Pfam PF16364 Cell surface antigen C-terminus 1410 1571 8.4E-61 T 28-03-2018 IPR032300 Cell surface antigen, C-terminal CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 TIGRFAM TIGR03726 strep_RK_lipo: putative cross-wall-targeting lipoprotein signal 19 54 1.2E-15 T 28-03-2018 IPR021197 Cross-wall-targeting lipoprotein motif CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 1237 1410 1.6E-62 T 28-03-2018 IPR026345 Adhesin isopeptide-forming adherence domain CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 883 1055 3.2E-56 T 28-03-2018 IPR026345 Adhesin isopeptide-forming adherence domain CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 1060 1233 2.4E-63 T 28-03-2018 IPR026345 Adhesin isopeptide-forming adherence domain CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 SUPERFAMILY SSF74914 346 648 7.32E-78 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1600 1628 1.3E-4 T 28-03-2018 CWM22_RS05615 b77ffbe365235f144496718c47dbb1a8 1631 Gene3D G3DSA:2.60.40.740 727 879 2.7E-4 T 28-03-2018 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 329 1.1E-123 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 327 2.8E-55 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 Gene3D G3DSA:3.40.50.1370 162 331 2.2E-53 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 330 81.187 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 SUPERFAMILY SSF53671 5 331 7.86E-102 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 3.4E-44 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 294 317 6.2E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 6.2E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 6.2E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 6.2E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 Gene3D G3DSA:3.40.50.1370 6 161 4.0E-54 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 9.6E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 9.6E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 308 319 9.6E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 9.6E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS03725 509d95812b6598eee91788845390a6f5 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 9.6E-28 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS11885 e6edde56545518877a23f4aeb59bf6aa 107 Pfam PF02699 Preprotein translocase subunit 6 76 4.7E-22 T 28-03-2018 IPR003849 Preprotein translocase YajC CWM22_RS11885 e6edde56545518877a23f4aeb59bf6aa 107 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 78 3.9E-17 T 28-03-2018 IPR003849 Preprotein translocase YajC CWM22_RS11885 e6edde56545518877a23f4aeb59bf6aa 107 SMART SM01323 2 79 3.5E-25 T 28-03-2018 IPR003849 Preprotein translocase YajC CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 Gene3D G3DSA:3.40.50.300 236 433 6.7E-29 T 28-03-2018 CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 SMART SM00487 256 452 7.8E-23 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 795 24.545 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 Pfam PF04851 Type III restriction enzyme, res subunit 259 422 5.2E-19 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 SMART SM00490 558 655 2.5E-11 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 SUPERFAMILY SSF52540 190 441 2.72E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 Gene3D G3DSA:3.40.50.300 456 696 1.4E-22 T 28-03-2018 CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 TIGRFAM TIGR00595 priA: primosomal protein N' 283 792 7.1E-201 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 Pfam PF00271 Helicase conserved C-terminal domain 567 654 7.5E-9 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS02480 b649ffd119c1506241e68bf9fd6e664d 796 SUPERFAMILY SSF52540 523 702 1.3E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 SUPERFAMILY SSF52540 94 369 5.06E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 PIRSF PIRSF039088 1 500 2.5E-235 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 91 4.0E-15 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 Gene3D G3DSA:1.20.150.20 372 496 1.8E-48 T 28-03-2018 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 498 49.021 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 Gene3D G3DSA:2.40.30.20 2 81 2.7E-32 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 370 493 6.9E-46 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 2 496 5.0E-244 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 SUPERFAMILY SSF50615 10 93 6.28E-27 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 SUPERFAMILY SSF47917 371 496 1.44E-46 T 28-03-2018 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 148 363 1.2E-70 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWM22_RS08170 617e5d9a1e23f7c8fe8275eb08aa302f 500 Gene3D G3DSA:3.40.50.300 82 363 2.9E-114 T 28-03-2018 CWM22_RS04765 0df16ae7b2d74c79874bf4f7131c1ed7 337 SUPERFAMILY SSF51735 1 336 1.46E-96 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS04765 0df16ae7b2d74c79874bf4f7131c1ed7 337 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 334 2.6E-138 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CWM22_RS04765 0df16ae7b2d74c79874bf4f7131c1ed7 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 5.8E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS04765 0df16ae7b2d74c79874bf4f7131c1ed7 337 Gene3D G3DSA:3.40.50.720 1 206 1.9E-38 T 28-03-2018 CWM22_RS04765 0df16ae7b2d74c79874bf4f7131c1ed7 337 Gene3D G3DSA:3.90.25.10 251 336 3.2E-26 T 28-03-2018 CWM22_RS04765 0df16ae7b2d74c79874bf4f7131c1ed7 337 Gene3D G3DSA:3.90.25.10 207 250 3.9E-9 T 28-03-2018 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 SUPERFAMILY SSF52335 936 1053 7.98E-27 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Gene3D G3DSA:3.40.50.20 532 647 4.8E-59 T 28-03-2018 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Gene3D G3DSA:3.30.470.20 749 946 3.8E-40 T 28-03-2018 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.7E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.7E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.7E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.7E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.7E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.7E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.7E-62 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Gene3D G3DSA:1.10.1030.10 401 531 3.4E-51 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 SMART SM00851 949 1037 1.9E-22 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 SMART SM01209 674 837 0.0012 T 28-03-2018 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Pfam PF02142 MGS-like domain 950 1037 6.0E-15 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 SUPERFAMILY SSF52440 1 127 5.61E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Gene3D G3DSA:3.30.470.20 120 400 1.7E-62 T 28-03-2018 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Gene3D G3DSA:3.40.50.1380 947 1056 3.2E-28 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 3.8E-42 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 867 6.9E-38 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 3.1E-77 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 SUPERFAMILY SSF52440 550 668 1.58E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1048 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 SUPERFAMILY SSF56059 128 399 6.19E-106 T 28-03-2018 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Gene3D G3DSA:3.40.50.20 4 117 3.2E-38 T 28-03-2018 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1058 13.112 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 SUPERFAMILY SSF56059 666 927 1.64E-102 T 28-03-2018 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1057 13.284 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 SMART SM01096 420 540 1.4E-70 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 Gene3D G3DSA:3.30.1490.20 648 747 5.0E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS07170 21c23115c6439f0607144af73cd82de9 1059 SUPERFAMILY SSF48108 395 547 9.94E-53 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS00060 9083fe864be94e3374e8006bb1d3d70a 426 SUPERFAMILY SSF56601 190 423 2.32E-33 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS00060 9083fe864be94e3374e8006bb1d3d70a 426 Pfam PF13354 Beta-lactamase enzyme family 211 403 5.5E-38 T 28-03-2018 CWM22_RS00060 9083fe864be94e3374e8006bb1d3d70a 426 Gene3D G3DSA:3.40.710.10 182 425 9.9E-16 T 28-03-2018 CWM22_RS00065 a5130f50d917c296f77baf50d5e2d5a8 422 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 20 193 1.1E-49 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWM22_RS00065 a5130f50d917c296f77baf50d5e2d5a8 422 Pfam PF01171 PP-loop family 20 189 1.3E-50 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CWM22_RS00065 a5130f50d917c296f77baf50d5e2d5a8 422 SMART SM00977 346 405 6.4E-10 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWM22_RS00065 a5130f50d917c296f77baf50d5e2d5a8 422 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 6 288 22.286 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWM22_RS00065 a5130f50d917c296f77baf50d5e2d5a8 422 Gene3D G3DSA:3.40.50.620 15 194 9.7E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS00065 a5130f50d917c296f77baf50d5e2d5a8 422 SUPERFAMILY SSF52402 14 214 4.63E-54 T 28-03-2018 CWM22_RS00065 a5130f50d917c296f77baf50d5e2d5a8 422 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 346 390 8.4E-10 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWM22_RS00065 a5130f50d917c296f77baf50d5e2d5a8 422 SUPERFAMILY SSF56037 342 405 3.92E-8 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 356 47.376 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00097 Anthranilate synthase component II signature 215 224 2.5E-7 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00097 Anthranilate synthase component II signature 327 340 2.5E-7 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00097 Anthranilate synthase component II signature 242 253 2.5E-7 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 212 226 4.1E-34 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 276 4.1E-34 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 242 258 4.1E-34 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 173 187 4.1E-34 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 284 295 4.1E-34 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 SUPERFAMILY SSF52021 2 146 7.59E-57 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 SMART SM01097 2 132 1.3E-88 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 130 3.4E-53 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 Gene3D G3DSA:3.40.50.880 177 359 2.8E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 SUPERFAMILY SSF52317 139 354 1.05E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 353 6.8E-146 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 Gene3D G3DSA:3.50.30.20 1 149 2.1E-59 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 Pfam PF00117 Glutamine amidotransferase class-I 175 350 6.5E-48 T 28-03-2018 IPR017926 Glutamine amidotransferase CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 253 4.7E-12 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00096 Glutamine amidotransferase superfamily signature 215 224 4.7E-12 T 28-03-2018 CWM22_RS07175 ced264c5e7dd03f45addc3f5e3115b70 359 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 4.7E-12 T 28-03-2018 CWM22_RS11460 b9984d8d510cb401ef9360cd5937bf05 350 Pfam PF04138 GtrA-like protein 220 339 8.7E-13 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CWM22_RS11460 b9984d8d510cb401ef9360cd5937bf05 350 SUPERFAMILY SSF53448 2 223 1.88E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS11460 b9984d8d510cb401ef9360cd5937bf05 350 Gene3D G3DSA:3.90.550.10 2 230 3.4E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS11460 b9984d8d510cb401ef9360cd5937bf05 350 Pfam PF00535 Glycosyl transferase family 2 4 127 5.6E-16 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 6.2E-72 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 Hamap MF_00235 Adenylate kinase [adk]. 1 210 48.347 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 PRINTS PR00094 Adenylate kinase signature 174 188 7.2E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 PRINTS PR00094 Adenylate kinase signature 4 17 7.2E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 PRINTS PR00094 Adenylate kinase signature 157 172 7.2E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 PRINTS PR00094 Adenylate kinase signature 32 46 7.2E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 PRINTS PR00094 Adenylate kinase signature 82 98 7.2E-31 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 Pfam PF00406 Adenylate kinase 5 187 1.3E-55 T 28-03-2018 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 Gene3D G3DSA:3.40.50.300 1 213 4.6E-55 T 28-03-2018 CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 SUPERFAMILY SSF52540 1 211 4.95E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00600 a5814807b913252586c410ec2c3c153d 213 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWM22_RS04075 69f6c3b8fb54f3be9ad06cbb919a03a1 485 Pfam PF04233 Phage Mu protein F like protein 182 287 4.8E-11 T 28-03-2018 IPR006528 Phage head morphogenesis domain CWM22_RS04075 69f6c3b8fb54f3be9ad06cbb919a03a1 485 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 184 289 2.5E-21 T 28-03-2018 IPR006528 Phage head morphogenesis domain CWM22_RS07515 a0995a0b31dfeb35375a7ff06a4da619 101 Gene3D G3DSA:3.40.50.2300 2 101 1.2E-32 T 28-03-2018 CWM22_RS07515 a0995a0b31dfeb35375a7ff06a4da619 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 5.0E-20 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS07515 a0995a0b31dfeb35375a7ff06a4da619 101 SUPERFAMILY SSF52794 1 100 4.45E-34 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 PIRSF PIRSF039102 1 345 7.1E-103 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 SUPERFAMILY SSF56059 127 336 2.83E-57 T 28-03-2018 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 Gene3D G3DSA:3.40.50.20 1 137 9.9E-37 T 28-03-2018 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 337 38.563 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 Gene3D G3DSA:3.30.470.20 201 346 2.6E-37 T 28-03-2018 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 279 307 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 SUPERFAMILY SSF52440 3 126 1.15E-30 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 94 105 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 Pfam PF01820 D-ala D-ala ligase N-terminus 6 116 1.4E-25 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 Pfam PF07478 D-ala D-ala ligase C-terminus 135 333 6.3E-73 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 Gene3D G3DSA:3.30.1490.20 142 200 1.0E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWM22_RS08880 12ba3b415aa97d94fc5fc5f95748c069 348 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 336 1.7E-99 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS02000 b070231a8605726f83afa98a4c8c827f 149 SUPERFAMILY SSF46785 2 138 2.72E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02000 b070231a8605726f83afa98a4c8c827f 149 Gene3D G3DSA:1.10.10.10 1 149 2.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02000 b070231a8605726f83afa98a4c8c827f 149 Pfam PF02082 Transcriptional regulator 1 81 8.0E-21 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWM22_RS02140 b49e4267446f9ff24a193caaac00902b 183 SUPERFAMILY SSF52499 2 182 1.96E-47 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWM22_RS02140 b49e4267446f9ff24a193caaac00902b 183 Gene3D G3DSA:3.40.50.850 1 183 4.9E-45 T 28-03-2018 CWM22_RS02140 b49e4267446f9ff24a193caaac00902b 183 Pfam PF00857 Isochorismatase family 4 180 1.0E-33 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWM22_RS03510 09721e61711bcf87db6e3261d97b2879 134 SUPERFAMILY SSF46689 23 84 6.16E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS03510 09721e61711bcf87db6e3261d97b2879 134 Gene3D G3DSA:1.10.10.60 61 97 1.5E-9 T 28-03-2018 CWM22_RS03510 09721e61711bcf87db6e3261d97b2879 134 Gene3D G3DSA:1.10.10.60 23 60 1.7E-10 T 28-03-2018 CWM22_RS03510 09721e61711bcf87db6e3261d97b2879 134 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 73 5.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS12205 a1aaa36a1f3a85b94cf797b4ae6a3dfa 260 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CWM22_RS12205 a1aaa36a1f3a85b94cf797b4ae6a3dfa 260 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 4 12 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CWM22_RS12205 a1aaa36a1f3a85b94cf797b4ae6a3dfa 260 Gene3D G3DSA:3.20.20.140 2 260 2.2E-85 T 28-03-2018 CWM22_RS12205 a1aaa36a1f3a85b94cf797b4ae6a3dfa 260 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 4 255 2.0E-80 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CWM22_RS12205 a1aaa36a1f3a85b94cf797b4ae6a3dfa 260 SUPERFAMILY SSF51556 2 257 1.17E-89 T 28-03-2018 IPR032466 Metal-dependent hydrolase CWM22_RS12205 a1aaa36a1f3a85b94cf797b4ae6a3dfa 260 PIRSF PIRSF005902 1 259 1.1E-78 T 28-03-2018 IPR001130 TatD family GO:0016788 CWM22_RS12205 a1aaa36a1f3a85b94cf797b4ae6a3dfa 260 Pfam PF01026 TatD related DNase 5 254 1.1E-76 T 28-03-2018 IPR001130 TatD family GO:0016788 CWM22_RS01070 a3586c4d334853dc6ee59ec6442e2a47 559 SMART SM00849 23 217 1.6E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS01070 a3586c4d334853dc6ee59ec6442e2a47 559 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 12 554 9.0E-197 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CWM22_RS01070 a3586c4d334853dc6ee59ec6442e2a47 559 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 366 394 - T 28-03-2018 IPR001587 Ribonuclease J, conserved site CWM22_RS01070 a3586c4d334853dc6ee59ec6442e2a47 559 Gene3D G3DSA:3.60.15.10 3 450 2.2E-62 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS01070 a3586c4d334853dc6ee59ec6442e2a47 559 Hamap MF_01491 Ribonuclease J [rnj]. 6 557 45.618 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CWM22_RS01070 a3586c4d334853dc6ee59ec6442e2a47 559 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 360 409 1.4E-11 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CWM22_RS01070 a3586c4d334853dc6ee59ec6442e2a47 559 Pfam PF00753 Metallo-beta-lactamase superfamily 21 169 1.1E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS01070 a3586c4d334853dc6ee59ec6442e2a47 559 SUPERFAMILY SSF56281 14 425 6.42E-91 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS01070 a3586c4d334853dc6ee59ec6442e2a47 559 PIRSF PIRSF004803 3 557 1.0E-224 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CWM22_RS11270 c8a8e8a80a9a3279ed0392c98c63796e 98 Pfam PF04296 Protein of unknown function (DUF448) 10 83 4.6E-23 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CWM22_RS11270 c8a8e8a80a9a3279ed0392c98c63796e 98 Gene3D G3DSA:3.30.1230.10 1 98 1.2E-28 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CWM22_RS11270 c8a8e8a80a9a3279ed0392c98c63796e 98 SUPERFAMILY SSF64376 5 96 8.11E-28 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CWM22_RS05015 d5fd66684417d50f3c849b085230118a 133 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 36.186 T 28-03-2018 IPR023731 Regulatory protein Spx GO:0045892 CWM22_RS05015 d5fd66684417d50f3c849b085230118a 133 Pfam PF03960 ArsC family 22 113 1.5E-23 T 28-03-2018 IPR006660 Arsenate reductase-like CWM22_RS05015 d5fd66684417d50f3c849b085230118a 133 Gene3D G3DSA:3.40.30.10 1 131 9.6E-38 T 28-03-2018 CWM22_RS05015 d5fd66684417d50f3c849b085230118a 133 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 1.2E-35 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CWM22_RS05015 d5fd66684417d50f3c849b085230118a 133 SUPERFAMILY SSF52833 1 125 3.82E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS07735 1c055bd37f1f3541c561a8355b9fc375 387 SUPERFAMILY SSF88697 1 67 2.98E-15 T 28-03-2018 IPR015947 PUA-like domain CWM22_RS07735 1c055bd37f1f3541c561a8355b9fc375 387 Gene3D G3DSA:2.30.130.10 2 63 9.7E-11 T 28-03-2018 IPR002478 PUA domain GO:0003723 CWM22_RS07735 1c055bd37f1f3541c561a8355b9fc375 387 SUPERFAMILY SSF53335 74 370 1.49E-62 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS07735 1c055bd37f1f3541c561a8355b9fc375 387 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 162 339 1.0E-30 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CWM22_RS07735 1c055bd37f1f3541c561a8355b9fc375 387 Gene3D G3DSA:3.40.50.150 173 385 5.0E-24 T 28-03-2018 CWM22_RS07735 1c055bd37f1f3541c561a8355b9fc375 387 Gene3D G3DSA:3.30.750.80 67 172 6.2E-22 T 28-03-2018 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 7 804 0.0 T 28-03-2018 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 SUPERFAMILY SSF101904 497 812 1.05E-107 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Gene3D G3DSA:3.90.199.10 32 211 1.0E-82 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 SUPERFAMILY SSF56719 28 484 3.53E-178 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 469 2.0E-159 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 707 754 3.0E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 502 547 2.2E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 658 703 7.2E-14 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 610 654 5.6E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 552 601 6.3E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 758 804 1.9E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 SMART SM00434 9 462 4.5E-283 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Gene3D G3DSA:1.10.268.10 342 484 4.5E-56 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Gene3D G3DSA:2.120.10.90 495 806 8.6E-122 T 28-03-2018 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Gene3D G3DSA:3.30.1360.40 234 330 1.5E-34 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWM22_RS05140 c56dfcdd39dbd7c04066ce098bfa4939 814 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 806 24.668 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWM22_RS13280 8ffa0108f91d3b96ea3826896d89967e 129 Pfam PF12680 SnoaL-like domain 10 114 1.3E-15 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CWM22_RS13280 8ffa0108f91d3b96ea3826896d89967e 129 Gene3D G3DSA:3.10.450.50 1 123 9.6E-20 T 28-03-2018 CWM22_RS13280 8ffa0108f91d3b96ea3826896d89967e 129 SUPERFAMILY SSF54427 1 128 5.49E-25 T 28-03-2018 IPR032710 NTF2-like domain CWM22_RS03750 555a531ea1fc657f5cd2441dba61963d 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 2.0E-138 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWM22_RS03750 555a531ea1fc657f5cd2441dba61963d 342 Gene3D G3DSA:3.40.1780.10 173 342 1.6E-65 T 28-03-2018 CWM22_RS03750 555a531ea1fc657f5cd2441dba61963d 342 Gene3D G3DSA:3.40.1780.10 1 148 1.7E-40 T 28-03-2018 CWM22_RS03750 555a531ea1fc657f5cd2441dba61963d 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.486 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWM22_RS03750 555a531ea1fc657f5cd2441dba61963d 342 SUPERFAMILY SSF111337 1 341 7.06E-138 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWM22_RS03750 555a531ea1fc657f5cd2441dba61963d 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 1.3E-139 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 132 222 2.9E-30 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 SMART SM00898 2 116 8.3E-50 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 115 3.0E-32 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 Gene3D G3DSA:3.20.190.10 2 127 4.1E-38 T 28-03-2018 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 SUPERFAMILY SSF81624 2 141 2.49E-40 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 SUPERFAMILY SSF46946 132 221 3.97E-28 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 SMART SM01232 132 224 7.8E-40 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 272 41.812 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 271 2.0E-102 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 Gene3D G3DSA:1.10.8.50 133 275 9.8E-50 T 28-03-2018 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 SUPERFAMILY SSF57716 220 271 4.56E-16 T 28-03-2018 CWM22_RS09440 afdfe980b64159e0ade90719e20ea6e8 275 Pfam PF06827 Zinc finger found in FPG and IleRS 244 271 3.7E-9 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CWM22_RS08410 e16d1cbbec585c61f92083b3d99c57d3 333 SUPERFAMILY SSF54534 145 241 1.8E-10 T 28-03-2018 CWM22_RS08410 e16d1cbbec585c61f92083b3d99c57d3 333 Hamap MF_01145 Foldase protein PrsA [prsA]. 5 301 20.515 T 28-03-2018 IPR023059 Foldase protein PrsA GO:0003755 CWM22_RS08410 e16d1cbbec585c61f92083b3d99c57d3 333 SUPERFAMILY SSF109998 28 174 4.71E-20 T 28-03-2018 IPR027304 Trigger factor/SurA domain CWM22_RS08410 e16d1cbbec585c61f92083b3d99c57d3 333 Pfam PF13145 PPIC-type PPIASE domain 132 256 1.7E-12 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CWM22_RS08410 e16d1cbbec585c61f92083b3d99c57d3 333 Gene3D G3DSA:3.10.50.40 140 245 1.3E-15 T 28-03-2018 CWM22_RS08410 e16d1cbbec585c61f92083b3d99c57d3 333 Gene3D G3DSA:1.10.4030.10 23 129 7.6E-9 T 28-03-2018 CWM22_RS13305 165754ae03ee1d7e5ab30d56f623be75 222 SUPERFAMILY SSF46894 125 221 1.08E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWM22_RS13305 165754ae03ee1d7e5ab30d56f623be75 222 SUPERFAMILY SSF52172 1 126 2.13E-35 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS13305 165754ae03ee1d7e5ab30d56f623be75 222 Pfam PF00072 Response regulator receiver domain 4 113 4.6E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS13305 165754ae03ee1d7e5ab30d56f623be75 222 SMART SM00862 149 220 7.1E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS13305 165754ae03ee1d7e5ab30d56f623be75 222 Gene3D G3DSA:3.40.50.2300 1 124 2.1E-29 T 28-03-2018 CWM22_RS13305 165754ae03ee1d7e5ab30d56f623be75 222 Gene3D G3DSA:1.10.10.10 125 222 5.5E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS13305 165754ae03ee1d7e5ab30d56f623be75 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 220 1.8E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS13305 165754ae03ee1d7e5ab30d56f623be75 222 SMART SM00448 2 112 7.4E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 SUPERFAMILY SSF48168 22 168 8.24E-42 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 Pfam PF02867 Ribonucleotide reductase, barrel domain 170 698 3.9E-137 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 SUPERFAMILY SSF51998 169 701 2.14E-169 T 28-03-2018 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 Pfam PF08343 Ribonucleotide reductase N-terminal 11 91 2.7E-27 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 11 719 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 94 165 5.0E-11 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 Gene3D G3DSA:3.20.70.20 74 706 2.1E-150 T 28-03-2018 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 96 701 1.6E-148 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 6.7E-23 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 6.7E-23 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 6.7E-23 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 245 264 6.7E-23 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08340 7ed56ed4642d635381f5386f7b2b96cf 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 6.7E-23 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS05085 109c94b9d4802dc2df74764179a0ed54 77 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 77 13.556 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS05085 109c94b9d4802dc2df74764179a0ed54 77 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 76 1.1E-19 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS05085 109c94b9d4802dc2df74764179a0ed54 77 SUPERFAMILY SSF46992 3 76 4.71E-23 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS05085 109c94b9d4802dc2df74764179a0ed54 77 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 76 9.0E-23 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS05085 109c94b9d4802dc2df74764179a0ed54 77 Gene3D G3DSA:1.20.58.110 1 77 1.8E-20 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS05085 109c94b9d4802dc2df74764179a0ed54 77 Pfam PF01649 Ribosomal protein S20 2 76 2.0E-21 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS02025 4c230dcf14283213c5cc31dfe920067e 199 Gene3D G3DSA:2.60.120.200 3 189 3.6E-39 T 28-03-2018 CWM22_RS02025 4c230dcf14283213c5cc31dfe920067e 199 SUPERFAMILY SSF49899 5 187 2.77E-40 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CWM22_RS02025 4c230dcf14283213c5cc31dfe920067e 199 Pfam PF07081 Protein of unknown function (DUF1349) 8 188 9.8E-66 T 28-03-2018 IPR009784 Protein of unknown function DUF1349 CWM22_RS02025 4c230dcf14283213c5cc31dfe920067e 199 PIRSF PIRSF022704 1 196 8.6E-62 T 28-03-2018 IPR015987 Uncharacterised conserved protein UCP022704 CWM22_RS09875 6694682db730c854b39247f6c6246416 156 SMART SM00899 1 71 4.1E-7 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWM22_RS09875 6694682db730c854b39247f6c6246416 156 SMART SM00899 78 150 4.2E-20 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWM22_RS09875 6694682db730c854b39247f6c6246416 156 SUPERFAMILY SSF50037 3 66 8.93E-8 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CWM22_RS09875 6694682db730c854b39247f6c6246416 156 Gene3D G3DSA:2.30.30.90 77 156 6.5E-17 T 28-03-2018 CWM22_RS09875 6694682db730c854b39247f6c6246416 156 SUPERFAMILY SSF50037 81 150 1.69E-19 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CWM22_RS09875 6694682db730c854b39247f6c6246416 156 Pfam PF04023 FeoA domain 79 149 1.8E-14 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWM22_RS09875 6694682db730c854b39247f6c6246416 156 Pfam PF04023 FeoA domain 1 64 6.1E-7 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWM22_RS09875 6694682db730c854b39247f6c6246416 156 Gene3D G3DSA:2.30.30.90 1 76 1.2E-10 T 28-03-2018 CWM22_RS08495 e0cdc7cd406636cc6fade30a0f1886d9 462 Pfam PF13520 Amino acid permease 20 430 3.0E-50 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWM22_RS08495 e0cdc7cd406636cc6fade30a0f1886d9 462 PIRSF PIRSF006060 6 462 2.7E-78 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 153 180 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 SUPERFAMILY SSF52172 1 132 6.69E-31 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 SUPERFAMILY SSF46894 125 199 3.06E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 Pfam PF00072 Response regulator receiver domain 3 114 5.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 Gene3D G3DSA:3.40.50.2300 1 140 2.1E-32 T 28-03-2018 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 153 9.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 169 9.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 181 9.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 SMART SM00421 136 193 2.8E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 Gene3D G3DSA:1.10.10.10 141 199 6.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 138 193 1.8E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS10300 2d9d166a5be4ff63433cf1d0fd8c0c44 200 SMART SM00448 1 114 1.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS01155 4835eabebddc96ab3fb34ad64d9bc739 232 Gene3D G3DSA:3.40.50.300 2 215 1.9E-43 T 28-03-2018 CWM22_RS01155 4835eabebddc96ab3fb34ad64d9bc739 232 SMART SM00382 27 212 1.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS01155 4835eabebddc96ab3fb34ad64d9bc739 232 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS01155 4835eabebddc96ab3fb34ad64d9bc739 232 SUPERFAMILY SSF52540 3 210 3.86E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01155 4835eabebddc96ab3fb34ad64d9bc739 232 Pfam PF00005 ABC transporter 18 159 1.2E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS00975 8a33e720094bfc04d42a075bde0136df 318 Pfam PF06207 Protein of unknown function (DUF1002) 45 277 9.5E-53 T 28-03-2018 IPR009343 Protein of unknown function DUF1002 CWM22_RS01620 0dd17d249b0316dd0c709b84a7d6cb0a 140 TIGRFAM TIGR01118 lacA: galactose-6-phosphate isomerase, LacA subunit 1 139 9.4E-73 T 28-03-2018 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26 CWM22_RS01620 0dd17d249b0316dd0c709b84a7d6cb0a 140 Pfam PF02502 Ribose/Galactose Isomerase 3 136 1.8E-36 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS01620 0dd17d249b0316dd0c709b84a7d6cb0a 140 Gene3D G3DSA:3.40.1400.10 1 140 2.1E-38 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS01620 0dd17d249b0316dd0c709b84a7d6cb0a 140 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 138 1.3E-32 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS01620 0dd17d249b0316dd0c709b84a7d6cb0a 140 SUPERFAMILY SSF89623 1 139 7.06E-43 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS01620 0dd17d249b0316dd0c709b84a7d6cb0a 140 PIRSF PIRSF005384 1 140 1.6E-38 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS01620 0dd17d249b0316dd0c709b84a7d6cb0a 140 Hamap MF_01555 Galactose-6-phosphate isomerase subunit LacA [lacA]. 1 140 38.864 T 28-03-2018 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26 CWM22_RS10315 b02a4983994283fa8e918e0624ac9d77 292 Gene3D G3DSA:3.40.50.300 1 275 5.3E-56 T 28-03-2018 CWM22_RS10315 b02a4983994283fa8e918e0624ac9d77 292 Pfam PF00005 ABC transporter 17 155 1.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS10315 b02a4983994283fa8e918e0624ac9d77 292 SMART SM00382 26 203 1.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS10315 b02a4983994283fa8e918e0624ac9d77 292 SUPERFAMILY SSF52540 2 218 8.88E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10315 b02a4983994283fa8e918e0624ac9d77 292 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05965 deacdada9fa5015efddb94da230c7f89 313 SUPERFAMILY SSF51395 4 303 9.16E-78 T 28-03-2018 CWM22_RS05965 deacdada9fa5015efddb94da230c7f89 313 Pfam PF01180 Dihydroorotate dehydrogenase 5 291 4.4E-85 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWM22_RS05965 deacdada9fa5015efddb94da230c7f89 313 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 5 306 37.778 T 28-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CWM22_RS05965 deacdada9fa5015efddb94da230c7f89 313 Gene3D G3DSA:3.20.20.70 1 310 1.1E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS05965 deacdada9fa5015efddb94da230c7f89 313 PIRSF PIRSF000164 1 303 3.7E-74 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CWM22_RS05965 deacdada9fa5015efddb94da230c7f89 313 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 41 60 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CWM22_RS05965 deacdada9fa5015efddb94da230c7f89 313 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 244 264 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CWM22_RS05965 deacdada9fa5015efddb94da230c7f89 313 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 5 301 1.0E-102 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWM22_RS04325 66c8ad5b73e97be44072dd52e97acd3f 238 SUPERFAMILY SSF117856 4 238 4.19E-76 T 28-03-2018 CWM22_RS04325 66c8ad5b73e97be44072dd52e97acd3f 238 Pfam PF03306 Alpha-acetolactate decarboxylase 6 226 1.2E-73 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CWM22_RS04325 66c8ad5b73e97be44072dd52e97acd3f 238 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 4 238 4.5E-88 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CWM22_RS04325 66c8ad5b73e97be44072dd52e97acd3f 238 Gene3D G3DSA:3.30.1330.80 3 98 5.0E-32 T 28-03-2018 CWM22_RS04325 66c8ad5b73e97be44072dd52e97acd3f 238 Gene3D G3DSA:3.30.1330.80 99 202 6.1E-39 T 28-03-2018 CWM22_RS04325 66c8ad5b73e97be44072dd52e97acd3f 238 PIRSF PIRSF001332 1 238 2.2E-94 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CWM22_RS07945 946ab371670d1435530d6f7528320608 739 SUPERFAMILY SSF64182 58 434 9.55E-119 T 28-03-2018 CWM22_RS07945 946ab371670d1435530d6f7528320608 739 Pfam PF02272 DHHA1 domain 317 432 1.6E-20 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWM22_RS07945 946ab371670d1435530d6f7528320608 739 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 590 735 2.2E-35 T 28-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal CWM22_RS07945 946ab371670d1435530d6f7528320608 739 Gene3D G3DSA:3.90.1640.10 63 277 4.8E-28 T 28-03-2018 CWM22_RS07945 946ab371670d1435530d6f7528320608 739 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 29 556 1.7E-180 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CWM22_RS07945 946ab371670d1435530d6f7528320608 739 Pfam PF01368 DHH family 84 228 1.3E-11 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 Pfam PF00366 Ribosomal protein S17 11 78 1.7E-32 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 5 77 7.0E-36 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 77 5.1E-35 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 6 81 24.364 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 SUPERFAMILY SSF50249 6 83 4.71E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 Gene3D G3DSA:2.40.50.140 6 83 1.4E-31 T 28-03-2018 CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 1.6E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 1.6E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 1.6E-11 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00540 6401c64aa6a90c9fe4ce4c56651f67b4 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 57 69 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 SMART SM00984 403 491 3.9E-13 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 SMART SM00530 12 67 5.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 404 474 1.8E-7 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 Gene3D G3DSA:1.20.5.100 280 300 2.6E-14 T 28-03-2018 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 Gene3D G3DSA:1.10.260.40 2 78 1.4E-16 T 28-03-2018 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 Pfam PF01381 Helix-turn-helix 14 66 3.6E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 278 367 4.8E-26 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 SUPERFAMILY SSF47413 8 71 5.9E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 Gene3D G3DSA:3.40.50.720 80 279 2.2E-45 T 28-03-2018 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 PIRSF PIRSF500134 81 477 1.9E-117 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 PIRSF PIRSF500134 441 492 2.4 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 82 474 5.6E-91 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 82 250 1.3E-30 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 PIRSF PIRSF000124 81 492 5.9E-127 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 Gene3D G3DSA:3.40.50.720 301 483 4.6E-44 T 28-03-2018 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 SUPERFAMILY SSF48179 277 373 8.5E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 SUPERFAMILY SSF52413 396 492 2.35E-24 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS05285 bf1bd106a2f9f99757403c8b6ebd4b37 492 SUPERFAMILY SSF51735 82 280 1.88E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 317 2.7E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 Gene3D G3DSA:3.40.50.720 161 326 1.6E-31 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 SUPERFAMILY SSF55424 335 449 4.81E-35 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 SUPERFAMILY SSF51905 1 370 2.22E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 2 449 9.2E-213 T 28-03-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PIRSF PIRSF000350 1 443 2.6E-82 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 9.7E-32 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 9.7E-32 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 9.7E-32 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.7E-32 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 9.7E-32 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 Gene3D G3DSA:3.50.50.60 1 159 1.8E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 2.2E-64 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 2.2E-64 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 2.2E-64 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 2.2E-64 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.2E-64 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 2.2E-64 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 2.2E-64 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 2.2E-64 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 2.2E-64 T 28-03-2018 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 Gene3D G3DSA:3.30.390.30 327 449 2.2E-36 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS10090 64a0c44cf33bd12d621a3cc23976313e 449 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 448 6.1E-33 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWM22_RS08385 131681bc51400628c858199a437b1e09 184 Pfam PF11667 Putative zincin peptidase 62 166 4.0E-22 T 28-03-2018 IPR021683 Putative zincin peptidase CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 1.0E-189 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 439 34.254 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 Gene3D G3DSA:3.40.50.300 101 298 7.0E-40 T 28-03-2018 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 3.4E-76 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 SUPERFAMILY SSF47446 328 429 1.64E-34 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 SMART SM00962 101 297 8.0E-114 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 Gene3D G3DSA:1.10.260.30 328 432 3.9E-34 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 Gene3D G3DSA:1.20.120.140 1 92 5.0E-30 T 28-03-2018 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 SMART SM00963 2 87 8.7E-32 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 SUPERFAMILY SSF52540 43 355 1.68E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 Pfam PF02978 Signal peptide binding domain 328 427 1.3E-30 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 SMART SM00382 100 408 5.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.5E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS06725 8e10aa20f6e102f1424f1005e3d55c40 524 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 11 153 2.0E-80 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 SUPERFAMILY SSF63411 7 158 4.12E-61 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 Gene3D G3DSA:3.30.1360.80 6 157 4.9E-57 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 7 151 9.8E-55 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 52 70 4.1E-34 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 8 26 4.1E-34 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 120 139 4.1E-34 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 31 49 4.1E-34 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 76 94 4.1E-34 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 4 158 35.553 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02460 49fc3ec3f81b63829ae517f0efb99f86 160 PIRSF PIRSF006160 4 160 4.3E-64 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS10940 cd2c18b46ab77a6ab6e6dc813ed523e1 321 Gene3D G3DSA:3.20.20.70 1 315 1.0E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS10940 cd2c18b46ab77a6ab6e6dc813ed523e1 321 Pfam PF03060 Nitronate monooxygenase 3 302 3.5E-72 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CWM22_RS10940 cd2c18b46ab77a6ab6e6dc813ed523e1 321 TIGRFAM TIGR03151 enACPred_II: putative enoyl-[acyl-carrier-protein] reductase II 2 310 4.5E-153 T 28-03-2018 IPR017569 Enoyl-(acyl-carrier-protein) reductase II, putative CWM22_RS10940 cd2c18b46ab77a6ab6e6dc813ed523e1 321 SUPERFAMILY SSF51412 1 309 2.75E-73 T 28-03-2018 CWM22_RS05905 792f7c9c802786b8dec6893d7fef7faf 524 SMART SM00857 4 157 8.4E-40 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS05905 792f7c9c802786b8dec6893d7fef7faf 524 Pfam PF00239 Resolvase, N terminal domain 6 156 1.9E-24 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS05905 792f7c9c802786b8dec6893d7fef7faf 524 SUPERFAMILY SSF53041 4 157 6.67E-30 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS05905 792f7c9c802786b8dec6893d7fef7faf 524 Pfam PF13408 Recombinase zinc beta ribbon domain 312 367 9.2E-14 T 28-03-2018 IPR025827 Recombinase zinc beta ribbon domain CWM22_RS05905 792f7c9c802786b8dec6893d7fef7faf 524 Pfam PF07508 Recombinase 184 298 3.4E-22 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CWM22_RS05905 792f7c9c802786b8dec6893d7fef7faf 524 Gene3D G3DSA:3.40.50.1390 1 167 3.0E-42 T 28-03-2018 CWM22_RS04350 e173b65ccadda870735f37f492027a67 288 Gene3D G3DSA:1.10.3470.10 1 277 8.2E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS04350 e173b65ccadda870735f37f492027a67 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 269 1.1E-27 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWM22_RS01755 b6e054ea2344988141223700c012583e 427 Pfam PF13393 Histidyl-tRNA synthetase 8 312 1.7E-43 T 28-03-2018 CWM22_RS01755 b6e054ea2344988141223700c012583e 427 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 409 3.3E-156 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CWM22_RS01755 b6e054ea2344988141223700c012583e 427 Gene3D G3DSA:3.40.50.800 326 427 5.0E-18 T 28-03-2018 IPR004154 Anticodon-binding CWM22_RS01755 b6e054ea2344988141223700c012583e 427 SUPERFAMILY SSF52954 328 419 8.83E-22 T 28-03-2018 IPR004154 Anticodon-binding CWM22_RS01755 b6e054ea2344988141223700c012583e 427 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 426 34.189 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CWM22_RS01755 b6e054ea2344988141223700c012583e 427 Gene3D G3DSA:3.30.930.10 1 323 1.0E-75 T 28-03-2018 CWM22_RS01755 b6e054ea2344988141223700c012583e 427 PIRSF PIRSF001549 1 420 2.5E-122 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CWM22_RS01755 b6e054ea2344988141223700c012583e 427 SUPERFAMILY SSF55681 3 320 2.3E-101 T 28-03-2018 CWM22_RS01755 b6e054ea2344988141223700c012583e 427 Pfam PF03129 Anticodon binding domain 330 415 1.7E-11 T 28-03-2018 IPR004154 Anticodon-binding CWM22_RS12415 a2f232ddcb7b89470618907937aa5d3f 568 Gene3D G3DSA:1.20.1560.10 1 312 5.3E-57 T 28-03-2018 CWM22_RS12415 a2f232ddcb7b89470618907937aa5d3f 568 SUPERFAMILY SSF52540 322 563 3.48E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12415 a2f232ddcb7b89470618907937aa5d3f 568 Pfam PF00664 ABC transporter transmembrane region 16 282 1.1E-34 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS12415 a2f232ddcb7b89470618907937aa5d3f 568 SUPERFAMILY SSF90123 5 311 1.44E-58 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS12415 a2f232ddcb7b89470618907937aa5d3f 568 Pfam PF00005 ABC transporter 344 493 3.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS12415 a2f232ddcb7b89470618907937aa5d3f 568 SMART SM00382 353 539 4.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS12415 a2f232ddcb7b89470618907937aa5d3f 568 ProSitePatterns PS00211 ABC transporters family signature. 465 479 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS12415 a2f232ddcb7b89470618907937aa5d3f 568 Gene3D G3DSA:3.40.50.300 313 568 3.2E-69 T 28-03-2018 CWM22_RS08345 452e98c5d3a4befaadfb918a285593f7 319 PIRSF PIRSF000355 1 314 5.1E-73 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08345 452e98c5d3a4befaadfb918a285593f7 319 SUPERFAMILY SSF47240 2 315 6.12E-99 T 28-03-2018 IPR009078 Ferritin-like superfamily CWM22_RS08345 452e98c5d3a4befaadfb918a285593f7 319 Pfam PF00268 Ribonucleotide reductase, small chain 8 279 9.9E-86 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWM22_RS08345 452e98c5d3a4befaadfb918a285593f7 319 Gene3D G3DSA:1.10.620.20 4 291 1.3E-75 T 28-03-2018 CWM22_RS08345 452e98c5d3a4befaadfb918a285593f7 319 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 5 315 4.0E-150 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWM22_RS04500 0caed26bac59453a380924b76a5cc0b4 79 Gene3D G3DSA:1.10.10.60 15 71 6.8E-6 T 28-03-2018 CWM22_RS08505 5db2ced61e4520350e4a0c0c22873355 275 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 273 4.4E-83 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CWM22_RS08505 5db2ced61e4520350e4a0c0c22873355 275 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 37 46 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CWM22_RS08505 5db2ced61e4520350e4a0c0c22873355 275 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 234 245 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 CWM22_RS08505 5db2ced61e4520350e4a0c0c22873355 275 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 207 223 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 CWM22_RS08505 5db2ced61e4520350e4a0c0c22873355 275 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 273 8.7E-56 T 28-03-2018 CWM22_RS08505 5db2ced61e4520350e4a0c0c22873355 275 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 251 2.7E-16 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWM22_RS08505 5db2ced61e4520350e4a0c0c22873355 275 SUPERFAMILY SSF56219 1 274 2.75E-56 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWM22_RS08505 5db2ced61e4520350e4a0c0c22873355 275 Gene3D G3DSA:3.60.10.10 1 275 9.1E-37 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 256 268 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 252 279 1.0E-88 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 1.0E-88 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 1.0E-88 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 360 382 1.0E-88 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 169 197 1.0E-88 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 1.0E-88 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 SMART SM01350 180 471 1.0E-222 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 175 1.6E-48 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 Gene3D G3DSA:1.20.5.320 439 472 5.1E-19 T 28-03-2018 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 180 470 5.6E-133 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 SUPERFAMILY SSF48179 178 473 2.89E-133 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 SUPERFAMILY SSF51735 4 166 3.05E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 Gene3D G3DSA:3.40.50.720 1 181 4.4E-33 T 28-03-2018 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 Gene3D G3DSA:1.10.1040.10 182 438 4.4E-111 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 471 1.3E-216 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS10550 f333fcaaf521ea54848c2c841c4dfe1d 475 PIRSF PIRSF000109 1 475 2.1E-236 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWM22_RS03390 259e5d869501fe7daf7cbe665f8694cd 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.414 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CWM22_RS03390 259e5d869501fe7daf7cbe665f8694cd 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS03390 259e5d869501fe7daf7cbe665f8694cd 229 Gene3D G3DSA:3.40.50.790 68 148 4.7E-37 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CWM22_RS03390 259e5d869501fe7daf7cbe665f8694cd 229 Gene3D G3DSA:3.30.190.20 149 228 1.6E-18 T 28-03-2018 CWM22_RS03390 259e5d869501fe7daf7cbe665f8694cd 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 1.4E-101 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CWM22_RS03390 259e5d869501fe7daf7cbe665f8694cd 229 SUPERFAMILY SSF56808 6 227 1.31E-82 T 28-03-2018 IPR023674 Ribosomal protein L1-like CWM22_RS03390 259e5d869501fe7daf7cbe665f8694cd 229 PIRSF PIRSF002155 1 227 7.9E-77 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS03390 259e5d869501fe7daf7cbe665f8694cd 229 Pfam PF00687 Ribosomal protein L1p/L10e family 33 220 1.5E-51 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CWM22_RS08595 c15f8515c90857af7bac9acb500b9f46 212 Gene3D G3DSA:3.40.50.300 1 211 9.5E-56 T 28-03-2018 CWM22_RS08595 c15f8515c90857af7bac9acb500b9f46 212 ProSitePatterns PS01331 Thymidylate kinase signature. 94 106 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWM22_RS08595 c15f8515c90857af7bac9acb500b9f46 212 SUPERFAMILY SSF52540 1 208 9.81E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08595 c15f8515c90857af7bac9acb500b9f46 212 Hamap MF_00165 Thymidylate kinase [tmk]. 5 208 31.478 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWM22_RS08595 c15f8515c90857af7bac9acb500b9f46 212 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 198 6.5E-61 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWM22_RS08595 c15f8515c90857af7bac9acb500b9f46 212 Pfam PF02223 Thymidylate kinase 9 199 2.6E-52 T 28-03-2018 CWM22_RS02410 8cd5f9d9054de6602ce4676b18d9046d 67 PRINTS PR00050 Cold shock protein signature 4 19 1.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWM22_RS02410 8cd5f9d9054de6602ce4676b18d9046d 67 PRINTS PR00050 Cold shock protein signature 24 33 1.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWM22_RS02410 8cd5f9d9054de6602ce4676b18d9046d 67 PRINTS PR00050 Cold shock protein signature 39 57 1.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWM22_RS02410 8cd5f9d9054de6602ce4676b18d9046d 67 Gene3D G3DSA:2.40.50.140 1 66 1.7E-28 T 28-03-2018 CWM22_RS02410 8cd5f9d9054de6602ce4676b18d9046d 67 Pfam PF00313 'Cold-shock' DNA-binding domain 2 65 1.1E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWM22_RS02410 8cd5f9d9054de6602ce4676b18d9046d 67 SUPERFAMILY SSF50249 1 66 1.41E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS02410 8cd5f9d9054de6602ce4676b18d9046d 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CWM22_RS02410 8cd5f9d9054de6602ce4676b18d9046d 67 PIRSF PIRSF002599 1 67 4.4E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CWM22_RS02410 8cd5f9d9054de6602ce4676b18d9046d 67 SMART SM00357 3 66 3.3E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CWM22_RS02880 583f73b5fcd4f6b0e43e66dcdc9a9207 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS02880 583f73b5fcd4f6b0e43e66dcdc9a9207 244 PIRSF PIRSF039085 2 244 9.4E-118 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CWM22_RS02880 583f73b5fcd4f6b0e43e66dcdc9a9207 244 Gene3D G3DSA:3.40.50.300 2 244 1.9E-82 T 28-03-2018 CWM22_RS02880 583f73b5fcd4f6b0e43e66dcdc9a9207 244 SUPERFAMILY SSF52540 5 239 2.13E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02880 583f73b5fcd4f6b0e43e66dcdc9a9207 244 SMART SM00382 30 217 2.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS02880 583f73b5fcd4f6b0e43e66dcdc9a9207 244 Pfam PF00005 ABC transporter 21 169 3.2E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS07915 d0d72dbfa657379697bb6bbd5529f734 264 Gene3D G3DSA:3.40.1390.30 1 113 6.9E-31 T 28-03-2018 CWM22_RS07915 d0d72dbfa657379697bb6bbd5529f734 264 SUPERFAMILY SSF102705 1 263 1.29E-83 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWM22_RS07915 d0d72dbfa657379697bb6bbd5529f734 264 Gene3D G3DSA:3.40.1390.30 114 226 3.2E-35 T 28-03-2018 CWM22_RS07915 d0d72dbfa657379697bb6bbd5529f734 264 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 241 1.2E-70 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWM22_RS07915 d0d72dbfa657379697bb6bbd5529f734 264 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 3 250 4.9E-62 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWM22_RS05850 4e12fb3825ae48a9c7119e4a8ab44543 230 Gene3D G3DSA:3.40.50.300 2 219 1.6E-60 T 28-03-2018 CWM22_RS05850 4e12fb3825ae48a9c7119e4a8ab44543 230 Pfam PF00005 ABC transporter 18 156 5.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05850 4e12fb3825ae48a9c7119e4a8ab44543 230 SUPERFAMILY SSF52540 3 207 4.51E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05850 4e12fb3825ae48a9c7119e4a8ab44543 230 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05850 4e12fb3825ae48a9c7119e4a8ab44543 230 SMART SM00382 27 203 1.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 SMART SM01400 10 126 2.1E-77 T 28-03-2018 CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 6.7E-105 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 317 44.247 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 SUPERFAMILY SSF53271 112 307 9.55E-43 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 Gene3D G3DSA:3.40.50.2020 7 162 1.9E-69 T 28-03-2018 CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 7.0E-49 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 Gene3D G3DSA:3.40.50.2020 163 318 7.2E-33 T 28-03-2018 CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 Pfam PF14572 Phosphoribosyl synthetase-associated domain 212 317 5.9E-23 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWM22_RS05340 36085fecaadc7af5c4ec43dc5d567d19 325 SUPERFAMILY SSF53271 10 163 4.85E-54 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS00755 a617154be1c77f441e8d6665c7e8ee61 479 Pfam PF01580 FtsK/SpoIIIE family 228 399 1.2E-7 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CWM22_RS00755 a617154be1c77f441e8d6665c7e8ee61 479 Gene3D G3DSA:3.40.50.300 226 428 1.2E-11 T 28-03-2018 CWM22_RS00755 a617154be1c77f441e8d6665c7e8ee61 479 SUPERFAMILY SSF52540 230 419 3.94E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 SUPERFAMILY SSF54211 3 228 4.93E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 SUPERFAMILY SSF55060 212 355 9.59E-31 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 PRINTS PR00959 Mevalonate kinase family signature 7 31 5.3E-7 T 28-03-2018 CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 PRINTS PR00959 Mevalonate kinase family signature 314 331 5.3E-7 T 28-03-2018 CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 PRINTS PR00959 Mevalonate kinase family signature 110 132 5.3E-7 T 28-03-2018 CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 Gene3D G3DSA:3.30.230.10 1 218 1.5E-39 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 3 356 9.9E-113 T 28-03-2018 IPR005917 Phosphomevalonate kinase KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922 CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 Gene3D G3DSA:3.30.70.890 219 359 1.4E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 Pfam PF00288 GHMP kinases N terminal domain 102 172 1.2E-10 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWM22_RS01830 2f987b01c15eb61d575ec58f2756563f 359 Pfam PF08544 GHMP kinases C terminal 274 345 3.8E-8 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 Gene3D G3DSA:3.40.1160.10 2 314 4.4E-58 T 28-03-2018 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 TIGRFAM TIGR00746 arcC: carbamate kinase 4 314 1.1E-130 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 Pfam PF00696 Amino acid kinase family 5 294 1.8E-30 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 PIRSF PIRSF000723 2 314 2.3E-121 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 PRINTS PR01469 Bacterial carbamate kinase signature 110 129 7.2E-62 T 28-03-2018 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 PRINTS PR01469 Bacterial carbamate kinase signature 159 178 7.2E-62 T 28-03-2018 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 7.2E-62 T 28-03-2018 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 PRINTS PR01469 Bacterial carbamate kinase signature 182 200 7.2E-62 T 28-03-2018 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 PRINTS PR01469 Bacterial carbamate kinase signature 213 228 7.2E-62 T 28-03-2018 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 7.2E-62 T 28-03-2018 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 PRINTS PR01469 Bacterial carbamate kinase signature 268 283 7.2E-62 T 28-03-2018 CWM22_RS03730 9026920f7ee0356bc444eee3bbaaf452 315 SUPERFAMILY SSF53633 4 312 3.33E-86 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 539 1.2E-46 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 SUPERFAMILY SSF52518 370 562 2.5E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 429 448 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 Gene3D G3DSA:3.40.50.970 351 559 1.8E-46 T 28-03-2018 CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 174 1.6E-56 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 335 2.3E-46 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 11 563 2.6E-233 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 SUPERFAMILY SSF52518 6 190 7.15E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 Gene3D G3DSA:3.40.50.970 5 202 5.3E-60 T 28-03-2018 CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 Gene3D G3DSA:3.40.50.1220 203 350 3.4E-48 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWM22_RS11455 81f1508b85412109635c425ce60311d9 567 SUPERFAMILY SSF52467 193 360 3.08E-58 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWM22_RS02685 240340bb0c722f5aa88e549c473dafb9 333 SUPERFAMILY SSF74650 6 331 1.7E-90 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWM22_RS02685 240340bb0c722f5aa88e549c473dafb9 333 PIRSF PIRSF005096 2 333 3.4E-91 T 28-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CWM22_RS02685 240340bb0c722f5aa88e549c473dafb9 333 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 169 178 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CWM22_RS02685 240340bb0c722f5aa88e549c473dafb9 333 Pfam PF01263 Aldose 1-epimerase 13 330 7.9E-67 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CWM22_RS02685 240340bb0c722f5aa88e549c473dafb9 333 Gene3D G3DSA:2.70.98.10 1 333 1.5E-81 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CWM22_RS10530 134377d95c4fd3a58cb56f08d4f3585a 163 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 82.108 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CWM22_RS10530 134377d95c4fd3a58cb56f08d4f3585a 163 Pfam PF03477 ATP cone domain 50 136 1.5E-20 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CWM22_RS10530 134377d95c4fd3a58cb56f08d4f3585a 163 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 1.9E-57 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CWM22_RS04980 35ad30125fafe44b637534ddd3f9796d 419 Pfam PF09903 Uncharacterized protein conserved in bacteria (DUF2130) 145 403 5.0E-93 T 28-03-2018 IPR019219 Protein of unknown function DUF2130 CWM22_RS04980 35ad30125fafe44b637534ddd3f9796d 419 Gene3D G3DSA:1.20.1330.10 17 403 1.2E-7 T 28-03-2018 CWM22_RS04980 35ad30125fafe44b637534ddd3f9796d 419 PIRSF PIRSF005850 1 417 5.1E-152 T 28-03-2018 IPR019219 Protein of unknown function DUF2130 CWM22_RS11650 7adbbdf48576dba596c3f6e320428c0a 713 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 14 705 4.4E-123 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CWM22_RS11650 7adbbdf48576dba596c3f6e320428c0a 713 Gene3D G3DSA:1.20.1050.60 320 413 1.8E-20 T 28-03-2018 CWM22_RS11650 7adbbdf48576dba596c3f6e320428c0a 713 Gene3D G3DSA:1.20.1610.10 414 585 3.7E-47 T 28-03-2018 CWM22_RS11650 7adbbdf48576dba596c3f6e320428c0a 713 Pfam PF07971 Glycosyl hydrolase family 92 218 704 5.0E-125 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CWM22_RS11650 7adbbdf48576dba596c3f6e320428c0a 713 SUPERFAMILY SSF48208 239 650 6.8E-28 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CWM22_RS11650 7adbbdf48576dba596c3f6e320428c0a 713 Gene3D G3DSA:2.70.98.10 3 295 2.9E-41 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CWM22_RS01240 aeab218df9cb666219b68c7cc91cad0d 429 Gene3D G3DSA:3.90.350.10 123 335 4.4E-25 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS01240 aeab218df9cb666219b68c7cc91cad0d 429 Pfam PF01609 Transposase DDE domain 100 351 2.8E-28 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS01240 aeab218df9cb666219b68c7cc91cad0d 429 SUPERFAMILY SSF53098 99 385 1.14E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS06570 499e6445624d1de50e787abc02745360 232 Gene3D G3DSA:3.40.50.2300 4 128 4.2E-27 T 28-03-2018 CWM22_RS06570 499e6445624d1de50e787abc02745360 232 Gene3D G3DSA:1.10.10.10 129 232 2.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06570 499e6445624d1de50e787abc02745360 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 5.3E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS06570 499e6445624d1de50e787abc02745360 232 SMART SM00448 10 121 8.9E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS06570 499e6445624d1de50e787abc02745360 232 SUPERFAMILY SSF52172 10 182 4.2E-32 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS06570 499e6445624d1de50e787abc02745360 232 Pfam PF00072 Response regulator receiver domain 12 120 4.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS06570 499e6445624d1de50e787abc02745360 232 SMART SM00862 154 230 1.4E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS07550 826b0ada3be7afe0020cbf0f5106603a 169 Gene3D G3DSA:3.40.630.30 1 169 1.8E-33 T 28-03-2018 CWM22_RS07550 826b0ada3be7afe0020cbf0f5106603a 169 SUPERFAMILY SSF55729 1 162 6.98E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS07550 826b0ada3be7afe0020cbf0f5106603a 169 Pfam PF13420 Acetyltransferase (GNAT) domain 4 157 2.5E-37 T 28-03-2018 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 335 47.713 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 Gene3D G3DSA:3.40.50.450 1 199 9.4E-84 T 28-03-2018 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 ProSitePatterns PS00433 Phosphofructokinase signature. 244 262 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 SUPERFAMILY SSF53784 1 300 1.83E-111 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 Pfam PF00365 Phosphofructokinase 3 276 4.8E-109 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 298 2.9E-125 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PIRSF PIRSF000532 1 321 8.7E-120 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 Gene3D G3DSA:3.40.50.450 200 299 3.6E-15 T 28-03-2018 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.0E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 240 262 1.0E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.0E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.0E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.0E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.0E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.0E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.0E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS04840 5b8009d342590a4819b9bc47010a3fb3 336 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.0E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWM22_RS07285 e4dae8e58a23f44d7e1794805574d60f 340 Gene3D G3DSA:3.30.470.10 1 162 3.6E-53 T 28-03-2018 CWM22_RS07285 e4dae8e58a23f44d7e1794805574d60f 340 PIRSF PIRSF006468 2 340 7.0E-119 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CWM22_RS07285 e4dae8e58a23f44d7e1794805574d60f 340 Gene3D G3DSA:3.20.10.10 163 322 1.9E-39 T 28-03-2018 CWM22_RS07285 e4dae8e58a23f44d7e1794805574d60f 340 ProSitePatterns PS00770 Aminotransferases class-IV signature. 220 249 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWM22_RS07285 e4dae8e58a23f44d7e1794805574d60f 340 Pfam PF01063 Amino-transferase class IV 55 293 7.0E-35 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWM22_RS07285 e4dae8e58a23f44d7e1794805574d60f 340 SUPERFAMILY SSF56752 3 336 4.97E-101 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWM22_RS07285 e4dae8e58a23f44d7e1794805574d60f 340 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 30 339 4.1E-135 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 39.009 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 9.9E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 9.9E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 9.9E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 9.9E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 9.9E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 9.9E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 Gene3D G3DSA:2.40.50.140 1 137 1.5E-60 T 28-03-2018 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 2.1E-65 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 Pfam PF00164 Ribosomal protein S12/S23 30 136 1.9E-35 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 SUPERFAMILY SSF50249 2 136 3.17E-46 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS01015 030a7c8fa3bbf02ced7ea6313e3b988f 137 PIRSF PIRSF002133 1 137 1.4E-46 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 7.3E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 7.3E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 7.3E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 7.3E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 7.3E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 1.2E-31 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 SUPERFAMILY SSF46589 1 113 2.3E-30 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 4.4E-176 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 Gene3D G3DSA:1.10.287.40 2 105 9.4E-25 T 28-03-2018 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 399 1.1E-37 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 Gene3D G3DSA:3.30.930.10 106 424 6.8E-106 T 28-03-2018 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 PIRSF PIRSF001529 1 424 9.0E-185 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 42.663 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWM22_RS10845 ed106cba675189f71c9f010e6562c472 424 SUPERFAMILY SSF55681 117 419 1.93E-110 T 28-03-2018 CWM22_RS09865 3f022647827794b8b207b3d3a9243bd4 362 SUPERFAMILY SSF56349 60 341 2.3E-55 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS09865 3f022647827794b8b207b3d3a9243bd4 362 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 60 114 2.3E-7 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWM22_RS09865 3f022647827794b8b207b3d3a9243bd4 362 Gene3D G3DSA:1.10.150.130 55 164 4.8E-13 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWM22_RS09865 3f022647827794b8b207b3d3a9243bd4 362 Pfam PF14657 Arm DNA-binding domain 11 52 1.4E-11 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CWM22_RS09865 3f022647827794b8b207b3d3a9243bd4 362 Gene3D G3DSA:1.10.443.10 165 353 3.4E-35 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS09865 3f022647827794b8b207b3d3a9243bd4 362 Pfam PF00589 Phage integrase family 168 337 1.2E-25 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS06675 41f2cc6fcd17d1d1ed46a91fafbb41e3 250 Gene3D G3DSA:3.40.50.300 1 238 1.4E-62 T 28-03-2018 CWM22_RS06675 41f2cc6fcd17d1d1ed46a91fafbb41e3 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS06675 41f2cc6fcd17d1d1ed46a91fafbb41e3 250 SMART SM00382 33 220 1.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS06675 41f2cc6fcd17d1d1ed46a91fafbb41e3 250 Pfam PF00005 ABC transporter 24 173 6.8E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS06675 41f2cc6fcd17d1d1ed46a91fafbb41e3 250 SUPERFAMILY SSF52540 2 224 1.13E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10665 f3b5d85f4240e28a03b9678d4ed83edc 329 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWM22_RS10665 f3b5d85f4240e28a03b9678d4ed83edc 329 Gene3D G3DSA:1.10.600.10 1 327 1.6E-67 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWM22_RS10665 f3b5d85f4240e28a03b9678d4ed83edc 329 SUPERFAMILY SSF48576 4 322 4.5E-66 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWM22_RS10665 f3b5d85f4240e28a03b9678d4ed83edc 329 Pfam PF00348 Polyprenyl synthetase 36 271 5.1E-52 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CWM22_RS10665 f3b5d85f4240e28a03b9678d4ed83edc 329 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 84 98 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 Pfam PF17191 RecG wedge domain 12 161 1.4E-13 T 28-03-2018 IPR033454 RecG, wedge domain CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 Pfam PF00270 DEAD/DEAH box helicase 255 410 1.6E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 Gene3D G3DSA:1.10.150.20 6 40 0.0015 T 28-03-2018 CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 SUPERFAMILY SSF52540 372 581 8.19E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 SMART SM00490 316 386 0.62 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 SMART SM00490 483 568 1.6E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 Pfam PF00271 Helicase conserved C-terminal domain 454 567 1.2E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 Gene3D G3DSA:3.40.50.300 436 608 1.8E-29 T 28-03-2018 CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 SMART SM00487 250 438 4.7E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 Gene3D G3DSA:3.40.50.300 241 435 1.9E-37 T 28-03-2018 CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 SUPERFAMILY SSF52540 170 431 3.24E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 642 1.0E-239 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 SUPERFAMILY SSF50249 4 163 1.88E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS02100 5a6155676b0ea6b644dea0ec9acf975e 672 Gene3D G3DSA:2.40.50.140 44 129 1.1E-8 T 28-03-2018 CWM22_RS09215 28a4df1112f3088f9dd126c59caac7c9 332 Pfam PF13439 Glycosyltransferase Family 4 43 140 2.7E-15 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CWM22_RS09215 28a4df1112f3088f9dd126c59caac7c9 332 Pfam PF00534 Glycosyl transferases group 1 152 304 1.5E-11 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWM22_RS09215 28a4df1112f3088f9dd126c59caac7c9 332 Gene3D G3DSA:3.40.50.2000 17 149 7.6E-9 T 28-03-2018 CWM22_RS09215 28a4df1112f3088f9dd126c59caac7c9 332 SUPERFAMILY SSF53756 2 330 2.35E-49 T 28-03-2018 CWM22_RS09215 28a4df1112f3088f9dd126c59caac7c9 332 Gene3D G3DSA:3.40.50.2000 150 312 4.3E-24 T 28-03-2018 CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 6.9E-26 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 Gene3D G3DSA:3.40.50.1000 1 24 0.083 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 2.0E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 2.0E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 2.0E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 2.0E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 2.0E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 SUPERFAMILY SSF56784 1 211 1.17E-43 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 Gene3D G3DSA:3.40.50.1000 75 212 1.3E-27 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 182 3.9E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS10965 98d488b104460400954f0a4919d697ee 213 Gene3D G3DSA:1.10.150.240 25 74 3.2E-24 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 SUPERFAMILY SSF74650 393 593 1.69E-60 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 SUPERFAMILY SSF74650 628 873 1.69E-60 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 Gene3D G3DSA:3.20.110.10 1 217 1.1E-48 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 Gene3D G3DSA:2.60.40.1180 383 532 1.4E-13 T 28-03-2018 CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 5 271 1.1E-30 T 28-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 Gene3D G3DSA:1.20.1270.50 295 382 4.3E-17 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 SMART SM00872 297 367 9.6E-18 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 399 857 2.7E-30 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 SUPERFAMILY SSF88688 297 389 2.09E-12 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 Pfam PF09261 Alpha mannosidase middle domain 298 366 1.8E-7 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 CWM22_RS11640 375ecc8add7573414c3b34223e73612c 890 SUPERFAMILY SSF88713 3 272 2.11E-61 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWM22_RS02155 c0c67dc0840763925b73efa56eb79357 100 SUPERFAMILY SSF141000 2 93 3.92E-28 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CWM22_RS02155 c0c67dc0840763925b73efa56eb79357 100 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 24.196 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CWM22_RS02155 c0c67dc0840763925b73efa56eb79357 100 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 4.2E-18 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CWM22_RS02155 c0c67dc0840763925b73efa56eb79357 100 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 7.7E-32 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SUPERFAMILY SSF51126 978 1207 6.63E-6 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07580 M26 IgA1-specific Metallo-endopeptidase C-terminal region 249 973 1.4E-50 T 28-03-2018 IPR011505 Peptidase M26, C-terminal domain GO:0004222|GO:0005576|GO:0005618|GO:0008270 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 1742 1817 1.2E-12 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 1605 1677 4.3E-13 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 1536 1604 1.3E-9 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 1956 2022 8.2E-9 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 1394 1463 1.9E-9 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF04650 YSIRK type signal peptide 2 26 7.8E-7 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 2023 2092 3.9E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 1958 2021 1.4E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 1821 1881 4.8E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 1678 1741 1.2E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 1603 1673 2.7E-8 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 1883 1953 1.9E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 2114 2183 4.6E-11 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 1538 1601 6.3E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 1464 1533 3.8E-8 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 1398 1461 6.0E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Pfam PF07501 G5 domain 1743 1813 1.9E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 2023 2090 2.1E-12 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 1676 1742 4.2E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 1393 1462 2.0E-8 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 1604 1674 3.0E-8 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 2024 2094 8.1E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 1884 1954 3.9E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 1536 1602 5.5E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 1816 1882 4.3E-5 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 1464 1534 2.0E-8 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 1744 1814 3.9E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 1956 2022 1.5E-5 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 SMART SM01208 2107 2185 5.5E-11 T 28-03-2018 IPR011098 G5 domain CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 1678 1741 4.3E-9 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 1818 1881 4.3E-9 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 1882 1954 1.3E-12 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 1464 1534 1.3E-12 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 Gene3D G3DSA:2.20.230.10 2111 2185 1.1E-9 T 28-03-2018 CWM22_RS03860 5693e187c4c14b3fe8bc3e163d483e07 2291 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 2 37 1.5E-7 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS08620 0e6186c60dd184cc085cb05a9779bd36 218 Gene3D G3DSA:3.10.580.10 1 152 4.7E-34 T 28-03-2018 CWM22_RS08620 0e6186c60dd184cc085cb05a9779bd36 218 SMART SM00116 10 57 6.3E-11 T 28-03-2018 IPR000644 CBS domain CWM22_RS08620 0e6186c60dd184cc085cb05a9779bd36 218 SMART SM00116 84 131 7.9E-11 T 28-03-2018 IPR000644 CBS domain CWM22_RS08620 0e6186c60dd184cc085cb05a9779bd36 218 Gene3D G3DSA:3.30.70.260 153 211 2.1E-5 T 28-03-2018 CWM22_RS08620 0e6186c60dd184cc085cb05a9779bd36 218 SUPERFAMILY SSF55021 138 197 4.2E-5 T 28-03-2018 CWM22_RS08620 0e6186c60dd184cc085cb05a9779bd36 218 Pfam PF00571 CBS domain 3 55 2.7E-16 T 28-03-2018 IPR000644 CBS domain CWM22_RS08620 0e6186c60dd184cc085cb05a9779bd36 218 Pfam PF00571 CBS domain 77 131 3.0E-13 T 28-03-2018 IPR000644 CBS domain CWM22_RS08620 0e6186c60dd184cc085cb05a9779bd36 218 SUPERFAMILY SSF54631 1 131 4.01E-36 T 28-03-2018 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 SUPERFAMILY SSF51569 11 291 5.86E-90 T 28-03-2018 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 Gene3D G3DSA:3.20.20.70 8 305 1.3E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 SMART SM01130 8 295 8.3E-114 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 7 293 59.636 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 135 152 3.1E-30 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 3.1E-30 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 3.1E-30 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 110 126 3.1E-30 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 140 170 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 PIRSF PIRSF001365 9 302 1.5E-85 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 11 291 8.9E-91 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS07475 69f1f1f9ac55e1fff4fcaa94c6c1d8c1 311 Pfam PF00701 Dihydrodipicolinate synthetase family 10 288 1.0E-83 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 137 625 7.1E-226 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 Pfam PF06480 FtsH Extracellular 14 129 1.0E-8 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 Gene3D G3DSA:1.10.8.60 374 446 4.6E-25 T 28-03-2018 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 12 639 36.868 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 SMART SM00382 221 360 2.1E-23 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 Gene3D G3DSA:3.40.50.300 165 373 4.9E-62 T 28-03-2018 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 ProSitePatterns PS00674 AAA-protein family signature. 328 346 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 SUPERFAMILY SSF140990 441 630 3.66E-67 T 28-03-2018 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 225 357 8.4E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 Pfam PF01434 Peptidase family M41 420 624 2.8E-77 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CWM22_RS00075 8d8ecc8bbc50546a9bb3e8c4a7f09222 657 SUPERFAMILY SSF52540 183 428 2.47E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07645 a68314c2dec7e1181e3fc3b7b90ac452 266 SUPERFAMILY SSF52540 2 237 2.44E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07645 a68314c2dec7e1181e3fc3b7b90ac452 266 SMART SM00382 34 238 3.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS07645 a68314c2dec7e1181e3fc3b7b90ac452 266 Pfam PF00005 ABC transporter 25 180 9.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS07645 a68314c2dec7e1181e3fc3b7b90ac452 266 Gene3D G3DSA:3.40.50.300 1 258 5.3E-52 T 28-03-2018 CWM22_RS09290 c5db8ac22ee0e7ec01bebfbf40412458 1121 Pfam PF02687 FtsX-like permease family 1021 1111 5.4E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWM22_RS09290 c5db8ac22ee0e7ec01bebfbf40412458 1121 Pfam PF02687 FtsX-like permease family 620 709 2.8E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWM22_RS09290 c5db8ac22ee0e7ec01bebfbf40412458 1121 Pfam PF06696 Streptococcal surface antigen repeat 472 496 1.4E-8 T 28-03-2018 IPR009578 Cell surface antigen repeat CWM22_RS09290 c5db8ac22ee0e7ec01bebfbf40412458 1121 Gene3D G3DSA:1.10.287.620 221 394 1.8E-13 T 28-03-2018 CWM22_RS09290 c5db8ac22ee0e7ec01bebfbf40412458 1121 Gene3D G3DSA:1.20.120.330 395 562 7.1E-9 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 505 511 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 230 811 8.1E-199 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 Pfam PF00403 Heavy-metal-associated domain 76 136 6.2E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 Pfam PF00403 Heavy-metal-associated domain 7 66 2.1E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 SUPERFAMILY SSF55008 2 67 2.09E-20 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00943 Copper-transporting ATPase signature 736 750 4.1E-24 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00943 Copper-transporting ATPase signature 486 501 4.1E-24 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00943 Copper-transporting ATPase signature 272 291 4.1E-24 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00943 Copper-transporting ATPase signature 88 102 4.1E-24 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00943 Copper-transporting ATPase signature 215 234 4.1E-24 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00943 Copper-transporting ATPase signature 425 439 4.1E-24 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00943 Copper-transporting ATPase signature 195 213 4.1E-24 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00943 Copper-transporting ATPase signature 292 310 4.1E-24 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00943 Copper-transporting ATPase signature 679 696 4.1E-24 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 Gene3D G3DSA:3.40.50.1000 628 768 1.7E-43 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 SUPERFAMILY SSF56784 501 521 2.42E-63 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 SUPERFAMILY SSF56784 560 809 2.42E-63 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 Gene3D G3DSA:3.30.70.100 1 69 4.5E-21 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 Gene3D G3DSA:3.40.1110.10 527 627 6.2E-30 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 Gene3D G3DSA:3.30.70.100 72 143 2.8E-21 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 SUPERFAMILY SSF81653 305 402 7.72E-33 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 659 6.1E-27 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 352 366 6.1E-27 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 702 721 6.1E-27 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 503 517 6.1E-27 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 725 737 6.1E-27 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 ProSitePatterns PS01047 Heavy-metal-associated domain. 78 107 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 SUPERFAMILY SSF55008 68 138 6.68E-21 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 Pfam PF00702 haloacid dehalogenase-like hydrolase 499 715 7.2E-49 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 SUPERFAMILY SSF81665 246 306 1.2E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 SUPERFAMILY SSF81665 751 790 1.2E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 SUPERFAMILY SSF81665 403 497 1.2E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 Pfam PF00122 E1-E2 ATPase 303 482 3.4E-60 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 274 779 8.6E-102 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 211 812 2.5E-188 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00942 Copper-transporting ATPase 1 signature 96 117 1.0E-8 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00942 Copper-transporting ATPase 1 signature 3 28 1.0E-8 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 PRINTS PR00942 Copper-transporting ATPase 1 signature 213 238 1.0E-8 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 Gene3D G3DSA:1.20.1110.10 247 526 1.5E-52 T 28-03-2018 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 77 137 3.3E-12 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CWM22_RS09365 62ad2e99db19b2369d7a9aa644346010 818 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 5 67 3.3E-15 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CWM22_RS12300 1170958f889a5ae66b562d820d316067 303 SUPERFAMILY SSF63817 104 245 3.01E-45 T 28-03-2018 IPR023365 Sortase domain CWM22_RS12300 1170958f889a5ae66b562d820d316067 303 Gene3D G3DSA:2.40.260.10 50 261 9.9E-51 T 28-03-2018 IPR023365 Sortase domain CWM22_RS12300 1170958f889a5ae66b562d820d316067 303 TIGRFAM TIGR01076 sortase_fam: sortase 116 249 4.2E-56 T 28-03-2018 IPR005754 Sortase family CWM22_RS12300 1170958f889a5ae66b562d820d316067 303 Pfam PF04203 Sortase family 118 242 2.4E-22 T 28-03-2018 IPR005754 Sortase family CWM22_RS02390 a9e3539298c9a6c89dc4c1a4910a14e9 327 Pfam PF00581 Rhodanese-like domain 121 215 7.0E-12 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS02390 a9e3539298c9a6c89dc4c1a4910a14e9 327 SMART SM00450 120 221 8.3E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS02390 a9e3539298c9a6c89dc4c1a4910a14e9 327 Hamap MF_00469 UPF0176 protein YceA [yceA]. 3 272 39.853 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 CWM22_RS02390 a9e3539298c9a6c89dc4c1a4910a14e9 327 Gene3D G3DSA:3.40.250.10 114 317 1.0E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS02390 a9e3539298c9a6c89dc4c1a4910a14e9 327 Pfam PF12368 Rhodanase C-terminal 227 293 4.7E-13 T 28-03-2018 IPR022111 Rhodanase, C-terminal CWM22_RS02390 a9e3539298c9a6c89dc4c1a4910a14e9 327 SUPERFAMILY SSF52821 111 253 1.96E-34 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS10200 a641b1cf8e18f7c10ad3b25fec6b7cd1 445 Gene3D G3DSA:3.30.465.10 345 434 8.0E-17 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWM22_RS10200 a641b1cf8e18f7c10ad3b25fec6b7cd1 445 SMART SM01091 352 436 2.7E-15 T 28-03-2018 IPR005170 Transporter-associated domain CWM22_RS10200 a641b1cf8e18f7c10ad3b25fec6b7cd1 445 Pfam PF01595 Domain of unknown function DUF21 14 200 3.7E-46 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CWM22_RS10200 a641b1cf8e18f7c10ad3b25fec6b7cd1 445 Gene3D G3DSA:3.10.580.10 195 344 4.0E-33 T 28-03-2018 CWM22_RS10200 a641b1cf8e18f7c10ad3b25fec6b7cd1 445 SUPERFAMILY SSF56176 353 433 1.77E-18 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWM22_RS10200 a641b1cf8e18f7c10ad3b25fec6b7cd1 445 Pfam PF03471 Transporter associated domain 353 433 2.3E-16 T 28-03-2018 IPR005170 Transporter-associated domain CWM22_RS10200 a641b1cf8e18f7c10ad3b25fec6b7cd1 445 SUPERFAMILY SSF54631 203 340 1.89E-29 T 28-03-2018 CWM22_RS10200 a641b1cf8e18f7c10ad3b25fec6b7cd1 445 Pfam PF00571 CBS domain 284 337 3.5E-5 T 28-03-2018 IPR000644 CBS domain CWM22_RS10200 a641b1cf8e18f7c10ad3b25fec6b7cd1 445 Pfam PF00571 CBS domain 218 271 4.5E-4 T 28-03-2018 IPR000644 CBS domain CWM22_RS03200 b3a1d8204dad1f54cd85a310588523bd 243 Pfam PF00005 ABC transporter 18 164 3.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS03200 b3a1d8204dad1f54cd85a310588523bd 243 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS03200 b3a1d8204dad1f54cd85a310588523bd 243 SMART SM00382 27 214 3.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS03200 b3a1d8204dad1f54cd85a310588523bd 243 Gene3D G3DSA:3.40.50.300 1 241 1.9E-75 T 28-03-2018 CWM22_RS03200 b3a1d8204dad1f54cd85a310588523bd 243 SUPERFAMILY SSF52540 1 239 5.9E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07140 707b38edfad9605a0a04d07c59e14f4d 578 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS07140 707b38edfad9605a0a04d07c59e14f4d 578 SUPERFAMILY SSF52540 321 569 3.88E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07140 707b38edfad9605a0a04d07c59e14f4d 578 Pfam PF00005 ABC transporter 350 497 5.9E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS07140 707b38edfad9605a0a04d07c59e14f4d 578 Gene3D G3DSA:1.20.1560.10 1 318 1.8E-65 T 28-03-2018 CWM22_RS07140 707b38edfad9605a0a04d07c59e14f4d 578 SUPERFAMILY SSF90123 4 313 2.35E-67 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS07140 707b38edfad9605a0a04d07c59e14f4d 578 SMART SM00382 359 551 3.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS07140 707b38edfad9605a0a04d07c59e14f4d 578 Pfam PF00664 ABC transporter transmembrane region 20 280 9.0E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS07140 707b38edfad9605a0a04d07c59e14f4d 578 Gene3D G3DSA:3.40.50.300 319 575 1.9E-71 T 28-03-2018 CWM22_RS07705 4f0db5bfef3eae62eb17f7425b992031 333 SUPERFAMILY SSF51569 10 326 8.06E-68 T 28-03-2018 CWM22_RS07705 4f0db5bfef3eae62eb17f7425b992031 333 TIGRFAM TIGR01232 lacD: tagatose 1,6-diphosphate aldolase 7 330 2.2E-133 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWM22_RS07705 4f0db5bfef3eae62eb17f7425b992031 333 Gene3D G3DSA:3.20.20.70 7 333 4.2E-78 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS07705 4f0db5bfef3eae62eb17f7425b992031 333 Hamap MF_00734 Tagatose 1,6-diphosphate aldolase [lacD]. 1 333 190.399 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWM22_RS07705 4f0db5bfef3eae62eb17f7425b992031 333 Pfam PF01791 DeoC/LacD family aldolase 24 286 1.1E-60 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWM22_RS07705 4f0db5bfef3eae62eb17f7425b992031 333 SMART SM01133 24 287 6.7E-30 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWM22_RS04445 2da7855b34c7f5a998b90092ff96e4ea 829 TIGRFAM TIGR03728 glyco_access_1: glycosyltransferase, SP_1767 family 10 271 4.1E-117 T 28-03-2018 IPR014869 Glycosyltransferase GT-D fold CWM22_RS04445 2da7855b34c7f5a998b90092ff96e4ea 829 Pfam PF01501 Glycosyl transferase family 8 288 526 7.9E-39 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CWM22_RS04445 2da7855b34c7f5a998b90092ff96e4ea 829 Gene3D G3DSA:3.90.550.10 551 827 2.2E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04445 2da7855b34c7f5a998b90092ff96e4ea 829 SUPERFAMILY SSF53448 286 528 2.39E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04445 2da7855b34c7f5a998b90092ff96e4ea 829 SUPERFAMILY SSF53448 554 716 6.38E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04445 2da7855b34c7f5a998b90092ff96e4ea 829 Gene3D G3DSA:3.90.550.10 286 549 2.6E-49 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04445 2da7855b34c7f5a998b90092ff96e4ea 829 Pfam PF00535 Glycosyl transferase family 2 557 681 2.9E-11 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS04445 2da7855b34c7f5a998b90092ff96e4ea 829 Pfam PF08759 Glycosyltransferase GT-D fold 27 249 6.5E-93 T 28-03-2018 IPR014869 Glycosyltransferase GT-D fold CWM22_RS06955 ba857f866d5a84c51d6671c7f17ed9bd 319 Gene3D G3DSA:3.30.420.40 1 124 7.9E-29 T 28-03-2018 CWM22_RS06955 ba857f866d5a84c51d6671c7f17ed9bd 319 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 317 8.9E-102 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CWM22_RS06955 ba857f866d5a84c51d6671c7f17ed9bd 319 Pfam PF00480 ROK family 6 318 2.4E-72 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWM22_RS06955 ba857f866d5a84c51d6671c7f17ed9bd 319 Gene3D G3DSA:3.30.420.40 125 319 6.1E-58 T 28-03-2018 CWM22_RS06955 ba857f866d5a84c51d6671c7f17ed9bd 319 ProSitePatterns PS01125 ROK family signature. 139 166 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWM22_RS06955 ba857f866d5a84c51d6671c7f17ed9bd 319 SUPERFAMILY SSF53067 4 318 1.34E-70 T 28-03-2018 CWM22_RS04275 6000a9738ff6f8117bd1467a3fcd081a 375 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 3 368 4.4E-128 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWM22_RS04275 6000a9738ff6f8117bd1467a3fcd081a 375 Gene3D G3DSA:3.90.1510.10 42 270 7.0E-68 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CWM22_RS04275 6000a9738ff6f8117bd1467a3fcd081a 375 SUPERFAMILY SSF110738 1 368 3.4E-121 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWM22_RS04275 6000a9738ff6f8117bd1467a3fcd081a 375 Pfam PF02595 Glycerate kinase family 3 366 2.7E-119 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWM22_RS04275 6000a9738ff6f8117bd1467a3fcd081a 375 PIRSF PIRSF006078 1 370 2.3E-114 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 6 158 4.6E-53 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 Gene3D G3DSA:3.40.50.620 1 161 2.2E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 SUPERFAMILY SSF52374 4 158 4.35E-37 T 28-03-2018 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 88 104 6.0E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 51 75 6.0E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 6.0E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 115 137 6.0E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 6.0E-35 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 161 31.191 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 Pfam PF01467 Cytidylyltransferase-like 7 136 4.0E-15 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWM22_RS10275 e72c07fb765a0275804d5a85851850f0 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 59 2.8E-15 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 SUPERFAMILY SSF53244 305 450 5.49E-29 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 Gene3D G3DSA:3.40.1390.10 1 88 8.3E-23 T 28-03-2018 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 Pfam PF02875 Mur ligase family, glutamate ligase domain 306 386 1.1E-9 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 SUPERFAMILY SSF63418 3 95 7.06E-21 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 Pfam PF08245 Mur ligase middle domain 104 283 3.6E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 449 1.5E-107 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 Gene3D G3DSA:3.40.1190.10 89 302 1.7E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 452 31.484 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 SUPERFAMILY SSF53623 100 301 6.28E-45 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS08840 7da69eb1ea53dc30f9cdc5ae05abc9f2 453 Gene3D G3DSA:3.90.190.20 303 453 8.1E-34 T 28-03-2018 CWM22_RS00445 54990b1e47f44f3e8ea9bff5245abb07 189 Gene3D G3DSA:1.10.340.30 1 183 1.3E-76 T 28-03-2018 CWM22_RS00445 54990b1e47f44f3e8ea9bff5245abb07 189 Pfam PF03352 Methyladenine glycosylase 6 180 5.1E-74 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CWM22_RS00445 54990b1e47f44f3e8ea9bff5245abb07 189 SUPERFAMILY SSF48150 1 183 2.42E-75 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CWM22_RS10750 6fb342fa7c50b06de149c9567a133341 285 Gene3D G3DSA:3.40.190.10 160 285 2.8E-37 T 28-03-2018 CWM22_RS10750 6fb342fa7c50b06de149c9567a133341 285 Pfam PF03180 NLPA lipoprotein 38 285 2.5E-88 T 28-03-2018 IPR004872 Lipoprotein NlpA family CWM22_RS10750 6fb342fa7c50b06de149c9567a133341 285 SUPERFAMILY SSF53850 37 285 1.42E-68 T 28-03-2018 CWM22_RS10750 6fb342fa7c50b06de149c9567a133341 285 PIRSF PIRSF002854 1 285 2.4E-80 T 28-03-2018 IPR004872 Lipoprotein NlpA family CWM22_RS10750 6fb342fa7c50b06de149c9567a133341 285 Gene3D G3DSA:3.40.190.10 37 159 5.7E-33 T 28-03-2018 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 SUPERFAMILY SSF53748 3 398 5.3E-142 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PIRSF PIRSF000724 1 399 8.5E-131 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 Gene3D G3DSA:3.40.50.1260 4 186 4.5E-65 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 Gene3D G3DSA:3.40.50.1260 187 386 6.0E-75 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.2E-91 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PRINTS PR00477 Phosphoglycerate kinase family signature 198 217 1.2E-91 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PRINTS PR00477 Phosphoglycerate kinase family signature 175 197 1.2E-91 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PRINTS PR00477 Phosphoglycerate kinase family signature 374 391 1.2E-91 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PRINTS PR00477 Phosphoglycerate kinase family signature 317 342 1.2E-91 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PRINTS PR00477 Phosphoglycerate kinase family signature 111 126 1.2E-91 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.2E-91 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PRINTS PR00477 Phosphoglycerate kinase family signature 144 166 1.2E-91 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 PRINTS PR00477 Phosphoglycerate kinase family signature 351 362 1.2E-91 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 Pfam PF00162 Phosphoglycerate kinase 6 388 7.9E-146 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01045 7b2f9f9a52b297a86890f4080f7d784b 399 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 398 39.616 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS03335 8d1710241d966d2e68d432a08c96fc85 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 117 4.2E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWM22_RS03335 8d1710241d966d2e68d432a08c96fc85 125 Gene3D G3DSA:3.10.180.10 1 123 4.6E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS03335 8d1710241d966d2e68d432a08c96fc85 125 SUPERFAMILY SSF54593 1 123 1.17E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS05020 e74fb6f3fd8066ddb3864ddea6f9d62a 92 Hamap MF_01041 UPF0223 protein . 3 90 24.223 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CWM22_RS05020 e74fb6f3fd8066ddb3864ddea6f9d62a 92 SUPERFAMILY SSF158504 6 89 1.03E-31 T 28-03-2018 IPR023324 BH2638-like domain CWM22_RS05020 e74fb6f3fd8066ddb3864ddea6f9d62a 92 PIRSF PIRSF037260 1 92 5.6E-37 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CWM22_RS05020 e74fb6f3fd8066ddb3864ddea6f9d62a 92 Gene3D G3DSA:1.10.220.80 14 90 5.4E-29 T 28-03-2018 IPR023324 BH2638-like domain CWM22_RS05020 e74fb6f3fd8066ddb3864ddea6f9d62a 92 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 4 81 2.0E-27 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CWM22_RS05020 e74fb6f3fd8066ddb3864ddea6f9d62a 92 Pfam PF05256 Uncharacterised protein family (UPF0223) 4 87 1.0E-33 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 SUPERFAMILY SSF53738 160 255 2.39E-23 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 Gene3D G3DSA:3.40.120.10 152 262 9.3E-23 T 28-03-2018 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 253 3.2E-16 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 136 2.0E-41 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 4.2E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 4.2E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 4.2E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 SUPERFAMILY SSF53738 257 365 7.46E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 Gene3D G3DSA:3.40.120.10 1 151 5.9E-44 T 28-03-2018 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 43.817 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 Gene3D G3DSA:3.30.310.50 374 448 3.2E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 443 3.6E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 SUPERFAMILY SSF55957 357 447 8.11E-25 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 Gene3D G3DSA:3.40.120.10 263 373 6.7E-32 T 28-03-2018 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 366 2.3E-32 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 4.5E-192 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04570 36d51c36cd03ae8a34c82ffe92e631a3 449 SUPERFAMILY SSF53738 3 179 3.3E-41 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS01440 a559ec35712fa445bd5652d541fb8d37 125 SUPERFAMILY SSF46955 2 111 1.9E-29 T 28-03-2018 IPR009061 Putative DNA-binding domain CWM22_RS01440 a559ec35712fa445bd5652d541fb8d37 125 Gene3D G3DSA:1.10.1660.10 53 123 6.3E-13 T 28-03-2018 CWM22_RS01440 a559ec35712fa445bd5652d541fb8d37 125 Gene3D G3DSA:1.10.10.60 1 14 0.38 T 28-03-2018 CWM22_RS01440 a559ec35712fa445bd5652d541fb8d37 125 Gene3D G3DSA:1.10.1660.10 15 52 6.6E-19 T 28-03-2018 CWM22_RS01440 a559ec35712fa445bd5652d541fb8d37 125 Pfam PF13411 MerR HTH family regulatory protein 1 59 2.6E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS01440 a559ec35712fa445bd5652d541fb8d37 125 SMART SM00422 1 67 1.2E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS02315 19306634493ad5f31cdd411e19bbc877 390 SUPERFAMILY SSF55729 1 160 6.36E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS02315 19306634493ad5f31cdd411e19bbc877 390 SUPERFAMILY SSF55729 165 240 1.73E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS02315 19306634493ad5f31cdd411e19bbc877 390 SUPERFAMILY SSF55729 287 383 1.73E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS02315 19306634493ad5f31cdd411e19bbc877 390 Gene3D G3DSA:3.40.630.30 164 363 7.2E-32 T 28-03-2018 CWM22_RS02315 19306634493ad5f31cdd411e19bbc877 390 Gene3D G3DSA:3.40.630.30 1 163 1.1E-24 T 28-03-2018 CWM22_RS02315 19306634493ad5f31cdd411e19bbc877 390 Pfam PF02388 FemAB family 6 387 9.6E-106 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CWM22_RS06510 171cf39e2eceeb28335bd4e7ad3f9956 358 Pfam PF13155 Toprim-like 199 322 1.9E-10 T 28-03-2018 CWM22_RS06510 171cf39e2eceeb28335bd4e7ad3f9956 358 SMART SM00400 34 79 0.0084 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWM22_RS06510 171cf39e2eceeb28335bd4e7ad3f9956 358 Gene3D G3DSA:3.90.580.10 1 81 1.9E-13 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWM22_RS06510 171cf39e2eceeb28335bd4e7ad3f9956 358 Gene3D G3DSA:3.40.1360.10 179 341 1.8E-21 T 28-03-2018 CWM22_RS06510 171cf39e2eceeb28335bd4e7ad3f9956 358 SUPERFAMILY SSF57783 4 79 3.91E-12 T 28-03-2018 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00691 Adhesin B signature 56 74 7.8E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00691 Adhesin B signature 75 94 7.8E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00691 Adhesin B signature 233 250 7.8E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00691 Adhesin B signature 31 52 7.8E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00691 Adhesin B signature 184 201 7.8E-17 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 SUPERFAMILY SSF53807 29 307 9.81E-67 T 28-03-2018 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 Gene3D G3DSA:3.40.50.1980 179 307 9.2E-38 T 28-03-2018 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 Pfam PF01297 Zinc-uptake complex component A periplasmic 34 304 2.0E-63 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 Gene3D G3DSA:3.40.50.1980 20 178 8.7E-37 T 28-03-2018 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00690 Adhesin family signature 272 291 1.0E-27 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00690 Adhesin family signature 31 49 1.0E-27 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00690 Adhesin family signature 75 92 1.0E-27 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00690 Adhesin family signature 184 205 1.0E-27 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS12645 c6df2025415c8b8cc21e551d7ab504d5 307 PRINTS PR00690 Adhesin family signature 62 75 1.0E-27 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 SUPERFAMILY SSF50447 843 939 1.41E-26 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Gene3D G3DSA:3.30.56.50 4 46 2.0E-12 T 28-03-2018 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Gene3D G3DSA:3.30.56.50 365 406 2.0E-10 T 28-03-2018 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 940 16.922 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Gene3D G3DSA:3.40.50.10050 740 821 3.6E-27 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 ProSitePatterns PS01176 Initiation factor 2 signature. 893 915 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Pfam PF11987 Translation-initiation factor 2 727 832 1.4E-36 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Gene3D G3DSA:2.40.30.10 843 940 1.4E-24 T 28-03-2018 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Pfam PF00009 Elongation factor Tu GTP binding domain 447 603 8.7E-35 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 SUPERFAMILY SSF52156 719 849 4.45E-39 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 PRINTS PR00449 Transforming protein P21 ras signature 445 466 1.3E-5 T 28-03-2018 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 PRINTS PR00449 Transforming protein P21 ras signature 484 506 1.3E-5 T 28-03-2018 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 PRINTS PR00449 Transforming protein P21 ras signature 542 555 1.3E-5 T 28-03-2018 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 PRINTS PR00449 Transforming protein P21 ras signature 583 605 1.3E-5 T 28-03-2018 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 SUPERFAMILY SSF52540 431 615 1.47E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 356 940 1.8E-246 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 SUPERFAMILY SSF50447 617 697 3.53E-22 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 444 601 1.4E-35 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Gene3D G3DSA:3.40.50.300 437 607 7.2E-42 T 28-03-2018 CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 51 5.0E-15 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 363 413 1.1E-12 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CWM22_RS11260 d042f36a1c3b9686741ad4c07b6996c9 940 Gene3D G3DSA:2.40.30.10 608 706 1.0E-12 T 28-03-2018 CWM22_RS05365 791b8ee9cb0a580a5cad4caedd77a694 324 SUPERFAMILY SSF53659 1 320 4.52E-93 T 28-03-2018 CWM22_RS05365 791b8ee9cb0a580a5cad4caedd77a694 324 Pfam PF01515 Phosphate acetyl/butaryl transferase 3 317 6.8E-115 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWM22_RS05365 791b8ee9cb0a580a5cad4caedd77a694 324 Gene3D G3DSA:3.40.50.10750 140 293 3.6E-63 T 28-03-2018 CWM22_RS05365 791b8ee9cb0a580a5cad4caedd77a694 324 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 18 317 2.1E-114 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWM22_RS05365 791b8ee9cb0a580a5cad4caedd77a694 324 PIRSF PIRSF000428 1 324 1.1E-103 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 SMART SM00437 269 528 1.2E-56 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 SMART SM00493 2 126 4.1E-14 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 306 320 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 Gene3D G3DSA:1.10.460.10 158 362 3.4E-33 T 28-03-2018 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 Gene3D G3DSA:1.10.460.10 465 582 1.1E-15 T 28-03-2018 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 SMART SM00436 128 228 1.1E-29 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 SUPERFAMILY SSF56712 3 574 3.14E-129 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 198 216 3.0E-21 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 489 503 3.0E-21 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 311 320 3.0E-21 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 3.0E-21 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 391 407 3.0E-21 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 Gene3D G3DSA:3.40.50.140 2 156 4.8E-26 T 28-03-2018 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 Pfam PF01131 DNA topoisomerase 156 564 1.4E-100 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 Pfam PF01751 Toprim domain 4 136 1.1E-10 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS09085 2f994014a4c95f32a9af2151c8c3c0bf 582 Gene3D G3DSA:2.70.20.10 363 464 2.1E-20 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CWM22_RS10545 c34c598733c443a27bd0d88572fa8750 229 SUPERFAMILY SSF52172 3 181 1.57E-18 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS10545 c34c598733c443a27bd0d88572fa8750 229 Pfam PF00072 Response regulator receiver domain 5 114 7.7E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS10545 c34c598733c443a27bd0d88572fa8750 229 SUPERFAMILY SSF46894 136 227 8.79E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWM22_RS10545 c34c598733c443a27bd0d88572fa8750 229 Gene3D G3DSA:3.40.50.2300 2 133 3.4E-16 T 28-03-2018 CWM22_RS10545 c34c598733c443a27bd0d88572fa8750 229 SMART SM00448 3 114 0.0029 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS10545 c34c598733c443a27bd0d88572fa8750 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 227 3.6E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS10545 c34c598733c443a27bd0d88572fa8750 229 SMART SM00862 153 227 1.0E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS10545 c34c598733c443a27bd0d88572fa8750 229 Gene3D G3DSA:1.10.10.10 134 229 3.0E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12325 fa95b2ab0ee2e335e27f9111b9fdc3ba 164 Pfam PF00484 Carbonic anhydrase 32 100 9.4E-14 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWM22_RS12325 fa95b2ab0ee2e335e27f9111b9fdc3ba 164 SUPERFAMILY SSF53056 4 162 9.29E-41 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWM22_RS12325 fa95b2ab0ee2e335e27f9111b9fdc3ba 164 SMART SM00947 24 164 2.8E-33 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWM22_RS12325 fa95b2ab0ee2e335e27f9111b9fdc3ba 164 Gene3D G3DSA:3.40.1050.10 1 164 1.5E-38 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWM22_RS09765 47ec5c20aabc3794bb74645e28f68cda 138 Hamap MF_00984 Single-stranded DNA-binding protein. 2 108 35.511 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWM22_RS09765 47ec5c20aabc3794bb74645e28f68cda 138 Pfam PF00436 Single-strand binding protein family 2 104 1.1E-36 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWM22_RS09765 47ec5c20aabc3794bb74645e28f68cda 138 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 115 1.3E-40 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWM22_RS09765 47ec5c20aabc3794bb74645e28f68cda 138 Gene3D G3DSA:2.40.50.140 1 112 4.2E-41 T 28-03-2018 CWM22_RS09765 47ec5c20aabc3794bb74645e28f68cda 138 PIRSF PIRSF002070 1 129 3.6E-38 T 28-03-2018 CWM22_RS09765 47ec5c20aabc3794bb74645e28f68cda 138 SUPERFAMILY SSF50249 1 138 9.26E-51 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS05110 8f089fb78dfd83f2325d199137b3e09b 129 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWM22_RS05110 8f089fb78dfd83f2325d199137b3e09b 129 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 101 4.5E-18 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWM22_RS05110 8f089fb78dfd83f2325d199137b3e09b 129 SUPERFAMILY SSF53927 5 126 1.4E-44 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWM22_RS05110 8f089fb78dfd83f2325d199137b3e09b 129 Gene3D G3DSA:3.40.140.10 1 128 2.7E-46 T 28-03-2018 CWM22_RS05110 8f089fb78dfd83f2325d199137b3e09b 129 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 6 126 1.6E-45 T 28-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CWM22_RS06530 22e1b7626aa65ac62f9c13fbbb3097c9 158 Gene3D G3DSA:1.10.260.40 1 66 3.5E-18 T 28-03-2018 CWM22_RS06530 22e1b7626aa65ac62f9c13fbbb3097c9 158 SMART SM00530 5 60 3.9E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS06530 22e1b7626aa65ac62f9c13fbbb3097c9 158 SUPERFAMILY SSF47413 2 64 1.25E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS06530 22e1b7626aa65ac62f9c13fbbb3097c9 158 Pfam PF01381 Helix-turn-helix 6 58 6.7E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS06530 22e1b7626aa65ac62f9c13fbbb3097c9 158 Gene3D G3DSA:1.10.8.130 72 156 8.1E-38 T 28-03-2018 IPR035569 Antitoxin epsilon/PezA domain CWM22_RS13135 0b27bc8813ba88b6c1813476919d66bc 419 Pfam PF13416 Bacterial extracellular solute-binding protein 57 355 1.4E-48 T 28-03-2018 CWM22_RS13135 0b27bc8813ba88b6c1813476919d66bc 419 SUPERFAMILY SSF53850 40 409 2.0E-79 T 28-03-2018 CWM22_RS13135 0b27bc8813ba88b6c1813476919d66bc 419 Gene3D G3DSA:3.40.190.10 40 160 4.2E-14 T 28-03-2018 CWM22_RS13135 0b27bc8813ba88b6c1813476919d66bc 419 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 140 157 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 CWM22_RS13135 0b27bc8813ba88b6c1813476919d66bc 419 PRINTS PR00181 Maltose binding protein signature 372 391 4.0E-7 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CWM22_RS13135 0b27bc8813ba88b6c1813476919d66bc 419 PRINTS PR00181 Maltose binding protein signature 158 177 4.0E-7 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CWM22_RS13135 0b27bc8813ba88b6c1813476919d66bc 419 PRINTS PR00181 Maltose binding protein signature 137 156 4.0E-7 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CWM22_RS13135 0b27bc8813ba88b6c1813476919d66bc 419 PRINTS PR00181 Maltose binding protein signature 314 335 4.0E-7 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CWM22_RS13135 0b27bc8813ba88b6c1813476919d66bc 419 Gene3D G3DSA:3.40.190.10 161 347 4.2E-38 T 28-03-2018 CWM22_RS01220 201337e567fe014bf9194bb7f649fb52 99 SUPERFAMILY SSF82607 4 95 8.11E-25 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWM22_RS01220 201337e567fe014bf9194bb7f649fb52 99 PIRSF PIRSF004555 1 99 2.3E-24 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWM22_RS01220 201337e567fe014bf9194bb7f649fb52 99 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 90 1.7E-20 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWM22_RS01220 201337e567fe014bf9194bb7f649fb52 99 Pfam PF02575 YbaB/EbfC DNA-binding family 8 97 1.0E-24 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWM22_RS01220 201337e567fe014bf9194bb7f649fb52 99 Gene3D G3DSA:3.30.1310.10 1 99 3.5E-27 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWM22_RS01220 201337e567fe014bf9194bb7f649fb52 99 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 18.864 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWM22_RS05435 df37d737c4554c0094a126140818f91c 507 Pfam PF00005 ABC transporter 335 457 4.6E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05435 df37d737c4554c0094a126140818f91c 507 Pfam PF00005 ABC transporter 21 157 8.9E-11 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05435 df37d737c4554c0094a126140818f91c 507 Gene3D G3DSA:3.40.50.300 1 291 3.0E-30 T 28-03-2018 CWM22_RS05435 df37d737c4554c0094a126140818f91c 507 SUPERFAMILY SSF52540 305 503 8.38E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05435 df37d737c4554c0094a126140818f91c 507 SMART SM00382 343 502 7.1E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05435 df37d737c4554c0094a126140818f91c 507 SMART SM00382 29 202 7.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05435 df37d737c4554c0094a126140818f91c 507 ProSitePatterns PS00211 ABC transporters family signature. 430 444 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05435 df37d737c4554c0094a126140818f91c 507 Gene3D G3DSA:3.40.50.300 292 506 4.5E-34 T 28-03-2018 CWM22_RS05435 df37d737c4554c0094a126140818f91c 507 SUPERFAMILY SSF52540 17 200 2.35E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 SUPERFAMILY SSF46934 3 56 6.38E-18 T 28-03-2018 IPR009060 UBA-like GO:0005515 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 Gene3D G3DSA:3.30.479.20 230 339 2.0E-23 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 Gene3D G3DSA:3.30.479.20 159 229 2.5E-10 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 340 1.9E-94 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 Hamap MF_00050 Elongation factor Ts [tsf]. 1 341 67.455 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 Gene3D G3DSA:1.10.8.10 1 56 1.1E-23 T 28-03-2018 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 Pfam PF00889 Elongation factor TS 71 323 2.7E-66 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 Gene3D G3DSA:3.30.479.20 58 158 2.1E-20 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 SUPERFAMILY SSF54713 249 323 1.24E-36 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 SUPERFAMILY SSF54713 177 206 1.24E-36 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS11935 decb2857990dfff38ecb7fca20418923 346 SUPERFAMILY SSF54713 57 92 1.24E-36 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:2.40.30.10 248 340 9.1E-12 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF52540 2 235 3.08E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF54211 416 532 1.06E-21 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Pfam PF00679 Elongation factor G C-terminus 534 615 2.2E-16 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.30.70.240 543 618 6.7E-13 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF54980 535 618 7.19E-16 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Pfam PF14492 Elongation Factor G, domain II 342 414 2.8E-12 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.30.230.10 433 542 2.0E-18 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.40.50.300 1 67 2.6E-9 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.30.70.870 341 432 2.0E-14 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF54980 342 418 3.6E-14 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 162 8.1E-41 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Pfam PF03764 Elongation factor G, domain IV 416 531 1.7E-22 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF50447 223 324 2.05E-14 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.40.50.300 68 247 4.0E-29 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 Pfam PF00009 Elongation factor Tu GTP binding domain 2 237 6.0E-60 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 SMART SM00889 417 532 1.6E-14 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 213 235 5.6E-77 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 267 293 5.6E-77 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 455 469 5.6E-77 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 504 521 5.6E-77 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 5.6E-77 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 470 492 5.6E-77 T 28-03-2018 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 123 132 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 5 18 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 51 59 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 87 98 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS06415 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 71 81 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:2.40.30.10 248 340 9.1E-12 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF52540 2 235 3.08E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF54211 416 532 1.06E-21 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Pfam PF00679 Elongation factor G C-terminus 534 615 2.2E-16 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.30.70.240 543 618 6.7E-13 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF54980 535 618 7.19E-16 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Pfam PF14492 Elongation Factor G, domain II 342 414 2.8E-12 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.30.230.10 433 542 2.0E-18 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.40.50.300 1 67 2.6E-9 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.30.70.870 341 432 2.0E-14 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF54980 342 418 3.6E-14 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 162 8.1E-41 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Pfam PF03764 Elongation factor G, domain IV 416 531 1.7E-22 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 SUPERFAMILY SSF50447 223 324 2.05E-14 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Gene3D G3DSA:3.40.50.300 68 247 4.0E-29 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 Pfam PF00009 Elongation factor Tu GTP binding domain 2 237 6.0E-60 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 SMART SM00889 417 532 1.6E-14 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 213 235 5.6E-77 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 267 293 5.6E-77 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 455 469 5.6E-77 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 504 521 5.6E-77 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 5.6E-77 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 470 492 5.6E-77 T 28-03-2018 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 123 132 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 5 18 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 51 59 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 87 98 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS05695 1241dc52e14b9a42e149b1b44d974ef5 639 PRINTS PR00315 GTP-binding elongation factor signature 71 81 7.8E-18 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS03240 90fffce083dfaef72737a209ec4cafd5 670 Pfam PF02687 FtsX-like permease family 87 175 2.6E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWM22_RS03240 90fffce083dfaef72737a209ec4cafd5 670 PIRSF PIRSF018968 4 670 8.1E-71 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWM22_RS11120 c5ff6b1ee300940918e0b7203b37dd9e 104 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 9 101 3.1E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS11120 c5ff6b1ee300940918e0b7203b37dd9e 104 Gene3D G3DSA:1.20.58.80 4 102 5.1E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS11120 c5ff6b1ee300940918e0b7203b37dd9e 104 SUPERFAMILY SSF46973 1 102 2.75E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS11120 c5ff6b1ee300940918e0b7203b37dd9e 104 PIRSF PIRSF000699 1 104 7.7E-38 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS00410 17a57cb951fd31aa881acbd516e26f0f 406 Pfam PF08245 Mur ligase middle domain 40 254 7.8E-10 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS00410 17a57cb951fd31aa881acbd516e26f0f 406 TIGRFAM TIGR01499 folC: bifunctional protein FolC 19 403 3.8E-118 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CWM22_RS00410 17a57cb951fd31aa881acbd516e26f0f 406 SUPERFAMILY SSF53244 284 405 2.52E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS00410 17a57cb951fd31aa881acbd516e26f0f 406 SUPERFAMILY SSF53623 5 282 5.5E-82 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS00410 17a57cb951fd31aa881acbd516e26f0f 406 PIRSF PIRSF001563 1 406 2.2E-121 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CWM22_RS00410 17a57cb951fd31aa881acbd516e26f0f 406 Gene3D G3DSA:3.40.1190.10 2 283 1.7E-75 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS00410 17a57cb951fd31aa881acbd516e26f0f 406 Gene3D G3DSA:3.90.190.20 284 406 3.5E-15 T 28-03-2018 CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 4.4E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 403 4.4E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 4.4E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 439 451 4.4E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 4.4E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 Gene3D G3DSA:3.20.20.80 1 477 1.8E-156 T 28-03-2018 CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 Pfam PF00232 Glycosyl hydrolase family 1 3 474 6.4E-133 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 SUPERFAMILY SSF51445 2 470 2.35E-166 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS11145 aec44d97b1f001d2f990183324d361f3 477 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWM22_RS04270 8c750aaec8668e02aec5caea5183ab41 216 Gene3D G3DSA:1.10.150.240 29 73 2.0E-21 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWM22_RS04270 8c750aaec8668e02aec5caea5183ab41 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 183 4.4E-32 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS04270 8c750aaec8668e02aec5caea5183ab41 216 SUPERFAMILY SSF56784 1 213 6.2E-59 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS04270 8c750aaec8668e02aec5caea5183ab41 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 176 6.6E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS04270 8c750aaec8668e02aec5caea5183ab41 216 Gene3D G3DSA:3.40.50.1000 74 215 2.5E-32 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS04270 8c750aaec8668e02aec5caea5183ab41 216 Gene3D G3DSA:3.40.50.1000 1 28 0.074 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10290 9b4d363433553b4993120d1dc76a7bd9 128 Pfam PF00581 Rhodanese-like domain 35 122 1.3E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS10290 9b4d363433553b4993120d1dc76a7bd9 128 SMART SM00450 30 126 2.7E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS10290 9b4d363433553b4993120d1dc76a7bd9 128 SUPERFAMILY SSF52821 10 122 3.8E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS10290 9b4d363433553b4993120d1dc76a7bd9 128 Gene3D G3DSA:3.40.250.10 21 128 9.4E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 408 482 2.0E-8 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 Gene3D G3DSA:1.10.260.40 1 73 2.7E-13 T 28-03-2018 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 282 371 1.3E-26 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 SUPERFAMILY SSF47413 11 73 7.51E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 84 486 6.3E-92 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 SMART SM00530 14 69 2.3E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 SMART SM00984 407 495 1.3E-12 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 Gene3D G3DSA:3.40.50.720 82 283 2.0E-46 T 28-03-2018 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 SUPERFAMILY SSF48179 281 377 8.84E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 Gene3D G3DSA:3.40.50.720 305 490 4.5E-45 T 28-03-2018 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 SUPERFAMILY SSF52413 401 496 4.32E-25 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 Pfam PF01381 Helix-turn-helix 18 65 2.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 PIRSF PIRSF500134 84 451 1.6E-115 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 PIRSF PIRSF500134 445 496 0.18 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 Gene3D G3DSA:1.20.5.100 284 304 2.6E-14 T 28-03-2018 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 SUPERFAMILY SSF51735 84 284 1.16E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 85 247 5.3E-31 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWM22_RS03620 b65f49bd4fca06e8d2f544a35b26fa6e 496 PIRSF PIRSF000124 84 496 3.2E-127 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CWM22_RS06450 d5d883f152ce575882224b95f8535e23 341 Pfam PF13481 AAA domain 13 175 1.4E-23 T 28-03-2018 CWM22_RS06450 d5d883f152ce575882224b95f8535e23 341 SUPERFAMILY SSF52540 28 223 1.9E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06450 d5d883f152ce575882224b95f8535e23 341 Gene3D G3DSA:3.40.50.300 25 243 1.4E-16 T 28-03-2018 CWM22_RS05730 d5d883f152ce575882224b95f8535e23 341 Pfam PF13481 AAA domain 13 175 1.4E-23 T 28-03-2018 CWM22_RS05730 d5d883f152ce575882224b95f8535e23 341 SUPERFAMILY SSF52540 28 223 1.9E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05730 d5d883f152ce575882224b95f8535e23 341 Gene3D G3DSA:3.40.50.300 25 243 1.4E-16 T 28-03-2018 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 Pfam PF00005 ABC transporter 624 860 2.5E-11 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 SMART SM00382 633 908 1.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 Gene3D G3DSA:3.40.50.300 433 616 3.5E-23 T 28-03-2018 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 SUPERFAMILY SSF52540 6 205 3.32E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 SUPERFAMILY SSF52540 432 571 3.32E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 Gene3D G3DSA:3.40.50.300 1 36 0.0038 T 28-03-2018 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 940 22.651 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 SUPERFAMILY SSF52540 616 914 7.88E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 Gene3D G3DSA:3.30.190.20 128 246 3.6E-42 T 28-03-2018 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 Gene3D G3DSA:3.40.50.300 617 941 6.7E-60 T 28-03-2018 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 925 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 Gene3D G3DSA:3.40.50.300 37 114 2.6E-4 T 28-03-2018 CWM22_RS11055 61221441dc81d5766f0524ee81845e32 941 Gene3D G3DSA:1.10.8.280 283 403 1.7E-38 T 28-03-2018 CWM22_RS04985 63a2021e1aa7ee8cbcfa36568170f75b 910 Gene3D G3DSA:3.40.50.300 581 749 8.4E-28 T 28-03-2018 CWM22_RS04985 63a2021e1aa7ee8cbcfa36568170f75b 910 Pfam PF13086 AAA domain 187 538 5.8E-28 T 28-03-2018 CWM22_RS04985 63a2021e1aa7ee8cbcfa36568170f75b 910 Gene3D G3DSA:3.40.50.300 185 557 2.5E-32 T 28-03-2018 CWM22_RS04985 63a2021e1aa7ee8cbcfa36568170f75b 910 Pfam PF10881 Protein of unknown function (DUF2726) 783 904 7.6E-11 T 28-03-2018 IPR024402 Domain of unknown function DUF2726 CWM22_RS04985 63a2021e1aa7ee8cbcfa36568170f75b 910 Gene3D G3DSA:3.40.960.10 810 905 9.5E-7 T 28-03-2018 CWM22_RS04985 63a2021e1aa7ee8cbcfa36568170f75b 910 Pfam PF13087 AAA domain 562 723 2.1E-22 T 28-03-2018 CWM22_RS04985 63a2021e1aa7ee8cbcfa36568170f75b 910 SUPERFAMILY SSF52540 185 327 8.54E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04985 63a2021e1aa7ee8cbcfa36568170f75b 910 SUPERFAMILY SSF52540 464 728 8.54E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01215 2c3edb1f0b8cad8f7c029b11475817ec 588 SUPERFAMILY SSF51695 335 560 6.02E-48 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS01215 2c3edb1f0b8cad8f7c029b11475817ec 588 Gene3D G3DSA:3.20.20.190 330 568 9.9E-40 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS01215 2c3edb1f0b8cad8f7c029b11475817ec 588 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 4 317 5.8E-72 T 28-03-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain CWM22_RS01215 2c3edb1f0b8cad8f7c029b11475817ec 588 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 340 556 4.5E-23 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 88 99 - T 28-03-2018 IPR018215 ClpP, Ser active site CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 Gene3D G3DSA:3.90.226.10 1 194 3.9E-43 T 28-03-2018 CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 Pfam PF00574 Clp protease 10 192 1.1E-78 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 110 123 - T 28-03-2018 IPR033135 ClpP, histidine active site CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 88 105 6.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 109 128 6.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 17 32 6.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 57 77 6.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 6.5E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 193 39.794 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWM22_RS08670 ea6a950eab52f847093b11de842b7d0e 196 SUPERFAMILY SSF52096 8 194 3.23E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWM22_RS12155 2bc4cde36f39f7754f97da8042940d09 290 SUPERFAMILY SSF53335 15 287 2.5E-75 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS12155 2bc4cde36f39f7754f97da8042940d09 290 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 18 286 55.389 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CWM22_RS12155 2bc4cde36f39f7754f97da8042940d09 290 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 18 284 4.2E-83 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CWM22_RS12155 2bc4cde36f39f7754f97da8042940d09 290 Pfam PF00398 Ribosomal RNA adenine dimethylase 18 251 5.7E-66 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CWM22_RS12155 2bc4cde36f39f7754f97da8042940d09 290 SMART SM00650 34 210 1.4E-86 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CWM22_RS12155 2bc4cde36f39f7754f97da8042940d09 290 Gene3D G3DSA:3.40.50.150 3 224 1.1E-59 T 28-03-2018 CWM22_RS12155 2bc4cde36f39f7754f97da8042940d09 290 Gene3D G3DSA:1.10.8.100 225 287 1.0E-19 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CWM22_RS12155 2bc4cde36f39f7754f97da8042940d09 290 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 50 77 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 SUPERFAMILY SSF52943 4 291 1.16E-83 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 Gene3D G3DSA:1.10.287.80 183 272 1.1E-26 T 28-03-2018 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 Gene3D G3DSA:1.10.287.80 3 62 2.3E-15 T 28-03-2018 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 Gene3D G3DSA:3.40.1380.10 67 182 4.2E-34 T 28-03-2018 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 4 291 7.9E-95 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 PRINTS PR00126 ATP synthase gamma subunit signature 77 96 1.5E-32 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 PRINTS PR00126 ATP synthase gamma subunit signature 238 257 1.5E-32 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 PRINTS PR00126 ATP synthase gamma subunit signature 170 187 1.5E-32 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 PRINTS PR00126 ATP synthase gamma subunit signature 269 290 1.5E-32 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 291 31.676 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 Pfam PF00231 ATP synthase 4 291 5.7E-85 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08165 b4ef03d12ccf16ea6252a5331183d9d6 292 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 277 290 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 SUPERFAMILY SSF50129 1 93 8.01E-24 T 28-03-2018 IPR011032 GroES-like CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 PRINTS PR00297 10kDa chaperonin signature 23 44 2.0E-19 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 PRINTS PR00297 10kDa chaperonin signature 2 17 2.0E-19 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 PRINTS PR00297 10kDa chaperonin signature 79 92 2.0E-19 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 PRINTS PR00297 10kDa chaperonin signature 58 70 2.0E-19 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 SMART SM00883 1 92 4.6E-36 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 Gene3D G3DSA:2.30.33.40 1 93 1.0E-23 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 25 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 Pfam PF00166 Chaperonin 10 Kd subunit 2 92 7.8E-21 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWM22_RS01000 f2796a255983c9c45210c8b09c7fe44a 93 Hamap MF_00580 10 kDa chaperonin [groS]. 1 93 18.64 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWM22_RS12605 33b33785cb5765c648c7b1ffd6b3c595 277 Gene3D G3DSA:3.40.1440.10 178 277 1.3E-13 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS12605 33b33785cb5765c648c7b1ffd6b3c595 277 SUPERFAMILY SSF82771 179 275 1.01E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS02010 dfb28ab002691a4464e1268c449c5aac 172 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 1.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS02010 dfb28ab002691a4464e1268c449c5aac 172 SUPERFAMILY SSF46689 14 72 1.03E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS02010 dfb28ab002691a4464e1268c449c5aac 172 Gene3D G3DSA:1.10.10.60 51 156 1.4E-6 T 28-03-2018 CWM22_RS02010 dfb28ab002691a4464e1268c449c5aac 172 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS02010 dfb28ab002691a4464e1268c449c5aac 172 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS02010 dfb28ab002691a4464e1268c449c5aac 172 Gene3D G3DSA:1.10.10.60 3 50 1.2E-11 T 28-03-2018 CWM22_RS01490 cf1d8017b1c197445fae2a5d4314b474 282 Gene3D G3DSA:2.30.30.60 131 183 1.6E-11 T 28-03-2018 CWM22_RS01490 cf1d8017b1c197445fae2a5d4314b474 282 SUPERFAMILY SSF82689 184 275 1.83E-5 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CWM22_RS01490 cf1d8017b1c197445fae2a5d4314b474 282 Gene3D G3DSA:3.30.70.100 184 276 9.3E-6 T 28-03-2018 CWM22_RS01490 cf1d8017b1c197445fae2a5d4314b474 282 Pfam PF00924 Mechanosensitive ion channel 73 272 9.1E-41 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CWM22_RS01490 cf1d8017b1c197445fae2a5d4314b474 282 SUPERFAMILY SSF82861 23 114 1.09E-15 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CWM22_RS01490 cf1d8017b1c197445fae2a5d4314b474 282 SUPERFAMILY SSF50182 116 176 5.56E-12 T 28-03-2018 IPR010920 LSM domain CWM22_RS09375 32adb752fe49421d53fd118b5b2d0a34 286 Pfam PF09313 Domain of unknown function (DUF1971) 8 88 3.9E-28 T 28-03-2018 IPR015392 Domain of unknown function DUF1971 CWM22_RS09375 32adb752fe49421d53fd118b5b2d0a34 286 Pfam PF03848 Tellurite resistance protein TehB 90 281 4.5E-94 T 28-03-2018 IPR015985 Tellurite resistance methyltransferase TehB-like domain CWM22_RS09375 32adb752fe49421d53fd118b5b2d0a34 286 Gene3D G3DSA:2.60.120.10 2 96 4.8E-35 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWM22_RS09375 32adb752fe49421d53fd118b5b2d0a34 286 PIRSF PIRSF005215 1 286 1.4E-135 T 28-03-2018 IPR014431 Tellurite resistance methyltransferase, TehB type-2 CWM22_RS09375 32adb752fe49421d53fd118b5b2d0a34 286 SUPERFAMILY SSF53335 67 270 8.13E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS09375 32adb752fe49421d53fd118b5b2d0a34 286 SUPERFAMILY SSF51197 4 101 7.69E-35 T 28-03-2018 CWM22_RS09375 32adb752fe49421d53fd118b5b2d0a34 286 TIGRFAM TIGR00477 tehB: tellurite resistance protein TehB 49 284 3.7E-109 T 28-03-2018 IPR004537 Tellurite resistance methyltransferase, TehB GO:0005737|GO:0008757|GO:0046690 CWM22_RS09375 32adb752fe49421d53fd118b5b2d0a34 286 Gene3D G3DSA:3.40.50.150 97 285 4.8E-28 T 28-03-2018 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 Gene3D G3DSA:3.40.190.10 152 293 2.4E-35 T 28-03-2018 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 5.5E-51 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 173 192 5.5E-51 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 299 325 5.5E-51 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 5.5E-51 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 5.5E-51 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 5.5E-51 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 155 169 5.5E-51 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 5.5E-51 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 254 273 5.5E-51 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 Pfam PF13416 Bacterial extracellular solute-binding protein 50 318 1.7E-36 T 28-03-2018 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 PIRSF PIRSF019574 1 355 9.8E-123 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 Gene3D G3DSA:3.40.190.10 22 151 7.2E-27 T 28-03-2018 CWM22_RS07095 1c57c8d45f47df2ce941f632c831c704 356 SUPERFAMILY SSF53850 35 352 9.57E-91 T 28-03-2018 CWM22_RS00360 0a9983802f2768a0be2266fd90994501 290 SUPERFAMILY SSF52540 2 212 3.22E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00360 0a9983802f2768a0be2266fd90994501 290 Gene3D G3DSA:3.40.50.300 1 258 4.1E-56 T 28-03-2018 CWM22_RS00360 0a9983802f2768a0be2266fd90994501 290 Pfam PF00005 ABC transporter 19 158 2.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS00360 0a9983802f2768a0be2266fd90994501 290 SMART SM00382 28 208 4.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 231 2.2E-53 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 SUPERFAMILY SSF81338 3 235 5.63E-67 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 ProSitePatterns PS00221 MIP family signature. 63 71 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 PRINTS PR00783 Major intrinsic protein family signature 167 189 1.2E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 PRINTS PR00783 Major intrinsic protein family signature 214 234 1.2E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 PRINTS PR00783 Major intrinsic protein family signature 45 69 1.2E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 PRINTS PR00783 Major intrinsic protein family signature 137 155 1.2E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 PRINTS PR00783 Major intrinsic protein family signature 82 101 1.2E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 PRINTS PR00783 Major intrinsic protein family signature 3 22 1.2E-40 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 Pfam PF00230 Major intrinsic protein 3 231 1.8E-38 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS07445 623501ebee3afbfa3c491cdb4f1f390d 235 Gene3D G3DSA:1.20.1080.10 1 235 2.8E-78 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWM22_RS08770 030b64745965536c31eb7dd23c639954 135 Pfam PF13673 Acetyltransferase (GNAT) domain 31 126 3.9E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS08770 030b64745965536c31eb7dd23c639954 135 Gene3D G3DSA:3.40.630.30 1 135 1.0E-23 T 28-03-2018 CWM22_RS08770 030b64745965536c31eb7dd23c639954 135 SUPERFAMILY SSF55729 1 127 3.76E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS05725 865913459ea91eb047608f3251737fc5 157 Gene3D G3DSA:1.10.10.10 80 156 1.7E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05725 865913459ea91eb047608f3251737fc5 157 SUPERFAMILY SSF88659 83 152 6.35E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS06445 865913459ea91eb047608f3251737fc5 157 Gene3D G3DSA:1.10.10.10 80 156 1.7E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06445 865913459ea91eb047608f3251737fc5 157 SUPERFAMILY SSF88659 83 152 6.35E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS09380 9d8f3c431bd3d25ba7d7c549bd470209 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CWM22_RS09380 9d8f3c431bd3d25ba7d7c549bd470209 347 SMART SM00829 10 344 0.0054 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWM22_RS09380 9d8f3c431bd3d25ba7d7c549bd470209 347 Gene3D G3DSA:3.90.180.10 1 165 4.7E-39 T 28-03-2018 CWM22_RS09380 9d8f3c431bd3d25ba7d7c549bd470209 347 SUPERFAMILY SSF50129 1 181 4.09E-40 T 28-03-2018 IPR011032 GroES-like CWM22_RS09380 9d8f3c431bd3d25ba7d7c549bd470209 347 SUPERFAMILY SSF51735 150 288 1.07E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS09380 9d8f3c431bd3d25ba7d7c549bd470209 347 Pfam PF00107 Zinc-binding dehydrogenase 181 275 1.6E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWM22_RS09380 9d8f3c431bd3d25ba7d7c549bd470209 347 Gene3D G3DSA:3.40.50.720 166 290 1.9E-19 T 28-03-2018 CWM22_RS09380 9d8f3c431bd3d25ba7d7c549bd470209 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 108 7.0E-20 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 TIGRFAM TIGR03726 strep_RK_lipo: putative cross-wall-targeting lipoprotein signal 11 41 3.2E-8 T 28-03-2018 IPR021197 Cross-wall-targeting lipoprotein motif CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 806 978 2.2E-59 T 28-03-2018 IPR026345 Adhesin isopeptide-forming adherence domain CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 Gene3D G3DSA:2.60.40.740 649 798 0.025 T 28-03-2018 CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 Pfam PF00746 LPXTG cell wall anchor motif 1152 1187 4.1E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 Pfam PF08363 Glucan-binding protein C 283 548 3.7E-37 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1155 1186 3.0E-6 T 28-03-2018 CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 SUPERFAMILY SSF74914 257 570 2.09E-53 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 Gene3D G3DSA:2.60.40.740 991 1145 3.0E-11 T 28-03-2018 CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 Pfam PF16364 Cell surface antigen C-terminus 979 1135 5.3E-46 T 28-03-2018 IPR032300 Cell surface antigen, C-terminal CWM22_RS12925 5ca7c706e09d13609c4b8dc2717d2af2 1189 Gene3D G3DSA:3.40.50.300 77 645 2.4E-5 T 28-03-2018 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 SMART SM00437 254 515 4.2E-107 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Pfam PF01751 Toprim domain 17 125 2.0E-30 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Pfam PF01131 DNA topoisomerase 140 553 7.0E-132 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 SMART SM00493 15 115 2.8E-29 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 SUPERFAMILY SSF57783 577 618 1.12E-12 T 28-03-2018 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 663 687 0.74 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 583 618 1.7E-14 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 622 660 1.0E-12 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 SUPERFAMILY SSF56712 15 594 5.36E-193 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 SMART SM00436 116 204 5.6E-51 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Gene3D G3DSA:3.30.65.10 618 657 4.5E-9 T 28-03-2018 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Gene3D G3DSA:3.30.65.10 569 617 6.5E-17 T 28-03-2018 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Gene3D G3DSA:3.30.65.10 658 690 0.0014 T 28-03-2018 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 17 617 3.0E-243 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Gene3D G3DSA:1.10.460.10 147 335 1.9E-46 T 28-03-2018 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Gene3D G3DSA:1.10.460.10 457 568 4.7E-25 T 28-03-2018 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Hamap MF_00952 DNA topoisomerase 1 [topA]. 15 638 55.558 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 291 314 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 381 397 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 478 492 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 174 192 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 89 102 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 305 314 1.4E-36 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Gene3D G3DSA:2.70.20.10 337 456 2.6E-36 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CWM22_RS06055 99d50160dbcb09f77c22cdffdfddecaf 697 Gene3D G3DSA:3.40.50.140 14 141 1.4E-39 T 28-03-2018 CWM22_RS02975 048075ab75e82f57e831288d9b0b14ac 277 SUPERFAMILY SSF52266 48 270 3.38E-40 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWM22_RS02975 048075ab75e82f57e831288d9b0b14ac 277 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 52 259 3.2E-29 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWM22_RS02975 048075ab75e82f57e831288d9b0b14ac 277 Gene3D G3DSA:3.40.50.1110 44 274 1.6E-39 T 28-03-2018 CWM22_RS07495 aa218a4251144b7171ce3e647fd83a07 318 Gene3D G3DSA:3.40.50.1970 8 124 1.2E-6 T 28-03-2018 CWM22_RS07495 aa218a4251144b7171ce3e647fd83a07 318 SUPERFAMILY SSF56796 3 225 1.22E-15 T 28-03-2018 CWM22_RS12095 465d10f880e031f5ac8fd46ed24374ba 291 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 1 280 37.889 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CWM22_RS12095 465d10f880e031f5ac8fd46ed24374ba 291 Gene3D G3DSA:1.10.40.50 218 285 2.3E-23 T 28-03-2018 CWM22_RS12095 465d10f880e031f5ac8fd46ed24374ba 291 Gene3D G3DSA:3.40.50.300 61 215 7.8E-21 T 28-03-2018 CWM22_RS12095 465d10f880e031f5ac8fd46ed24374ba 291 Pfam PF03193 RsgA GTPase 58 215 3.4E-57 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CWM22_RS12095 465d10f880e031f5ac8fd46ed24374ba 291 SUPERFAMILY SSF52540 64 280 3.18E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12095 465d10f880e031f5ac8fd46ed24374ba 291 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 273 1.4E-72 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CWM22_RS12095 465d10f880e031f5ac8fd46ed24374ba 291 Gene3D G3DSA:2.40.50.140 1 60 6.3E-23 T 28-03-2018 CWM22_RS12095 465d10f880e031f5ac8fd46ed24374ba 291 SUPERFAMILY SSF50249 2 62 1.11E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS12095 465d10f880e031f5ac8fd46ed24374ba 291 Pfam PF16745 RsgA N-terminal domain 2 55 2.2E-25 T 28-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CWM22_RS10220 485da3226a6cdcff8319c7455de73f9d 181 SUPERFAMILY SSF53335 7 141 9.93E-20 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS10220 485da3226a6cdcff8319c7455de73f9d 181 Pfam PF06962 Putative rRNA methylase 43 177 3.1E-48 T 28-03-2018 IPR010719 Putative rRNA methylase CWM22_RS10220 485da3226a6cdcff8319c7455de73f9d 181 Gene3D G3DSA:3.40.50.150 2 181 3.9E-18 T 28-03-2018 CWM22_RS08155 644034aebd2c9a543e1f3458076b10c5 138 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 135 22.143 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08155 644034aebd2c9a543e1f3458076b10c5 138 Gene3D G3DSA:1.20.5.440 92 137 2.6E-14 T 28-03-2018 CWM22_RS08155 644034aebd2c9a543e1f3458076b10c5 138 Gene3D G3DSA:2.60.15.10 1 91 1.2E-23 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08155 644034aebd2c9a543e1f3458076b10c5 138 SUPERFAMILY SSF51344 3 87 6.67E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08155 644034aebd2c9a543e1f3458076b10c5 138 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 135 3.7E-13 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08155 644034aebd2c9a543e1f3458076b10c5 138 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 20 91 1.0E-16 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08155 644034aebd2c9a543e1f3458076b10c5 138 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 135 1.4E-27 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08155 644034aebd2c9a543e1f3458076b10c5 138 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 85 2.2E-24 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS01805 2d21e39bfa4f2ee0538ba5c2d8e37090 1074 Gene3D G3DSA:2.60.40.10 973 1065 9.1E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS01805 2d21e39bfa4f2ee0538ba5c2d8e37090 1074 Gene3D G3DSA:2.60.40.10 579 677 5.4E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS01805 2d21e39bfa4f2ee0538ba5c2d8e37090 1074 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 16 37 1.4E-5 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide CWM22_RS00480 ae3557f79ddc185c3258c9a22afe9032 192 Pfam PF06042 Nucleotidyltransferase 32 189 3.0E-49 T 28-03-2018 IPR009267 Putative nucleotidyltransferase CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 8 257 1.8E-107 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 SUPERFAMILY SSF52096 8 256 2.34E-82 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 8 96 8.5E-41 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 Gene3D G3DSA:3.90.226.10 2 254 6.1E-65 T 28-03-2018 CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 101 114 3.0E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 61 79 3.0E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 36 47 3.0E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 117 130 3.0E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 145 154 3.0E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 82 98 3.0E-43 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10900 8326bca521f6871a30b4e89a47585011 257 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 257 35.828 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 4.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 4.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 Gene3D G3DSA:1.10.260.40 1 54 1.2E-19 T 28-03-2018 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 Gene3D G3DSA:3.40.50.2300 178 318 1.4E-25 T 28-03-2018 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 Gene3D G3DSA:3.40.50.2300 55 177 8.2E-27 T 28-03-2018 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 3.4E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 61 313 6.9E-21 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 SMART SM00354 2 72 2.7E-34 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 SUPERFAMILY SSF47413 2 60 2.25E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS13155 660c9d696e236ae633194df48abd28d1 327 SUPERFAMILY SSF53822 60 314 4.08E-45 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 Gene3D G3DSA:1.10.730.10 541 667 7.7E-4 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 Gene3D G3DSA:1.10.3210.10 331 540 1.8E-6 T 28-03-2018 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 675 25.979 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 242 257 2.1E-32 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 2.1E-32 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 2.1E-32 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 314 330 2.1E-32 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 2.1E-32 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 675 8.6E-210 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 SUPERFAMILY SSF109604 336 489 4.54E-17 T 28-03-2018 CWM22_RS10715 a2a8c56a49bea997e799fa51d8d96e82 678 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 548 4.1E-199 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS01375 700495636ff3cd84c42c04111ec95f60 370 Pfam PF01476 LysM domain 53 94 1.6E-9 T 28-03-2018 IPR018392 LysM domain CWM22_RS01375 700495636ff3cd84c42c04111ec95f60 370 SMART SM00257 52 96 9.1E-10 T 28-03-2018 IPR018392 LysM domain CWM22_RS01375 700495636ff3cd84c42c04111ec95f60 370 SUPERFAMILY SSF54106 51 94 7.32E-8 T 28-03-2018 IPR018392 LysM domain CWM22_RS01375 700495636ff3cd84c42c04111ec95f60 370 Gene3D G3DSA:3.10.350.10 46 101 4.3E-12 T 28-03-2018 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 Gene3D G3DSA:3.30.310.50 397 497 6.7E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 141 1.3E-24 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 Gene3D G3DSA:3.40.120.10 282 396 1.2E-19 T 28-03-2018 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 Gene3D G3DSA:3.40.120.10 166 281 6.7E-27 T 28-03-2018 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 Gene3D G3DSA:3.40.120.10 4 152 3.4E-27 T 28-03-2018 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 279 393 7.3E-13 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 SUPERFAMILY SSF53738 185 276 1.65E-23 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 SUPERFAMILY SSF53738 6 144 4.71E-25 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 169 274 3.6E-23 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 SUPERFAMILY SSF53738 279 393 8.24E-17 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 112 126 2.1E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 225 238 2.1E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 190 209 2.1E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS06705 fc2b3840b2870a99e64970e10183ba96 502 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 254 269 2.1E-19 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 SMART SM00958 231 343 7.9E-32 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 SUPERFAMILY SSF52540 353 400 3.67E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 SUPERFAMILY SSF52540 5 231 3.67E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 SUPERFAMILY SSF81886 581 792 1.26E-38 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 ProSitePatterns PS01312 SecA family signature. 485 500 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 SUPERFAMILY SSF81767 230 353 2.35E-33 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 Gene3D G3DSA:1.10.3060.10 608 781 1.2E-25 T 28-03-2018 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 Pfam PF07516 SecA Wing and Scaffold domain 581 777 3.9E-26 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 PRINTS PR00906 SecA protein signature 98 112 7.8E-52 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 PRINTS PR00906 SecA protein signature 361 378 7.8E-52 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 PRINTS PR00906 SecA protein signature 173 193 7.8E-52 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 PRINTS PR00906 SecA protein signature 60 84 7.8E-52 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 PRINTS PR00906 SecA protein signature 398 411 7.8E-52 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 PRINTS PR00906 SecA protein signature 324 346 7.8E-52 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 Gene3D G3DSA:3.40.50.300 7 245 2.9E-47 T 28-03-2018 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 SUPERFAMILY SSF52540 402 562 5.32E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 782 16.215 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 SMART SM00957 4 387 1.9E-189 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 Gene3D G3DSA:3.90.1440.10 246 353 2.7E-29 T 28-03-2018 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 TIGRFAM TIGR03714 secA2: accessory Sec system translocase SecA2 11 769 0.0 T 28-03-2018 IPR022490 Protein translocase subunit SecA2 GO:0015031|GO:0015450 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 Pfam PF01043 SecA preprotein cross-linking domain 235 343 2.1E-23 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 Pfam PF07517 SecA DEAD-like domain 9 386 1.5E-103 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWM22_RS04475 dc8fe4db454732cca1a529c42cf3e697 794 Gene3D G3DSA:3.40.50.300 402 607 2.6E-34 T 28-03-2018 CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 SUPERFAMILY SSF55021 298 360 5.73E-10 T 28-03-2018 CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 1.3E-85 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 Pfam PF00696 Amino acid kinase family 2 276 8.8E-46 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 Gene3D G3DSA:3.30.70.260 375 450 1.1E-19 T 28-03-2018 CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 Gene3D G3DSA:3.40.1160.10 1 281 3.0E-55 T 28-03-2018 CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 Gene3D G3DSA:3.30.70.260 282 374 4.6E-19 T 28-03-2018 CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 PIRSF PIRSF000726 1 451 1.9E-82 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 SUPERFAMILY SSF55021 373 450 1.41E-20 T 28-03-2018 CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 SUPERFAMILY SSF53633 1 289 5.63E-68 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWM22_RS10970 7528c1c4c05008ec6b783b9efad21482 451 Pfam PF13840 ACT domain 380 444 9.6E-12 T 28-03-2018 IPR027795 GATS-like ACT domain CWM22_RS12685 e3fc6c5827b649332fed20edfc606f2b 233 Pfam PF02517 CAAX protease self-immunity 131 217 2.1E-17 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS06710 c25b59fd57e4c6f83fbbe7bf26d4d97d 356 Hamap MF_01816 Tyrosine recombinase XerS [xerS]. 1 356 58.759 T 28-03-2018 IPR023670 Tyrosine recombinase XerS GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CWM22_RS06710 c25b59fd57e4c6f83fbbe7bf26d4d97d 356 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 33 122 1.8E-7 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWM22_RS06710 c25b59fd57e4c6f83fbbe7bf26d4d97d 356 Gene3D G3DSA:1.10.443.10 156 356 6.8E-32 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS06710 c25b59fd57e4c6f83fbbe7bf26d4d97d 356 SUPERFAMILY SSF56349 20 354 1.09E-34 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS06710 c25b59fd57e4c6f83fbbe7bf26d4d97d 356 Pfam PF00589 Phage integrase family 190 344 7.3E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS06710 c25b59fd57e4c6f83fbbe7bf26d4d97d 356 Gene3D G3DSA:1.10.150.130 12 154 3.1E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWM22_RS06875 ec9ba68e7c2d7174d08b411cb4c97a9a 200 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 3 190 4.6E-48 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CWM22_RS06875 ec9ba68e7c2d7174d08b411cb4c97a9a 200 Pfam PF01300 Telomere recombination 7 180 1.5E-44 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CWM22_RS06875 ec9ba68e7c2d7174d08b411cb4c97a9a 200 Gene3D G3DSA:3.90.870.10 1 196 4.2E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWM22_RS06875 ec9ba68e7c2d7174d08b411cb4c97a9a 200 SUPERFAMILY SSF55821 3 193 2.66E-54 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWM22_RS08025 86150f1e61a3887294ac39f24b2867fe 270 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 12 27 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWM22_RS08025 86150f1e61a3887294ac39f24b2867fe 270 SUPERFAMILY SSF51717 8 264 6.8E-94 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWM22_RS08025 86150f1e61a3887294ac39f24b2867fe 270 Gene3D G3DSA:3.20.20.20 9 139 6.8E-56 T 28-03-2018 CWM22_RS08025 86150f1e61a3887294ac39f24b2867fe 270 Gene3D G3DSA:3.20.20.20 140 267 1.2E-44 T 28-03-2018 CWM22_RS08025 86150f1e61a3887294ac39f24b2867fe 270 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 11 262 2.0E-100 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CWM22_RS08025 86150f1e61a3887294ac39f24b2867fe 270 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 46 59 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWM22_RS08025 86150f1e61a3887294ac39f24b2867fe 270 Pfam PF00809 Pterin binding enzyme 13 248 1.5E-84 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWM22_RS10500 b1d713972b6cd50f6463e2cdce9d502b 387 Gene3D G3DSA:1.10.10.60 2 47 2.7E-8 T 28-03-2018 CWM22_RS10500 b1d713972b6cd50f6463e2cdce9d502b 387 SUPERFAMILY SSF53098 206 356 2.09E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS10500 b1d713972b6cd50f6463e2cdce9d502b 387 Pfam PF13936 Helix-turn-helix domain 2 45 1.2E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CWM22_RS10500 b1d713972b6cd50f6463e2cdce9d502b 387 Gene3D G3DSA:3.30.420.10 202 363 5.9E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS03740 5cbf3d3f9b9afefc3e333dccaf41f3ee 446 Pfam PF01546 Peptidase family M20/M25/M40 82 441 3.6E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWM22_RS03740 5cbf3d3f9b9afefc3e333dccaf41f3ee 446 SUPERFAMILY SSF53187 8 185 1.07E-60 T 28-03-2018 CWM22_RS03740 5cbf3d3f9b9afefc3e333dccaf41f3ee 446 SUPERFAMILY SSF53187 361 444 1.07E-60 T 28-03-2018 CWM22_RS03740 5cbf3d3f9b9afefc3e333dccaf41f3ee 446 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 13 440 4.1E-138 T 28-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CWM22_RS03740 5cbf3d3f9b9afefc3e333dccaf41f3ee 446 Gene3D G3DSA:3.40.630.10 6 192 1.3E-26 T 28-03-2018 CWM22_RS03740 5cbf3d3f9b9afefc3e333dccaf41f3ee 446 Gene3D G3DSA:3.30.70.360 258 350 1.3E-18 T 28-03-2018 CWM22_RS03740 5cbf3d3f9b9afefc3e333dccaf41f3ee 446 SUPERFAMILY SSF55031 185 357 7.43E-35 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWM22_RS00900 0dc1094813d6e0a35b9f7ca652adfdc7 93 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 30 2.5E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWM22_RS00900 0dc1094813d6e0a35b9f7ca652adfdc7 93 Gene3D G3DSA:3.30.700.10 12 92 5.0E-9 T 28-03-2018 CWM22_RS00900 0dc1094813d6e0a35b9f7ca652adfdc7 93 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 30 2.6E-7 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWM22_RS00900 0dc1094813d6e0a35b9f7ca652adfdc7 93 PIRSF PIRSF029928 1 93 4.8E-36 T 28-03-2018 IPR016940 ComG operon protein C GO:0030420 CWM22_RS00900 0dc1094813d6e0a35b9f7ca652adfdc7 93 SUPERFAMILY SSF54523 12 88 1.1E-12 T 28-03-2018 CWM22_RS00900 0dc1094813d6e0a35b9f7ca652adfdc7 93 PRINTS PR00813 Bacterial general secretion pathway protein G signature 11 36 4.7E-8 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CWM22_RS00900 0dc1094813d6e0a35b9f7ca652adfdc7 93 PRINTS PR00813 Bacterial general secretion pathway protein G signature 47 65 4.7E-8 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CWM22_RS06250 cd527db83be0098a8d54c298716ffa34 297 SUPERFAMILY SSF53067 5 295 3.03E-45 T 28-03-2018 CWM22_RS06250 cd527db83be0098a8d54c298716ffa34 297 Gene3D G3DSA:3.30.420.40 146 279 3.6E-24 T 28-03-2018 CWM22_RS06250 cd527db83be0098a8d54c298716ffa34 297 Gene3D G3DSA:3.30.420.40 2 145 1.0E-35 T 28-03-2018 CWM22_RS06250 cd527db83be0098a8d54c298716ffa34 297 Pfam PF00480 ROK family 7 297 5.0E-48 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWM22_RS02255 a08f64d446e06bf76b9f7e5a506c5497 134 Gene3D G3DSA:1.10.287.900 1 16 5.7E-6 T 28-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 CWM22_RS02255 a08f64d446e06bf76b9f7e5a506c5497 134 SUPERFAMILY SSF55729 16 120 7.6E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS02255 a08f64d446e06bf76b9f7e5a506c5497 134 Pfam PF13302 Acetyltransferase (GNAT) domain 19 113 6.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS02255 a08f64d446e06bf76b9f7e5a506c5497 134 Gene3D G3DSA:3.40.630.30 17 130 1.5E-14 T 28-03-2018 CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 Gene3D G3DSA:3.40.1410.10 74 235 3.1E-36 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 Gene3D G3DSA:1.10.10.10 1 66 2.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 SMART SM00345 7 66 3.3E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 Pfam PF07702 UTRA domain 90 227 2.2E-35 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 62 2.9E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 SUPERFAMILY SSF64288 54 234 2.83E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 SUPERFAMILY SSF46785 1 76 4.49E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 SMART SM00866 89 228 1.9E-33 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 3.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS02340 080f44452ba3113b4078916635c4d4b5 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 3.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 Pfam PF16364 Cell surface antigen C-terminus 1410 1571 8.4E-61 T 28-03-2018 IPR032300 Cell surface antigen, C-terminal CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 Pfam PF08363 Glucan-binding protein C 370 434 1.7E-10 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 Pfam PF08363 Glucan-binding protein C 434 630 4.7E-64 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 Gene3D G3DSA:2.60.40.740 1070 1245 0.0035 T 28-03-2018 CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 Gene3D G3DSA:2.60.40.740 1248 1419 0.015 T 28-03-2018 CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 Gene3D G3DSA:2.60.40.740 1426 1586 1.3E-4 T 28-03-2018 CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 Gene3D G3DSA:2.60.40.740 894 1069 0.32 T 28-03-2018 CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 1237 1410 1.6E-62 T 28-03-2018 IPR026345 Adhesin isopeptide-forming adherence domain CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 883 1055 3.2E-56 T 28-03-2018 IPR026345 Adhesin isopeptide-forming adherence domain CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 1060 1233 2.4E-63 T 28-03-2018 IPR026345 Adhesin isopeptide-forming adherence domain CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 TIGRFAM TIGR03726 strep_RK_lipo: putative cross-wall-targeting lipoprotein signal 19 54 7.0E-17 T 28-03-2018 IPR021197 Cross-wall-targeting lipoprotein motif CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1600 1628 1.3E-4 T 28-03-2018 CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 SUPERFAMILY SSF74914 346 648 8.24E-78 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS06360 b0f3a6ddec52f80585ac4bd3e3213788 1631 Gene3D G3DSA:2.60.40.740 727 879 2.7E-4 T 28-03-2018 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 Pfam PF07499 RuvA, C-terminal domain 151 195 5.6E-8 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 2 195 5.9E-50 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 Gene3D G3DSA:1.10.150.20 54 80 0.1 T 28-03-2018 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 Pfam PF14520 Helix-hairpin-helix domain 71 127 7.0E-12 T 28-03-2018 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 Pfam PF01330 RuvA N terminal domain 1 61 2.7E-20 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 Gene3D G3DSA:1.10.150.20 81 135 2.3E-12 T 28-03-2018 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 Gene3D G3DSA:2.40.50.140 1 53 8.3E-22 T 28-03-2018 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 Gene3D G3DSA:1.10.8.10 136 195 1.9E-7 T 28-03-2018 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 195 29.058 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 SMART SM00278 107 126 78.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 SMART SM00278 72 91 2.1 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 SUPERFAMILY SSF50249 1 62 3.54E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 SUPERFAMILY SSF47781 65 131 5.84E-19 T 28-03-2018 IPR010994 RuvA domain 2-like CWM22_RS00440 b2a82a031dcea0153b0e79b4953b427c 196 SUPERFAMILY SSF46929 151 195 7.72E-9 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 Gene3D G3DSA:3.40.50.620 1 221 1.6E-65 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 Pfam PF01479 S4 domain 356 399 1.2E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 Pfam PF00579 tRNA synthetases class I (W and Y) 29 322 7.5E-82 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 SMART SM00363 352 414 3.2E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 4.1E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 4.1E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 4.1E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 4.1E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 SUPERFAMILY SSF52374 1 322 1.16E-107 T 28-03-2018 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 SUPERFAMILY SSF55174 321 417 8.51E-24 T 28-03-2018 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 Gene3D G3DSA:3.10.290.10 317 418 1.9E-22 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 44.477 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 416 1.4E-128 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWM22_RS00855 193f357b55c02154c594c30ff0fdab69 418 Gene3D G3DSA:1.10.240.10 222 316 3.5E-35 T 28-03-2018 CWM22_RS10375 70a48c91fdb55b615a9e4912f729673b 243 Gene3D G3DSA:3.10.290.10 1 58 1.2E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS10375 70a48c91fdb55b615a9e4912f729673b 243 Pfam PF00849 RNA pseudouridylate synthase 61 195 6.2E-22 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS10375 70a48c91fdb55b615a9e4912f729673b 243 SUPERFAMILY SSF55120 45 232 1.39E-46 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS10375 70a48c91fdb55b615a9e4912f729673b 243 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 225 5.0E-49 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWM22_RS10375 70a48c91fdb55b615a9e4912f729673b 243 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWM22_RS10375 70a48c91fdb55b615a9e4912f729673b 243 Gene3D G3DSA:3.30.2350.10 59 242 1.2E-41 T 28-03-2018 CWM22_RS10375 70a48c91fdb55b615a9e4912f729673b 243 Pfam PF01479 S4 domain 1 47 1.8E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS10375 70a48c91fdb55b615a9e4912f729673b 243 SUPERFAMILY SSF55174 1 56 8.83E-16 T 28-03-2018 CWM22_RS10375 70a48c91fdb55b615a9e4912f729673b 243 SMART SM00363 1 64 1.5E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 Pfam PF01470 Pyroglutamyl peptidase 1 201 3.3E-91 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 199 38.979 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 28-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 1.1E-47 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 1.1E-47 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 1.1E-47 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 1.1E-47 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 1.1E-47 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 Gene3D G3DSA:3.40.630.20 1 214 1.7E-66 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 PIRSF PIRSF015592 1 213 7.9E-83 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 212 1.9E-73 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CWM22_RS07160 3d48a16086624969e2ab2dfcbd3c77b6 215 SUPERFAMILY SSF53182 1 208 8.76E-72 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CWM22_RS12060 d8746f44906580d2ec9e654bbd4a038b 289 SMART SM00530 8 62 6.5E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12060 d8746f44906580d2ec9e654bbd4a038b 289 Pfam PF01381 Helix-turn-helix 9 62 1.9E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12060 d8746f44906580d2ec9e654bbd4a038b 289 SUPERFAMILY SSF47413 3 68 3.1E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS12060 d8746f44906580d2ec9e654bbd4a038b 289 Gene3D G3DSA:1.25.40.10 119 270 1.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS12060 d8746f44906580d2ec9e654bbd4a038b 289 Gene3D G3DSA:1.10.260.40 1 70 2.6E-18 T 28-03-2018 CWM22_RS10100 f63766be288997eff4c579ed54880bcb 179 Pfam PF02632 BioY family 29 166 2.4E-37 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CWM22_RS10100 f63766be288997eff4c579ed54880bcb 179 PIRSF PIRSF016661 1 178 3.5E-43 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CWM22_RS06060 a05d163daef497740fe90e23d138ff7d 164 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 4 161 26.46 T 28-03-2018 IPR022973 Ribosomal protein L10 CWM22_RS06060 a05d163daef497740fe90e23d138ff7d 164 SUPERFAMILY SSF160369 6 160 9.81E-51 T 28-03-2018 CWM22_RS06060 a05d163daef497740fe90e23d138ff7d 164 ProSitePatterns PS01109 Ribosomal protein L10 signature. 9 43 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS06060 a05d163daef497740fe90e23d138ff7d 164 Pfam PF00466 Ribosomal protein L10 7 101 5.2E-25 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 SMART SM00646 796 926 1.2E-40 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 SUPERFAMILY SSF53187 735 930 2.39E-51 T 28-03-2018 CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 737 925 3.3E-48 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Gene3D G3DSA:3.40.630.40 734 934 5.2E-58 T 28-03-2018 CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Gene3D G3DSA:2.60.40.10 417 514 0.31 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Gene3D G3DSA:2.60.40.10 317 414 0.31 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Gene3D G3DSA:2.60.40.10 517 614 0.31 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Gene3D G3DSA:2.60.40.10 216 314 0.44 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Gene3D G3DSA:2.60.40.10 617 733 0.086 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Pfam PF08481 GBS Bsp-like repeat 336 423 4.8E-28 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Pfam PF08481 GBS Bsp-like repeat 436 523 4.8E-28 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Pfam PF08481 GBS Bsp-like repeat 536 623 4.8E-28 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Pfam PF08481 GBS Bsp-like repeat 636 723 1.5E-28 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS07875 726d266ab405f6816737478d103d73a4 935 Pfam PF08481 GBS Bsp-like repeat 236 323 5.6E-27 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS10320 e5ae7fb5e5d4610ffb08ff48af78f8b9 172 PIRSF PIRSF005900 11 172 7.8E-44 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CWM22_RS10320 e5ae7fb5e5d4610ffb08ff48af78f8b9 172 SUPERFAMILY SSF47240 27 166 1.84E-41 T 28-03-2018 IPR009078 Ferritin-like superfamily CWM22_RS10320 e5ae7fb5e5d4610ffb08ff48af78f8b9 172 Gene3D G3DSA:1.20.1260.10 12 171 2.8E-42 T 28-03-2018 IPR012347 Ferritin-related CWM22_RS10320 e5ae7fb5e5d4610ffb08ff48af78f8b9 172 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 47 63 2.6E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CWM22_RS10320 e5ae7fb5e5d4610ffb08ff48af78f8b9 172 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 144 162 2.6E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CWM22_RS10320 e5ae7fb5e5d4610ffb08ff48af78f8b9 172 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 71 87 2.6E-12 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CWM22_RS10320 e5ae7fb5e5d4610ffb08ff48af78f8b9 172 Pfam PF00210 Ferritin-like domain 28 169 5.0E-28 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 Pfam PF00005 ABC transporter 499 647 1.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 ProSitePatterns PS00211 ABC transporters family signature. 619 633 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 SUPERFAMILY SSF90123 158 465 3.14E-57 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 SMART SM00382 507 692 1.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 Pfam PF03412 Peptidase C39 family 5 139 1.6E-28 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 Gene3D G3DSA:3.90.70.10 5 143 7.4E-31 T 28-03-2018 CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 Gene3D G3DSA:3.40.50.300 476 723 6.1E-67 T 28-03-2018 CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 Pfam PF00664 ABC transporter transmembrane region 168 436 1.6E-41 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 SUPERFAMILY SSF52540 475 717 3.41E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 TIGRFAM TIGR01193 bacteriocin_ABC: ABC-type bacteriocin transporter 10 713 4.4E-167 T 28-03-2018 IPR005897 Peptidase C39, ABC-type bacteriocin transporter GO:0008234|GO:0016020|GO:0022885|GO:0043213 CWM22_RS12055 6bd1f68ff931ba34786ff3a9ac03ee97 739 Gene3D G3DSA:1.20.1560.10 144 468 4.4E-47 T 28-03-2018 CWM22_RS07865 eeb698c783d8f18daee9585a119d439a 853 Pfam PF00884 Sulfatase 493 783 6.3E-27 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CWM22_RS07865 eeb698c783d8f18daee9585a119d439a 853 SUPERFAMILY SSF53649 493 759 1.07E-11 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWM22_RS07865 eeb698c783d8f18daee9585a119d439a 853 Gene3D G3DSA:3.40.720.10 491 837 5.1E-18 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWM22_RS03615 d637d85450faddc0e4d3dfc2e413809f 351 Gene3D G3DSA:3.90.25.10 189 351 6.6E-35 T 28-03-2018 CWM22_RS03615 d637d85450faddc0e4d3dfc2e413809f 351 Pfam PF16363 GDP-mannose 4,6 dehydratase 10 341 1.8E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS03615 d637d85450faddc0e4d3dfc2e413809f 351 PRINTS PR01713 Nucleotide sugar epimerase signature 263 278 8.2E-28 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS03615 d637d85450faddc0e4d3dfc2e413809f 351 PRINTS PR01713 Nucleotide sugar epimerase signature 37 53 8.2E-28 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS03615 d637d85450faddc0e4d3dfc2e413809f 351 PRINTS PR01713 Nucleotide sugar epimerase signature 312 329 8.2E-28 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS03615 d637d85450faddc0e4d3dfc2e413809f 351 PRINTS PR01713 Nucleotide sugar epimerase signature 229 244 8.2E-28 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS03615 d637d85450faddc0e4d3dfc2e413809f 351 Gene3D G3DSA:3.40.50.720 3 188 1.4E-31 T 28-03-2018 CWM22_RS03615 d637d85450faddc0e4d3dfc2e413809f 351 SUPERFAMILY SSF51735 7 350 1.17E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS08080 777ac1ed24a351eb1ed77194f9ab57b4 574 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 32 357 2.1E-52 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CWM22_RS08080 777ac1ed24a351eb1ed77194f9ab57b4 574 SUPERFAMILY SSF51445 14 399 5.16E-77 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS08080 777ac1ed24a351eb1ed77194f9ab57b4 574 Gene3D G3DSA:3.40.50.1700 392 560 5.6E-7 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CWM22_RS08080 777ac1ed24a351eb1ed77194f9ab57b4 574 Gene3D G3DSA:3.20.20.300 16 391 5.0E-68 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CWM22_RS11895 d6d6a2a70b12efbe7421650dcdb34251 743 Gene3D G3DSA:3.30.470.20 550 730 1.7E-19 T 28-03-2018 CWM22_RS11895 d6d6a2a70b12efbe7421650dcdb34251 743 TIGRFAM TIGR01435 glu_cys_lig_rel: glutamate--cysteine ligase/glutathione synthase 11 735 2.2E-242 T 28-03-2018 IPR006335 Glutathione biosynthesis bifunctional protein GshAB GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CWM22_RS11895 d6d6a2a70b12efbe7421650dcdb34251 743 Hamap MF_00782 Glutathione biosynthesis bifunctional protein GshAB [gshAB]. 1 743 410.394 T 28-03-2018 IPR006335 Glutathione biosynthesis bifunctional protein GshAB GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CWM22_RS11895 d6d6a2a70b12efbe7421650dcdb34251 743 Pfam PF04262 Glutamate-cysteine ligase 2 304 3.6E-74 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CWM22_RS11895 d6d6a2a70b12efbe7421650dcdb34251 743 Gene3D G3DSA:3.30.1490.20 446 549 1.9E-10 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWM22_RS11895 d6d6a2a70b12efbe7421650dcdb34251 743 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 476 574 1.9E-5 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWM22_RS11895 d6d6a2a70b12efbe7421650dcdb34251 743 SUPERFAMILY SSF56059 477 610 5.48E-28 T 28-03-2018 CWM22_RS11895 d6d6a2a70b12efbe7421650dcdb34251 743 SUPERFAMILY SSF56059 646 740 5.48E-28 T 28-03-2018 CWM22_RS11895 d6d6a2a70b12efbe7421650dcdb34251 743 SUPERFAMILY SSF55931 3 448 2.55E-139 T 28-03-2018 CWM22_RS00250 a24ce5dc508e95d3c84b67e45f609df5 340 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 5 340 45.707 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWM22_RS00250 a24ce5dc508e95d3c84b67e45f609df5 340 SUPERFAMILY SSF56042 170 338 2.84E-54 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWM22_RS00250 a24ce5dc508e95d3c84b67e45f609df5 340 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 162 1.4E-17 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWM22_RS00250 a24ce5dc508e95d3c84b67e45f609df5 340 Pfam PF02769 AIR synthase related protein, C-terminal domain 175 339 1.6E-35 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWM22_RS00250 a24ce5dc508e95d3c84b67e45f609df5 340 SUPERFAMILY SSF55326 6 169 2.39E-49 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWM22_RS00250 a24ce5dc508e95d3c84b67e45f609df5 340 Gene3D G3DSA:3.90.650.10 170 340 1.4E-56 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWM22_RS00250 a24ce5dc508e95d3c84b67e45f609df5 340 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 6 330 4.9E-134 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWM22_RS00250 a24ce5dc508e95d3c84b67e45f609df5 340 Gene3D G3DSA:3.30.1330.10 32 160 2.8E-55 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 78 1.0E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 Gene3D G3DSA:4.10.640.10 1 79 9.8E-34 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 Pfam PF01084 Ribosomal protein S18 22 73 6.0E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 SUPERFAMILY SSF46911 6 78 2.22E-30 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 2.3E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 2.3E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 2.3E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 2.3E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 77 5.0E-32 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11070 658b2bf4e3482ed60f70b4226ff5ae5f 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 78 22.794 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 Gene3D G3DSA:3.30.70.1510 5 81 2.1E-22 T 28-03-2018 CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 Gene3D G3DSA:3.30.2300.10 82 162 3.2E-19 T 28-03-2018 CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 405 167.299 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 Gene3D G3DSA:3.40.50.620 175 402 4.9E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 Pfam PF02926 THUMP domain 52 164 6.1E-19 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 370 5.3E-64 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 SUPERFAMILY SSF143437 3 173 4.36E-54 T 28-03-2018 CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 SMART SM00981 74 165 2.7E-22 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 SUPERFAMILY SSF52402 174 387 1.19E-51 T 28-03-2018 CWM22_RS07235 528730250d4838f81fe2d8ba379911df 405 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 372 6.3E-119 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CWM22_RS00640 e7f9c968ac448e3c16988d837b604551 426 SUPERFAMILY SSF55931 15 267 2.84E-36 T 28-03-2018 CWM22_RS00640 e7f9c968ac448e3c16988d837b604551 426 SUPERFAMILY SSF55931 305 418 2.84E-36 T 28-03-2018 CWM22_RS00640 e7f9c968ac448e3c16988d837b604551 426 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 66 209 7.3E-8 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CWM22_RS04140 2b72e134d578076546013910d1e39dff 1046 Gene3D G3DSA:1.10.287.1060 277 363 0.11 T 28-03-2018 CWM22_RS04140 2b72e134d578076546013910d1e39dff 1046 Gene3D G3DSA:1.20.120.20 585 704 5.9E-7 T 28-03-2018 CWM22_RS04140 2b72e134d578076546013910d1e39dff 1046 SUPERFAMILY SSF48371 607 824 2.3E-9 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWM22_RS04140 2b72e134d578076546013910d1e39dff 1046 SUPERFAMILY SSF48371 490 559 2.3E-9 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWM22_RS04140 2b72e134d578076546013910d1e39dff 1046 Gene3D G3DSA:1.20.120.20 411 580 0.059 T 28-03-2018 CWM22_RS04140 2b72e134d578076546013910d1e39dff 1046 Gene3D G3DSA:1.20.1420.10 13 260 0.19 T 28-03-2018 CWM22_RS04140 2b72e134d578076546013910d1e39dff 1046 Gene3D G3DSA:1.20.5.1230 705 826 5.1E-10 T 28-03-2018 CWM22_RS04140 2b72e134d578076546013910d1e39dff 1046 Gene3D G3DSA:1.10.287.700 874 940 1.9E-4 T 28-03-2018 CWM22_RS04140 2b72e134d578076546013910d1e39dff 1046 Gene3D G3DSA:1.10.287.700 827 873 5.1E-6 T 28-03-2018 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 505 549 3.5E-9 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 SUPERFAMILY SSF53738 26 236 1.84E-46 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 SUPERFAMILY SSF53738 209 312 4.32E-19 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 Gene3D G3DSA:3.40.120.10 337 455 1.9E-38 T 28-03-2018 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 179 1.2E-41 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 SUPERFAMILY SSF55957 444 481 1.28E-16 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 SUPERFAMILY SSF55957 512 571 1.28E-16 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 Gene3D G3DSA:3.40.120.10 212 336 2.5E-30 T 28-03-2018 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 Gene3D G3DSA:3.40.120.10 17 211 3.8E-53 T 28-03-2018 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 Gene3D G3DSA:3.30.310.50 467 572 2.0E-22 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 325 451 1.5E-23 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 209 311 1.5E-22 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 138 147 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 7.3E-5 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 137 151 7.3E-5 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07590 f0ab4380b8ba51fca6ae42dba4123149 572 SUPERFAMILY SSF53738 304 454 5.1E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 441 1.1E-11 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 Gene3D G3DSA:3.30.390.30 340 455 2.9E-20 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 317 3.5E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 8.4E-17 T 28-03-2018 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 8.4E-17 T 28-03-2018 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 261 8.4E-17 T 28-03-2018 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 8.4E-17 T 28-03-2018 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 SUPERFAMILY SSF51905 1 326 1.1E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 SUPERFAMILY SSF55424 333 454 4.81E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 Gene3D G3DSA:3.50.50.60 162 331 7.8E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 3.0E-25 T 28-03-2018 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.0E-25 T 28-03-2018 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.0E-25 T 28-03-2018 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 3.0E-25 T 28-03-2018 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 3.0E-25 T 28-03-2018 CWM22_RS07415 81cc46438d389b4ad02db8221429cce4 455 Gene3D G3DSA:3.50.50.60 2 147 5.7E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 350 7.1E-136 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 SUPERFAMILY SSF52540 32 223 1.06E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 Gene3D G3DSA:1.10.8.60 166 242 1.2E-19 T 28-03-2018 CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 SUPERFAMILY SSF48019 247 351 3.06E-14 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 Gene3D G3DSA:3.40.50.300 1 165 3.2E-41 T 28-03-2018 CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 123 141 1.7E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 40 58 1.7E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 Pfam PF13177 DNA polymerase III, delta subunit 19 177 1.8E-43 T 28-03-2018 CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 SMART SM00382 36 176 1.9E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 Gene3D G3DSA:1.20.272.10 243 356 3.4E-11 T 28-03-2018 CWM22_RS03070 5eba01486a57d86a260455d0fe166d46 555 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 352 4.5E-11 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 Pfam PF03449 Transcription elongation factor, N-terminal 7 76 4.5E-27 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 Gene3D G3DSA:1.10.287.180 5 77 5.4E-28 T 28-03-2018 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 7 157 1.6E-54 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 31.567 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 4.1E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 SUPERFAMILY SSF46557 4 79 4.58E-25 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 SUPERFAMILY SSF54534 83 157 1.83E-18 T 28-03-2018 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 PIRSF PIRSF006092 1 160 8.9E-48 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CWM22_RS10455 b97e17420ead8275f14d901fe8b099dd 160 Gene3D G3DSA:3.10.50.30 78 160 1.8E-23 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 181 3.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 ProSitePatterns PS00177 DNA topoisomerase II signature. 431 439 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 Pfam PF00204 DNA gyrase B 227 397 1.7E-55 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 SUPERFAMILY SSF54211 227 397 1.71E-52 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 SMART SM00387 36 182 4.7E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 9 643 50.678 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 9 646 0.0 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 SUPERFAMILY SSF56719 403 641 2.38E-86 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 Gene3D G3DSA:3.30.565.10 23 226 1.1E-74 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 Pfam PF01751 Toprim domain 428 538 1.1E-17 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 Gene3D G3DSA:3.30.230.10 227 399 7.8E-54 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 614 630 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 381 401 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 598 610 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 202 215 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 247 265 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 11 21 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 187 202 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 367 381 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 479 488 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR01159 DNA gyrase subunit B signature 317 333 2.4E-53 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 575 634 5.3E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 SUPERFAMILY SSF55874 10 224 4.85E-70 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 Gene3D G3DSA:3.40.50.670 410 641 6.2E-94 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR00418 DNA topoisomerase II family signature 495 511 3.7E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR00418 DNA topoisomerase II family signature 513 530 3.7E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR00418 DNA topoisomerase II family signature 75 88 3.7E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR00418 DNA topoisomerase II family signature 577 593 3.7E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR00418 DNA topoisomerase II family signature 117 131 3.7E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR00418 DNA topoisomerase II family signature 273 286 3.7E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR00418 DNA topoisomerase II family signature 40 55 3.7E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR00418 DNA topoisomerase II family signature 429 443 3.7E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 PRINTS PR00418 DNA topoisomerase II family signature 533 545 3.7E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07310 ab39da22d64fd7a96d7e6969277ee01a 649 SMART SM00433 40 638 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 Gene3D G3DSA:3.40.50.1440 9 215 1.5E-39 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 174 9.2E-40 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 SUPERFAMILY SSF55307 205 319 3.2E-42 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 Pfam PF12327 FtsZ family, C-terminal domain 223 316 6.8E-30 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 SMART SM00864 14 206 1.2E-109 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 PRINTS PR00423 Cell division protein FtsZ signature 190 212 4.3E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 PRINTS PR00423 Cell division protein FtsZ signature 213 234 4.3E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 PRINTS PR00423 Cell division protein FtsZ signature 127 148 4.3E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 PRINTS PR00423 Cell division protein FtsZ signature 99 119 4.3E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 SUPERFAMILY SSF52490 14 209 9.55E-67 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 Gene3D G3DSA:3.30.1330.20 216 324 1.3E-42 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 SMART SM00865 208 325 2.1E-49 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 384 37.83 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CWM22_RS02815 4dd391723a4a6819ea16e30bd6456d2b 409 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 327 4.4E-127 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 PIRSF PIRSF000447 2 411 4.1E-173 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 SMART SM00825 Beta-ketoacyl synthase 7 400 6.4E-13 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 365 2.2E-32 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 Gene3D G3DSA:3.40.47.10 263 411 9.7E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 5 407 1.0E-168 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 247 1.4E-56 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 Gene3D G3DSA:3.40.47.10 7 260 3.8E-77 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 SUPERFAMILY SSF53901 215 409 8.74E-68 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS10925 484226058cc78fd8acb333e17c19e3d2 411 SUPERFAMILY SSF53901 5 252 5.61E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS10015 a9397264fa37cd003a6fcb3a36411785 167 SUPERFAMILY SSF88946 22 88 1.41E-8 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS10015 a9397264fa37cd003a6fcb3a36411785 167 SUPERFAMILY SSF88659 98 159 2.24E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS10015 a9397264fa37cd003a6fcb3a36411785 167 Pfam PF04542 Sigma-70 region 2 22 77 2.1E-5 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS10015 a9397264fa37cd003a6fcb3a36411785 167 Pfam PF08281 Sigma-70, region 4 101 153 2.0E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS10015 a9397264fa37cd003a6fcb3a36411785 167 Gene3D G3DSA:1.10.1740.10 5 80 6.3E-10 T 28-03-2018 CWM22_RS10015 a9397264fa37cd003a6fcb3a36411785 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 157 1.0E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS10015 a9397264fa37cd003a6fcb3a36411785 167 Gene3D G3DSA:1.10.10.10 87 166 1.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05445 308f48944f7512efc9e15a57f877a1fd 246 SMART SM00382 30 216 7.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05445 308f48944f7512efc9e15a57f877a1fd 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05445 308f48944f7512efc9e15a57f877a1fd 246 Pfam PF00005 ABC transporter 21 169 6.9E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05445 308f48944f7512efc9e15a57f877a1fd 246 PIRSF PIRSF039085 2 245 1.8E-112 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CWM22_RS05445 308f48944f7512efc9e15a57f877a1fd 246 SUPERFAMILY SSF52540 6 239 5.93E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05445 308f48944f7512efc9e15a57f877a1fd 246 Gene3D G3DSA:3.40.50.300 1 243 1.4E-76 T 28-03-2018 CWM22_RS01310 eeb7c0cfe1bba0dc81425aa4f2cbf269 278 Pfam PF04203 Sortase family 88 242 2.7E-6 T 28-03-2018 IPR005754 Sortase family CWM22_RS01310 eeb7c0cfe1bba0dc81425aa4f2cbf269 278 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 10 250 3.3E-60 T 28-03-2018 IPR009835 Sortase B family CWM22_RS01310 eeb7c0cfe1bba0dc81425aa4f2cbf269 278 Gene3D G3DSA:2.40.260.10 66 252 1.0E-43 T 28-03-2018 IPR023365 Sortase domain CWM22_RS01310 eeb7c0cfe1bba0dc81425aa4f2cbf269 278 SUPERFAMILY SSF63817 57 242 3.4E-30 T 28-03-2018 IPR023365 Sortase domain CWM22_RS11440 8e627c4475350eb91864f9cafb4dd244 416 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CWM22_RS11440 8e627c4475350eb91864f9cafb4dd244 416 Gene3D G3DSA:3.40.50.1100 13 163 8.1E-39 T 28-03-2018 CWM22_RS11440 8e627c4475350eb91864f9cafb4dd244 416 TIGRFAM TIGR02079 THD1: threonine dehydratase 6 416 4.0E-179 T 28-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CWM22_RS11440 8e627c4475350eb91864f9cafb4dd244 416 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 323 415 8.4E-27 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CWM22_RS11440 8e627c4475350eb91864f9cafb4dd244 416 Gene3D G3DSA:3.40.50.1100 164 236 6.0E-10 T 28-03-2018 CWM22_RS11440 8e627c4475350eb91864f9cafb4dd244 416 SUPERFAMILY SSF55021 333 410 1.6E-11 T 28-03-2018 CWM22_RS11440 8e627c4475350eb91864f9cafb4dd244 416 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 310 1.8E-77 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWM22_RS11440 8e627c4475350eb91864f9cafb4dd244 416 SUPERFAMILY SSF53686 6 360 4.45E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWM22_RS11440 8e627c4475350eb91864f9cafb4dd244 416 Gene3D G3DSA:3.40.1020.10 237 416 4.5E-34 T 28-03-2018 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 432 2.1E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 388 2.1E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 413 2.1E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 374 2.1E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 SUPERFAMILY SSF55785 85 200 9.9E-12 T 28-03-2018 IPR000014 PAS domain CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 209 273 1.8E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 SMART SM00387 323 435 5.2E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 SMART SM00091 94 160 2.7E-7 T 28-03-2018 IPR000014 PAS domain CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 Gene3D G3DSA:3.30.565.10 294 449 2.3E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 SUPERFAMILY SSF55874 264 433 3.93E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 Pfam PF00989 PAS fold 96 199 9.2E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 SUPERFAMILY SSF47384 195 273 7.26E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 Gene3D G3DSA:3.30.450.20 81 203 1.3E-18 T 28-03-2018 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 91 208 2.1E-6 T 28-03-2018 IPR000014 PAS domain CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 SMART SM00388 208 274 2.0E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 434 2.5E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS08910 96889964a7acd12d9bef9abad126e3c6 449 Gene3D G3DSA:1.10.287.130 204 270 1.7E-15 T 28-03-2018 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 SMART SM01192 139 432 1.4E-212 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 Gene3D G3DSA:3.20.20.120 128 435 6.8E-101 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 430 9.9E-129 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 ProSitePatterns PS00164 Enolase signature. 341 354 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 432 5.4E-206 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 SUPERFAMILY SSF54826 3 138 1.12E-58 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 SMART SM01193 4 134 5.7E-96 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 Hamap MF_00318 Enolase [eno]. 2 418 44.876 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 Pfam PF03952 Enolase, N-terminal domain 4 134 6.8E-61 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 SUPERFAMILY SSF51604 139 433 1.63E-126 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 Gene3D G3DSA:3.30.390.10 3 127 1.2E-53 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 PIRSF PIRSF001400 1 432 3.2E-189 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 PRINTS PR00148 Enolase signature 161 174 2.0E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 PRINTS PR00148 Enolase signature 37 51 2.0E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 PRINTS PR00148 Enolase signature 318 329 2.0E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 PRINTS PR00148 Enolase signature 341 355 2.0E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 PRINTS PR00148 Enolase signature 107 123 2.0E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS04290 2c401b6341e0872948f7d239832dc64c 435 PRINTS PR00148 Enolase signature 370 387 2.0E-46 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWM22_RS09295 3bed020af2806cfbf0629b2dbd05e8ca 233 SUPERFAMILY SSF52540 4 220 1.27E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09295 3bed020af2806cfbf0629b2dbd05e8ca 233 Pfam PF00005 ABC transporter 24 166 1.7E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS09295 3bed020af2806cfbf0629b2dbd05e8ca 233 Gene3D G3DSA:3.40.50.300 1 228 5.0E-63 T 28-03-2018 CWM22_RS09295 3bed020af2806cfbf0629b2dbd05e8ca 233 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS09295 3bed020af2806cfbf0629b2dbd05e8ca 233 SMART SM00382 32 215 4.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS00470 287cdb7f298755448fe696074f6c7030 139 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 136 3.4E-43 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CWM22_RS00470 287cdb7f298755448fe696074f6c7030 139 SUPERFAMILY SSF53098 1 137 1.97E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS00470 287cdb7f298755448fe696074f6c7030 139 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 139 26.452 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CWM22_RS00470 287cdb7f298755448fe696074f6c7030 139 Gene3D G3DSA:3.30.420.140 1 138 6.3E-43 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWM22_RS00470 287cdb7f298755448fe696074f6c7030 139 SMART SM00732 1 103 1.3E-39 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWM22_RS00470 287cdb7f298755448fe696074f6c7030 139 Pfam PF03652 Holliday junction resolvase 1 136 3.9E-42 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 Pfam PF00232 Glycosyl hydrolase family 1 4 475 2.4E-130 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 SUPERFAMILY SSF51445 5 476 3.32E-156 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 3.1E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 3.1E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 432 3.1E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 3.1E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 3.1E-17 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 372 380 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWM22_RS11090 ed2b1a4179b58052d3b6abbb7436e0f1 479 Gene3D G3DSA:3.20.20.80 4 479 8.8E-148 T 28-03-2018 CWM22_RS01665 661b3bc4329a6ec7cadea49a715cf22e 279 Pfam PF00149 Calcineurin-like phosphoesterase 46 213 4.0E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWM22_RS01665 661b3bc4329a6ec7cadea49a715cf22e 279 Gene3D G3DSA:3.60.21.10 42 262 1.3E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS01665 661b3bc4329a6ec7cadea49a715cf22e 279 SUPERFAMILY SSF56300 40 274 3.14E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 Pfam PF08455 Bacterial SNF2 helicase associated 215 572 1.7E-47 T 28-03-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 Gene3D G3DSA:3.40.50.10810 553 816 5.0E-48 T 28-03-2018 CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 SMART SM00487 581 761 4.2E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 SUPERFAMILY SSF52540 584 781 2.58E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 SMART SM00490 892 974 4.5E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 Gene3D G3DSA:3.40.50.300 852 1012 2.6E-41 T 28-03-2018 CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 SUPERFAMILY SSF52540 783 1028 1.51E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 Pfam PF00271 Helicase conserved C-terminal domain 863 974 1.6E-22 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 Pfam PF04434 SWIM zinc finger 46 71 1.0E-4 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CWM22_RS10480 476c2e44f8ed5dbf2d88aa0ee4868530 1030 Pfam PF00176 SNF2 family N-terminal domain 603 852 1.1E-43 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CWM22_RS00025 5cb375920cfbb042700de2981f58ec49 119 Gene3D G3DSA:1.10.10.60 1 27 3.9E-9 T 28-03-2018 CWM22_RS00025 5cb375920cfbb042700de2981f58ec49 119 Gene3D G3DSA:3.30.1190.10 28 92 2.6E-18 T 28-03-2018 CWM22_RS00025 5cb375920cfbb042700de2981f58ec49 119 SUPERFAMILY SSF47413 2 70 6.97E-21 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS00025 5cb375920cfbb042700de2981f58ec49 119 SMART SM00530 7 62 4.5E-19 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS00025 5cb375920cfbb042700de2981f58ec49 119 Pfam PF01381 Helix-turn-helix 8 62 1.1E-19 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS13195 31383bc7a4a61775203c442111807dc5 341 Gene3D G3DSA:3.90.550.10 6 232 1.2E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS13195 31383bc7a4a61775203c442111807dc5 341 SUPERFAMILY SSF53448 7 234 6.88E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS13195 31383bc7a4a61775203c442111807dc5 341 Pfam PF00535 Glycosyl transferase family 2 9 139 8.6E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS02060 8aa562c9463dd2ccad0b237486958075 293 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 133 144 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWM22_RS02060 8aa562c9463dd2ccad0b237486958075 293 SUPERFAMILY SSF51569 1 293 1.06E-95 T 28-03-2018 CWM22_RS02060 8aa562c9463dd2ccad0b237486958075 293 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 293 1.6E-122 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CWM22_RS02060 8aa562c9463dd2ccad0b237486958075 293 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 292 2.2E-95 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWM22_RS02060 8aa562c9463dd2ccad0b237486958075 293 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWM22_RS02060 8aa562c9463dd2ccad0b237486958075 293 PIRSF PIRSF001359 1 293 3.1E-115 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWM22_RS02060 8aa562c9463dd2ccad0b237486958075 293 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 293 5.1E-92 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWM22_RS02060 8aa562c9463dd2ccad0b237486958075 293 Gene3D G3DSA:3.20.20.70 1 293 1.6E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS03630 38a95bf0a264c1663f82442b16e1aa0f 229 Gene3D G3DSA:3.90.550.10 1 229 3.2E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS03630 38a95bf0a264c1663f82442b16e1aa0f 229 PIRSF PIRSF037382 1 229 2.9E-89 T 28-03-2018 IPR017189 CTP:phosphocholine cytidylyltransferase CWM22_RS03630 38a95bf0a264c1663f82442b16e1aa0f 229 Pfam PF12804 MobA-like NTP transferase domain 3 89 3.7E-11 T 28-03-2018 IPR025877 MobA-like NTP transferase CWM22_RS03630 38a95bf0a264c1663f82442b16e1aa0f 229 SUPERFAMILY SSF53448 1 225 1.56E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS03435 9bca64a175fd8080723140e0d08696b4 306 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 148 3.3E-38 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWM22_RS03435 9bca64a175fd8080723140e0d08696b4 306 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 301 2.7E-82 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWM22_RS03435 9bca64a175fd8080723140e0d08696b4 306 Gene3D G3DSA:3.40.50.720 1 174 2.1E-25 T 28-03-2018 CWM22_RS03435 9bca64a175fd8080723140e0d08696b4 306 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 300 1.5E-36 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWM22_RS03435 9bca64a175fd8080723140e0d08696b4 306 SUPERFAMILY SSF51735 1 133 1.67E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS03435 9bca64a175fd8080723140e0d08696b4 306 Gene3D G3DSA:1.10.1040.10 176 305 8.3E-34 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWM22_RS03435 9bca64a175fd8080723140e0d08696b4 306 SUPERFAMILY SSF48179 177 301 2.41E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWM22_RS03865 6e8e6bcb6ad1d8fa6306901f6a07c33a 343 Gene3D G3DSA:1.10.8.60 146 223 1.6E-7 T 28-03-2018 CWM22_RS03865 6e8e6bcb6ad1d8fa6306901f6a07c33a 343 Gene3D G3DSA:1.20.272.10 224 343 6.5E-26 T 28-03-2018 CWM22_RS03865 6e8e6bcb6ad1d8fa6306901f6a07c33a 343 Gene3D G3DSA:3.40.50.300 4 143 1.8E-15 T 28-03-2018 CWM22_RS03865 6e8e6bcb6ad1d8fa6306901f6a07c33a 343 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 341 3.1E-74 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CWM22_RS03865 6e8e6bcb6ad1d8fa6306901f6a07c33a 343 Pfam PF06144 DNA polymerase III, delta subunit 20 192 1.9E-44 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CWM22_RS03865 6e8e6bcb6ad1d8fa6306901f6a07c33a 343 SUPERFAMILY SSF48019 216 341 2.55E-20 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWM22_RS03865 6e8e6bcb6ad1d8fa6306901f6a07c33a 343 SUPERFAMILY SSF52540 3 210 1.73E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 226 372 1.5E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 7 457 34.016 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 Pfam PF10396 GTP-binding protein TrmE N-terminus 8 126 2.3E-39 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 SUPERFAMILY SSF116878 128 227 1.57E-48 T 28-03-2018 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 SUPERFAMILY SSF116878 382 457 1.57E-48 T 28-03-2018 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 SUPERFAMILY SSF52540 81 169 3.56E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 SUPERFAMILY SSF52540 204 372 3.56E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 Pfam PF01926 50S ribosome-binding GTPase 227 338 3.1E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 Pfam PF12631 MnmE helical domain 129 454 1.3E-57 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 Gene3D G3DSA:3.30.1360.120 1 127 4.6E-43 T 28-03-2018 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 Gene3D G3DSA:1.20.120.430 128 288 1.1E-29 T 28-03-2018 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 14 457 8.9E-131 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CWM22_RS04625 0b59d0ee3fda61ec9ed528fd3c4d69ab 457 Gene3D G3DSA:1.20.120.430 289 457 1.2E-32 T 28-03-2018 CWM22_RS11335 95c3db76c049bb27493e526061f59398 146 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 4 125 3.5E-33 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CWM22_RS11335 95c3db76c049bb27493e526061f59398 146 SUPERFAMILY SSF52540 19 116 3.03E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11335 95c3db76c049bb27493e526061f59398 146 Gene3D G3DSA:3.40.50.300 1 145 8.8E-44 T 28-03-2018 CWM22_RS11335 95c3db76c049bb27493e526061f59398 146 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 4 130 1.9E-34 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 SUPERFAMILY SSF54211 4 186 6.45E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 Gene3D G3DSA:3.30.70.890 182 308 1.3E-34 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 Pfam PF00288 GHMP kinases N terminal domain 87 149 4.4E-17 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 PRINTS PR00959 Mevalonate kinase family signature 135 154 1.1E-22 T 28-03-2018 CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 PRINTS PR00959 Mevalonate kinase family signature 7 31 1.1E-22 T 28-03-2018 CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 PRINTS PR00959 Mevalonate kinase family signature 92 114 1.1E-22 T 28-03-2018 CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 PRINTS PR00959 Mevalonate kinase family signature 264 281 1.1E-22 T 28-03-2018 CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 8 279 3.2E-83 T 28-03-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 SUPERFAMILY SSF55060 171 307 1.8E-34 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 Pfam PF08544 GHMP kinases C terminal 219 296 4.7E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 Gene3D G3DSA:3.30.230.10 1 42 2.4E-6 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS01820 28b5f488cf18c2fc0760d5a67f0d4cf0 311 Gene3D G3DSA:3.30.230.10 43 181 3.9E-27 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 Pfam PF08305 NPCBM/NEW2 domain 222 384 1.1E-20 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 Pfam PF08305 NPCBM/NEW2 domain 30 192 7.3E-18 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 Gene3D G3DSA:2.60.220.10 815 977 2.1E-39 T 28-03-2018 CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 SUPERFAMILY SSF49785 221 388 4.25E-45 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 Pfam PF08306 Glycosyl hydrolase family 98 398 719 2.2E-78 T 28-03-2018 IPR013191 Glycosyl hydrolase family 98, central domain KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 SUPERFAMILY SSF49785 31 193 2.55E-40 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 Gene3D G3DSA:3.20.20.80 401 724 9.4E-110 T 28-03-2018 CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 Pfam PF08307 Glycosyl hydrolase family 98 C-terminal domain 722 978 3.1E-71 T 28-03-2018 IPR013190 Glycosyl hydrolase family 98, C-terminal KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 SMART SM00776 219 386 2.0E-34 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 SMART SM00776 27 194 6.5E-32 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CWM22_RS06255 d2f42ec29beeda318524d47450bcd439 979 Gene3D G3DSA:3.30.2330.20 725 812 4.9E-34 T 28-03-2018 CWM22_RS01740 5fbb917b4912aa0b28a5796fc3ffd83a 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 5.2E-19 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS01740 5fbb917b4912aa0b28a5796fc3ffd83a 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.84 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS01740 5fbb917b4912aa0b28a5796fc3ffd83a 60 SUPERFAMILY SSF57829 2 54 3.66E-16 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWM22_RS01740 5fbb917b4912aa0b28a5796fc3ffd83a 60 Pfam PF01783 Ribosomal L32p protein family 2 54 1.5E-18 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 12 377 2.5E-113 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 47 68 6.1E-5 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 166 184 6.1E-5 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 74 94 6.1E-5 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 SUPERFAMILY SSF55035 108 212 1.78E-32 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 Gene3D G3DSA:3.90.770.10 1 114 3.2E-25 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 2 377 3.6E-101 T 28-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 Gene3D G3DSA:3.90.770.10 206 381 3.8E-37 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 SUPERFAMILY SSF56542 221 418 2.88E-107 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 SUPERFAMILY SSF56542 2 116 2.88E-107 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03005 a793411f00d526c9b2f25198c8babd26 428 Gene3D G3DSA:3.30.70.420 115 205 1.1E-30 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWM22_RS03310 e005aa2754d5b1c455a23c5d89786d24 229 Gene3D G3DSA:3.40.50.1580 1 229 4.6E-55 T 28-03-2018 CWM22_RS03310 e005aa2754d5b1c455a23c5d89786d24 229 Pfam PF01048 Phosphorylase superfamily 2 226 4.4E-45 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWM22_RS03310 e005aa2754d5b1c455a23c5d89786d24 229 SUPERFAMILY SSF53167 1 227 3.4E-71 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWM22_RS03310 e005aa2754d5b1c455a23c5d89786d24 229 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 226 1.9E-61 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWM22_RS02505 329a697b2280c90a6cb7db8a21fa09f9 231 PIRSF PIRSF031509 1 231 2.3E-74 T 28-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 CWM22_RS02505 329a697b2280c90a6cb7db8a21fa09f9 231 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 115 228 4.5E-36 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CWM22_RS04210 2423d57c99714ad40ca602048b404d36 314 Gene3D G3DSA:3.90.1640.10 1 193 5.0E-45 T 28-03-2018 CWM22_RS04210 2423d57c99714ad40ca602048b404d36 314 SUPERFAMILY SSF64182 14 308 2.22E-72 T 28-03-2018 CWM22_RS04210 2423d57c99714ad40ca602048b404d36 314 Pfam PF02272 DHHA1 domain 187 307 7.6E-8 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWM22_RS04210 2423d57c99714ad40ca602048b404d36 314 Pfam PF01368 DHH family 17 152 4.3E-15 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWM22_RS04260 96ce2df9f4ed12446aaf08af48bbbf4d 211 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 89 99 8.7E-5 T 28-03-2018 CWM22_RS04260 96ce2df9f4ed12446aaf08af48bbbf4d 211 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 163 182 8.7E-5 T 28-03-2018 CWM22_RS04260 96ce2df9f4ed12446aaf08af48bbbf4d 211 Gene3D G3DSA:3.40.50.1000 63 208 1.2E-27 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS04260 96ce2df9f4ed12446aaf08af48bbbf4d 211 Gene3D G3DSA:1.10.150.210 17 62 3.2E-24 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CWM22_RS04260 96ce2df9f4ed12446aaf08af48bbbf4d 211 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 3 208 5.2E-78 T 28-03-2018 CWM22_RS04260 96ce2df9f4ed12446aaf08af48bbbf4d 211 SUPERFAMILY SSF56784 4 209 6.14E-51 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS04260 96ce2df9f4ed12446aaf08af48bbbf4d 211 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 176 2.5E-34 T 28-03-2018 CWM22_RS04260 96ce2df9f4ed12446aaf08af48bbbf4d 211 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 173 1.6E-24 T 28-03-2018 CWM22_RS04670 9b009d6d382124e39bb110bdc818751d 118 Gene3D G3DSA:3.40.30.10 1 116 1.1E-22 T 28-03-2018 CWM22_RS04670 9b009d6d382124e39bb110bdc818751d 118 SUPERFAMILY SSF52833 4 110 5.22E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS04670 9b009d6d382124e39bb110bdc818751d 118 Pfam PF03960 ArsC family 57 106 3.6E-7 T 28-03-2018 IPR006660 Arsenate reductase-like CWM22_RS02260 922c08a9fc987074195ebb516f5eb07a 169 Pfam PF00857 Isochorismatase family 3 134 1.1E-33 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWM22_RS02260 922c08a9fc987074195ebb516f5eb07a 169 Gene3D G3DSA:3.40.50.850 1 163 2.7E-38 T 28-03-2018 CWM22_RS02260 922c08a9fc987074195ebb516f5eb07a 169 SUPERFAMILY SSF52499 2 159 8.63E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWM22_RS07605 aa388b5db1ec5473ed6146e76315f585 275 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 220 227 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CWM22_RS07605 aa388b5db1ec5473ed6146e76315f585 275 Pfam PF00800 Prephenate dehydratase 3 179 2.9E-57 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CWM22_RS07605 aa388b5db1ec5473ed6146e76315f585 275 Gene3D G3DSA:3.30.70.260 184 273 2.7E-20 T 28-03-2018 CWM22_RS07605 aa388b5db1ec5473ed6146e76315f585 275 SUPERFAMILY SSF53850 1 180 1.04E-51 T 28-03-2018 CWM22_RS07605 aa388b5db1ec5473ed6146e76315f585 275 Gene3D G3DSA:3.40.190.10 1 90 8.1E-31 T 28-03-2018 CWM22_RS07605 aa388b5db1ec5473ed6146e76315f585 275 SUPERFAMILY SSF55021 173 269 1.96E-20 T 28-03-2018 CWM22_RS07605 aa388b5db1ec5473ed6146e76315f585 275 Gene3D G3DSA:3.40.190.10 91 168 4.8E-21 T 28-03-2018 CWM22_RS13240 1ed0a828ff97699ce47ef17c7284ce47 451 SUPERFAMILY SSF48024 8 119 6.02E-34 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWM22_RS13240 1ed0a828ff97699ce47ef17c7284ce47 451 SUPERFAMILY SSF52540 183 437 7.78E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13240 1ed0a828ff97699ce47ef17c7284ce47 451 Gene3D G3DSA:1.10.860.10 2 151 2.9E-39 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CWM22_RS13240 1ed0a828ff97699ce47ef17c7284ce47 451 Pfam PF03796 DnaB-like helicase C terminal domain 185 443 2.0E-107 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CWM22_RS13240 1ed0a828ff97699ce47ef17c7284ce47 451 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 445 4.2E-165 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CWM22_RS13240 1ed0a828ff97699ce47ef17c7284ce47 451 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 1.2E-30 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWM22_RS13240 1ed0a828ff97699ce47ef17c7284ce47 451 Gene3D G3DSA:3.40.50.300 167 451 2.0E-69 T 28-03-2018 CWM22_RS08175 7685030f520f0bc4b7e63a56ef33fa88 179 PRINTS PR00125 ATP synthase delta subunit signature 137 152 7.4E-7 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08175 7685030f520f0bc4b7e63a56ef33fa88 179 PRINTS PR00125 ATP synthase delta subunit signature 152 170 7.4E-7 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08175 7685030f520f0bc4b7e63a56ef33fa88 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 9 176 3.0E-27 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08175 7685030f520f0bc4b7e63a56ef33fa88 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 9 174 3.7E-18 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08175 7685030f520f0bc4b7e63a56ef33fa88 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 4 179 15.041 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08175 7685030f520f0bc4b7e63a56ef33fa88 179 SUPERFAMILY SSF47928 6 106 1.29E-6 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08175 7685030f520f0bc4b7e63a56ef33fa88 179 Gene3D G3DSA:1.10.520.20 3 149 2.6E-5 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS13245 a512c76537e6555256129c7c291813b5 150 Gene3D G3DSA:3.10.430.100 63 149 3.3E-25 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CWM22_RS13245 a512c76537e6555256129c7c291813b5 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 148 1.2E-25 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CWM22_RS13245 a512c76537e6555256129c7c291813b5 150 SUPERFAMILY SSF55653 57 149 7.19E-24 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CWM22_RS13245 a512c76537e6555256129c7c291813b5 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 22.988 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS13245 a512c76537e6555256129c7c291813b5 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 1.2E-39 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS13245 a512c76537e6555256129c7c291813b5 150 Gene3D G3DSA:3.40.5.10 1 49 6.1E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS13245 a512c76537e6555256129c7c291813b5 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS13245 a512c76537e6555256129c7c291813b5 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 8.0E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS13245 a512c76537e6555256129c7c291813b5 150 SUPERFAMILY SSF55658 1 56 2.62E-15 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CWM22_RS02355 51fd6dd799524bf3938fc2e4b2b48036 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 30.822 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWM22_RS02355 51fd6dd799524bf3938fc2e4b2b48036 238 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 60.256 T 28-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN CWM22_RS02355 51fd6dd799524bf3938fc2e4b2b48036 238 Gene3D G3DSA:3.30.70.980 178 236 1.3E-7 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWM22_RS02355 51fd6dd799524bf3938fc2e4b2b48036 238 Gene3D G3DSA:3.30.70.980 80 174 5.5E-27 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWM22_RS02355 51fd6dd799524bf3938fc2e4b2b48036 238 Gene3D G3DSA:1.10.10.200 2 76 4.7E-24 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CWM22_RS02355 51fd6dd799524bf3938fc2e4b2b48036 238 Pfam PF01709 Transcriptional regulator 4 235 6.6E-81 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWM22_RS02355 51fd6dd799524bf3938fc2e4b2b48036 238 SUPERFAMILY SSF75625 1 236 4.84E-80 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWM22_RS02355 51fd6dd799524bf3938fc2e4b2b48036 238 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 5.5E-68 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWM22_RS05940 9b453a1d92377a0d1c120f2e402ef188 481 Hamap MF_00484 Glycogen synthase [glgA]. 4 479 42.203 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CWM22_RS05940 9b453a1d92377a0d1c120f2e402ef188 481 Pfam PF08323 Starch synthase catalytic domain 6 240 9.0E-78 T 28-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CWM22_RS05940 9b453a1d92377a0d1c120f2e402ef188 481 Pfam PF00534 Glycosyl transferases group 1 289 425 1.8E-12 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWM22_RS05940 9b453a1d92377a0d1c120f2e402ef188 481 Gene3D G3DSA:3.40.50.2000 262 475 6.6E-37 T 28-03-2018 CWM22_RS05940 9b453a1d92377a0d1c120f2e402ef188 481 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 5 479 1.0E-166 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CWM22_RS05940 9b453a1d92377a0d1c120f2e402ef188 481 Gene3D G3DSA:3.40.50.2000 2 261 1.6E-6 T 28-03-2018 CWM22_RS05940 9b453a1d92377a0d1c120f2e402ef188 481 SUPERFAMILY SSF53756 6 481 1.92E-123 T 28-03-2018 CWM22_RS10390 3785a1b3682138116c1b7db4fe807459 243 Gene3D G3DSA:1.10.150.130 1 83 5.1E-8 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWM22_RS10390 3785a1b3682138116c1b7db4fe807459 243 SUPERFAMILY SSF56349 3 233 9.42E-18 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS10390 3785a1b3682138116c1b7db4fe807459 243 Gene3D G3DSA:1.10.443.10 94 241 2.9E-13 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS10390 3785a1b3682138116c1b7db4fe807459 243 Pfam PF00589 Phage integrase family 114 234 4.8E-7 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS10390 3785a1b3682138116c1b7db4fe807459 243 Hamap MF_01817 Tyrosine recombinase XerD-like. 1 243 36.665 T 28-03-2018 IPR020876 Tyrosine recombinase XerD-like GO:0005737 CWM22_RS08810 e0c343c6d5b67cb580a9647c5d63d204 108 Gene3D G3DSA:1.10.10.60 3 32 4.0E-4 T 28-03-2018 CWM22_RS08810 e0c343c6d5b67cb580a9647c5d63d204 108 Gene3D G3DSA:1.10.10.10 33 68 5.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08810 e0c343c6d5b67cb580a9647c5d63d204 108 SUPERFAMILY SSF46689 3 97 3.31E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS08810 e0c343c6d5b67cb580a9647c5d63d204 108 Pfam PF01710 Transposase 1 106 3.2E-22 T 28-03-2018 IPR002622 Transposase, Synechocystis PCC 6803 CWM22_RS08810 e0c343c6d5b67cb580a9647c5d63d204 108 Gene3D G3DSA:1.10.10.60 69 103 0.0033 T 28-03-2018 CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 Gene3D G3DSA:3.40.50.300 5 177 2.2E-26 T 28-03-2018 CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 327 5.4E-141 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 Gene3D G3DSA:1.10.10.10 258 328 8.4E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 169.93 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 SUPERFAMILY SSF52540 21 252 2.18E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 SMART SM00382 52 186 8.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 1.4E-31 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 SUPERFAMILY SSF46785 258 329 1.18E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 3.4E-115 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 333 3.0E-42 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CWM22_RS00380 914d0fa896bff486616f0116bc1b9894 333 Gene3D G3DSA:1.10.8.60 185 255 1.3E-30 T 28-03-2018 CWM22_RS10760 29dc06d9988f2785509ff37f78499370 229 SUPERFAMILY SSF52317 26 227 2.66E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS10760 29dc06d9988f2785509ff37f78499370 229 Gene3D G3DSA:3.40.50.880 1 228 1.5E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS10760 29dc06d9988f2785509ff37f78499370 229 Pfam PF07722 Peptidase C26 5 209 1.0E-60 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 186 197 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 Gene3D G3DSA:3.20.20.60 257 576 2.2E-99 T 28-03-2018 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 451 466 1.8E-32 T 28-03-2018 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 504 516 1.8E-32 T 28-03-2018 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 295 314 1.8E-32 T 28-03-2018 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 468 483 1.8E-32 T 28-03-2018 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 451 469 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 Gene3D G3DSA:3.50.30.10 138 256 1.2E-27 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 227 1.5E-21 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 569 3.5E-224 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 SUPERFAMILY SSF52009 127 242 1.18E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 PIRSF PIRSF000732 1 577 2.5E-209 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 128 1.1E-30 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 Gene3D G3DSA:1.10.274.10 26 137 3.7E-36 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 545 5.0E-129 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 SUPERFAMILY SSF47831 24 145 1.05E-34 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CWM22_RS08305 6666ef62a3d87c34332560333491c741 577 SUPERFAMILY SSF51621 251 553 3.93E-109 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 Gene3D G3DSA:3.50.50.60 238 324 2.6E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 7.7E-11 T 28-03-2018 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.7E-11 T 28-03-2018 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 7.7E-11 T 28-03-2018 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 7.7E-11 T 28-03-2018 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 Gene3D G3DSA:3.50.50.60 96 237 3.9E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 Gene3D G3DSA:3.50.50.60 1 95 5.8E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 SUPERFAMILY SSF51905 1 313 1.2E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 SUPERFAMILY SSF55424 322 438 2.58E-13 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 3.6E-17 T 28-03-2018 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 3.6E-17 T 28-03-2018 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 3.6E-17 T 28-03-2018 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.6E-17 T 28-03-2018 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 Gene3D G3DSA:3.30.390.30 325 441 8.3E-5 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWM22_RS07465 ef8bf6c45f2d786188231c35b4453bc6 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 302 1.5E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS02125 4baf24d16bf3627edad1a4e7e84c3efe 404 SUPERFAMILY SSF53383 7 402 3.4E-92 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS02125 4baf24d16bf3627edad1a4e7e84c3efe 404 Pfam PF00155 Aminotransferase class I and II 35 385 3.1E-48 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWM22_RS02125 4baf24d16bf3627edad1a4e7e84c3efe 404 Gene3D G3DSA:3.40.640.10 53 280 2.3E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS02125 4baf24d16bf3627edad1a4e7e84c3efe 404 Gene3D G3DSA:3.90.1150.10 281 404 1.6E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS02185 b5f92552d5195ff070c602314f5bc491 966 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 448 737 2.2E-33 T 28-03-2018 IPR027607 SEC10/PgrA surface exclusion domain CWM22_RS02185 b5f92552d5195ff070c602314f5bc491 966 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 933 964 2.8E-7 T 28-03-2018 CWM22_RS02185 b5f92552d5195ff070c602314f5bc491 966 Pfam PF00746 LPXTG cell wall anchor motif 931 964 1.1E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS02185 b5f92552d5195ff070c602314f5bc491 966 Gene3D G3DSA:1.10.287.620 804 875 4.7E-5 T 28-03-2018 CWM22_RS02185 b5f92552d5195ff070c602314f5bc491 966 Gene3D G3DSA:1.10.287.620 174 334 1.6E-12 T 28-03-2018 CWM22_RS02185 b5f92552d5195ff070c602314f5bc491 966 Gene3D G3DSA:1.10.287.620 631 803 4.6E-9 T 28-03-2018 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 SUPERFAMILY SSF57783 3 96 1.7E-33 T 28-03-2018 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 Pfam PF08275 DNA primase catalytic core, N-terminal domain 125 255 7.5E-35 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 Gene3D G3DSA:3.90.980.10 107 243 2.5E-36 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 SUPERFAMILY SSF56731 113 425 1.22E-91 T 28-03-2018 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 PIRSF PIRSF002811 1 596 1.7E-171 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 SMART SM00493 262 333 1.7E-16 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 Pfam PF01807 CHC2 zinc finger 3 96 3.4E-36 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 TIGRFAM TIGR01391 dnaG: DNA primase 3 416 1.2E-138 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 Gene3D G3DSA:3.90.580.10 1 98 3.1E-32 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 Hamap MF_00974 DNA primase [dnaG]. 1 570 26.624 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 Pfam PF13155 Toprim-like 265 348 2.2E-17 T 28-03-2018 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 Gene3D G3DSA:3.40.1360.20 258 371 5.3E-33 T 28-03-2018 CWM22_RS04775 284ddcef9ed8b00f2739ff3eda8ee803 596 SMART SM00400 33 87 3.2E-32 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWM22_RS00955 573288cb863533ca49157de8a5ae69ea 573 SUPERFAMILY SSF53098 363 509 7.59E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS00955 573288cb863533ca49157de8a5ae69ea 573 Pfam PF01609 Transposase DDE domain 227 497 4.0E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS00955 573288cb863533ca49157de8a5ae69ea 573 Gene3D G3DSA:3.90.350.10 163 479 8.6E-43 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS08625 573288cb863533ca49157de8a5ae69ea 573 SUPERFAMILY SSF53098 363 509 7.59E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS08625 573288cb863533ca49157de8a5ae69ea 573 Pfam PF01609 Transposase DDE domain 227 497 4.0E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS08625 573288cb863533ca49157de8a5ae69ea 573 Gene3D G3DSA:3.90.350.10 163 479 8.6E-43 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS11565 573288cb863533ca49157de8a5ae69ea 573 SUPERFAMILY SSF53098 363 509 7.59E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS11565 573288cb863533ca49157de8a5ae69ea 573 Pfam PF01609 Transposase DDE domain 227 497 4.0E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS11565 573288cb863533ca49157de8a5ae69ea 573 Gene3D G3DSA:3.90.350.10 163 479 8.6E-43 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS01410 573288cb863533ca49157de8a5ae69ea 573 SUPERFAMILY SSF53098 363 509 7.59E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS01410 573288cb863533ca49157de8a5ae69ea 573 Pfam PF01609 Transposase DDE domain 227 497 4.0E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS01410 573288cb863533ca49157de8a5ae69ea 573 Gene3D G3DSA:3.90.350.10 163 479 8.6E-43 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS02750 573288cb863533ca49157de8a5ae69ea 573 SUPERFAMILY SSF53098 363 509 7.59E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS02750 573288cb863533ca49157de8a5ae69ea 573 Pfam PF01609 Transposase DDE domain 227 497 4.0E-11 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS02750 573288cb863533ca49157de8a5ae69ea 573 Gene3D G3DSA:3.90.350.10 163 479 8.6E-43 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS04330 5bddd07a56c2de198e773527da515710 552 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 429 3.6E-151 T 28-03-2018 CWM22_RS04330 5bddd07a56c2de198e773527da515710 552 Gene3D G3DSA:3.40.970.40 235 276 5.6E-9 T 28-03-2018 CWM22_RS04330 5bddd07a56c2de198e773527da515710 552 Gene3D G3DSA:2.30.310.10 1 167 8.7E-53 T 28-03-2018 CWM22_RS04330 5bddd07a56c2de198e773527da515710 552 Pfam PF05670 Domain of unknown function (DUF814) 436 521 8.0E-23 T 28-03-2018 IPR008532 Domain of unknown function DUF814 CWM22_RS11265 c2b8030430a4984d7201697c17e235ea 112 Gene3D G3DSA:3.30.1330.30 16 112 1.8E-18 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWM22_RS11265 c2b8030430a4984d7201697c17e235ea 112 SUPERFAMILY SSF55315 17 111 7.61E-24 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWM22_RS11265 c2b8030430a4984d7201697c17e235ea 112 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 106 9.2E-15 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 PIRSF PIRSF500176 1 319 1.2E-93 T 28-03-2018 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 Gene3D G3DSA:3.40.50.1170 1 200 5.8E-53 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 PIRSF PIRSF001220 1 318 7.4E-94 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 SUPERFAMILY SSF53774 1 317 6.93E-95 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 Pfam PF00710 Asparaginase, N-terminal 3 187 1.7E-55 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 77 87 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 PRINTS PR00139 Asparaginase/glutaminase family signature 76 94 1.3E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 PRINTS PR00139 Asparaginase/glutaminase family signature 249 267 1.3E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.3E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 Gene3D G3DSA:3.40.50.40 201 319 1.7E-25 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CWM22_RS02105 7397da44eaaaf494038491e3ceb0c8f7 319 SMART SM00870 3 314 1.4E-131 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 342 37.316 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 118 1.0E-32 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 SMART SM00859 4 119 1.7E-43 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 Gene3D G3DSA:3.30.360.10 139 325 6.4E-66 T 28-03-2018 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 SUPERFAMILY SSF55347 127 329 3.57E-68 T 28-03-2018 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 5 342 6.4E-134 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 PIRSF PIRSF000148 2 347 6.9E-123 T 28-03-2018 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 137 328 3.5E-53 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 Gene3D G3DSA:3.40.50.720 2 138 3.0E-33 T 28-03-2018 CWM22_RS07480 24efdf3c0abdb20eaf4019b42c14892e 358 SUPERFAMILY SSF51735 5 155 4.57E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS10955 04ad0b133872fb447b16afe376073a17 144 Pfam PF01047 MarR family 33 91 8.9E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS10955 04ad0b133872fb447b16afe376073a17 144 Gene3D G3DSA:1.10.10.10 5 126 9.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10955 04ad0b133872fb447b16afe376073a17 144 SMART SM00347 26 126 7.1E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS10955 04ad0b133872fb447b16afe376073a17 144 SUPERFAMILY SSF46785 11 142 1.21E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10955 04ad0b133872fb447b16afe376073a17 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 4.3E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS10955 04ad0b133872fb447b16afe376073a17 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 4.3E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS10955 04ad0b133872fb447b16afe376073a17 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 4.3E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS10955 04ad0b133872fb447b16afe376073a17 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 4.3E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 PIRSF PIRSF000102 4 321 7.2E-104 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 SUPERFAMILY SSF51735 4 148 2.32E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 Gene3D G3DSA:3.40.50.720 8 146 5.1E-32 T 28-03-2018 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 SUPERFAMILY SSF56327 147 315 3.75E-54 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 9 146 8.9E-46 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 317 4.8E-39 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 7 316 44.638 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 Gene3D G3DSA:3.90.110.10 147 319 4.2E-49 T 28-03-2018 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 4.0E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 PRINTS PR00086 L-lactate dehydrogenase signature 34 58 4.0E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 4.0E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 PRINTS PR00086 L-lactate dehydrogenase signature 9 33 4.0E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 4.0E-48 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWM22_RS05135 e61de52c7c98755a3a4893be02588e79 327 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 12 310 3.8E-123 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CWM22_RS01735 730ff54406fcf7615d7f35d1ea9e2a42 49 Pfam PF00471 Ribosomal protein L33 3 49 2.5E-18 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS01735 730ff54406fcf7615d7f35d1ea9e2a42 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS01735 730ff54406fcf7615d7f35d1ea9e2a42 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.0E-17 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS01735 730ff54406fcf7615d7f35d1ea9e2a42 49 SUPERFAMILY SSF57829 1 49 2.08E-15 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWM22_RS01735 730ff54406fcf7615d7f35d1ea9e2a42 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 15.717 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 Gene3D G3DSA:3.60.21.10 102 461 5.3E-80 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 PRINTS PR01607 Apyrase family signature 619 638 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 PRINTS PR01607 Apyrase family signature 380 400 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 PRINTS PR01607 Apyrase family signature 113 131 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 PRINTS PR01607 Apyrase family signature 518 541 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 PRINTS PR01607 Apyrase family signature 307 324 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 PRINTS PR01607 Apyrase family signature 335 358 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 796 825 2.8E-5 T 28-03-2018 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 Pfam PF00149 Calcineurin-like phosphoesterase 116 352 1.0E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 Pfam PF02872 5'-nucleotidase, C-terminal domain 447 637 2.3E-22 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 SUPERFAMILY SSF55816 448 680 1.26E-40 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 ProSitePatterns PS00786 5'-nucleotidase signature 2. 201 212 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 SUPERFAMILY SSF56300 110 445 1.9E-79 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS12755 c8fd2f321568b957337ce7a36af28f76 827 Gene3D G3DSA:3.90.780.10 462 682 1.1E-45 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 Gene3D G3DSA:3.90.1260.10 157 351 1.7E-82 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 115 126 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 SUPERFAMILY SSF69864 169 396 4.32E-93 T 28-03-2018 CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 395 54.434 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 Gene3D G3DSA:1.20.5.470 361 394 6.7E-11 T 28-03-2018 CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 SUPERFAMILY SSF52402 1 169 1.63E-43 T 28-03-2018 CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 Gene3D G3DSA:3.40.50.620 4 156 3.1E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 392 7.4E-161 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS12235 a73892a7465e72b0eb3f0cc2aa0a687a 397 Pfam PF00764 Arginosuccinate synthase 7 390 1.5E-172 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS04430 ec7de8f55922dfda26072418e6027272 543 SUPERFAMILY SSF53448 1 257 5.34E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04430 ec7de8f55922dfda26072418e6027272 543 SUPERFAMILY SSF53448 267 397 1.5E-14 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04430 ec7de8f55922dfda26072418e6027272 543 Gene3D G3DSA:3.90.550.10 267 531 3.8E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04430 ec7de8f55922dfda26072418e6027272 543 Pfam PF01501 Glycosyl transferase family 8 2 239 7.8E-38 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CWM22_RS04430 ec7de8f55922dfda26072418e6027272 543 Gene3D G3DSA:3.90.550.10 1 266 7.4E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04430 ec7de8f55922dfda26072418e6027272 543 Pfam PF00535 Glycosyl transferase family 2 270 392 2.7E-9 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 174 197 8.8E-84 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 268 287 8.8E-84 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 312 334 8.8E-84 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 110 133 8.8E-84 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 148 173 8.8E-84 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 19 37 8.8E-84 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 367 385 8.8E-84 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 68 88 8.8E-84 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 401 419 8.8E-84 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 Hamap MF_01465 Protein translocase subunit SecY [secY]. 6 432 26.032 T 28-03-2018 IPR026593 Protein translocase subunit SecY CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 Pfam PF00344 SecY translocase 69 414 2.2E-96 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 ProSitePatterns PS00755 Protein secY signature 1. 69 88 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 Gene3D G3DSA:1.10.3370.10 1 436 8.7E-130 T 28-03-2018 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 16 428 6.0E-127 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 PIRSF PIRSF004557 2 436 2.2E-113 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWM22_RS00595 e0abcd2bbbcd914e2262f0ede1238114 436 SUPERFAMILY SSF103491 5 423 4.84E-114 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWM22_RS08655 91aeda69d250af2581df0ca6c040428d 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 279 1.3E-47 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWM22_RS08655 91aeda69d250af2581df0ca6c040428d 295 Gene3D G3DSA:1.10.3470.10 1 284 3.1E-54 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS06520 f3335309aeb69677e7e8df1bb53df6b1 129 Gene3D G3DSA:1.10.10.10 4 128 3.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10730 ddaf696601cd0fc29e3293838de606cf 234 Pfam PF03483 B3/4 domain 74 215 1.6E-23 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWM22_RS10730 ddaf696601cd0fc29e3293838de606cf 234 SUPERFAMILY SSF56037 50 227 2.51E-30 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWM22_RS10730 ddaf696601cd0fc29e3293838de606cf 234 Gene3D G3DSA:3.50.40.10 56 229 2.3E-28 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWM22_RS10730 ddaf696601cd0fc29e3293838de606cf 234 SMART SM00873 64 217 7.4E-8 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWM22_RS05010 8ef5e10a1d072a242691b695392ee832 245 SUPERFAMILY SSF81324 8 207 2.86E-41 T 28-03-2018 CWM22_RS05010 8ef5e10a1d072a242691b695392ee832 245 Gene3D G3DSA:1.20.120.350 4 128 3.2E-8 T 28-03-2018 CWM22_RS05010 8ef5e10a1d072a242691b695392ee832 245 Gene3D G3DSA:1.10.287.70 129 215 7.3E-24 T 28-03-2018 CWM22_RS05010 8ef5e10a1d072a242691b695392ee832 245 Pfam PF07885 Ion channel 138 206 2.1E-20 T 28-03-2018 IPR013099 Potassium channel domain CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 Gene3D G3DSA:3.30.420.40 195 266 3.5E-5 T 28-03-2018 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 Gene3D G3DSA:3.30.420.40 267 348 3.6E-17 T 28-03-2018 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 SMART SM00842 7 194 7.3E-84 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 Pfam PF14450 Cell division protein FtsA 206 365 1.2E-19 T 28-03-2018 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 Gene3D G3DSA:3.30.420.40 1 186 3.2E-31 T 28-03-2018 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 Pfam PF02491 SHS2 domain inserted in FTSA 85 158 3.7E-20 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 1.5E-98 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 SUPERFAMILY SSF53067 197 365 3.43E-40 T 28-03-2018 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 SUPERFAMILY SSF53067 6 195 3.78E-55 T 28-03-2018 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 Pfam PF11983 Membrane-attachment and polymerisation-promoting switch 377 459 6.5E-18 T 28-03-2018 IPR021873 Cell division protein FtsA, C-terminal CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 458 28.069 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CWM22_RS02810 5f81bfbe95bc9230c77a8b2c43246906 459 PIRSF PIRSF003101 1 458 9.3E-128 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CWM22_RS06620 e696276bb30565fbb8bae7adc0d71c1b 75 Pfam PF11372 Domain of unknown function (DUF3173) 2 73 5.6E-26 T 28-03-2018 IPR021512 Protein of unknown function DUF3173 CWM22_RS06630 bc8ca649c354e925d4183aeb631fbff9 249 Gene3D G3DSA:3.40.50.1000 99 249 8.6E-24 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS06630 bc8ca649c354e925d4183aeb631fbff9 249 SUPERFAMILY SSF56784 1 248 2.86E-32 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS06630 bc8ca649c354e925d4183aeb631fbff9 249 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 218 1.5E-22 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS06630 bc8ca649c354e925d4183aeb631fbff9 249 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 129 213 1.8E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS05835 b908569ea9f0473f2076c0cb04cec939 227 Gene3D G3DSA:1.10.10.10 126 227 3.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05835 b908569ea9f0473f2076c0cb04cec939 227 SMART SM00862 151 225 6.8E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS05835 b908569ea9f0473f2076c0cb04cec939 227 SUPERFAMILY SSF52172 1 178 3.42E-35 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS05835 b908569ea9f0473f2076c0cb04cec939 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 224 9.7E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS05835 b908569ea9f0473f2076c0cb04cec939 227 Gene3D G3DSA:3.40.50.2300 1 125 6.0E-32 T 28-03-2018 CWM22_RS05835 b908569ea9f0473f2076c0cb04cec939 227 SMART SM00448 2 112 2.5E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS05835 b908569ea9f0473f2076c0cb04cec939 227 Pfam PF00072 Response regulator receiver domain 4 112 4.7E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 Gene3D G3DSA:2.20.110.10 59 140 4.0E-21 T 28-03-2018 CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 SMART SM00698 125 140 56.0 T 28-03-2018 IPR003409 MORN motif CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 SMART SM00698 79 100 1.1E-5 T 28-03-2018 IPR003409 MORN motif CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 SMART SM00698 102 123 1.9 T 28-03-2018 IPR003409 MORN motif CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 SMART SM00698 56 77 18.0 T 28-03-2018 IPR003409 MORN motif CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 Pfam PF02493 MORN repeat 58 80 3.5E-4 T 28-03-2018 IPR003409 MORN motif CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 Pfam PF02493 MORN repeat 81 102 2.1E-7 T 28-03-2018 IPR003409 MORN motif CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 Pfam PF02493 MORN repeat 104 120 0.0022 T 28-03-2018 IPR003409 MORN motif CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 SUPERFAMILY SSF82185 53 138 6.15E-21 T 28-03-2018 CWM22_RS10340 b3a4189742f6f602d082507e009b25a0 140 PIRSF PIRSF034300 1 140 1.9E-64 T 28-03-2018 IPR014590 Uncharacterised conserved protein MORN repeat-containing CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 Pfam PF00293 NUDIX domain 8 132 7.2E-23 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 PRINTS PR01402 Mutator MutX protein signature 72 98 4.1E-61 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 PRINTS PR01402 Mutator MutX protein signature 102 122 4.1E-61 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 PRINTS PR01402 Mutator MutX protein signature 8 26 4.1E-61 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 PRINTS PR01402 Mutator MutX protein signature 139 159 4.1E-61 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 PRINTS PR01402 Mutator MutX protein signature 26 41 4.1E-61 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 PRINTS PR01402 Mutator MutX protein signature 122 139 4.1E-61 T 28-03-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 SUPERFAMILY SSF55811 5 153 2.71E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 Gene3D G3DSA:3.90.79.10 2 156 6.2E-31 T 28-03-2018 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 PRINTS PR00502 NUDIX hydrolase family signature 37 51 2.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 PRINTS PR00502 NUDIX hydrolase family signature 51 66 2.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWM22_RS08035 7ce3bf382a627149f358e22cad1706be 160 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWM22_RS04965 d0614fe83e31a7e90e81030d75a37851 271 Gene3D G3DSA:3.40.50.1000 1 271 5.1E-47 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS04965 d0614fe83e31a7e90e81030d75a37851 271 ProSitePatterns PS01229 Hypothetical cof family signature 2. 218 240 - T 28-03-2018 CWM22_RS04965 d0614fe83e31a7e90e81030d75a37851 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 264 1.8E-64 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS04965 d0614fe83e31a7e90e81030d75a37851 271 SUPERFAMILY SSF56784 1 269 4.85E-69 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS04965 d0614fe83e31a7e90e81030d75a37851 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 264 2.9E-59 T 28-03-2018 IPR000150 Cof family GO:0016787 CWM22_RS04965 d0614fe83e31a7e90e81030d75a37851 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 237 9.6E-29 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWM22_RS04965 d0614fe83e31a7e90e81030d75a37851 271 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 Gene3D G3DSA:1.10.3210.10 332 513 2.5E-24 T 28-03-2018 CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 SMART SM00471 349 455 1.3E-13 T 28-03-2018 IPR003607 HD/PDEase domain CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 SUPERFAMILY SSF54791 225 321 2.31E-15 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 SUPERFAMILY SSF109604 337 491 3.59E-29 T 28-03-2018 CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 Pfam PF00013 KH domain 229 284 9.2E-7 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 SMART SM00322 225 292 3.8E-6 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 Pfam PF12072 Domain of unknown function (DUF3552) 5 222 1.2E-42 T 28-03-2018 IPR022711 Ribonuclease Y, N-terminal CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 Gene3D G3DSA:3.30.1370.10 222 321 2.5E-9 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 TIGRFAM TIGR00277 HDIG: HDIG domain 349 426 4.7E-24 T 28-03-2018 IPR006675 HDIG domain CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 7 537 3.8E-228 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 Pfam PF01966 HD domain 354 445 1.1E-18 T 28-03-2018 IPR006674 HD domain CWM22_RS02465 f93c34228d59038fb213d0fcfffbaf44 537 Hamap MF_00335 Ribonuclease Y [rny]. 4 537 24.941 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CWM22_RS10260 7d718f4511e7156c29065bed4ea34e1b 370 SUPERFAMILY SSF102114 96 307 1.57E-15 T 28-03-2018 CWM22_RS10260 7d718f4511e7156c29065bed4ea34e1b 370 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 2 349 70.365 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS10260 7d718f4511e7156c29065bed4ea34e1b 370 Pfam PF04055 Radical SAM superfamily 105 278 1.4E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWM22_RS10260 7d718f4511e7156c29065bed4ea34e1b 370 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 1 351 2.6E-133 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS10260 7d718f4511e7156c29065bed4ea34e1b 370 Gene3D G3DSA:3.20.20.70 12 363 1.9E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS10260 7d718f4511e7156c29065bed4ea34e1b 370 Pfam PF13394 4Fe-4S single cluster domain 110 201 2.3E-7 T 28-03-2018 CWM22_RS10260 7d718f4511e7156c29065bed4ea34e1b 370 PIRSF PIRSF006004 1 363 2.0E-136 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS07490 b855fd78616bfbd0dca102cf30bb2cb0 364 Gene3D G3DSA:3.40.50.1970 7 158 4.0E-30 T 28-03-2018 CWM22_RS07490 b855fd78616bfbd0dca102cf30bb2cb0 364 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 348 1.6E-62 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWM22_RS07490 b855fd78616bfbd0dca102cf30bb2cb0 364 PIRSF PIRSF000112 1 360 8.1E-98 T 28-03-2018 CWM22_RS07490 b855fd78616bfbd0dca102cf30bb2cb0 364 Gene3D G3DSA:1.20.1090.10 159 363 1.1E-37 T 28-03-2018 CWM22_RS07490 b855fd78616bfbd0dca102cf30bb2cb0 364 SUPERFAMILY SSF56796 1 359 9.81E-90 T 28-03-2018 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 10 436 3.8E-110 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 Gene3D G3DSA:1.10.940.10 3 146 8.1E-29 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 Gene3D G3DSA:3.40.50.150 231 437 7.7E-51 T 28-03-2018 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 Gene3D G3DSA:1.10.287.150 154 190 0.0014 T 28-03-2018 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 318 329 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 Pfam PF01189 16S rRNA methyltransferase RsmB/F 241 434 8.7E-54 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 Pfam PF01029 NusB family 8 128 5.4E-29 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 319 331 8.0E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 251 261 8.0E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 222 236 8.0E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 418 435 8.0E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 369 385 8.0E-30 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 SUPERFAMILY SSF48013 7 130 4.97E-33 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWM22_RS02490 49e6c80be782f9d1cc28ee35b4964d03 437 SUPERFAMILY SSF53335 143 436 6.25E-62 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS11295 a68ca2e5b3dadd2091eaab483f7a57be 264 Gene3D G3DSA:3.90.1200.10 37 260 6.8E-22 T 28-03-2018 CWM22_RS11295 a68ca2e5b3dadd2091eaab483f7a57be 264 Pfam PF01636 Phosphotransferase enzyme family 44 215 2.3E-14 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CWM22_RS11295 a68ca2e5b3dadd2091eaab483f7a57be 264 SUPERFAMILY SSF56112 12 225 4.89E-25 T 28-03-2018 IPR011009 Protein kinase-like domain CWM22_RS12435 8fa9673201ad1a3593f5abc70343ca42 225 Pfam PF01694 Rhomboid family 55 190 2.5E-32 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CWM22_RS12435 8fa9673201ad1a3593f5abc70343ca42 225 Gene3D G3DSA:1.20.1540.10 6 191 5.0E-36 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CWM22_RS12435 8fa9673201ad1a3593f5abc70343ca42 225 SUPERFAMILY SSF144091 7 194 8.63E-39 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CWM22_RS04200 76d4039c21bf107b67f333c7c5b97214 89 SUPERFAMILY SSF57716 2 89 4.99E-25 T 28-03-2018 CWM22_RS04200 76d4039c21bf107b67f333c7c5b97214 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 5.2E-23 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS04200 76d4039c21bf107b67f333c7c5b97214 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 22.465 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CWM22_RS04200 76d4039c21bf107b67f333c7c5b97214 89 Gene3D G3DSA:4.10.830.10 1 89 5.0E-29 T 28-03-2018 CWM22_RS01725 676a1a62a2c52d20c4a6c29b213eb35b 267 Gene3D G3DSA:1.20.1330.10 4 227 1.3E-5 T 28-03-2018 CWM22_RS10570 9536688cec22937e0171ee2d5ef8b25d 447 Pfam PF00271 Helicase conserved C-terminal domain 239 337 1.1E-24 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS10570 9536688cec22937e0171ee2d5ef8b25d 447 Gene3D G3DSA:3.40.50.300 219 447 2.5E-40 T 28-03-2018 CWM22_RS10570 9536688cec22937e0171ee2d5ef8b25d 447 SUPERFAMILY SSF52540 69 357 1.04E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10570 9536688cec22937e0171ee2d5ef8b25d 447 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 1 435 51.386 T 28-03-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 CWM22_RS10570 9536688cec22937e0171ee2d5ef8b25d 447 Pfam PF00270 DEAD/DEAH box helicase 25 191 1.8E-44 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWM22_RS10570 9536688cec22937e0171ee2d5ef8b25d 447 SMART SM00490 256 337 4.9E-28 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS10570 9536688cec22937e0171ee2d5ef8b25d 447 Gene3D G3DSA:3.40.50.300 4 218 2.5E-51 T 28-03-2018 CWM22_RS10570 9536688cec22937e0171ee2d5ef8b25d 447 SMART SM00487 20 220 5.0E-51 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS09725 a89faf758cc1ce5b4d781f3959102e9e 209 Pfam PF01844 HNH endonuclease 131 179 5.4E-8 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CWM22_RS09725 a89faf758cc1ce5b4d781f3959102e9e 209 Gene3D G3DSA:3.40.1800.10 110 190 4.6E-12 T 28-03-2018 CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 SUPERFAMILY SSF52540 292 521 2.19E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 Gene3D G3DSA:3.40.50.300 286 537 3.1E-64 T 28-03-2018 CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 Pfam PF12558 ATP-binding cassette cobalt transporter 236 303 1.2E-12 T 28-03-2018 IPR022216 ABC cobalt transporter GO:0016820 CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 SMART SM00382 31 223 2.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 SMART SM00382 320 504 4.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 Gene3D G3DSA:3.40.50.300 1 242 4.7E-56 T 28-03-2018 CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 ProSitePatterns PS00211 ABC transporters family signature. 428 442 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 SUPERFAMILY SSF52540 4 235 6.95E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 Pfam PF00005 ABC transporter 311 456 4.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 Pfam PF00005 ABC transporter 22 172 2.3E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS02400 61176492af7f45dd6b59cd114c2aef24 557 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS02530 7e32dd3ae4ab82cc723e6ad2d4f72772 308 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 304 7.3E-126 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CWM22_RS02530 7e32dd3ae4ab82cc723e6ad2d4f72772 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 293 4.2E-64 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWM22_RS02530 7e32dd3ae4ab82cc723e6ad2d4f72772 308 Gene3D G3DSA:3.40.50.1100 142 307 3.6E-49 T 28-03-2018 CWM22_RS02530 7e32dd3ae4ab82cc723e6ad2d4f72772 308 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CWM22_RS02530 7e32dd3ae4ab82cc723e6ad2d4f72772 308 Gene3D G3DSA:3.40.50.1100 38 141 7.9E-41 T 28-03-2018 CWM22_RS02530 7e32dd3ae4ab82cc723e6ad2d4f72772 308 SUPERFAMILY SSF53686 2 304 1.44E-95 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWM22_RS02530 7e32dd3ae4ab82cc723e6ad2d4f72772 308 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 304 2.3E-131 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CWM22_RS07410 0a30deee048d068579ca02847b770b14 403 Gene3D G3DSA:1.10.3290.10 60 319 1.8E-33 T 28-03-2018 IPR003812 Fido domain CWM22_RS07410 0a30deee048d068579ca02847b770b14 403 Pfam PF02661 Fic/DOC family 148 248 4.4E-14 T 28-03-2018 IPR003812 Fido domain CWM22_RS07410 0a30deee048d068579ca02847b770b14 403 Gene3D G3DSA:1.10.10.10 328 399 1.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07410 0a30deee048d068579ca02847b770b14 403 SUPERFAMILY SSF140931 133 311 7.06E-23 T 28-03-2018 IPR003812 Fido domain CWM22_RS02200 0bf7fd9d654ee97f61f59b90a5acbc95 332 Gene3D G3DSA:3.40.50.2300 60 161 4.8E-8 T 28-03-2018 CWM22_RS02200 0bf7fd9d654ee97f61f59b90a5acbc95 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.2E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS02200 0bf7fd9d654ee97f61f59b90a5acbc95 332 Gene3D G3DSA:3.40.50.2300 162 332 5.7E-36 T 28-03-2018 CWM22_RS02200 0bf7fd9d654ee97f61f59b90a5acbc95 332 Gene3D G3DSA:1.10.260.40 2 59 3.6E-14 T 28-03-2018 CWM22_RS02200 0bf7fd9d654ee97f61f59b90a5acbc95 332 SUPERFAMILY SSF53822 61 320 1.35E-43 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS02200 0bf7fd9d654ee97f61f59b90a5acbc95 332 SUPERFAMILY SSF47413 2 51 1.79E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS02200 0bf7fd9d654ee97f61f59b90a5acbc95 332 SMART SM00354 1 71 2.7E-9 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS02200 0bf7fd9d654ee97f61f59b90a5acbc95 332 Pfam PF13377 Periplasmic binding protein-like domain 163 331 2.4E-32 T 28-03-2018 CWM22_RS05650 2babdeb388b297cf9839bb6164cde105 94 SUPERFAMILY SSF57783 12 46 2.55E-7 T 28-03-2018 CWM22_RS05650 2babdeb388b297cf9839bb6164cde105 94 Gene3D G3DSA:3.30.65.10 2 54 3.3E-11 T 28-03-2018 CWM22_RS05650 2babdeb388b297cf9839bb6164cde105 94 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 10 39 4.7E-11 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWM22_RS06480 2babdeb388b297cf9839bb6164cde105 94 SUPERFAMILY SSF57783 12 46 2.55E-7 T 28-03-2018 CWM22_RS06480 2babdeb388b297cf9839bb6164cde105 94 Gene3D G3DSA:3.30.65.10 2 54 3.3E-11 T 28-03-2018 CWM22_RS06480 2babdeb388b297cf9839bb6164cde105 94 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 10 39 4.7E-11 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWM22_RS05760 2babdeb388b297cf9839bb6164cde105 94 SUPERFAMILY SSF57783 12 46 2.55E-7 T 28-03-2018 CWM22_RS05760 2babdeb388b297cf9839bb6164cde105 94 Gene3D G3DSA:3.30.65.10 2 54 3.3E-11 T 28-03-2018 CWM22_RS05760 2babdeb388b297cf9839bb6164cde105 94 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 10 39 4.7E-11 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWM22_RS05535 2babdeb388b297cf9839bb6164cde105 94 SUPERFAMILY SSF57783 12 46 2.55E-7 T 28-03-2018 CWM22_RS05535 2babdeb388b297cf9839bb6164cde105 94 Gene3D G3DSA:3.30.65.10 2 54 3.3E-11 T 28-03-2018 CWM22_RS05535 2babdeb388b297cf9839bb6164cde105 94 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 10 39 4.7E-11 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 127 3.3E-12 T 28-03-2018 CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 Gene3D G3DSA:3.30.230.10 214 326 3.1E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 307 9.4E-104 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 SUPERFAMILY SSF118116 442 631 5.1E-51 T 28-03-2018 CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 SMART SM01340 209 327 5.7E-55 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 210 326 3.0E-37 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 SUPERFAMILY SSF54211 191 327 3.3E-36 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 Pfam PF08676 MutL C terminal dimerisation domain 446 589 7.0E-41 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 SMART SM00853 447 589 4.0E-44 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 Gene3D G3DSA:3.30.565.10 1 199 1.2E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 SUPERFAMILY SSF55874 3 214 2.23E-55 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS00425 b6ee1c9c46aa16fdb5130e67784769a0 645 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 629 27.862 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CWM22_RS10860 2887002abb32904b3dc8cdb30787da50 222 Gene3D G3DSA:1.10.3290.10 2 217 1.8E-45 T 28-03-2018 IPR003812 Fido domain CWM22_RS10860 2887002abb32904b3dc8cdb30787da50 222 Pfam PF02661 Fic/DOC family 74 171 8.8E-23 T 28-03-2018 IPR003812 Fido domain CWM22_RS10860 2887002abb32904b3dc8cdb30787da50 222 SUPERFAMILY SSF140931 49 214 1.06E-36 T 28-03-2018 IPR003812 Fido domain CWM22_RS06175 4595cec836da258589f8657563b3d5b4 471 Pfam PF11798 IMS family HHH motif 223 255 4.5E-7 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CWM22_RS06175 4595cec836da258589f8657563b3d5b4 471 Pfam PF11799 impB/mucB/samB family C-terminal domain 295 403 1.4E-16 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWM22_RS06175 4595cec836da258589f8657563b3d5b4 471 Gene3D G3DSA:3.30.70.270 109 217 2.3E-15 T 28-03-2018 CWM22_RS06175 4595cec836da258589f8657563b3d5b4 471 SUPERFAMILY SSF100879 303 398 2.16E-9 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWM22_RS06175 4595cec836da258589f8657563b3d5b4 471 Pfam PF00817 impB/mucB/samB family 17 207 8.8E-15 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWM22_RS06175 4595cec836da258589f8657563b3d5b4 471 Gene3D G3DSA:3.30.1490.100 303 414 1.7E-21 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWM22_RS06175 4595cec836da258589f8657563b3d5b4 471 SUPERFAMILY SSF56672 4 83 1.96E-48 T 28-03-2018 CWM22_RS06175 4595cec836da258589f8657563b3d5b4 471 SUPERFAMILY SSF56672 116 292 1.96E-48 T 28-03-2018 CWM22_RS06175 4595cec836da258589f8657563b3d5b4 471 Gene3D G3DSA:1.10.150.20 221 302 5.4E-17 T 28-03-2018 CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 SUPERFAMILY SSF51430 2 266 5.63E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 Pfam PF00248 Aldo/keto reductase family 14 266 1.6E-52 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 Gene3D G3DSA:3.20.20.100 1 275 2.5E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 PRINTS PR00069 Aldo-keto reductase signature 91 109 2.2E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 PRINTS PR00069 Aldo-keto reductase signature 35 59 2.2E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 PRINTS PR00069 Aldo-keto reductase signature 131 148 2.2E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 PRINTS PR00069 Aldo-keto reductase signature 202 226 2.2E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 PRINTS PR00069 Aldo-keto reductase signature 165 194 2.2E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 PIRSF PIRSF000097 1 279 7.4E-70 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS03140 9f34cf196deed8caac33cad18968be6c 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 131 148 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWM22_RS00885 00cada3ed2ed900ff00db66d2f67837b 316 PIRSF PIRSF028757 1 315 4.3E-69 T 28-03-2018 IPR003507 Peptidase family S66 CWM22_RS00885 00cada3ed2ed900ff00db66d2f67837b 316 SUPERFAMILY SSF52317 2 165 1.33E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS00885 00cada3ed2ed900ff00db66d2f67837b 316 Pfam PF02016 LD-carboxypeptidase 10 306 1.2E-64 T 28-03-2018 IPR003507 Peptidase family S66 CWM22_RS00885 00cada3ed2ed900ff00db66d2f67837b 316 SUPERFAMILY SSF141986 163 310 1.44E-32 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CWM22_RS00885 00cada3ed2ed900ff00db66d2f67837b 316 Gene3D G3DSA:3.50.30.60 161 316 4.0E-32 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CWM22_RS00885 00cada3ed2ed900ff00db66d2f67837b 316 Gene3D G3DSA:3.40.50.10740 1 160 3.8E-46 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CWM22_RS07150 05f4d847fdf1f71d1145188385c35670 90 Pfam PF00886 Ribosomal protein S16 9 67 1.2E-25 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07150 05f4d847fdf1f71d1145188385c35670 90 Gene3D G3DSA:3.30.1320.10 2 85 2.0E-34 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07150 05f4d847fdf1f71d1145188385c35670 90 SUPERFAMILY SSF54565 2 86 4.84E-34 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07150 05f4d847fdf1f71d1145188385c35670 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 4.6E-35 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07150 05f4d847fdf1f71d1145188385c35670 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.299 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11020 d9e70601f1185894c419894a8dcd5d70 130 Pfam PF03780 Asp23 family, cell envelope-related function 6 108 1.8E-29 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CWM22_RS10240 8a162d97286f6620efcf2aba3544dbf2 486 Gene3D G3DSA:3.20.140.10 8 387 3.5E-124 T 28-03-2018 CWM22_RS10240 8a162d97286f6620efcf2aba3544dbf2 486 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 155 335 9.7E-9 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CWM22_RS10240 8a162d97286f6620efcf2aba3544dbf2 486 SUPERFAMILY SSF54675 8 138 7.36E-47 T 28-03-2018 CWM22_RS10240 8a162d97286f6620efcf2aba3544dbf2 486 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 10 465 2.2E-186 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CWM22_RS10240 8a162d97286f6620efcf2aba3544dbf2 486 SUPERFAMILY SSF51690 139 478 1.34E-129 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CWM22_RS10240 8a162d97286f6620efcf2aba3544dbf2 486 PIRSF PIRSF000484 5 480 7.9E-150 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CWM22_RS13340 07f455297f8347df4f4254c22e4610bb 179 PIRSF PIRSF000847 1 179 2.0E-49 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CWM22_RS13340 07f455297f8347df4f4254c22e4610bb 179 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 73 2.9E-16 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CWM22_RS13340 07f455297f8347df4f4254c22e4610bb 179 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 5 168 1.8E-53 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CWM22_RS13340 07f455297f8347df4f4254c22e4610bb 179 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 51 73 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CWM22_RS07535 3cae7eb33ef42ceb00c4e78632fb56f1 258 SUPERFAMILY SSF102114 28 232 3.53E-20 T 28-03-2018 CWM22_RS07535 3cae7eb33ef42ceb00c4e78632fb56f1 258 ProSitePatterns PS01087 Radical activating enzymes signature. 19 40 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CWM22_RS07535 3cae7eb33ef42ceb00c4e78632fb56f1 258 PIRSF PIRSF000371 1 56 1.6E-25 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWM22_RS07535 3cae7eb33ef42ceb00c4e78632fb56f1 258 PIRSF PIRSF000371 53 257 1.9E-54 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWM22_RS07535 3cae7eb33ef42ceb00c4e78632fb56f1 258 Gene3D G3DSA:3.80.30.10 83 258 1.1E-33 T 28-03-2018 CWM22_RS07535 3cae7eb33ef42ceb00c4e78632fb56f1 258 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 56 252 6.5E-60 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CWM22_RS07535 3cae7eb33ef42ceb00c4e78632fb56f1 258 Pfam PF04055 Radical SAM superfamily 26 193 3.4E-25 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWM22_RS07535 3cae7eb33ef42ceb00c4e78632fb56f1 258 Pfam PF13353 4Fe-4S single cluster domain 18 139 3.2E-13 T 28-03-2018 CWM22_RS12360 12f6a19ff01d6bc78a9510337d185de2 209 TIGRFAM TIGR03608 L_ocin_972_ABC: putative bacteriocin export ABC transporter, lactococcin 972 group 4 209 1.3E-87 T 28-03-2018 IPR019895 Putative bacteriocin export ABC transporter, lactococcin 972 group CWM22_RS12360 12f6a19ff01d6bc78a9510337d185de2 209 SMART SM00382 26 209 3.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS12360 12f6a19ff01d6bc78a9510337d185de2 209 Pfam PF00005 ABC transporter 17 165 2.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS12360 12f6a19ff01d6bc78a9510337d185de2 209 Gene3D G3DSA:3.40.50.300 1 209 5.6E-63 T 28-03-2018 CWM22_RS12360 12f6a19ff01d6bc78a9510337d185de2 209 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS12360 12f6a19ff01d6bc78a9510337d185de2 209 SUPERFAMILY SSF52540 2 209 6.66E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10360 799751ed2ffddbc78252e21a90b42bf9 181 PIRSF PIRSF029256 14 170 2.4E-59 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CWM22_RS10360 799751ed2ffddbc78252e21a90b42bf9 181 SUPERFAMILY SSF75217 16 168 1.37E-39 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWM22_RS10360 799751ed2ffddbc78252e21a90b42bf9 181 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 15 167 34.223 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CWM22_RS10360 799751ed2ffddbc78252e21a90b42bf9 181 Pfam PF00588 SpoU rRNA Methylase family 15 158 2.0E-32 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CWM22_RS10360 799751ed2ffddbc78252e21a90b42bf9 181 Gene3D G3DSA:3.40.1280.10 13 179 4.2E-36 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWM22_RS03570 95db1ba7726b2455430834cd6b02e75c 372 Gene3D G3DSA:3.40.50.2000 188 351 4.3E-8 T 28-03-2018 CWM22_RS03570 95db1ba7726b2455430834cd6b02e75c 372 SUPERFAMILY SSF53756 16 283 2.51E-10 T 28-03-2018 CWM22_RS00815 4a835e01d0c672b8d92cb2cd4158631e 234 Pfam PF00005 ABC transporter 19 165 8.4E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS00815 4a835e01d0c672b8d92cb2cd4158631e 234 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS00815 4a835e01d0c672b8d92cb2cd4158631e 234 SUPERFAMILY SSF52540 3 215 4.11E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00815 4a835e01d0c672b8d92cb2cd4158631e 234 Gene3D G3DSA:3.40.50.300 2 227 2.5E-52 T 28-03-2018 CWM22_RS00815 4a835e01d0c672b8d92cb2cd4158631e 234 SMART SM00382 28 215 3.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS03485 ed0c093575e9be002fcc6d120031ae9f 212 SMART SM00849 12 194 2.6E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS03485 ed0c093575e9be002fcc6d120031ae9f 212 SUPERFAMILY SSF56281 12 211 2.49E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS03485 ed0c093575e9be002fcc6d120031ae9f 212 Pfam PF00753 Metallo-beta-lactamase superfamily 12 178 6.3E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS03485 ed0c093575e9be002fcc6d120031ae9f 212 Gene3D G3DSA:3.60.15.10 11 212 1.4E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS02790 de6d861c38e0b6445d6d66349255d7fd 354 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 336 1.0E-25 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWM22_RS02790 de6d861c38e0b6445d6d66349255d7fd 354 Gene3D G3DSA:3.40.50.2000 164 344 4.4E-21 T 28-03-2018 CWM22_RS02790 de6d861c38e0b6445d6d66349255d7fd 354 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 352 23.326 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWM22_RS02790 de6d861c38e0b6445d6d66349255d7fd 354 Gene3D G3DSA:3.40.50.2000 1 163 1.3E-25 T 28-03-2018 CWM22_RS02790 de6d861c38e0b6445d6d66349255d7fd 354 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 143 1.7E-39 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWM22_RS02790 de6d861c38e0b6445d6d66349255d7fd 354 SUPERFAMILY SSF53756 2 347 7.71E-79 T 28-03-2018 CWM22_RS02760 6774c74be39ff4085a5c644dc419f3ee 352 SUPERFAMILY SSF142906 101 236 7.98E-29 T 28-03-2018 CWM22_RS02760 6774c74be39ff4085a5c644dc419f3ee 352 Pfam PF04237 YjbR 119 214 1.6E-12 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CWM22_RS04665 7a505e9e55f416f4a07c345fe0f01c83 403 PIRSF PIRSF001491 3 403 1.6E-150 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWM22_RS04665 7a505e9e55f416f4a07c345fe0f01c83 403 Gene3D G3DSA:3.40.720.10 282 402 6.4E-12 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWM22_RS04665 7a505e9e55f416f4a07c345fe0f01c83 403 SUPERFAMILY SSF143856 108 226 2.88E-47 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWM22_RS04665 7a505e9e55f416f4a07c345fe0f01c83 403 Hamap MF_00740 Phosphopentomutase [deoB]. 4 399 53.676 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWM22_RS04665 7a505e9e55f416f4a07c345fe0f01c83 403 TIGRFAM TIGR01696 deoB: phosphopentomutase 6 396 5.5E-157 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWM22_RS04665 7a505e9e55f416f4a07c345fe0f01c83 403 Pfam PF01676 Metalloenzyme superfamily 5 390 6.0E-43 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CWM22_RS04665 7a505e9e55f416f4a07c345fe0f01c83 403 SUPERFAMILY SSF53649 227 402 8.24E-82 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWM22_RS04665 7a505e9e55f416f4a07c345fe0f01c83 403 SUPERFAMILY SSF53649 2 108 8.24E-82 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWM22_RS04665 7a505e9e55f416f4a07c345fe0f01c83 403 Gene3D G3DSA:3.30.70.1250 107 226 5.5E-49 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 7 627 41.413 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 276 290 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 Pfam PF01134 Glucose inhibited division protein A 10 402 1.2E-164 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 9 623 1.4E-272 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.4E-5 T 28-03-2018 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 162 1.4E-5 T 28-03-2018 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 Pfam PF13932 GidA associated domain 404 619 3.1E-73 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 SUPERFAMILY SSF51905 99 264 3.09E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 SUPERFAMILY SSF51905 7 68 3.09E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 Gene3D G3DSA:3.50.50.60 7 268 1.3E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 371 394 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CWM22_RS13255 740a4f8a1522fca44d642a6c854aa290 638 SMART SM01228 549 620 1.4E-39 T 28-03-2018 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 Gene3D G3DSA:1.10.287.110 1 116 1.0E-35 T 28-03-2018 IPR001623 DnaJ domain CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 Gene3D G3DSA:2.10.230.10 145 201 8.5E-16 T 28-03-2018 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 Gene3D G3DSA:2.60.260.20 260 366 4.6E-25 T 28-03-2018 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 SUPERFAMILY SSF57938 135 215 1.7E-19 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 SMART SM00271 4 61 2.3E-30 T 28-03-2018 IPR001623 DnaJ domain CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 PRINTS PR00625 DnaJ domain signature 25 40 1.2E-31 T 28-03-2018 IPR001623 DnaJ domain CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 PRINTS PR00625 DnaJ domain signature 7 25 1.2E-31 T 28-03-2018 IPR001623 DnaJ domain CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 PRINTS PR00625 DnaJ domain signature 41 61 1.2E-31 T 28-03-2018 IPR001623 DnaJ domain CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 PRINTS PR00625 DnaJ domain signature 61 80 1.2E-31 T 28-03-2018 IPR001623 DnaJ domain CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 SUPERFAMILY SSF49493 264 348 1.83E-21 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 354 1.5E-138 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 SUPERFAMILY SSF49493 115 139 3.14E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 SUPERFAMILY SSF49493 205 267 3.14E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 Gene3D G3DSA:2.60.260.20 202 259 1.9E-19 T 28-03-2018 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 Pfam PF00226 DnaJ domain 6 66 3.4E-26 T 28-03-2018 IPR001623 DnaJ domain CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 SUPERFAMILY SSF46565 1 105 2.62E-35 T 28-03-2018 IPR001623 DnaJ domain CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 Pfam PF01556 DnaJ C terminal domain 122 338 5.4E-40 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 374 39.231 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CWM22_RS01895 725de3e2ce4e4492fb04cea2ff18fffc 378 Pfam PF00684 DnaJ central domain 148 212 2.0E-13 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 SUPERFAMILY SSF144052 6 413 9.81E-138 T 28-03-2018 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 Pfam PF02073 Thermophilic metalloprotease (M29) 7 411 4.1E-160 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 327 348 2.1E-53 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 304 324 2.1E-53 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 159 181 2.1E-53 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 392 411 2.1E-53 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 366 388 2.1E-53 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 17 34 2.1E-53 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 248 267 2.1E-53 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWM22_RS11825 0656f4ff9535b3e19b1c580b3481b9c2 413 Gene3D G3DSA:3.40.1830.10 6 182 1.3E-49 T 28-03-2018 IPR035097 Peptidase M29, N-terminal CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 Gene3D G3DSA:1.10.10.10 208 258 4.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 134 370 2.1E-125 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 SUPERFAMILY SSF88659 211 285 7.66E-22 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 Pfam PF03979 Sigma-70 factor, region 1.1 17 88 1.8E-11 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 5 371 33.616 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 Pfam PF04542 Sigma-70 region 2 138 207 5.5E-23 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 Pfam PF04545 Sigma-70, region 4 306 359 3.6E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 162 175 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 331 357 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 PRINTS PR00046 Major sigma-70 factor signature 186 194 1.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 PRINTS PR00046 Major sigma-70 factor signature 310 322 1.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 PRINTS PR00046 Major sigma-70 factor signature 162 175 1.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 PRINTS PR00046 Major sigma-70 factor signature 331 346 1.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 PRINTS PR00046 Major sigma-70 factor signature 346 357 1.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 SUPERFAMILY SSF88659 268 368 1.66E-28 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 SUPERFAMILY SSF88946 99 208 1.96E-53 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 Pfam PF00140 Sigma-70 factor, region 1.2 100 132 2.0E-14 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 Gene3D G3DSA:1.10.10.10 300 371 6.1E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 134 359 4.6E-38 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 Pfam PF04539 Sigma-70 region 3 217 293 1.4E-30 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS04780 ca6980d60395f49e0a22271a8e5efedf 372 Gene3D G3DSA:1.10.601.10 1 207 1.5E-75 T 28-03-2018 CWM22_RS08885 02babc6f0f03247bda11b311550b0bac 198 Gene3D G3DSA:3.40.1360.10 77 170 1.6E-36 T 28-03-2018 CWM22_RS08885 02babc6f0f03247bda11b311550b0bac 198 Pfam PF02132 RecR protein 40 78 2.1E-16 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CWM22_RS08885 02babc6f0f03247bda11b311550b0bac 198 SMART SM00493 80 165 2.1E-10 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS08885 02babc6f0f03247bda11b311550b0bac 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CWM22_RS08885 02babc6f0f03247bda11b311550b0bac 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 100.521 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CWM22_RS08885 02babc6f0f03247bda11b311550b0bac 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 5.0E-82 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CWM22_RS08885 02babc6f0f03247bda11b311550b0bac 198 SUPERFAMILY SSF111304 1 198 1.96E-73 T 28-03-2018 IPR023627 Recombination protein RecR CWM22_RS08885 02babc6f0f03247bda11b311550b0bac 198 Pfam PF13662 Toprim domain 80 171 1.5E-22 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS11785 9d07dd686ecead4d738679d303fdf2cf 684 Gene3D G3DSA:3.40.50.300 1 246 9.4E-48 T 28-03-2018 CWM22_RS11785 9d07dd686ecead4d738679d303fdf2cf 684 Pfam PF00005 ABC transporter 17 166 2.2E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS11785 9d07dd686ecead4d738679d303fdf2cf 684 Pfam PF02687 FtsX-like permease family 584 676 6.4E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWM22_RS11785 9d07dd686ecead4d738679d303fdf2cf 684 SMART SM00382 26 214 7.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11785 9d07dd686ecead4d738679d303fdf2cf 684 SUPERFAMILY SSF52540 2 215 4.51E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Gene3D G3DSA:3.30.300.20 534 574 0.0022 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Gene3D G3DSA:1.10.10.400 233 318 2.2E-18 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 SUPERFAMILY SSF55666 453 550 1.17E-28 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Gene3D G3DSA:2.40.50.140 627 727 6.9E-24 T 28-03-2018 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Gene3D G3DSA:3.30.230.70 11 232 1.6E-44 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Pfam PF00575 S1 RNA binding domain 622 693 9.2E-19 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 239 323 1.5E-12 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 SUPERFAMILY SSF54211 304 495 2.58E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 SUPERFAMILY SSF55666 143 233 8.38E-29 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 SUPERFAMILY SSF54211 9 142 7.59E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Pfam PF00013 KH domain 560 615 1.3E-8 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Gene3D G3DSA:3.30.230.70 319 533 5.9E-55 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 SUPERFAMILY SSF46915 224 329 3.4E-19 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 SMART SM00316 623 693 5.1E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 PIRSF PIRSF005499 1 727 2.0E-279 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 2 696 28.734 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Pfam PF03725 3' exoribonuclease family, domain 2 462 532 9.9E-8 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Pfam PF03725 3' exoribonuclease family, domain 2 145 207 3.8E-13 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Pfam PF01138 3' exoribonuclease family, domain 1 13 142 3.0E-19 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Pfam PF01138 3' exoribonuclease family, domain 1 326 459 1.0E-14 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 SMART SM00322 555 620 2.9E-11 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 SUPERFAMILY SSF54791 559 643 8.54E-21 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 Gene3D G3DSA:3.30.1370.10 575 626 6.8E-10 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 SUPERFAMILY SSF50249 615 698 5.28E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS11690 54def5c065a375e375691a051d58da8b 739 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 694 2.1E-292 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWM22_RS08520 47f381c15fc5c5ba968d28c68bc7abfa 84 Gene3D G3DSA:1.10.10.60 23 76 4.3E-6 T 28-03-2018 CWM22_RS11550 b1f4669fc9759e4a1fe923ffe3c0cee3 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 4.6E-81 T 28-03-2018 IPR003797 DegV CWM22_RS11550 b1f4669fc9759e4a1fe923ffe3c0cee3 286 SUPERFAMILY SSF82549 2 283 7.85E-80 T 28-03-2018 CWM22_RS11550 b1f4669fc9759e4a1fe923ffe3c0cee3 286 Gene3D G3DSA:3.30.1180.10 158 282 1.7E-34 T 28-03-2018 CWM22_RS11550 b1f4669fc9759e4a1fe923ffe3c0cee3 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 279 1.5E-87 T 28-03-2018 IPR003797 DegV CWM22_RS11550 b1f4669fc9759e4a1fe923ffe3c0cee3 286 Gene3D G3DSA:3.40.50.10170 1 155 2.0E-44 T 28-03-2018 CWM22_RS06865 f86e1ed211c2f586d7f9f2a23d4e0233 419 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 52.524 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWM22_RS06865 f86e1ed211c2f586d7f9f2a23d4e0233 419 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWM22_RS06865 f86e1ed211c2f586d7f9f2a23d4e0233 419 Gene3D G3DSA:3.90.1150.10 275 416 1.8E-51 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS06865 f86e1ed211c2f586d7f9f2a23d4e0233 419 SUPERFAMILY SSF53383 8 417 1.79E-176 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS06865 f86e1ed211c2f586d7f9f2a23d4e0233 419 Gene3D G3DSA:3.40.640.10 37 274 5.1E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS06865 f86e1ed211c2f586d7f9f2a23d4e0233 419 PIRSF PIRSF000412 1 419 1.7E-166 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWM22_RS06865 f86e1ed211c2f586d7f9f2a23d4e0233 419 Pfam PF00464 Serine hydroxymethyltransferase 9 385 2.6E-172 T 28-03-2018 CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 Gene3D G3DSA:3.90.120.10 192 300 5.4E-12 T 28-03-2018 CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 Pfam PF00145 C-5 cytosine-specific DNA methylase 5 208 2.9E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 Pfam PF00145 C-5 cytosine-specific DNA methylase 230 313 2.9E-10 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 67 79 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 294 312 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 111 125 9.0E-12 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 157 170 9.0E-12 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 5 21 9.0E-12 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 Gene3D G3DSA:3.40.50.150 1 191 2.0E-39 T 28-03-2018 CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 SUPERFAMILY SSF53335 3 313 1.41E-57 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06145 1296ba687400d89cdc4e41e2daf45b4b 319 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 6 215 1.1E-37 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS12320 6d26bc5aca915aaef53f620f756af20e 252 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 6 229 5.6E-35 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CWM22_RS12320 6d26bc5aca915aaef53f620f756af20e 252 Gene3D G3DSA:3.60.160.10 1 241 7.6E-56 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CWM22_RS12320 6d26bc5aca915aaef53f620f756af20e 252 SUPERFAMILY SSF51219 6 232 2.56E-63 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CWM22_RS12320 6d26bc5aca915aaef53f620f756af20e 252 Pfam PF01987 Mitochondrial biogenesis AIM24 12 219 6.9E-50 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 Pfam PF00501 AMP-binding enzyme 19 415 5.3E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 Gene3D G3DSA:2.30.38.10 321 408 4.5E-20 T 28-03-2018 CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 14 518 1.5E-227 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 519 270.119 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 28-03-2018 IPR020845 AMP-binding, conserved site CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 SUPERFAMILY SSF56801 13 519 3.01E-117 T 28-03-2018 CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 Gene3D G3DSA:3.30.300.30 409 520 4.9E-23 T 28-03-2018 CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 39 439 1.6E-99 T 28-03-2018 IPR010071 Amino acid adenylation domain CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 Gene3D G3DSA:3.40.50.980 10 162 1.1E-28 T 28-03-2018 CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 Gene3D G3DSA:3.40.50.980 163 320 1.2E-31 T 28-03-2018 CWM22_RS03775 cd357f1009c81e5ea2b489fdeca1cceb 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 507 1.7E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 Gene3D G3DSA:3.40.50.1370 3 164 1.2E-48 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 Gene3D G3DSA:3.40.50.1370 165 305 3.5E-40 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 11 303 4.5E-87 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 301 8.1E-23 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 151 6.4E-32 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 10 305 38.075 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 SUPERFAMILY SSF53671 9 305 2.49E-86 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 1.8E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 42 64 1.8E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 1.8E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 1.8E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 1.8E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 137 154 1.8E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 1.7E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 1.7E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 1.7E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS07180 b666a4bde4277b07355dbc18abe660db 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 1.7E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWM22_RS13290 744f5b409124bf499658cba1f3ea71f7 223 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 5 202 5.9E-72 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWM22_RS13290 744f5b409124bf499658cba1f3ea71f7 223 Gene3D G3DSA:3.30.1330.90 23 146 3.7E-26 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CWM22_RS13290 744f5b409124bf499658cba1f3ea71f7 223 Gene3D G3DSA:3.30.70.260 147 222 2.2E-16 T 28-03-2018 CWM22_RS13290 744f5b409124bf499658cba1f3ea71f7 223 Pfam PF01842 ACT domain 152 214 1.4E-10 T 28-03-2018 IPR002912 ACT domain CWM22_RS13290 744f5b409124bf499658cba1f3ea71f7 223 PIRSF PIRSF036692 4 223 1.6E-107 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWM22_RS13290 744f5b409124bf499658cba1f3ea71f7 223 Pfam PF03315 Serine dehydratase beta chain 8 77 5.9E-12 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWM22_RS13290 744f5b409124bf499658cba1f3ea71f7 223 SUPERFAMILY SSF55021 140 221 2.8E-19 T 28-03-2018 CWM22_RS13290 744f5b409124bf499658cba1f3ea71f7 223 SUPERFAMILY SSF143548 22 141 7.72E-30 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CWM22_RS09460 03c6f5839d0b79350f0dd0b5d30caa71 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 37 161 2.8E-38 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CWM22_RS09460 03c6f5839d0b79350f0dd0b5d30caa71 165 SUPERFAMILY SSF55486 2 164 4.64E-39 T 28-03-2018 CWM22_RS09460 03c6f5839d0b79350f0dd0b5d30caa71 165 Gene3D G3DSA:3.40.390.30 1 165 1.8E-42 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CWM22_RS09460 03c6f5839d0b79350f0dd0b5d30caa71 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 164 21.85 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CWM22_RS09460 03c6f5839d0b79350f0dd0b5d30caa71 165 Pfam PF02130 Uncharacterized protein family UPF0054 13 159 2.1E-40 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CWM22_RS09460 03c6f5839d0b79350f0dd0b5d30caa71 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 130 140 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CWM22_RS10975 172e163207320e3a058f617748d51788 367 Gene3D G3DSA:3.20.20.10 1 226 1.5E-42 T 28-03-2018 IPR029066 PLP-binding barrel CWM22_RS10975 172e163207320e3a058f617748d51788 367 Gene3D G3DSA:2.40.37.10 227 367 1.5E-51 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWM22_RS10975 172e163207320e3a058f617748d51788 367 SMART SM01005 242 367 1.7E-65 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 47 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 SUPERFAMILY SSF51419 13 243 4.07E-62 T 28-03-2018 IPR029066 PLP-binding barrel CWM22_RS10975 172e163207320e3a058f617748d51788 367 Pfam PF00842 Alanine racemase, C-terminal domain 242 365 7.5E-42 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 SUPERFAMILY SSF50621 237 366 1.95E-48 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWM22_RS10975 172e163207320e3a058f617748d51788 367 PRINTS PR00992 Alanine racemase signature 275 290 1.6E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 PRINTS PR00992 Alanine racemase signature 258 273 1.6E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 PRINTS PR00992 Alanine racemase signature 349 362 1.6E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 PRINTS PR00992 Alanine racemase signature 127 139 1.6E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 PRINTS PR00992 Alanine racemase signature 161 172 1.6E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 PRINTS PR00992 Alanine racemase signature 67 85 1.6E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 PRINTS PR00992 Alanine racemase signature 32 48 1.6E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 PRINTS PR00992 Alanine racemase signature 201 228 1.6E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 PRINTS PR00992 Alanine racemase signature 295 312 1.6E-64 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 Hamap MF_01201 Alanine racemase. 6 367 34.055 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 TIGRFAM TIGR00492 alr: alanine racemase 7 366 2.5E-108 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS10975 172e163207320e3a058f617748d51788 367 Pfam PF01168 Alanine racemase, N-terminal domain 13 228 1.4E-61 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Gene3D G3DSA:3.10.20.320 1629 1761 2.6E-8 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Gene3D G3DSA:3.10.20.320 742 872 0.38 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Gene3D G3DSA:3.10.20.320 1003 1123 0.0058 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Gene3D G3DSA:3.10.20.320 1256 1376 0.0056 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Gene3D G3DSA:3.10.20.320 1377 1515 4.7E-8 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Gene3D G3DSA:3.10.20.320 1542 1628 5.8E-5 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 14 49 4.0E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF04650 YSIRK type signal peptide 18 43 1.3E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Gene3D G3DSA:3.10.20.320 873 1002 4.4E-7 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Gene3D G3DSA:3.10.20.320 1885 2009 4.0E-5 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Gene3D G3DSA:3.10.20.320 1124 1255 1.7E-7 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2330 2363 3.0E-4 T 28-03-2018 CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF06458 MucBP domain 1047 1114 0.2 T 28-03-2018 IPR009459 MucBP domain CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF06458 MucBP domain 1382 1494 0.54 T 28-03-2018 IPR009459 MucBP domain CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF06458 MucBP domain 880 990 0.018 T 28-03-2018 IPR009459 MucBP domain CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF06458 MucBP domain 1551 1618 0.028 T 28-03-2018 IPR009459 MucBP domain CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF06458 MucBP domain 1162 1242 0.094 T 28-03-2018 IPR009459 MucBP domain CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF06458 MucBP domain 1633 1746 0.19 T 28-03-2018 IPR009459 MucBP domain CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF06458 MucBP domain 1299 1366 0.32 T 28-03-2018 IPR009459 MucBP domain CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF06458 MucBP domain 1890 1993 0.39 T 28-03-2018 IPR009459 MucBP domain CWM22_RS04735 c84fff34540178503a38e5d03874307d 2367 Pfam PF00746 LPXTG cell wall anchor motif 2325 2365 4.8E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS01910 6a00608488b9a5059eacc76e05a85bd0 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 115 7.2E-32 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWM22_RS01910 6a00608488b9a5059eacc76e05a85bd0 223 Gene3D G3DSA:1.10.3720.10 13 222 4.0E-40 T 28-03-2018 CWM22_RS01910 6a00608488b9a5059eacc76e05a85bd0 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 220 2.5E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS01910 6a00608488b9a5059eacc76e05a85bd0 223 SUPERFAMILY SSF161098 19 206 6.15E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 546 596 3.8E-4 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 704 748 2.3E-4 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 504 521 3.0 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 653 699 5.5E-13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 4 742 0.0 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 SUPERFAMILY SSF56719 27 482 1.57E-164 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Gene3D G3DSA:1.10.268.10 340 482 1.8E-42 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Gene3D G3DSA:3.30.1360.40 232 328 6.6E-34 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 SUPERFAMILY SSF101904 496 815 1.57E-72 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Gene3D G3DSA:2.120.10.90 494 815 4.1E-68 T 28-03-2018 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 467 1.7E-147 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Gene3D G3DSA:3.90.199.10 30 209 3.7E-74 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 3 817 33.525 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWM22_RS07295 a930261e851d6aba66fcf04a500ffb72 817 SMART SM00434 7 460 2.7E-248 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 Gene3D G3DSA:2.70.150.10 2 193 1.9E-33 T 28-03-2018 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 297 303 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 Pfam PF00702 haloacid dehalogenase-like hydrolase 291 544 8.6E-29 T 28-03-2018 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 SUPERFAMILY SSF81665 6 98 3.92E-43 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 SUPERFAMILY SSF81665 579 768 3.92E-43 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 SUPERFAMILY SSF81665 195 289 3.92E-43 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 Gene3D G3DSA:3.40.50.1000 434 592 9.7E-40 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 565 2.1E-20 T 28-03-2018 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 454 464 2.1E-20 T 28-03-2018 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 144 158 2.1E-20 T 28-03-2018 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 549 2.1E-20 T 28-03-2018 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 432 443 2.1E-20 T 28-03-2018 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 295 309 2.1E-20 T 28-03-2018 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 Pfam PF00122 E1-E2 ATPase 96 272 8.6E-35 T 28-03-2018 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 SUPERFAMILY SSF81653 98 190 2.62E-21 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 SUPERFAMILY SSF56784 430 587 9.91E-40 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 SUPERFAMILY SSF56784 289 356 9.91E-40 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 Gene3D G3DSA:3.40.1110.10 260 433 1.4E-16 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 499 610 3.0E-23 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS08830 5faf5497cc27ae661e7628d259791fcc 778 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 69 337 3.2E-29 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 SUPERFAMILY SSF51261 483 634 6.1E-53 T 28-03-2018 IPR011055 Duplicated hybrid motif CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 SUPERFAMILY SSF55604 8 83 2.62E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 5 633 1.4E-197 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 489 613 5.5E-48 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 Pfam PF02378 Phosphotransferase system, EIIC 113 398 1.1E-32 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 Gene3D G3DSA:2.70.70.10 477 636 7.4E-57 T 28-03-2018 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 552 564 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 Pfam PF00367 phosphotransferase system, EIIB 11 43 1.1E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 Gene3D G3DSA:3.30.1360.60 6 82 2.4E-28 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWM22_RS11170 c43d9c887bfb5a8ca83aa77c71f322c5 636 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 490 610 3.5E-43 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS06730 8e2465819bd35d3413d43b0969a9767e 110 SUPERFAMILY SSF88659 2 104 4.11E-32 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS06730 8e2465819bd35d3413d43b0969a9767e 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 3 101 9.8E-42 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CWM22_RS06730 8e2465819bd35d3413d43b0969a9767e 110 Hamap MF_00245 UPF0122 protein . 3 103 21.076 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CWM22_RS06730 8e2465819bd35d3413d43b0969a9767e 110 Gene3D G3DSA:1.10.10.10 1 107 3.2E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02180 e238941df55aacd99a156b9bd0772236 301 SMART SM00530 10 64 2.1E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS02180 e238941df55aacd99a156b9bd0772236 301 Gene3D G3DSA:1.10.260.40 7 172 4.9E-13 T 28-03-2018 CWM22_RS02180 e238941df55aacd99a156b9bd0772236 301 Pfam PF01381 Helix-turn-helix 12 60 1.9E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS02180 e238941df55aacd99a156b9bd0772236 301 SUPERFAMILY SSF47413 6 65 6.97E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS10915 a0bfb7d0d171ffce270c764bfa0464ee 140 SUPERFAMILY SSF54637 7 138 4.71E-46 T 28-03-2018 IPR029069 HotDog domain CWM22_RS10915 a0bfb7d0d171ffce270c764bfa0464ee 140 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 4.2E-61 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWM22_RS10915 a0bfb7d0d171ffce270c764bfa0464ee 140 Pfam PF07977 FabA-like domain 11 130 1.3E-35 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWM22_RS10915 a0bfb7d0d171ffce270c764bfa0464ee 140 Gene3D G3DSA:3.10.129.10 1 140 5.3E-52 T 28-03-2018 CWM22_RS10915 a0bfb7d0d171ffce270c764bfa0464ee 140 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 140 33.874 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1193 18.288 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 SMART SM00663 225 504 8.2E-177 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 1131 5.8E-64 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 759 7.4E-14 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 SUPERFAMILY SSF64484 5 1183 0.0 T 28-03-2018 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 Gene3D G3DSA:2.40.40.20 336 478 3.7E-39 T 28-03-2018 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 Pfam PF00623 RNA polymerase Rpb1, domain 2 334 475 2.2E-37 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 Gene3D G3DSA:2.40.50.100 911 1031 3.8E-36 T 28-03-2018 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1183 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 Pfam PF04983 RNA polymerase Rpb1, domain 3 479 663 1.3E-33 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00875 ce6ae8feeb38dab8fa41db263be2f25d 1215 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 332 5.1E-86 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS10740 8c7c418891e7e81727130200e053d505 354 Gene3D G3DSA:3.30.70.260 270 352 1.5E-17 T 28-03-2018 CWM22_RS10740 8c7c418891e7e81727130200e053d505 354 SUPERFAMILY SSF55021 266 351 7.33E-18 T 28-03-2018 CWM22_RS10740 8c7c418891e7e81727130200e053d505 354 SMART SM00930 275 350 4.6E-22 T 28-03-2018 IPR018449 NIL domain CWM22_RS10740 8c7c418891e7e81727130200e053d505 354 Pfam PF00005 ABC transporter 26 178 4.8E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS10740 8c7c418891e7e81727130200e053d505 354 Gene3D G3DSA:3.40.50.300 2 269 3.9E-73 T 28-03-2018 CWM22_RS10740 8c7c418891e7e81727130200e053d505 354 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS10740 8c7c418891e7e81727130200e053d505 354 SUPERFAMILY SSF52540 5 249 1.86E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10740 8c7c418891e7e81727130200e053d505 354 Pfam PF09383 NIL domain 278 347 6.6E-15 T 28-03-2018 IPR018449 NIL domain CWM22_RS10740 8c7c418891e7e81727130200e053d505 354 SMART SM00382 34 230 5.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS10155 5c41b2ede64b3ccbbc5479bd828300f0 179 SUPERFAMILY SSF52218 2 176 3.55E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS10155 5c41b2ede64b3ccbbc5479bd828300f0 179 Gene3D G3DSA:3.40.50.360 1 179 1.6E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS10155 5c41b2ede64b3ccbbc5479bd828300f0 179 Pfam PF03358 NADPH-dependent FMN reductase 3 143 1.4E-25 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWM22_RS00190 2d301f39c580ec18cef5975fe6bf5a9d 278 Pfam PF04085 rod shape-determining protein MreC 121 272 4.0E-30 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CWM22_RS00190 2d301f39c580ec18cef5975fe6bf5a9d 278 PIRSF PIRSF038471 1 278 7.8E-46 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CWM22_RS00190 2d301f39c580ec18cef5975fe6bf5a9d 278 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 39 275 1.2E-33 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CWM22_RS00190 2d301f39c580ec18cef5975fe6bf5a9d 278 Gene3D G3DSA:1.20.5.1180 65 110 9.5E-4 T 28-03-2018 CWM22_RS02755 dda6e2f8f46ec4309918aac4bda8ee5b 496 SUPERFAMILY SSF52980 40 247 5.36E-46 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWM22_RS02755 dda6e2f8f46ec4309918aac4bda8ee5b 496 Pfam PF02976 DNA mismatch repair enzyme MutH 76 179 4.3E-28 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 CWM22_RS02755 dda6e2f8f46ec4309918aac4bda8ee5b 496 SMART SM00927 78 179 1.9E-18 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 CWM22_RS02755 dda6e2f8f46ec4309918aac4bda8ee5b 496 Gene3D G3DSA:3.40.600.10 1 249 2.6E-60 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 CWM22_RS02755 dda6e2f8f46ec4309918aac4bda8ee5b 496 Gene3D G3DSA:3.40.600.10 252 494 8.7E-48 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 CWM22_RS02755 dda6e2f8f46ec4309918aac4bda8ee5b 496 SUPERFAMILY SSF52980 264 492 1.18E-34 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 SUPERFAMILY SSF48592 6 133 4.75E-78 T 28-03-2018 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 SUPERFAMILY SSF48592 404 518 4.75E-78 T 28-03-2018 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 Gene3D G3DSA:1.10.560.10 1 185 1.9E-43 T 28-03-2018 IPR027413 GroEL-like equatorial domain CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 Gene3D G3DSA:3.50.7.10 186 371 9.3E-97 T 28-03-2018 IPR027409 GroEL-like apical domain CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 PRINTS PR00298 60kDa chaperonin signature 26 52 2.7E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 PRINTS PR00298 60kDa chaperonin signature 82 109 2.7E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 PRINTS PR00298 60kDa chaperonin signature 266 289 2.7E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 PRINTS PR00298 60kDa chaperonin signature 348 373 2.7E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 PRINTS PR00298 60kDa chaperonin signature 396 417 2.7E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 1.9E-252 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 40.916 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 SUPERFAMILY SSF54849 136 205 3.43E-25 T 28-03-2018 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 521 1.1E-102 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 Gene3D G3DSA:1.10.560.10 372 513 4.9E-29 T 28-03-2018 IPR027413 GroEL-like equatorial domain CWM22_RS01005 11e525dcedcab31d0a5af95c44a175a6 540 SUPERFAMILY SSF52029 182 374 1.12E-84 T 28-03-2018 IPR027409 GroEL-like apical domain CWM22_RS12255 ab9e9149dc76742b98276dca06d143cd 458 PIRSF PIRSF006060 1 458 7.0E-74 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWM22_RS12255 ab9e9149dc76742b98276dca06d143cd 458 Pfam PF00324 Amino acid permease 20 458 1.8E-107 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CWM22_RS12255 ab9e9149dc76742b98276dca06d143cd 458 ProSitePatterns PS00218 Amino acid permeases signature. 45 76 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CWM22_RS08820 41bcc6926671c9f8228f9867125b030a 540 Pfam PF00664 ABC transporter transmembrane region 22 290 1.4E-16 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS08820 41bcc6926671c9f8228f9867125b030a 540 Pfam PF00005 ABC transporter 352 496 3.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS08820 41bcc6926671c9f8228f9867125b030a 540 Gene3D G3DSA:3.40.50.300 335 540 2.2E-42 T 28-03-2018 CWM22_RS08820 41bcc6926671c9f8228f9867125b030a 540 Gene3D G3DSA:1.20.1560.10 6 326 2.9E-26 T 28-03-2018 CWM22_RS08820 41bcc6926671c9f8228f9867125b030a 540 SMART SM00382 359 535 8.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS08820 41bcc6926671c9f8228f9867125b030a 540 SUPERFAMILY SSF90123 10 315 2.09E-35 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS08820 41bcc6926671c9f8228f9867125b030a 540 SUPERFAMILY SSF52540 339 525 9.35E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12240 304e4c467d4dc0b42bd0bd682a5c4eed 176 SUPERFAMILY SSF55811 2 164 2.3E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS12240 304e4c467d4dc0b42bd0bd682a5c4eed 176 Gene3D G3DSA:3.90.79.10 1 176 3.5E-27 T 28-03-2018 CWM22_RS12240 304e4c467d4dc0b42bd0bd682a5c4eed 176 Pfam PF00293 NUDIX domain 29 146 3.0E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWM22_RS12240 304e4c467d4dc0b42bd0bd682a5c4eed 176 ProSitePatterns PS00893 Nudix box signature. 66 87 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 SUPERFAMILY SSF53244 328 478 1.57E-31 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 SUPERFAMILY SSF63418 23 107 5.1E-15 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 SUPERFAMILY SSF53623 78 340 1.7E-43 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 Gene3D G3DSA:3.40.1390.10 1 106 3.5E-15 T 28-03-2018 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 34 480 1.2E-86 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 Gene3D G3DSA:3.90.190.20 333 481 1.4E-31 T 28-03-2018 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 328 414 7.6E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 Gene3D G3DSA:3.40.1190.10 107 332 1.3E-37 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 Pfam PF08245 Mur ligase middle domain 117 308 5.3E-29 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS03840 18a2836b34ecfdcbeac061d7fad884a0 481 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 2 481 27.95 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 228 292 1.6E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 SUPERFAMILY SSF55874 281 447 5.5E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 SMART SM00387 340 451 5.8E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 SMART SM00388 227 292 3.8E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 Gene3D G3DSA:3.30.565.10 287 449 2.7E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 Gene3D G3DSA:1.10.287.130 217 286 2.0E-9 T 28-03-2018 CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 447 2.3E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 SUPERFAMILY SSF47384 210 293 3.34E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 4.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS06565 316551c7b84459078fa19cfc4c74e3ae 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 4.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS00390 5c6b3329cb8e26ab167cb8b4fdc30cca 303 Pfam PF13560 Helix-turn-helix domain 5 60 3.7E-7 T 28-03-2018 CWM22_RS00390 5c6b3329cb8e26ab167cb8b4fdc30cca 303 SUPERFAMILY SSF47413 2 68 3.1E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS00390 5c6b3329cb8e26ab167cb8b4fdc30cca 303 SMART SM00530 9 65 2.9E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS00390 5c6b3329cb8e26ab167cb8b4fdc30cca 303 Gene3D G3DSA:1.10.260.40 1 71 1.7E-13 T 28-03-2018 CWM22_RS00960 96061dc92c0e2c4a8d1157d8068079ad 353 SUPERFAMILY SSF101821 70 180 8.7E-24 T 28-03-2018 CWM22_RS00960 96061dc92c0e2c4a8d1157d8068079ad 353 TIGRFAM TIGR03107 glu_aminopep: glutamyl aminopeptidase 4 351 4.7E-200 T 28-03-2018 IPR017538 Peptidase M42, glutamyl aminopeptidase MetaCyc: PWY-5706|MetaCyc: PWY-5707|MetaCyc: PWY-7614 CWM22_RS00960 96061dc92c0e2c4a8d1157d8068079ad 353 Gene3D G3DSA:3.40.630.10 150 352 2.9E-32 T 28-03-2018 CWM22_RS00960 96061dc92c0e2c4a8d1157d8068079ad 353 Gene3D G3DSA:2.40.30.40 70 149 3.8E-19 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CWM22_RS00960 96061dc92c0e2c4a8d1157d8068079ad 353 SUPERFAMILY SSF53187 172 350 2.0E-55 T 28-03-2018 CWM22_RS00960 96061dc92c0e2c4a8d1157d8068079ad 353 SUPERFAMILY SSF53187 3 80 2.0E-55 T 28-03-2018 CWM22_RS00960 96061dc92c0e2c4a8d1157d8068079ad 353 PIRSF PIRSF001123 1 353 2.2E-128 T 28-03-2018 IPR008007 Peptidase M42 CWM22_RS00960 96061dc92c0e2c4a8d1157d8068079ad 353 Pfam PF05343 M42 glutamyl aminopeptidase 44 332 1.3E-90 T 28-03-2018 IPR008007 Peptidase M42 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 Pfam PF07724 AAA domain (Cdc48 subfamily) 323 490 1.4E-39 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 Gene3D G3DSA:1.10.8.60 498 593 7.7E-14 T 28-03-2018 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 498 566 8.1E-16 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 SUPERFAMILY SSF52540 8 263 1.12E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 SUPERFAMILY SSF52540 273 569 5.03E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 Gene3D G3DSA:1.10.8.60 192 257 3.4E-21 T 28-03-2018 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 SMART SM01086 498 588 1.7E-14 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 143 155 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 155 3.3E-5 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 Gene3D G3DSA:3.40.50.300 6 191 1.4E-16 T 28-03-2018 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 SMART SM00382 324 495 1.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 SMART SM00382 48 193 5.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 328 346 3.4E-22 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 398 416 3.4E-22 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 431 445 3.4E-22 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS09080 a96a705770a1e49f942018e614e52267 610 Gene3D G3DSA:3.40.50.300 279 497 2.9E-40 T 28-03-2018 CWM22_RS12630 11b2883bb1627f9b702a6bc3e68990c6 256 Pfam PF00005 ABC transporter 22 171 2.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS12630 11b2883bb1627f9b702a6bc3e68990c6 256 SUPERFAMILY SSF52540 4 233 4.78E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12630 11b2883bb1627f9b702a6bc3e68990c6 256 Gene3D G3DSA:3.40.50.300 1 241 5.9E-59 T 28-03-2018 CWM22_RS12630 11b2883bb1627f9b702a6bc3e68990c6 256 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS12630 11b2883bb1627f9b702a6bc3e68990c6 256 SMART SM00382 31 220 1.9E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11610 df27363c5958acbdc91a4ecaf69f1026 201 Pfam PF04854 Protein of unknown function, DUF624 15 87 1.3E-12 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CWM22_RS10515 83ca7f1874221659373f269920e49801 237 SUPERFAMILY SSF55469 1 235 1.7E-58 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWM22_RS10515 83ca7f1874221659373f269920e49801 237 PIRSF PIRSF005426 1 237 2.4E-72 T 28-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 CWM22_RS10515 83ca7f1874221659373f269920e49801 237 Gene3D G3DSA:3.40.109.10 1 237 5.1E-49 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWM22_RS10515 83ca7f1874221659373f269920e49801 237 Pfam PF00881 Nitroreductase family 11 161 3.3E-20 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWM22_RS00205 ab46b05b807af4842aa0ce496f6d7bd7 322 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 130 145 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CWM22_RS00205 ab46b05b807af4842aa0ce496f6d7bd7 322 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 317 5.4E-119 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWM22_RS00205 ab46b05b807af4842aa0ce496f6d7bd7 322 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 6 317 49.678 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWM22_RS00205 ab46b05b807af4842aa0ce496f6d7bd7 322 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 122 1.5E-50 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWM22_RS00205 ab46b05b807af4842aa0ce496f6d7bd7 322 SMART SM01400 6 122 4.8E-78 T 28-03-2018 CWM22_RS00205 ab46b05b807af4842aa0ce496f6d7bd7 322 Gene3D G3DSA:3.40.50.2020 145 318 7.8E-43 T 28-03-2018 CWM22_RS00205 ab46b05b807af4842aa0ce496f6d7bd7 322 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 2.7E-20 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWM22_RS00205 ab46b05b807af4842aa0ce496f6d7bd7 322 Gene3D G3DSA:3.40.50.2020 6 144 7.5E-62 T 28-03-2018 CWM22_RS00205 ab46b05b807af4842aa0ce496f6d7bd7 322 SUPERFAMILY SSF53271 71 308 1.74E-61 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 SMART SM00420 8 60 2.5E-21 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 Gene3D G3DSA:1.10.10.10 2 60 4.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 SUPERFAMILY SSF100950 76 229 1.02E-36 T 28-03-2018 CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 Pfam PF00455 DeoR C terminal sensor domain 77 228 2.3E-50 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 SMART SM01134 75 232 2.9E-66 T 28-03-2018 CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 7.6E-11 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 7.6E-11 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 SUPERFAMILY SSF46785 6 80 5.23E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 Pfam PF08220 DeoR-like helix-turn-helix domain 8 60 1.3E-19 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CWM22_RS07005 21fe964077a9e2b675f9316d379000b9 249 Gene3D G3DSA:3.40.50.1360 68 236 1.4E-40 T 28-03-2018 CWM22_RS00615 3a54fae0d8493c0ac9dc9dad9abe1ef2 121 Gene3D G3DSA:1.10.8.50 1 66 3.8E-23 T 28-03-2018 CWM22_RS00615 3a54fae0d8493c0ac9dc9dad9abe1ef2 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00615 3a54fae0d8493c0ac9dc9dad9abe1ef2 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.391 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00615 3a54fae0d8493c0ac9dc9dad9abe1ef2 121 Gene3D G3DSA:4.10.910.10 86 121 1.2E-26 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00615 3a54fae0d8493c0ac9dc9dad9abe1ef2 121 Pfam PF00416 Ribosomal protein S13/S18 62 108 3.1E-18 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00615 3a54fae0d8493c0ac9dc9dad9abe1ef2 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 113 1.4E-51 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00615 3a54fae0d8493c0ac9dc9dad9abe1ef2 121 Gene3D G3DSA:4.10.910.10 67 85 1.1E-18 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00615 3a54fae0d8493c0ac9dc9dad9abe1ef2 121 SUPERFAMILY SSF46946 2 112 1.77E-44 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CWM22_RS00615 3a54fae0d8493c0ac9dc9dad9abe1ef2 121 PIRSF PIRSF002134 1 121 2.6E-43 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 Pfam PF02274 Amidinotransferase 21 407 4.6E-111 T 28-03-2018 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 SUPERFAMILY SSF55909 4 410 3.93E-132 T 28-03-2018 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 PIRSF PIRSF006356 1 410 7.2E-170 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 TIGRFAM TIGR01078 arcA: arginine deiminase 7 410 1.1E-181 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 Hamap MF_00242 Arginine deiminase [arcA]. 4 410 46.474 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 PRINTS PR01466 Bacterial arginine deiminase signature 5 25 2.0E-57 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 PRINTS PR01466 Bacterial arginine deiminase signature 157 175 2.0E-57 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 PRINTS PR01466 Bacterial arginine deiminase signature 185 200 2.0E-57 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 PRINTS PR01466 Bacterial arginine deiminase signature 346 363 2.0E-57 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 PRINTS PR01466 Bacterial arginine deiminase signature 389 407 2.0E-57 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 PRINTS PR01466 Bacterial arginine deiminase signature 366 380 2.0E-57 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWM22_RS03715 2dc5f05bc9d28c4208bb2947088c9fd3 410 Gene3D G3DSA:3.75.10.10 6 408 1.3E-99 T 28-03-2018 CWM22_RS11685 a63bfaafc4583fafc2e334fe2ea04074 205 Gene3D G3DSA:1.10.3130.10 4 61 3.1E-21 T 28-03-2018 CWM22_RS11685 a63bfaafc4583fafc2e334fe2ea04074 205 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 149 9.7E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS11685 a63bfaafc4583fafc2e334fe2ea04074 205 Gene3D G3DSA:2.160.10.10 62 204 1.4E-30 T 28-03-2018 CWM22_RS11685 a63bfaafc4583fafc2e334fe2ea04074 205 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 165 1.3E-69 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CWM22_RS11685 a63bfaafc4583fafc2e334fe2ea04074 205 PIRSF PIRSF000441 2 201 4.1E-69 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CWM22_RS11685 a63bfaafc4583fafc2e334fe2ea04074 205 SUPERFAMILY SSF51161 4 174 2.08E-52 T 28-03-2018 IPR011004 Trimeric LpxA-like CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 SUPERFAMILY SSF48150 6 225 7.69E-70 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 Pfam PF00633 Helix-hairpin-helix motif 103 130 1.3E-5 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 SMART SM00478 42 193 8.1E-44 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 Gene3D G3DSA:1.10.1670.10 121 228 1.1E-27 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 10 273 2.5E-93 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 Gene3D G3DSA:1.10.340.30 24 120 2.3E-32 T 28-03-2018 CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 Pfam PF14815 NUDIX domain 239 365 5.7E-17 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 38 172 5.9E-17 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 Gene3D G3DSA:3.90.79.10 232 376 2.2E-18 T 28-03-2018 CWM22_RS05385 5e7752a492780c02e4da8e6c1db00155 376 SUPERFAMILY SSF55811 223 368 1.01E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 SUPERFAMILY SSF50800 92 194 9.77E-18 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 Pfam PF00224 Pyruvate kinase, barrel domain 3 370 1.3E-147 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 Gene3D G3DSA:3.20.20.60 3 193 1.7E-26 T 28-03-2018 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 Gene3D G3DSA:3.20.20.60 195 349 1.0E-60 T 28-03-2018 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 4 500 2.0E-152 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 Gene3D G3DSA:3.40.1380.20 350 501 1.3E-52 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 Pfam PF02887 Pyruvate kinase, alpha/beta domain 385 497 4.5E-35 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 SUPERFAMILY SSF51621 2 96 6.63E-84 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 SUPERFAMILY SSF51621 184 367 6.63E-84 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 PRINTS PR01050 Pyruvate kinase family signature 297 321 1.3E-67 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 PRINTS PR01050 Pyruvate kinase family signature 81 97 1.3E-67 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 PRINTS PR01050 Pyruvate kinase family signature 214 228 1.3E-67 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 PRINTS PR01050 Pyruvate kinase family signature 245 271 1.3E-67 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 PRINTS PR01050 Pyruvate kinase family signature 341 357 1.3E-67 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 PRINTS PR01050 Pyruvate kinase family signature 272 296 1.3E-67 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 PRINTS PR01050 Pyruvate kinase family signature 322 340 1.3E-67 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS04845 d087829c3610dc353e285cc3a926d047 501 SUPERFAMILY SSF52935 351 500 3.4E-40 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWM22_RS09645 18180b4cefa6e6b5378866670bad7a51 299 Gene3D G3DSA:3.30.2400.10 28 243 1.2E-7 T 28-03-2018 CWM22_RS09645 18180b4cefa6e6b5378866670bad7a51 299 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 3 294 3.4E-7 T 28-03-2018 IPR024455 Phage capsid CWM22_RS09645 18180b4cefa6e6b5378866670bad7a51 299 SUPERFAMILY SSF56563 6 297 5.62E-30 T 28-03-2018 CWM22_RS09645 18180b4cefa6e6b5378866670bad7a51 299 Pfam PF05065 Phage capsid family 8 295 5.4E-11 T 28-03-2018 IPR024455 Phage capsid CWM22_RS03370 34c1432fdb0be79eac84e6468b84dce1 789 SUPERFAMILY SSF46785 726 787 3.06E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03370 34c1432fdb0be79eac84e6468b84dce1 789 Pfam PF09397 Ftsk gamma domain 728 786 1.5E-26 T 28-03-2018 IPR018541 FtsK gamma domain CWM22_RS03370 34c1432fdb0be79eac84e6468b84dce1 789 SMART SM00382 463 645 8.2E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS03370 34c1432fdb0be79eac84e6468b84dce1 789 Pfam PF01580 FtsK/SpoIIIE family 437 624 9.5E-57 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CWM22_RS03370 34c1432fdb0be79eac84e6468b84dce1 789 Gene3D G3DSA:1.10.10.10 742 781 2.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03370 34c1432fdb0be79eac84e6468b84dce1 789 Gene3D G3DSA:3.40.50.300 199 741 4.2E-51 T 28-03-2018 CWM22_RS03370 34c1432fdb0be79eac84e6468b84dce1 789 SMART SM00843 725 789 5.1E-31 T 28-03-2018 IPR018541 FtsK gamma domain CWM22_RS03370 34c1432fdb0be79eac84e6468b84dce1 789 SUPERFAMILY SSF52540 402 697 3.08E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07540 0404c75c11ecebf335ef9d2b8e6d7c9d 95 SUPERFAMILY SSF141694 4 92 1.1E-26 T 28-03-2018 CWM22_RS07540 0404c75c11ecebf335ef9d2b8e6d7c9d 95 Gene3D G3DSA:2.40.30.100 5 91 5.1E-26 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CWM22_RS07540 0404c75c11ecebf335ef9d2b8e6d7c9d 95 Pfam PF08922 Domain of unknown function (DUF1905) 7 90 6.5E-24 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CWM22_RS09845 a2c8e1c10d523c421fac123f660818d9 61 SUPERFAMILY SSF47413 2 54 1.18E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS09845 a2c8e1c10d523c421fac123f660818d9 61 Pfam PF13560 Helix-turn-helix domain 2 48 2.2E-7 T 28-03-2018 CWM22_RS09845 a2c8e1c10d523c421fac123f660818d9 61 SMART SM00530 2 53 2.0E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS09845 a2c8e1c10d523c421fac123f660818d9 61 Gene3D G3DSA:1.10.3100.10 1 60 1.0E-12 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 32 9.2E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Pfam PF07501 G5 domain 606 679 3.2E-16 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Pfam PF07501 G5 domain 321 394 1.1E-17 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Pfam PF07501 G5 domain 228 299 1.6E-17 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Pfam PF07501 G5 domain 416 489 1.3E-16 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Pfam PF07501 G5 domain 513 584 5.8E-17 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Pfam PF04650 YSIRK type signal peptide 11 32 1.5E-4 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Pfam PF07580 M26 IgA1-specific Metallo-endopeptidase C-terminal region 1288 2065 1.0E-241 T 28-03-2018 IPR011505 Peptidase M26, C-terminal domain GO:0004222|GO:0005576|GO:0005618|GO:0008270 CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 SMART SM01208 317 395 4.9E-22 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 SMART SM01208 412 490 1.4E-20 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 SMART SM01208 602 680 2.5E-19 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 SMART SM01208 222 300 6.3E-22 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 SMART SM01208 507 585 4.0E-20 T 28-03-2018 IPR011098 G5 domain CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Gene3D G3DSA:2.20.230.10 603 680 8.2E-16 T 28-03-2018 CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Gene3D G3DSA:2.20.230.10 414 490 2.8E-15 T 28-03-2018 CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Gene3D G3DSA:2.20.230.10 319 395 3.9E-17 T 28-03-2018 CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Gene3D G3DSA:2.20.230.10 509 585 1.6E-16 T 28-03-2018 CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Gene3D G3DSA:2.20.230.10 221 305 4.0E-17 T 28-03-2018 CWM22_RS00280 75ee9bd52ef2822af6bceaa9208ee705 2066 Pfam PF05342 M26 IgA1-specific Metallo-endopeptidase N-terminal region 744 992 9.7E-84 T 28-03-2018 IPR008006 Peptidase M26, N-terminal domain GO:0004222|GO:0008270|GO:0016021 CWM22_RS04605 c18c6000c9bd2932ad502cfe5bdf8865 200 Pfam PF03167 Uracil DNA glycosylase superfamily 29 182 3.6E-23 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS04605 c18c6000c9bd2932ad502cfe5bdf8865 200 SUPERFAMILY SSF52141 3 187 2.62E-47 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS04605 c18c6000c9bd2932ad502cfe5bdf8865 200 SMART SM00987 27 183 1.1E-24 T 28-03-2018 CWM22_RS04605 c18c6000c9bd2932ad502cfe5bdf8865 200 SMART SM00986 27 183 1.1E-24 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS04605 c18c6000c9bd2932ad502cfe5bdf8865 200 Gene3D G3DSA:3.40.470.10 1 193 4.2E-40 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 170 198 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 8 232 9.2E-107 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 161 196 7.8E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 3 231 41.149 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 115 1.8E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 1.0E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 SUPERFAMILY SSF51161 84 218 7.72E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 Gene3D G3DSA:2.160.10.10 124 231 1.2E-33 T 28-03-2018 CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 Gene3D G3DSA:3.30.70.250 5 76 2.8E-25 T 28-03-2018 CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 6 82 7.8E-21 T 28-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CWM22_RS12450 0e959e815c69300e10314b5ee0f4767b 232 Gene3D G3DSA:2.160.10.10 77 123 1.8E-9 T 28-03-2018 CWM22_RS09530 46ccae83a173933a08e1127ef823bf0c 575 Pfam PF00664 ABC transporter transmembrane region 18 287 3.0E-29 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS09530 46ccae83a173933a08e1127ef823bf0c 575 SUPERFAMILY SSF52540 330 568 2.77E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09530 46ccae83a173933a08e1127ef823bf0c 575 Gene3D G3DSA:3.40.50.300 321 574 4.3E-73 T 28-03-2018 CWM22_RS09530 46ccae83a173933a08e1127ef823bf0c 575 SMART SM00382 358 553 2.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS09530 46ccae83a173933a08e1127ef823bf0c 575 Pfam PF00005 ABC transporter 349 496 2.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS09530 46ccae83a173933a08e1127ef823bf0c 575 SUPERFAMILY SSF90123 4 314 1.14E-56 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS09530 46ccae83a173933a08e1127ef823bf0c 575 Gene3D G3DSA:1.20.1560.10 1 320 1.9E-47 T 28-03-2018 CWM22_RS09530 46ccae83a173933a08e1127ef823bf0c 575 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 PRINTS PR01874 DNA repair protein radA signature 246 272 1.5E-86 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 PRINTS PR01874 DNA repair protein radA signature 320 343 1.5E-86 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 PRINTS PR01874 DNA repair protein radA signature 81 109 1.5E-86 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 PRINTS PR01874 DNA repair protein radA signature 122 139 1.5E-86 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 PRINTS PR01874 DNA repair protein radA signature 211 239 1.5E-86 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 PRINTS PR01874 DNA repair protein radA signature 12 36 1.5E-86 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 PRINTS PR01874 DNA repair protein radA signature 172 196 1.5E-86 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 Pfam PF13541 Subunit ChlI of Mg-chelatase 364 427 3.9E-8 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 SUPERFAMILY SSF52540 69 289 3.91E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 Pfam PF13481 AAA domain 64 220 1.3E-14 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 Hamap MF_01498 DNA repair protein RadA [radA]. 23 454 43.713 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 SMART SM00382 89 242 1.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 Gene3D G3DSA:3.40.50.300 57 259 7.0E-24 T 28-03-2018 CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 Gene3D G3DSA:3.30.230.10 260 455 4.9E-38 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 SUPERFAMILY SSF54211 301 454 2.16E-39 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 SUPERFAMILY SSF54211 253 267 2.16E-39 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS12330 26763d5f82c4a7dc847f3fdc5552281c 455 TIGRFAM TIGR00416 sms: DNA repair protein RadA 3 450 2.0E-190 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CWM22_RS01945 176309a502d95fb053f75f401b7b5167 249 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 242 3.4E-63 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS01945 176309a502d95fb053f75f401b7b5167 249 SUPERFAMILY SSF55120 1 249 1.87E-80 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS01945 176309a502d95fb053f75f401b7b5167 249 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 247 33.95 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS01945 176309a502d95fb053f75f401b7b5167 249 PIRSF PIRSF001430 1 249 2.2E-75 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS01945 176309a502d95fb053f75f401b7b5167 249 Gene3D G3DSA:3.30.70.660 107 246 1.4E-36 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS01945 176309a502d95fb053f75f401b7b5167 249 Gene3D G3DSA:3.30.70.580 1 106 6.4E-33 T 28-03-2018 CWM22_RS01945 176309a502d95fb053f75f401b7b5167 249 Pfam PF01416 tRNA pseudouridine synthase 6 104 7.6E-14 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS01945 176309a502d95fb053f75f401b7b5167 249 Pfam PF01416 tRNA pseudouridine synthase 144 248 3.7E-26 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS01250 b148e44d91bf8a31981f170811e14fb2 244 Gene3D G3DSA:3.10.180.40 65 188 6.1E-45 T 28-03-2018 CWM22_RS01250 b148e44d91bf8a31981f170811e14fb2 244 Pfam PF14506 CppA N-terminal 9 129 2.9E-43 T 28-03-2018 IPR032702 CppA, N-terminal CWM22_RS01250 b148e44d91bf8a31981f170811e14fb2 244 Pfam PF14507 CppA C-terminal 145 242 1.6E-29 T 28-03-2018 IPR032703 CppA, C-terminal CWM22_RS12815 5cb9caaeb9c2c44b959e814fbcc90ac3 372 SUPERFAMILY SSF54001 255 349 4.71E-14 T 28-03-2018 CWM22_RS12815 5cb9caaeb9c2c44b959e814fbcc90ac3 372 Pfam PF05257 CHAP domain 262 346 2.8E-13 T 28-03-2018 IPR007921 CHAP domain CWM22_RS12815 5cb9caaeb9c2c44b959e814fbcc90ac3 372 Gene3D G3DSA:1.10.530.10 86 264 3.7E-10 T 28-03-2018 CWM22_RS02775 a2f46c367a45d1698e47a430384105ed 96 Gene3D G3DSA:1.20.1640.10 1 90 6.5E-4 T 28-03-2018 CWM22_RS02775 a2f46c367a45d1698e47a430384105ed 96 Pfam PF11364 Protein of unknown function (DUF3165) 1 81 4.1E-32 T 28-03-2018 IPR021506 Protein of unknown function DUF3165 CWM22_RS12835 a634095bdd8cc111d8fdd5f623b91bd8 845 PIRSF PIRSF015040 15 845 6.7E-224 T 28-03-2018 IPR016628 ATPase, SAG2001, predicted CWM22_RS12835 a634095bdd8cc111d8fdd5f623b91bd8 845 Pfam PF12846 AAA-like domain 461 834 2.8E-97 T 28-03-2018 CWM22_RS12835 a634095bdd8cc111d8fdd5f623b91bd8 845 Gene3D G3DSA:3.40.50.300 300 806 2.4E-17 T 28-03-2018 CWM22_RS12835 a634095bdd8cc111d8fdd5f623b91bd8 845 SUPERFAMILY SSF52540 422 817 4.12E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11180 631692b101122d27d2754f3b42ad3aef 281 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 246 6.8E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWM22_RS11180 631692b101122d27d2754f3b42ad3aef 281 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 273 4.5E-56 T 28-03-2018 IPR000150 Cof family GO:0016787 CWM22_RS11180 631692b101122d27d2754f3b42ad3aef 281 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 272 1.3E-54 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS11180 631692b101122d27d2754f3b42ad3aef 281 Gene3D G3DSA:3.40.50.1000 18 280 3.7E-32 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS11180 631692b101122d27d2754f3b42ad3aef 281 Gene3D G3DSA:3.40.50.1000 1 17 0.071 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS11180 631692b101122d27d2754f3b42ad3aef 281 SUPERFAMILY SSF56784 1 277 1.29E-56 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS06015 f6d27a554788194815b7670d5a0279df 283 PIRSF PIRSF006230 1 278 5.2E-98 T 28-03-2018 IPR016478 GTPase, MTG1 CWM22_RS06015 f6d27a554788194815b7670d5a0279df 283 Gene3D G3DSA:3.40.50.300 7 97 8.2E-9 T 28-03-2018 CWM22_RS06015 f6d27a554788194815b7670d5a0279df 283 Gene3D G3DSA:3.40.50.300 98 190 2.9E-21 T 28-03-2018 CWM22_RS06015 f6d27a554788194815b7670d5a0279df 283 SUPERFAMILY SSF52540 10 193 1.86E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06015 f6d27a554788194815b7670d5a0279df 283 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 185 4.0E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS06015 f6d27a554788194815b7670d5a0279df 283 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 124 144 4.0E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS06015 f6d27a554788194815b7670d5a0279df 283 Pfam PF01926 50S ribosome-binding GTPase 124 197 1.1E-15 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS06015 f6d27a554788194815b7670d5a0279df 283 Gene3D G3DSA:1.10.1580.10 191 268 4.9E-15 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CWM22_RS06015 f6d27a554788194815b7670d5a0279df 283 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 4 274 5.3E-108 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CWM22_RS07200 aca3d9ebc8fd69a0100d7641a39ef6c3 297 Gene3D G3DSA:3.10.290.10 1 66 5.6E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS07200 aca3d9ebc8fd69a0100d7641a39ef6c3 297 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 128 142 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS07200 aca3d9ebc8fd69a0100d7641a39ef6c3 297 SUPERFAMILY SSF55120 67 294 2.26E-79 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS07200 aca3d9ebc8fd69a0100d7641a39ef6c3 297 SMART SM00363 10 73 3.6E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS07200 aca3d9ebc8fd69a0100d7641a39ef6c3 297 SUPERFAMILY SSF55174 9 95 2.65E-13 T 28-03-2018 CWM22_RS07200 aca3d9ebc8fd69a0100d7641a39ef6c3 297 Pfam PF01479 S4 domain 11 55 2.0E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS07200 aca3d9ebc8fd69a0100d7641a39ef6c3 297 Gene3D G3DSA:3.30.2350.10 73 297 2.2E-75 T 28-03-2018 CWM22_RS07200 aca3d9ebc8fd69a0100d7641a39ef6c3 297 Pfam PF00849 RNA pseudouridylate synthase 83 235 1.8E-36 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS07200 aca3d9ebc8fd69a0100d7641a39ef6c3 297 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 9 294 1.9E-96 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS12615 5eba2a2372074534782299f7d94607a5 630 Pfam PF05649 Peptidase family M13 5 383 5.3E-64 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 CWM22_RS12615 5eba2a2372074534782299f7d94607a5 630 SUPERFAMILY SSF55486 5 630 6.59E-190 T 28-03-2018 CWM22_RS12615 5eba2a2372074534782299f7d94607a5 630 Pfam PF01431 Peptidase family M13 437 627 2.8E-63 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CWM22_RS12615 5eba2a2372074534782299f7d94607a5 630 Gene3D G3DSA:3.40.390.10 303 630 9.2E-89 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CWM22_RS12615 5eba2a2372074534782299f7d94607a5 630 Gene3D G3DSA:3.40.390.10 2 267 3.4E-11 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CWM22_RS12615 5eba2a2372074534782299f7d94607a5 630 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 429 441 5.6E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CWM22_RS12615 5eba2a2372074534782299f7d94607a5 630 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 538 549 5.6E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CWM22_RS12615 5eba2a2372074534782299f7d94607a5 630 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 447 459 5.6E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CWM22_RS12615 5eba2a2372074534782299f7d94607a5 630 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 468 484 5.6E-22 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 Gene3D G3DSA:1.10.10.10 69 150 1.7E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 537 678 7.6E-31 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 SUPERFAMILY SSF52794 399 476 3.24E-7 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 Gene3D G3DSA:1.10.1790.10 290 392 2.9E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 Gene3D G3DSA:3.40.50.2300 396 484 5.9E-15 T 28-03-2018 CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 SUPERFAMILY SSF55804 533 678 4.32E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 Gene3D G3DSA:3.40.930.10 533 680 9.3E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 Gene3D G3DSA:1.10.10.10 2 62 0.069 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 583 599 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 Pfam PF00874 PRD domain 299 387 4.6E-17 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS01185 61582ce61687f19a8ad08b1a08398a1b 680 SUPERFAMILY SSF63520 276 390 1.26E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 SMART SM00382 28 237 2.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 SMART SM00382 349 514 1.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 SUPERFAMILY SSF52540 306 511 1.62E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 Gene3D G3DSA:3.40.50.300 287 512 6.5E-39 T 28-03-2018 CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 Gene3D G3DSA:3.40.50.300 1 271 8.6E-52 T 28-03-2018 CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 Pfam PF12848 ABC transporter 229 314 3.9E-21 T 28-03-2018 IPR032781 ABC-transporter extension domain CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 Pfam PF00005 ABC transporter 20 190 2.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 Pfam PF00005 ABC transporter 341 469 7.5E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS04575 e65f7a600467c14baab1660e0b2fba66 514 SUPERFAMILY SSF52540 4 241 7.96E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03600 3a4f1733f0187142ed32eb6a63efc7cd 499 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 126 218 5.4E-9 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CWM22_RS10000 d6fd1aeee81621e18cfb01a62e6197a1 250 Pfam PF00121 Triosephosphate isomerase 6 247 1.5E-92 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS10000 d6fd1aeee81621e18cfb01a62e6197a1 250 SUPERFAMILY SSF51351 3 249 4.71E-92 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS10000 d6fd1aeee81621e18cfb01a62e6197a1 250 Gene3D G3DSA:3.20.20.70 1 250 1.3E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS10000 d6fd1aeee81621e18cfb01a62e6197a1 250 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 250 38.356 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS10000 d6fd1aeee81621e18cfb01a62e6197a1 250 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 242 5.8E-60 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS10000 d6fd1aeee81621e18cfb01a62e6197a1 250 ProSitePatterns PS00171 Triosephosphate isomerase active site. 166 176 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS10630 813ce1a2dc135bf5d4c896ecf81fe5a6 360 Pfam PF11683 Protein of unknown function (DUF3278) 191 281 3.2E-11 T 28-03-2018 IPR021697 Protein of unknown function DUF3278 CWM22_RS10630 813ce1a2dc135bf5d4c896ecf81fe5a6 360 Pfam PF11683 Protein of unknown function (DUF3278) 1 125 5.4E-39 T 28-03-2018 IPR021697 Protein of unknown function DUF3278 CWM22_RS07615 447182ebe56ebbd85a42fcefdd3b8759 426 Gene3D G3DSA:3.65.10.10 219 425 1.0E-54 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS07615 447182ebe56ebbd85a42fcefdd3b8759 426 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 426 32.987 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWM22_RS07615 447182ebe56ebbd85a42fcefdd3b8759 426 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 421 2.3E-120 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS07615 447182ebe56ebbd85a42fcefdd3b8759 426 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWM22_RS07615 447182ebe56ebbd85a42fcefdd3b8759 426 Gene3D G3DSA:3.65.10.10 19 218 1.8E-50 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS07615 447182ebe56ebbd85a42fcefdd3b8759 426 ProSitePatterns PS00885 EPSP synthase signature 2. 337 355 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWM22_RS07615 447182ebe56ebbd85a42fcefdd3b8759 426 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 425 4.1E-133 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWM22_RS07615 447182ebe56ebbd85a42fcefdd3b8759 426 PIRSF PIRSF000505 1 426 4.7E-115 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWM22_RS07615 447182ebe56ebbd85a42fcefdd3b8759 426 SUPERFAMILY SSF55205 4 424 2.94E-137 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 SUPERFAMILY SSF102741 365 437 1.31E-23 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 367 436 1.8E-26 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 Pfam PF01018 GTP1/OBG 6 159 4.0E-59 T 28-03-2018 IPR006169 GTP1/OBG domain CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 Pfam PF01926 50S ribosome-binding GTPase 162 285 2.3E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 337 3.0E-139 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 Gene3D G3DSA:2.70.210.12 3 157 8.6E-57 T 28-03-2018 IPR006169 GTP1/OBG domain CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 163 183 2.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 229 247 2.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 184 202 2.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 212 227 2.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 ProSitePatterns PS00905 GTP1/OBG family signature. 214 227 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 Hamap MF_01454 GTPase Obg [obg]. 3 338 47.073 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 SUPERFAMILY SSF52540 153 341 2.6E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 162 328 2.8E-12 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 Gene3D G3DSA:3.40.50.300 160 342 3.2E-30 T 28-03-2018 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 Pfam PF09269 Domain of unknown function (DUF1967) 367 435 5.2E-26 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CWM22_RS07345 18a9560dc125004dbfa3c9615dccae18 437 SUPERFAMILY SSF82051 3 159 2.75E-55 T 28-03-2018 IPR006169 GTP1/OBG domain CWM22_RS12585 e58d9ccf223129f80d2bc1c534babff2 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 433 445 2.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS12585 e58d9ccf223129f80d2bc1c534babff2 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 373 2.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS12585 e58d9ccf223129f80d2bc1c534babff2 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 409 426 2.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS12585 e58d9ccf223129f80d2bc1c534babff2 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 388 399 2.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS12585 e58d9ccf223129f80d2bc1c534babff2 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 293 307 2.4E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS12585 e58d9ccf223129f80d2bc1c534babff2 466 SUPERFAMILY SSF51445 6 458 1.01E-154 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS12585 e58d9ccf223129f80d2bc1c534babff2 466 Pfam PF00232 Glycosyl hydrolase family 1 9 463 1.2E-124 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS12585 e58d9ccf223129f80d2bc1c534babff2 466 Gene3D G3DSA:3.20.20.80 8 464 7.6E-137 T 28-03-2018 CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.0E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 9.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 9.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 9.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 9.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 9.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 1.2E-64 T 28-03-2018 CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 SUPERFAMILY SSF51735 5 243 1.67E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 189 1.5E-7 T 28-03-2018 CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 Gene3D G3DSA:3.40.50.720 41 244 3.3E-66 T 28-03-2018 CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 Gene3D G3DSA:3.40.50.720 1 40 2.3E-8 T 28-03-2018 CWM22_RS10930 abb81d21faa3e4aba4a02a2ae059a0c3 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 241 1.8E-98 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWM22_RS07660 6dc638d6fdf6cb4f2adf4e50f228f27b 319 Pfam PF04392 ABC transporter substrate binding protein 34 310 4.5E-75 T 28-03-2018 IPR007487 ABC transporter, substrate-binding protein CWM22_RS07660 6dc638d6fdf6cb4f2adf4e50f228f27b 319 Gene3D G3DSA:3.40.50.2300 154 289 1.1E-18 T 28-03-2018 CWM22_RS07660 6dc638d6fdf6cb4f2adf4e50f228f27b 319 Gene3D G3DSA:3.40.50.2300 30 153 1.2E-16 T 28-03-2018 CWM22_RS07660 6dc638d6fdf6cb4f2adf4e50f228f27b 319 SUPERFAMILY SSF53822 39 290 2.59E-12 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS03095 bff2bcfbff7f6270ba0ac14dc9364bd3 155 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 72 106 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWM22_RS03095 bff2bcfbff7f6270ba0ac14dc9364bd3 155 PIRSF PIRSF006019 1 151 1.1E-47 T 28-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWM22_RS03095 bff2bcfbff7f6270ba0ac14dc9364bd3 155 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 117 2.4E-26 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWM22_RS03095 bff2bcfbff7f6270ba0ac14dc9364bd3 155 SUPERFAMILY SSF53927 9 141 4.35E-36 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWM22_RS03095 bff2bcfbff7f6270ba0ac14dc9364bd3 155 Gene3D G3DSA:3.40.140.10 5 150 1.5E-37 T 28-03-2018 CWM22_RS09890 b8271aee102ab6831ec3bd2c609638d8 312 Pfam PF02687 FtsX-like permease family 216 311 1.1E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWM22_RS09890 b8271aee102ab6831ec3bd2c609638d8 312 PIRSF PIRSF003097 2 312 3.4E-77 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CWM22_RS04715 c8d5ca943ef1716d7c9fe004d72057f2 378 Pfam PF04055 Radical SAM superfamily 10 172 1.9E-23 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWM22_RS04715 c8d5ca943ef1716d7c9fe004d72057f2 378 Gene3D G3DSA:3.20.20.70 3 320 8.3E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS04715 c8d5ca943ef1716d7c9fe004d72057f2 378 Pfam PF06969 HemN C-terminal domain 300 365 7.3E-20 T 28-03-2018 IPR010723 HemN, C-terminal CWM22_RS04715 c8d5ca943ef1716d7c9fe004d72057f2 378 SUPERFAMILY SSF102114 4 375 2.49E-118 T 28-03-2018 CWM22_RS04715 c8d5ca943ef1716d7c9fe004d72057f2 378 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 366 1.4E-115 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CWM22_RS04715 c8d5ca943ef1716d7c9fe004d72057f2 378 SMART SM00729 5 221 1.1E-56 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 Pfam PF00575 S1 RNA binding domain 190 262 5.9E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 Pfam PF00575 S1 RNA binding domain 106 173 2.3E-12 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 Pfam PF00575 S1 RNA binding domain 275 348 4.6E-24 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 Pfam PF00575 S1 RNA binding domain 15 74 1.2E-7 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 PRINTS PR00681 Ribosomal protein S1 signature 331 349 2.3E-37 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 PRINTS PR00681 Ribosomal protein S1 signature 128 145 2.3E-37 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 PRINTS PR00681 Ribosomal protein S1 signature 17 35 2.3E-37 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 PRINTS PR00681 Ribosomal protein S1 signature 110 126 2.3E-37 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 PRINTS PR00681 Ribosomal protein S1 signature 292 311 2.3E-37 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 PRINTS PR00681 Ribosomal protein S1 signature 214 235 2.3E-37 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 PRINTS PR00681 Ribosomal protein S1 signature 157 177 2.3E-37 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 Gene3D G3DSA:2.40.50.140 187 267 1.2E-23 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 SUPERFAMILY SSF50249 106 186 2.69E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 SUPERFAMILY SSF50249 278 361 4.7E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 Gene3D G3DSA:2.40.50.140 2 96 1.4E-8 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 SMART SM00316 105 173 2.1E-10 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 SMART SM00316 277 348 2.4E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 SMART SM00316 192 262 1.7E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 SMART SM00316 15 91 3.5E-5 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 Gene3D G3DSA:2.40.50.140 107 180 1.1E-12 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 SUPERFAMILY SSF50249 192 279 4.4E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 Gene3D G3DSA:2.40.50.140 279 381 4.0E-29 T 28-03-2018 CWM22_RS07265 474156e32dfb20a85f03810253e83ad8 401 SUPERFAMILY SSF50249 4 103 4.93E-12 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS02510 e35dfaed6f1b6e52a6a3df80c44dc533 338 PIRSF PIRSF037431 1 332 2.6E-116 T 28-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 CWM22_RS02510 e35dfaed6f1b6e52a6a3df80c44dc533 338 SMART SM00387 233 326 0.0012 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02510 e35dfaed6f1b6e52a6a3df80c44dc533 338 Pfam PF07730 Histidine kinase 129 197 5.0E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CWM22_RS02510 e35dfaed6f1b6e52a6a3df80c44dc533 338 SUPERFAMILY SSF55874 191 324 1.64E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02510 e35dfaed6f1b6e52a6a3df80c44dc533 338 Gene3D G3DSA:3.30.565.10 194 332 3.0E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 Gene3D G3DSA:2.30.30.90 123 214 1.1E-11 T 28-03-2018 CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 68 130 1.7E-24 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 SUPERFAMILY SSF46785 1 60 7.76E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 SMART SM00899 142 214 4.3E-4 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 Gene3D G3DSA:1.10.10.10 2 71 1.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 53 7.2E-11 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 SUPERFAMILY SSF47979 67 134 3.27E-22 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 SMART SM00529 23 122 5.2E-26 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 Gene3D G3DSA:1.10.60.10 72 122 5.3E-23 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CWM22_RS12650 316686798e053e4de4b7fe3d60d59fe6 219 Pfam PF04023 FeoA domain 142 213 1.2E-8 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWM22_RS03845 6d68c2a5d1e0de59d25f534e1c6de6b5 248 Pfam PF01553 Acyltransferase 22 143 9.1E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CWM22_RS03845 6d68c2a5d1e0de59d25f534e1c6de6b5 248 SUPERFAMILY SSF69593 2 215 2.62E-56 T 28-03-2018 CWM22_RS03845 6d68c2a5d1e0de59d25f534e1c6de6b5 248 Gene3D G3DSA:3.40.1130.10 1 208 6.2E-33 T 28-03-2018 CWM22_RS03845 6d68c2a5d1e0de59d25f534e1c6de6b5 248 SMART SM00563 36 146 2.0E-23 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 TIGRFAM TIGR01363 strep_his_triad: streptococcal histidine triad protein 3 248 4.7E-106 T 28-03-2018 IPR023832 Histidine triad protein CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 TIGRFAM TIGR01363 strep_his_triad: streptococcal histidine triad protein 244 320 1.2E-28 T 28-03-2018 IPR023832 Histidine triad protein CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 TIGRFAM TIGR01363 strep_his_triad: streptococcal histidine triad protein 757 863 4.6E-11 T 28-03-2018 IPR023832 Histidine triad protein CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 SUPERFAMILY SSF142887 573 612 9.42E-5 T 28-03-2018 CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 Pfam PF04270 Streptococcal histidine triad protein 896 911 0.083 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 Pfam PF04270 Streptococcal histidine triad protein 402 451 4.8E-17 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 Pfam PF04270 Streptococcal histidine triad protein 770 827 4.4E-15 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 Pfam PF04270 Streptococcal histidine triad protein 179 228 1.7E-25 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 Pfam PF04270 Streptococcal histidine triad protein 279 318 1.1E-14 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 Pfam PF04270 Streptococcal histidine triad protein 71 89 0.0024 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 Pfam PF04270 Streptococcal histidine triad protein 673 728 4.0E-15 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 Pfam PF04270 Streptococcal histidine triad protein 578 606 8.4E-4 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 SUPERFAMILY SSF142887 274 322 1.57E-15 T 28-03-2018 CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 SUPERFAMILY SSF142887 398 450 2.88E-15 T 28-03-2018 CWM22_RS02040 70c566b8ec3c2f8b0e165e7c2ebccc00 1051 SUPERFAMILY SSF142887 175 227 4.32E-20 T 28-03-2018 CWM22_RS10595 afffa0980e91384b9141ed557931ccd8 332 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 5.3E-5 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWM22_RS10595 afffa0980e91384b9141ed557931ccd8 332 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 330 4.4E-79 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWM22_RS10595 afffa0980e91384b9141ed557931ccd8 332 ProSitePatterns PS01348 MraY family signature 2. 164 175 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWM22_RS10595 afffa0980e91384b9141ed557931ccd8 332 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 331 22.017 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWM22_RS10595 afffa0980e91384b9141ed557931ccd8 332 Pfam PF00953 Glycosyl transferase family 4 80 244 6.5E-39 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWM22_RS09995 a5837bde65246ac6e699007e2bd6f298 269 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 28-03-2018 CWM22_RS09995 a5837bde65246ac6e699007e2bd6f298 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 263 4.5E-72 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09995 a5837bde65246ac6e699007e2bd6f298 269 Gene3D G3DSA:3.40.50.1000 1 269 6.2E-48 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09995 a5837bde65246ac6e699007e2bd6f298 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 1.0E-67 T 28-03-2018 IPR000150 Cof family GO:0016787 CWM22_RS09995 a5837bde65246ac6e699007e2bd6f298 269 SUPERFAMILY SSF56784 1 268 2.49E-80 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09995 a5837bde65246ac6e699007e2bd6f298 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 236 4.6E-33 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWM22_RS09995 a5837bde65246ac6e699007e2bd6f298 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 CWM22_RS07210 1ae801f9e065d3178dce874a601f34c5 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.5E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS07210 1ae801f9e065d3178dce874a601f34c5 304 SUPERFAMILY SSF46785 1 83 1.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07210 1ae801f9e065d3178dce874a601f34c5 304 Gene3D G3DSA:1.10.10.10 1 81 1.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07210 1ae801f9e065d3178dce874a601f34c5 304 Gene3D G3DSA:3.40.190.10 83 205 9.6E-12 T 28-03-2018 CWM22_RS07210 1ae801f9e065d3178dce874a601f34c5 304 Pfam PF03466 LysR substrate binding domain 97 295 1.6E-14 T 28-03-2018 IPR005119 LysR, substrate-binding CWM22_RS07210 1ae801f9e065d3178dce874a601f34c5 304 SUPERFAMILY SSF53850 96 298 5.79E-15 T 28-03-2018 CWM22_RS07210 1ae801f9e065d3178dce874a601f34c5 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS07210 1ae801f9e065d3178dce874a601f34c5 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS07210 1ae801f9e065d3178dce874a601f34c5 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWM22_RS04660 516631777ad8506e6ba87c5ec509c823 224 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 5 217 1.6E-80 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWM22_RS04660 516631777ad8506e6ba87c5ec509c823 224 SUPERFAMILY SSF100950 2 143 5.58E-43 T 28-03-2018 CWM22_RS04660 516631777ad8506e6ba87c5ec509c823 224 SUPERFAMILY SSF75445 127 204 6.54E-20 T 28-03-2018 CWM22_RS04660 516631777ad8506e6ba87c5ec509c823 224 Gene3D G3DSA:3.40.50.1360 1 138 1.4E-39 T 28-03-2018 CWM22_RS04660 516631777ad8506e6ba87c5ec509c823 224 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 50 217 9.6E-58 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWM22_RS04660 516631777ad8506e6ba87c5ec509c823 224 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 221 32.23 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWM22_RS04660 516631777ad8506e6ba87c5ec509c823 224 Gene3D G3DSA:3.30.70.260 139 201 8.6E-21 T 28-03-2018 CWM22_RS10335 f30bcb9278097bcf5212c9ea02ece037 144 SUPERFAMILY SSF52788 1 138 9.29E-43 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWM22_RS10335 f30bcb9278097bcf5212c9ea02ece037 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 6.4E-15 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWM22_RS10335 f30bcb9278097bcf5212c9ea02ece037 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 76 91 6.4E-15 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWM22_RS10335 f30bcb9278097bcf5212c9ea02ece037 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 41 57 6.4E-15 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWM22_RS10335 f30bcb9278097bcf5212c9ea02ece037 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 111 126 6.4E-15 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWM22_RS10335 f30bcb9278097bcf5212c9ea02ece037 144 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 135 1.0E-31 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWM22_RS10335 f30bcb9278097bcf5212c9ea02ece037 144 SMART SM00226 2 137 4.6E-33 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWM22_RS10335 f30bcb9278097bcf5212c9ea02ece037 144 Gene3D G3DSA:3.40.50.2300 1 144 8.5E-42 T 28-03-2018 CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 PRINTS PR00131 Glycosyl hydrolase family 1 signature 455 467 1.3E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 PRINTS PR00131 Glycosyl hydrolase family 1 signature 430 447 1.3E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 PRINTS PR00131 Glycosyl hydrolase family 1 signature 409 420 1.3E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 PRINTS PR00131 Glycosyl hydrolase family 1 signature 323 337 1.3E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 PRINTS PR00131 Glycosyl hydrolase family 1 signature 388 396 1.3E-13 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 Gene3D G3DSA:3.20.20.80 1 494 2.6E-145 T 28-03-2018 CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 SUPERFAMILY SSF51445 81 491 5.52E-152 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 SUPERFAMILY SSF51445 2 40 5.52E-152 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 Pfam PF00232 Glycosyl hydrolase family 1 3 35 7.4E-9 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11155 a6da6ea918d65dccb1a4acf0bf4d5b2f 494 Pfam PF00232 Glycosyl hydrolase family 1 86 490 3.6E-113 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS03645 d02ad2a4a6f0695f0d00b0a2b113dae3 181 Pfam PF03358 NADPH-dependent FMN reductase 3 124 7.2E-25 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWM22_RS03645 d02ad2a4a6f0695f0d00b0a2b113dae3 181 SUPERFAMILY SSF52218 1 180 3.46E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS03645 d02ad2a4a6f0695f0d00b0a2b113dae3 181 Gene3D G3DSA:3.40.50.360 1 181 1.6E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS03010 142ec54dcf29e0d06a7ca66ff07faa24 384 SUPERFAMILY SSF53901 168 383 1.99E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS03010 142ec54dcf29e0d06a7ca66ff07faa24 384 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 382 5.3E-158 T 28-03-2018 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922 CWM22_RS03010 142ec54dcf29e0d06a7ca66ff07faa24 384 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2 164 8.8E-18 T 28-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 CWM22_RS03010 142ec54dcf29e0d06a7ca66ff07faa24 384 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 178 246 5.0E-10 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CWM22_RS03010 142ec54dcf29e0d06a7ca66ff07faa24 384 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 257 346 4.7E-12 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CWM22_RS03010 142ec54dcf29e0d06a7ca66ff07faa24 384 Gene3D G3DSA:3.40.47.10 175 318 6.1E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS03010 142ec54dcf29e0d06a7ca66ff07faa24 384 SUPERFAMILY SSF53901 2 166 5.76E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS03010 142ec54dcf29e0d06a7ca66ff07faa24 384 Gene3D G3DSA:3.40.47.10 7 170 2.6E-10 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 PRINTS PR00132 Glycosyl hydrolase family 2 signature 282 296 2.1E-17 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 PRINTS PR00132 Glycosyl hydrolase family 2 signature 313 331 2.1E-17 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 PRINTS PR00132 Glycosyl hydrolase family 2 signature 498 513 2.1E-17 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 PRINTS PR00132 Glycosyl hydrolase family 2 signature 397 412 2.1E-17 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 Gene3D G3DSA:3.20.20.80 273 592 3.0E-56 T 28-03-2018 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 SUPERFAMILY SSF49785 1 178 2.83E-41 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 SUPERFAMILY SSF51445 273 591 2.14E-78 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 273 591 6.6E-73 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 323 348 - T 28-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 Gene3D G3DSA:2.60.40.10 178 272 3.0E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 Pfam PF00703 Glycosyl hydrolases family 2 180 271 3.7E-9 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 397 411 - T 28-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 14 177 9.6E-14 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 Gene3D G3DSA:2.60.120.260 1 177 3.2E-31 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS08120 9d663a2562ffeccc8f261b9124a3f624 599 SUPERFAMILY SSF49303 180 271 2.82E-15 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CWM22_RS00860 d4bed222c809c0ca838fae0127cd8d88 807 SUPERFAMILY SSF53955 78 301 1.52E-56 T 28-03-2018 IPR023346 Lysozyme-like domain CWM22_RS00860 d4bed222c809c0ca838fae0127cd8d88 807 SUPERFAMILY SSF56601 335 758 4.02E-90 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS00860 d4bed222c809c0ca838fae0127cd8d88 807 SUPERFAMILY SSF56601 269 281 4.02E-90 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS00860 d4bed222c809c0ca838fae0127cd8d88 807 Gene3D G3DSA:3.40.710.10 306 806 3.8E-69 T 28-03-2018 CWM22_RS00860 d4bed222c809c0ca838fae0127cd8d88 807 Pfam PF00912 Transglycosylase 90 263 2.7E-50 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWM22_RS00860 d4bed222c809c0ca838fae0127cd8d88 807 Gene3D G3DSA:1.10.3810.10 81 294 1.8E-56 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWM22_RS00860 d4bed222c809c0ca838fae0127cd8d88 807 Pfam PF00905 Penicillin binding protein transpeptidase domain 400 633 5.0E-25 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 SUPERFAMILY SSF55068 1 157 4.84E-56 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 157 33.214 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 169 296 35.906 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 Pfam PF01625 Peptide methionine sulfoxide reductase 3 152 1.3E-53 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 SUPERFAMILY SSF51316 170 309 3.3E-57 T 28-03-2018 IPR011057 Mss4-like CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 Gene3D G3DSA:3.30.1060.10 1 164 4.8E-56 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 151 5.8E-45 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 Gene3D G3DSA:2.170.150.20 165 312 1.0E-50 T 28-03-2018 CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 171 304 2.4E-62 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CWM22_RS01470 e4cca04ed4467e9aefeae71ed7da29f6 312 Pfam PF01641 SelR domain 177 295 1.3E-45 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CWM22_RS13095 62461d27078fd8368d1b569758e5cc93 213 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS13095 62461d27078fd8368d1b569758e5cc93 213 Gene3D G3DSA:3.40.50.300 1 212 2.7E-63 T 28-03-2018 CWM22_RS13095 62461d27078fd8368d1b569758e5cc93 213 TIGRFAM TIGR03608 L_ocin_972_ABC: putative bacteriocin export ABC transporter, lactococcin 972 group 4 207 2.2E-80 T 28-03-2018 IPR019895 Putative bacteriocin export ABC transporter, lactococcin 972 group CWM22_RS13095 62461d27078fd8368d1b569758e5cc93 213 SMART SM00382 26 211 3.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS13095 62461d27078fd8368d1b569758e5cc93 213 SUPERFAMILY SSF52540 1 208 5.54E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13095 62461d27078fd8368d1b569758e5cc93 213 Pfam PF00005 ABC transporter 18 164 6.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS04890 d5510e1801ee62ab8dc403dadf19df37 210 SUPERFAMILY SSF52540 1 207 2.61E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04890 d5510e1801ee62ab8dc403dadf19df37 210 Pfam PF00005 ABC transporter 18 162 1.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS04890 d5510e1801ee62ab8dc403dadf19df37 210 Gene3D G3DSA:3.40.50.300 1 209 1.1E-61 T 28-03-2018 CWM22_RS04890 d5510e1801ee62ab8dc403dadf19df37 210 SMART SM00382 26 210 3.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS04890 d5510e1801ee62ab8dc403dadf19df37 210 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 SMART SM00480 18 373 1.3E-142 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 Gene3D G3DSA:3.10.150.10 131 255 1.1E-30 T 28-03-2018 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 SUPERFAMILY SSF55979 253 377 1.71E-29 T 28-03-2018 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 Gene3D G3DSA:3.10.150.10 257 378 6.2E-23 T 28-03-2018 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 SUPERFAMILY SSF55979 135 251 2.41E-25 T 28-03-2018 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 3 126 1.7E-23 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 PIRSF PIRSF000804 2 378 6.5E-96 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 Gene3D G3DSA:3.10.150.10 1 130 1.7E-20 T 28-03-2018 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 2.5E-28 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 251 2.5E-30 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 3 377 1.2E-90 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS00010 eebb22d26a780e8dc1778b356ddfea53 378 SUPERFAMILY SSF55979 3 129 2.07E-17 T 28-03-2018 CWM22_RS04645 27ee088103458a8c3ad0edc805edfb16 184 Gene3D G3DSA:3.90.220.20 1 169 8.5E-19 T 28-03-2018 CWM22_RS04645 27ee088103458a8c3ad0edc805edfb16 184 Pfam PF01420 Type I restriction modification DNA specificity domain 57 167 2.2E-7 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CWM22_RS04645 27ee088103458a8c3ad0edc805edfb16 184 SUPERFAMILY SSF116734 6 183 7.19E-23 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 SMART SM00831 9 82 2.5E-26 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 SUPERFAMILY SSF81665 234 328 1.01E-126 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 SUPERFAMILY SSF81665 10 123 1.01E-126 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 SUPERFAMILY SSF81665 672 886 1.01E-126 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 Pfam PF00122 E1-E2 ATPase 120 314 1.9E-52 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 Gene3D G3DSA:1.20.1110.10 528 891 8.8E-97 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 517 528 7.4E-38 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 7.4E-38 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 549 7.4E-38 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 7.4E-38 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 641 7.4E-38 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 646 658 7.4E-38 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 636 1.3E-23 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 SUPERFAMILY SSF81660 341 521 5.89E-48 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 476 494 2.1E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 622 638 2.1E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 654 679 2.1E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 594 610 2.1E-16 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 Pfam PF00689 Cation transporting ATPase, C-terminus 707 883 1.7E-45 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 225 381 1.9E-25 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 184 4.5E-20 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 588 703 3.0E-34 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 Gene3D G3DSA:2.70.150.10 19 234 7.2E-48 T 28-03-2018 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 SUPERFAMILY SSF81653 123 233 1.96E-30 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 Pfam PF00690 Cation transporter/ATPase, N-terminus 11 76 7.9E-20 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 SUPERFAMILY SSF56784 473 726 2.84E-58 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 SUPERFAMILY SSF56784 332 352 2.84E-58 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 336 342 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWM22_RS09975 2c92af99a4e13c640e6af69ef3cc86f7 894 Gene3D G3DSA:3.40.1110.10 296 524 8.7E-49 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWM22_RS11560 2bfb1b92bfcfa6deeaf86a2074d1e3e7 242 Pfam PF00588 SpoU rRNA Methylase family 96 235 1.6E-40 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CWM22_RS11560 2bfb1b92bfcfa6deeaf86a2074d1e3e7 242 Gene3D G3DSA:3.30.1330.30 1 75 3.5E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWM22_RS11560 2bfb1b92bfcfa6deeaf86a2074d1e3e7 242 Gene3D G3DSA:3.40.1280.10 76 242 2.8E-45 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWM22_RS11560 2bfb1b92bfcfa6deeaf86a2074d1e3e7 242 SUPERFAMILY SSF75217 85 240 5.3E-47 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWM22_RS11560 2bfb1b92bfcfa6deeaf86a2074d1e3e7 242 SMART SM00967 6 80 1.2E-15 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWM22_RS11560 2bfb1b92bfcfa6deeaf86a2074d1e3e7 242 SUPERFAMILY SSF55315 2 76 2.36E-18 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWM22_RS11560 2bfb1b92bfcfa6deeaf86a2074d1e3e7 242 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 79 1.8E-15 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWM22_RS11560 2bfb1b92bfcfa6deeaf86a2074d1e3e7 242 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 241 2.0E-79 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CWM22_RS01625 23957fc2facb9e4c09357aa29c93f555 171 PIRSF PIRSF005384 1 148 7.6E-48 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS01625 23957fc2facb9e4c09357aa29c93f555 171 Gene3D G3DSA:3.40.1400.10 1 169 1.8E-54 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS01625 23957fc2facb9e4c09357aa29c93f555 171 SUPERFAMILY SSF89623 1 151 1.44E-48 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS01625 23957fc2facb9e4c09357aa29c93f555 171 TIGRFAM TIGR01119 lacB: galactose-6-phosphate isomerase, LacB subunit 1 171 3.3E-100 T 28-03-2018 IPR004784 Galactose-6-phosphate isomerase subunit LacB GO:0005990|GO:0016861|GO:0050044 KEGG: 00052+5.3.1.26 CWM22_RS01625 23957fc2facb9e4c09357aa29c93f555 171 Pfam PF02502 Ribose/Galactose Isomerase 3 141 1.6E-40 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS01625 23957fc2facb9e4c09357aa29c93f555 171 Hamap MF_01556 Galactose-6-phosphate isomerase subunit LacB [lacB]. 1 171 45.865 T 28-03-2018 IPR004784 Galactose-6-phosphate isomerase subunit LacB GO:0005990|GO:0016861|GO:0050044 KEGG: 00052+5.3.1.26 CWM22_RS01625 23957fc2facb9e4c09357aa29c93f555 171 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 2.4E-34 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWM22_RS05900 df1bf038530e2e4515e5ea78b38bc07c 73 SUPERFAMILY SSF47413 3 66 8.58E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS05900 df1bf038530e2e4515e5ea78b38bc07c 73 SMART SM00530 4 59 1.4E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS05900 df1bf038530e2e4515e5ea78b38bc07c 73 Pfam PF01381 Helix-turn-helix 5 59 3.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS05900 df1bf038530e2e4515e5ea78b38bc07c 73 Gene3D G3DSA:1.10.3100.10 3 73 3.6E-21 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS06435 db0e5540b01441e3e91fdb5a001deba1 169 SUPERFAMILY SSF88659 84 169 8.41E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS06435 db0e5540b01441e3e91fdb5a001deba1 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 166 4.0E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS06435 db0e5540b01441e3e91fdb5a001deba1 169 Pfam PF04545 Sigma-70, region 4 116 165 1.2E-9 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS06435 db0e5540b01441e3e91fdb5a001deba1 169 Gene3D G3DSA:1.10.10.10 58 169 4.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05715 db0e5540b01441e3e91fdb5a001deba1 169 SUPERFAMILY SSF88659 84 169 8.41E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS05715 db0e5540b01441e3e91fdb5a001deba1 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 166 4.0E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS05715 db0e5540b01441e3e91fdb5a001deba1 169 Pfam PF04545 Sigma-70, region 4 116 165 1.2E-9 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS05715 db0e5540b01441e3e91fdb5a001deba1 169 Gene3D G3DSA:1.10.10.10 58 169 4.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 1.1E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 177 197 1.1E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 Gene3D G3DSA:1.20.120.430 71 241 1.3E-42 T 28-03-2018 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 SUPERFAMILY SSF52540 4 168 8.89E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 1.0E-32 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 SUPERFAMILY SSF52540 138 435 3.38E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.127 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 Gene3D G3DSA:3.30.300.20 358 434 2.7E-35 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 Gene3D G3DSA:1.20.120.430 2 70 1.1E-18 T 28-03-2018 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 Gene3D G3DSA:1.20.120.430 242 357 3.2E-16 T 28-03-2018 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 PIRSF PIRSF006485 2 436 4.9E-171 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 5.0E-174 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 8.8E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 1.3E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 125 8.7E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS10510 6fdd5559efec47d59109f1d3095409db 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 175 344 5.2E-26 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS01840 1f84e19c077bb2baa1f8502f2c5c6186 582 SMART SM00382 366 551 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS01840 1f84e19c077bb2baa1f8502f2c5c6186 582 SUPERFAMILY SSF90123 13 322 1.44E-68 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS01840 1f84e19c077bb2baa1f8502f2c5c6186 582 Pfam PF00664 ABC transporter transmembrane region 27 295 5.2E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS01840 1f84e19c077bb2baa1f8502f2c5c6186 582 Gene3D G3DSA:1.20.1560.10 3 327 2.4E-67 T 28-03-2018 CWM22_RS01840 1f84e19c077bb2baa1f8502f2c5c6186 582 Pfam PF00005 ABC transporter 357 505 3.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS01840 1f84e19c077bb2baa1f8502f2c5c6186 582 Gene3D G3DSA:3.40.50.300 328 580 4.7E-74 T 28-03-2018 CWM22_RS01840 1f84e19c077bb2baa1f8502f2c5c6186 582 SUPERFAMILY SSF52540 338 575 4.15E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01835 b31c3e043291518937da6be21c9c861a 365 Pfam PF01070 FMN-dependent dehydrogenase 169 336 4.8E-17 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CWM22_RS01835 b31c3e043291518937da6be21c9c861a 365 PIRSF PIRSF003314 8 351 2.5E-113 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CWM22_RS01835 b31c3e043291518937da6be21c9c861a 365 SUPERFAMILY SSF51395 30 357 1.83E-77 T 28-03-2018 CWM22_RS01835 b31c3e043291518937da6be21c9c861a 365 Gene3D G3DSA:3.20.20.70 8 353 9.9E-65 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS01835 b31c3e043291518937da6be21c9c861a 365 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 8 341 35.298 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CWM22_RS01835 b31c3e043291518937da6be21c9c861a 365 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 11 339 1.8E-110 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CWM22_RS11900 08636e3e2a1bca158f44bfcb10daa583 288 SUPERFAMILY SSF118352 231 287 3.66E-20 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CWM22_RS11900 08636e3e2a1bca158f44bfcb10daa583 288 Gene3D G3DSA:3.90.1280.10 233 286 3.3E-23 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CWM22_RS11900 08636e3e2a1bca158f44bfcb10daa583 288 PIRSF PIRSF005261 1 288 8.2E-71 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CWM22_RS11900 08636e3e2a1bca158f44bfcb10daa583 288 SUPERFAMILY SSF64397 1 239 7.32E-63 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CWM22_RS11900 08636e3e2a1bca158f44bfcb10daa583 288 Pfam PF01430 Hsp33 protein 2 278 2.6E-78 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CWM22_RS11900 08636e3e2a1bca158f44bfcb10daa583 288 Gene3D G3DSA:3.55.30.10 1 232 8.5E-61 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CWM22_RS11900 08636e3e2a1bca158f44bfcb10daa583 288 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 288 34.065 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CWM22_RS09770 8090dcfcf8f509539ddc7e0eff5312fb 87 Gene3D G3DSA:1.10.260.40 1 69 2.3E-7 T 28-03-2018 CWM22_RS09770 8090dcfcf8f509539ddc7e0eff5312fb 87 SUPERFAMILY SSF47413 3 52 5.94E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS01980 d289912b35aba56fe3f4f997f591b55b 333 SMART SM00829 13 330 4.3E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWM22_RS01980 d289912b35aba56fe3f4f997f591b55b 333 Gene3D G3DSA:3.90.180.10 1 333 2.3E-67 T 28-03-2018 CWM22_RS01980 d289912b35aba56fe3f4f997f591b55b 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 89 7.6E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWM22_RS01980 d289912b35aba56fe3f4f997f591b55b 333 SUPERFAMILY SSF51735 118 263 6.74E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS01980 d289912b35aba56fe3f4f997f591b55b 333 Pfam PF13602 Zinc-binding dehydrogenase 187 330 7.1E-28 T 28-03-2018 CWM22_RS01980 d289912b35aba56fe3f4f997f591b55b 333 SUPERFAMILY SSF50129 1 152 3.96E-35 T 28-03-2018 IPR011032 GroES-like CWM22_RS00915 bcd690384620b8c8025304188a96e713 144 Pfam PF15980 Putative Competence protein ComGF 37 134 3.1E-22 T 28-03-2018 IPR016977 Competence operon G, ComGF CWM22_RS00915 bcd690384620b8c8025304188a96e713 144 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 22 9.6E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWM22_RS00915 bcd690384620b8c8025304188a96e713 144 PIRSF PIRSF031611 1 144 2.5E-54 T 28-03-2018 IPR016977 Competence operon G, ComGF CWM22_RS09705 747211329d0ebd277fe3c5ac95f6e4ee 114 SUPERFAMILY SSF46785 9 100 3.54E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS09705 747211329d0ebd277fe3c5ac95f6e4ee 114 Gene3D G3DSA:1.10.10.10 5 100 8.4E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS09705 747211329d0ebd277fe3c5ac95f6e4ee 114 Pfam PF09639 YjcQ protein 11 108 1.9E-20 T 28-03-2018 IPR018597 Bacteriophage Tuc2009, YjcQ CWM22_RS07115 fcba35a475327b028b34cdf62bb3dc2d 302 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 302 93.513 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS07115 fcba35a475327b028b34cdf62bb3dc2d 302 Gene3D G3DSA:3.30.43.10 11 85 3.3E-19 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CWM22_RS07115 fcba35a475327b028b34cdf62bb3dc2d 302 Gene3D G3DSA:3.90.78.10 199 295 1.3E-28 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS07115 fcba35a475327b028b34cdf62bb3dc2d 302 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 197 295 8.3E-28 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS07115 fcba35a475327b028b34cdf62bb3dc2d 302 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 20 296 1.0E-71 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS07115 fcba35a475327b028b34cdf62bb3dc2d 302 SUPERFAMILY SSF56176 10 191 4.05E-45 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWM22_RS07115 fcba35a475327b028b34cdf62bb3dc2d 302 SUPERFAMILY SSF56194 192 297 1.31E-37 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS07115 fcba35a475327b028b34cdf62bb3dc2d 302 Gene3D G3DSA:3.30.465.10 86 198 1.4E-35 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWM22_RS07115 fcba35a475327b028b34cdf62bb3dc2d 302 Pfam PF01565 FAD binding domain 33 161 5.1E-24 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CWM22_RS04465 f1bf99b88fdffd49fe96ecef63a2fa79 560 Gene3D G3DSA:3.40.50.1820 245 528 1.4E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS04465 f1bf99b88fdffd49fe96ecef63a2fa79 560 Pfam PF16929 Accessory Sec system GspB-transporter 6 558 2.0E-170 T 28-03-2018 IPR022267 Accessory Sec system protein Asp2 GO:0015031 CWM22_RS04465 f1bf99b88fdffd49fe96ecef63a2fa79 560 TIGRFAM TIGR03712 acc_sec_asp2: accessory Sec system protein Asp2 86 558 1.9E-166 T 28-03-2018 IPR022267 Accessory Sec system protein Asp2 GO:0015031 CWM22_RS04465 f1bf99b88fdffd49fe96ecef63a2fa79 560 SUPERFAMILY SSF53474 336 452 5.6E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS03525 ef1ef71eae2c9cf2ec787410f6b6c208 244 Pfam PF03883 Peroxide stress protein YaaA 1 228 1.8E-53 T 28-03-2018 IPR005583 Peroxide stress protein YaaA CWM22_RS03525 ef1ef71eae2c9cf2ec787410f6b6c208 244 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 241 26.552 T 28-03-2018 IPR005583 Peroxide stress protein YaaA CWM22_RS05200 35f723239c5d778e8ae03e1c102c157a 377 SUPERFAMILY SSF55729 190 347 6.36E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS05200 35f723239c5d778e8ae03e1c102c157a 377 Gene3D G3DSA:3.40.630.30 25 187 4.3E-4 T 28-03-2018 CWM22_RS05200 35f723239c5d778e8ae03e1c102c157a 377 Gene3D G3DSA:3.40.630.30 188 336 1.2E-27 T 28-03-2018 CWM22_RS05200 35f723239c5d778e8ae03e1c102c157a 377 Pfam PF13480 Acetyltransferase (GNAT) domain 192 317 1.5E-10 T 28-03-2018 CWM22_RS10605 3326027ad25ee42f8870586ee082aaac 107 Hamap MF_00910 Cell division protein FtsL [ftsL]. 25 107 12.821 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CWM22_RS10605 3326027ad25ee42f8870586ee082aaac 107 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 25 105 8.7E-16 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CWM22_RS03885 d89b603f805ac00f64014b2c3d1f8598 364 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 60 116 3.4E-9 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWM22_RS03885 d89b603f805ac00f64014b2c3d1f8598 364 Pfam PF14657 Arm DNA-binding domain 11 52 2.4E-12 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CWM22_RS03885 d89b603f805ac00f64014b2c3d1f8598 364 SUPERFAMILY SSF56349 59 344 2.15E-44 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS03885 d89b603f805ac00f64014b2c3d1f8598 364 Pfam PF00589 Phage integrase family 167 339 2.3E-17 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS03885 d89b603f805ac00f64014b2c3d1f8598 364 Gene3D G3DSA:1.10.443.10 165 355 2.1E-28 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS03885 d89b603f805ac00f64014b2c3d1f8598 364 Gene3D G3DSA:1.10.150.130 54 164 2.5E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWM22_RS10170 66f390ebb05a465645bdcd16cc199899 133 Pfam PF12680 SnoaL-like domain 15 118 5.5E-10 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CWM22_RS10170 66f390ebb05a465645bdcd16cc199899 133 Gene3D G3DSA:3.10.450.50 3 133 2.7E-15 T 28-03-2018 CWM22_RS10170 66f390ebb05a465645bdcd16cc199899 133 SUPERFAMILY SSF54427 9 132 3.76E-27 T 28-03-2018 IPR032710 NTF2-like domain CWM22_RS07545 279a60bcb5c86089a8c23c8eb2839b56 217 Pfam PF08713 DNA alkylation repair enzyme 7 217 1.2E-72 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CWM22_RS07545 279a60bcb5c86089a8c23c8eb2839b56 217 Gene3D G3DSA:1.25.40.290 123 217 5.3E-22 T 28-03-2018 CWM22_RS07545 279a60bcb5c86089a8c23c8eb2839b56 217 SUPERFAMILY SSF48371 10 217 9.78E-55 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWM22_RS07545 279a60bcb5c86089a8c23c8eb2839b56 217 Gene3D G3DSA:1.20.1660.10 4 122 1.6E-33 T 28-03-2018 CWM22_RS06535 9c1526ce5fc958a0b85c3db853e4256a 255 SUPERFAMILY SSF52540 10 217 2.86E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06535 9c1526ce5fc958a0b85c3db853e4256a 255 Gene3D G3DSA:3.40.50.300 1 255 3.1E-27 T 28-03-2018 CWM22_RS06535 9c1526ce5fc958a0b85c3db853e4256a 255 Pfam PF06414 Zeta toxin 28 214 5.4E-55 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 SUPERFAMILY SSF55681 121 442 1.18E-88 T 28-03-2018 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 442 1.3E-78 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 Pfam PF01336 OB-fold nucleic acid binding domain 19 106 3.2E-15 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 Gene3D G3DSA:3.30.930.10 113 448 2.4E-84 T 28-03-2018 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 448 40.087 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 SUPERFAMILY SSF50249 4 113 2.57E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 Gene3D G3DSA:2.40.50.140 6 112 7.4E-18 T 28-03-2018 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 403 417 9.0E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 363 379 9.0E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 9.0E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 9.0E-15 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS03665 74ef98a4ec834e88e82527a62552a04a 448 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 7 446 2.9E-142 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CWM22_RS03565 2b9d8147317436fafd07681a0b122473 286 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 199 1.3E-19 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CWM22_RS03565 2b9d8147317436fafd07681a0b122473 286 Gene3D G3DSA:3.40.50.720 33 282 1.5E-28 T 28-03-2018 CWM22_RS03565 2b9d8147317436fafd07681a0b122473 286 SUPERFAMILY SSF51735 1 237 3.07E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS03565 2b9d8147317436fafd07681a0b122473 286 Gene3D G3DSA:3.40.50.720 1 32 0.017 T 28-03-2018 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 SUPERFAMILY SSF54534 89 243 4.71E-35 T 28-03-2018 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 2.7E-38 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 Gene3D G3DSA:3.30.70.1050 1 119 3.4E-33 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 421 4.2E-44 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 Gene3D G3DSA:1.10.3120.10 213 401 6.5E-48 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 TIGRFAM TIGR00115 tig: trigger factor 13 420 1.3E-124 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 PIRSF PIRSF003095 1 427 8.8E-123 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 Hamap MF_00303 Trigger factor [tig]. 1 427 21.943 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 SUPERFAMILY SSF109998 250 427 9.42E-39 T 28-03-2018 IPR027304 Trigger factor/SurA domain CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 SUPERFAMILY SSF102735 1 129 4.32E-34 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CWM22_RS02030 c0761fbb915a64f28303848ae1aa2276 427 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 230 4.9E-14 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CWM22_RS10280 f263932ef8a53354ca601c4378089c1b 179 Pfam PF03602 Conserved hypothetical protein 95 1 177 8.9E-63 T 28-03-2018 CWM22_RS10280 f263932ef8a53354ca601c4378089c1b 179 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 178 9.3E-52 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CWM22_RS10280 f263932ef8a53354ca601c4378089c1b 179 PIRSF PIRSF004553 1 179 2.5E-58 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CWM22_RS10280 f263932ef8a53354ca601c4378089c1b 179 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 114 120 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWM22_RS10280 f263932ef8a53354ca601c4378089c1b 179 Gene3D G3DSA:3.40.50.150 1 179 4.6E-34 T 28-03-2018 CWM22_RS10280 f263932ef8a53354ca601c4378089c1b 179 SUPERFAMILY SSF53335 1 178 1.02E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 Pfam PF01628 HrcA protein C terminal domain 102 314 2.3E-26 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 326 4.4E-78 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 SUPERFAMILY SSF55781 69 333 7.06E-28 T 28-03-2018 IPR029016 GAF domain-like CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 PIRSF PIRSF005485 1 333 5.7E-72 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 Gene3D G3DSA:3.30.390.60 126 203 3.2E-4 T 28-03-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 SUPERFAMILY SSF46785 1 83 3.69E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 322 25.26 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 Gene3D G3DSA:3.30.450.40 204 335 3.7E-11 T 28-03-2018 IPR029016 GAF domain-like CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 Gene3D G3DSA:1.10.10.10 1 83 2.1E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01880 0f3a2f873b9feb36073ddbb53921e8fa 344 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 1 57 2.9E-8 T 28-03-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 PRINTS PR00471 Acetate kinase family signature 202 223 5.1E-40 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 PRINTS PR00471 Acetate kinase family signature 172 185 5.1E-40 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 PRINTS PR00471 Acetate kinase family signature 301 314 5.1E-40 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 PRINTS PR00471 Acetate kinase family signature 323 339 5.1E-40 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 PRINTS PR00471 Acetate kinase family signature 4 15 5.1E-40 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 PRINTS PR00471 Acetate kinase family signature 376 388 5.1E-40 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 SUPERFAMILY SSF53067 1 194 9.06E-66 T 28-03-2018 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 SUPERFAMILY SSF53067 156 394 1.59E-86 T 28-03-2018 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 Pfam PF00871 Acetokinase family 4 389 2.2E-148 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 Gene3D G3DSA:3.30.420.40 196 395 1.7E-74 T 28-03-2018 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 TIGRFAM TIGR00016 ackA: acetate kinase 2 394 1.5E-151 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 Gene3D G3DSA:3.30.420.40 3 194 1.5E-71 T 28-03-2018 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 PIRSF PIRSF000722 1 395 1.8E-142 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00930 225b7d31b6f95f5a29c52435c3c4d56d 395 Hamap MF_00020 Acetate kinase [ackA]. 1 395 181.702 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWM22_RS00035 e3681e89ba70fa22595870d265b0ee38 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 15 28 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CWM22_RS00035 e3681e89ba70fa22595870d265b0ee38 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 180 37.216 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWM22_RS00035 e3681e89ba70fa22595870d265b0ee38 189 SUPERFAMILY SSF53178 2 188 1.83E-66 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWM22_RS00035 e3681e89ba70fa22595870d265b0ee38 189 Pfam PF01195 Peptidyl-tRNA hydrolase 4 188 1.6E-57 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWM22_RS00035 e3681e89ba70fa22595870d265b0ee38 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 188 7.2E-65 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWM22_RS00035 e3681e89ba70fa22595870d265b0ee38 189 Gene3D G3DSA:3.40.50.1470 1 189 8.3E-68 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWM22_RS00035 e3681e89ba70fa22595870d265b0ee38 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CWM22_RS12290 ccec8029f802f0174f06f2489689322b 286 Pfam PF04203 Sortase family 94 219 2.6E-19 T 28-03-2018 IPR005754 Sortase family CWM22_RS12290 ccec8029f802f0174f06f2489689322b 286 TIGRFAM TIGR01076 sortase_fam: sortase 92 227 1.8E-35 T 28-03-2018 IPR005754 Sortase family CWM22_RS12290 ccec8029f802f0174f06f2489689322b 286 Gene3D G3DSA:2.40.260.10 26 238 5.6E-35 T 28-03-2018 IPR023365 Sortase domain CWM22_RS12290 ccec8029f802f0174f06f2489689322b 286 SUPERFAMILY SSF63817 85 220 5.62E-33 T 28-03-2018 IPR023365 Sortase domain CWM22_RS12910 2baee7e82eaeb913e87da6cac66a9566 559 SUPERFAMILY SSF52540 185 372 2.28E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12910 2baee7e82eaeb913e87da6cac66a9566 559 Pfam PF01580 FtsK/SpoIIIE family 195 341 6.0E-9 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CWM22_RS12910 2baee7e82eaeb913e87da6cac66a9566 559 Gene3D G3DSA:3.40.50.300 102 400 1.0E-14 T 28-03-2018 CWM22_RS02275 524431d81b816131e8b3e2d71799365a 248 Gene3D G3DSA:2.20.25.110 141 206 3.0E-17 T 28-03-2018 CWM22_RS02275 524431d81b816131e8b3e2d71799365a 248 Pfam PF13649 Methyltransferase domain 38 133 1.2E-18 T 28-03-2018 CWM22_RS02275 524431d81b816131e8b3e2d71799365a 248 Gene3D G3DSA:3.40.50.150 2 136 6.9E-23 T 28-03-2018 CWM22_RS02275 524431d81b816131e8b3e2d71799365a 248 SUPERFAMILY SSF53335 4 248 5.23E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02050 f9bc945a30c4b3c14f5d010f3848d52d 534 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 1.9E-248 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CWM22_RS02050 f9bc945a30c4b3c14f5d010f3848d52d 534 SUPERFAMILY SSF52317 289 532 1.25E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS02050 f9bc945a30c4b3c14f5d010f3848d52d 534 Hamap MF_01227 CTP synthase [pyrG]. 2 533 51.312 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CWM22_RS02050 f9bc945a30c4b3c14f5d010f3848d52d 534 SUPERFAMILY SSF52540 1 270 8.13E-125 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02050 f9bc945a30c4b3c14f5d010f3848d52d 534 Gene3D G3DSA:3.40.50.300 1 286 3.9E-133 T 28-03-2018 CWM22_RS02050 f9bc945a30c4b3c14f5d010f3848d52d 534 Pfam PF06418 CTP synthase N-terminus 3 267 4.9E-128 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CWM22_RS02050 f9bc945a30c4b3c14f5d010f3848d52d 534 Pfam PF00117 Glutamine amidotransferase class-I 302 527 4.6E-54 T 28-03-2018 IPR017926 Glutamine amidotransferase CWM22_RS02050 f9bc945a30c4b3c14f5d010f3848d52d 534 Gene3D G3DSA:3.40.50.880 287 534 7.9E-69 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS07000 d5b6a600aaf97044b09dc3a44cb33f6b 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 2.2E-108 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWM22_RS07000 d5b6a600aaf97044b09dc3a44cb33f6b 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWM22_RS07000 d5b6a600aaf97044b09dc3a44cb33f6b 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 5.4E-110 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CWM22_RS07000 d5b6a600aaf97044b09dc3a44cb33f6b 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWM22_RS07000 d5b6a600aaf97044b09dc3a44cb33f6b 303 Gene3D G3DSA:3.40.1190.20 44 303 7.1E-42 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS07000 d5b6a600aaf97044b09dc3a44cb33f6b 303 Pfam PF00294 pfkB family carbohydrate kinase 8 280 3.8E-53 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWM22_RS07000 d5b6a600aaf97044b09dc3a44cb33f6b 303 SUPERFAMILY SSF53613 1 281 5.3E-73 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS07000 d5b6a600aaf97044b09dc3a44cb33f6b 303 PIRSF PIRSF000535 1 303 9.6E-86 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWM22_RS07000 d5b6a600aaf97044b09dc3a44cb33f6b 303 Gene3D G3DSA:2.20.150.10 9 43 4.1E-16 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CWM22_RS11450 0e5cff664412964582af5727f818de98 158 Gene3D G3DSA:3.30.70.260 2 88 9.0E-22 T 28-03-2018 CWM22_RS11450 0e5cff664412964582af5727f818de98 158 SUPERFAMILY SSF55021 1 77 1.15E-17 T 28-03-2018 CWM22_RS11450 0e5cff664412964582af5727f818de98 158 Gene3D G3DSA:3.30.70.1150 89 158 6.5E-29 T 28-03-2018 CWM22_RS11450 0e5cff664412964582af5727f818de98 158 Pfam PF10369 Small subunit of acetolactate synthase 85 157 5.8E-27 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CWM22_RS11450 0e5cff664412964582af5727f818de98 158 SUPERFAMILY SSF55021 80 158 1.16E-23 T 28-03-2018 CWM22_RS11450 0e5cff664412964582af5727f818de98 158 Pfam PF13710 ACT domain 12 74 3.0E-14 T 28-03-2018 CWM22_RS11450 0e5cff664412964582af5727f818de98 158 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 11 77 2.0E-29 T 28-03-2018 CWM22_RS11450 0e5cff664412964582af5727f818de98 158 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 5.7E-55 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CWM22_RS13165 96d04a891be8544ade102422d6da4637 150 Gene3D G3DSA:3.40.50.360 5 150 2.5E-16 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS13165 96d04a891be8544ade102422d6da4637 150 PIRSF PIRSF005087 3 150 7.1E-38 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CWM22_RS13165 96d04a891be8544ade102422d6da4637 150 Pfam PF07972 NrdI Flavodoxin like 7 142 4.8E-39 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CWM22_RS13165 96d04a891be8544ade102422d6da4637 150 SUPERFAMILY SSF52218 2 142 5.59E-20 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS03025 05e3b0cf0a28b67e0d09a1dbe690239d 127 Gene3D G3DSA:3.10.180.10 1 127 1.3E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS03025 05e3b0cf0a28b67e0d09a1dbe690239d 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 5.5E-16 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWM22_RS03025 05e3b0cf0a28b67e0d09a1dbe690239d 127 SUPERFAMILY SSF54593 4 124 1.34E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 104 175 5.4E-13 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 93 638 2.3E-182 T 28-03-2018 IPR011840 Pullulanase, type I CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 Gene3D G3DSA:3.20.20.80 593 646 0.0093 T 28-03-2018 CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 Pfam PF00128 Alpha amylase, catalytic domain 366 555 1.9E-9 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 Pfam PF00128 Alpha amylase, catalytic domain 241 341 1.8E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 SMART SM00642 212 595 1.1E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 Gene3D G3DSA:3.20.20.80 190 592 2.3E-75 T 28-03-2018 CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 SUPERFAMILY SSF51445 201 602 1.0E-106 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 Gene3D G3DSA:2.60.40.10 99 189 2.2E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS13160 1ce3aa37dda3eb00c2b319a9cc2ae54a 683 SUPERFAMILY SSF81296 100 192 8.2E-22 T 28-03-2018 IPR014756 Immunoglobulin E-set CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 SUPERFAMILY SSF52540 6 222 4.87E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 Gene3D G3DSA:3.40.50.300 78 193 9.2E-33 T 28-03-2018 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 Gene3D G3DSA:2.40.30.10 194 302 4.5E-30 T 28-03-2018 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 Gene3D G3DSA:3.40.50.300 1 77 8.9E-11 T 28-03-2018 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 2.0E-13 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 Pfam PF03144 Elongation factor Tu domain 2 228 297 3.7E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 5.4E-59 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 PRINTS PR00315 GTP-binding elongation factor signature 61 69 2.0E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 PRINTS PR00315 GTP-binding elongation factor signature 81 91 2.0E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.0E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 PRINTS PR00315 GTP-binding elongation factor signature 97 108 2.0E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 PRINTS PR00315 GTP-binding elongation factor signature 134 143 2.0E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 7.3E-221 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 398 59.189 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 SUPERFAMILY SSF50465 306 397 2.22E-35 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 Gene3D G3DSA:2.40.30.10 304 396 8.0E-31 T 28-03-2018 CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 SUPERFAMILY SSF50447 208 305 1.08E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS10005 b817677f0a0f12277f6dfc7f59d85558 398 Pfam PF03143 Elongation factor Tu C-terminal domain 302 396 4.2E-32 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CWM22_RS12430 1f8f213f2d4957d6d71bb2ae35d971ce 300 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 269 5.0E-110 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CWM22_RS12430 1f8f213f2d4957d6d71bb2ae35d971ce 300 SUPERFAMILY SSF53448 2 273 2.48E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS12430 1f8f213f2d4957d6d71bb2ae35d971ce 300 Gene3D G3DSA:3.90.550.10 1 282 5.5E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS12430 1f8f213f2d4957d6d71bb2ae35d971ce 300 Pfam PF00483 Nucleotidyl transferase 7 268 1.2E-33 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 SUPERFAMILY SSF51261 490 644 2.44E-51 T 28-03-2018 IPR011055 Duplicated hybrid motif CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 468 7.3E-221 T 28-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 561 573 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 Gene3D G3DSA:2.70.70.10 485 646 1.8E-55 T 28-03-2018 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 499 619 2.3E-41 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 498 622 4.9E-49 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 Pfam PF00367 phosphotransferase system, EIIB 9 42 4.4E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 Pfam PF02378 Phosphotransferase system, EIIC 111 412 1.6E-37 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 SUPERFAMILY SSF55604 8 81 4.58E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWM22_RS01400 a4480e09e8c1311fc8741c428043e047 647 Gene3D G3DSA:3.30.1360.60 3 77 5.0E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 Pfam PF00154 recA bacterial DNA recombination protein 22 287 8.2E-138 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 19 342 1.0E-159 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 Gene3D G3DSA:3.30.250.10 288 344 6.5E-25 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 Gene3D G3DSA:3.40.50.300 41 287 1.6E-39 T 28-03-2018 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 SUPERFAMILY SSF52540 19 286 1.61E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 Hamap MF_00268 Protein RecA [recA]. 20 348 50.563 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 PRINTS PR00142 RecA protein signature 316 333 1.4E-80 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 PRINTS PR00142 RecA protein signature 108 137 1.4E-80 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 PRINTS PR00142 RecA protein signature 142 171 1.4E-80 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 PRINTS PR00142 RecA protein signature 225 253 1.4E-80 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 PRINTS PR00142 RecA protein signature 262 291 1.4E-80 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 PRINTS PR00142 RecA protein signature 180 209 1.4E-80 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 SMART SM00382 72 243 1.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 SUPERFAMILY SSF54752 287 345 2.22E-20 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CWM22_RS00455 f2d7cc92b6a356a04b1d9bdde10db701 383 ProSitePatterns PS00321 recA signature. 228 236 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CWM22_RS05255 1f11dba89b60ee6053a3e7c69f0f4585 334 Gene3D G3DSA:3.90.550.10 5 294 5.7E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05255 1f11dba89b60ee6053a3e7c69f0f4585 334 Pfam PF00535 Glycosyl transferase family 2 8 122 5.2E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS05255 1f11dba89b60ee6053a3e7c69f0f4585 334 SUPERFAMILY SSF53448 5 228 8.63E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 264 281 4.0E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 163 175 4.0E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 213 229 4.0E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 67 81 4.0E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 96 106 4.0E-22 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 Gene3D G3DSA:3.40.50.150 76 290 1.4E-57 T 28-03-2018 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 386 432 3.1E-15 T 28-03-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 Pfam PF01189 16S rRNA methyltransferase RsmB/F 87 280 1.8E-46 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 308 368 6.6E-21 T 28-03-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 3 81 1.4E-17 T 28-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CWM22_RS05030 6f502bf1da10e8a6bd7d88ca59fcc31d 433 SUPERFAMILY SSF53335 2 280 3.58E-64 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS11235 7c8f206c8fd74bd2bfb7d92408bbf473 287 SUPERFAMILY SSF47413 3 63 3.49E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS11235 7c8f206c8fd74bd2bfb7d92408bbf473 287 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 63 284 1.5E-45 T 28-03-2018 IPR010057 Transcription activator MutR, C-terminal CWM22_RS11235 7c8f206c8fd74bd2bfb7d92408bbf473 287 Pfam PF01381 Helix-turn-helix 9 61 1.1E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS11235 7c8f206c8fd74bd2bfb7d92408bbf473 287 SMART SM00530 7 61 1.3E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS11235 7c8f206c8fd74bd2bfb7d92408bbf473 287 Gene3D G3DSA:1.10.260.40 1 147 1.4E-12 T 28-03-2018 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 SUPERFAMILY SSF53335 1 207 4.78E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 SUPERFAMILY SSF53335 377 439 4.78E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 SUPERFAMILY SSF53335 236 295 4.78E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.90.120.10 232 265 0.13 T 28-03-2018 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.90.120.10 266 306 0.056 T 28-03-2018 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.40.50.150 1 179 2.4E-64 T 28-03-2018 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.90.120.10 180 231 1.2E-4 T 28-03-2018 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.90.120.10 307 426 1.8E-17 T 28-03-2018 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 438 7.4E-88 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 437 2.0E-91 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 69 81 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 154 167 6.2E-18 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 6.2E-18 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS05490 57453e840ec8810835cdf679006da8f7 451 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 108 122 6.2E-18 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 SUPERFAMILY SSF53335 1 207 4.78E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 SUPERFAMILY SSF53335 377 439 4.78E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 SUPERFAMILY SSF53335 236 295 4.78E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.90.120.10 232 265 0.13 T 28-03-2018 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.90.120.10 266 306 0.056 T 28-03-2018 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.40.50.150 1 179 2.4E-64 T 28-03-2018 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.90.120.10 180 231 1.2E-4 T 28-03-2018 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 Gene3D G3DSA:3.90.120.10 307 426 1.8E-17 T 28-03-2018 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 438 7.4E-88 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 437 2.0E-91 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 69 81 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 154 167 6.2E-18 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 6.2E-18 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06290 57453e840ec8810835cdf679006da8f7 451 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 108 122 6.2E-18 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS05635 2b239c6003015bdf1c02b020288867a5 31 ProDom PD018707 LEADER PEPTIDE METHYLASE PLASMID RESISTANCE RRNA METHYLTRANSFERASE ERMB 23S ANTIBIOTIC 1 31 9.0E-11 T 28-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 CWM22_RS05635 2b239c6003015bdf1c02b020288867a5 31 Pfam PF06308 23S rRNA methylase leader peptide (ErmC) 1 31 7.9E-25 T 28-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 CWM22_RS06495 2b239c6003015bdf1c02b020288867a5 31 ProDom PD018707 LEADER PEPTIDE METHYLASE PLASMID RESISTANCE RRNA METHYLTRANSFERASE ERMB 23S ANTIBIOTIC 1 31 9.0E-11 T 28-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 CWM22_RS06495 2b239c6003015bdf1c02b020288867a5 31 Pfam PF06308 23S rRNA methylase leader peptide (ErmC) 1 31 7.9E-25 T 28-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 CWM22_RS05520 2b239c6003015bdf1c02b020288867a5 31 ProDom PD018707 LEADER PEPTIDE METHYLASE PLASMID RESISTANCE RRNA METHYLTRANSFERASE ERMB 23S ANTIBIOTIC 1 31 9.0E-11 T 28-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 CWM22_RS05520 2b239c6003015bdf1c02b020288867a5 31 Pfam PF06308 23S rRNA methylase leader peptide (ErmC) 1 31 7.9E-25 T 28-03-2018 IPR009391 23S rRNA methylase leader peptide GO:0046677 CWM22_RS04310 4f3005c38eb5204784d40a42fe33bbd5 334 Pfam PF10282 Lactonase, 7-bladed beta-propeller 2 333 7.7E-116 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CWM22_RS04310 4f3005c38eb5204784d40a42fe33bbd5 334 SUPERFAMILY SSF51004 21 333 5.23E-38 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CWM22_RS04310 4f3005c38eb5204784d40a42fe33bbd5 334 Gene3D G3DSA:2.130.10.10 1 334 2.2E-41 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CWM22_RS10080 85b3c3c829b7e680f4059e888b0fdbf9 231 Pfam PF00005 ABC transporter 25 173 4.7E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS10080 85b3c3c829b7e680f4059e888b0fdbf9 231 Gene3D G3DSA:3.40.50.300 1 231 9.7E-67 T 28-03-2018 CWM22_RS10080 85b3c3c829b7e680f4059e888b0fdbf9 231 SUPERFAMILY SSF52540 5 230 7.79E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10080 85b3c3c829b7e680f4059e888b0fdbf9 231 SMART SM00382 34 221 1.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS10080 85b3c3c829b7e680f4059e888b0fdbf9 231 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS02870 539e72fef50a5686204d0dcc229296be 76 Pfam PF08796 Protein of unknown function (DUF1797) 8 75 3.2E-23 T 28-03-2018 IPR014904 Protein of unknown function DUF1797 CWM22_RS02870 539e72fef50a5686204d0dcc229296be 76 PIRSF PIRSF037356 1 76 2.3E-29 T 28-03-2018 IPR014904 Protein of unknown function DUF1797 CWM22_RS02870 539e72fef50a5686204d0dcc229296be 76 SUPERFAMILY SSF143567 3 76 2.48E-23 T 28-03-2018 CWM22_RS02970 b5c35560d20f0ead6272076f00b863f8 277 SUPERFAMILY SSF82549 1 276 8.11E-83 T 28-03-2018 CWM22_RS02970 b5c35560d20f0ead6272076f00b863f8 277 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 275 2.8E-88 T 28-03-2018 IPR003797 DegV CWM22_RS02970 b5c35560d20f0ead6272076f00b863f8 277 Gene3D G3DSA:3.30.1180.10 153 277 1.5E-28 T 28-03-2018 CWM22_RS02970 b5c35560d20f0ead6272076f00b863f8 277 Gene3D G3DSA:3.40.50.10170 1 152 2.3E-45 T 28-03-2018 CWM22_RS02970 b5c35560d20f0ead6272076f00b863f8 277 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 274 4.4E-90 T 28-03-2018 IPR003797 DegV CWM22_RS04050 b6b4f1f4b4f21ff5456e18882f5ecd76 364 SMART SM00470 7 93 3.3E-14 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS04050 b6b4f1f4b4f21ff5456e18882f5ecd76 364 Pfam PF14386 Domain of unknown function (DUF4417) 173 346 3.0E-63 T 28-03-2018 IPR025530 Protein of unknown function DUF4417 CWM22_RS04050 b6b4f1f4b4f21ff5456e18882f5ecd76 364 Gene3D G3DSA:3.90.1530.10 3 95 2.6E-17 T 28-03-2018 CWM22_RS04050 b6b4f1f4b4f21ff5456e18882f5ecd76 364 Pfam PF02195 ParB-like nuclease domain 8 92 1.4E-12 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS04050 b6b4f1f4b4f21ff5456e18882f5ecd76 364 SUPERFAMILY SSF110849 5 122 1.33E-26 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 9 659 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 661 43.942 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 SMART SM00487 14 430 2.0E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 Pfam PF04851 Type III restriction enzyme, res subunit 21 143 1.3E-12 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 SUPERFAMILY SSF52540 8 419 7.25E-140 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 Pfam PF00271 Helicase conserved C-terminal domain 445 549 5.5E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 SUPERFAMILY SSF52540 331 620 3.29E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 SMART SM00490 464 550 3.0E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 Gene3D G3DSA:4.10.860.10 601 661 5.1E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 Gene3D G3DSA:3.40.50.300 421 593 1.6E-31 T 28-03-2018 CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 Pfam PF12344 Ultra-violet resistance protein B 556 598 8.0E-24 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 Pfam PF02151 UvrB/uvrC motif 626 660 4.4E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 SUPERFAMILY SSF46600 616 660 5.89E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWM22_RS05455 fe51d5c5426f932ad77516c576a5ae59 661 Gene3D G3DSA:3.40.50.300 16 420 1.8E-31 T 28-03-2018 CWM22_RS03235 31f1e9fb8a3213b547a868f1d0185297 252 SUPERFAMILY SSF52540 4 230 1.9E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03235 31f1e9fb8a3213b547a868f1d0185297 252 Gene3D G3DSA:3.40.50.300 1 242 5.5E-60 T 28-03-2018 CWM22_RS03235 31f1e9fb8a3213b547a868f1d0185297 252 Pfam PF00005 ABC transporter 25 173 2.3E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS03235 31f1e9fb8a3213b547a868f1d0185297 252 SMART SM00382 34 222 9.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS03235 31f1e9fb8a3213b547a868f1d0185297 252 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 SUPERFAMILY SSF50447 263 400 5.81E-35 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 2.9E-70 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Gene3D G3DSA:3.30.230.10 490 611 1.0E-42 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Gene3D G3DSA:3.40.50.300 1 285 7.0E-68 T 28-03-2018 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Gene3D G3DSA:3.30.70.870 399 489 6.7E-34 T 28-03-2018 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Pfam PF00679 Elongation factor G C-terminus 599 684 3.4E-30 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Pfam PF14492 Elongation Factor G, domain II 402 475 2.5E-33 T 28-03-2018 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 689 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Gene3D G3DSA:2.40.30.10 286 398 9.5E-30 T 28-03-2018 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 SUPERFAMILY SSF54980 601 688 3.6E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 SUPERFAMILY SSF54980 400 478 9.35E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Gene3D G3DSA:3.30.70.240 612 689 1.4E-32 T 28-03-2018 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 SMART SM00889 478 596 2.1E-71 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Pfam PF03144 Elongation factor Tu domain 2 322 389 7.4E-15 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 7.5E-42 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 SUPERFAMILY SSF54211 477 597 1.42E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 SUPERFAMILY SSF52540 6 280 1.85E-112 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 110.335 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 Pfam PF03764 Elongation factor G, domain IV 477 596 7.4E-46 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWM22_RS01025 c01742df24827de5d5c16c16ee7243d7 693 SMART SM00838 598 685 1.8E-51 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWM22_RS11420 c43902086b18ce9184753c5282828eae 521 SMART SM00062 27 264 1.7E-30 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS11420 c43902086b18ce9184753c5282828eae 521 SUPERFAMILY SSF53850 1 254 2.41E-43 T 28-03-2018 CWM22_RS11420 c43902086b18ce9184753c5282828eae 521 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 255 3.1E-35 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS11420 c43902086b18ce9184753c5282828eae 521 Gene3D G3DSA:3.40.190.10 19 140 5.7E-26 T 28-03-2018 CWM22_RS11420 c43902086b18ce9184753c5282828eae 521 Gene3D G3DSA:1.10.3720.10 214 508 4.5E-45 T 28-03-2018 CWM22_RS11420 c43902086b18ce9184753c5282828eae 521 SUPERFAMILY SSF161098 289 491 1.7E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS11420 c43902086b18ce9184753c5282828eae 521 Gene3D G3DSA:3.40.190.10 141 213 2.6E-10 T 28-03-2018 CWM22_RS11420 c43902086b18ce9184753c5282828eae 521 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 289 397 1.2E-21 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWM22_RS11420 c43902086b18ce9184753c5282828eae 521 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 336 500 4.3E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS03755 901798605d00d89fb50656f599debbe1 234 Gene3D G3DSA:3.40.50.1360 6 234 5.1E-61 T 28-03-2018 CWM22_RS03755 901798605d00d89fb50656f599debbe1 234 SUPERFAMILY SSF100950 1 233 7.85E-80 T 28-03-2018 CWM22_RS03755 901798605d00d89fb50656f599debbe1 234 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 112 130 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CWM22_RS03755 901798605d00d89fb50656f599debbe1 234 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 233 39.07 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CWM22_RS03755 901798605d00d89fb50656f599debbe1 234 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 25 221 2.1E-14 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 319 334 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Gene3D G3DSA:2.40.50.140 310 378 4.6E-33 T 28-03-2018 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 306 2.2E-117 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 SUPERFAMILY SSF52113 580 651 1.03E-18 T 28-03-2018 IPR001357 BRCT domain CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Gene3D G3DSA:3.30.1490.70 227 309 4.3E-25 T 28-03-2018 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 SMART SM00292 579 652 3.6E-7 T 28-03-2018 IPR001357 BRCT domain CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 SUPERFAMILY SSF47781 391 571 1.06E-57 T 28-03-2018 IPR010994 RuvA domain 2-like CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Pfam PF14520 Helix-hairpin-helix domain 432 487 3.5E-7 T 28-03-2018 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 SMART SM00278 466 485 7.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 SMART SM00278 432 451 100.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 SMART SM00278 530 549 690.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 582 650 7.8E-13 T 28-03-2018 IPR001357 BRCT domain CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Hamap MF_01588 DNA ligase [ligA]. 1 652 48.777 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Gene3D G3DSA:1.10.150.20 418 491 1.7E-26 T 28-03-2018 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Gene3D G3DSA:3.40.50.10190 558 652 3.5E-22 T 28-03-2018 IPR001357 BRCT domain CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Pfam PF12826 Helix-hairpin-helix motif 496 558 3.0E-18 T 28-03-2018 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 310 386 2.9E-34 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Gene3D G3DSA:3.30.470.30 113 226 2.3E-42 T 28-03-2018 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 394 419 4.3E-8 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 SMART SM00532 2 434 3.3E-239 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 PIRSF PIRSF001604 1 652 1.1E-242 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Gene3D G3DSA:1.10.150.20 493 557 1.2E-20 T 28-03-2018 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 SUPERFAMILY SSF50249 306 388 1.66E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 Gene3D G3DSA:1.10.287.610 1 64 5.5E-24 T 28-03-2018 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 SUPERFAMILY SSF56091 2 306 1.41E-114 T 28-03-2018 CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 109 138 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CWM22_RS08200 55a0fef91bfe70bec35a7fde8aa4a650 652 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 9 647 2.9E-245 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CWM22_RS05720 a38dbfa57c953feb32cf9d3161c4ebd0 143 SUPERFAMILY SSF88659 70 141 1.59E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS05720 a38dbfa57c953feb32cf9d3161c4ebd0 143 Gene3D G3DSA:1.10.10.60 6 81 3.0E-4 T 28-03-2018 CWM22_RS05720 a38dbfa57c953feb32cf9d3161c4ebd0 143 Gene3D G3DSA:1.10.10.10 82 142 9.7E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06440 a38dbfa57c953feb32cf9d3161c4ebd0 143 SUPERFAMILY SSF88659 70 141 1.59E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS06440 a38dbfa57c953feb32cf9d3161c4ebd0 143 Gene3D G3DSA:1.10.10.60 6 81 3.0E-4 T 28-03-2018 CWM22_RS06440 a38dbfa57c953feb32cf9d3161c4ebd0 143 Gene3D G3DSA:1.10.10.10 82 142 9.7E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12105 607ec0a2e1ec42c3f81a1b18f79faf38 225 Gene3D G3DSA:1.10.10.60 162 220 8.9E-6 T 28-03-2018 CWM22_RS12105 607ec0a2e1ec42c3f81a1b18f79faf38 225 Gene3D G3DSA:3.40.50.1390 8 126 3.4E-24 T 28-03-2018 CWM22_RS12105 607ec0a2e1ec42c3f81a1b18f79faf38 225 Pfam PF00239 Resolvase, N terminal domain 15 156 3.2E-30 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS12105 607ec0a2e1ec42c3f81a1b18f79faf38 225 SMART SM00857 15 157 6.4E-38 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS12105 607ec0a2e1ec42c3f81a1b18f79faf38 225 Gene3D G3DSA:1.20.5.40 127 155 9.3E-11 T 28-03-2018 CWM22_RS12105 607ec0a2e1ec42c3f81a1b18f79faf38 225 SUPERFAMILY SSF53041 15 156 6.67E-30 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS08085 07ba7c60debd46ad607788ae68afc1f4 596 SUPERFAMILY SSF51445 11 394 8.95E-77 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS08085 07ba7c60debd46ad607788ae68afc1f4 596 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 30 349 1.2E-59 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CWM22_RS08085 07ba7c60debd46ad607788ae68afc1f4 596 Gene3D G3DSA:3.20.20.300 16 386 7.9E-67 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CWM22_RS08085 07ba7c60debd46ad607788ae68afc1f4 596 Gene3D G3DSA:3.40.50.1700 387 589 1.7E-10 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 SUPERFAMILY SSF53335 639 869 1.56E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 Pfam PF02384 N-6 DNA Methylase 671 868 3.2E-11 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 Pfam PF00176 SNF2 family N-terminal domain 1469 1801 4.9E-13 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 SMART SM00487 1448 1712 9.8E-18 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 Gene3D G3DSA:3.40.50.150 679 1119 1.4E-28 T 28-03-2018 CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 Gene3D G3DSA:3.40.50.10810 1431 1748 4.3E-28 T 28-03-2018 CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 SUPERFAMILY SSF52540 1413 1562 1.02E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 SUPERFAMILY SSF52540 1613 1706 1.02E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 791 815 6.0E-7 T 28-03-2018 CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 706 720 6.0E-7 T 28-03-2018 CWM22_RS06375 46297daa3105b4fd2c2e52ef5a6e13f6 1820 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 767 779 6.0E-7 T 28-03-2018 CWM22_RS12990 e6eea77535d4fe1697696ffa7f4d126a 163 Gene3D G3DSA:3.40.630.30 1 161 8.7E-16 T 28-03-2018 CWM22_RS12990 e6eea77535d4fe1697696ffa7f4d126a 163 SUPERFAMILY SSF55729 3 154 7.27E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS12990 e6eea77535d4fe1697696ffa7f4d126a 163 Pfam PF13302 Acetyltransferase (GNAT) domain 2 147 3.5E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS06940 82c7993ded199bada90f4e509c7fad91 279 Gene3D G3DSA:3.30.572.10 6 279 1.5E-61 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWM22_RS06940 82c7993ded199bada90f4e509c7fad91 279 Pfam PF00303 Thymidylate synthase 8 279 8.4E-64 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWM22_RS06940 82c7993ded199bada90f4e509c7fad91 279 ProSitePatterns PS00091 Thymidylate synthase active site. 133 162 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWM22_RS06940 82c7993ded199bada90f4e509c7fad91 279 PRINTS PR00108 Thymidylate synthase family signature 54 75 8.5E-14 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWM22_RS06940 82c7993ded199bada90f4e509c7fad91 279 PRINTS PR00108 Thymidylate synthase family signature 122 141 8.5E-14 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWM22_RS06940 82c7993ded199bada90f4e509c7fad91 279 PRINTS PR00108 Thymidylate synthase family signature 171 197 8.5E-14 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWM22_RS06940 82c7993ded199bada90f4e509c7fad91 279 PRINTS PR00108 Thymidylate synthase family signature 209 226 8.5E-14 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWM22_RS06940 82c7993ded199bada90f4e509c7fad91 279 Hamap MF_00008 Thymidylate synthase [thyA]. 5 279 33.666 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWM22_RS06940 82c7993ded199bada90f4e509c7fad91 279 SUPERFAMILY SSF55831 3 278 2.09E-72 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWM22_RS12610 58e4d49f47e9bec098dd9aee84520d45 613 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 22 314 6.3E-31 T 28-03-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain CWM22_RS12610 58e4d49f47e9bec098dd9aee84520d45 613 Gene3D G3DSA:3.20.20.190 359 599 1.6E-56 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS12610 58e4d49f47e9bec098dd9aee84520d45 613 SUPERFAMILY SSF51695 365 588 4.71E-54 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS12610 58e4d49f47e9bec098dd9aee84520d45 613 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 369 587 3.6E-27 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CWM22_RS06855 1f4e28ce678b7387c1deb2e758433bd5 199 SUPERFAMILY SSF53955 32 148 1.29E-10 T 28-03-2018 IPR023346 Lysozyme-like domain CWM22_RS06855 1f4e28ce678b7387c1deb2e758433bd5 199 Gene3D G3DSA:1.10.530.10 21 191 7.6E-11 T 28-03-2018 CWM22_RS06855 1f4e28ce678b7387c1deb2e758433bd5 199 Pfam PF13702 Lysozyme-like 28 189 8.6E-60 T 28-03-2018 CWM22_RS10960 eb9c25a611498d8fdc0cce69a24a352a 263 Gene3D G3DSA:3.90.226.10 1 263 2.7E-63 T 28-03-2018 CWM22_RS10960 eb9c25a611498d8fdc0cce69a24a352a 263 SUPERFAMILY SSF52096 1 262 1.84E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWM22_RS10960 eb9c25a611498d8fdc0cce69a24a352a 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 262 2.3E-43 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CWM22_RS10345 a109f4ddeb4522088993db828420c060 599 SUPERFAMILY SSF52266 416 588 1.31E-8 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWM22_RS10345 a109f4ddeb4522088993db828420c060 599 Gene3D G3DSA:3.40.50.1110 394 592 8.9E-13 T 28-03-2018 CWM22_RS10345 a109f4ddeb4522088993db828420c060 599 Pfam PF01757 Acyltransferase family 4 346 7.0E-24 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 PRINTS PR00723 Subtilisin serine protease family (S8) signature 246 265 7.8E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 PRINTS PR00723 Subtilisin serine protease family (S8) signature 648 664 7.8E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 PRINTS PR00723 Subtilisin serine protease family (S8) signature 307 320 7.8E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 SUPERFAMILY SSF52743 231 462 9.3E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 SUPERFAMILY SSF52743 611 724 9.3E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 SUPERFAMILY SSF52025 583 667 3.4E-8 T 28-03-2018 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 SUPERFAMILY SSF52025 477 545 3.4E-8 T 28-03-2018 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 Pfam PF04650 YSIRK type signal peptide 9 31 1.8E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 9 41 4.0E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 Gene3D G3DSA:3.40.50.200 215 729 1.4E-69 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 251 262 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 Gene3D G3DSA:2.60.40.1710 730 861 1.1E-17 T 28-03-2018 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 Pfam PF00082 Subtilase family 246 715 1.8E-53 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 311 321 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 649 659 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CWM22_RS11950 f446babf3ab5a11af3397df3fa8b59b9 1694 Pfam PF06280 Fn3-like domain 737 852 1.0E-23 T 28-03-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 CWM22_RS00795 5aca6435ae4ed889353f5503f03d03ad 109 Pfam PF01381 Helix-turn-helix 13 65 7.0E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS00795 5aca6435ae4ed889353f5503f03d03ad 109 Gene3D G3DSA:1.10.260.40 8 105 3.3E-17 T 28-03-2018 CWM22_RS00795 5aca6435ae4ed889353f5503f03d03ad 109 SUPERFAMILY SSF47413 5 75 1.69E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS00795 5aca6435ae4ed889353f5503f03d03ad 109 SMART SM00530 12 67 1.8E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS02165 eebd6f7a796d4363ec5e5842aa79164d 479 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 474 1.5E-163 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CWM22_RS02165 eebd6f7a796d4363ec5e5842aa79164d 479 SMART SM00845 327 474 2.9E-65 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CWM22_RS02165 eebd6f7a796d4363ec5e5842aa79164d 479 Gene3D G3DSA:1.10.10.410 414 475 1.1E-14 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CWM22_RS02165 eebd6f7a796d4363ec5e5842aa79164d 479 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 475 36.853 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CWM22_RS02165 eebd6f7a796d4363ec5e5842aa79164d 479 SUPERFAMILY SSF89095 298 401 2.22E-31 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CWM22_RS02165 eebd6f7a796d4363ec5e5842aa79164d 479 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 143 157 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CWM22_RS02165 eebd6f7a796d4363ec5e5842aa79164d 479 SUPERFAMILY SSF55931 4 295 6.34E-119 T 28-03-2018 CWM22_RS02165 eebd6f7a796d4363ec5e5842aa79164d 479 Pfam PF02934 GatB/GatE catalytic domain 6 288 7.1E-109 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CWM22_RS02165 eebd6f7a796d4363ec5e5842aa79164d 479 Pfam PF02637 GatB domain 327 474 3.8E-48 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CWM22_RS11855 80a28e4a77ed9d6208e217e73561cf24 182 SMART SM01120 21 179 6.3E-73 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWM22_RS11855 80a28e4a77ed9d6208e217e73561cf24 182 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 2 178 2.0E-69 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 CWM22_RS11855 80a28e4a77ed9d6208e217e73561cf24 182 Pfam PF02734 DAK2 domain 21 178 1.1E-48 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWM22_RS11855 80a28e4a77ed9d6208e217e73561cf24 182 SUPERFAMILY SSF101473 3 180 6.41E-58 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 Gene3D G3DSA:2.30.30.30 2 61 5.3E-22 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 5.9E-24 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 SMART SM00841 129 184 3.2E-29 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 8.9E-16 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 PIRSF PIRSF005901 1 185 1.5E-62 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 46.68 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 4.0E-22 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 SUPERFAMILY SSF50249 128 185 2.57E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 SUPERFAMILY SSF50249 64 126 3.6E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 Gene3D G3DSA:2.40.50.140 65 126 5.1E-18 T 28-03-2018 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 SMART SM01185 67 121 1.9E-19 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 Gene3D G3DSA:2.40.50.140 129 184 6.8E-23 T 28-03-2018 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 7.6E-67 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CWM22_RS11025 df74ddfc74c6850cf5f9dca6169f2ad0 185 SUPERFAMILY SSF50104 1 63 5.11E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWM22_RS12090 a63b76e89bdbb749c26294eee88abb44 219 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWM22_RS12090 a63b76e89bdbb749c26294eee88abb44 219 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 202 4.3E-77 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWM22_RS12090 a63b76e89bdbb749c26294eee88abb44 219 SUPERFAMILY SSF51366 1 211 1.21E-69 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWM22_RS12090 a63b76e89bdbb749c26294eee88abb44 219 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 213 2.8E-80 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWM22_RS12090 a63b76e89bdbb749c26294eee88abb44 219 Gene3D G3DSA:3.20.20.70 1 218 2.1E-83 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS12090 a63b76e89bdbb749c26294eee88abb44 219 PIRSF PIRSF001461 1 219 1.7E-85 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWM22_RS12935 0bd4b6bc3987a8cc670825c215696401 136 SMART SM00530 5 60 3.1E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12935 0bd4b6bc3987a8cc670825c215696401 136 SUPERFAMILY SSF47413 1 65 2.76E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS12935 0bd4b6bc3987a8cc670825c215696401 136 Gene3D G3DSA:1.10.260.40 1 133 1.1E-17 T 28-03-2018 CWM22_RS12935 0bd4b6bc3987a8cc670825c215696401 136 Pfam PF01381 Helix-turn-helix 6 60 1.1E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 Gene3D G3DSA:3.90.120.10 185 372 1.4E-17 T 28-03-2018 CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 384 4.1E-89 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 366 384 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 3.7E-18 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 154 167 3.7E-18 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 108 122 3.7E-18 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 Gene3D G3DSA:3.40.50.150 1 184 2.9E-66 T 28-03-2018 CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 SUPERFAMILY SSF53335 2 264 1.11E-86 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 SUPERFAMILY SSF53335 323 385 1.11E-86 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 384 1.3E-86 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06140 b510441b9c52edc140c2e0cea4f33db2 394 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 69 81 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 Gene3D G3DSA:3.30.1490.20 129 201 1.7E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 3.4E-205 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 SMART SM00878 337 444 2.5E-57 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 Gene3D G3DSA:3.40.50.20 1 128 1.3E-52 T 28-03-2018 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 2.2E-76 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.1E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 SUPERFAMILY SSF52440 1 113 5.18E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 3.2E-37 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 SUPERFAMILY SSF56059 83 353 2.47E-68 T 28-03-2018 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 Gene3D G3DSA:3.30.470.20 204 447 1.9E-97 T 28-03-2018 CWM22_RS10910 2d851f1b3c5f01f7dba19afed8af9648 455 SUPERFAMILY SSF51246 332 445 3.45E-40 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWM22_RS05320 e22acba64c85bbca90137fe57f1931f2 212 SUPERFAMILY SSF46785 10 81 9.66E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05320 e22acba64c85bbca90137fe57f1931f2 212 Gene3D G3DSA:1.10.10.10 7 74 4.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05320 e22acba64c85bbca90137fe57f1931f2 212 Pfam PF06971 Putative DNA-binding protein N-terminus 9 56 1.7E-16 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CWM22_RS05320 e22acba64c85bbca90137fe57f1931f2 212 SMART SM00881 82 184 5.1E-10 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CWM22_RS05320 e22acba64c85bbca90137fe57f1931f2 212 Gene3D G3DSA:3.40.50.720 75 191 3.2E-15 T 28-03-2018 CWM22_RS05320 e22acba64c85bbca90137fe57f1931f2 212 Pfam PF02629 CoA binding domain 85 183 5.1E-25 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CWM22_RS05320 e22acba64c85bbca90137fe57f1931f2 212 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 4 212 36.784 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CWM22_RS05320 e22acba64c85bbca90137fe57f1931f2 212 SUPERFAMILY SSF51735 87 210 5.77E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS05370 2b54bbb804202dca2202499586aad6bf 579 Pfam PF00664 ABC transporter transmembrane region 16 283 7.6E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS05370 2b54bbb804202dca2202499586aad6bf 579 Gene3D G3DSA:1.20.1560.10 1 318 4.1E-61 T 28-03-2018 CWM22_RS05370 2b54bbb804202dca2202499586aad6bf 579 SMART SM00382 359 544 8.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05370 2b54bbb804202dca2202499586aad6bf 579 Pfam PF00005 ABC transporter 350 498 2.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05370 2b54bbb804202dca2202499586aad6bf 579 SUPERFAMILY SSF90123 2 312 3.01E-63 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS05370 2b54bbb804202dca2202499586aad6bf 579 Gene3D G3DSA:3.40.50.300 319 574 3.1E-60 T 28-03-2018 CWM22_RS05370 2b54bbb804202dca2202499586aad6bf 579 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05370 2b54bbb804202dca2202499586aad6bf 579 SUPERFAMILY SSF52540 333 568 2.07E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 SUPERFAMILY SSF74914 298 601 6.8E-49 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 Gene3D G3DSA:3.10.20.320 854 937 2.4E-7 T 28-03-2018 CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1401 1432 1.3E-5 T 28-03-2018 CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 Pfam PF16364 Cell surface antigen C-terminus 1212 1376 1.8E-21 T 28-03-2018 IPR032300 Cell surface antigen, C-terminal CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 Pfam PF08363 Glucan-binding protein C 318 582 1.3E-37 T 28-03-2018 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 Pfam PF00746 LPXTG cell wall anchor motif 1399 1434 6.9E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 1034 1210 3.4E-36 T 28-03-2018 IPR026345 Adhesin isopeptide-forming adherence domain CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 Gene3D G3DSA:3.10.20.320 938 1037 1.0E-13 T 28-03-2018 CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 Pfam PF06458 MucBP domain 942 1016 3.9E-8 T 28-03-2018 IPR009459 MucBP domain CWM22_RS09060 239ea24f1fd17c4e98ea8fee79b55a0e 1437 Pfam PF06458 MucBP domain 859 932 2.6E-5 T 28-03-2018 IPR009459 MucBP domain CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 Pfam PF06574 FAD synthetase 14 165 2.7E-43 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 303 2.1E-77 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 Pfam PF01687 Riboflavin kinase 182 301 5.4E-30 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 SUPERFAMILY SSF82114 172 304 9.81E-44 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 SUPERFAMILY SSF52374 16 174 1.75E-29 T 28-03-2018 CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 Gene3D G3DSA:3.40.50.620 1 177 5.4E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 86 5.8E-10 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 Gene3D G3DSA:2.40.30.30 178 305 9.4E-36 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 SMART SM00904 181 305 2.7E-51 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWM22_RS05005 ec22efcec54217cd5015de67c06217dc 307 PIRSF PIRSF004491 1 307 1.1E-94 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CWM22_RS09545 eac354219fd0958ab6952a726c46dc60 61 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 4 56 7.3E-14 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 CWM22_RS09545 eac354219fd0958ab6952a726c46dc60 61 SUPERFAMILY SSF54786 1 58 7.06E-13 T 28-03-2018 CWM22_RS09545 eac354219fd0958ab6952a726c46dc60 61 Gene3D G3DSA:3.30.920.30 1 59 1.8E-17 T 28-03-2018 CWM22_RS01760 3580dc8fde50647e74f453c82214ec75 341 SUPERFAMILY SSF51735 135 299 4.87E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS01760 3580dc8fde50647e74f453c82214ec75 341 Pfam PF00107 Zinc-binding dehydrogenase 173 298 1.6E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWM22_RS01760 3580dc8fde50647e74f453c82214ec75 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CWM22_RS01760 3580dc8fde50647e74f453c82214ec75 341 SMART SM00829 10 335 2.7E-8 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWM22_RS01760 3580dc8fde50647e74f453c82214ec75 341 Gene3D G3DSA:3.40.50.720 164 285 5.6E-24 T 28-03-2018 CWM22_RS01760 3580dc8fde50647e74f453c82214ec75 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 4.0E-30 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWM22_RS01760 3580dc8fde50647e74f453c82214ec75 341 SUPERFAMILY SSF50129 1 170 5.17E-48 T 28-03-2018 IPR011032 GroES-like CWM22_RS01760 3580dc8fde50647e74f453c82214ec75 341 Gene3D G3DSA:3.90.180.10 1 163 6.2E-53 T 28-03-2018 CWM22_RS01845 028ee8c85a5ec8b8fb3dd2ad9539bcc0 580 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS01845 028ee8c85a5ec8b8fb3dd2ad9539bcc0 580 SUPERFAMILY SSF52540 328 571 1.03E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01845 028ee8c85a5ec8b8fb3dd2ad9539bcc0 580 Gene3D G3DSA:3.40.50.300 324 576 2.9E-70 T 28-03-2018 CWM22_RS01845 028ee8c85a5ec8b8fb3dd2ad9539bcc0 580 Pfam PF00005 ABC transporter 351 498 7.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS01845 028ee8c85a5ec8b8fb3dd2ad9539bcc0 580 SMART SM00382 360 546 3.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS01845 028ee8c85a5ec8b8fb3dd2ad9539bcc0 580 Gene3D G3DSA:1.20.1560.10 1 323 4.6E-58 T 28-03-2018 CWM22_RS01845 028ee8c85a5ec8b8fb3dd2ad9539bcc0 580 Pfam PF00664 ABC transporter transmembrane region 19 291 5.3E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS01845 028ee8c85a5ec8b8fb3dd2ad9539bcc0 580 SUPERFAMILY SSF90123 5 316 1.57E-70 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS09920 7e1d0e7f8ffd6aa90e1d0e2fe57a9691 162 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 14 152 1.2E-27 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWM22_RS09920 7e1d0e7f8ffd6aa90e1d0e2fe57a9691 162 SMART SM00047 1 156 9.8E-45 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWM22_RS09920 7e1d0e7f8ffd6aa90e1d0e2fe57a9691 162 PRINTS PR01002 Flagellar protein FlgJ signature 3 26 1.5E-10 T 28-03-2018 CWM22_RS09920 7e1d0e7f8ffd6aa90e1d0e2fe57a9691 162 PRINTS PR01002 Flagellar protein FlgJ signature 27 45 1.5E-10 T 28-03-2018 CWM22_RS09920 7e1d0e7f8ffd6aa90e1d0e2fe57a9691 162 PRINTS PR01002 Flagellar protein FlgJ signature 133 151 1.5E-10 T 28-03-2018 CWM22_RS09920 7e1d0e7f8ffd6aa90e1d0e2fe57a9691 162 Gene3D G3DSA:1.10.530.10 1 155 7.4E-44 T 28-03-2018 CWM22_RS00370 94f3d0da84b397a3d2a6f27df20462e5 570 Pfam PF00664 ABC transporter transmembrane region 19 288 1.0E-30 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS00370 94f3d0da84b397a3d2a6f27df20462e5 570 SUPERFAMILY SSF52540 327 563 2.28E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00370 94f3d0da84b397a3d2a6f27df20462e5 570 Gene3D G3DSA:1.20.1560.10 2 324 8.2E-49 T 28-03-2018 CWM22_RS00370 94f3d0da84b397a3d2a6f27df20462e5 570 Gene3D G3DSA:3.40.50.300 327 563 2.0E-63 T 28-03-2018 CWM22_RS00370 94f3d0da84b397a3d2a6f27df20462e5 570 SUPERFAMILY SSF90123 3 317 9.29E-55 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS00370 94f3d0da84b397a3d2a6f27df20462e5 570 Pfam PF00005 ABC transporter 345 495 1.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS00370 94f3d0da84b397a3d2a6f27df20462e5 570 SMART SM00382 354 541 3.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 447 37.293 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 SUPERFAMILY SSF52374 2 314 4.02E-96 T 28-03-2018 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 SMART SM00840 344 406 1.1E-12 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 446 5.6E-164 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 SUPERFAMILY SSF47323 328 446 8.5E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 Gene3D G3DSA:3.40.50.620 1 307 1.2E-89 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 8.8E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 8.8E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 8.8E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 8.8E-29 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 Gene3D G3DSA:1.20.120.640 308 424 4.4E-11 T 28-03-2018 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 Pfam PF09190 DALR domain 344 396 4.0E-14 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CWM22_RS11665 d5f26f6e10356cb9a5ae4822e0b574b7 447 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 314 1.5E-131 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 320 334 6.7E-24 T 28-03-2018 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 517 536 6.7E-24 T 28-03-2018 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 540 552 6.7E-24 T 28-03-2018 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 464 474 6.7E-24 T 28-03-2018 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 169 183 6.7E-24 T 28-03-2018 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 Gene3D G3DSA:3.40.50.1000 444 583 5.5E-39 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 Pfam PF00702 haloacid dehalogenase-like hydrolase 317 531 6.3E-40 T 28-03-2018 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 322 328 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 Gene3D G3DSA:1.20.1110.10 5 340 2.3E-27 T 28-03-2018 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 SUPERFAMILY SSF56784 433 615 3.79E-49 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 SUPERFAMILY SSF56784 319 386 3.79E-49 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 68 618 3.6E-171 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 Pfam PF00122 E1-E2 ATPase 119 300 4.5E-40 T 28-03-2018 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 SUPERFAMILY SSF81653 123 219 9.68E-21 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 Gene3D G3DSA:3.40.1110.10 341 443 6.3E-18 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 PRINTS PR00941 Cadmium-transporting ATPase signature 185 201 3.7E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 PRINTS PR00941 Cadmium-transporting ATPase signature 48 60 3.7E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 PRINTS PR00941 Cadmium-transporting ATPase signature 31 48 3.7E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 PRINTS PR00941 Cadmium-transporting ATPase signature 103 123 3.7E-7 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 91 592 2.2E-76 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 SUPERFAMILY SSF81665 220 314 1.11E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 SUPERFAMILY SSF81665 70 122 1.11E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS01935 a87f0022260edb9fd8cc30ff7d82027a 622 SUPERFAMILY SSF81665 565 594 1.11E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS06685 9da14b12171e1a1af0adc2270c443095 83 Gene3D G3DSA:1.20.5.780 1 75 4.8E-6 T 28-03-2018 CWM22_RS13415 6fa20f34dd741660bee15b4242cb86f1 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.029 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS13415 6fa20f34dd741660bee15b4242cb86f1 159 SUPERFAMILY SSF75217 1 157 2.04E-58 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWM22_RS13415 6fa20f34dd741660bee15b4242cb86f1 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 3.2E-51 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS13415 6fa20f34dd741660bee15b4242cb86f1 159 Gene3D G3DSA:3.40.1280.10 1 159 2.5E-58 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWM22_RS13415 6fa20f34dd741660bee15b4242cb86f1 159 PIRSF PIRSF004505 1 159 5.4E-52 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS13415 6fa20f34dd741660bee15b4242cb86f1 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 3.4E-57 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS03965 2f3dd264d3f0e53e60ba21eb65540a15 470 SUPERFAMILY SSF52540 52 320 3.26E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03965 2f3dd264d3f0e53e60ba21eb65540a15 470 Pfam PF04851 Type III restriction enzyme, res subunit 3 74 6.4E-10 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS03965 2f3dd264d3f0e53e60ba21eb65540a15 470 Pfam PF04851 Type III restriction enzyme, res subunit 102 136 1.6E-7 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS03965 2f3dd264d3f0e53e60ba21eb65540a15 470 Pfam PF00271 Helicase conserved C-terminal domain 212 307 3.3E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS03965 2f3dd264d3f0e53e60ba21eb65540a15 470 Gene3D G3DSA:3.40.50.300 1 206 1.7E-21 T 28-03-2018 CWM22_RS03965 2f3dd264d3f0e53e60ba21eb65540a15 470 SMART SM00487 1 168 1.4E-10 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS03965 2f3dd264d3f0e53e60ba21eb65540a15 470 SMART SM00490 230 311 9.4E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS03965 2f3dd264d3f0e53e60ba21eb65540a15 470 Gene3D G3DSA:3.40.50.300 207 446 7.2E-24 T 28-03-2018 CWM22_RS12160 b27c323181b8ecc5bb819ff27d3ccadb 284 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 9 25 9.8E-9 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CWM22_RS12160 b27c323181b8ecc5bb819ff27d3ccadb 284 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 184 196 9.8E-9 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CWM22_RS12160 b27c323181b8ecc5bb819ff27d3ccadb 284 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 32 46 9.8E-9 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CWM22_RS12160 b27c323181b8ecc5bb819ff27d3ccadb 284 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 55 68 9.8E-9 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CWM22_RS12160 b27c323181b8ecc5bb819ff27d3ccadb 284 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 9 246 1.6E-19 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CWM22_RS12160 b27c323181b8ecc5bb819ff27d3ccadb 284 PIRSF PIRSF000398 1 273 8.3E-56 T 28-03-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 CWM22_RS12160 b27c323181b8ecc5bb819ff27d3ccadb 284 Gene3D G3DSA:3.40.50.150 2 275 2.7E-30 T 28-03-2018 CWM22_RS12160 b27c323181b8ecc5bb819ff27d3ccadb 284 SUPERFAMILY SSF53335 3 266 3.1E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS04245 992fa941c95858aca16352ffbedff040 179 Pfam PF01965 DJ-1/PfpI family 3 162 1.6E-42 T 28-03-2018 IPR002818 DJ-1/PfpI CWM22_RS04245 992fa941c95858aca16352ffbedff040 179 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 4 167 2.3E-52 T 28-03-2018 IPR006287 Protein DJ-1 CWM22_RS04245 992fa941c95858aca16352ffbedff040 179 Gene3D G3DSA:3.40.50.880 1 179 1.7E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS04245 992fa941c95858aca16352ffbedff040 179 SUPERFAMILY SSF52317 1 167 1.15E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS10245 8ae52ae8ed3f5f5be258554ddd1c8c73 274 SUPERFAMILY SSF52402 3 273 1.8E-84 T 28-03-2018 CWM22_RS10245 8ae52ae8ed3f5f5be258554ddd1c8c73 274 Pfam PF02540 NAD synthase 23 265 3.7E-65 T 28-03-2018 IPR022310 NAD/GMP synthase CWM22_RS10245 8ae52ae8ed3f5f5be258554ddd1c8c73 274 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 274 3.0E-70 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CWM22_RS10245 8ae52ae8ed3f5f5be258554ddd1c8c73 274 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 268 29.588 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CWM22_RS10245 8ae52ae8ed3f5f5be258554ddd1c8c73 274 Gene3D G3DSA:3.40.50.620 2 274 6.0E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS12045 bc8952c86a35e95fab4e7368f6650bcf 410 Gene3D G3DSA:1.20.5.170 210 259 0.059 T 28-03-2018 CWM22_RS12045 bc8952c86a35e95fab4e7368f6650bcf 410 Pfam PF13437 HlyD family secretion protein 265 371 1.8E-12 T 28-03-2018 CWM22_RS12045 bc8952c86a35e95fab4e7368f6650bcf 410 Gene3D G3DSA:2.40.50.100 260 355 0.24 T 28-03-2018 CWM22_RS12045 bc8952c86a35e95fab4e7368f6650bcf 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 16 36 8.9E-10 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CWM22_RS12045 bc8952c86a35e95fab4e7368f6650bcf 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 335 358 8.9E-10 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CWM22_RS12045 bc8952c86a35e95fab4e7368f6650bcf 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 311 335 8.9E-10 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CWM22_RS12045 bc8952c86a35e95fab4e7368f6650bcf 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 381 396 8.9E-10 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CWM22_RS12045 bc8952c86a35e95fab4e7368f6650bcf 410 Gene3D G3DSA:1.10.287.510 105 209 1.8E-7 T 28-03-2018 CWM22_RS12045 bc8952c86a35e95fab4e7368f6650bcf 410 Gene3D G3DSA:3.90.1170.30 4 67 6.3E-7 T 28-03-2018 CWM22_RS05380 517f16b7b860beb017cd7a3edef11e10 128 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 18 121 6.0E-19 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CWM22_RS05380 517f16b7b860beb017cd7a3edef11e10 128 Pfam PF03061 Thioesterase superfamily 40 114 1.0E-12 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CWM22_RS05380 517f16b7b860beb017cd7a3edef11e10 128 Gene3D G3DSA:3.10.129.10 6 127 6.0E-25 T 28-03-2018 CWM22_RS05380 517f16b7b860beb017cd7a3edef11e10 128 SUPERFAMILY SSF54637 9 122 1.73E-26 T 28-03-2018 IPR029069 HotDog domain CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 SMART SM00358 161 228 7.5E-19 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 Gene3D G3DSA:3.30.160.20 159 226 1.9E-20 T 28-03-2018 CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 Pfam PF00035 Double-stranded RNA binding motif 161 225 8.2E-16 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 SUPERFAMILY SSF69065 4 163 8.2E-52 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 225 3.2E-80 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 SMART SM00535 20 155 1.3E-60 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 SUPERFAMILY SSF54768 151 226 6.91E-22 T 28-03-2018 CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 Pfam PF14622 Ribonuclease-III-like 20 149 1.4E-36 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 ProSitePatterns PS00517 Ribonuclease III family signature. 44 52 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 Gene3D G3DSA:1.10.1520.10 5 153 8.9E-44 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWM22_RS08275 3061c3bd74fad00754c71dc8af99f836 228 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 224 31.034 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 Gene3D G3DSA:3.40.50.720 2 187 8.3E-63 T 28-03-2018 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 142 155 4.1E-42 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 166 194 4.1E-42 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 218 235 4.1E-42 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 327 353 4.1E-42 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 236 252 4.1E-42 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 Gene3D G3DSA:3.30.360.10 188 483 9.2E-113 T 28-03-2018 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 SUPERFAMILY SSF51735 3 189 2.76E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 9 186 4.8E-57 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 SUPERFAMILY SSF55347 176 486 1.08E-105 T 28-03-2018 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 189 480 6.9E-103 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 5 480 7.9E-171 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 176 182 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 PIRSF PIRSF000110 1 484 1.4E-178 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS08215 eb16f824b08cb9531e7d157d22ad8844 495 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 4 482 81.918 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWM22_RS06870 c0271cc9dbd00d42db18ec35cf3b2e91 143 SUPERFAMILY SSF55729 1 138 3.76E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS06870 c0271cc9dbd00d42db18ec35cf3b2e91 143 Gene3D G3DSA:3.40.630.30 1 142 1.5E-22 T 28-03-2018 CWM22_RS06870 c0271cc9dbd00d42db18ec35cf3b2e91 143 Pfam PF00583 Acetyltransferase (GNAT) family 26 130 3.6E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS10780 44b6a3db6ffa75c26047d05d07e595c6 320 SUPERFAMILY SSF161098 93 301 2.62E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS10780 44b6a3db6ffa75c26047d05d07e595c6 320 Gene3D G3DSA:1.10.3720.10 2 303 2.3E-40 T 28-03-2018 CWM22_RS10780 44b6a3db6ffa75c26047d05d07e595c6 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 314 5.9E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS06205 b1d5003f290e1e2f6e7f0f2dc30cd6b8 256 Gene3D G3DSA:1.10.10.10 1 60 2.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06205 b1d5003f290e1e2f6e7f0f2dc30cd6b8 256 Gene3D G3DSA:3.40.50.1360 73 241 2.9E-27 T 28-03-2018 CWM22_RS06205 b1d5003f290e1e2f6e7f0f2dc30cd6b8 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CWM22_RS06205 b1d5003f290e1e2f6e7f0f2dc30cd6b8 256 SMART SM01134 73 236 6.4E-46 T 28-03-2018 CWM22_RS06205 b1d5003f290e1e2f6e7f0f2dc30cd6b8 256 SUPERFAMILY SSF100950 74 238 2.62E-26 T 28-03-2018 CWM22_RS06205 b1d5003f290e1e2f6e7f0f2dc30cd6b8 256 Pfam PF00455 DeoR C terminal sensor domain 75 235 5.0E-42 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CWM22_RS06205 b1d5003f290e1e2f6e7f0f2dc30cd6b8 256 SUPERFAMILY SSF46785 4 58 2.08E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06205 b1d5003f290e1e2f6e7f0f2dc30cd6b8 256 SMART SM00420 6 58 6.4E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS06205 b1d5003f290e1e2f6e7f0f2dc30cd6b8 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 8.4E-11 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS04870 0585ec8446f9778b2f47789ca79a8432 205 SUPERFAMILY SSF52266 17 204 9.47E-35 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWM22_RS04870 0585ec8446f9778b2f47789ca79a8432 205 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 22 194 4.6E-23 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWM22_RS04870 0585ec8446f9778b2f47789ca79a8432 205 Gene3D G3DSA:3.40.50.1110 17 205 3.1E-33 T 28-03-2018 CWM22_RS03425 3c5af8f21d1745ed0ec4237640771ebc 185 Gene3D G3DSA:1.10.132.20 73 184 1.5E-38 T 28-03-2018 CWM22_RS03425 3c5af8f21d1745ed0ec4237640771ebc 185 Gene3D G3DSA:1.10.132.20 2 72 3.5E-10 T 28-03-2018 CWM22_RS03425 3c5af8f21d1745ed0ec4237640771ebc 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.1E-71 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CWM22_RS03425 3c5af8f21d1745ed0ec4237640771ebc 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.133 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CWM22_RS03425 3c5af8f21d1745ed0ec4237640771ebc 185 SUPERFAMILY SSF55194 4 184 7.06E-70 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CWM22_RS03425 3c5af8f21d1745ed0ec4237640771ebc 185 Pfam PF01765 Ribosome recycling factor 21 183 2.1E-64 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CWM22_RS07035 1cbe1f6b50c0fc365edcd82417d91c5c 327 SUPERFAMILY SSF51412 5 316 2.62E-92 T 28-03-2018 CWM22_RS07035 1cbe1f6b50c0fc365edcd82417d91c5c 327 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 7 325 3.3E-199 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CWM22_RS07035 1cbe1f6b50c0fc365edcd82417d91c5c 327 Gene3D G3DSA:3.20.20.70 3 326 1.3E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS07035 1cbe1f6b50c0fc365edcd82417d91c5c 327 SMART SM01240 6 327 1.9E-110 T 28-03-2018 CWM22_RS07035 1cbe1f6b50c0fc365edcd82417d91c5c 327 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 311 1.0E-69 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CWM22_RS07035 1cbe1f6b50c0fc365edcd82417d91c5c 327 PIRSF PIRSF036500 3 327 2.7E-192 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CWM22_RS07035 1cbe1f6b50c0fc365edcd82417d91c5c 327 Hamap MF_01511 GMP reductase [guaC]. 5 326 62.547 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CWM22_RS07035 1cbe1f6b50c0fc365edcd82417d91c5c 327 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 166 178 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CWM22_RS08490 1e2faa1202a275fc1085b16034331db7 293 Pfam PF06161 Protein of unknown function (DUF975) 1 275 2.0E-38 T 28-03-2018 IPR010380 Protein of unknown function DUF975 CWM22_RS09230 b5e9e7e11bfa403637dcec19179b6e3a 361 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 289 301 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CWM22_RS09230 b5e9e7e11bfa403637dcec19179b6e3a 361 SUPERFAMILY SSF53092 2 129 1.74E-24 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWM22_RS09230 b5e9e7e11bfa403637dcec19179b6e3a 361 Pfam PF00557 Metallopeptidase family M24 140 343 6.5E-60 T 28-03-2018 IPR000994 Peptidase M24 CWM22_RS09230 b5e9e7e11bfa403637dcec19179b6e3a 361 SUPERFAMILY SSF55920 132 358 1.31E-79 T 28-03-2018 IPR000994 Peptidase M24 CWM22_RS09230 b5e9e7e11bfa403637dcec19179b6e3a 361 Gene3D G3DSA:3.90.230.10 132 360 6.5E-76 T 28-03-2018 CWM22_RS09230 b5e9e7e11bfa403637dcec19179b6e3a 361 Gene3D G3DSA:3.40.350.10 1 131 5.4E-19 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWM22_RS09230 b5e9e7e11bfa403637dcec19179b6e3a 361 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 132 3.7E-18 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWM22_RS07775 1c8fa8e83acd2119dc1b59a3a3427d45 64 Gene3D G3DSA:3.30.70.20 1 14 0.016 T 28-03-2018 CWM22_RS07775 1c8fa8e83acd2119dc1b59a3a3427d45 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 8 62 6.2E-9 T 28-03-2018 CWM22_RS07775 1c8fa8e83acd2119dc1b59a3a3427d45 64 Gene3D G3DSA:3.30.70.20 15 64 1.1E-6 T 28-03-2018 CWM22_RS07775 1c8fa8e83acd2119dc1b59a3a3427d45 64 SUPERFAMILY SSF54862 2 62 1.26E-6 T 28-03-2018 CWM22_RS00940 a921853caa26ecd04f1246b96dc52b0e 418 Gene3D G3DSA:3.90.190.20 294 417 8.1E-13 T 28-03-2018 CWM22_RS00940 a921853caa26ecd04f1246b96dc52b0e 418 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 412 1.8E-106 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CWM22_RS00940 a921853caa26ecd04f1246b96dc52b0e 418 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 142 157 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CWM22_RS00940 a921853caa26ecd04f1246b96dc52b0e 418 Pfam PF08245 Mur ligase middle domain 46 267 1.4E-4 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS00940 a921853caa26ecd04f1246b96dc52b0e 418 SUPERFAMILY SSF53623 1 292 1.68E-76 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS00940 a921853caa26ecd04f1246b96dc52b0e 418 Gene3D G3DSA:3.40.1190.10 1 293 2.1E-68 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS00940 a921853caa26ecd04f1246b96dc52b0e 418 SUPERFAMILY SSF53244 294 413 3.11E-19 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS00940 a921853caa26ecd04f1246b96dc52b0e 418 PIRSF PIRSF001563 1 417 6.7E-112 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CWM22_RS11750 cd527cb6d8cf5c4489123dafbf63a792 149 Pfam PF13673 Acetyltransferase (GNAT) domain 47 136 1.8E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS11750 cd527cb6d8cf5c4489123dafbf63a792 149 Gene3D G3DSA:3.40.630.30 11 146 3.0E-12 T 28-03-2018 CWM22_RS11750 cd527cb6d8cf5c4489123dafbf63a792 149 SUPERFAMILY SSF55729 19 137 5.22E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 Gene3D G3DSA:3.40.366.10 1 141 9.1E-47 T 28-03-2018 CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 306 2.0E-52 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 SUPERFAMILY SSF55048 126 194 1.57E-16 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 SUPERFAMILY SSF52151 187 303 3.4E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 SUPERFAMILY SSF52151 4 120 3.4E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 Gene3D G3DSA:3.30.70.250 142 178 1.3E-18 T 28-03-2018 CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 Pfam PF00698 Acyl transferase domain 6 283 3.3E-38 T 28-03-2018 IPR014043 Acyl transferase CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 287 1.8E-104 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 Gene3D G3DSA:3.40.366.10 179 305 5.5E-26 T 28-03-2018 CWM22_RS10935 17481a9b30590f74f4ea98f66571ce57 306 PIRSF PIRSF000446 1 305 1.9E-104 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CWM22_RS10265 1208356e49f181adfabb6b7159548544 213 PIRSF PIRSF012565 1 213 1.1E-64 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CWM22_RS10265 1208356e49f181adfabb6b7159548544 213 Pfam PF06265 Protein of unknown function (DUF1027) 30 110 1.0E-32 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CWM22_RS05975 260fa89d06445a23e7c3caddb8852704 108 Gene3D G3DSA:3.90.80.10 2 106 1.2E-12 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CWM22_RS05975 260fa89d06445a23e7c3caddb8852704 108 Pfam PF00719 Inorganic pyrophosphatase 21 89 1.9E-6 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CWM22_RS05975 260fa89d06445a23e7c3caddb8852704 108 SUPERFAMILY SSF50324 2 101 9.03E-18 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CWM22_RS03375 9cb669ddf50a0dc65c25ca9dae455fce 128 SUPERFAMILY SSF54593 3 128 4.56E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS03375 9cb669ddf50a0dc65c25ca9dae455fce 128 Gene3D G3DSA:3.10.180.10 1 128 4.7E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS03375 9cb669ddf50a0dc65c25ca9dae455fce 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 126 2.8E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:3.90.1810.10 3210 3304 4.3E-6 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 1685 1718 97.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2985 3018 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2270 2303 180.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 1815 1848 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2920 2953 340.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2725 2758 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2790 2823 200.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2855 2888 340.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2010 2043 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2205 2238 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 1750 1783 280.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2335 2368 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2595 2628 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2465 2498 200.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2400 2433 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 SMART SM00028 2530 2563 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1312 1365 1.9E-5 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 15 47 4.1E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 3335 3368 2.8E-5 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 944 1017 2.1E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1824 1883 4.6E-6 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2279 2343 1.5E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2474 2538 3.5E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 506 578 3.0E-9 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2604 2668 1.2E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1629 1688 2.9E-9 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2344 2408 2.0E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1021 1093 1.2E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2929 2993 1.7E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1097 1167 1.2E-8 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2409 2473 1.7E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 868 941 2.0E-12 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2149 2208 6.4E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2864 2924 6.5E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2994 3062 3.8E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 3069 3126 1.6E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2019 2078 5.5E-6 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1694 1754 1.7E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1434 1497 6.5E-6 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2214 2278 6.3E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1564 1624 1.1E-7 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1954 2013 9.0E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2084 2144 2.4E-8 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1173 1247 3.0E-6 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2539 2603 1.2E-9 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2799 2859 7.0E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1759 1818 1.5E-9 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1304 1364 2.0E-5 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 1889 1949 4.4E-8 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2669 2733 1.7E-9 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 430 499 9.1E-7 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF07564 Domain of Unknown Function (DUF1542) 2734 2798 3.2E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1633 1689 1.3E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1167 1240 0.088 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF00746 LPXTG cell wall anchor motif 3329 3368 2.2E-7 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2803 2857 1.3E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 798 842 0.013 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1892 1954 5.0E-4 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2607 2664 7.0E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2152 2209 9.0E-8 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1025 1082 2.7E-6 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2217 2273 2.0E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1372 1428 1.4E-4 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2672 2729 1.6E-6 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1567 1629 6.4E-4 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2997 3071 4.9E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1101 1158 0.0012 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1827 1885 5.9E-4 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1762 1819 7.7E-6 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2932 2989 3.9E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2022 2080 2.8E-4 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2737 2793 2.1E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2542 2599 1.6E-6 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1437 1494 0.0047 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 3073 3125 7.1E-9 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2282 2339 4.8E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1502 1561 0.0067 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2412 2469 2.8E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2347 2404 5.6E-6 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1957 2014 6.3E-6 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2867 2923 2.7E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2477 2534 8.6E-7 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 2087 2149 5.0E-4 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Gene3D G3DSA:1.20.5.420 1697 1753 2.1E-6 T 28-03-2018 CWM22_RS04710 762ca571c8db496130c2f63132b432c2 3372 Pfam PF04650 YSIRK type signal peptide 15 38 5.5E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 Gene3D G3DSA:3.20.14.10 345 593 1.7E-107 T 28-03-2018 CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 SUPERFAMILY SSF53743 3 359 6.02E-133 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 Gene3D G3DSA:3.40.50.1070 3 173 1.3E-59 T 28-03-2018 CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 Gene3D G3DSA:3.40.275.10 175 343 4.9E-59 T 28-03-2018 CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 Pfam PF02952 L-fucose isomerase, C-terminal domain 394 556 1.1E-48 T 28-03-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 Pfam PF07881 L-fucose isomerase, first N-terminal domain 4 172 6.1E-75 T 28-03-2018 IPR012888 L-fucose isomerase, N-terminal-1 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 SUPERFAMILY SSF50443 360 594 1.2E-112 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 Pfam PF07882 L-fucose isomerase, second N-terminal domain 173 358 2.1E-84 T 28-03-2018 IPR012889 L-fucose isomerase, N-terminal-2 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 Hamap MF_01254 L-fucose isomerase [fucI]. 1 595 67.446 T 28-03-2018 IPR005763 L-fucose isomerase GO:0005737|GO:0008736|GO:0019317|GO:0030145 KEGG: 00051+5.3.1.25 CWM22_RS06215 08099aa5bc2116d50e07f3733b69928c 595 TIGRFAM TIGR01089 fucI: L-fucose isomerase 4 593 1.4E-267 T 28-03-2018 IPR005763 L-fucose isomerase GO:0005737|GO:0008736|GO:0019317|GO:0030145 KEGG: 00051+5.3.1.25 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 6 45 1.6E-7 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Pfam PF07501 G5 domain 1030 1103 9.4E-5 T 28-03-2018 IPR011098 G5 domain CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Pfam PF07501 G5 domain 879 951 6.6E-9 T 28-03-2018 IPR011098 G5 domain CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Pfam PF07501 G5 domain 343 412 3.1E-8 T 28-03-2018 IPR011098 G5 domain CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Pfam PF07501 G5 domain 954 1024 3.7E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Pfam PF07580 M26 IgA1-specific Metallo-endopeptidase C-terminal region 1973 2712 1.1E-155 T 28-03-2018 IPR011505 Peptidase M26, C-terminal domain GO:0004222|GO:0005576|GO:0005618|GO:0008270 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Pfam PF05342 M26 IgA1-specific Metallo-endopeptidase N-terminal region 1413 1660 1.2E-54 T 28-03-2018 IPR008006 Peptidase M26, N-terminal domain GO:0004222|GO:0008270|GO:0016021 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Gene3D G3DSA:2.20.230.10 340 418 1.3E-11 T 28-03-2018 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Gene3D G3DSA:2.20.230.10 1026 1105 1.4E-7 T 28-03-2018 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Gene3D G3DSA:2.20.230.10 950 1021 1.1E-8 T 28-03-2018 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Gene3D G3DSA:2.20.230.10 1176 1260 6.6E-9 T 28-03-2018 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Gene3D G3DSA:2.20.230.10 1106 1175 7.7E-11 T 28-03-2018 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 Gene3D G3DSA:2.20.230.10 875 949 2.8E-11 T 28-03-2018 CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 SMART SM01208 1107 1178 0.0086 T 28-03-2018 IPR011098 G5 domain CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 SMART SM01208 1179 1252 0.15 T 28-03-2018 IPR011098 G5 domain CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 SMART SM01208 954 1025 0.0036 T 28-03-2018 IPR011098 G5 domain CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 SMART SM01208 336 413 4.1E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 SMART SM01208 874 952 1.8E-10 T 28-03-2018 IPR011098 G5 domain CWM22_RS03450 383ea93c1dbb8158b86d56496e29d77e 2716 SMART SM01208 1026 1104 0.0065 T 28-03-2018 IPR011098 G5 domain CWM22_RS02485 1a2cefb8015592ac56993df0e467fc63 312 Gene3D G3DSA:3.40.50.170 1 206 1.3E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWM22_RS02485 1a2cefb8015592ac56993df0e467fc63 312 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 304 5.8E-90 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CWM22_RS02485 1a2cefb8015592ac56993df0e467fc63 312 SUPERFAMILY SSF53328 3 203 1.15E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWM22_RS02485 1a2cefb8015592ac56993df0e467fc63 312 Pfam PF00551 Formyl transferase 5 179 1.2E-33 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWM22_RS02485 1a2cefb8015592ac56993df0e467fc63 312 Gene3D G3DSA:3.10.25.10 207 312 1.0E-29 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWM22_RS02485 1a2cefb8015592ac56993df0e467fc63 312 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 302 32.639 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CWM22_RS02485 1a2cefb8015592ac56993df0e467fc63 312 SUPERFAMILY SSF50486 205 303 1.24E-30 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CWM22_RS02485 1a2cefb8015592ac56993df0e467fc63 312 Pfam PF02911 Formyl transferase, C-terminal domain 204 299 4.5E-27 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWM22_RS02485 1a2cefb8015592ac56993df0e467fc63 312 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWM22_RS12215 fbc290ed36e4faaac7d27d98ad1df87b 331 Gene3D G3DSA:3.30.30.80 1 50 1.4E-18 T 28-03-2018 CWM22_RS12215 fbc290ed36e4faaac7d27d98ad1df87b 331 SUPERFAMILY SSF82708 269 324 4.32E-10 T 28-03-2018 IPR001374 R3H domain GO:0003676 CWM22_RS12215 fbc290ed36e4faaac7d27d98ad1df87b 331 SMART SM01245 2 53 7.5E-20 T 28-03-2018 IPR032782 Jag, N-terminal CWM22_RS12215 fbc290ed36e4faaac7d27d98ad1df87b 331 Gene3D G3DSA:3.30.300.20 180 257 1.2E-13 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS12215 fbc290ed36e4faaac7d27d98ad1df87b 331 SMART SM00393 248 327 1.0E-9 T 28-03-2018 IPR001374 R3H domain GO:0003676 CWM22_RS12215 fbc290ed36e4faaac7d27d98ad1df87b 331 Gene3D G3DSA:3.30.1370.50 259 328 1.2E-17 T 28-03-2018 IPR001374 R3H domain GO:0003676 CWM22_RS12215 fbc290ed36e4faaac7d27d98ad1df87b 331 Pfam PF13083 KH domain 186 255 1.5E-15 T 28-03-2018 CWM22_RS12215 fbc290ed36e4faaac7d27d98ad1df87b 331 Pfam PF01424 R3H domain 268 324 2.5E-17 T 28-03-2018 IPR001374 R3H domain GO:0003676 CWM22_RS12215 fbc290ed36e4faaac7d27d98ad1df87b 331 Pfam PF14804 Jag N-terminus 3 50 4.3E-17 T 28-03-2018 IPR032782 Jag, N-terminal CWM22_RS04785 2c4ec834ae73bfeee30c51d9e7d9d8cd 107 Gene3D G3DSA:3.30.300.130 8 106 1.1E-28 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CWM22_RS04785 2c4ec834ae73bfeee30c51d9e7d9d8cd 107 Pfam PF01883 Iron-sulfur cluster assembly protein 13 83 1.3E-22 T 28-03-2018 IPR002744 MIP18 family-like CWM22_RS04785 2c4ec834ae73bfeee30c51d9e7d9d8cd 107 SUPERFAMILY SSF117916 11 105 1.05E-30 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CWM22_RS07725 770626953cc167d6b626481d9e0df98d 388 PIRSF PIRSF001456 1 380 2.7E-121 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWM22_RS07725 770626953cc167d6b626481d9e0df98d 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWM22_RS07725 770626953cc167d6b626481d9e0df98d 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWM22_RS07725 770626953cc167d6b626481d9e0df98d 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWM22_RS07725 770626953cc167d6b626481d9e0df98d 388 SUPERFAMILY SSF103263 1 387 5.89E-144 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWM22_RS07725 770626953cc167d6b626481d9e0df98d 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 34.554 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWM22_RS07725 770626953cc167d6b626481d9e0df98d 388 Pfam PF01264 Chorismate synthase 1 363 2.3E-114 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWM22_RS07725 770626953cc167d6b626481d9e0df98d 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 368 2.2E-137 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWM22_RS07725 770626953cc167d6b626481d9e0df98d 388 Gene3D G3DSA:3.60.150.10 1 388 1.4E-131 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWM22_RS03420 5826053da621f05587ed67d33f463245 243 Gene3D G3DSA:3.40.1160.10 1 237 1.1E-41 T 28-03-2018 CWM22_RS03420 5826053da621f05587ed67d33f463245 243 PIRSF PIRSF005650 1 243 8.8E-93 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CWM22_RS03420 5826053da621f05587ed67d33f463245 243 SUPERFAMILY SSF53633 3 238 3.67E-71 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWM22_RS03420 5826053da621f05587ed67d33f463245 243 Pfam PF00696 Amino acid kinase family 7 216 1.8E-27 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWM22_RS03420 5826053da621f05587ed67d33f463245 243 Hamap MF_01220_B Uridylate kinase [pyrH]. 3 237 43.673 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CWM22_RS03420 5826053da621f05587ed67d33f463245 243 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 5 236 5.9E-97 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CWM22_RS08075 81b4ea780584b5e6b201a7a45e3ff8f7 347 Pfam PF01409 tRNA synthetases class II core domain (F) 98 347 1.9E-107 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CWM22_RS08075 81b4ea780584b5e6b201a7a45e3ff8f7 347 SUPERFAMILY SSF55681 98 347 8.82E-80 T 28-03-2018 CWM22_RS08075 81b4ea780584b5e6b201a7a45e3ff8f7 347 Gene3D G3DSA:3.30.930.10 11 347 8.6E-92 T 28-03-2018 CWM22_RS08075 81b4ea780584b5e6b201a7a45e3ff8f7 347 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 44 347 1.1E-106 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CWM22_RS08075 81b4ea780584b5e6b201a7a45e3ff8f7 347 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 12 347 45.576 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CWM22_RS08075 81b4ea780584b5e6b201a7a45e3ff8f7 347 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 27 93 7.5E-21 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CWM22_RS08075 81b4ea780584b5e6b201a7a45e3ff8f7 347 SUPERFAMILY SSF46589 23 105 5.13E-19 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWM22_RS03325 2693b61e3bc1b41b4590fbd6dcb36777 267 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 113 130 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CWM22_RS03325 2693b61e3bc1b41b4590fbd6dcb36777 267 Gene3D G3DSA:2.40.100.10 58 267 1.7E-68 T 28-03-2018 IPR029000 Cyclophilin-like domain CWM22_RS03325 2693b61e3bc1b41b4590fbd6dcb36777 267 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 92 107 6.6E-18 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWM22_RS03325 2693b61e3bc1b41b4590fbd6dcb36777 267 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 130 6.6E-18 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWM22_RS03325 2693b61e3bc1b41b4590fbd6dcb36777 267 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 169 184 6.6E-18 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWM22_RS03325 2693b61e3bc1b41b4590fbd6dcb36777 267 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 184 196 6.6E-18 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWM22_RS03325 2693b61e3bc1b41b4590fbd6dcb36777 267 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 79 260 4.4E-53 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWM22_RS03325 2693b61e3bc1b41b4590fbd6dcb36777 267 SUPERFAMILY SSF50891 79 265 4.82E-59 T 28-03-2018 IPR029000 Cyclophilin-like domain CWM22_RS05915 9240dbb11b7ea63ae2dd7c9f44520c81 478 Pfam PF07508 Recombinase 185 302 2.7E-25 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CWM22_RS05915 9240dbb11b7ea63ae2dd7c9f44520c81 478 SMART SM00857 4 160 2.1E-29 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS05915 9240dbb11b7ea63ae2dd7c9f44520c81 478 Pfam PF00239 Resolvase, N terminal domain 4 159 3.6E-21 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS05915 9240dbb11b7ea63ae2dd7c9f44520c81 478 SUPERFAMILY SSF53041 3 159 2.62E-25 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS05915 9240dbb11b7ea63ae2dd7c9f44520c81 478 Gene3D G3DSA:3.40.50.1390 1 167 5.3E-34 T 28-03-2018 CWM22_RS05915 9240dbb11b7ea63ae2dd7c9f44520c81 478 Pfam PF13408 Recombinase zinc beta ribbon domain 324 375 1.2E-7 T 28-03-2018 IPR025827 Recombinase zinc beta ribbon domain CWM22_RS01180 0a10099922be5c2b886252d50dbca08b 164 Gene3D G3DSA:1.10.10.10 2 54 1.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01180 0a10099922be5c2b886252d50dbca08b 164 Pfam PF04394 Protein of unknown function, DUF536 104 144 6.6E-17 T 28-03-2018 IPR007489 Domain of unknown function DUF536 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 Pfam PF03129 Anticodon binding domain 523 612 6.6E-18 T 28-03-2018 IPR004154 Anticodon-binding CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 Gene3D G3DSA:3.40.50.800 507 616 6.1E-24 T 28-03-2018 IPR004154 Anticodon-binding CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 Pfam PF04073 Aminoacyl-tRNA editing domain 295 414 3.4E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 94 494 3.4E-58 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 SUPERFAMILY SSF55826 256 424 3.27E-35 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 8.9E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 8.9E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 8.9E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 8.9E-15 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 SUPERFAMILY SSF55681 442 525 3.25E-83 T 28-03-2018 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 SUPERFAMILY SSF55681 9 228 3.25E-83 T 28-03-2018 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 247 612 1.4E-93 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 214 5.8E-97 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 Gene3D G3DSA:3.30.930.10 11 496 1.3E-83 T 28-03-2018 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 616 38.177 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CWM22_RS11865 d9d15b18b24a3bc1d820868809bb1ad4 616 SUPERFAMILY SSF52954 512 612 6.22E-27 T 28-03-2018 IPR004154 Anticodon-binding CWM22_RS11280 194b8605f343e20d7d94886d2e846374 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 156 21.406 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CWM22_RS11280 194b8605f343e20d7d94886d2e846374 156 SUPERFAMILY SSF74942 85 155 3.27E-19 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CWM22_RS11280 194b8605f343e20d7d94886d2e846374 156 Pfam PF17384 RimP C-terminal SH3 domain 94 155 6.4E-16 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CWM22_RS11280 194b8605f343e20d7d94886d2e846374 156 Pfam PF02576 RimP N-terminal domain 15 84 1.3E-20 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CWM22_RS11280 194b8605f343e20d7d94886d2e846374 156 Gene3D G3DSA:2.30.30.180 88 154 1.6E-17 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CWM22_RS11280 194b8605f343e20d7d94886d2e846374 156 SUPERFAMILY SSF75420 2 84 3.79E-24 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CWM22_RS11280 194b8605f343e20d7d94886d2e846374 156 Gene3D G3DSA:3.30.300.70 1 81 9.1E-18 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CWM22_RS11540 766304b69db4d3166865f9fe2818e3ff 148 PIRSF PIRSF002181 1 147 1.1E-46 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWM22_RS11540 766304b69db4d3166865f9fe2818e3ff 148 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 144 1.0E-57 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11540 766304b69db4d3166865f9fe2818e3ff 148 Pfam PF00572 Ribosomal protein L13 16 140 1.5E-52 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWM22_RS11540 766304b69db4d3166865f9fe2818e3ff 148 Gene3D G3DSA:3.90.1180.10 1 147 1.7E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWM22_RS11540 766304b69db4d3166865f9fe2818e3ff 148 ProSitePatterns PS00783 Ribosomal protein L13 signature. 107 129 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CWM22_RS11540 766304b69db4d3166865f9fe2818e3ff 148 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 17 143 25.973 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWM22_RS11540 766304b69db4d3166865f9fe2818e3ff 148 SUPERFAMILY SSF52161 6 144 8.24E-56 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 ProSitePatterns PS01128 Shikimate kinase signature. 52 78 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 PRINTS PR01100 Shikimate kinase family signature 3 18 3.6E-17 T 28-03-2018 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 PRINTS PR01100 Shikimate kinase family signature 92 109 3.6E-17 T 28-03-2018 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 PRINTS PR01100 Shikimate kinase family signature 23 36 3.6E-17 T 28-03-2018 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 PRINTS PR01100 Shikimate kinase family signature 51 59 3.6E-17 T 28-03-2018 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 PRINTS PR01100 Shikimate kinase family signature 70 79 3.6E-17 T 28-03-2018 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 Gene3D G3DSA:3.40.50.300 1 15 0.24 T 28-03-2018 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 Hamap MF_00109 Shikimate kinase [aroK]. 1 161 23.348 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 SUPERFAMILY SSF52540 2 161 1.46E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 Pfam PF01202 Shikimate kinase 9 161 6.9E-40 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CWM22_RS07610 6823cc697a4cf751d58b88ab9b77fcd3 163 Gene3D G3DSA:3.40.50.300 16 163 7.4E-28 T 28-03-2018 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 Pfam PF05746 DALR anticodon binding domain 449 562 1.6E-31 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 SMART SM01016 1 83 7.8E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 Gene3D G3DSA:3.30.1360.70 2 104 6.4E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 Gene3D G3DSA:3.40.50.620 105 429 1.3E-63 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 Gene3D G3DSA:1.10.730.10 430 562 1.2E-44 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 SUPERFAMILY SSF47323 443 562 2.62E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 SUPERFAMILY SSF52374 107 443 1.15E-101 T 28-03-2018 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 SMART SM00836 449 562 3.7E-41 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 SUPERFAMILY SSF55190 1 104 9.42E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 Pfam PF00750 tRNA synthetases class I (R) 94 434 1.8E-99 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 562 27.185 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 113 128 2.5E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 128 144 2.5E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 152 165 2.5E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 296 317 2.5E-20 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 4 83 1.5E-16 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS13065 52082fa428ab36d1b4dd1c6630d15246 562 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 6 562 1.1E-156 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWM22_RS02210 00bc4b6a912e9ba95358e3710eef6841 493 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 6 489 1.1E-231 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02210 00bc4b6a912e9ba95358e3710eef6841 493 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 254 271 - T 28-03-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02210 00bc4b6a912e9ba95358e3710eef6841 493 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 18 226 8.7E-40 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CWM22_RS02210 00bc4b6a912e9ba95358e3710eef6841 493 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 242 435 4.4E-36 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CWM22_RS02210 00bc4b6a912e9ba95358e3710eef6841 493 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 493 279.421 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS02210 00bc4b6a912e9ba95358e3710eef6841 493 PIRSF PIRSF006005 1 492 4.5E-231 T 28-03-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CWM22_RS01690 627a417c9d6811dd4917da7fe673df76 366 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 146 208 3.1E-5 T 28-03-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain CWM22_RS01690 627a417c9d6811dd4917da7fe673df76 366 Gene3D G3DSA:3.40.50.300 42 320 2.3E-9 T 28-03-2018 CWM22_RS01690 627a417c9d6811dd4917da7fe673df76 366 SUPERFAMILY SSF52540 138 323 4.79E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07800 c21d8e6cfbe13684999f893654f549cf 238 SUPERFAMILY SSF53448 1 221 2.3E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07800 c21d8e6cfbe13684999f893654f549cf 238 Gene3D G3DSA:3.90.550.10 1 230 3.4E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07800 c21d8e6cfbe13684999f893654f549cf 238 Pfam PF00535 Glycosyl transferase family 2 6 168 3.7E-18 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS07145 c180deebedb2966b572fd15088822d77 80 Pfam PF13083 KH domain 6 74 3.5E-17 T 28-03-2018 CWM22_RS07145 c180deebedb2966b572fd15088822d77 80 SUPERFAMILY SSF54814 12 61 7.45E-5 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWM22_RS07145 c180deebedb2966b572fd15088822d77 80 Hamap MF_00088 UPF0109 protein . 4 77 15.941 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 CWM22_RS07145 c180deebedb2966b572fd15088822d77 80 Gene3D G3DSA:3.30.300.20 1 78 1.8E-12 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS08765 fa6797194ffb857337c57a9ba078666f 203 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 200 25.595 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CWM22_RS08765 fa6797194ffb857337c57a9ba078666f 203 Pfam PF02525 Flavodoxin-like fold 3 198 8.7E-35 T 28-03-2018 IPR003680 Flavodoxin-like fold CWM22_RS08765 fa6797194ffb857337c57a9ba078666f 203 Gene3D G3DSA:3.40.50.360 1 203 4.3E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS08765 fa6797194ffb857337c57a9ba078666f 203 SUPERFAMILY SSF52218 1 202 5.19E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 SUPERFAMILY SSF52172 3 127 2.13E-32 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 Pfam PF00072 Response regulator receiver domain 6 118 7.8E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 Gene3D G3DSA:3.40.50.2300 3 128 5.9E-33 T 28-03-2018 CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 SMART SM00448 4 117 2.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 SMART SM00421 145 202 1.7E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 2.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 2.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 2.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 SUPERFAMILY SSF46894 136 208 1.46E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 Gene3D G3DSA:1.10.10.10 129 212 4.6E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02515 8e565961ba2da876b9a61fbb91900039 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 3.2E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWM22_RS02735 486ce0442fd4922ecc589253dce78711 712 Gene3D G3DSA:3.30.565.10 571 711 3.4E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02735 486ce0442fd4922ecc589253dce78711 712 Gene3D G3DSA:3.30.565.10 2 238 1.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02735 486ce0442fd4922ecc589253dce78711 712 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 618 710 5.6E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02735 486ce0442fd4922ecc589253dce78711 712 Gene3D G3DSA:1.20.1000.10 239 519 1.7E-4 T 28-03-2018 CWM22_RS02735 486ce0442fd4922ecc589253dce78711 712 SUPERFAMILY SSF55874 578 709 3.41E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02735 486ce0442fd4922ecc589253dce78711 712 SUPERFAMILY SSF55874 6 129 1.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS02735 486ce0442fd4922ecc589253dce78711 712 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 151 4.4E-21 T 28-03-2018 CWM22_RS07555 8c258f02c714430823c1b1aa822ff415 205 Pfam PF16475 Domain of unknown function (DUF5052) 5 203 7.7E-76 T 28-03-2018 IPR032484 Protein of unknown function DUF5052 CWM22_RS12455 c0c1cf971c84cbc1e848a3bc40e42099 246 Pfam PF00149 Calcineurin-like phosphoesterase 5 192 8.0E-15 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWM22_RS12455 c0c1cf971c84cbc1e848a3bc40e42099 246 Gene3D G3DSA:3.60.21.10 1 242 4.6E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS12455 c0c1cf971c84cbc1e848a3bc40e42099 246 SUPERFAMILY SSF56300 4 221 3.04E-39 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS05660 6e7f28f3c68690a08a45aa957aa2c97d 264 SUPERFAMILY SSF56112 3 264 1.36E-61 T 28-03-2018 IPR011009 Protein kinase-like domain CWM22_RS05660 6e7f28f3c68690a08a45aa957aa2c97d 264 Gene3D G3DSA:3.30.200.20 3 91 4.6E-17 T 28-03-2018 CWM22_RS05660 6e7f28f3c68690a08a45aa957aa2c97d 264 Gene3D G3DSA:3.90.1200.10 92 264 1.5E-25 T 28-03-2018 CWM22_RS05660 6e7f28f3c68690a08a45aa957aa2c97d 264 Pfam PF01636 Phosphotransferase enzyme family 52 256 3.0E-26 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CWM22_RS05660 6e7f28f3c68690a08a45aa957aa2c97d 264 PIRSF PIRSF000706 1 264 1.1E-92 T 28-03-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 CWM22_RS00375 8a03ab50797f3b906bfe90a0731782fe 422 SUPERFAMILY SSF46955 1 106 3.66E-21 T 28-03-2018 IPR009061 Putative DNA-binding domain CWM22_RS00375 8a03ab50797f3b906bfe90a0731782fe 422 Gene3D G3DSA:1.10.1660.10 1 56 1.1E-14 T 28-03-2018 CWM22_RS00375 8a03ab50797f3b906bfe90a0731782fe 422 Gene3D G3DSA:1.10.1660.10 57 137 4.0E-7 T 28-03-2018 CWM22_RS00375 8a03ab50797f3b906bfe90a0731782fe 422 Pfam PF13411 MerR HTH family regulatory protein 1 67 3.4E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS00375 8a03ab50797f3b906bfe90a0731782fe 422 SMART SM00422 1 70 1.3E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS11390 61b94ba6afb30066c97f26cc6a64bf45 407 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 403 3.9E-182 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWM22_RS11390 61b94ba6afb30066c97f26cc6a64bf45 407 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 213 232 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CWM22_RS11390 61b94ba6afb30066c97f26cc6a64bf45 407 Gene3D G3DSA:3.90.1150.10 279 399 1.2E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS11390 61b94ba6afb30066c97f26cc6a64bf45 407 SUPERFAMILY SSF53383 2 399 3.76E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS11390 61b94ba6afb30066c97f26cc6a64bf45 407 Pfam PF00266 Aminotransferase class-V 23 392 1.9E-153 T 28-03-2018 IPR000192 Aminotransferase class V domain CWM22_RS11390 61b94ba6afb30066c97f26cc6a64bf45 407 Gene3D G3DSA:3.40.640.10 31 278 5.9E-65 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS11390 61b94ba6afb30066c97f26cc6a64bf45 407 PIRSF PIRSF005572 20 404 1.2E-50 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWM22_RS05925 a7a82a86b0205be208a378fdbd187cbc 269 Gene3D G3DSA:3.40.190.10 166 269 7.2E-10 T 28-03-2018 CWM22_RS05925 a7a82a86b0205be208a378fdbd187cbc 269 SMART SM00079 39 264 1.2E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CWM22_RS05925 a7a82a86b0205be208a378fdbd187cbc 269 SUPERFAMILY SSF53850 1 258 3.46E-61 T 28-03-2018 CWM22_RS05925 a7a82a86b0205be208a378fdbd187cbc 269 Gene3D G3DSA:3.40.190.10 4 165 3.8E-36 T 28-03-2018 CWM22_RS05925 a7a82a86b0205be208a378fdbd187cbc 269 SMART SM00062 39 261 2.4E-42 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS05925 a7a82a86b0205be208a378fdbd187cbc 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 258 1.2E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS11075 add39b168681f93e00466dbf4b696302 164 Pfam PF00436 Single-strand binding protein family 2 103 5.0E-36 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWM22_RS11075 add39b168681f93e00466dbf4b696302 164 Gene3D G3DSA:2.40.50.140 1 111 2.6E-40 T 28-03-2018 CWM22_RS11075 add39b168681f93e00466dbf4b696302 164 SUPERFAMILY SSF50249 1 164 1.13E-53 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS11075 add39b168681f93e00466dbf4b696302 164 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 164 8.2E-47 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWM22_RS11075 add39b168681f93e00466dbf4b696302 164 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 35.978 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWM22_RS11075 add39b168681f93e00466dbf4b696302 164 PIRSF PIRSF002070 1 148 1.3E-38 T 28-03-2018 CWM22_RS12905 88a4af5acd1b449547709d684d0272f5 413 Pfam PF01381 Helix-turn-helix 12 61 3.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12905 88a4af5acd1b449547709d684d0272f5 413 Gene3D G3DSA:1.10.260.40 7 227 9.8E-10 T 28-03-2018 CWM22_RS12905 88a4af5acd1b449547709d684d0272f5 413 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 368 376 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CWM22_RS12905 88a4af5acd1b449547709d684d0272f5 413 SMART SM00530 11 67 1.0E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12905 88a4af5acd1b449547709d684d0272f5 413 SUPERFAMILY SSF47413 8 61 2.2E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS12905 88a4af5acd1b449547709d684d0272f5 413 Pfam PF02486 Replication initiation factor 175 384 3.2E-46 T 28-03-2018 IPR003491 Replication initiation factor GO:0003677|GO:0003916|GO:0006270 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Gene3D G3DSA:3.30.54.20 146 186 2.8E-19 T 28-03-2018 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 641 34.569 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Gene3D G3DSA:3.40.50.800 538 649 3.1E-28 T 28-03-2018 IPR004154 Anticodon-binding CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 637 3.1E-229 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 325 535 6.5E-35 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 SUPERFAMILY SSF55186 63 240 8.89E-62 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 SMART SM00863 169 218 1.9E-22 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Pfam PF03129 Anticodon binding domain 547 636 1.3E-22 T 28-03-2018 IPR004154 Anticodon-binding CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Gene3D G3DSA:3.30.980.10 65 145 7.7E-23 T 28-03-2018 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Gene3D G3DSA:3.10.20.30 1 63 4.9E-20 T 28-03-2018 IPR012675 Beta-grasp domain CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 2.3E-14 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Pfam PF02824 TGS domain 3 61 7.6E-12 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 498 1.1E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 540 552 1.1E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 1.1E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 1.1E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 513 526 1.1E-46 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 SUPERFAMILY SSF55681 242 532 5.18E-98 T 28-03-2018 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 SUPERFAMILY SSF81271 3 61 1.63E-16 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 SUPERFAMILY SSF52954 535 639 5.13E-32 T 28-03-2018 IPR004154 Anticodon-binding CWM22_RS08950 918b3ba261a0bb814063499d7c592aab 650 Gene3D G3DSA:3.30.930.10 220 537 1.3E-109 T 28-03-2018 CWM22_RS00565 97192a567dfb3dea33d26359486e4826 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00565 97192a567dfb3dea33d26359486e4826 132 Gene3D G3DSA:3.30.1370.30 1 67 2.5E-27 T 28-03-2018 CWM22_RS00565 97192a567dfb3dea33d26359486e4826 132 Gene3D G3DSA:3.30.1490.10 69 130 3.1E-23 T 28-03-2018 CWM22_RS00565 97192a567dfb3dea33d26359486e4826 132 SUPERFAMILY SSF56047 2 132 8.37E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00565 97192a567dfb3dea33d26359486e4826 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.868 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00565 97192a567dfb3dea33d26359486e4826 132 Pfam PF00410 Ribosomal protein S8 5 132 4.1E-53 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS11910 570128a409990c20b340a3f3bb686d32 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 38 2.2E-9 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWM22_RS11910 570128a409990c20b340a3f3bb686d32 162 SUPERFAMILY SSF52374 5 147 2.0E-17 T 28-03-2018 CWM22_RS11910 570128a409990c20b340a3f3bb686d32 162 Gene3D G3DSA:3.40.50.620 2 158 6.8E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS11715 cb993d952f7b6d31084ef2f27ab9e14b 72 SMART SM00530 5 60 2.0E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS11715 cb993d952f7b6d31084ef2f27ab9e14b 72 SUPERFAMILY SSF47413 5 67 1.13E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS11715 cb993d952f7b6d31084ef2f27ab9e14b 72 Gene3D G3DSA:3.30.1190.10 25 72 4.1E-11 T 28-03-2018 CWM22_RS11715 cb993d952f7b6d31084ef2f27ab9e14b 72 Gene3D G3DSA:1.10.10.10 3 24 2.7E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS11715 cb993d952f7b6d31084ef2f27ab9e14b 72 Pfam PF01381 Helix-turn-helix 6 60 4.0E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS02495 72171a7931f03f1b4facffdee75c28cc 245 Pfam PF13672 Protein phosphatase 2C 12 202 6.5E-16 T 28-03-2018 CWM22_RS02495 72171a7931f03f1b4facffdee75c28cc 245 SUPERFAMILY SSF81606 1 240 8.11E-58 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWM22_RS02495 72171a7931f03f1b4facffdee75c28cc 245 Gene3D G3DSA:3.60.40.10 1 245 1.1E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWM22_RS02495 72171a7931f03f1b4facffdee75c28cc 245 SMART SM00331 7 240 3.5E-35 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWM22_RS02495 72171a7931f03f1b4facffdee75c28cc 245 SMART SM00332 1 238 7.2E-12 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWM22_RS12490 2bff18b80d9fce1dfa44aa0db5a24024 562 Gene3D G3DSA:1.10.1790.10 301 413 1.4E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12490 2bff18b80d9fce1dfa44aa0db5a24024 562 Gene3D G3DSA:1.10.1790.10 196 300 1.1E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12490 2bff18b80d9fce1dfa44aa0db5a24024 562 Gene3D G3DSA:3.40.50.2300 419 508 3.1E-11 T 28-03-2018 CWM22_RS12490 2bff18b80d9fce1dfa44aa0db5a24024 562 Pfam PF00874 PRD domain 212 297 5.7E-5 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12490 2bff18b80d9fce1dfa44aa0db5a24024 562 Pfam PF00874 PRD domain 321 408 2.0E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12490 2bff18b80d9fce1dfa44aa0db5a24024 562 SUPERFAMILY SSF63520 310 410 5.75E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS12490 2bff18b80d9fce1dfa44aa0db5a24024 562 Gene3D G3DSA:1.10.10.10 86 157 5.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12490 2bff18b80d9fce1dfa44aa0db5a24024 562 Gene3D G3DSA:1.10.10.10 8 68 0.078 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10410 128f6776450fdc50252a501305607d4c 264 Gene3D G3DSA:3.40.50.1860 2 113 2.1E-27 T 28-03-2018 CWM22_RS10410 128f6776450fdc50252a501305607d4c 264 SUPERFAMILY SSF53681 109 262 9.32E-42 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS10410 128f6776450fdc50252a501305607d4c 264 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 253 5.5E-81 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS10410 128f6776450fdc50252a501305607d4c 264 SUPERFAMILY SSF53681 5 107 1.08E-35 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS10410 128f6776450fdc50252a501305607d4c 264 Hamap MF_00258 Glutamate racemase [murI]. 4 256 40.587 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS10410 128f6776450fdc50252a501305607d4c 264 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS10410 128f6776450fdc50252a501305607d4c 264 Gene3D G3DSA:3.40.50.1860 114 264 3.3E-41 T 28-03-2018 CWM22_RS10410 128f6776450fdc50252a501305607d4c 264 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 213 4.1E-39 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS04435 de33e6150e447f3a405f01e2c3be9383 559 Pfam PF01501 Glycosyl transferase family 8 2 236 1.3E-44 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CWM22_RS04435 de33e6150e447f3a405f01e2c3be9383 559 Pfam PF00535 Glycosyl transferase family 2 277 382 2.1E-6 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS04435 de33e6150e447f3a405f01e2c3be9383 559 SUPERFAMILY SSF53448 265 469 5.06E-13 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04435 de33e6150e447f3a405f01e2c3be9383 559 SUPERFAMILY SSF53448 1 253 1.29E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04435 de33e6150e447f3a405f01e2c3be9383 559 Gene3D G3DSA:3.90.550.10 264 532 5.4E-13 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04435 de33e6150e447f3a405f01e2c3be9383 559 Gene3D G3DSA:3.90.550.10 1 263 2.4E-49 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS12560 1b9564d0df140460e3d998ca33c18143 147 Pfam PF11687 Domain of unknown function (DUF3284) 1 121 8.7E-33 T 28-03-2018 IPR021701 Protein of unknown function DUF3284 CWM22_RS12560 1b9564d0df140460e3d998ca33c18143 147 Gene3D G3DSA:3.30.530.20 25 147 7.2E-5 T 28-03-2018 IPR023393 START-like domain CWM22_RS04415 fe8d434737264bb88857407faf484159 294 Pfam PF00535 Glycosyl transferase family 2 6 134 3.4E-38 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS04415 fe8d434737264bb88857407faf484159 294 Gene3D G3DSA:3.90.550.10 1 267 4.8E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04415 fe8d434737264bb88857407faf484159 294 SUPERFAMILY SSF53448 4 227 1.09E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS10370 d7325429d64deb9f649c6422f017d1b8 79 Pfam PF01809 Haemolytic domain 3 67 2.1E-27 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWM22_RS10370 d7325429d64deb9f649c6422f017d1b8 79 SMART SM01234 1 67 2.3E-44 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWM22_RS10370 d7325429d64deb9f649c6422f017d1b8 79 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 67 2.0E-23 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWM22_RS10370 d7325429d64deb9f649c6422f017d1b8 79 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 68 24.35 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWM22_RS10370 d7325429d64deb9f649c6422f017d1b8 79 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 74 2.8E-27 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWM22_RS02845 0d9cbaa6a7baa99dd557964b44cde710 146 SUPERFAMILY SSF55729 1 134 1.86E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS02845 0d9cbaa6a7baa99dd557964b44cde710 146 Pfam PF00583 Acetyltransferase (GNAT) family 29 129 3.2E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS02845 0d9cbaa6a7baa99dd557964b44cde710 146 Gene3D G3DSA:3.40.630.30 31 140 2.2E-15 T 28-03-2018 CWM22_RS02845 0d9cbaa6a7baa99dd557964b44cde710 146 Gene3D G3DSA:1.10.287.900 1 30 6.1E-11 T 28-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 CWM22_RS12310 4444dccc8d13b066874e4056dd7b8982 675 Pfam PF00746 LPXTG cell wall anchor motif 634 669 8.5E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS12310 4444dccc8d13b066874e4056dd7b8982 675 Pfam PF16555 Gram-positive pilin subunit D1, N-terminal 32 219 1.1E-33 T 28-03-2018 IPR032364 Gram-positive pilin subunit D1, N-terminal CWM22_RS12310 4444dccc8d13b066874e4056dd7b8982 675 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 640 670 2.3E-4 T 28-03-2018 CWM22_RS12310 4444dccc8d13b066874e4056dd7b8982 675 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 217 350 1.1E-22 T 28-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CWM22_RS12310 4444dccc8d13b066874e4056dd7b8982 675 Gene3D G3DSA:2.60.40.740 219 366 7.8E-22 T 28-03-2018 CWM22_RS12310 4444dccc8d13b066874e4056dd7b8982 675 Gene3D G3DSA:2.60.40.810 468 645 8.8E-18 T 28-03-2018 CWM22_RS12310 4444dccc8d13b066874e4056dd7b8982 675 Pfam PF16570 Gram-positive pilin backbone subunit 3, Cna-B-like domain 375 505 2.3E-20 T 28-03-2018 IPR032332 Gram-positive pilin backbone subunit 3, Cna-B-like domain CWM22_RS12310 4444dccc8d13b066874e4056dd7b8982 675 Pfam PF16569 Gram-positive pilin backbone subunit 2, Cna-B-like domain 237 353 7.5E-24 T 28-03-2018 IPR032334 Gram-positive pilin backbone subunit 2, Cna-B-like domain CWM22_RS12310 4444dccc8d13b066874e4056dd7b8982 675 Gene3D G3DSA:2.60.40.1140 367 462 6.0E-9 T 28-03-2018 CWM22_RS10690 ceea059741873fbb01c15a2ba0a982d9 221 Pfam PF02080 TrkA-C domain 150 219 2.3E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWM22_RS10690 ceea059741873fbb01c15a2ba0a982d9 221 SUPERFAMILY SSF116726 133 219 5.1E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWM22_RS10690 ceea059741873fbb01c15a2ba0a982d9 221 Gene3D G3DSA:3.30.70.1450 139 220 7.3E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWM22_RS10690 ceea059741873fbb01c15a2ba0a982d9 221 Pfam PF02254 TrkA-N domain 8 121 1.0E-25 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CWM22_RS10690 ceea059741873fbb01c15a2ba0a982d9 221 SUPERFAMILY SSF51735 6 135 2.36E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS10690 ceea059741873fbb01c15a2ba0a982d9 221 Gene3D G3DSA:3.40.50.720 3 138 5.6E-20 T 28-03-2018 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Pfam PF03147 Ferredoxin-fold anticodon binding domain 707 799 4.0E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 SUPERFAMILY SSF46955 409 479 4.03E-20 T 28-03-2018 IPR009061 Putative DNA-binding domain CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 SUPERFAMILY SSF56037 216 401 1.83E-66 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 SMART SM00896 707 799 3.8E-41 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 SMART SM00874 407 475 2.0E-26 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Gene3D G3DSA:3.30.70.380 703 799 6.6E-26 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Gene3D G3DSA:3.50.40.10 201 401 7.5E-66 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Pfam PF01588 Putative tRNA binding domain 45 148 1.4E-18 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 SUPERFAMILY SSF55681 471 693 2.34E-47 T 28-03-2018 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Gene3D G3DSA:3.30.56.10 407 479 7.2E-22 T 28-03-2018 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Pfam PF03484 tRNA synthetase B5 domain 410 475 1.3E-17 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 SUPERFAMILY SSF50249 37 194 1.57E-42 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Gene3D G3DSA:3.30.930.10 493 694 1.6E-32 T 28-03-2018 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Gene3D G3DSA:2.40.50.140 39 145 1.9E-37 T 28-03-2018 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 794 45.632 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 SMART SM00873 217 390 5.3E-84 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 SUPERFAMILY SSF54991 703 799 2.09E-29 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Pfam PF03483 B3/4 domain 220 390 8.0E-63 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 Gene3D G3DSA:3.30.56.10 146 188 4.6E-9 T 28-03-2018 CWM22_RS08065 ce3e270aebb60eb7933a174a213806fc 799 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 799 6.7E-255 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CWM22_RS05130 2a9aa9e3a5bb7ce01746f2b190ef16a1 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 296 7.4E-36 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWM22_RS05130 2a9aa9e3a5bb7ce01746f2b190ef16a1 317 Gene3D G3DSA:1.10.3470.10 1 303 2.0E-42 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS06320 c3217350c35c832d4d613acaf51096cd 605 SUPERFAMILY SSF52540 134 561 1.25E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06320 c3217350c35c832d4d613acaf51096cd 605 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 135 555 1.7E-66 T 28-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 CWM22_RS06320 c3217350c35c832d4d613acaf51096cd 605 Gene3D G3DSA:3.40.50.300 79 566 3.9E-37 T 28-03-2018 CWM22_RS12805 89333a1116bc52f094a2ef23fdf268d5 384 SUPERFAMILY SSF56349 60 363 3.53E-44 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS12805 89333a1116bc52f094a2ef23fdf268d5 384 Gene3D G3DSA:1.10.443.10 175 367 1.1E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS12805 89333a1116bc52f094a2ef23fdf268d5 384 Gene3D G3DSA:1.10.150.130 56 166 4.5E-5 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWM22_RS12805 89333a1116bc52f094a2ef23fdf268d5 384 Pfam PF00589 Phage integrase family 191 358 7.6E-18 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS07840 5decb2b4221cf106da7cbf4f43623644 404 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS07840 5decb2b4221cf106da7cbf4f43623644 404 Gene3D G3DSA:2.70.50.60 274 344 0.024 T 28-03-2018 CWM22_RS07840 5decb2b4221cf106da7cbf4f43623644 404 Gene3D G3DSA:3.40.50.300 4 273 2.1E-47 T 28-03-2018 CWM22_RS07840 5decb2b4221cf106da7cbf4f43623644 404 Pfam PF00005 ABC transporter 48 179 3.1E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS07840 5decb2b4221cf106da7cbf4f43623644 404 SUPERFAMILY SSF52540 32 244 5.44E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07840 5decb2b4221cf106da7cbf4f43623644 404 SMART SM00382 57 237 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS09470 42e8015eb0f271872163990e2d7c6f96 270 Gene3D G3DSA:3.40.50.10490 120 255 9.0E-20 T 28-03-2018 CWM22_RS09470 42e8015eb0f271872163990e2d7c6f96 270 SUPERFAMILY SSF53697 94 252 1.03E-27 T 28-03-2018 CWM22_RS09470 42e8015eb0f271872163990e2d7c6f96 270 Pfam PF01380 SIS domain 124 213 2.3E-11 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWM22_RS09470 42e8015eb0f271872163990e2d7c6f96 270 SUPERFAMILY SSF46689 7 78 1.97E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS09470 42e8015eb0f271872163990e2d7c6f96 270 Gene3D G3DSA:1.10.10.10 5 119 5.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS09470 42e8015eb0f271872163990e2d7c6f96 270 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 74 7.4E-10 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 Gene3D G3DSA:3.40.50.10490 67 208 3.3E-43 T 28-03-2018 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 1.6E-24 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 1.6E-24 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 1.6E-24 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 1.6E-24 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 1.6E-24 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 1.6E-24 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 Gene3D G3DSA:3.40.50.10490 1 66 4.1E-10 T 28-03-2018 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 409 426 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 Gene3D G3DSA:3.40.50.10490 209 435 2.7E-73 T 28-03-2018 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 436 24.405 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 SUPERFAMILY SSF53697 7 448 5.42E-135 T 28-03-2018 CWM22_RS12460 79367d69b4a81dfbf85520ac8ae35dfe 449 Pfam PF00342 Phosphoglucose isomerase 76 426 5.5E-22 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS13335 e2a47e17e91f7517c2a7e77b023241c6 278 Gene3D G3DSA:3.40.50.300 1 245 3.7E-69 T 28-03-2018 CWM22_RS13335 e2a47e17e91f7517c2a7e77b023241c6 278 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS13335 e2a47e17e91f7517c2a7e77b023241c6 278 SMART SM00382 32 217 1.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS13335 e2a47e17e91f7517c2a7e77b023241c6 278 SUPERFAMILY SSF52540 4 229 3.51E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13335 e2a47e17e91f7517c2a7e77b023241c6 278 Pfam PF00005 ABC transporter 23 169 1.8E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS13335 e2a47e17e91f7517c2a7e77b023241c6 278 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 5 272 9.3E-114 T 28-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 Pfam PF00746 LPXTG cell wall anchor motif 663 701 3.3E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 SUPERFAMILY SSF55816 367 581 1.57E-42 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 PRINTS PR01607 Apyrase family signature 68 86 1.1E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 PRINTS PR01607 Apyrase family signature 526 545 1.1E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 PRINTS PR01607 Apyrase family signature 428 451 1.1E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 PRINTS PR01607 Apyrase family signature 278 301 1.1E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 PIRSF PIRSF033095 47 701 0.0 T 28-03-2018 IPR014579 Predicted 5'-nucleotidase, SA0022 type CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 PIRSF PIRSF033095 7 54 1.6E-10 T 28-03-2018 IPR014579 Predicted 5'-nucleotidase, SA0022 type CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 Gene3D G3DSA:3.60.21.10 59 385 8.3E-60 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 Pfam PF02872 5'-nucleotidase, C-terminal domain 374 551 5.8E-33 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 SUPERFAMILY SSF56300 63 361 8.26E-61 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 ProSitePatterns PS00786 5'-nucleotidase signature 2. 140 151 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 669 699 5.2E-7 T 28-03-2018 CWM22_RS06000 eea5ad46563c37a619f4c6d80901a678 701 Gene3D G3DSA:3.90.780.10 386 595 3.0E-43 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWM22_RS08580 621999496672144651bce2b5486c823c 288 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 214 2.2E-21 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWM22_RS08580 621999496672144651bce2b5486c823c 288 Gene3D G3DSA:3.40.1010.10 13 123 3.3E-40 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWM22_RS08580 621999496672144651bce2b5486c823c 288 SUPERFAMILY SSF53790 13 231 1.01E-80 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWM22_RS08580 621999496672144651bce2b5486c823c 288 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS08580 621999496672144651bce2b5486c823c 288 PIRSF PIRSF005917 4 287 1.2E-96 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS08580 621999496672144651bce2b5486c823c 288 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 35.936 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS08580 621999496672144651bce2b5486c823c 288 Gene3D G3DSA:3.30.950.10 124 236 1.2E-37 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWM22_RS08580 621999496672144651bce2b5486c823c 288 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 16 285 4.8E-80 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 Pfam PF16570 Gram-positive pilin backbone subunit 3, Cna-B-like domain 372 502 7.2E-21 T 28-03-2018 IPR032332 Gram-positive pilin backbone subunit 3, Cna-B-like domain CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 Pfam PF00746 LPXTG cell wall anchor motif 633 668 8.0E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 SUPERFAMILY SSF49478 562 609 9.02E-5 T 28-03-2018 CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 Pfam PF16555 Gram-positive pilin subunit D1, N-terminal 29 216 1.5E-35 T 28-03-2018 IPR032364 Gram-positive pilin subunit D1, N-terminal CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 214 347 5.4E-23 T 28-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 Gene3D G3DSA:2.60.40.10 55 180 0.41 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 Gene3D G3DSA:2.60.40.1140 364 459 4.8E-9 T 28-03-2018 CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 638 667 5.5E-4 T 28-03-2018 CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 Pfam PF16569 Gram-positive pilin backbone subunit 2, Cna-B-like domain 234 350 5.6E-22 T 28-03-2018 IPR032334 Gram-positive pilin backbone subunit 2, Cna-B-like domain CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 Gene3D G3DSA:2.60.40.740 216 363 1.6E-22 T 28-03-2018 CWM22_RS08540 e3b45427ebbb0de1aba721020037399a 672 Gene3D G3DSA:2.60.40.810 465 644 2.9E-17 T 28-03-2018 CWM22_RS01645 b8536634cbb78d6d756aa2b599a51980 105 Gene3D G3DSA:1.20.58.80 4 102 7.1E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS01645 b8536634cbb78d6d756aa2b599a51980 105 TIGRFAM TIGR00823 EIIA-LAC: PTS system, lactose-specific IIa component 4 102 2.7E-45 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS01645 b8536634cbb78d6d756aa2b599a51980 105 SUPERFAMILY SSF46973 1 102 1.57E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS01645 b8536634cbb78d6d756aa2b599a51980 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 10 101 4.6E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS01645 b8536634cbb78d6d756aa2b599a51980 105 PIRSF PIRSF000699 1 105 5.2E-38 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS05425 48a576679a33459ff6ab78f9977ffdad 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS13030 48a576679a33459ff6ab78f9977ffdad 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS11990 48a576679a33459ff6ab78f9977ffdad 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS07675 48a576679a33459ff6ab78f9977ffdad 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS08245 48a576679a33459ff6ab78f9977ffdad 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS08865 48a576679a33459ff6ab78f9977ffdad 68 Pfam PF13007 Transposase C of IS166 homeodomain 25 64 3.0E-9 T 28-03-2018 IPR024463 Transposase TnpC, homeodomain CWM22_RS07065 6847f4e2456600a5dbf602eed54373c0 283 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 3 279 21.907 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CWM22_RS07065 6847f4e2456600a5dbf602eed54373c0 283 Gene3D G3DSA:3.40.1190.20 2 283 5.9E-37 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS07065 6847f4e2456600a5dbf602eed54373c0 283 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 8 274 9.6E-51 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CWM22_RS07065 6847f4e2456600a5dbf602eed54373c0 283 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 214 224 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CWM22_RS07065 6847f4e2456600a5dbf602eed54373c0 283 SUPERFAMILY SSF53613 4 275 1.28E-57 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS07065 6847f4e2456600a5dbf602eed54373c0 283 Pfam PF01256 Carbohydrate kinase 26 272 7.7E-61 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CWM22_RS00575 6963f87f9c5418c635a86c08fe77d6ee 118 SUPERFAMILY SSF53137 7 116 8.41E-53 T 28-03-2018 CWM22_RS00575 6963f87f9c5418c635a86c08fe77d6ee 118 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 118 5.6E-45 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00575 6963f87f9c5418c635a86c08fe77d6ee 118 Gene3D G3DSA:3.30.420.100 2 118 5.5E-41 T 28-03-2018 CWM22_RS00575 6963f87f9c5418c635a86c08fe77d6ee 118 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 118 3.2E-48 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00575 6963f87f9c5418c635a86c08fe77d6ee 118 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 118 29.123 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS13260 eb20a8e15e51687c72db7e54416d5913 153 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWM22_RS13260 eb20a8e15e51687c72db7e54416d5913 153 Gene3D G3DSA:3.90.79.10 1 149 5.0E-19 T 28-03-2018 CWM22_RS13260 eb20a8e15e51687c72db7e54416d5913 153 SUPERFAMILY SSF55811 8 131 5.15E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS13260 eb20a8e15e51687c72db7e54416d5913 153 Pfam PF00293 NUDIX domain 16 123 5.5E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWM22_RS13130 ccd372df104e5b3bd5f605e04a7a5958 504 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 3 494 6.6E-102 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CWM22_RS13130 ccd372df104e5b3bd5f605e04a7a5958 504 SUPERFAMILY SSF51445 4 495 5.06E-169 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS13130 ccd372df104e5b3bd5f605e04a7a5958 504 Pfam PF02446 4-alpha-glucanotransferase 10 474 1.1E-154 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CWM22_RS13130 ccd372df104e5b3bd5f605e04a7a5958 504 Gene3D G3DSA:3.20.20.80 1 496 7.4E-166 T 28-03-2018 CWM22_RS02655 4df5f3045264d4069b999ef8ef573e6e 236 SMART SM00866 86 228 9.2E-15 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS02655 4df5f3045264d4069b999ef8ef573e6e 236 Gene3D G3DSA:1.10.10.10 1 70 6.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02655 4df5f3045264d4069b999ef8ef573e6e 236 SMART SM00345 9 68 1.1E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS02655 4df5f3045264d4069b999ef8ef573e6e 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 1.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS02655 4df5f3045264d4069b999ef8ef573e6e 236 SUPERFAMILY SSF64288 56 234 3.45E-25 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS02655 4df5f3045264d4069b999ef8ef573e6e 236 SUPERFAMILY SSF46785 3 77 1.63E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02655 4df5f3045264d4069b999ef8ef573e6e 236 Gene3D G3DSA:3.40.1410.10 88 234 3.0E-24 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS02655 4df5f3045264d4069b999ef8ef573e6e 236 Pfam PF07702 UTRA domain 91 228 1.2E-21 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS04730 f19f1f89aec58b808c785872e923b1ab 347 Gene3D G3DSA:3.90.550.10 45 286 1.8E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04730 f19f1f89aec58b808c785872e923b1ab 347 SUPERFAMILY SSF53448 53 263 1.79E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04730 f19f1f89aec58b808c785872e923b1ab 347 Pfam PF00535 Glycosyl transferase family 2 56 180 3.5E-31 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 SMART SM00354 2 72 4.0E-35 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 Gene3D G3DSA:1.10.260.40 4 60 8.1E-21 T 28-03-2018 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 5.3E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 5.3E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 Gene3D G3DSA:3.40.50.2300 61 163 2.0E-21 T 28-03-2018 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 3.8E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 Pfam PF13377 Periplasmic binding protein-like domain 166 320 7.4E-23 T 28-03-2018 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 Gene3D G3DSA:3.40.50.2300 164 321 3.1E-33 T 28-03-2018 CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 SUPERFAMILY SSF53822 61 315 3.93E-62 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS11010 cecc5aebc3af46b7bf3fc31f9393a8e0 321 SUPERFAMILY SSF47413 3 57 2.33E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS07760 ad873a54380a2977c8317cfb9d64286b 168 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 3 164 8.4E-64 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWM22_RS07760 ad873a54380a2977c8317cfb9d64286b 168 ProSitePatterns PS00938 Initiation factor 3 signature. 54 67 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CWM22_RS07760 ad873a54380a2977c8317cfb9d64286b 168 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 79 163 6.0E-36 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CWM22_RS07760 ad873a54380a2977c8317cfb9d64286b 168 SUPERFAMILY SSF54364 2 74 5.89E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWM22_RS07760 ad873a54380a2977c8317cfb9d64286b 168 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 166 28.264 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWM22_RS07760 ad873a54380a2977c8317cfb9d64286b 168 Gene3D G3DSA:3.30.110.10 75 168 1.4E-32 T 28-03-2018 CWM22_RS07760 ad873a54380a2977c8317cfb9d64286b 168 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 3 72 2.1E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWM22_RS07760 ad873a54380a2977c8317cfb9d64286b 168 SUPERFAMILY SSF55200 78 166 6.41E-32 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CWM22_RS07760 ad873a54380a2977c8317cfb9d64286b 168 Gene3D G3DSA:3.10.20.80 1 74 3.8E-28 T 28-03-2018 CWM22_RS07755 15fdf0a2b305debfe67684ce4dbc9275 66 Pfam PF01632 Ribosomal protein L35 2 62 4.4E-21 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07755 15fdf0a2b305debfe67684ce4dbc9275 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS07755 15fdf0a2b305debfe67684ce4dbc9275 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.4E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWM22_RS07755 15fdf0a2b305debfe67684ce4dbc9275 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.4E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWM22_RS07755 15fdf0a2b305debfe67684ce4dbc9275 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.4E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWM22_RS07755 15fdf0a2b305debfe67684ce4dbc9275 66 SUPERFAMILY SSF143034 2 62 2.09E-19 T 28-03-2018 CWM22_RS07755 15fdf0a2b305debfe67684ce4dbc9275 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 6.3E-22 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWM22_RS07755 15fdf0a2b305debfe67684ce4dbc9275 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.578 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWM22_RS12745 8e78c49286a7fc78f93df2ac3d4f0a3c 147 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 1.8E-56 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CWM22_RS12745 8e78c49286a7fc78f93df2ac3d4f0a3c 147 SUPERFAMILY SSF69500 1 144 9.68E-57 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CWM22_RS12745 8e78c49286a7fc78f93df2ac3d4f0a3c 147 Gene3D G3DSA:3.50.80.10 1 144 4.4E-56 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CWM22_RS12745 8e78c49286a7fc78f93df2ac3d4f0a3c 147 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 144 34.523 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CWM22_RS12745 8e78c49286a7fc78f93df2ac3d4f0a3c 147 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 143 1.5E-54 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CWM22_RS06270 afd59034762b7a88c8cdac577e85a498 402 SUPERFAMILY SSF56349 83 363 1.5E-47 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS06270 afd59034762b7a88c8cdac577e85a498 402 Gene3D G3DSA:1.10.150.130 72 180 5.6E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWM22_RS06270 afd59034762b7a88c8cdac577e85a498 402 Gene3D G3DSA:1.10.443.10 181 364 3.0E-23 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS06270 afd59034762b7a88c8cdac577e85a498 402 Pfam PF13102 Phage integrase SAM-like domain 93 163 1.8E-5 T 28-03-2018 IPR025269 Phage integrase SAM-like domain CWM22_RS06270 afd59034762b7a88c8cdac577e85a498 402 Pfam PF00589 Phage integrase family 202 361 7.2E-16 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS08020 8716adf5f05cfdf86333bc3abcd86ad0 120 SMART SM00905 4 117 3.7E-49 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWM22_RS08020 8716adf5f05cfdf86333bc3abcd86ad0 120 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 1.7E-29 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWM22_RS08020 8716adf5f05cfdf86333bc3abcd86ad0 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 3.3E-37 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWM22_RS08020 8716adf5f05cfdf86333bc3abcd86ad0 120 SUPERFAMILY SSF55620 2 119 9.34E-39 T 28-03-2018 CWM22_RS08020 8716adf5f05cfdf86333bc3abcd86ad0 120 Pfam PF02152 Dihydroneopterin aldolase 4 116 1.2E-29 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWM22_RS08020 8716adf5f05cfdf86333bc3abcd86ad0 120 Gene3D G3DSA:3.30.1130.10 1 119 1.2E-31 T 28-03-2018 CWM22_RS05230 f2c499a126c786a0e189a823c2f1abe0 481 Pfam PF01943 Polysaccharide biosynthesis protein 17 271 5.4E-18 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CWM22_RS05230 f2c499a126c786a0e189a823c2f1abe0 481 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 336 442 4.5E-13 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CWM22_RS00220 2c85f4e5f6c94baddbce0527b48663bd 260 Pfam PF02565 Recombination protein O C terminal 84 237 1.1E-36 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CWM22_RS00220 2c85f4e5f6c94baddbce0527b48663bd 260 Pfam PF11967 Recombination protein O N terminal 1 78 5.0E-19 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CWM22_RS00220 2c85f4e5f6c94baddbce0527b48663bd 260 SUPERFAMILY SSF50249 2 78 1.88E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS00220 2c85f4e5f6c94baddbce0527b48663bd 260 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 243 1.4E-75 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CWM22_RS00220 2c85f4e5f6c94baddbce0527b48663bd 260 Gene3D G3DSA:2.40.50.140 2 81 3.8E-16 T 28-03-2018 CWM22_RS00220 2c85f4e5f6c94baddbce0527b48663bd 260 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 24.985 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CWM22_RS00220 2c85f4e5f6c94baddbce0527b48663bd 260 SUPERFAMILY SSF57863 80 232 3.4E-39 T 28-03-2018 CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 Gene3D G3DSA:1.10.8.60 139 226 7.0E-21 T 28-03-2018 CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 SMART SM00382 38 150 7.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 144 7.9E-16 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 Pfam PF16193 AAA C-terminal domain 173 250 3.6E-25 T 28-03-2018 IPR032423 AAA C-terminal domain CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 Gene3D G3DSA:3.40.50.300 2 138 4.0E-27 T 28-03-2018 CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 SUPERFAMILY SSF52540 4 226 1.09E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 SUPERFAMILY SSF48019 236 420 2.83E-64 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 Gene3D G3DSA:1.20.272.10 235 328 1.4E-32 T 28-03-2018 CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 Gene3D G3DSA:1.10.3710.10 331 426 1.0E-28 T 28-03-2018 CWM22_RS12790 a1d8c8e38d752b3242f0cac88484c771 426 Pfam PF12002 MgsA AAA+ ATPase C terminal 251 416 1.1E-58 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CWM22_RS11730 ad49efd6f3f7857e5cc5fc50dd9114e8 193 SUPERFAMILY SSF53271 1 187 1.24E-48 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS11730 ad49efd6f3f7857e5cc5fc50dd9114e8 193 Gene3D G3DSA:3.40.50.2020 3 188 1.0E-25 T 28-03-2018 CWM22_RS11730 ad49efd6f3f7857e5cc5fc50dd9114e8 193 Pfam PF00156 Phosphoribosyl transferase domain 37 156 1.1E-9 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWM22_RS11730 ad49efd6f3f7857e5cc5fc50dd9114e8 193 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 189 3.4E-78 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CWM22_RS11730 ad49efd6f3f7857e5cc5fc50dd9114e8 193 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 40.71 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CWM22_RS04920 9047cbc2f362bb3237effbff70ff85bf 141 Pfam PF01047 MarR family 28 86 2.2E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS04920 9047cbc2f362bb3237effbff70ff85bf 141 SUPERFAMILY SSF46785 7 133 2.63E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS04920 9047cbc2f362bb3237effbff70ff85bf 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 2.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS04920 9047cbc2f362bb3237effbff70ff85bf 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 2.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS04920 9047cbc2f362bb3237effbff70ff85bf 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 2.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS04920 9047cbc2f362bb3237effbff70ff85bf 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 2.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS04920 9047cbc2f362bb3237effbff70ff85bf 141 SMART SM00347 21 121 2.0E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS04920 9047cbc2f362bb3237effbff70ff85bf 141 ProSitePatterns PS01117 MarR-type HTH domain signature. 60 94 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CWM22_RS04920 9047cbc2f362bb3237effbff70ff85bf 141 Gene3D G3DSA:1.10.10.10 1 141 4.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS11425 088d543c7dcf22edfc0ab2fe0f6e099d 247 SMART SM00382 31 219 2.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11425 088d543c7dcf22edfc0ab2fe0f6e099d 247 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS11425 088d543c7dcf22edfc0ab2fe0f6e099d 247 PIRSF PIRSF039085 3 247 1.7E-109 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CWM22_RS11425 088d543c7dcf22edfc0ab2fe0f6e099d 247 Pfam PF00005 ABC transporter 22 171 2.4E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS11425 088d543c7dcf22edfc0ab2fe0f6e099d 247 Gene3D G3DSA:3.40.50.300 2 245 1.7E-75 T 28-03-2018 CWM22_RS11425 088d543c7dcf22edfc0ab2fe0f6e099d 247 SUPERFAMILY SSF52540 6 241 7.5E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05305 9e960e7b1de7a21c596e49bad68b8b0b 445 Pfam PF14264 Glucosyl transferase GtrII 8 276 2.4E-22 T 28-03-2018 IPR025686 Glucosyl transferase II CWM22_RS04755 84727265966ee9c4b526f2499bee2169 209 Pfam PF07314 Protein of unknown function (DUF1461) 7 180 1.6E-43 T 28-03-2018 IPR010178 Integral membrane protein 1906 CWM22_RS04755 84727265966ee9c4b526f2499bee2169 209 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 1 207 7.0E-53 T 28-03-2018 IPR010178 Integral membrane protein 1906 CWM22_RS08685 3ef02f4f96ea64e6283ba0aca4861a2a 482 SMART SM00642 6 423 7.5E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS08685 3ef02f4f96ea64e6283ba0aca4861a2a 482 TIGRFAM TIGR03852 sucrose_gtfA: sucrose phosphorylase 5 471 3.9E-266 T 28-03-2018 IPR022527 Sucrose phosphorylase GftA GO:0005985|GO:0009018 CWM22_RS08685 3ef02f4f96ea64e6283ba0aca4861a2a 482 Pfam PF00128 Alpha amylase, catalytic domain 36 254 2.9E-15 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS08685 3ef02f4f96ea64e6283ba0aca4861a2a 482 Gene3D G3DSA:3.20.20.80 13 432 3.0E-41 T 28-03-2018 CWM22_RS08685 3ef02f4f96ea64e6283ba0aca4861a2a 482 PIRSF PIRSF003059 1 481 1.6E-182 T 28-03-2018 IPR016377 Sucrose phosphorylase-related GO:0005985|GO:0009018 KEGG: 00500+2.4.1.7|MetaCyc: PWY-5384 CWM22_RS08685 3ef02f4f96ea64e6283ba0aca4861a2a 482 SUPERFAMILY SSF51445 4 426 2.07E-83 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 SUPERFAMILY SSF100950 75 235 2.66E-30 T 28-03-2018 CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 Gene3D G3DSA:1.10.10.10 1 67 6.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.4E-10 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.4E-10 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 1.3E-21 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 SMART SM01134 74 235 3.9E-60 T 28-03-2018 CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 SMART SM00420 6 58 2.8E-23 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 Pfam PF00455 DeoR C terminal sensor domain 76 233 2.4E-47 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 Gene3D G3DSA:3.40.50.1360 74 239 7.5E-32 T 28-03-2018 CWM22_RS01610 c0add8b78a1c9d366e0cbce3886f214a 255 SUPERFAMILY SSF46785 4 67 1.78E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08135 edd5922c071f696a45b15e917b01e215 279 SMART SM00892 100 277 5.6E-25 T 28-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 CWM22_RS08135 edd5922c071f696a45b15e917b01e215 279 ProSitePatterns PS01070 DNA/RNA non-specific endonucleases active site. 162 170 - T 28-03-2018 IPR018524 DNA/RNA non-specific endonuclease, active site GO:0003676|GO:0016787|GO:0046872 CWM22_RS08135 edd5922c071f696a45b15e917b01e215 279 Pfam PF01223 DNA/RNA non-specific endonuclease 81 236 1.7E-16 T 28-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 CWM22_RS07110 f4c0c63c8f048a454ccca6e2d3ec9f9e 384 SUPERFAMILY SSF52540 5 247 7.78E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07110 f4c0c63c8f048a454ccca6e2d3ec9f9e 384 Gene3D G3DSA:3.40.50.300 1 243 2.0E-79 T 28-03-2018 CWM22_RS07110 f4c0c63c8f048a454ccca6e2d3ec9f9e 384 Pfam PF00005 ABC transporter 23 165 1.7E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS07110 f4c0c63c8f048a454ccca6e2d3ec9f9e 384 SMART SM00382 32 215 5.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS07110 f4c0c63c8f048a454ccca6e2d3ec9f9e 384 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS07110 f4c0c63c8f048a454ccca6e2d3ec9f9e 384 Gene3D G3DSA:2.40.50.100 244 294 0.079 T 28-03-2018 CWM22_RS07110 f4c0c63c8f048a454ccca6e2d3ec9f9e 384 SUPERFAMILY SSF50331 240 345 7.94E-12 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CWM22_RS07110 f4c0c63c8f048a454ccca6e2d3ec9f9e 384 Pfam PF08402 TOBE domain 277 344 5.6E-5 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CWM22_RS07110 f4c0c63c8f048a454ccca6e2d3ec9f9e 384 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 38 291 5.1E-107 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CWM22_RS06640 966c3b0b00906fa58a39089ce11c4e6c 444 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 346 369 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CWM22_RS06640 966c3b0b00906fa58a39089ce11c4e6c 444 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 5 441 2.0E-207 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CWM22_RS06640 966c3b0b00906fa58a39089ce11c4e6c 444 SUPERFAMILY SSF51905 3 376 1.1E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS06640 966c3b0b00906fa58a39089ce11c4e6c 444 Pfam PF01134 Glucose inhibited division protein A 6 377 2.1E-114 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CWM22_RS06640 966c3b0b00906fa58a39089ce11c4e6c 444 Gene3D G3DSA:3.50.50.60 2 384 7.0E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS06640 966c3b0b00906fa58a39089ce11c4e6c 444 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 6 444 36.231 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CWM22_RS08565 1b31720cc1ad8cbb8e617b5344f80145 393 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 124 273 5.5E-43 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWM22_RS08565 1b31720cc1ad8cbb8e617b5344f80145 393 Gene3D G3DSA:3.40.50.720 28 98 4.4E-18 T 28-03-2018 CWM22_RS08565 1b31720cc1ad8cbb8e617b5344f80145 393 SUPERFAMILY SSF55021 309 389 1.49E-13 T 28-03-2018 CWM22_RS08565 1b31720cc1ad8cbb8e617b5344f80145 393 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 50 305 1.3E-17 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWM22_RS08565 1b31720cc1ad8cbb8e617b5344f80145 393 Gene3D G3DSA:3.30.70.260 307 389 1.9E-13 T 28-03-2018 CWM22_RS08565 1b31720cc1ad8cbb8e617b5344f80145 393 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 139 166 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CWM22_RS08565 1b31720cc1ad8cbb8e617b5344f80145 393 Gene3D G3DSA:3.40.50.720 99 275 1.1E-39 T 28-03-2018 CWM22_RS08565 1b31720cc1ad8cbb8e617b5344f80145 393 SUPERFAMILY SSF52283 28 107 9.45E-20 T 28-03-2018 CWM22_RS08565 1b31720cc1ad8cbb8e617b5344f80145 393 SUPERFAMILY SSF51735 87 274 1.01E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS10160 7e6813a599188316fba0309b5f9390e2 206 Gene3D G3DSA:3.40.30.10 1 206 2.0E-12 T 28-03-2018 CWM22_RS10160 7e6813a599188316fba0309b5f9390e2 206 SUPERFAMILY SSF52833 1 203 1.15E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 Gene3D G3DSA:3.30.300.20 17 106 3.5E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 Gene3D G3DSA:3.30.1140.32 107 206 2.7E-36 T 28-03-2018 CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 SUPERFAMILY SSF54821 106 205 4.58E-38 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.884 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 2.2E-39 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 5.5E-92 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 Pfam PF07650 KH domain 38 109 9.0E-21 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 SUPERFAMILY SSF54814 2 105 1.28E-37 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWM22_RS00525 0d3227acca8505550bbbfcba4d7700a7 217 SMART SM00322 59 124 2.1E-8 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Gene3D G3DSA:3.40.630.40 1055 1261 2.7E-60 T 28-03-2018 CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 SMART SM00646 1128 1258 1.5E-40 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Pfam PF08481 GBS Bsp-like repeat 303 392 5.3E-27 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Pfam PF08481 GBS Bsp-like repeat 961 1050 4.1E-26 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Pfam PF08481 GBS Bsp-like repeat 413 503 1.1E-22 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Pfam PF08481 GBS Bsp-like repeat 200 289 5.1E-27 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Pfam PF08481 GBS Bsp-like repeat 524 614 6.7E-27 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Pfam PF08481 GBS Bsp-like repeat 853 942 8.0E-26 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Pfam PF08481 GBS Bsp-like repeat 631 721 2.0E-27 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Pfam PF08481 GBS Bsp-like repeat 742 832 6.4E-24 T 28-03-2018 IPR013688 GBS Bsp-like CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Gene3D G3DSA:2.60.40.730 658 757 0.11 T 28-03-2018 CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Gene3D G3DSA:2.60.40.730 414 531 0.081 T 28-03-2018 CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Gene3D G3DSA:2.60.40.730 766 865 0.0016 T 28-03-2018 CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Gene3D G3DSA:2.60.40.730 317 413 0.061 T 28-03-2018 CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Gene3D G3DSA:2.60.40.730 549 641 0.27 T 28-03-2018 CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 1069 1258 7.2E-51 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWM22_RS09925 e7f48b5a49683736a8103481ec51d4b0 1267 SUPERFAMILY SSF53187 1067 1262 1.32E-52 T 28-03-2018 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 Gene3D G3DSA:3.40.1060.10 155 286 1.5E-41 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 Gene3D G3DSA:3.30.499.10 1 154 1.4E-36 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 Gene3D G3DSA:3.30.499.10 315 463 1.8E-46 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 ProSitePatterns PS01244 Aconitase family signature 2. 390 403 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 PRINTS PR00415 Aconitase family signature 390 403 1.6E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 PRINTS PR00415 Aconitase family signature 82 95 1.6E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 PRINTS PR00415 Aconitase family signature 209 222 1.6E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 PRINTS PR00415 Aconitase family signature 108 116 1.6E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 PRINTS PR00415 Aconitase family signature 195 208 1.6E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 PRINTS PR00415 Aconitase family signature 334 345 1.6E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 PRINTS PR00415 Aconitase family signature 284 298 1.6E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 PRINTS PR00415 Aconitase family signature 119 132 1.6E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 PRINTS PR00415 Aconitase family signature 133 148 1.6E-43 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 ProSitePatterns PS00450 Aconitase family signature 1. 330 346 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 457 54.877 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 455 1.6E-197 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 SUPERFAMILY SSF53732 3 459 4.97E-157 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11805 ce88222656b4388f39a69ee8bdb7b260 463 Pfam PF00330 Aconitase family (aconitate hydratase) 8 448 1.9E-141 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS03520 c4cc8242c66c3752052516cbb3ba90ec 419 Pfam PF00155 Aminotransferase class I and II 108 300 6.6E-15 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWM22_RS03520 c4cc8242c66c3752052516cbb3ba90ec 419 SUPERFAMILY SSF53383 83 403 1.75E-53 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS03520 c4cc8242c66c3752052516cbb3ba90ec 419 SMART SM00345 7 66 2.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS03520 c4cc8242c66c3752052516cbb3ba90ec 419 Gene3D G3DSA:1.10.10.10 1 67 1.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03520 c4cc8242c66c3752052516cbb3ba90ec 419 Gene3D G3DSA:3.90.1150.10 308 376 0.0011 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS03520 c4cc8242c66c3752052516cbb3ba90ec 419 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS03520 c4cc8242c66c3752052516cbb3ba90ec 419 Gene3D G3DSA:3.40.640.10 103 307 1.4E-22 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS03520 c4cc8242c66c3752052516cbb3ba90ec 419 SUPERFAMILY SSF46785 2 70 8.17E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02690 9eb0be1f12a746e06882ebce056d0ad7 84 SUPERFAMILY SSF140121 1 77 3.4E-41 T 28-03-2018 CWM22_RS02690 9eb0be1f12a746e06882ebce056d0ad7 84 Pfam PF08930 Domain of unknown function (DUF1912) 1 84 7.2E-49 T 28-03-2018 IPR015026 Protein of unknown function DUF1912 CWM22_RS02690 9eb0be1f12a746e06882ebce056d0ad7 84 Gene3D G3DSA:1.20.58.90 1 84 1.2E-48 T 28-03-2018 CWM22_RS11130 ed72f0a5785a3b5a350f108a0ecc0bc3 104 Gene3D G3DSA:3.40.50.2300 1 104 4.4E-21 T 28-03-2018 CWM22_RS11130 ed72f0a5785a3b5a350f108a0ecc0bc3 104 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 100 1.7E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS11130 ed72f0a5785a3b5a350f108a0ecc0bc3 104 SUPERFAMILY SSF52794 1 89 1.88E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS06755 a477eaa4d5a71c4cc49793579f1de244 279 Gene3D G3DSA:3.40.190.10 1 254 4.5E-6 T 28-03-2018 CWM22_RS11595 be385d6466ea6dc4d45f4462e0b7ffe7 285 Gene3D G3DSA:1.10.10.60 217 259 3.7E-6 T 28-03-2018 CWM22_RS11595 be385d6466ea6dc4d45f4462e0b7ffe7 285 Pfam PF13556 PucR C-terminal helix-turn-helix domain 234 279 1.4E-11 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CWM22_RS13330 c5129acb9d082809898387950cd97feb 280 SUPERFAMILY SSF52540 4 237 8.05E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13330 c5129acb9d082809898387950cd97feb 280 Pfam PF00005 ABC transporter 25 174 8.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS13330 c5129acb9d082809898387950cd97feb 280 SMART SM00382 32 222 1.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS13330 c5129acb9d082809898387950cd97feb 280 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 277 1.8E-118 T 28-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CWM22_RS13330 c5129acb9d082809898387950cd97feb 280 Gene3D G3DSA:3.40.50.300 2 245 4.3E-63 T 28-03-2018 CWM22_RS13330 c5129acb9d082809898387950cd97feb 280 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS09010 00df9917bcfb8f9109f7392775955ced 94 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 6 85 3.1E-9 T 28-03-2018 IPR001357 BRCT domain CWM22_RS09010 00df9917bcfb8f9109f7392775955ced 94 SUPERFAMILY SSF52113 5 92 2.13E-12 T 28-03-2018 IPR001357 BRCT domain CWM22_RS09010 00df9917bcfb8f9109f7392775955ced 94 Gene3D G3DSA:3.40.50.10190 4 93 4.9E-13 T 28-03-2018 IPR001357 BRCT domain CWM22_RS10070 13549f14bd6192569ca0b46cdfcc4a93 354 SUPERFAMILY SSF51679 21 342 3.27E-74 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWM22_RS10070 13549f14bd6192569ca0b46cdfcc4a93 354 Gene3D G3DSA:3.20.20.30 1 354 4.5E-65 T 28-03-2018 CWM22_RS10070 13549f14bd6192569ca0b46cdfcc4a93 354 Pfam PF00296 Luciferase-like monooxygenase 13 301 2.1E-40 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWM22_RS10070 13549f14bd6192569ca0b46cdfcc4a93 354 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 3 341 1.6E-157 T 28-03-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative CWM22_RS09915 136eeeedf9b4a72fbaa520162235bd46 429 Gene3D G3DSA:3.90.350.10 123 335 1.7E-24 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS09915 136eeeedf9b4a72fbaa520162235bd46 429 SUPERFAMILY SSF53098 98 392 6.37E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS09915 136eeeedf9b4a72fbaa520162235bd46 429 Pfam PF01609 Transposase DDE domain 100 351 1.7E-26 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS11305 2816505ee26e15a81c6bfc106f8835b0 244 SMART SM00382 26 211 5.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11305 2816505ee26e15a81c6bfc106f8835b0 244 Gene3D G3DSA:3.40.50.300 1 239 1.2E-57 T 28-03-2018 CWM22_RS11305 2816505ee26e15a81c6bfc106f8835b0 244 Pfam PF00005 ABC transporter 17 160 1.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS11305 2816505ee26e15a81c6bfc106f8835b0 244 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS11305 2816505ee26e15a81c6bfc106f8835b0 244 SUPERFAMILY SSF52540 1 225 6.21E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06260 1840f6825f6e12068b406ac9c51633ac 138 Gene3D G3DSA:1.10.10.10 73 138 1.0E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06260 1840f6825f6e12068b406ac9c51633ac 138 Pfam PF04545 Sigma-70, region 4 82 129 2.6E-8 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS06260 1840f6825f6e12068b406ac9c51633ac 138 SUPERFAMILY SSF88659 49 134 5.23E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS06260 1840f6825f6e12068b406ac9c51633ac 138 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 59 132 7.8E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 PRINTS PR00395 Ribosomal protein S2 signature 37 46 6.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 PRINTS PR00395 Ribosomal protein S2 signature 158 175 6.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 PRINTS PR00395 Ribosomal protein S2 signature 196 210 6.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 PRINTS PR00395 Ribosomal protein S2 signature 6 24 6.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 PRINTS PR00395 Ribosomal protein S2 signature 87 104 6.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 PRINTS PR00395 Ribosomal protein S2 signature 175 186 6.2E-42 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 SUPERFAMILY SSF52313 6 231 3.66E-96 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 Gene3D G3DSA:3.40.50.10490 5 256 5.2E-99 T 28-03-2018 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 42.9 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 6.1E-106 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11940 6c896812c9c7a7bdefd347d5a2d661d5 258 Pfam PF00318 Ribosomal protein S2 9 224 3.8E-97 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS02175 35b2bc09470796c0f9ef7b9b7d4f28aa 34 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 1 34 7.4E-9 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) CWM22_RS10790 3c870acb81292c37b0a5fe6e0663f0fe 749 SUPERFAMILY SSF51726 1 372 1.83E-95 T 28-03-2018 CWM22_RS10790 3c870acb81292c37b0a5fe6e0663f0fe 749 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 3 311 2.4E-113 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWM22_RS10790 3c870acb81292c37b0a5fe6e0663f0fe 749 SUPERFAMILY SSF51726 386 748 4.06E-106 T 28-03-2018 CWM22_RS10790 3c870acb81292c37b0a5fe6e0663f0fe 749 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 420 743 1.1E-135 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWM22_RS10790 3c870acb81292c37b0a5fe6e0663f0fe 749 Gene3D G3DSA:3.20.20.210 1 379 1.3E-119 T 28-03-2018 CWM22_RS10790 3c870acb81292c37b0a5fe6e0663f0fe 749 PIRSF PIRSF000382 1 749 1.5E-301 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWM22_RS10790 3c870acb81292c37b0a5fe6e0663f0fe 749 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 6 747 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWM22_RS10790 3c870acb81292c37b0a5fe6e0663f0fe 749 Gene3D G3DSA:3.20.20.210 380 749 1.1E-112 T 28-03-2018 CWM22_RS10790 3c870acb81292c37b0a5fe6e0663f0fe 749 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 1 748 33.661 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWM22_RS07890 93ec26247cf799507ee48ca28bc3bae9 348 Pfam PF16363 GDP-mannose 4,6 dehydratase 8 318 9.1E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS07890 93ec26247cf799507ee48ca28bc3bae9 348 Gene3D G3DSA:3.90.25.10 196 348 1.1E-42 T 28-03-2018 CWM22_RS07890 93ec26247cf799507ee48ca28bc3bae9 348 SUPERFAMILY SSF51735 5 336 2.9E-94 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS07890 93ec26247cf799507ee48ca28bc3bae9 348 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 7 330 3.9E-136 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CWM22_RS07890 93ec26247cf799507ee48ca28bc3bae9 348 Gene3D G3DSA:3.40.50.720 5 195 6.6E-37 T 28-03-2018 CWM22_RS02420 726aee4cce7b3e0f445fc8ba38c90dcc 728 Pfam PF00912 Transglycosylase 64 240 3.8E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWM22_RS02420 726aee4cce7b3e0f445fc8ba38c90dcc 728 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 74 637 1.6E-159 T 28-03-2018 CWM22_RS02420 726aee4cce7b3e0f445fc8ba38c90dcc 728 SUPERFAMILY SSF56601 277 658 9.33E-89 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS02420 726aee4cce7b3e0f445fc8ba38c90dcc 728 SUPERFAMILY SSF56601 222 244 9.33E-89 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS02420 726aee4cce7b3e0f445fc8ba38c90dcc 728 SUPERFAMILY SSF53955 54 268 2.0E-66 T 28-03-2018 IPR023346 Lysozyme-like domain CWM22_RS02420 726aee4cce7b3e0f445fc8ba38c90dcc 728 Gene3D G3DSA:1.10.3810.10 56 257 1.8E-71 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWM22_RS02420 726aee4cce7b3e0f445fc8ba38c90dcc 728 Gene3D G3DSA:3.40.710.10 268 660 1.8E-79 T 28-03-2018 CWM22_RS02420 726aee4cce7b3e0f445fc8ba38c90dcc 728 Pfam PF00905 Penicillin binding protein transpeptidase domain 335 597 8.9E-34 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWM22_RS08100 4a7d193870c5e0322d558156efce8e05 366 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 343 1.1E-135 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CWM22_RS08100 4a7d193870c5e0322d558156efce8e05 366 Gene3D G3DSA:3.20.20.150 1 366 2.9E-109 T 28-03-2018 CWM22_RS08100 4a7d193870c5e0322d558156efce8e05 366 PIRSF PIRSF016049 1 145 2.4E-46 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CWM22_RS08100 4a7d193870c5e0322d558156efce8e05 366 PIRSF PIRSF016049 143 350 9.0E-69 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CWM22_RS08100 4a7d193870c5e0322d558156efce8e05 366 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 366 162.342 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 CWM22_RS08100 4a7d193870c5e0322d558156efce8e05 366 SUPERFAMILY SSF51658 1 342 1.13E-79 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 SUPERFAMILY SSF47323 571 829 6.54E-66 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Gene3D G3DSA:1.10.730.10 518 747 2.9E-69 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Gene3D G3DSA:3.40.50.620 35 204 2.4E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Gene3D G3DSA:3.90.740.10 205 237 2.4E-6 T 28-03-2018 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 SUPERFAMILY SSF46589 814 878 1.36E-15 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Gene3D G3DSA:3.90.740.10 238 430 3.4E-63 T 28-03-2018 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Pfam PF08264 Anticodon-binding domain of tRNA 610 755 1.5E-39 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Hamap MF_02004 Valine--tRNA ligase [valS]. 5 879 15.693 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 SUPERFAMILY SSF52374 5 195 1.27E-140 T 28-03-2018 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 SUPERFAMILY SSF52374 343 570 1.27E-140 T 28-03-2018 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 879 1.3E-16 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 861 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 57 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Gene3D G3DSA:3.40.50.620 431 517 5.2E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 PRINTS PR00986 Valyl-tRNA synthetase signature 440 461 4.9E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 PRINTS PR00986 Valyl-tRNA synthetase signature 348 361 4.9E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 PRINTS PR00986 Valyl-tRNA synthetase signature 472 490 4.9E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 PRINTS PR00986 Valyl-tRNA synthetase signature 39 50 4.9E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 PRINTS PR00986 Valyl-tRNA synthetase signature 233 250 4.9E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 SUPERFAMILY SSF50677 193 344 3.92E-61 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 437 560 1.1E-55 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 429 1.1E-162 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS02715 b9543e774e33c07819d7de60ca1c07a7 883 Gene3D G3DSA:1.10.287.380 807 877 6.7E-23 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CWM22_RS04680 c884198889b947657e9dc8f31730bbd7 237 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 236 42.018 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CWM22_RS04680 c884198889b947657e9dc8f31730bbd7 237 SUPERFAMILY SSF53167 2 235 9.56E-85 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWM22_RS04680 c884198889b947657e9dc8f31730bbd7 237 Pfam PF01048 Phosphorylase superfamily 16 221 2.7E-41 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWM22_RS04680 c884198889b947657e9dc8f31730bbd7 237 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 233 1.1E-85 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CWM22_RS04680 c884198889b947657e9dc8f31730bbd7 237 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS04680 c884198889b947657e9dc8f31730bbd7 237 Gene3D G3DSA:3.40.50.1580 8 237 2.9E-55 T 28-03-2018 CWM22_RS01995 f7482c7b9bb29e629b595254f049bcab 209 SUPERFAMILY SSF51735 1 208 2.86E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS01995 f7482c7b9bb29e629b595254f049bcab 209 Gene3D G3DSA:3.40.50.720 1 209 1.5E-12 T 28-03-2018 CWM22_RS01995 f7482c7b9bb29e629b595254f049bcab 209 Pfam PF13460 NAD(P)H-binding 8 192 2.6E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS11535 3ebe2700eb715001e31865fa3360c35f 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CWM22_RS11535 3ebe2700eb715001e31865fa3360c35f 130 Gene3D G3DSA:3.30.230.10 3 130 4.2E-53 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS11535 3ebe2700eb715001e31865fa3360c35f 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.434 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CWM22_RS11535 3ebe2700eb715001e31865fa3360c35f 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 2.0E-47 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CWM22_RS11535 3ebe2700eb715001e31865fa3360c35f 130 SUPERFAMILY SSF54211 6 130 1.78E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 SUPERFAMILY SSF53474 148 549 5.85E-95 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 Gene3D G3DSA:2.60.120.260 543 755 9.0E-29 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 Pfam PF09168 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal 1 142 4.3E-41 T 28-03-2018 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 SMART SM00940 1 143 1.0E-70 T 28-03-2018 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 168 178 8.8E-37 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 186 195 8.8E-37 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 370 386 8.8E-37 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 505 521 8.8E-37 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 200 216 8.8E-37 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 152 164 8.8E-37 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 720 735 8.8E-37 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 SMART SM00939 513 752 9.8E-58 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 SUPERFAMILY SSF49785 548 755 2.76E-70 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 Gene3D G3DSA:3.40.50.1820 148 542 5.3E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 SUPERFAMILY SSF81761 1 144 1.18E-41 T 28-03-2018 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 Hamap MF_00698 Xaa-Pro dipeptidyl-peptidase [pepX]. 1 755 34.333 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 188 499 1.3E-72 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CWM22_RS01245 c181f7fab7bcf8fdd20d5f4656f07191 755 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 528 749 9.2E-26 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 SMART SM01061 2 60 1.1E-22 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 Gene3D G3DSA:1.10.1790.10 167 277 5.5E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 Gene3D G3DSA:1.10.1790.10 53 166 5.7E-16 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 SUPERFAMILY SSF63520 58 164 4.71E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 Pfam PF00874 PRD domain 189 275 1.5E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 Pfam PF00874 PRD domain 78 162 2.0E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 SUPERFAMILY SSF50151 2 55 4.71E-14 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 SUPERFAMILY SSF63520 174 276 1.19E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 Gene3D G3DSA:2.30.24.10 1 52 2.4E-20 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWM22_RS01640 b413c0322c3ee8ba894664bb913d8c9f 277 Pfam PF03123 CAT RNA binding domain 3 57 1.6E-17 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 SMART SM00359 276 349 6.4E-11 T 28-03-2018 IPR002478 PUA domain GO:0003723 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 SUPERFAMILY SSF88697 278 356 2.65E-13 T 28-03-2018 IPR015947 PUA-like domain CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 Pfam PF00696 Amino acid kinase family 5 234 3.3E-44 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 258 35.934 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 339 1.2E-127 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 Gene3D G3DSA:3.40.1160.10 1 264 2.6E-66 T 28-03-2018 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 PIRSF PIRSF000729 1 355 3.8E-129 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 SUPERFAMILY SSF53633 4 255 2.23E-69 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 8.8E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 8.8E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 8.8E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 8.8E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 8.8E-49 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 Pfam PF01472 PUA domain 277 338 1.7E-15 T 28-03-2018 IPR002478 PUA domain GO:0003723 CWM22_RS03495 b6ce750888e17e8fb0739c235c952f9a 358 Gene3D G3DSA:2.30.130.10 274 350 1.6E-13 T 28-03-2018 IPR002478 PUA domain GO:0003723 CWM22_RS09940 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:3.30.420.10 172 317 2.6E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS09940 df7b3c790effeebf3da47f303431e10c 317 SUPERFAMILY SSF53098 175 316 5.77E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS09940 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:1.10.10.60 8 55 3.2E-13 T 28-03-2018 CWM22_RS09940 df7b3c790effeebf3da47f303431e10c 317 Pfam PF13936 Helix-turn-helix domain 8 51 3.4E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CWM22_RS09940 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:1.10.10.10 81 150 0.035 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08315 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:3.30.420.10 172 317 2.6E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS08315 df7b3c790effeebf3da47f303431e10c 317 SUPERFAMILY SSF53098 175 316 5.77E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS08315 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:1.10.10.60 8 55 3.2E-13 T 28-03-2018 CWM22_RS08315 df7b3c790effeebf3da47f303431e10c 317 Pfam PF13936 Helix-turn-helix domain 8 51 3.4E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CWM22_RS08315 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:1.10.10.10 81 150 0.035 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS00645 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:3.30.420.10 172 317 2.6E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS00645 df7b3c790effeebf3da47f303431e10c 317 SUPERFAMILY SSF53098 175 316 5.77E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS00645 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:1.10.10.60 8 55 3.2E-13 T 28-03-2018 CWM22_RS00645 df7b3c790effeebf3da47f303431e10c 317 Pfam PF13936 Helix-turn-helix domain 8 51 3.4E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CWM22_RS00645 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:1.10.10.10 81 150 0.035 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS04220 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:3.30.420.10 172 317 2.6E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS04220 df7b3c790effeebf3da47f303431e10c 317 SUPERFAMILY SSF53098 175 316 5.77E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS04220 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:1.10.10.60 8 55 3.2E-13 T 28-03-2018 CWM22_RS04220 df7b3c790effeebf3da47f303431e10c 317 Pfam PF13936 Helix-turn-helix domain 8 51 3.4E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CWM22_RS04220 df7b3c790effeebf3da47f303431e10c 317 Gene3D G3DSA:1.10.10.10 81 150 0.035 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 Gene3D G3DSA:3.90.930.12 83 178 4.0E-38 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.7E-29 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.7E-29 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.7E-29 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 Pfam PF00347 Ribosomal protein L6 12 82 6.1E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 Pfam PF00347 Ribosomal protein L6 91 164 4.9E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 9.5E-73 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 SUPERFAMILY SSF56053 1 82 6.28E-25 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 PIRSF PIRSF002162 1 177 1.8E-44 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.987 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 SUPERFAMILY SSF56053 83 177 1.44E-35 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00570 e837f32328ed7302f6ca3a893048243d 178 Gene3D G3DSA:3.90.930.12 2 82 9.5E-27 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS12625 c04a0d58d3ea036b2ca417b22c4a7be6 286 Pfam PF00950 ABC 3 transport family 12 274 2.2E-48 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CWM22_RS12625 c04a0d58d3ea036b2ca417b22c4a7be6 286 Gene3D G3DSA:1.10.3470.10 4 285 5.1E-21 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS12625 c04a0d58d3ea036b2ca417b22c4a7be6 286 SUPERFAMILY SSF81345 14 262 6.54E-20 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWM22_RS13250 36c071bcafcdef7f038d50ce9a4080b6 653 SUPERFAMILY SSF64182 338 641 1.07E-64 T 28-03-2018 CWM22_RS13250 36c071bcafcdef7f038d50ce9a4080b6 653 PIRSF PIRSF026583 1 653 5.5E-235 T 28-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CWM22_RS13250 36c071bcafcdef7f038d50ce9a4080b6 653 Pfam PF01368 DHH family 340 494 6.8E-19 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWM22_RS13250 36c071bcafcdef7f038d50ce9a4080b6 653 Pfam PF02272 DHHA1 domain 520 643 1.3E-13 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWM22_RS13250 36c071bcafcdef7f038d50ce9a4080b6 653 Gene3D G3DSA:3.90.1640.10 324 538 6.8E-41 T 28-03-2018 CWM22_RS13250 36c071bcafcdef7f038d50ce9a4080b6 653 Gene3D G3DSA:3.30.70.270 152 298 9.5E-4 T 28-03-2018 CWM22_RS10770 06147e23dcd7bf0ba6d3d76ba1007a96 286 SMART SM00382 34 226 1.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS10770 06147e23dcd7bf0ba6d3d76ba1007a96 286 SUPERFAMILY SSF52540 5 248 4.02E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10770 06147e23dcd7bf0ba6d3d76ba1007a96 286 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS10770 06147e23dcd7bf0ba6d3d76ba1007a96 286 Pfam PF00005 ABC transporter 26 176 1.0E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS10770 06147e23dcd7bf0ba6d3d76ba1007a96 286 Gene3D G3DSA:3.40.50.300 2 284 8.1E-67 T 28-03-2018 CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 42 55 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 Pfam PF00005 ABC transporter 33 180 5.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 Pfam PF00005 ABC transporter 297 427 2.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 SMART SM00382 38 234 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 SMART SM00382 301 475 8.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 Gene3D G3DSA:3.40.50.300 7 257 7.9E-60 T 28-03-2018 CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 Gene3D G3DSA:3.40.50.300 272 476 1.3E-43 T 28-03-2018 CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 SUPERFAMILY SSF52540 274 473 2.4E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01795 785b63bb81e2d598dac80a53eb984550 478 SUPERFAMILY SSF52540 10 241 5.66E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08530 11dc96c7dc1a842c59007450ace68e62 305 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 11 298 5.0E-28 T 28-03-2018 IPR010106 Recombination-promoting nuclease RpnA CWM22_RS08530 11dc96c7dc1a842c59007450ace68e62 305 Pfam PF12784 PD-(D/E)XK nuclease family transposase 10 227 1.2E-18 T 28-03-2018 CWM22_RS08530 11dc96c7dc1a842c59007450ace68e62 305 Gene3D G3DSA:1.10.10.60 248 297 2.0E-8 T 28-03-2018 CWM22_RS05055 14cda42308df4ef2eda8bbfdfd2e4e5d 252 Pfam PF00005 ABC transporter 21 177 1.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05055 14cda42308df4ef2eda8bbfdfd2e4e5d 252 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05055 14cda42308df4ef2eda8bbfdfd2e4e5d 252 SMART SM00382 30 240 3.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05055 14cda42308df4ef2eda8bbfdfd2e4e5d 252 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 6 252 7.7E-118 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CWM22_RS05055 14cda42308df4ef2eda8bbfdfd2e4e5d 252 SUPERFAMILY SSF52540 4 238 8.52E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05055 14cda42308df4ef2eda8bbfdfd2e4e5d 252 Gene3D G3DSA:3.40.50.300 2 250 1.9E-58 T 28-03-2018 CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 Pfam PF07702 UTRA domain 96 234 4.3E-41 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 4.7E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 SMART SM00345 14 72 7.0E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 SUPERFAMILY SSF64288 60 240 1.43E-50 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 2.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 2.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 SMART SM00866 94 234 3.6E-41 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 Gene3D G3DSA:3.40.1410.10 79 242 3.7E-45 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 Gene3D G3DSA:1.10.10.10 1 78 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02650 dac5f202b788a045035beffcb0a9fcca 243 SUPERFAMILY SSF46785 4 76 7.16E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03705 76c2bf095d5ffc2678d28d99ae0af294 305 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 303 29.227 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CWM22_RS03705 76c2bf095d5ffc2678d28d99ae0af294 305 Gene3D G3DSA:3.10.28.10 11 97 4.8E-9 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CWM22_RS03705 76c2bf095d5ffc2678d28d99ae0af294 305 Pfam PF02650 WhiA C-terminal HTH domain 218 300 4.4E-30 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CWM22_RS03705 76c2bf095d5ffc2678d28d99ae0af294 305 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 16 99 3.3E-29 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CWM22_RS03705 76c2bf095d5ffc2678d28d99ae0af294 305 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 301 8.4E-107 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CWM22_RS03705 76c2bf095d5ffc2678d28d99ae0af294 305 Gene3D G3DSA:3.10.28.10 121 200 4.3E-14 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CWM22_RS03705 76c2bf095d5ffc2678d28d99ae0af294 305 Pfam PF14527 WhiA LAGLIDADG-like domain 122 214 1.5E-29 T 28-03-2018 CWM22_RS03705 76c2bf095d5ffc2678d28d99ae0af294 305 SUPERFAMILY SSF55608 117 217 1.36E-12 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 Gene3D G3DSA:3.40.50.720 1 232 3.1E-52 T 28-03-2018 CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 8.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 213 8.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 63 74 8.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 127 8.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 156 8.2E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 156 2.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 63 74 2.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 125 2.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 SUPERFAMILY SSF51735 3 231 8.29E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 124 152 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWM22_RS03275 2fe2793dbbd327c88c915f8022d28dc3 232 Pfam PF00106 short chain dehydrogenase 3 179 3.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS03170 5035d835585f9a898c6dfd7242d64af6 313 Gene3D G3DSA:2.60.120.10 233 313 1.3E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWM22_RS03170 5035d835585f9a898c6dfd7242d64af6 313 PIRSF PIRSF036894 1 313 1.6E-128 T 28-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CWM22_RS03170 5035d835585f9a898c6dfd7242d64af6 313 SUPERFAMILY SSF51182 1 310 2.57E-102 T 28-03-2018 IPR011051 RmlC-like cupin domain CWM22_RS03170 5035d835585f9a898c6dfd7242d64af6 313 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 104 311 1.2E-43 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CWM22_RS03170 5035d835585f9a898c6dfd7242d64af6 313 Pfam PF01238 Phosphomannose isomerase type I 4 311 1.5E-53 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CWM22_RS03170 5035d835585f9a898c6dfd7242d64af6 313 Gene3D G3DSA:2.60.120.10 1 219 1.2E-56 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWM22_RS03985 471a982595026e065f3c4dc3ab41db82 109 Pfam PF08774 VRR-NUC domain 4 94 1.1E-10 T 28-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 CWM22_RS03985 471a982595026e065f3c4dc3ab41db82 109 SMART SM00990 2 95 6.7E-17 T 28-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 CWM22_RS05740 a9c2c16427f0741d2aa130e4f1fe0bd1 284 SUPERFAMILY SSF109709 96 215 1.27E-15 T 28-03-2018 CWM22_RS05740 a9c2c16427f0741d2aa130e4f1fe0bd1 284 Gene3D G3DSA:3.90.1530.10 1 98 1.4E-27 T 28-03-2018 CWM22_RS05740 a9c2c16427f0741d2aa130e4f1fe0bd1 284 Pfam PF02195 ParB-like nuclease domain 10 92 3.6E-17 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS05740 a9c2c16427f0741d2aa130e4f1fe0bd1 284 Gene3D G3DSA:1.10.10.730 99 163 1.9E-12 T 28-03-2018 CWM22_RS05740 a9c2c16427f0741d2aa130e4f1fe0bd1 284 SMART SM00470 7 98 1.9E-16 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS05740 a9c2c16427f0741d2aa130e4f1fe0bd1 284 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 4 193 8.3E-25 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CWM22_RS05740 a9c2c16427f0741d2aa130e4f1fe0bd1 284 SUPERFAMILY SSF110849 7 119 2.44E-22 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS06460 a9c2c16427f0741d2aa130e4f1fe0bd1 284 SUPERFAMILY SSF109709 96 215 1.27E-15 T 28-03-2018 CWM22_RS06460 a9c2c16427f0741d2aa130e4f1fe0bd1 284 Gene3D G3DSA:3.90.1530.10 1 98 1.4E-27 T 28-03-2018 CWM22_RS06460 a9c2c16427f0741d2aa130e4f1fe0bd1 284 Pfam PF02195 ParB-like nuclease domain 10 92 3.6E-17 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS06460 a9c2c16427f0741d2aa130e4f1fe0bd1 284 Gene3D G3DSA:1.10.10.730 99 163 1.9E-12 T 28-03-2018 CWM22_RS06460 a9c2c16427f0741d2aa130e4f1fe0bd1 284 SMART SM00470 7 98 1.9E-16 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS06460 a9c2c16427f0741d2aa130e4f1fe0bd1 284 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 4 193 8.3E-25 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CWM22_RS06460 a9c2c16427f0741d2aa130e4f1fe0bd1 284 SUPERFAMILY SSF110849 7 119 2.44E-22 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS06660 ac6e8d7d8b7997be1ad8479dfd723f4c 388 SUPERFAMILY SSF56059 91 325 2.65E-30 T 28-03-2018 CWM22_RS06660 ac6e8d7d8b7997be1ad8479dfd723f4c 388 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 284 9.1E-7 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWM22_RS06660 ac6e8d7d8b7997be1ad8479dfd723f4c 388 Gene3D G3DSA:3.40.50.20 18 116 0.0018 T 28-03-2018 CWM22_RS06660 ac6e8d7d8b7997be1ad8479dfd723f4c 388 Gene3D G3DSA:3.30.470.20 117 381 1.1E-28 T 28-03-2018 CWM22_RS10120 29ebcb6c027bcc41fcfb1224b6ee205e 309 Gene3D G3DSA:3.20.20.70 5 269 4.7E-6 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS10120 29ebcb6c027bcc41fcfb1224b6ee205e 309 Pfam PF01136 Peptidase family U32 74 303 1.0E-42 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWM22_RS10120 29ebcb6c027bcc41fcfb1224b6ee205e 309 SUPERFAMILY SSF102114 14 94 1.1E-5 T 28-03-2018 CWM22_RS12510 4b7f4b4dd37e76db134e300a2f6d6816 221 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 211 4.5E-27 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS12510 4b7f4b4dd37e76db134e300a2f6d6816 221 SMART SM00934 7 212 7.9E-29 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS12510 4b7f4b4dd37e76db134e300a2f6d6816 221 SUPERFAMILY SSF51366 5 216 1.27E-36 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWM22_RS12510 4b7f4b4dd37e76db134e300a2f6d6816 221 Gene3D G3DSA:3.20.20.70 4 221 1.1E-26 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS13025 ab4e8c53f75fb149b34ec53ea4e99488 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS13025 ab4e8c53f75fb149b34ec53ea4e99488 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS13025 ab4e8c53f75fb149b34ec53ea4e99488 450 Pfam PF03050 Transposase IS66 family 117 393 2.8E-82 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS07020 6d23235ac1acc04b565a200b73b02548 172 Pfam PF05239 PRC-barrel domain 97 166 2.3E-10 T 28-03-2018 IPR027275 PRC-barrel domain CWM22_RS07020 6d23235ac1acc04b565a200b73b02548 172 Gene3D G3DSA:2.30.30.240 95 163 7.8E-19 T 28-03-2018 CWM22_RS07020 6d23235ac1acc04b565a200b73b02548 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 167 1.5E-48 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CWM22_RS07020 6d23235ac1acc04b565a200b73b02548 172 Pfam PF01782 RimM N-terminal domain 6 89 4.6E-18 T 28-03-2018 IPR002676 RimM protein GO:0006364 CWM22_RS07020 6d23235ac1acc04b565a200b73b02548 172 Gene3D G3DSA:2.40.30.60 1 94 1.2E-19 T 28-03-2018 IPR002676 RimM protein GO:0006364 CWM22_RS07020 6d23235ac1acc04b565a200b73b02548 172 SUPERFAMILY SSF50346 99 168 1.31E-17 T 28-03-2018 IPR011033 PRC-barrel-like CWM22_RS07020 6d23235ac1acc04b565a200b73b02548 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 3 168 23.077 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CWM22_RS07020 6d23235ac1acc04b565a200b73b02548 172 SUPERFAMILY SSF50447 2 91 8.12E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS09935 48a97434590e249bc5b31e821b905ee9 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS09935 48a97434590e249bc5b31e821b905ee9 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 231 301 4.3E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS07640 48a97434590e249bc5b31e821b905ee9 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS07640 48a97434590e249bc5b31e821b905ee9 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 231 301 4.3E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS06880 546dd81da174dcf496c2e8b19c8d87a9 277 Gene3D G3DSA:3.40.50.150 80 277 2.4E-46 T 28-03-2018 CWM22_RS06880 546dd81da174dcf496c2e8b19c8d87a9 277 Gene3D G3DSA:1.10.8.10 1 79 1.6E-11 T 28-03-2018 CWM22_RS06880 546dd81da174dcf496c2e8b19c8d87a9 277 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWM22_RS06880 546dd81da174dcf496c2e8b19c8d87a9 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 42 273 2.8E-69 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CWM22_RS06880 546dd81da174dcf496c2e8b19c8d87a9 277 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 32 271 1.3E-82 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CWM22_RS06880 546dd81da174dcf496c2e8b19c8d87a9 277 Pfam PF05175 Methyltransferase small domain 106 191 8.1E-22 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CWM22_RS06880 546dd81da174dcf496c2e8b19c8d87a9 277 SUPERFAMILY SSF53335 4 269 3.19E-53 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS06880 546dd81da174dcf496c2e8b19c8d87a9 277 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 275 41.549 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 SUPERFAMILY SSF64288 55 230 4.87E-47 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 Gene3D G3DSA:1.10.10.10 1 66 1.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 4.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 SUPERFAMILY SSF46785 4 76 9.37E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 SMART SM00345 8 67 3.1E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 SMART SM00866 88 226 1.7E-38 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 Pfam PF07702 UTRA domain 89 226 2.1E-38 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWM22_RS06735 e842fe78e20cd32ffd7a5d0c30cd6ec7 232 Gene3D G3DSA:3.40.1410.10 67 232 9.5E-40 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWM22_RS00970 6775b19111b91672e53cb5fd5c6c3aa1 106 Pfam PF00085 Thioredoxin 14 101 5.1E-15 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWM22_RS00970 6775b19111b91672e53cb5fd5c6c3aa1 106 Gene3D G3DSA:3.40.30.10 5 105 2.3E-20 T 28-03-2018 CWM22_RS00970 6775b19111b91672e53cb5fd5c6c3aa1 106 SUPERFAMILY SSF52833 5 102 3.28E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 ProSitePatterns PS00449 ATP synthase a subunit signature. 166 175 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 PRINTS PR00123 ATP synthase A subunit signature 79 95 1.0E-20 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 PRINTS PR00123 ATP synthase A subunit signature 163 185 1.0E-20 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 PRINTS PR00123 ATP synthase A subunit signature 147 162 1.0E-20 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 PRINTS PR00123 ATP synthase A subunit signature 216 231 1.0E-20 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 16 232 7.2E-44 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 Pfam PF00119 ATP synthase A chain 21 229 2.6E-48 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 Gene3D G3DSA:1.20.120.220 9 236 3.4E-31 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 SUPERFAMILY SSF81336 72 230 4.05E-36 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08185 f915eeec4fcf9814c1ed3b11c8d75584 238 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 236 13.233 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS10450 d36677373f0426a7279ce38c3c207e59 314 Pfam PF02096 60Kd inner membrane protein 70 258 1.1E-36 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWM22_RS10450 d36677373f0426a7279ce38c3c207e59 314 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 14 262 27.258 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CWM22_RS10450 d36677373f0426a7279ce38c3c207e59 314 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 70 258 7.4E-41 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CWM22_RS00585 d20e88eaa3118401272b2b7e73b5113f 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 4.8E-19 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CWM22_RS00585 d20e88eaa3118401272b2b7e73b5113f 60 SUPERFAMILY SSF55129 1 59 1.01E-20 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CWM22_RS00585 d20e88eaa3118401272b2b7e73b5113f 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site CWM22_RS00585 d20e88eaa3118401272b2b7e73b5113f 60 PIRSF PIRSF002211 1 60 4.0E-28 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00585 d20e88eaa3118401272b2b7e73b5113f 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.227 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00585 d20e88eaa3118401272b2b7e73b5113f 60 Gene3D G3DSA:3.30.1390.20 4 58 1.1E-23 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CWM22_RS00585 d20e88eaa3118401272b2b7e73b5113f 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 9.1E-28 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS10175 0bc9c50c7cce6feb7890b5003d949d13 280 SUPERFAMILY SSF54593 6 153 2.89E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS10175 0bc9c50c7cce6feb7890b5003d949d13 280 Gene3D G3DSA:3.10.180.10 157 278 1.1E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS10175 0bc9c50c7cce6feb7890b5003d949d13 280 SUPERFAMILY SSF54593 158 277 1.69E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS10175 0bc9c50c7cce6feb7890b5003d949d13 280 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 119 2.2E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWM22_RS10175 0bc9c50c7cce6feb7890b5003d949d13 280 Gene3D G3DSA:3.10.180.10 6 149 3.9E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS10215 0574f9ca6b028449dfa9eececb35bfb8 536 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWM22_RS10215 0574f9ca6b028449dfa9eececb35bfb8 536 Pfam PF01555 DNA methylase 114 413 5.2E-43 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CWM22_RS10215 0574f9ca6b028449dfa9eececb35bfb8 536 PIRSF PIRSF015855 3 506 1.1E-97 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CWM22_RS10215 0574f9ca6b028449dfa9eececb35bfb8 536 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 379 393 6.3E-12 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CWM22_RS10215 0574f9ca6b028449dfa9eececb35bfb8 536 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 155 174 6.3E-12 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CWM22_RS10215 0574f9ca6b028449dfa9eececb35bfb8 536 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 114 126 6.3E-12 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CWM22_RS10215 0574f9ca6b028449dfa9eececb35bfb8 536 Gene3D G3DSA:3.40.50.150 91 435 1.4E-55 T 28-03-2018 CWM22_RS10215 0574f9ca6b028449dfa9eececb35bfb8 536 SUPERFAMILY SSF53335 90 278 3.44E-56 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS10215 0574f9ca6b028449dfa9eececb35bfb8 536 SUPERFAMILY SSF53335 330 431 3.44E-56 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS04035 ac8127da0a94d5ecd76d4999f0a3a714 282 Pfam PF01145 SPFH domain / Band 7 family 36 217 1.2E-24 T 28-03-2018 IPR001107 Band 7 domain CWM22_RS04035 ac8127da0a94d5ecd76d4999f0a3a714 282 SUPERFAMILY SSF117892 65 201 6.67E-12 T 28-03-2018 IPR001107 Band 7 domain CWM22_RS04035 ac8127da0a94d5ecd76d4999f0a3a714 282 SMART SM00244 32 198 1.1E-7 T 28-03-2018 IPR001107 Band 7 domain CWM22_RS11615 139e25cff5f926b808feffcb3b08acf7 493 Gene3D G3DSA:3.40.190.10 158 490 9.7E-23 T 28-03-2018 CWM22_RS11615 139e25cff5f926b808feffcb3b08acf7 493 Pfam PF01547 Bacterial extracellular solute-binding protein 68 347 1.6E-7 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CWM22_RS11615 139e25cff5f926b808feffcb3b08acf7 493 Pfam PF12010 Domain of unknown function (DUF3502) 358 491 4.5E-31 T 28-03-2018 IPR022627 Domain of unknown function DUF3502 CWM22_RS11615 139e25cff5f926b808feffcb3b08acf7 493 SUPERFAMILY SSF53850 22 489 1.75E-72 T 28-03-2018 CWM22_RS13205 2e9c894771400d5ebab41aec01424d02 505 Gene3D G3DSA:3.90.700.10 327 436 7.1E-32 T 28-03-2018 CWM22_RS13205 2e9c894771400d5ebab41aec01424d02 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 65 84 1.2E-5 T 28-03-2018 CWM22_RS13205 2e9c894771400d5ebab41aec01424d02 505 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 449 471 1.2E-5 T 28-03-2018 CWM22_RS13205 2e9c894771400d5ebab41aec01424d02 505 Pfam PF00890 FAD binding domain 64 485 9.1E-99 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWM22_RS13205 2e9c894771400d5ebab41aec01424d02 505 SUPERFAMILY SSF51905 444 504 2.32E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS13205 2e9c894771400d5ebab41aec01424d02 505 SUPERFAMILY SSF51905 54 316 2.32E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS13205 2e9c894771400d5ebab41aec01424d02 505 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 64 497 1.9E-164 T 28-03-2018 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 CWM22_RS13205 2e9c894771400d5ebab41aec01424d02 505 SUPERFAMILY SSF56425 294 440 2.24E-43 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWM22_RS13205 2e9c894771400d5ebab41aec01424d02 505 Gene3D G3DSA:3.50.50.60 46 326 7.7E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07520 c90dc22d4754591feb3077bab850ab87 107 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 101 2.0E-31 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS07520 c90dc22d4754591feb3077bab850ab87 107 PIRSF PIRSF000699 1 107 2.7E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS07520 c90dc22d4754591feb3077bab850ab87 107 Gene3D G3DSA:1.20.58.80 5 102 3.3E-32 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS07520 c90dc22d4754591feb3077bab850ab87 107 SUPERFAMILY SSF46973 6 101 4.84E-32 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS03230 99ff908f64b70e482dce9118bb0d6ee5 330 SUPERFAMILY SSF55874 168 322 1.44E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS03230 99ff908f64b70e482dce9118bb0d6ee5 330 Gene3D G3DSA:3.30.565.10 145 322 1.2E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS03230 99ff908f64b70e482dce9118bb0d6ee5 330 SMART SM00387 220 326 8.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS03230 99ff908f64b70e482dce9118bb0d6ee5 330 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 221 323 4.9E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS00535 eeae784f2b5bfb9e04db99fddc813634 68 TIGRFAM TIGR00012 L29: ribosomal protein uL29 12 66 2.4E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00535 eeae784f2b5bfb9e04db99fddc813634 68 SUPERFAMILY SSF46561 10 67 1.13E-19 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00535 eeae784f2b5bfb9e04db99fddc813634 68 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 67 16.622 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00535 eeae784f2b5bfb9e04db99fddc813634 68 ProSitePatterns PS00579 Ribosomal protein L29 signature. 46 60 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00535 eeae784f2b5bfb9e04db99fddc813634 68 Gene3D G3DSA:1.10.287.310 10 68 1.7E-21 T 28-03-2018 CWM22_RS00535 eeae784f2b5bfb9e04db99fddc813634 68 Pfam PF00831 Ribosomal L29 protein 11 66 8.2E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS03050 c64ed5280af0e5e7dd11163c4cd04950 179 Pfam PF10400 Virulence activator alpha C-term 98 179 2.9E-12 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal CWM22_RS03050 c64ed5280af0e5e7dd11163c4cd04950 179 Gene3D G3DSA:1.10.10.10 1 96 3.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03050 c64ed5280af0e5e7dd11163c4cd04950 179 Pfam PF03551 Transcriptional regulator PadR-like family 20 84 1.7E-9 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWM22_RS03050 c64ed5280af0e5e7dd11163c4cd04950 179 SUPERFAMILY SSF46785 8 178 9.9E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS04695 36595c0f71670fb46cd308c20406940c 63 Gene3D G3DSA:3.30.920.30 1 62 8.8E-19 T 28-03-2018 CWM22_RS04695 36595c0f71670fb46cd308c20406940c 63 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 5 62 1.1E-19 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 CWM22_RS04695 36595c0f71670fb46cd308c20406940c 63 SUPERFAMILY SSF54786 1 62 1.18E-15 T 28-03-2018 CWM22_RS05360 d43d27eb6209c5abb13423aa03cb922e 297 Pfam PF00849 RNA pseudouridylate synthase 85 237 1.3E-30 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS05360 d43d27eb6209c5abb13423aa03cb922e 297 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 33 294 2.1E-67 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS05360 d43d27eb6209c5abb13423aa03cb922e 297 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 128 142 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS05360 d43d27eb6209c5abb13423aa03cb922e 297 SUPERFAMILY SSF55120 70 293 9.92E-69 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS05360 d43d27eb6209c5abb13423aa03cb922e 297 Gene3D G3DSA:3.30.2350.10 76 297 3.3E-65 T 28-03-2018 CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 PRINTS PR01576 Peptide deformylase signature 59 88 1.7E-32 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 PRINTS PR01576 Peptide deformylase signature 129 140 1.7E-32 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 PRINTS PR01576 Peptide deformylase signature 142 160 1.7E-32 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 PRINTS PR01576 Peptide deformylase signature 161 190 1.7E-32 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 18 199 2.0E-42 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 Pfam PF01327 Polypeptide deformylase 17 192 5.7E-47 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 SUPERFAMILY SSF56420 6 201 4.97E-62 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 PIRSF PIRSF004749 4 204 5.4E-49 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 Hamap MF_00163 Peptide deformylase [def]. 15 203 27.021 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS11765 0027d0a9d370bc158c02b61423e161de 204 Gene3D G3DSA:3.90.45.10 15 204 3.8E-52 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS05575 5b4a058166209f325f0c741b70a185e6 117 Pfam PF12666 PrgI family protein 4 95 1.2E-17 T 28-03-2018 IPR024414 Uncharacterised protein family PrgI CWM22_RS07930 cc96d09cc5af94ed29b0061225924083 313 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 300 3.5E-129 T 28-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CWM22_RS07930 cc96d09cc5af94ed29b0061225924083 313 Gene3D G3DSA:3.40.50.880 34 301 2.3E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS07930 cc96d09cc5af94ed29b0061225924083 313 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 5.0E-150 T 28-03-2018 CWM22_RS07930 cc96d09cc5af94ed29b0061225924083 313 SUPERFAMILY SSF52317 17 297 2.14E-98 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS07930 cc96d09cc5af94ed29b0061225924083 313 Pfam PF04204 Homoserine O-succinyltransferase 2 299 2.2E-137 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CWM22_RS07930 cc96d09cc5af94ed29b0061225924083 313 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 53.892 T 28-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CWM22_RS07930 cc96d09cc5af94ed29b0061225924083 313 PIRSF PIRSF000450 1 309 3.0E-149 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CWM22_RS08380 ea3ce7fea1ae9a1c2d09d60f8905d85e 71 Gene3D G3DSA:1.10.10.60 4 30 2.2E-11 T 28-03-2018 CWM22_RS08380 ea3ce7fea1ae9a1c2d09d60f8905d85e 71 Gene3D G3DSA:1.10.260.40 31 63 7.9E-4 T 28-03-2018 CWM22_RS08380 ea3ce7fea1ae9a1c2d09d60f8905d85e 71 SUPERFAMILY SSF47413 5 65 5.63E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS08380 ea3ce7fea1ae9a1c2d09d60f8905d85e 71 Pfam PF01381 Helix-turn-helix 9 59 5.7E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS08380 ea3ce7fea1ae9a1c2d09d60f8905d85e 71 SMART SM00530 8 63 2.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS07030 c2ad2f15dbb3eaa958be7d66be29a543 445 Pfam PF01554 MatE 20 180 1.4E-30 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS07030 c2ad2f15dbb3eaa958be7d66be29a543 445 Pfam PF01554 MatE 246 407 3.2E-30 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS07030 c2ad2f15dbb3eaa958be7d66be29a543 445 PIRSF PIRSF006603 2 445 2.5E-70 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS07030 c2ad2f15dbb3eaa958be7d66be29a543 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 420 3.7E-84 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS10380 85345ef6c0c746b2188c0f41891668fd 189 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 179 33.384 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWM22_RS10380 85345ef6c0c746b2188c0f41891668fd 189 SUPERFAMILY SSF46785 3 78 1.62E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10380 85345ef6c0c746b2188c0f41891668fd 189 SUPERFAMILY SSF46785 83 157 4.63E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10380 85345ef6c0c746b2188c0f41891668fd 189 Gene3D G3DSA:1.10.10.10 83 174 1.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10380 85345ef6c0c746b2188c0f41891668fd 189 Gene3D G3DSA:1.10.10.10 2 82 8.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10380 85345ef6c0c746b2188c0f41891668fd 189 PIRSF PIRSF019345 1 189 6.9E-49 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWM22_RS10380 85345ef6c0c746b2188c0f41891668fd 189 Pfam PF04079 Segregation and condensation complex subunit ScpB 6 165 3.0E-52 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWM22_RS10380 85345ef6c0c746b2188c0f41891668fd 189 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 5 185 3.3E-45 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWM22_RS01565 a106992caa8cce0ba6b3d96f9bcf553c 352 Pfam PF13349 Putative adhesin 52 348 3.2E-12 T 28-03-2018 IPR025164 Putative adhesin CWM22_RS01565 a106992caa8cce0ba6b3d96f9bcf553c 352 Gene3D G3DSA:2.160.20.80 133 345 2.7E-4 T 28-03-2018 CWM22_RS02245 95b292ebddb61f8b032d41cebe33dbfc 210 Gene3D G3DSA:3.40.50.620 19 210 7.9E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS02245 95b292ebddb61f8b032d41cebe33dbfc 210 Pfam PF01467 Cytidylyltransferase-like 28 183 2.7E-32 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWM22_RS02245 95b292ebddb61f8b032d41cebe33dbfc 210 SUPERFAMILY SSF52374 24 210 1.54E-48 T 28-03-2018 CWM22_RS02245 95b292ebddb61f8b032d41cebe33dbfc 210 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 24 210 29.792 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CWM22_RS02245 95b292ebddb61f8b032d41cebe33dbfc 210 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 28 209 3.6E-51 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CWM22_RS02245 95b292ebddb61f8b032d41cebe33dbfc 210 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 89 9.2E-8 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWM22_RS02985 1f3ee4efc89b5d726c871f71d7c84446 91 Gene3D G3DSA:4.10.520.10 1 91 1.7E-35 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CWM22_RS02985 1f3ee4efc89b5d726c871f71d7c84446 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CWM22_RS02985 1f3ee4efc89b5d726c871f71d7c84446 91 SMART SM00411 2 91 1.4E-44 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWM22_RS02985 1f3ee4efc89b5d726c871f71d7c84446 91 SUPERFAMILY SSF47729 3 91 1.47E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CWM22_RS02985 1f3ee4efc89b5d726c871f71d7c84446 91 Pfam PF00216 Bacterial DNA-binding protein 3 91 8.9E-34 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWM22_RS02985 1f3ee4efc89b5d726c871f71d7c84446 91 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.4E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWM22_RS02985 1f3ee4efc89b5d726c871f71d7c84446 91 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.4E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWM22_RS02985 1f3ee4efc89b5d726c871f71d7c84446 91 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.4E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWM22_RS04180 e97586b16f494038a89a0858612d2f6c 239 SUPERFAMILY SSF54001 19 127 2.26E-12 T 28-03-2018 CWM22_RS04180 e97586b16f494038a89a0858612d2f6c 239 Pfam PF08460 Bacterial SH3 domain 162 222 3.7E-14 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CWM22_RS04180 e97586b16f494038a89a0858612d2f6c 239 Gene3D G3DSA:2.30.30.410 140 239 2.8E-15 T 28-03-2018 CWM22_RS04180 e97586b16f494038a89a0858612d2f6c 239 SMART SM00287 163 230 1.3E-10 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CWM22_RS04180 e97586b16f494038a89a0858612d2f6c 239 Pfam PF05257 CHAP domain 24 112 1.9E-12 T 28-03-2018 IPR007921 CHAP domain CWM22_RS02320 2f2fd527a08a7b55291285b4738a70d2 136 Gene3D G3DSA:3.90.45.10 1 136 2.8E-33 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS02320 2f2fd527a08a7b55291285b4738a70d2 136 PIRSF PIRSF004749 2 136 2.0E-30 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS02320 2f2fd527a08a7b55291285b4738a70d2 136 PRINTS PR01576 Peptide deformylase signature 83 94 2.6E-13 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS02320 2f2fd527a08a7b55291285b4738a70d2 136 PRINTS PR01576 Peptide deformylase signature 113 136 2.6E-13 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS02320 2f2fd527a08a7b55291285b4738a70d2 136 PRINTS PR01576 Peptide deformylase signature 30 59 2.6E-13 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS02320 2f2fd527a08a7b55291285b4738a70d2 136 SUPERFAMILY SSF56420 15 136 1.05E-32 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS02320 2f2fd527a08a7b55291285b4738a70d2 136 Pfam PF01327 Polypeptide deformylase 11 136 5.2E-26 T 28-03-2018 IPR023635 Peptide deformylase CWM22_RS03660 6752c7815023d1c9c9989b0f4126db3d 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CWM22_RS03660 6752c7815023d1c9c9989b0f4126db3d 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 230 254 1.4E-12 T 28-03-2018 CWM22_RS03660 6752c7815023d1c9c9989b0f4126db3d 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 199 222 1.4E-12 T 28-03-2018 CWM22_RS03660 6752c7815023d1c9c9989b0f4126db3d 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 163 187 1.4E-12 T 28-03-2018 CWM22_RS03660 6752c7815023d1c9c9989b0f4126db3d 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 116 137 1.4E-12 T 28-03-2018 CWM22_RS03660 6752c7815023d1c9c9989b0f4126db3d 392 Gene3D G3DSA:3.40.640.10 40 279 5.6E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS03660 6752c7815023d1c9c9989b0f4126db3d 392 SUPERFAMILY SSF53383 1 391 1.36E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS03660 6752c7815023d1c9c9989b0f4126db3d 392 Gene3D G3DSA:3.90.1150.10 280 392 3.4E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS03660 6752c7815023d1c9c9989b0f4126db3d 392 Pfam PF00155 Aminotransferase class I and II 32 387 1.8E-73 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWM22_RS08640 bf477632187a3d3ee88d3c3117ccb96a 236 Gene3D G3DSA:3.40.50.300 1 235 2.8E-60 T 28-03-2018 CWM22_RS08640 bf477632187a3d3ee88d3c3117ccb96a 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS08640 bf477632187a3d3ee88d3c3117ccb96a 236 Pfam PF00005 ABC transporter 19 164 2.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS08640 bf477632187a3d3ee88d3c3117ccb96a 236 SUPERFAMILY SSF52540 3 234 1.78E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08640 bf477632187a3d3ee88d3c3117ccb96a 236 SMART SM00382 28 215 3.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS08640 bf477632187a3d3ee88d3c3117ccb96a 236 PIRSF PIRSF039137 1 236 1.2E-109 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CWM22_RS09520 f125ba4c74be2798ff659c088142a7df 187 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 121 4.7E-14 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CWM22_RS09520 f125ba4c74be2798ff659c088142a7df 187 Gene3D G3DSA:1.20.1290.10 16 187 9.5E-31 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CWM22_RS09520 f125ba4c74be2798ff659c088142a7df 187 SUPERFAMILY SSF69118 5 184 1.57E-41 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CWM22_RS09520 f125ba4c74be2798ff659c088142a7df 187 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 60 90 1.7E-10 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CWM22_RS07330 3e7c1ac25e0c7f48742b87fbaea2e8f9 1088 Gene3D G3DSA:3.40.50.300 253 668 1.5E-13 T 28-03-2018 CWM22_RS07330 3e7c1ac25e0c7f48742b87fbaea2e8f9 1088 Pfam PF12705 PD-(D/E)XK nuclease superfamily 757 1042 4.7E-28 T 28-03-2018 CWM22_RS07330 3e7c1ac25e0c7f48742b87fbaea2e8f9 1088 SUPERFAMILY SSF52540 290 660 9.29E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07330 3e7c1ac25e0c7f48742b87fbaea2e8f9 1088 SUPERFAMILY SSF52980 754 946 8.04E-8 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWM22_RS07330 3e7c1ac25e0c7f48742b87fbaea2e8f9 1088 Hamap MF_01453 ATP-dependent helicase/deoxyribonuclease subunit B [rexB]. 1 1087 41.953 T 28-03-2018 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 CWM22_RS07330 3e7c1ac25e0c7f48742b87fbaea2e8f9 1088 TIGRFAM TIGR02774 rexB_recomb: ATP-dependent nuclease subunit B 2 1083 0.0 T 28-03-2018 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 CWM22_RS07330 3e7c1ac25e0c7f48742b87fbaea2e8f9 1088 Gene3D G3DSA:3.40.50.300 1 252 7.5E-27 T 28-03-2018 CWM22_RS07330 3e7c1ac25e0c7f48742b87fbaea2e8f9 1088 Gene3D G3DSA:3.90.320.10 669 958 8.3E-12 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CWM22_RS10870 c3ebffaadf5b5b3cbcd978cf73189ede 1068 SUPERFAMILY SSF52540 232 464 2.49E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10870 c3ebffaadf5b5b3cbcd978cf73189ede 1068 SMART SM00487 278 476 1.7E-15 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS10870 c3ebffaadf5b5b3cbcd978cf73189ede 1068 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 141 747 4.8E-95 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 CWM22_RS10870 c3ebffaadf5b5b3cbcd978cf73189ede 1068 Pfam PF04851 Type III restriction enzyme, res subunit 281 452 1.1E-31 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS10870 c3ebffaadf5b5b3cbcd978cf73189ede 1068 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 768 1059 5.2E-22 T 28-03-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal CWM22_RS10870 c3ebffaadf5b5b3cbcd978cf73189ede 1068 Gene3D G3DSA:3.40.50.300 263 461 6.1E-22 T 28-03-2018 CWM22_RS10870 c3ebffaadf5b5b3cbcd978cf73189ede 1068 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 25 226 8.0E-15 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 CWM22_RS09235 302fe021c84baa31ac30254001989b2a 380 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 8 373 4.8E-172 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWM22_RS09235 302fe021c84baa31ac30254001989b2a 380 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 6 370 56.003 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWM22_RS09235 302fe021c84baa31ac30254001989b2a 380 Pfam PF01702 Queuine tRNA-ribosyltransferase 134 367 3.0E-88 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWM22_RS09235 302fe021c84baa31ac30254001989b2a 380 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 8 373 1.4E-163 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWM22_RS09235 302fe021c84baa31ac30254001989b2a 380 Gene3D G3DSA:3.20.20.105 2 376 5.6E-154 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWM22_RS09235 302fe021c84baa31ac30254001989b2a 380 SUPERFAMILY SSF51713 7 371 5.23E-155 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWM22_RS03595 297559cbf99aa5e2ee949598a5c11199 304 Gene3D G3DSA:3.30.470.20 156 278 0.0011 T 28-03-2018 CWM22_RS03595 297559cbf99aa5e2ee949598a5c11199 304 SUPERFAMILY SSF56059 72 197 2.05E-6 T 28-03-2018 CWM22_RS03595 297559cbf99aa5e2ee949598a5c11199 304 SUPERFAMILY SSF56059 237 283 2.05E-6 T 28-03-2018 CWM22_RS03595 297559cbf99aa5e2ee949598a5c11199 304 Pfam PF14305 TupA-like ATPgrasp 55 297 9.6E-69 T 28-03-2018 IPR029465 TupA-like ATPgrasp protein CWM22_RS12305 627ca6c73fa13523c1b57cc809ad31cf 284 SUPERFAMILY SSF49478 155 231 5.89E-7 T 28-03-2018 CWM22_RS12305 627ca6c73fa13523c1b57cc809ad31cf 284 Gene3D G3DSA:2.60.40.10 55 134 0.0071 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS12305 627ca6c73fa13523c1b57cc809ad31cf 284 Gene3D G3DSA:2.60.40.810 135 252 2.4E-19 T 28-03-2018 CWM22_RS02955 1f8a5bb86f6fc49971afc2a2b99ab0a1 273 Gene3D G3DSA:3.10.290.10 1 64 4.8E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS02955 1f8a5bb86f6fc49971afc2a2b99ab0a1 273 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 239 1.5E-79 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CWM22_RS02955 1f8a5bb86f6fc49971afc2a2b99ab0a1 273 Pfam PF01728 FtsJ-like methyltransferase 62 244 6.2E-18 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CWM22_RS02955 1f8a5bb86f6fc49971afc2a2b99ab0a1 273 Pfam PF01479 S4 domain 4 50 2.7E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS02955 1f8a5bb86f6fc49971afc2a2b99ab0a1 273 PIRSF PIRSF005578 1 267 3.5E-97 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CWM22_RS02955 1f8a5bb86f6fc49971afc2a2b99ab0a1 273 SUPERFAMILY SSF53335 61 247 4.87E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02955 1f8a5bb86f6fc49971afc2a2b99ab0a1 273 Gene3D G3DSA:3.40.50.150 65 273 2.9E-63 T 28-03-2018 CWM22_RS02955 1f8a5bb86f6fc49971afc2a2b99ab0a1 273 SUPERFAMILY SSF55174 3 71 1.47E-8 T 28-03-2018 CWM22_RS02955 1f8a5bb86f6fc49971afc2a2b99ab0a1 273 SMART SM00363 4 71 5.6E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 Gene3D G3DSA:3.50.50.60 2 127 1.1E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 324 7.0E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 Gene3D G3DSA:3.50.50.60 128 334 1.7E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 SUPERFAMILY SSF51905 2 209 6.55E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 1.4E-8 T 28-03-2018 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.4E-8 T 28-03-2018 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.4E-8 T 28-03-2018 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 1.4E-8 T 28-03-2018 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 7.9E-6 T 28-03-2018 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 256 7.9E-6 T 28-03-2018 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.9E-6 T 28-03-2018 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 7.9E-6 T 28-03-2018 CWM22_RS10670 94fae067320e7a1ddf903ac6873fe7ef 630 SUPERFAMILY SSF51905 163 335 7.45E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 SUPERFAMILY SSF55347 138 303 3.33E-52 T 28-03-2018 CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 Gene3D G3DSA:3.40.50.720 1 158 5.0E-30 T 28-03-2018 CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 SUPERFAMILY SSF55021 349 416 9.16E-7 T 28-03-2018 CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 Gene3D G3DSA:3.30.70.260 346 423 3.3E-7 T 28-03-2018 CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 PIRSF PIRSF000098 1 428 2.4E-166 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 Gene3D G3DSA:3.30.360.10 159 299 4.6E-51 T 28-03-2018 CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 Pfam PF00742 Homoserine dehydrogenase 138 316 5.2E-62 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 SUPERFAMILY SSF51735 3 159 7.25E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 130 6.1E-19 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CWM22_RS07125 df4187f48443a53870476bc18d9261b3 428 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWM22_RS02965 c215711ea0c8984fa1ed1316ad3e722c 553 SUPERFAMILY SSF52540 2 50 2.06E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02965 c215711ea0c8984fa1ed1316ad3e722c 553 SUPERFAMILY SSF52540 290 505 2.06E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02965 c215711ea0c8984fa1ed1316ad3e722c 553 PIRSF PIRSF003128 1 553 2.6E-171 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CWM22_RS02965 c215711ea0c8984fa1ed1316ad3e722c 553 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 7.3E-166 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CWM22_RS02965 c215711ea0c8984fa1ed1316ad3e722c 553 SUPERFAMILY SSF52540 1 219 2.13E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02965 c215711ea0c8984fa1ed1316ad3e722c 553 Gene3D G3DSA:3.40.50.300 228 526 1.7E-16 T 28-03-2018 CWM22_RS02965 c215711ea0c8984fa1ed1316ad3e722c 553 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 508 4.8E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CWM22_RS02965 c215711ea0c8984fa1ed1316ad3e722c 553 Gene3D G3DSA:3.40.50.300 1 194 1.3E-24 T 28-03-2018 CWM22_RS06045 1dc09a36f610503730b40c1f790bf298 185 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 92 104 0.17 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS06045 1dc09a36f610503730b40c1f790bf298 185 SUPERFAMILY SSF51161 1 183 9.15E-48 T 28-03-2018 IPR011004 Trimeric LpxA-like CWM22_RS06045 1dc09a36f610503730b40c1f790bf298 185 Gene3D G3DSA:2.160.10.10 1 185 9.5E-46 T 28-03-2018 CWM22_RS06045 1dc09a36f610503730b40c1f790bf298 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 129 163 6.8E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS06045 1dc09a36f610503730b40c1f790bf298 185 SMART SM01266 5 57 5.8E-14 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CWM22_RS06045 1dc09a36f610503730b40c1f790bf298 185 Pfam PF12464 Maltose acetyltransferase 7 56 2.6E-9 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CWM22_RS01030 bffe936288a125dd5ecceb44ed3c82f6 386 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 135 352 5.9E-16 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CWM22_RS01030 bffe936288a125dd5ecceb44ed3c82f6 386 Gene3D G3DSA:3.20.20.190 122 363 5.7E-41 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS01030 bffe936288a125dd5ecceb44ed3c82f6 386 SUPERFAMILY SSF51695 129 358 3.4E-44 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS10150 2b8a7495f0d0944a029fc187c9297b49 115 Pfam PF01638 HxlR-like helix-turn-helix 20 107 3.4E-28 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CWM22_RS10150 2b8a7495f0d0944a029fc187c9297b49 115 Gene3D G3DSA:1.10.10.10 18 106 3.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10150 2b8a7495f0d0944a029fc187c9297b49 115 SUPERFAMILY SSF46785 9 106 6.39E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03960 cb224b7350f94ebf40cb50eedb6cc0a4 229 SUPERFAMILY SSF52540 11 161 1.15E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03960 cb224b7350f94ebf40cb50eedb6cc0a4 229 Gene3D G3DSA:3.40.50.300 3 199 5.2E-6 T 28-03-2018 CWM22_RS03960 cb224b7350f94ebf40cb50eedb6cc0a4 229 Pfam PF13479 AAA domain 16 211 2.9E-32 T 28-03-2018 CWM22_RS03960 cb224b7350f94ebf40cb50eedb6cc0a4 229 TIGRFAM TIGR01618 phage_P_loop: phage nucleotide-binding protein 2 225 1.1E-95 T 28-03-2018 IPR006505 Streptococcus phage Sfi11, Gp233, NTP-binding CWM22_RS00605 da2628bddc9cd71bad3cb18d29afd989 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 7.3E-38 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CWM22_RS00605 da2628bddc9cd71bad3cb18d29afd989 72 SUPERFAMILY SSF50249 1 71 7.29E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS00605 da2628bddc9cd71bad3cb18d29afd989 72 Gene3D G3DSA:2.40.50.140 1 72 1.8E-36 T 28-03-2018 CWM22_RS00605 da2628bddc9cd71bad3cb18d29afd989 72 SMART SM00316 4 72 1.2E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWM22_RS00605 da2628bddc9cd71bad3cb18d29afd989 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.83 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CWM22_RS00605 da2628bddc9cd71bad3cb18d29afd989 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 2.8E-27 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CWM22_RS06500 2e4e8e5fd0ba1b2cf7d58877141167a0 56 SUPERFAMILY SSF47598 24 42 1.38E-7 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CWM22_RS06500 2e4e8e5fd0ba1b2cf7d58877141167a0 56 Gene3D G3DSA:1.10.1220.10 29 42 0.0014 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWM22_RS06500 2e4e8e5fd0ba1b2cf7d58877141167a0 56 Pfam PF07764 Omega Transcriptional Repressor 2 42 2.6E-28 T 28-03-2018 IPR011686 Omega transcriptional repressor CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 Pfam PF00330 Aconitase family (aconitate hydratase) 71 560 7.6E-173 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 PRINTS PR00415 Aconitase family signature 209 224 1.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 PRINTS PR00415 Aconitase family signature 166 174 1.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 PRINTS PR00415 Aconitase family signature 491 504 1.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 PRINTS PR00415 Aconitase family signature 429 440 1.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 PRINTS PR00415 Aconitase family signature 285 298 1.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 PRINTS PR00415 Aconitase family signature 364 378 1.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 PRINTS PR00415 Aconitase family signature 271 284 1.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 PRINTS PR00415 Aconitase family signature 142 155 1.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 PRINTS PR00415 Aconitase family signature 195 208 1.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 ProSitePatterns PS01244 Aconitase family signature 2. 491 504 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 Pfam PF00694 Aconitase C-terminal domain 688 814 1.8E-41 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 Gene3D G3DSA:3.30.499.10 20 231 2.7E-69 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 SUPERFAMILY SSF53732 11 624 1.03E-216 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 Gene3D G3DSA:3.30.499.10 364 574 3.6E-63 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 ProSitePatterns PS00450 Aconitase family signature 1. 425 441 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 SUPERFAMILY SSF52016 630 883 8.24E-79 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 Gene3D G3DSA:3.40.1060.10 232 363 7.9E-43 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 Gene3D G3DSA:3.20.19.10 651 886 8.2E-85 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWM22_RS08330 e9fab36a909203655e1bf20e649681e7 889 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 14 885 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CWM22_RS05780 2e82ddce482ba7ce57086f49fda6066c 358 SMART SM00400 34 79 0.0051 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWM22_RS05780 2e82ddce482ba7ce57086f49fda6066c 358 Pfam PF13155 Toprim-like 200 322 2.4E-10 T 28-03-2018 CWM22_RS05780 2e82ddce482ba7ce57086f49fda6066c 358 Gene3D G3DSA:3.90.580.10 1 82 3.1E-14 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWM22_RS05780 2e82ddce482ba7ce57086f49fda6066c 358 Gene3D G3DSA:3.40.1360.10 183 341 1.6E-21 T 28-03-2018 CWM22_RS05780 2e82ddce482ba7ce57086f49fda6066c 358 Pfam PF13154 Protein of unknown function (DUF3991) 110 183 5.3E-7 T 28-03-2018 IPR025054 Domain of unknown function DUF3991 CWM22_RS05780 2e82ddce482ba7ce57086f49fda6066c 358 Gene3D G3DSA:3.90.980.10 83 182 0.0024 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CWM22_RS05780 2e82ddce482ba7ce57086f49fda6066c 358 SUPERFAMILY SSF57783 4 79 8.5E-13 T 28-03-2018 CWM22_RS08645 532a0e67b2fe94018762564d98f6258a 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 251 2.8E-13 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CWM22_RS08645 532a0e67b2fe94018762564d98f6258a 254 Pfam PF00005 ABC transporter 21 179 9.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS08645 532a0e67b2fe94018762564d98f6258a 254 SMART SM00382 28 228 4.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS08645 532a0e67b2fe94018762564d98f6258a 254 Gene3D G3DSA:3.40.50.300 1 253 5.8E-62 T 28-03-2018 CWM22_RS08645 532a0e67b2fe94018762564d98f6258a 254 SUPERFAMILY SSF52540 3 250 7.48E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05205 06bf80d1398360aa59053ca87e2ae19d 378 Gene3D G3DSA:3.40.50.2000 1 183 7.7E-17 T 28-03-2018 CWM22_RS05205 06bf80d1398360aa59053ca87e2ae19d 378 Pfam PF13439 Glycosyltransferase Family 4 22 161 3.0E-16 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CWM22_RS05205 06bf80d1398360aa59053ca87e2ae19d 378 Pfam PF00534 Glycosyl transferases group 1 185 345 5.2E-36 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWM22_RS05205 06bf80d1398360aa59053ca87e2ae19d 378 Gene3D G3DSA:3.40.50.2000 184 352 1.9E-46 T 28-03-2018 CWM22_RS05205 06bf80d1398360aa59053ca87e2ae19d 378 SUPERFAMILY SSF53756 3 371 8.11E-72 T 28-03-2018 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 Gene3D G3DSA:3.40.50.620 18 623 1.6E-131 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 SUPERFAMILY SSF50677 202 393 8.27E-42 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 Gene3D G3DSA:1.10.730.10 624 792 1.3E-34 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 554 563 3.4E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 3.4E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 520 533 3.4E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 3.4E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 3.4E-26 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 SUPERFAMILY SSF47323 645 917 1.36E-73 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 19.398 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 834 3.6E-279 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 Gene3D G3DSA:3.30.2320.20 793 883 5.0E-23 T 28-03-2018 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 SUPERFAMILY SSF52374 1 200 6.53E-148 T 28-03-2018 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 SUPERFAMILY SSF52374 394 640 6.53E-148 T 28-03-2018 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 Pfam PF08264 Anticodon-binding domain of tRNA 678 830 4.9E-28 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 Pfam PF06827 Zinc finger found in FPG and IleRS 885 914 1.5E-6 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS02850 fa0cfc341a0c2ac0165dc994057f1d13 929 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 634 3.2E-196 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS09880 e20ef06c628befa088e5009ff70deb9b 714 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 637 1.9E-166 T 28-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CWM22_RS09880 e20ef06c628befa088e5009ff70deb9b 714 Pfam PF07670 Nucleoside recognition 512 638 2.1E-26 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWM22_RS09880 e20ef06c628befa088e5009ff70deb9b 714 Pfam PF07670 Nucleoside recognition 351 444 6.5E-12 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWM22_RS09880 e20ef06c628befa088e5009ff70deb9b 714 Pfam PF02421 Ferrous iron transport protein B 4 156 3.4E-64 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CWM22_RS09880 e20ef06c628befa088e5009ff70deb9b 714 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.2E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS09880 e20ef06c628befa088e5009ff70deb9b 714 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.2E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS09880 e20ef06c628befa088e5009ff70deb9b 714 SUPERFAMILY SSF52540 4 169 1.68E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09880 e20ef06c628befa088e5009ff70deb9b 714 Gene3D G3DSA:3.40.50.300 2 339 5.2E-30 T 28-03-2018 CWM22_RS09880 e20ef06c628befa088e5009ff70deb9b 714 Pfam PF07664 Ferrous iron transport protein B C terminus 455 507 3.2E-16 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CWM22_RS11880 55425dfbfcf38e65410e181cf2360f02 251 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 18 250 40.278 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWM22_RS11880 55425dfbfcf38e65410e181cf2360f02 251 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 195 212 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CWM22_RS11880 55425dfbfcf38e65410e181cf2360f02 251 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 18 249 7.9E-84 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWM22_RS11880 55425dfbfcf38e65410e181cf2360f02 251 Gene3D G3DSA:3.40.1180.10 4 251 1.5E-91 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWM22_RS11880 55425dfbfcf38e65410e181cf2360f02 251 Pfam PF01255 Putative undecaprenyl diphosphate synthase 25 249 6.2E-80 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWM22_RS11880 55425dfbfcf38e65410e181cf2360f02 251 SUPERFAMILY SSF64005 18 244 1.12E-86 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 PIRSF PIRSF006809 2 415 4.9E-140 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 Gene3D G3DSA:3.40.50.300 158 410 9.0E-26 T 28-03-2018 CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 201 221 6.4E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 286 6.4E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 Pfam PF13167 GTP-binding GTPase N-terminal 26 113 3.2E-32 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 Pfam PF01926 50S ribosome-binding GTPase 200 318 5.8E-19 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 Pfam PF16360 GTP-binding GTPase Middle Region 115 193 3.9E-29 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 351 5.5E-135 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 SUPERFAMILY SSF52540 192 340 7.21E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07975 d517c7a18224ec80d31103233fa5d221 416 Hamap MF_00900 GTPase HflX [hflX]. 28 385 42.868 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CWM22_RS07720 08d0f1f0db5a8485ac879e1769b268ad 367 SUPERFAMILY SSF51735 5 172 3.63E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS07720 08d0f1f0db5a8485ac879e1769b268ad 367 Gene3D G3DSA:1.10.3660.10 185 302 3.5E-23 T 28-03-2018 CWM22_RS07720 08d0f1f0db5a8485ac879e1769b268ad 367 Pfam PF02153 Prephenate dehydrogenase 17 272 2.1E-72 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CWM22_RS07720 08d0f1f0db5a8485ac879e1769b268ad 367 SUPERFAMILY SSF48179 176 285 1.09E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWM22_RS07720 08d0f1f0db5a8485ac879e1769b268ad 367 Gene3D G3DSA:3.40.50.720 1 175 1.9E-25 T 28-03-2018 CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.1E-19 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.1E-19 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.1E-19 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.571 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 2.0E-44 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 SUPERFAMILY SSF54999 5 102 6.28E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 Gene3D G3DSA:3.30.70.600 3 102 5.8E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 SMART SM01403 7 101 8.2E-56 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00490 db746a5cdd1d17b0e93695e06e650a29 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 6.3E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CWM22_RS05000 24b73fb3d8d8bae2a66a71dac338d040 297 Gene3D G3DSA:3.30.2350.10 1 226 2.4E-80 T 28-03-2018 CWM22_RS05000 24b73fb3d8d8bae2a66a71dac338d040 297 SUPERFAMILY SSF55120 2 229 1.76E-74 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS05000 24b73fb3d8d8bae2a66a71dac338d040 297 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 215 2.1E-73 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS05000 24b73fb3d8d8bae2a66a71dac338d040 297 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 178 229 8.0E-9 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CWM22_RS05000 24b73fb3d8d8bae2a66a71dac338d040 297 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 25 177 2.3E-55 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CWM22_RS05000 24b73fb3d8d8bae2a66a71dac338d040 297 Gene3D G3DSA:2.30.130.10 235 291 2.3E-10 T 28-03-2018 IPR002478 PUA domain GO:0003723 CWM22_RS05000 24b73fb3d8d8bae2a66a71dac338d040 297 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 291 18.295 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS05605 1564af4453a4fe6c456b312b9fd64195 332 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 43 320 4.4E-46 T 28-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CWM22_RS03980 43053c3628797ab1dfef6a4793c2b77b 521 SMART SM00885 76 209 1.2E-7 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CWM22_RS03980 43053c3628797ab1dfef6a4793c2b77b 521 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 160 462 6.6E-95 T 28-03-2018 IPR006500 DNA primase, phage/plasmid CWM22_RS03980 43053c3628797ab1dfef6a4793c2b77b 521 Gene3D G3DSA:3.40.50.300 185 399 7.1E-17 T 28-03-2018 CWM22_RS03980 43053c3628797ab1dfef6a4793c2b77b 521 Pfam PF03288 Poxvirus D5 protein-like 416 491 1.1E-14 T 28-03-2018 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal CWM22_RS03980 43053c3628797ab1dfef6a4793c2b77b 521 SUPERFAMILY SSF52540 199 396 1.12E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05595 3a7dcb2d4ded9ff2d494f3f2bcb19199 933 Gene3D G3DSA:2.70.70.10 420 579 2.5E-5 T 28-03-2018 CWM22_RS05595 3a7dcb2d4ded9ff2d494f3f2bcb19199 933 SUPERFAMILY SSF54001 805 914 1.08E-14 T 28-03-2018 CWM22_RS05595 3a7dcb2d4ded9ff2d494f3f2bcb19199 933 Pfam PF05257 CHAP domain 808 907 5.9E-15 T 28-03-2018 IPR007921 CHAP domain CWM22_RS05225 814d734e467cce478cdeaf71a18e61a9 306 Pfam PF04230 Polysaccharide pyruvyl transferase 13 209 7.7E-7 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase CWM22_RS08190 b118e1405a530e8987eee14e4a75433d 66 ProSitePatterns PS00605 ATP synthase c subunit signature. 31 52 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08190 b118e1405a530e8987eee14e4a75433d 66 Hamap MF_01396 ATP synthase subunit c [atpH]. 1 66 13.541 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08190 b118e1405a530e8987eee14e4a75433d 66 PRINTS PR00124 ATP synthase C subunit signature 41 66 2.8E-12 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08190 b118e1405a530e8987eee14e4a75433d 66 PRINTS PR00124 ATP synthase C subunit signature 3 22 2.8E-12 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08190 b118e1405a530e8987eee14e4a75433d 66 PRINTS PR00124 ATP synthase C subunit signature 24 39 2.8E-12 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWM22_RS08190 b118e1405a530e8987eee14e4a75433d 66 Pfam PF00137 ATP synthase subunit C 5 65 1.2E-9 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWM22_RS08190 b118e1405a530e8987eee14e4a75433d 66 Gene3D G3DSA:1.20.20.10 2 66 3.4E-13 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWM22_RS08190 b118e1405a530e8987eee14e4a75433d 66 SUPERFAMILY SSF81333 5 65 6.54E-14 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWM22_RS08675 51869da16ac560acd33d70ad9351c60d 209 SUPERFAMILY SSF53271 5 207 4.85E-74 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS08675 51869da16ac560acd33d70ad9351c60d 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 3.5E-91 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CWM22_RS08675 51869da16ac560acd33d70ad9351c60d 209 Gene3D G3DSA:3.40.50.2020 3 207 4.0E-68 T 28-03-2018 CWM22_RS08675 51869da16ac560acd33d70ad9351c60d 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 9.1E-79 T 28-03-2018 CWM22_RS08675 51869da16ac560acd33d70ad9351c60d 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.558 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CWM22_RS01020 20d32a9c62bf5ed83f90744b1f82b054 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.69 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CWM22_RS01020 20d32a9c62bf5ed83f90744b1f82b054 156 SUPERFAMILY SSF47973 1 149 1.83E-60 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CWM22_RS01020 20d32a9c62bf5ed83f90744b1f82b054 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS01020 20d32a9c62bf5ed83f90744b1f82b054 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.9E-69 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CWM22_RS01020 20d32a9c62bf5ed83f90744b1f82b054 156 PIRSF PIRSF002122 1 156 1.2E-55 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CWM22_RS01020 20d32a9c62bf5ed83f90744b1f82b054 156 Gene3D G3DSA:1.10.455.10 6 156 7.1E-60 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CWM22_RS01020 20d32a9c62bf5ed83f90744b1f82b054 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 4.2E-66 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 SUPERFAMILY SSF46689 226 274 7.62E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 SMART SM00342 189 272 4.9E-33 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 Pfam PF02311 AraC-like ligand binding domain 18 122 9.8E-22 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 Gene3D G3DSA:2.60.120.280 4 162 5.2E-23 T 28-03-2018 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 256 4.9E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 256 272 4.9E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 Pfam PF12833 Helix-turn-helix domain 195 273 7.4E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 SUPERFAMILY SSF46689 173 223 3.78E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 Gene3D G3DSA:1.10.10.60 223 279 2.9E-13 T 28-03-2018 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 Gene3D G3DSA:1.10.10.60 165 222 2.5E-15 T 28-03-2018 CWM22_RS08725 de368535275bc0a5fae1c66902d90bc5 279 SUPERFAMILY SSF51215 11 158 3.14E-31 T 28-03-2018 CWM22_RS05195 3701f3f7e192449519f6dd7ad9bcb488 161 Pfam PF00583 Acetyltransferase (GNAT) family 47 140 3.6E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS05195 3701f3f7e192449519f6dd7ad9bcb488 161 Gene3D G3DSA:3.40.630.30 2 160 2.2E-20 T 28-03-2018 CWM22_RS05195 3701f3f7e192449519f6dd7ad9bcb488 161 SUPERFAMILY SSF55729 11 147 1.63E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS07460 08229cfed241a1441a5118c02a18ac01 487 Pfam PF05043 Mga helix-turn-helix domain 78 159 4.6E-20 T 28-03-2018 IPR007737 Mga helix-turn-helix domain CWM22_RS07460 08229cfed241a1441a5118c02a18ac01 487 SUPERFAMILY SSF46785 77 130 5.25E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07460 08229cfed241a1441a5118c02a18ac01 487 Gene3D G3DSA:1.10.10.10 5 77 5.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07460 08229cfed241a1441a5118c02a18ac01 487 Gene3D G3DSA:1.10.10.10 90 156 1.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06920 0d3fd305dc4df898ea2c49ddb00bb893 195 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 26 191 3.5E-13 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS06920 0d3fd305dc4df898ea2c49ddb00bb893 195 Gene3D G3DSA:3.40.50.300 4 72 1.0E-14 T 28-03-2018 CWM22_RS06920 0d3fd305dc4df898ea2c49ddb00bb893 195 Pfam PF01926 50S ribosome-binding GTPase 27 145 9.5E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS06920 0d3fd305dc4df898ea2c49ddb00bb893 195 SUPERFAMILY SSF52540 18 193 5.14E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06920 0d3fd305dc4df898ea2c49ddb00bb893 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 9 191 4.5E-73 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CWM22_RS06920 0d3fd305dc4df898ea2c49ddb00bb893 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 195 28.984 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CWM22_RS06920 0d3fd305dc4df898ea2c49ddb00bb893 195 Gene3D G3DSA:3.40.50.300 73 191 5.4E-15 T 28-03-2018 CWM22_RS11415 84fc5ee04930d2e693a1d11d00766f60 278 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 3 272 16.786 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWM22_RS11415 84fc5ee04930d2e693a1d11d00766f60 278 Pfam PF02673 Bacitracin resistance protein BacA 8 267 1.1E-80 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWM22_RS03580 9aec6f8c2b2ce7340e96ea071b43c29d 341 Pfam PF00535 Glycosyl transferase family 2 17 146 2.2E-33 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS03580 9aec6f8c2b2ce7340e96ea071b43c29d 341 Gene3D G3DSA:3.90.550.10 11 318 1.2E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS03580 9aec6f8c2b2ce7340e96ea071b43c29d 341 SUPERFAMILY SSF53448 14 241 3.94E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 372 8.2E-141 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 PIRSF PIRSF001369 1 372 4.6E-147 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 SUPERFAMILY SSF48256 4 372 3.93E-125 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 ProSitePatterns PS00480 Citrate synthase signature. 255 267 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 Pfam PF00285 Citrate synthase, C-terminal domain 6 355 9.0E-123 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 Gene3D G3DSA:1.10.580.10 11 261 8.7E-83 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 Gene3D G3DSA:1.10.580.10 299 352 2.5E-10 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 PRINTS PR00143 Citrate synthase signature 173 188 3.0E-44 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 PRINTS PR00143 Citrate synthase signature 124 137 3.0E-44 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 PRINTS PR00143 Citrate synthase signature 195 223 3.0E-44 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 PRINTS PR00143 Citrate synthase signature 325 339 3.0E-44 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 PRINTS PR00143 Citrate synthase signature 305 321 3.0E-44 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWM22_RS08325 f0b2144ac9815118add7bda16af7c07a 372 PRINTS PR00143 Citrate synthase signature 248 268 3.0E-44 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWM22_RS06235 6f3e67020148f68a781840430ce217a4 279 SUPERFAMILY SSF161098 10 279 6.54E-68 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS06235 6f3e67020148f68a781840430ce217a4 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 268 8.2E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS06235 6f3e67020148f68a781840430ce217a4 279 Gene3D G3DSA:1.10.3720.10 13 274 5.9E-45 T 28-03-2018 CWM22_RS10725 23feb4cdb3f7fc0a92f3d7bfb2a88e46 159 SUPERFAMILY SSF160419 30 155 1.7E-32 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 CWM22_RS10725 23feb4cdb3f7fc0a92f3d7bfb2a88e46 159 Pfam PF07166 Protein of unknown function (DUF1398) 44 152 1.2E-23 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 CWM22_RS10725 23feb4cdb3f7fc0a92f3d7bfb2a88e46 159 Gene3D G3DSA:3.30.1810.10 31 152 8.7E-31 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 CWM22_RS10725 23feb4cdb3f7fc0a92f3d7bfb2a88e46 159 ProDom PD021249 YDFO YCGX ENVELOPE CYTOPLASMIC STY1988 CP-933X ECS1626 YBCV PROPHAGE 66 154 1.0E-4 T 28-03-2018 IPR009833 Uncharacterised protein DUF1398 CWM22_RS10085 317b1642eb1139b53086297888f1f804 388 Gene3D G3DSA:2.40.50.100 73 219 1.9E-10 T 28-03-2018 CWM22_RS10085 317b1642eb1139b53086297888f1f804 388 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 271 3.5E-15 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CWM22_RS10085 317b1642eb1139b53086297888f1f804 388 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 51 381 6.4E-32 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CWM22_RS11410 a522e88d91fe65c84aa7459c3f32148c 240 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 234 4.1E-42 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CWM22_RS11410 a522e88d91fe65c84aa7459c3f32148c 240 Hamap MF_01124 Adapter protein MecA [mecA]. 1 238 23.676 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CWM22_RS11410 a522e88d91fe65c84aa7459c3f32148c 240 PIRSF PIRSF029008 1 239 4.3E-61 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 PRINTS PR00069 Aldo-keto reductase signature 154 183 2.8E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 PRINTS PR00069 Aldo-keto reductase signature 91 109 2.8E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 PRINTS PR00069 Aldo-keto reductase signature 193 217 2.8E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 PRINTS PR00069 Aldo-keto reductase signature 120 137 2.8E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 PRINTS PR00069 Aldo-keto reductase signature 35 59 2.8E-43 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 Gene3D G3DSA:3.20.20.100 1 276 1.0E-91 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 PIRSF PIRSF000097 1 116 5.7E-39 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 PIRSF PIRSF000097 111 277 4.7E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 Pfam PF00248 Aldo/keto reductase family 16 258 1.1E-47 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 SUPERFAMILY SSF51430 2 267 8.64E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWM22_RS01445 f46890799f66ab17fc1bd2b7bcc711da 284 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWM22_RS01520 751c8dfa99f39bb4de789bfb5181afc0 277 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 270 5.0E-46 T 28-03-2018 IPR000150 Cof family GO:0016787 CWM22_RS01520 751c8dfa99f39bb4de789bfb5181afc0 277 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 270 2.6E-53 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS01520 751c8dfa99f39bb4de789bfb5181afc0 277 ProSitePatterns PS01229 Hypothetical cof family signature 2. 224 246 - T 28-03-2018 CWM22_RS01520 751c8dfa99f39bb4de789bfb5181afc0 277 Gene3D G3DSA:3.40.50.1000 1 277 2.4E-30 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS01520 751c8dfa99f39bb4de789bfb5181afc0 277 SUPERFAMILY SSF56784 1 275 2.42E-59 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS05335 f160fd338f0638b4b07cfbc6753c5a95 371 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 191 210 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CWM22_RS05335 f160fd338f0638b4b07cfbc6753c5a95 371 Gene3D G3DSA:3.90.1150.10 239 368 1.5E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS05335 f160fd338f0638b4b07cfbc6753c5a95 371 Gene3D G3DSA:3.40.640.10 10 238 8.2E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS05335 f160fd338f0638b4b07cfbc6753c5a95 371 SUPERFAMILY SSF53383 1 369 2.63E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS05335 f160fd338f0638b4b07cfbc6753c5a95 371 PIRSF PIRSF005572 1 370 5.9E-113 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWM22_RS05335 f160fd338f0638b4b07cfbc6753c5a95 371 Pfam PF00266 Aminotransferase class-V 2 361 9.3E-76 T 28-03-2018 IPR000192 Aminotransferase class V domain CWM22_RS07500 dd625b93ded7a25d659fa13697b6c653 222 SUPERFAMILY SSF51569 1 217 1.05E-59 T 28-03-2018 CWM22_RS07500 dd625b93ded7a25d659fa13697b6c653 222 Gene3D G3DSA:3.20.20.70 1 222 1.2E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS07500 dd625b93ded7a25d659fa13697b6c653 222 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 4 205 1.1E-40 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWM22_RS07500 dd625b93ded7a25d659fa13697b6c653 222 ProSitePatterns PS00958 Transaldolase active site. 84 101 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWM22_RS09500 999cf2c059162be7b7cf116ddd568410 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 264 1.8E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS09500 999cf2c059162be7b7cf116ddd568410 276 SUPERFAMILY SSF161098 11 276 4.11E-67 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS09500 999cf2c059162be7b7cf116ddd568410 276 Gene3D G3DSA:1.10.3720.10 2 263 8.9E-38 T 28-03-2018 CWM22_RS02215 8566f29319a14078e68e387ef5941d70 302 SUPERFAMILY SSF103481 41 148 2.62E-12 T 28-03-2018 CWM22_RS02215 8566f29319a14078e68e387ef5941d70 302 SUPERFAMILY SSF103481 197 293 1.57E-12 T 28-03-2018 CWM22_RS02215 8566f29319a14078e68e387ef5941d70 302 Pfam PF00892 EamA-like transporter family 6 144 2.8E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWM22_RS02215 8566f29319a14078e68e387ef5941d70 302 Pfam PF00892 EamA-like transporter family 157 290 6.3E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWM22_RS08660 59766cd5ef188e6ddac2a68efee67ed1 389 SUPERFAMILY SSF53822 39 379 3.21E-85 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS08660 59766cd5ef188e6ddac2a68efee67ed1 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 103 113 7.9E-9 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CWM22_RS08660 59766cd5ef188e6ddac2a68efee67ed1 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 41 57 7.9E-9 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CWM22_RS08660 59766cd5ef188e6ddac2a68efee67ed1 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 63 79 7.9E-9 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CWM22_RS08660 59766cd5ef188e6ddac2a68efee67ed1 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 82 100 7.9E-9 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CWM22_RS08660 59766cd5ef188e6ddac2a68efee67ed1 389 Gene3D G3DSA:3.40.50.2300 196 370 2.3E-31 T 28-03-2018 CWM22_RS08660 59766cd5ef188e6ddac2a68efee67ed1 389 Pfam PF13458 Periplasmic binding protein 41 378 2.2E-59 T 28-03-2018 IPR028081 Leucine-binding protein domain CWM22_RS08660 59766cd5ef188e6ddac2a68efee67ed1 389 Gene3D G3DSA:3.40.50.2300 24 195 1.3E-37 T 28-03-2018 CWM22_RS12960 36b6baf9b9d8fbad989750cbdcf34688 121 SUPERFAMILY SSF47413 2 67 7.78E-20 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS12960 36b6baf9b9d8fbad989750cbdcf34688 121 Pfam PF01381 Helix-turn-helix 6 60 2.9E-18 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12960 36b6baf9b9d8fbad989750cbdcf34688 121 Gene3D G3DSA:1.10.3100.10 1 120 1.8E-26 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS12960 36b6baf9b9d8fbad989750cbdcf34688 121 SMART SM00530 5 60 7.3E-19 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 Gene3D G3DSA:3.40.50.1980 187 306 1.3E-29 T 28-03-2018 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 SUPERFAMILY SSF53807 32 306 6.87E-67 T 28-03-2018 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00691 Adhesin B signature 244 261 4.7E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00691 Adhesin B signature 140 159 4.7E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00691 Adhesin B signature 33 54 4.7E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00691 Adhesin B signature 76 95 4.7E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00691 Adhesin B signature 196 213 4.7E-6 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 Pfam PF01297 Zinc-uptake complex component A periplasmic 36 303 5.7E-60 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00690 Adhesin family signature 33 51 7.7E-12 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00690 Adhesin family signature 76 93 7.7E-12 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00690 Adhesin family signature 196 217 7.7E-12 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00690 Adhesin family signature 248 266 7.7E-12 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 PRINTS PR00690 Adhesin family signature 63 76 7.7E-12 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWM22_RS02035 e16f39d1cc8bfc52c9b65ebc6a9a4eb7 306 Gene3D G3DSA:3.40.50.1980 22 186 2.2E-38 T 28-03-2018 CWM22_RS06505 734077a546df24a5e28d055d0db74d3a 564 Pfam PF00239 Resolvase, N terminal domain 2 108 1.1E-11 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS06505 734077a546df24a5e28d055d0db74d3a 564 Gene3D G3DSA:3.40.50.1390 1 105 2.8E-28 T 28-03-2018 CWM22_RS06505 734077a546df24a5e28d055d0db74d3a 564 Gene3D G3DSA:3.40.50.300 106 486 3.8E-4 T 28-03-2018 CWM22_RS06505 734077a546df24a5e28d055d0db74d3a 564 Pfam PF14287 Domain of unknown function (DUF4368) 427 493 2.5E-19 T 28-03-2018 IPR025378 Domain of unknown function DUF4368 CWM22_RS06505 734077a546df24a5e28d055d0db74d3a 564 SMART SM00857 1 109 2.6E-7 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS06505 734077a546df24a5e28d055d0db74d3a 564 Pfam PF07508 Recombinase 133 258 9.0E-22 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CWM22_RS06505 734077a546df24a5e28d055d0db74d3a 564 SUPERFAMILY SSF53041 2 109 4.05E-23 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS06505 734077a546df24a5e28d055d0db74d3a 564 Pfam PF13408 Recombinase zinc beta ribbon domain 271 335 7.6E-10 T 28-03-2018 IPR025827 Recombinase zinc beta ribbon domain CWM22_RS08780 1e8341ece1b754ec23cdc60b57cb224e 92 Gene3D G3DSA:1.10.10.10 1 92 7.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08780 1e8341ece1b754ec23cdc60b57cb224e 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 6.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWM22_RS08780 1e8341ece1b754ec23cdc60b57cb224e 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 6.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWM22_RS08780 1e8341ece1b754ec23cdc60b57cb224e 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 6.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWM22_RS08780 1e8341ece1b754ec23cdc60b57cb224e 92 SMART SM00418 5 83 2.7E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWM22_RS08780 1e8341ece1b754ec23cdc60b57cb224e 92 SUPERFAMILY SSF46785 3 83 1.82E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08780 1e8341ece1b754ec23cdc60b57cb224e 92 Pfam PF01022 Bacterial regulatory protein, arsR family 13 56 2.0E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWM22_RS05080 db521bfbf943c88861cbae84a7a3a1ae 409 SUPERFAMILY SSF54001 108 306 3.73E-22 T 28-03-2018 CWM22_RS05080 db521bfbf943c88861cbae84a7a3a1ae 409 Pfam PF01841 Transglutaminase-like superfamily 160 258 1.5E-10 T 28-03-2018 IPR002931 Transglutaminase-like CWM22_RS05080 db521bfbf943c88861cbae84a7a3a1ae 409 SMART SM00460 200 261 1.2E-5 T 28-03-2018 IPR002931 Transglutaminase-like CWM22_RS02830 1ca1be8c8487a42ad0eaae5f6cdf9cac 87 Pfam PF02325 YGGT family 11 78 1.1E-14 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CWM22_RS03480 2ce28c2f7201683def7cabb3c1a42dce 671 Pfam PF01431 Peptidase family M13 478 667 3.8E-50 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CWM22_RS03480 2ce28c2f7201683def7cabb3c1a42dce 671 Gene3D G3DSA:3.40.390.10 342 671 1.1E-75 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CWM22_RS03480 2ce28c2f7201683def7cabb3c1a42dce 671 Pfam PF05649 Peptidase family M13 42 421 3.2E-42 T 28-03-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 CWM22_RS03480 2ce28c2f7201683def7cabb3c1a42dce 671 SUPERFAMILY SSF55486 41 671 5.13E-133 T 28-03-2018 CWM22_RS03480 2ce28c2f7201683def7cabb3c1a42dce 671 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 578 589 4.1E-13 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CWM22_RS03480 2ce28c2f7201683def7cabb3c1a42dce 671 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 508 524 4.1E-13 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CWM22_RS03480 2ce28c2f7201683def7cabb3c1a42dce 671 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 487 499 4.1E-13 T 28-03-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 CWM22_RS01385 d20d1842d2613dc7a6616c44025248c3 541 Pfam PF00128 Alpha amylase, catalytic domain 26 365 7.4E-104 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS01385 d20d1842d2613dc7a6616c44025248c3 541 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 5 539 1.4E-257 T 28-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 CWM22_RS01385 d20d1842d2613dc7a6616c44025248c3 541 SMART SM00642 11 407 7.5E-128 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS01385 d20d1842d2613dc7a6616c44025248c3 541 SUPERFAMILY SSF51445 6 463 1.66E-138 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS01385 d20d1842d2613dc7a6616c44025248c3 541 Gene3D G3DSA:2.60.40.1180 467 541 1.9E-18 T 28-03-2018 CWM22_RS01385 d20d1842d2613dc7a6616c44025248c3 541 Gene3D G3DSA:3.20.20.80 5 466 5.7E-110 T 28-03-2018 CWM22_RS01385 d20d1842d2613dc7a6616c44025248c3 541 SUPERFAMILY SSF51011 466 540 2.22E-16 T 28-03-2018 CWM22_RS01385 d20d1842d2613dc7a6616c44025248c3 541 Pfam PF16657 Maltogenic Amylase, C-terminal domain 466 535 3.4E-9 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal CWM22_RS13360 569d635b58e7f31345a7ee38752afa40 127 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 2 61 1.7E-25 T 28-03-2018 IPR014330 RNA-binding S4-related,YaaA CWM22_RS13360 569d635b58e7f31345a7ee38752afa40 127 Gene3D G3DSA:3.10.290.10 9 117 3.1E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS13360 569d635b58e7f31345a7ee38752afa40 127 Pfam PF13275 S4 domain 3 66 2.6E-22 T 28-03-2018 CWM22_RS13360 569d635b58e7f31345a7ee38752afa40 127 SUPERFAMILY SSF55174 2 65 1.57E-15 T 28-03-2018 CWM22_RS01560 1406668d52dc147f3e5579a7726c6ebb 402 Gene3D G3DSA:3.40.190.10 46 150 9.5E-12 T 28-03-2018 CWM22_RS01560 1406668d52dc147f3e5579a7726c6ebb 402 Pfam PF12698 ABC-2 family transporter protein 19 371 1.3E-38 T 28-03-2018 CWM22_RS10205 9380b19e58dc554cbe88e5b1b1eec003 259 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS10205 9380b19e58dc554cbe88e5b1b1eec003 259 Gene3D G3DSA:3.40.50.300 1 238 4.8E-50 T 28-03-2018 CWM22_RS10205 9380b19e58dc554cbe88e5b1b1eec003 259 Pfam PF00005 ABC transporter 18 168 5.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS10205 9380b19e58dc554cbe88e5b1b1eec003 259 SUPERFAMILY SSF52540 2 231 7.62E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10205 9380b19e58dc554cbe88e5b1b1eec003 259 SMART SM00382 27 219 4.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS07580 ee7f52b45dcefed01bad56a6458af028 182 Gene3D G3DSA:3.40.50.1950 1 182 3.4E-53 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWM22_RS07580 ee7f52b45dcefed01bad56a6458af028 182 Pfam PF02441 Flavoprotein 3 177 3.5E-43 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWM22_RS07580 ee7f52b45dcefed01bad56a6458af028 182 SUPERFAMILY SSF52507 2 176 3.01E-56 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWM22_RS07580 ee7f52b45dcefed01bad56a6458af028 182 TIGRFAM TIGR02113 coaC_strep: phosphopantothenoylcysteine decarboxylase 3 177 2.0E-85 T 28-03-2018 IPR011847 Phosphopantothenoylcysteine decarboxylase KEGG: 00770+4.1.1.36|MetaCyc: PWY-7851 CWM22_RS02860 aa8c845410f76c9d383ba4fedc33f14e 155 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWM22_RS02860 aa8c845410f76c9d383ba4fedc33f14e 155 SUPERFAMILY SSF55811 9 150 1.23E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS02860 aa8c845410f76c9d383ba4fedc33f14e 155 Gene3D G3DSA:3.90.79.10 5 150 1.6E-23 T 28-03-2018 CWM22_RS02860 aa8c845410f76c9d383ba4fedc33f14e 155 Pfam PF00293 NUDIX domain 22 137 8.5E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWM22_RS11705 8b06359c6e83edc5b5bedac46b84dc53 425 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 18 417 2.6E-109 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWM22_RS11705 8b06359c6e83edc5b5bedac46b84dc53 425 Pfam PF00860 Permease family 19 394 2.8E-86 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWM22_RS11705 8b06359c6e83edc5b5bedac46b84dc53 425 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 341 361 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWM22_RS09450 ed9e840f0df0e5ee7e7345a07cda55f0 299 Hamap MF_00367 GTPase Era [era]. 3 294 38.109 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS09450 ed9e840f0df0e5ee7e7345a07cda55f0 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 165 2.3E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWM22_RS09450 ed9e840f0df0e5ee7e7345a07cda55f0 299 SUPERFAMILY SSF52540 8 203 1.19E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09450 ed9e840f0df0e5ee7e7345a07cda55f0 299 SUPERFAMILY SSF54814 179 295 3.6E-42 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWM22_RS09450 ed9e840f0df0e5ee7e7345a07cda55f0 299 Gene3D G3DSA:3.40.50.300 7 195 3.9E-37 T 28-03-2018 CWM22_RS09450 ed9e840f0df0e5ee7e7345a07cda55f0 299 Gene3D G3DSA:3.30.300.20 196 297 4.0E-46 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS09450 ed9e840f0df0e5ee7e7345a07cda55f0 299 Pfam PF01926 50S ribosome-binding GTPase 8 122 5.5E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS09450 ed9e840f0df0e5ee7e7345a07cda55f0 299 Pfam PF07650 KH domain 205 283 3.1E-23 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS09450 ed9e840f0df0e5ee7e7345a07cda55f0 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 6 277 2.2E-106 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 PRINTS PR00303 Preprotein translocase SecY subunit signature 346 364 7.0E-19 T 28-03-2018 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 PRINTS PR00303 Preprotein translocase SecY subunit signature 135 160 7.0E-19 T 28-03-2018 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 PRINTS PR00303 Preprotein translocase SecY subunit signature 380 398 7.0E-19 T 28-03-2018 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 PRINTS PR00303 Preprotein translocase SecY subunit signature 246 265 7.0E-19 T 28-03-2018 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 PRINTS PR00303 Preprotein translocase SecY subunit signature 19 37 7.0E-19 T 28-03-2018 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 7.0E-19 T 28-03-2018 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 Gene3D G3DSA:1.10.3370.10 1 414 5.4E-55 T 28-03-2018 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 TIGRFAM TIGR02920 acc_sec_Y2: accessory Sec system translocase SecY2 15 411 9.5E-87 T 28-03-2018 IPR014269 Accessory Sec system protein translocase subunit SecY2 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 PIRSF PIRSF004557 3 414 5.9E-60 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 Pfam PF00344 SecY translocase 68 391 4.4E-37 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWM22_RS04455 e0c1673533fb94b6c01992ce1e89eb92 414 SUPERFAMILY SSF103491 8 400 9.29E-48 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWM22_RS10950 2feb96982830d2d24368fd5e5d4149a7 325 Gene3D G3DSA:3.40.47.10 1 160 8.3E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS10950 2feb96982830d2d24368fd5e5d4149a7 325 SUPERFAMILY SSF53901 4 324 1.24E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS10950 2feb96982830d2d24368fd5e5d4149a7 325 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 184 3.0E-28 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWM22_RS10950 2feb96982830d2d24368fd5e5d4149a7 325 Gene3D G3DSA:3.40.47.10 161 325 3.3E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS10950 2feb96982830d2d24368fd5e5d4149a7 325 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 324 3.2E-104 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWM22_RS10950 2feb96982830d2d24368fd5e5d4149a7 325 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 234 324 9.1E-33 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWM22_RS10950 2feb96982830d2d24368fd5e5d4149a7 325 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 325 68.571 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 Gene3D G3DSA:2.60.410.10 296 393 4.3E-13 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 Gene3D G3DSA:3.40.710.10 22 294 8.0E-42 T 28-03-2018 CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 139 152 9.7E-11 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 56 67 9.7E-11 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 112 129 9.7E-11 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 SMART SM00936 294 394 1.8E-18 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 SUPERFAMILY SSF69189 286 405 4.32E-16 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 SUPERFAMILY SSF56601 3 294 1.22E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 23 270 1.7E-73 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CWM22_RS11375 c97d539a8afadc751bd91429551027af 413 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 294 393 2.5E-12 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWM22_RS08525 2454b32c0a86ae5790a0683975791638 92 Gene3D G3DSA:1.10.10.60 22 84 2.9E-5 T 28-03-2018 CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 SUPERFAMILY SSF52540 310 532 1.43E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 ProSitePatterns PS00211 ABC transporters family signature. 444 458 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 Pfam PF12848 ABC transporter 231 312 2.7E-25 T 28-03-2018 IPR032781 ABC-transporter extension domain CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 Gene3D G3DSA:3.40.50.300 2 291 4.6E-49 T 28-03-2018 CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 Gene3D G3DSA:3.40.50.300 292 543 5.2E-49 T 28-03-2018 CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 SMART SM00382 28 247 2.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 SMART SM00382 351 526 3.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 Gene3D G3DSA:1.20.5.1070 544 632 7.9E-4 T 28-03-2018 CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 Pfam PF00005 ABC transporter 20 191 1.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 Pfam PF00005 ABC transporter 346 472 3.6E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 SUPERFAMILY SSF52540 5 94 3.34E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 SUPERFAMILY SSF52540 132 265 3.34E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04530 6ff61b98ade7bc61ab65af5679150701 632 Pfam PF16326 ABC transporter C-terminal domain 564 629 8.4E-10 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 Gene3D G3DSA:3.40.50.720 2 276 1.9E-56 T 28-03-2018 CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 165 3.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 3.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 213 3.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 236 256 3.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.4E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 162 190 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 4.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 194 4.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 163 4.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 274 1.2E-40 T 28-03-2018 CWM22_RS08095 54b66f72ee16f625c294f13356e9c564 279 SUPERFAMILY SSF51735 8 275 1.8E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS10460 333baf495b38e82ccd449de299a8772f 605 Gene3D G3DSA:3.30.160.60 569 604 3.5E-11 T 28-03-2018 CWM22_RS10460 333baf495b38e82ccd449de299a8772f 605 Pfam PF02618 YceG-like family 276 596 8.1E-71 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CWM22_RS10460 333baf495b38e82ccd449de299a8772f 605 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 241 600 30.389 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CWM22_RS10460 333baf495b38e82ccd449de299a8772f 605 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 234 600 1.1E-72 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 2 255 4.7E-73 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 SUPERFAMILY SSF55347 119 227 1.55E-40 T 28-03-2018 CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 PIRSF PIRSF000161 1 255 1.9E-69 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 SUPERFAMILY SSF51735 2 145 1.12E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 Gene3D G3DSA:3.40.50.720 1 111 1.7E-26 T 28-03-2018 CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 Gene3D G3DSA:3.30.360.10 120 224 2.4E-36 T 28-03-2018 CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 118 8.1E-29 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 3 255 27.642 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 121 255 1.4E-31 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS06975 bbcc7142fc959bc69603fb463068d058 255 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 140 157 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWM22_RS13350 a7f5acf22f37c26be1aea247ffeaec77 427 Pfam PF05193 Peptidase M16 inactive domain 184 362 4.3E-15 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CWM22_RS13350 a7f5acf22f37c26be1aea247ffeaec77 427 SUPERFAMILY SSF63411 248 424 2.38E-17 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWM22_RS13350 a7f5acf22f37c26be1aea247ffeaec77 427 Pfam PF00675 Insulinase (Peptidase family M16) 64 177 2.2E-19 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CWM22_RS13350 a7f5acf22f37c26be1aea247ffeaec77 427 Gene3D G3DSA:3.30.830.10 224 424 8.3E-15 T 28-03-2018 CWM22_RS13350 a7f5acf22f37c26be1aea247ffeaec77 427 Gene3D G3DSA:3.30.830.10 3 223 1.6E-46 T 28-03-2018 CWM22_RS13350 a7f5acf22f37c26be1aea247ffeaec77 427 SUPERFAMILY SSF63411 15 222 1.04E-40 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWM22_RS09185 c2fb7ce2e1a35e6c5e12e69afca33ed7 497 Pfam PF08708 Primase C terminal 1 (PriCT-1) 267 323 1.3E-7 T 28-03-2018 IPR014820 Primase, C-terminal 1 CWM22_RS09185 c2fb7ce2e1a35e6c5e12e69afca33ed7 497 SMART SM00942 259 324 1.2E-5 T 28-03-2018 IPR014820 Primase, C-terminal 1 CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 379 387 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 SUPERFAMILY SSF51445 1 41 1.84E-164 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 SUPERFAMILY SSF51445 69 481 1.84E-164 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 Gene3D G3DSA:3.20.20.80 1 485 3.3E-153 T 28-03-2018 CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 Pfam PF00232 Glycosyl hydrolase family 1 2 481 3.3E-135 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 313 327 2.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 379 387 2.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 400 411 2.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 446 458 2.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS11105 ff03c30d1924379214208d356148c5b2 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 421 438 2.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS04505 66dc2155a382c061b8b38a50cb91bc42 316 Gene3D G3DSA:1.10.10.60 241 308 1.4E-4 T 28-03-2018 CWM22_RS04505 66dc2155a382c061b8b38a50cb91bc42 316 Pfam PF12784 PD-(D/E)XK nuclease family transposase 11 232 5.3E-16 T 28-03-2018 CWM22_RS04505 66dc2155a382c061b8b38a50cb91bc42 316 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 308 6.8E-22 T 28-03-2018 IPR010106 Recombination-promoting nuclease RpnA CWM22_RS04480 06a173478b1ac8f05754440be712d92e 500 Gene3D G3DSA:3.40.50.2000 318 489 8.6E-27 T 28-03-2018 CWM22_RS04480 06a173478b1ac8f05754440be712d92e 500 Pfam PF00534 Glycosyl transferases group 1 314 457 1.1E-23 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWM22_RS04480 06a173478b1ac8f05754440be712d92e 500 SUPERFAMILY SSF53756 143 498 1.57E-35 T 28-03-2018 CWM22_RS04480 06a173478b1ac8f05754440be712d92e 500 Hamap MF_01472 Glycosyltransferase Gtf1 [gtf1]. 2 500 48.242 T 28-03-2018 IPR014267 Glycosyltransferase Gtf1 GO:0016757 CWM22_RS04480 06a173478b1ac8f05754440be712d92e 500 TIGRFAM TIGR02918 TIGR02918: accessory Sec system glycosylation protein GtfA 1 498 1.3E-233 T 28-03-2018 IPR014267 Glycosyltransferase Gtf1 GO:0016757 CWM22_RS06065 d1902af8355d78b9e014b88d11034239 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 1.8E-45 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS06065 d1902af8355d78b9e014b88d11034239 121 SUPERFAMILY SSF54736 51 121 6.8E-24 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CWM22_RS06065 d1902af8355d78b9e014b88d11034239 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 4.6E-19 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS06065 d1902af8355d78b9e014b88d11034239 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 2.5E-30 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS06065 d1902af8355d78b9e014b88d11034239 121 SUPERFAMILY SSF48300 3 51 3.92E-14 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS06065 d1902af8355d78b9e014b88d11034239 121 Gene3D G3DSA:3.30.1390.10 51 121 5.6E-29 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CWM22_RS06065 d1902af8355d78b9e014b88d11034239 121 Gene3D G3DSA:1.20.5.710 3 50 9.8E-15 T 28-03-2018 CWM22_RS06065 d1902af8355d78b9e014b88d11034239 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 24.455 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS06065 d1902af8355d78b9e014b88d11034239 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 2.0E-17 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS12295 47b2d78f18da74632906feeb1228069f 287 TIGRFAM TIGR01076 sortase_fam: sortase 109 242 3.0E-55 T 28-03-2018 IPR005754 Sortase family CWM22_RS12295 47b2d78f18da74632906feeb1228069f 287 Pfam PF04203 Sortase family 111 236 7.4E-22 T 28-03-2018 IPR005754 Sortase family CWM22_RS12295 47b2d78f18da74632906feeb1228069f 287 Gene3D G3DSA:2.40.260.10 44 249 4.9E-51 T 28-03-2018 IPR023365 Sortase domain CWM22_RS12295 47b2d78f18da74632906feeb1228069f 287 SUPERFAMILY SSF63817 96 240 3.01E-44 T 28-03-2018 IPR023365 Sortase domain CWM22_RS09355 83b3c80ebcc20036b8f51450ae846206 323 Gene3D G3DSA:3.40.50.1820 1 322 6.2E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS09355 83b3c80ebcc20036b8f51450ae846206 323 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 32 211 7.6E-9 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CWM22_RS09355 83b3c80ebcc20036b8f51450ae846206 323 SUPERFAMILY SSF53474 251 322 3.11E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS09355 83b3c80ebcc20036b8f51450ae846206 323 SUPERFAMILY SSF53474 6 218 3.11E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS12140 59c4b86890334236160b416bec6d576a 429 Gene3D G3DSA:3.90.350.10 123 335 4.4E-25 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS12140 59c4b86890334236160b416bec6d576a 429 SUPERFAMILY SSF53098 99 395 9.1E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS12140 59c4b86890334236160b416bec6d576a 429 Pfam PF01609 Transposase DDE domain 100 351 2.8E-28 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS01875 8e82339327c9c30047b6b075c70101cd 166 Pfam PF11193 Protein of unknown function (DUF2812) 15 118 1.9E-30 T 28-03-2018 IPR021359 Protein of unknown function DUF2812 CWM22_RS09635 81c17aafbc81024c4291ea617b0cef12 131 Pfam PF09355 Phage protein Gp19/Gp15/Gp42 13 128 7.1E-49 T 28-03-2018 IPR018963 Mycobacteriophage D29, Gp19 CWM22_RS01710 5d420e3ad09d72ad8389c8a9db28d59e 249 Gene3D G3DSA:3.40.50.300 3 244 2.0E-55 T 28-03-2018 CWM22_RS01710 5d420e3ad09d72ad8389c8a9db28d59e 249 SMART SM00382 36 221 2.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS01710 5d420e3ad09d72ad8389c8a9db28d59e 249 SUPERFAMILY SSF52540 4 227 1.52E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01710 5d420e3ad09d72ad8389c8a9db28d59e 249 Pfam PF00005 ABC transporter 27 173 1.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS01710 5d420e3ad09d72ad8389c8a9db28d59e 249 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS08920 f86d43b7bc1f8f3f0f77770b51406ea0 253 PIRSF PIRSF039085 1 245 1.1E-101 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CWM22_RS08920 f86d43b7bc1f8f3f0f77770b51406ea0 253 SMART SM00382 28 216 2.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS08920 f86d43b7bc1f8f3f0f77770b51406ea0 253 SUPERFAMILY SSF52540 3 239 4.21E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08920 f86d43b7bc1f8f3f0f77770b51406ea0 253 Pfam PF00005 ABC transporter 19 168 1.4E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS08920 f86d43b7bc1f8f3f0f77770b51406ea0 253 Gene3D G3DSA:3.40.50.300 1 252 9.6E-74 T 28-03-2018 CWM22_RS08920 f86d43b7bc1f8f3f0f77770b51406ea0 253 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS08430 99dbd421257b2d204f00d1b7fb5ba28a 600 Pfam PF08439 Oligopeptidase F 112 181 1.0E-19 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CWM22_RS08430 99dbd421257b2d204f00d1b7fb5ba28a 600 Gene3D G3DSA:1.10.1370.10 78 591 5.3E-44 T 28-03-2018 CWM22_RS08430 99dbd421257b2d204f00d1b7fb5ba28a 600 Pfam PF01432 Peptidase family M3 202 581 6.7E-82 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CWM22_RS08430 99dbd421257b2d204f00d1b7fb5ba28a 600 SUPERFAMILY SSF55486 53 596 5.21E-129 T 28-03-2018 CWM22_RS08430 99dbd421257b2d204f00d1b7fb5ba28a 600 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 5 592 7.2E-179 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CWM22_RS01275 bbe9ea72da54e2ab5b825501873e2db5 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS01275 bbe9ea72da54e2ab5b825501873e2db5 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 231 301 4.3E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS09335 bbe9ea72da54e2ab5b825501873e2db5 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS09335 bbe9ea72da54e2ab5b825501873e2db5 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 231 301 4.3E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS04740 bbe9ea72da54e2ab5b825501873e2db5 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS04740 bbe9ea72da54e2ab5b825501873e2db5 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 231 301 4.3E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 Gene3D G3DSA:1.10.10.60 246 304 5.5E-16 T 28-03-2018 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 SMART SM00342 207 290 5.4E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 274 1.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 290 1.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 Gene3D G3DSA:2.60.120.280 8 179 2.0E-18 T 28-03-2018 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 Pfam PF12833 Helix-turn-helix domain 213 292 1.5E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 Gene3D G3DSA:1.10.10.60 185 245 9.4E-16 T 28-03-2018 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 Pfam PF02311 AraC-like ligand binding domain 32 167 1.9E-18 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 SUPERFAMILY SSF51215 39 174 2.48E-14 T 28-03-2018 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 SUPERFAMILY SSF46689 243 297 3.27E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS11160 3f9beb9fdd884cb4fa3fddc81b200eef 304 SUPERFAMILY SSF46689 191 241 1.02E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 SMART SM00760 366 435 1.3E-39 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 SUPERFAMILY SSF52540 121 331 2.81E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 251 278 4.3E-47 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 416 435 4.3E-47 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 185 199 4.3E-47 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 217 231 4.3E-47 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 153 173 4.3E-47 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 457 30.124 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 456 3.3E-154 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 Gene3D G3DSA:3.40.50.300 117 284 1.0E-22 T 28-03-2018 CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 Pfam PF00308 Bacterial dnaA protein 121 335 1.3E-84 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 Gene3D G3DSA:1.10.1750.10 359 457 1.5E-32 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 367 435 3.8E-30 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 ProSitePatterns PS01008 DnaA protein signature. 416 435 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 SUPERFAMILY SSF48295 359 456 7.06E-33 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 SMART SM00382 152 283 5.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS00005 184dbefa25144337eadcbda9dcfb8387 457 Gene3D G3DSA:1.10.8.60 286 357 7.6E-19 T 28-03-2018 CWM22_RS02160 19225de892be86d86b79edebbfa35a6e 488 SUPERFAMILY SSF75304 1 481 1.02E-152 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWM22_RS02160 19225de892be86d86b79edebbfa35a6e 488 ProSitePatterns PS00571 Amidases signature. 150 181 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CWM22_RS02160 19225de892be86d86b79edebbfa35a6e 488 Gene3D G3DSA:3.90.1300.10 1 483 3.9E-157 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWM22_RS02160 19225de892be86d86b79edebbfa35a6e 488 Pfam PF01425 Amidase 24 463 5.7E-146 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWM22_RS02160 19225de892be86d86b79edebbfa35a6e 488 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 475 4.3E-185 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWM22_RS02160 19225de892be86d86b79edebbfa35a6e 488 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 475 88.954 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWM22_RS05050 3f2404399dc2924cf3a2562fce7ac68d 267 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05050 3f2404399dc2924cf3a2562fce7ac68d 267 Pfam PF00005 ABC transporter 37 191 2.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05050 3f2404399dc2924cf3a2562fce7ac68d 267 SUPERFAMILY SSF52540 16 254 1.05E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05050 3f2404399dc2924cf3a2562fce7ac68d 267 Gene3D G3DSA:3.40.50.300 16 263 4.2E-56 T 28-03-2018 CWM22_RS05050 3f2404399dc2924cf3a2562fce7ac68d 267 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 21 267 1.1E-120 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CWM22_RS05050 3f2404399dc2924cf3a2562fce7ac68d 267 SMART SM00382 45 248 1.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11290 839fc4d2df3177f4c9d83d8943bd9f38 211 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 27 208 6.9E-57 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CWM22_RS11290 839fc4d2df3177f4c9d83d8943bd9f38 211 SUPERFAMILY SSF53335 8 207 7.36E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS11290 839fc4d2df3177f4c9d83d8943bd9f38 211 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 211 28.394 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CWM22_RS11290 839fc4d2df3177f4c9d83d8943bd9f38 211 Gene3D G3DSA:3.40.50.150 1 211 2.8E-34 T 28-03-2018 CWM22_RS11290 839fc4d2df3177f4c9d83d8943bd9f38 211 Pfam PF02390 Putative methyltransferase 38 206 5.7E-47 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CWM22_RS01770 4427e66de2d46992d9165f440224dbf4 494 TIGRFAM TIGR00260 thrC: threonine synthase 83 442 1.3E-70 T 28-03-2018 IPR004450 Threonine synthase-like CWM22_RS01770 4427e66de2d46992d9165f440224dbf4 494 Gene3D G3DSA:3.40.50.1100 208 443 3.9E-77 T 28-03-2018 CWM22_RS01770 4427e66de2d46992d9165f440224dbf4 494 SUPERFAMILY SSF53686 3 490 3.18E-146 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWM22_RS01770 4427e66de2d46992d9165f440224dbf4 494 Gene3D G3DSA:3.40.50.1100 107 207 1.1E-18 T 28-03-2018 CWM22_RS01770 4427e66de2d46992d9165f440224dbf4 494 Gene3D G3DSA:3.90.1380.10 2 88 5.8E-24 T 28-03-2018 IPR029144 Threonine synthase, N-terminal CWM22_RS01770 4427e66de2d46992d9165f440224dbf4 494 Pfam PF14821 Threonine synthase N terminus 5 80 2.9E-21 T 28-03-2018 IPR029144 Threonine synthase, N-terminal CWM22_RS02435 7e2b9bf85c80791444df35c988337933 111 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 1 104 23.803 T 28-03-2018 IPR011229 Cell cycle protein GpsB CWM22_RS02435 7e2b9bf85c80791444df35c988337933 111 Pfam PF05103 DivIVA protein 7 62 1.5E-13 T 28-03-2018 IPR007793 DivIVA family CWM22_RS02435 7e2b9bf85c80791444df35c988337933 111 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 7 39 9.6E-12 T 28-03-2018 IPR019933 DivIVA domain CWM22_RS02435 7e2b9bf85c80791444df35c988337933 111 PIRSF PIRSF029938 1 108 5.4E-37 T 28-03-2018 IPR011229 Cell cycle protein GpsB CWM22_RS05560 3f6947a7346f5b56e113f012b301425e 605 SUPERFAMILY SSF52540 139 561 4.35E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05560 3f6947a7346f5b56e113f012b301425e 605 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 123 555 7.2E-66 T 28-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 CWM22_RS05560 3f6947a7346f5b56e113f012b301425e 605 Gene3D G3DSA:3.40.50.300 79 566 5.5E-37 T 28-03-2018 CWM22_RS12280 9e20159af1812d5885dac0ff9a8e4cef 148 Gene3D G3DSA:2.40.50.40 39 106 2.9E-13 T 28-03-2018 CWM22_RS12280 9e20159af1812d5885dac0ff9a8e4cef 148 Pfam PF04397 LytTr DNA-binding domain 51 144 5.2E-22 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWM22_RS12280 9e20159af1812d5885dac0ff9a8e4cef 148 SMART SM00850 48 145 8.3E-27 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWM22_RS01660 06753f44fb3e91df125f811b4fc9ab22 297 SUPERFAMILY SSF74650 2 289 1.38E-47 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWM22_RS01660 06753f44fb3e91df125f811b4fc9ab22 297 Pfam PF01263 Aldose 1-epimerase 2 264 5.2E-34 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CWM22_RS01660 06753f44fb3e91df125f811b4fc9ab22 297 Gene3D G3DSA:2.70.98.10 1 293 2.3E-51 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CWM22_RS08600 ae9f29062c9f84a664e3671334014ecf 288 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 6 213 4.1E-63 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWM22_RS08600 ae9f29062c9f84a664e3671334014ecf 288 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 219 273 4.7E-22 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CWM22_RS08600 ae9f29062c9f84a664e3671334014ecf 288 PIRSF PIRSF006483 1 280 1.9E-86 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWM22_RS05310 f280474c56d3570adbdd4e6c0028d4d7 226 SUPERFAMILY SSF47781 19 92 6.67E-7 T 28-03-2018 IPR010994 RuvA domain 2-like CWM22_RS05310 f280474c56d3570adbdd4e6c0028d4d7 226 Gene3D G3DSA:3.40.140.10 100 225 2.7E-41 T 28-03-2018 CWM22_RS05310 f280474c56d3570adbdd4e6c0028d4d7 226 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CWM22_RS05310 f280474c56d3570adbdd4e6c0028d4d7 226 Gene3D G3DSA:1.10.150.20 38 88 1.9E-6 T 28-03-2018 CWM22_RS05310 f280474c56d3570adbdd4e6c0028d4d7 226 Pfam PF04002 RadC-like JAB domain 108 222 4.4E-40 T 28-03-2018 IPR025657 RadC-like JAB domain CWM22_RS05310 f280474c56d3570adbdd4e6c0028d4d7 226 TIGRFAM TIGR00608 radc: DNA repair protein RadC 13 224 6.8E-72 T 28-03-2018 IPR001405 RadC protein CWM22_RS02630 9c2d6ceba1c2471a2b9aa336103d71dd 450 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 89 450 1.9E-21 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CWM22_RS02630 9c2d6ceba1c2471a2b9aa336103d71dd 450 Pfam PF01938 TRAM domain 4 59 5.9E-7 T 28-03-2018 IPR002792 TRAM domain CWM22_RS02630 9c2d6ceba1c2471a2b9aa336103d71dd 450 SUPERFAMILY SSF53335 68 449 1.63E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02630 9c2d6ceba1c2471a2b9aa336103d71dd 450 SUPERFAMILY SSF50249 3 60 2.46E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS02630 9c2d6ceba1c2471a2b9aa336103d71dd 450 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 442 7.2E-135 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CWM22_RS02630 9c2d6ceba1c2471a2b9aa336103d71dd 450 Gene3D G3DSA:2.40.50.140 1 74 7.7E-19 T 28-03-2018 CWM22_RS02630 9c2d6ceba1c2471a2b9aa336103d71dd 450 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 381 412 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CWM22_RS02630 9c2d6ceba1c2471a2b9aa336103d71dd 450 Gene3D G3DSA:3.40.50.150 75 448 1.0E-54 T 28-03-2018 CWM22_RS02630 9c2d6ceba1c2471a2b9aa336103d71dd 450 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 432 442 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CWM22_RS05045 dd5d7ca67148b91d6c6c4394ca306a37 295 Gene3D G3DSA:1.10.3720.10 56 290 1.3E-38 T 28-03-2018 CWM22_RS05045 dd5d7ca67148b91d6c6c4394ca306a37 295 SUPERFAMILY SSF161098 17 278 1.83E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS05045 dd5d7ca67148b91d6c6c4394ca306a37 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 291 5.5E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS05045 dd5d7ca67148b91d6c6c4394ca306a37 295 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 287 5.7E-79 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CWM22_RS01960 7413a8c76c6a4a4ce0cbbb89599a7f31 188 PIRSF PIRSF007510 1 182 1.7E-86 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWM22_RS01960 7413a8c76c6a4a4ce0cbbb89599a7f31 188 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 25 186 5.0E-85 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWM22_RS01960 7413a8c76c6a4a4ce0cbbb89599a7f31 188 Pfam PF04260 Protein of unknown function (DUF436) 9 179 1.9E-74 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWM22_RS01960 7413a8c76c6a4a4ce0cbbb89599a7f31 188 Gene3D G3DSA:3.40.50.10360 5 181 6.2E-79 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWM22_RS01960 7413a8c76c6a4a4ce0cbbb89599a7f31 188 Hamap MF_00800 UPF0340 protein . 1 188 99.233 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWM22_RS01960 7413a8c76c6a4a4ce0cbbb89599a7f31 188 SUPERFAMILY SSF110710 4 186 3.66E-80 T 28-03-2018 CWM22_RS01960 7413a8c76c6a4a4ce0cbbb89599a7f31 188 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 8 179 7.2E-83 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 SUPERFAMILY SSF47917 351 467 2.04E-50 T 28-03-2018 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 SUPERFAMILY SSF52540 81 352 6.95E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 Gene3D G3DSA:1.10.1140.10 354 464 9.0E-40 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 SUPERFAMILY SSF50615 2 79 4.71E-24 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 5.1E-253 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 SMART SM00382 147 332 2.0E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 57.186 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 Gene3D G3DSA:3.40.50.300 80 353 2.8E-91 T 28-03-2018 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 Gene3D G3DSA:2.40.10.170 1 79 1.9E-30 T 28-03-2018 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 348 2.1E-67 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWM22_RS08160 11447e172374d72894e816fbdb1ffd18 468 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 77 5.4E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWM22_RS10815 23d1cba088e4cbedfa682c9780f75a18 330 Pfam PF03610 PTS system fructose IIA component 4 122 1.2E-33 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWM22_RS10815 23d1cba088e4cbedfa682c9780f75a18 330 Gene3D G3DSA:3.40.35.10 169 325 3.1E-54 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWM22_RS10815 23d1cba088e4cbedfa682c9780f75a18 330 Pfam PF03830 PTS system sorbose subfamily IIB component 170 316 6.7E-50 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWM22_RS10815 23d1cba088e4cbedfa682c9780f75a18 330 SUPERFAMILY SSF53062 1 137 3.27E-36 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWM22_RS10815 23d1cba088e4cbedfa682c9780f75a18 330 SUPERFAMILY SSF52728 169 328 3.01E-53 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWM22_RS10815 23d1cba088e4cbedfa682c9780f75a18 330 Gene3D G3DSA:3.40.50.510 1 147 1.8E-39 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 Pfam PF00682 HMGL-like 4 272 2.0E-98 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 SUPERFAMILY SSF51569 4 290 4.94E-94 T 28-03-2018 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 497 1.7E-27 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 SUPERFAMILY SSF110921 402 496 3.66E-15 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 Gene3D G3DSA:3.20.20.70 2 328 1.0E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 510 38.919 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 SMART SM00917 368 501 4.0E-25 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWM22_RS11815 f02658dddb6b409f419e338f46bd73f4 520 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 496 4.0E-186 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWM22_RS04370 85bbfc18087e768bf42d036e7e53d578 553 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 4 550 2.1E-149 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CWM22_RS04370 85bbfc18087e768bf42d036e7e53d578 553 SMART SM00849 16 206 1.8E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS04370 85bbfc18087e768bf42d036e7e53d578 553 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 359 402 1.3E-9 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CWM22_RS04370 85bbfc18087e768bf42d036e7e53d578 553 SUPERFAMILY SSF56281 4 419 2.15E-69 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS04370 85bbfc18087e768bf42d036e7e53d578 553 Gene3D G3DSA:3.60.15.10 1 445 1.3E-55 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS04370 85bbfc18087e768bf42d036e7e53d578 553 Hamap MF_01491 Ribonuclease J [rnj]. 1 552 38.444 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CWM22_RS04370 85bbfc18087e768bf42d036e7e53d578 553 Pfam PF00753 Metallo-beta-lactamase superfamily 18 165 1.1E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS06835 16a1d96b2ed58a471433765cbea32c0b 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS06835 16a1d96b2ed58a471433765cbea32c0b 450 Pfam PF03050 Transposase IS66 family 117 393 1.2E-82 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS06835 16a1d96b2ed58a471433765cbea32c0b 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS13355 39aa2cedb11c4595dffeffc1fe5aa480 417 SUPERFAMILY SSF63411 2 216 3.49E-16 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWM22_RS13355 39aa2cedb11c4595dffeffc1fe5aa480 417 Pfam PF05193 Peptidase M16 inactive domain 180 351 1.1E-21 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CWM22_RS13355 39aa2cedb11c4595dffeffc1fe5aa480 417 SUPERFAMILY SSF63411 235 402 2.67E-28 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWM22_RS13355 39aa2cedb11c4595dffeffc1fe5aa480 417 Gene3D G3DSA:3.30.830.10 11 216 3.2E-12 T 28-03-2018 CWM22_RS13355 39aa2cedb11c4595dffeffc1fe5aa480 417 Gene3D G3DSA:3.30.830.10 234 404 2.8E-27 T 28-03-2018 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 2.2E-75 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 Pfam PF01479 S4 domain 93 140 8.3E-22 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 Gene3D G3DSA:1.10.1050.10 143 201 1.9E-11 T 28-03-2018 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 92 1.3E-25 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 34.877 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 SMART SM00363 93 157 4.7E-21 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 ProSitePatterns PS00632 Ribosomal protein S4 signature. 91 115 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 SMART SM01390 3 92 1.4E-37 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 Gene3D G3DSA:1.10.1050.10 1 98 1.1E-36 T 28-03-2018 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 SUPERFAMILY SSF55174 3 201 1.05E-66 T 28-03-2018 CWM22_RS13215 5256305654523830fd86492f33c091fd 203 Gene3D G3DSA:3.10.290.10 99 142 1.7E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 PIRSF PIRSF000429 1 392 2.5E-125 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 Pfam PF00108 Thiolase, N-terminal domain 4 260 3.9E-96 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 SUPERFAMILY SSF53901 4 268 6.26E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 Gene3D G3DSA:3.40.47.10 264 388 1.7E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 SUPERFAMILY SSF53901 269 388 5.76E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 Pfam PF02803 Thiolase, C-terminal domain 269 389 5.8E-48 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 Gene3D G3DSA:3.40.47.10 1 263 8.8E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CWM22_RS03015 2c3543e01ab5424a3086b65fd98420b9 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 388 7.3E-143 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWM22_RS05945 a37d98dc636fe970dc8a5c7a41e28ae9 371 SUPERFAMILY SSF51161 229 348 8.87E-14 T 28-03-2018 IPR011004 Trimeric LpxA-like CWM22_RS05945 a37d98dc636fe970dc8a5c7a41e28ae9 371 Gene3D G3DSA:2.160.10.10 264 351 1.6E-11 T 28-03-2018 CWM22_RS05945 a37d98dc636fe970dc8a5c7a41e28ae9 371 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 4 366 4.8E-91 T 28-03-2018 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 CWM22_RS05945 a37d98dc636fe970dc8a5c7a41e28ae9 371 Gene3D G3DSA:3.90.550.10 17 263 1.4E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05945 a37d98dc636fe970dc8a5c7a41e28ae9 371 SUPERFAMILY SSF53448 320 325 4.64E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05945 a37d98dc636fe970dc8a5c7a41e28ae9 371 SUPERFAMILY SSF53448 28 259 4.64E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05945 a37d98dc636fe970dc8a5c7a41e28ae9 371 Pfam PF00483 Nucleotidyl transferase 28 228 1.1E-12 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWM22_RS09800 8878243eff2c94c599554c58080e53b0 266 Pfam PF07261 Replication initiation and membrane attachment 169 240 3.9E-19 T 28-03-2018 IPR006343 DnaD domain CWM22_RS09800 8878243eff2c94c599554c58080e53b0 266 Pfam PF09681 N-terminal phage replisome organiser (Phage_rep_org_N) 10 125 2.7E-29 T 28-03-2018 IPR010056 Phage replisome organiser, N-terminal domain CWM22_RS09800 8878243eff2c94c599554c58080e53b0 266 TIGRFAM TIGR01714 phage_rep_org_N: phage replisome organizer, putative, N-terminal region 10 128 2.6E-44 T 28-03-2018 IPR010056 Phage replisome organiser, N-terminal domain CWM22_RS09800 8878243eff2c94c599554c58080e53b0 266 SUPERFAMILY SSF158499 168 234 1.83E-15 T 28-03-2018 IPR006343 DnaD domain CWM22_RS09800 8878243eff2c94c599554c58080e53b0 266 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 168 240 5.3E-22 T 28-03-2018 IPR006343 DnaD domain CWM22_RS09800 8878243eff2c94c599554c58080e53b0 266 Gene3D G3DSA:1.10.10.630 163 239 9.8E-22 T 28-03-2018 IPR034829 DnaD-like domain CWM22_RS08985 7304e409c5671c4ca8eff9b4fdfd36a9 445 Gene3D G3DSA:3.90.1720.10 221 432 9.9E-4 T 28-03-2018 CWM22_RS08985 7304e409c5671c4ca8eff9b4fdfd36a9 445 SUPERFAMILY SSF54001 281 421 8.24E-11 T 28-03-2018 CWM22_RS08985 7304e409c5671c4ca8eff9b4fdfd36a9 445 Gene3D G3DSA:1.10.530.10 57 220 1.8E-13 T 28-03-2018 CWM22_RS08985 7304e409c5671c4ca8eff9b4fdfd36a9 445 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 72 217 4.8E-7 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWM22_RS08985 7304e409c5671c4ca8eff9b4fdfd36a9 445 Pfam PF05257 CHAP domain 321 401 4.7E-11 T 28-03-2018 IPR007921 CHAP domain CWM22_RS10115 982f1795db997038b0dd48baa20b812e 428 Pfam PF16325 Peptidase family U32 C-terminal domain 326 407 3.1E-21 T 28-03-2018 IPR032525 Peptidase family U32, C-terminal CWM22_RS10115 982f1795db997038b0dd48baa20b812e 428 ProSitePatterns PS01276 Peptidase family U32 signature. 165 183 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWM22_RS10115 982f1795db997038b0dd48baa20b812e 428 Gene3D G3DSA:3.20.20.70 9 288 7.7E-8 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS10115 982f1795db997038b0dd48baa20b812e 428 Pfam PF01136 Peptidase family U32 84 311 9.0E-87 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWM22_RS05185 93f11c040b59237094453d74be273b12 416 SUPERFAMILY SSF53383 16 415 7.21E-90 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS05185 93f11c040b59237094453d74be273b12 416 PIRSF PIRSF000390 12 416 1.4E-91 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CWM22_RS05185 93f11c040b59237094453d74be273b12 416 Gene3D G3DSA:3.40.640.10 23 243 1.0E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS05185 93f11c040b59237094453d74be273b12 416 Gene3D G3DSA:3.90.1150.10 258 416 5.9E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS05185 93f11c040b59237094453d74be273b12 416 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 26 412 1.2E-81 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CWM22_RS02720 f02e1b264d299cf0ccf45f66b64891ea 268 SUPERFAMILY SSF140931 81 253 5.49E-23 T 28-03-2018 IPR003812 Fido domain CWM22_RS02720 f02e1b264d299cf0ccf45f66b64891ea 268 Pfam PF02661 Fic/DOC family 92 200 1.2E-11 T 28-03-2018 IPR003812 Fido domain CWM22_RS02720 f02e1b264d299cf0ccf45f66b64891ea 268 Gene3D G3DSA:1.10.3290.10 3 258 5.4E-19 T 28-03-2018 IPR003812 Fido domain CWM22_RS07920 db8c4a22f96b381428005147a3aa7296 227 SUPERFAMILY SSF53335 8 140 3.1E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS07920 db8c4a22f96b381428005147a3aa7296 227 PIRSF PIRSF018637 3 227 9.2E-74 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CWM22_RS07920 db8c4a22f96b381428005147a3aa7296 227 Gene3D G3DSA:3.40.50.150 1 166 4.2E-18 T 28-03-2018 CWM22_RS07920 db8c4a22f96b381428005147a3aa7296 227 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 22 222 1.8E-74 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CWM22_RS07025 78b5dc9fbf1c2504d6b9d87144676d45 126 Pfam PF17225 Domain of unknown function (DUF5300) 25 112 6.8E-11 T 28-03-2018 IPR033782 Domain of unknown function DUF5301 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 SMART SM00962 220 421 5.4E-110 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 SUPERFAMILY SSF47364 120 198 8.64E-18 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 147 421 61.236 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 SMART SM00963 123 204 2.6E-20 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 SUPERFAMILY SSF52540 221 420 4.97E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 148 420 2.8E-107 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 Pfam PF02881 SRP54-type protein, helical bundle domain 134 200 8.9E-12 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 Gene3D G3DSA:1.20.120.140 120 217 1.1E-18 T 28-03-2018 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 Gene3D G3DSA:3.40.50.300 219 422 7.1E-38 T 28-03-2018 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 394 407 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 SMART SM00382 219 397 6.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS08255 c850e20a75b372a93c7602c6427df1a1 424 Pfam PF00448 SRP54-type protein, GTPase domain 221 420 9.4E-75 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWM22_RS02995 3b006c72263d9811fcc278d0e318f0e5 155 Pfam PF00583 Acetyltransferase (GNAT) family 40 143 1.7E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS02995 3b006c72263d9811fcc278d0e318f0e5 155 SUPERFAMILY SSF55729 1 149 5.15E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS02995 3b006c72263d9811fcc278d0e318f0e5 155 Gene3D G3DSA:3.40.630.30 1 151 1.5E-30 T 28-03-2018 CWM22_RS01205 8edeeb44903f9a0b93685d230b0224b5 308 Pfam PF02779 Transketolase, pyrimidine binding domain 6 163 4.6E-23 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWM22_RS01205 8edeeb44903f9a0b93685d230b0224b5 308 SUPERFAMILY SSF52518 4 166 7.5E-40 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWM22_RS01205 8edeeb44903f9a0b93685d230b0224b5 308 SUPERFAMILY SSF52922 182 306 3.53E-27 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWM22_RS01205 8edeeb44903f9a0b93685d230b0224b5 308 Gene3D G3DSA:3.40.50.920 181 308 7.1E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWM22_RS01205 8edeeb44903f9a0b93685d230b0224b5 308 Gene3D G3DSA:3.40.50.970 2 180 1.4E-31 T 28-03-2018 CWM22_RS01205 8edeeb44903f9a0b93685d230b0224b5 308 Pfam PF02780 Transketolase, C-terminal domain 184 298 6.7E-25 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CWM22_RS01205 8edeeb44903f9a0b93685d230b0224b5 308 SMART SM00861 5 171 3.4E-25 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWM22_RS03830 ef57a4af1afdcad035e31f0e453a4b18 309 Gene3D G3DSA:3.40.50.1980 42 142 1.1E-15 T 28-03-2018 CWM22_RS03830 ef57a4af1afdcad035e31f0e453a4b18 309 Pfam PF01497 Periplasmic binding protein 56 282 1.6E-33 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CWM22_RS03830 ef57a4af1afdcad035e31f0e453a4b18 309 SUPERFAMILY SSF53807 46 296 1.22E-50 T 28-03-2018 CWM22_RS03830 ef57a4af1afdcad035e31f0e453a4b18 309 Gene3D G3DSA:3.40.50.1980 143 309 5.4E-33 T 28-03-2018 CWM22_RS03785 8b845651e9470d1aa393cfad670b50d3 79 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 77 50.069 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CWM22_RS03785 8b845651e9470d1aa393cfad670b50d3 79 Gene3D G3DSA:1.10.1200.10 1 79 3.9E-12 T 28-03-2018 CWM22_RS03785 8b845651e9470d1aa393cfad670b50d3 79 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 4 73 3.8E-22 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CWM22_RS03785 8b845651e9470d1aa393cfad670b50d3 79 Pfam PF00550 Phosphopantetheine attachment site 6 69 8.6E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWM22_RS03785 8b845651e9470d1aa393cfad670b50d3 79 SUPERFAMILY SSF47336 3 77 4.58E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWM22_RS12270 70478aff5393214ed8836fca504216cb 426 Pfam PF07690 Major Facilitator Superfamily 131 378 5.8E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWM22_RS12270 70478aff5393214ed8836fca504216cb 426 SUPERFAMILY SSF103473 9 418 4.19E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWM22_RS12270 70478aff5393214ed8836fca504216cb 426 Gene3D G3DSA:1.20.1250.20 1 200 7.5E-12 T 28-03-2018 CWM22_RS12270 70478aff5393214ed8836fca504216cb 426 Gene3D G3DSA:1.20.1250.20 221 420 7.5E-8 T 28-03-2018 CWM22_RS03115 3beb460838dc9d103d3964bbe903543e 190 SUPERFAMILY SSF55729 11 176 2.66E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS03115 3beb460838dc9d103d3964bbe903543e 190 Pfam PF13302 Acetyltransferase (GNAT) domain 17 152 5.4E-24 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS03115 3beb460838dc9d103d3964bbe903543e 190 Gene3D G3DSA:3.40.630.30 5 184 1.6E-21 T 28-03-2018 CWM22_RS12075 58757c8384f27270b7853ae091bfb9d0 313 SUPERFAMILY SSF109604 146 281 1.1E-10 T 28-03-2018 CWM22_RS12075 58757c8384f27270b7853ae091bfb9d0 313 Gene3D G3DSA:2.40.50.140 1 90 1.5E-7 T 28-03-2018 CWM22_RS12075 58757c8384f27270b7853ae091bfb9d0 313 Pfam PF01966 HD domain 161 278 1.7E-6 T 28-03-2018 IPR006674 HD domain CWM22_RS12075 58757c8384f27270b7853ae091bfb9d0 313 Gene3D G3DSA:1.10.3210.10 143 305 4.2E-12 T 28-03-2018 CWM22_RS09345 0a3da21c6d01d6430251beff9fe0a381 161 SUPERFAMILY SSF52833 2 158 1.49E-40 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS09345 0a3da21c6d01d6430251beff9fe0a381 161 ProSitePatterns PS01265 Tpx family signature. 81 92 - T 28-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CWM22_RS09345 0a3da21c6d01d6430251beff9fe0a381 161 Gene3D G3DSA:3.40.30.10 9 161 3.3E-20 T 28-03-2018 CWM22_RS09345 0a3da21c6d01d6430251beff9fe0a381 161 Hamap MF_00269 Probable thiol peroxidase [tpx]. 1 161 35.908 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CWM22_RS09345 0a3da21c6d01d6430251beff9fe0a381 161 Pfam PF08534 Redoxin 18 157 1.5E-23 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CWM22_RS02795 553416961924c49f6ba97326ae83ed60 360 Pfam PF08478 POTRA domain, FtsQ-type 163 233 1.1E-12 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CWM22_RS02795 553416961924c49f6ba97326ae83ed60 360 Hamap MF_00912 Cell division protein DivIB [divIB]. 80 360 31.161 T 28-03-2018 IPR026580 Cell division protein DivIB CWM22_RS01635 4ad92c55b6d7e829eb10041f3d3df033 325 Gene3D G3DSA:3.20.20.70 4 325 1.9E-78 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS01635 4ad92c55b6d7e829eb10041f3d3df033 325 TIGRFAM TIGR01232 lacD: tagatose 1,6-diphosphate aldolase 3 325 8.7E-175 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWM22_RS01635 4ad92c55b6d7e829eb10041f3d3df033 325 Hamap MF_00734 Tagatose 1,6-diphosphate aldolase [lacD]. 1 325 205.297 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWM22_RS01635 4ad92c55b6d7e829eb10041f3d3df033 325 SUPERFAMILY SSF51569 7 322 3.26E-67 T 28-03-2018 CWM22_RS01635 4ad92c55b6d7e829eb10041f3d3df033 325 Pfam PF01791 DeoC/LacD family aldolase 21 282 3.4E-74 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWM22_RS01635 4ad92c55b6d7e829eb10041f3d3df033 325 SMART SM01133 21 283 7.8E-26 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWM22_RS11015 1ab96227a7513bb00e40e7b95ebb1b31 139 Pfam PF01029 NusB family 8 136 8.5E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWM22_RS11015 1ab96227a7513bb00e40e7b95ebb1b31 139 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 3 139 21.608 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CWM22_RS11015 1ab96227a7513bb00e40e7b95ebb1b31 139 Gene3D G3DSA:1.10.940.10 1 139 5.4E-39 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWM22_RS11015 1ab96227a7513bb00e40e7b95ebb1b31 139 SUPERFAMILY SSF48013 5 134 1.7E-36 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWM22_RS11015 1ab96227a7513bb00e40e7b95ebb1b31 139 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 5 137 2.5E-38 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CWM22_RS01900 2bd40c592cbcb5d8212d9e107281cf5b 481 SUPERFAMILY SSF75304 3 387 8.37E-110 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWM22_RS01900 2bd40c592cbcb5d8212d9e107281cf5b 481 SUPERFAMILY SSF75304 420 476 8.37E-110 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWM22_RS01900 2bd40c592cbcb5d8212d9e107281cf5b 481 ProSitePatterns PS00571 Amidases signature. 144 175 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CWM22_RS01900 2bd40c592cbcb5d8212d9e107281cf5b 481 Gene3D G3DSA:3.90.1300.10 2 478 1.1E-110 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWM22_RS01900 2bd40c592cbcb5d8212d9e107281cf5b 481 Pfam PF01425 Amidase 21 467 1.2E-76 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 Gene3D G3DSA:3.40.50.150 1 251 7.7E-52 T 28-03-2018 CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 418 1.5E-67 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 SUPERFAMILY SSF53335 1 181 2.87E-68 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 SUPERFAMILY SSF53335 259 418 2.87E-68 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 74 86 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 Gene3D G3DSA:3.90.120.10 270 405 4.1E-19 T 28-03-2018 CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 7.7E-13 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 165 178 7.7E-13 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 116 130 7.7E-13 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS02745 7a75723961c98098fab5dff89bee547b 421 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 4 416 6.2E-65 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS07850 9fdd0f9cb041ad52d0fdaa7ae776c9c8 309 Gene3D G3DSA:3.90.550.10 1 293 6.3E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07850 9fdd0f9cb041ad52d0fdaa7ae776c9c8 309 SUPERFAMILY SSF53448 2 228 1.78E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07850 9fdd0f9cb041ad52d0fdaa7ae776c9c8 309 Pfam PF00535 Glycosyl transferase family 2 5 116 4.0E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS02855 052a66676851ce963f938d79221636f8 102 Pfam PF08860 Domain of unknown function (DUF1827) 1 97 1.2E-35 T 28-03-2018 IPR014959 Protein of unknown function DUF1827 CWM22_RS02855 052a66676851ce963f938d79221636f8 102 Gene3D G3DSA:3.40.1720.10 1 96 1.4E-38 T 28-03-2018 CWM22_RS05970 8064b0655debf1327af4e3aaf155c374 231 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 220 3.5E-48 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS05970 8064b0655debf1327af4e3aaf155c374 231 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 221 1.4E-63 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS05970 8064b0655debf1327af4e3aaf155c374 231 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 58 71 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS05970 8064b0655debf1327af4e3aaf155c374 231 SUPERFAMILY SSF51366 1 228 2.77E-73 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWM22_RS05970 8064b0655debf1327af4e3aaf155c374 231 Gene3D G3DSA:3.20.20.70 1 229 1.5E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS05970 8064b0655debf1327af4e3aaf155c374 231 SMART SM00934 5 224 2.1E-95 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS05970 8064b0655debf1327af4e3aaf155c374 231 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 229 40.134 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWM22_RS04690 bc88a7cfac6b796abfcd1ddae6c17b49 125 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 5 106 1.8E-12 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system CWM22_RS04690 bc88a7cfac6b796abfcd1ddae6c17b49 125 SUPERFAMILY SSF143100 2 65 7.85E-15 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like CWM22_RS04690 bc88a7cfac6b796abfcd1ddae6c17b49 125 Gene3D G3DSA:3.30.2390.10 3 68 4.3E-12 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like CWM22_RS06990 ffffe2c87f38a15fdcdf4f383a0d0504 1864 Pfam PF04650 YSIRK type signal peptide 5 27 2.3E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS06990 ffffe2c87f38a15fdcdf4f383a0d0504 1864 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 98 129 6.8E-5 T 28-03-2018 CWM22_RS06990 ffffe2c87f38a15fdcdf4f383a0d0504 1864 SUPERFAMILY SSF51126 870 1047 3.05E-5 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CWM22_RS06990 ffffe2c87f38a15fdcdf4f383a0d0504 1864 SUPERFAMILY SSF51126 709 838 3.05E-5 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CWM22_RS06990 ffffe2c87f38a15fdcdf4f383a0d0504 1864 Pfam PF05342 M26 IgA1-specific Metallo-endopeptidase N-terminal region 563 802 1.8E-47 T 28-03-2018 IPR008006 Peptidase M26, N-terminal domain GO:0004222|GO:0008270|GO:0016021 CWM22_RS06990 ffffe2c87f38a15fdcdf4f383a0d0504 1864 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 4 26 7.8E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS06990 ffffe2c87f38a15fdcdf4f383a0d0504 1864 Pfam PF07580 M26 IgA1-specific Metallo-endopeptidase C-terminal region 1104 1862 2.0E-156 T 28-03-2018 IPR011505 Peptidase M26, C-terminal domain GO:0004222|GO:0005576|GO:0005618|GO:0008270 CWM22_RS01140 af257a8f659e4a9565d289b9595d5f25 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 104 1.6E-22 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CWM22_RS04375 cc36a4c35411295441b8b82c8bad646b 258 Pfam PF00756 Putative esterase 10 246 2.4E-17 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CWM22_RS04375 cc36a4c35411295441b8b82c8bad646b 258 SUPERFAMILY SSF53474 2 247 4.61E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS04375 cc36a4c35411295441b8b82c8bad646b 258 Gene3D G3DSA:3.40.50.1820 1 258 1.1E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS07240 7ef2e5401e0bbb5479811927bd452128 380 Gene3D G3DSA:3.40.640.10 10 255 4.8E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS07240 7ef2e5401e0bbb5479811927bd452128 380 PIRSF PIRSF005572 1 380 1.7E-116 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWM22_RS07240 7ef2e5401e0bbb5479811927bd452128 380 Gene3D G3DSA:3.90.1150.10 263 380 1.5E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS07240 7ef2e5401e0bbb5479811927bd452128 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CWM22_RS07240 7ef2e5401e0bbb5479811927bd452128 380 SUPERFAMILY SSF53383 1 374 7.88E-94 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS07240 7ef2e5401e0bbb5479811927bd452128 380 Pfam PF00266 Aminotransferase class-V 2 365 3.7E-68 T 28-03-2018 IPR000192 Aminotransferase class V domain CWM22_RS06900 b89cf0e1eb11a1ed211b7e442f9b29eb 440 SMART SM00894 404 440 3.9E-20 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CWM22_RS06900 b89cf0e1eb11a1ed211b7e442f9b29eb 440 Gene3D G3DSA:3.40.50.150 175 250 0.1 T 28-03-2018 CWM22_RS06900 b89cf0e1eb11a1ed211b7e442f9b29eb 440 Pfam PF05901 Excalibur calcium-binding domain 405 440 3.5E-14 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CWM22_RS04915 ca77867407ca3add979cae030c4c8bce 252 Pfam PF06738 Putative threonine/serine exporter 12 250 9.1E-68 T 28-03-2018 IPR010619 Putative threonine/serine exporter CWM22_RS01670 bf4f25c73f9e3c195494cd0e5af9659d 421 Gene3D G3DSA:1.10.443.10 194 410 3.6E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS01670 bf4f25c73f9e3c195494cd0e5af9659d 421 Pfam PF00589 Phage integrase family 204 401 8.4E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS01670 bf4f25c73f9e3c195494cd0e5af9659d 421 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 80 137 3.0E-10 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWM22_RS01670 bf4f25c73f9e3c195494cd0e5af9659d 421 Gene3D G3DSA:1.10.150.130 70 193 3.1E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWM22_RS01670 bf4f25c73f9e3c195494cd0e5af9659d 421 SUPERFAMILY SSF56349 79 408 8.83E-54 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS08030 31d0dff923a25b3785e6eb0d16598f2d 187 Gene3D G3DSA:3.30.1130.10 54 187 5.6E-58 T 28-03-2018 CWM22_RS08030 31d0dff923a25b3785e6eb0d16598f2d 187 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 63 79 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWM22_RS08030 31d0dff923a25b3785e6eb0d16598f2d 187 SUPERFAMILY SSF55620 4 185 3.85E-76 T 28-03-2018 CWM22_RS08030 31d0dff923a25b3785e6eb0d16598f2d 187 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 112 122 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWM22_RS08030 31d0dff923a25b3785e6eb0d16598f2d 187 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 7 185 1.9E-75 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWM22_RS08030 31d0dff923a25b3785e6eb0d16598f2d 187 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 3 185 41.036 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWM22_RS08030 31d0dff923a25b3785e6eb0d16598f2d 187 Gene3D G3DSA:1.10.286.10 5 52 1.4E-21 T 28-03-2018 CWM22_RS08030 31d0dff923a25b3785e6eb0d16598f2d 187 Pfam PF01227 GTP cyclohydrolase I 7 184 6.1E-77 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWM22_RS07845 a82e78d2687af8bdd6093d58fe7ec3dc 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 7.4E-5 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWM22_RS07845 a82e78d2687af8bdd6093d58fe7ec3dc 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 31 52 7.4E-5 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWM22_RS07845 a82e78d2687af8bdd6093d58fe7ec3dc 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 62 84 7.4E-5 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWM22_RS07845 a82e78d2687af8bdd6093d58fe7ec3dc 268 Pfam PF01061 ABC-2 type transporter 12 218 2.6E-17 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CWM22_RS00845 3d7c43e7052e8eda1fe6a64524e1abc6 125 Pfam PF01230 HIT domain 11 100 5.3E-10 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CWM22_RS00845 3d7c43e7052e8eda1fe6a64524e1abc6 125 SUPERFAMILY SSF54197 1 106 1.7E-25 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CWM22_RS00845 3d7c43e7052e8eda1fe6a64524e1abc6 125 Gene3D G3DSA:3.30.428.10 1 113 2.4E-20 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CWM22_RS01510 45ab7139bd6da22c8f5caa3696609c65 312 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 307 28.026 T 28-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CWM22_RS01510 45ab7139bd6da22c8f5caa3696609c65 312 Gene3D G3DSA:3.20.20.70 2 310 3.0E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS01510 45ab7139bd6da22c8f5caa3696609c65 312 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 305 2.7E-52 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWM22_RS01510 45ab7139bd6da22c8f5caa3696609c65 312 PIRSF PIRSF000164 1 309 3.1E-64 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CWM22_RS01510 45ab7139bd6da22c8f5caa3696609c65 312 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CWM22_RS01510 45ab7139bd6da22c8f5caa3696609c65 312 SUPERFAMILY SSF51395 1 307 1.22E-68 T 28-03-2018 CWM22_RS01510 45ab7139bd6da22c8f5caa3696609c65 312 Pfam PF01180 Dihydroorotate dehydrogenase 5 292 2.0E-78 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWM22_RS01510 45ab7139bd6da22c8f5caa3696609c65 312 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 244 264 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CWM22_RS09390 3a03553f4cbd5b1e09ed4d68eccaf791 69 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 15 68 2.5E-14 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 CWM22_RS09390 3a03553f4cbd5b1e09ed4d68eccaf791 69 SUPERFAMILY SSF54786 10 68 5.89E-13 T 28-03-2018 CWM22_RS09390 3a03553f4cbd5b1e09ed4d68eccaf791 69 Gene3D G3DSA:3.30.920.30 6 68 3.3E-18 T 28-03-2018 CWM22_RS06695 cdb2d1b204e25a60f503f5a071aa819c 221 Pfam PF00072 Response regulator receiver domain 6 111 9.2E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS06695 cdb2d1b204e25a60f503f5a071aa819c 221 SUPERFAMILY SSF52172 1 177 1.76E-30 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS06695 cdb2d1b204e25a60f503f5a071aa819c 221 SMART SM00448 4 113 6.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS06695 cdb2d1b204e25a60f503f5a071aa819c 221 Gene3D G3DSA:3.40.50.2300 1 126 5.8E-27 T 28-03-2018 CWM22_RS06695 cdb2d1b204e25a60f503f5a071aa819c 221 Gene3D G3DSA:1.10.10.10 127 221 6.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS06695 cdb2d1b204e25a60f503f5a071aa819c 221 SMART SM00862 146 220 7.7E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS06695 cdb2d1b204e25a60f503f5a071aa819c 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 219 2.8E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS01825 9f27d3e470bceef51e8f4116352ae49f 341 PIRSF PIRSF015950 1 331 6.8E-115 T 28-03-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CWM22_RS01825 9f27d3e470bceef51e8f4116352ae49f 341 SUPERFAMILY SSF55060 176 320 7.05E-42 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS01825 9f27d3e470bceef51e8f4116352ae49f 341 SUPERFAMILY SSF54211 5 171 1.52E-38 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS01825 9f27d3e470bceef51e8f4116352ae49f 341 Pfam PF00288 GHMP kinases N terminal domain 98 136 7.0E-5 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWM22_RS01825 9f27d3e470bceef51e8f4116352ae49f 341 Gene3D G3DSA:3.30.70.890 174 339 1.4E-43 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS01825 9f27d3e470bceef51e8f4116352ae49f 341 Gene3D G3DSA:3.30.230.10 1 173 8.1E-55 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS01825 9f27d3e470bceef51e8f4116352ae49f 341 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 8 308 2.5E-113 T 28-03-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CWM22_RS08455 2a572fbc550ffe02aa11d26d35cd3700 1032 Pfam PF04851 Type III restriction enzyme, res subunit 91 256 1.2E-14 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS08455 2a572fbc550ffe02aa11d26d35cd3700 1032 Gene3D G3DSA:3.40.50.300 1 269 1.6E-21 T 28-03-2018 CWM22_RS08455 2a572fbc550ffe02aa11d26d35cd3700 1032 SUPERFAMILY SSF52540 93 270 9.61E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06970 32fbbe41e048b08e672969e8ec560732 403 Gene3D G3DSA:1.10.3090.10 147 399 3.4E-41 T 28-03-2018 CWM22_RS06970 32fbbe41e048b08e672969e8ec560732 403 Gene3D G3DSA:3.30.460.10 7 146 8.4E-47 T 28-03-2018 CWM22_RS06970 32fbbe41e048b08e672969e8ec560732 403 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 251 396 2.8E-46 T 28-03-2018 IPR032810 CCA-adding enzyme, C-terminal CWM22_RS06970 32fbbe41e048b08e672969e8ec560732 403 SUPERFAMILY SSF81301 10 144 1.09E-41 T 28-03-2018 CWM22_RS06970 32fbbe41e048b08e672969e8ec560732 403 SUPERFAMILY SSF81891 145 402 4.45E-56 T 28-03-2018 CWM22_RS06970 32fbbe41e048b08e672969e8ec560732 403 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 174 232 2.0E-16 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CWM22_RS06970 32fbbe41e048b08e672969e8ec560732 403 Pfam PF01743 Poly A polymerase head domain 27 147 8.2E-38 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CWM22_RS06970 32fbbe41e048b08e672969e8ec560732 403 Hamap MF_01263 CCA-adding enzyme [cca]. 7 400 41.674 T 28-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 CWM22_RS01775 a429f53bac47eda506b0b054e3de8b17 588 Pfam PF00664 ABC transporter transmembrane region 37 300 1.9E-15 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS01775 a429f53bac47eda506b0b054e3de8b17 588 SMART SM00382 371 556 2.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS01775 a429f53bac47eda506b0b054e3de8b17 588 SUPERFAMILY SSF90123 16 328 3.4E-37 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS01775 a429f53bac47eda506b0b054e3de8b17 588 Pfam PF00005 ABC transporter 362 510 2.5E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS01775 a429f53bac47eda506b0b054e3de8b17 588 Gene3D G3DSA:3.40.50.300 332 585 1.5E-48 T 28-03-2018 CWM22_RS01775 a429f53bac47eda506b0b054e3de8b17 588 Gene3D G3DSA:1.20.1560.10 10 330 8.8E-29 T 28-03-2018 CWM22_RS01775 a429f53bac47eda506b0b054e3de8b17 588 SUPERFAMILY SSF52540 342 579 5.75E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09435 7caf0281b05d0b15094c7410781685c1 200 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 198 27.054 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CWM22_RS09435 7caf0281b05d0b15094c7410781685c1 200 Gene3D G3DSA:3.40.50.300 2 200 2.0E-41 T 28-03-2018 CWM22_RS09435 7caf0281b05d0b15094c7410781685c1 200 SUPERFAMILY SSF52540 1 195 1.05E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09435 7caf0281b05d0b15094c7410781685c1 200 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 189 2.1E-54 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CWM22_RS09435 7caf0281b05d0b15094c7410781685c1 200 Pfam PF01121 Dephospho-CoA kinase 4 181 6.6E-52 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 SUPERFAMILY SSF55060 153 270 8.46E-30 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 SUPERFAMILY SSF54211 2 142 1.9E-29 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 Pfam PF08544 GHMP kinases C terminal 194 266 2.2E-7 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 PIRSF PIRSF000676 1 286 6.9E-83 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 Gene3D G3DSA:3.30.230.10 1 153 1.8E-25 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 PRINTS PR00958 Homoserine kinase signature 8 23 6.6E-39 T 28-03-2018 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 PRINTS PR00958 Homoserine kinase signature 156 173 6.6E-39 T 28-03-2018 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 PRINTS PR00958 Homoserine kinase signature 236 251 6.6E-39 T 28-03-2018 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 PRINTS PR00958 Homoserine kinase signature 84 99 6.6E-39 T 28-03-2018 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 PRINTS PR00958 Homoserine kinase signature 118 131 6.6E-39 T 28-03-2018 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 Gene3D G3DSA:3.30.70.890 154 286 1.5E-19 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 Pfam PF00288 GHMP kinases N terminal domain 70 131 1.3E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 77 88 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 TIGRFAM TIGR00191 thrB: homoserine kinase 1 285 7.7E-71 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CWM22_RS07120 48b62c75e8fba82120d85188a306bc31 286 Hamap MF_00384 Homoserine kinase [thrB]. 1 285 30.875 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CWM22_RS03810 21bfd473155451c3883fccd6262e09ef 65 Pfam PF00255 Glutathione peroxidase 3 48 1.1E-9 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CWM22_RS03810 21bfd473155451c3883fccd6262e09ef 65 Gene3D G3DSA:3.40.30.10 1 59 1.5E-9 T 28-03-2018 CWM22_RS03810 21bfd473155451c3883fccd6262e09ef 65 SUPERFAMILY SSF52833 1 52 3.96E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS03065 4bc392a64b771af472e664aec340f884 165 Gene3D G3DSA:3.30.450.40 3 151 1.6E-17 T 28-03-2018 IPR029016 GAF domain-like CWM22_RS03065 4bc392a64b771af472e664aec340f884 165 Pfam PF13185 GAF domain 48 148 2.0E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 CWM22_RS03065 4bc392a64b771af472e664aec340f884 165 SUPERFAMILY SSF55781 4 150 6.32E-37 T 28-03-2018 IPR029016 GAF domain-like CWM22_RS09570 06bc9d6590c594bfd0ab6b6424ada31d 112 TIGRFAM TIGR01673 holin_LLH: phage holin, LL-H family 1 106 2.9E-12 T 28-03-2018 IPR010026 Phage holin, LL-H family CWM22_RS09570 06bc9d6590c594bfd0ab6b6424ada31d 112 Pfam PF09682 Bacteriophage holin of superfamily 6 (Holin_LLH) 4 105 7.6E-27 T 28-03-2018 IPR010026 Phage holin, LL-H family CWM22_RS04175 06bc9d6590c594bfd0ab6b6424ada31d 112 TIGRFAM TIGR01673 holin_LLH: phage holin, LL-H family 1 106 2.9E-12 T 28-03-2018 IPR010026 Phage holin, LL-H family CWM22_RS04175 06bc9d6590c594bfd0ab6b6424ada31d 112 Pfam PF09682 Bacteriophage holin of superfamily 6 (Holin_LLH) 4 105 7.6E-27 T 28-03-2018 IPR010026 Phage holin, LL-H family CWM22_RS02145 98995efd7620d0164c5aea0e521dc5cd 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02145 98995efd7620d0164c5aea0e521dc5cd 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02145 98995efd7620d0164c5aea0e521dc5cd 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02145 98995efd7620d0164c5aea0e521dc5cd 115 SUPERFAMILY SSF50104 1 114 9.23E-46 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWM22_RS02145 98995efd7620d0164c5aea0e521dc5cd 115 PIRSF PIRSF002191 1 115 2.1E-49 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02145 98995efd7620d0164c5aea0e521dc5cd 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS02145 98995efd7620d0164c5aea0e521dc5cd 115 Pfam PF01245 Ribosomal protein L19 4 112 1.1E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02145 98995efd7620d0164c5aea0e521dc5cd 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 113 2.3E-48 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02145 98995efd7620d0164c5aea0e521dc5cd 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.325 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS12730 291df6cfe7f3fc4279c7ded7d7433b62 245 Gene3D G3DSA:3.40.50.2300 1 138 7.2E-12 T 28-03-2018 CWM22_RS12730 291df6cfe7f3fc4279c7ded7d7433b62 245 Pfam PF04397 LytTr DNA-binding domain 152 242 2.7E-18 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWM22_RS12730 291df6cfe7f3fc4279c7ded7d7433b62 245 Gene3D G3DSA:2.40.50.40 139 207 4.1E-11 T 28-03-2018 CWM22_RS12730 291df6cfe7f3fc4279c7ded7d7433b62 245 SMART SM00850 149 243 4.0E-14 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWM22_RS12730 291df6cfe7f3fc4279c7ded7d7433b62 245 Pfam PF00072 Response regulator receiver domain 4 123 2.4E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS12730 291df6cfe7f3fc4279c7ded7d7433b62 245 SMART SM00448 2 123 2.8E-4 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS12730 291df6cfe7f3fc4279c7ded7d7433b62 245 SUPERFAMILY SSF52172 1 129 1.57E-9 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS01860 1790de24f137d56a0e0c7e13c60d0dc4 445 Gene3D G3DSA:3.20.70.20 13 422 7.8E-179 T 28-03-2018 CWM22_RS01860 1790de24f137d56a0e0c7e13c60d0dc4 445 Pfam PF05167 Uncharacterised ACR (DUF711) 12 409 9.4E-171 T 28-03-2018 IPR007841 Uncharacterised protein family UPF0210 CWM22_RS01860 1790de24f137d56a0e0c7e13c60d0dc4 445 Hamap MF_01221 UPF0210 protein . 1 445 52.266 T 28-03-2018 IPR007841 Uncharacterised protein family UPF0210 CWM22_RS01860 1790de24f137d56a0e0c7e13c60d0dc4 445 SUPERFAMILY SSF51998 2 440 7.69E-179 T 28-03-2018 CWM22_RS08295 38b47d7965b3819a629792de2368d5d9 495 Gene3D G3DSA:1.20.1570.10 278 339 9.2E-29 T 28-03-2018 CWM22_RS08295 38b47d7965b3819a629792de2368d5d9 495 Gene3D G3DSA:3.10.630.10 3 228 2.0E-106 T 28-03-2018 CWM22_RS08295 38b47d7965b3819a629792de2368d5d9 495 Gene3D G3DSA:3.10.630.10 229 277 2.2E-15 T 28-03-2018 CWM22_RS08295 38b47d7965b3819a629792de2368d5d9 495 PIRSF PIRSF033132 2 495 1.1E-253 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CWM22_RS08295 38b47d7965b3819a629792de2368d5d9 495 Pfam PF08903 Domain of unknown function (DUF1846) 4 492 9.8E-238 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CWM22_RS08295 38b47d7965b3819a629792de2368d5d9 495 Hamap MF_01567 UPF0371 protein . 2 495 58.364 T 28-03-2018 IPR014999 Uncharacterised protein family UPF0371 CWM22_RS02540 aa2fe7de243ddf6bbf5c8bfee24ee101 430 Gene3D G3DSA:3.40.50.300 272 428 4.0E-19 T 28-03-2018 CWM22_RS02540 aa2fe7de243ddf6bbf5c8bfee24ee101 430 SUPERFAMILY SSF52540 108 401 4.57E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02540 aa2fe7de243ddf6bbf5c8bfee24ee101 430 Pfam PF00271 Helicase conserved C-terminal domain 289 393 7.7E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS02540 aa2fe7de243ddf6bbf5c8bfee24ee101 430 Gene3D G3DSA:3.40.50.300 77 252 3.0E-18 T 28-03-2018 CWM22_RS02540 aa2fe7de243ddf6bbf5c8bfee24ee101 430 Pfam PF04851 Type III restriction enzyme, res subunit 91 235 1.1E-5 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS02540 aa2fe7de243ddf6bbf5c8bfee24ee101 430 SMART SM00487 88 268 1.7E-7 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS02540 aa2fe7de243ddf6bbf5c8bfee24ee101 430 SMART SM00490 312 395 6.1E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS07015 935ce4642c6db87558213cb85be67567 241 SUPERFAMILY SSF75217 1 237 6.73E-93 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWM22_RS07015 935ce4642c6db87558213cb85be67567 241 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 241 106.213 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWM22_RS07015 935ce4642c6db87558213cb85be67567 241 Gene3D G3DSA:1.10.1270.20 164 241 2.8E-32 T 28-03-2018 CWM22_RS07015 935ce4642c6db87558213cb85be67567 241 PIRSF PIRSF000386 1 240 4.9E-97 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWM22_RS07015 935ce4642c6db87558213cb85be67567 241 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 215 7.4E-65 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWM22_RS07015 935ce4642c6db87558213cb85be67567 241 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 225 3.2E-90 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWM22_RS07015 935ce4642c6db87558213cb85be67567 241 Gene3D G3DSA:3.40.1280.10 1 163 1.9E-72 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWM22_RS03060 dd02a82ac4d7ff97a44185516561ec5e 594 Gene3D G3DSA:3.10.20.320 187 271 1.2E-6 T 28-03-2018 CWM22_RS03060 dd02a82ac4d7ff97a44185516561ec5e 594 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 560 592 6.8E-5 T 28-03-2018 CWM22_RS04485 0a235252dffb92102a1e16d325dd9fae 441 TIGRFAM TIGR02919 TIGR02919: accessory Sec system glycosyltransferase GtfB 1 440 6.3E-170 T 28-03-2018 IPR014268 Glycosyltransferase-stabilising protein Gtf2 GO:0031647 CWM22_RS04485 0a235252dffb92102a1e16d325dd9fae 441 Hamap MF_01473 Glycosyltransferase stabilizing protein Gtf2 [gtf2]. 1 441 35.925 T 28-03-2018 IPR014268 Glycosyltransferase-stabilising protein Gtf2 GO:0031647 CWM22_RS12985 7b4eb07ec414118c6bac32e79a8dffd3 190 Pfam PF13353 4Fe-4S single cluster domain 33 171 3.5E-53 T 28-03-2018 CWM22_RS12985 7b4eb07ec414118c6bac32e79a8dffd3 190 Gene3D G3DSA:3.80.30.10 83 185 1.4E-12 T 28-03-2018 CWM22_RS12985 7b4eb07ec414118c6bac32e79a8dffd3 190 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 23 173 5.2E-59 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CWM22_RS12985 7b4eb07ec414118c6bac32e79a8dffd3 190 PIRSF PIRSF000368 14 188 9.9E-72 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CWM22_RS12985 7b4eb07ec414118c6bac32e79a8dffd3 190 SUPERFAMILY SSF102114 45 125 1.88E-8 T 28-03-2018 CWM22_RS04875 81e1bcfd83c44e55607ee86357f6ee1b 180 Pfam PF10502 Signal peptidase, peptidase S26 72 161 1.4E-5 T 28-03-2018 IPR019533 Peptidase S26 CWM22_RS04875 81e1bcfd83c44e55607ee86357f6ee1b 180 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 10 168 6.4E-33 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWM22_RS04875 81e1bcfd83c44e55607ee86357f6ee1b 180 SUPERFAMILY SSF51306 24 174 8.2E-33 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWM22_RS04875 81e1bcfd83c44e55607ee86357f6ee1b 180 Gene3D G3DSA:2.10.109.10 23 178 2.1E-22 T 28-03-2018 CWM22_RS04875 81e1bcfd83c44e55607ee86357f6ee1b 180 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 71 83 3.5E-7 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWM22_RS04875 81e1bcfd83c44e55607ee86357f6ee1b 180 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 128 147 3.5E-7 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWM22_RS05375 e6d3486028c37122f79ac350e7e02543 580 Pfam PF00005 ABC transporter 354 501 9.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05375 e6d3486028c37122f79ac350e7e02543 580 SUPERFAMILY SSF52540 330 571 1.55E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05375 e6d3486028c37122f79ac350e7e02543 580 SMART SM00382 361 553 2.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05375 e6d3486028c37122f79ac350e7e02543 580 Gene3D G3DSA:3.40.50.300 322 577 2.0E-72 T 28-03-2018 CWM22_RS05375 e6d3486028c37122f79ac350e7e02543 580 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05375 e6d3486028c37122f79ac350e7e02543 580 Pfam PF00664 ABC transporter transmembrane region 22 289 4.0E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS05375 e6d3486028c37122f79ac350e7e02543 580 SUPERFAMILY SSF90123 7 316 1.57E-63 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS05375 e6d3486028c37122f79ac350e7e02543 580 Gene3D G3DSA:1.20.1560.10 2 321 2.4E-59 T 28-03-2018 CWM22_RS04125 c4076c24ec87c661cdd6b147ba5827b4 138 Pfam PF08813 Phage tail tube protein, TTP 13 132 3.1E-7 T 28-03-2018 IPR014918 Phage tail tube protein 3 CWM22_RS03640 949806eb7210e9f081421283523b0d9a 370 Pfam PF03275 UDP-galactopyranose mutase 148 350 1.3E-87 T 28-03-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CWM22_RS03640 949806eb7210e9f081421283523b0d9a 370 SUPERFAMILY SSF51971 335 366 7.65E-52 T 28-03-2018 CWM22_RS03640 949806eb7210e9f081421283523b0d9a 370 SUPERFAMILY SSF51971 2 267 7.65E-52 T 28-03-2018 CWM22_RS03640 949806eb7210e9f081421283523b0d9a 370 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 74 3.4E-19 T 28-03-2018 CWM22_RS03640 949806eb7210e9f081421283523b0d9a 370 SUPERFAMILY SSF54373 249 317 1.39E-26 T 28-03-2018 CWM22_RS03640 949806eb7210e9f081421283523b0d9a 370 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 4 366 2.9E-130 T 28-03-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CWM22_RS03640 949806eb7210e9f081421283523b0d9a 370 Gene3D G3DSA:3.40.50.720 294 370 6.0E-16 T 28-03-2018 CWM22_RS03640 949806eb7210e9f081421283523b0d9a 370 Gene3D G3DSA:3.40.50.720 1 293 4.5E-45 T 28-03-2018 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 SUPERFAMILY SSF56672 5 247 1.33E-90 T 28-03-2018 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 Gene3D G3DSA:3.30.70.270 54 125 8.7E-25 T 28-03-2018 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 Gene3D G3DSA:3.30.70.270 126 183 1.8E-14 T 28-03-2018 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 Gene3D G3DSA:3.30.1490.100 257 361 9.9E-28 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 SUPERFAMILY SSF100879 251 352 3.45E-27 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 Hamap MF_01113 DNA polymerase IV [dinB]. 11 362 38.186 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 Pfam PF00817 impB/mucB/samB family 17 167 2.6E-47 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 Pfam PF11799 impB/mucB/samB family C-terminal domain 246 356 1.4E-22 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 Gene3D G3DSA:1.10.150.20 184 256 1.5E-18 T 28-03-2018 CWM22_RS01280 732719b8bc0fcac92b5e3ee19f339d8c 364 Pfam PF11798 IMS family HHH motif 184 210 7.5E-6 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CWM22_RS07365 882a077d2424e5475fa9b44e1c04eb90 247 Gene3D G3DSA:3.40.50.300 1 241 1.5E-59 T 28-03-2018 CWM22_RS07365 882a077d2424e5475fa9b44e1c04eb90 247 SMART SM00382 26 217 1.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS07365 882a077d2424e5475fa9b44e1c04eb90 247 Pfam PF00005 ABC transporter 17 160 3.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS07365 882a077d2424e5475fa9b44e1c04eb90 247 SUPERFAMILY SSF52540 2 223 4.49E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02230 71e63530a812669ed86c08bc24bdfef2 175 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 38 137 1.4E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS02230 71e63530a812669ed86c08bc24bdfef2 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 29 139 1.8E-22 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CWM22_RS02230 71e63530a812669ed86c08bc24bdfef2 175 SUPERFAMILY SSF56784 8 150 4.91E-31 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS02230 71e63530a812669ed86c08bc24bdfef2 175 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 6 169 2.7E-40 T 28-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CWM22_RS02230 71e63530a812669ed86c08bc24bdfef2 175 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 60 131 9.1E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS02230 71e63530a812669ed86c08bc24bdfef2 175 Gene3D G3DSA:3.40.50.1000 16 166 1.3E-29 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS02230 71e63530a812669ed86c08bc24bdfef2 175 Pfam PF00702 haloacid dehalogenase-like hydrolase 16 131 1.9E-15 T 28-03-2018 CWM22_RS03190 137a1c7b9b4ea60ebe277cb851bd7a8c 178 Pfam PF12732 YtxH-like protein 10 77 7.7E-12 T 28-03-2018 IPR024623 Uncharacterised protein family YtxH CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 5 426 7.7E-120 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 Gene3D G3DSA:3.90.190.20 298 443 7.6E-25 T 28-03-2018 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 SUPERFAMILY SSF51984 3 87 8.04E-18 T 28-03-2018 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 Gene3D G3DSA:3.40.50.720 1 90 5.6E-5 T 28-03-2018 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 Pfam PF02875 Mur ligase family, glutamate ligase domain 297 381 5.4E-15 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 SUPERFAMILY SSF53244 296 430 4.03E-35 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 Pfam PF08245 Mur ligase middle domain 108 275 5.2E-24 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 SUPERFAMILY SSF53623 90 295 1.96E-55 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 2 437 34.486 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 Pfam PF01225 Mur ligase family, catalytic domain 4 103 4.1E-26 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWM22_RS10470 9bacb3f2b38577e078e603cfe72dc80b 443 Gene3D G3DSA:3.40.1190.10 92 297 2.8E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 Pfam PF14698 Argininosuccinate lyase C-terminal 366 433 1.4E-22 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 Pfam PF00206 Lyase 9 303 4.4E-75 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 Gene3D G3DSA:1.10.40.30 378 435 2.3E-22 T 28-03-2018 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 TIGRFAM TIGR00838 argH: argininosuccinate lyase 6 458 4.5E-195 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 SUPERFAMILY SSF48557 6 456 3.46E-149 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 Gene3D G3DSA:1.10.275.10 5 109 1.7E-39 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 Hamap MF_00006 Argininosuccinate lyase [argH]. 5 456 43.257 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00145 Argininosuccinate lyase family signature 145 165 2.9E-68 T 28-03-2018 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00145 Argininosuccinate lyase family signature 196 212 2.9E-68 T 28-03-2018 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00145 Argininosuccinate lyase family signature 313 332 2.9E-68 T 28-03-2018 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00145 Argininosuccinate lyase family signature 104 126 2.9E-68 T 28-03-2018 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00145 Argininosuccinate lyase family signature 278 294 2.9E-68 T 28-03-2018 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00145 Argininosuccinate lyase family signature 234 258 2.9E-68 T 28-03-2018 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 ProSitePatterns PS00163 Fumarate lyases signature. 278 287 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00149 Fumarate lyase superfamily signature 105 123 1.0E-28 T 28-03-2018 IPR000362 Fumarate lyase family CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00149 Fumarate lyase superfamily signature 150 168 1.0E-28 T 28-03-2018 IPR000362 Fumarate lyase family CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00149 Fumarate lyase superfamily signature 234 261 1.0E-28 T 28-03-2018 IPR000362 Fumarate lyase family CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 PRINTS PR00149 Fumarate lyase superfamily signature 278 294 1.0E-28 T 28-03-2018 IPR000362 Fumarate lyase family CWM22_RS12230 ca7be31bb1ff8196ffa7e94ef28d291f 464 Gene3D G3DSA:1.20.200.10 110 377 9.9E-93 T 28-03-2018 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 314 3.3E-63 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.6E-34 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 SUPERFAMILY SSF51735 3 168 3.51E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 SUPERFAMILY SSF55347 152 315 4.17E-65 T 28-03-2018 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 267 282 2.2E-30 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 2.2E-30 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 231 248 2.2E-30 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 2.2E-30 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 2.2E-30 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 1.1E-130 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 Gene3D G3DSA:3.30.360.10 162 316 4.7E-62 T 28-03-2018 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 Gene3D G3DSA:3.40.50.720 1 161 2.7E-68 T 28-03-2018 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 PIRSF PIRSF000149 1 336 5.4E-114 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS01040 ffa60022e580084ba364d35a464a80c2 336 SMART SM00846 3 152 2.3E-80 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWM22_RS09895 d0890bd8833574c552865a1eab8bfe91 230 SUPERFAMILY SSF52540 3 223 8.78E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09895 d0890bd8833574c552865a1eab8bfe91 230 Gene3D G3DSA:3.40.50.300 1 227 1.1E-65 T 28-03-2018 CWM22_RS09895 d0890bd8833574c552865a1eab8bfe91 230 SMART SM00382 29 223 6.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS09895 d0890bd8833574c552865a1eab8bfe91 230 Pfam PF00005 ABC transporter 20 167 2.4E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS09895 d0890bd8833574c552865a1eab8bfe91 230 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 3 216 6.1E-89 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CWM22_RS09895 d0890bd8833574c552865a1eab8bfe91 230 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 234 291 7.6E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 201 215 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 221 233 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 106 122 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 68 83 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 238 254 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 278 295 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 9 24 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 132 150 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 335 350 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 399 414 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 PRINTS PR01780 Lantibiotic regulatory protein signature 378 394 2.4E-53 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 Gene3D G3DSA:1.10.287.130 216 290 1.6E-10 T 28-03-2018 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 447 4.7E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 SMART SM00387 339 450 2.8E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 SMART SM00388 229 294 4.7E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 Gene3D G3DSA:3.30.565.10 297 450 3.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 SUPERFAMILY SSF47384 220 291 3.53E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS05840 9025b26ff087390c8d63e80dc09755f6 451 SUPERFAMILY SSF55874 302 446 9.17E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS03575 323c170c31992ca0e2a3adc4a692af2d 186 SUPERFAMILY SSF51161 11 179 4.99E-34 T 28-03-2018 IPR011004 Trimeric LpxA-like CWM22_RS03575 323c170c31992ca0e2a3adc4a692af2d 186 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 133 161 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWM22_RS03575 323c170c31992ca0e2a3adc4a692af2d 186 Gene3D G3DSA:2.160.10.10 23 186 2.7E-32 T 28-03-2018 CWM22_RS03575 323c170c31992ca0e2a3adc4a692af2d 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 126 159 2.1E-10 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS02680 d52cb62d928325bbcbbf3e1d69618bd1 131 Gene3D G3DSA:3.40.50.510 2 112 2.0E-26 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWM22_RS02680 d52cb62d928325bbcbbf3e1d69618bd1 131 SUPERFAMILY SSF53062 2 103 2.49E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWM22_RS02680 d52cb62d928325bbcbbf3e1d69618bd1 131 Pfam PF03610 PTS system fructose IIA component 5 99 9.3E-19 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWM22_RS00545 8bf448d74e94982e51abea20a81f02da 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 3.7E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWM22_RS00545 8bf448d74e94982e51abea20a81f02da 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 6.5E-56 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CWM22_RS00545 8bf448d74e94982e51abea20a81f02da 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.782 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWM22_RS00545 8bf448d74e94982e51abea20a81f02da 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00545 8bf448d74e94982e51abea20a81f02da 122 SMART SM01374 1 122 1.7E-83 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWM22_RS00545 8bf448d74e94982e51abea20a81f02da 122 Gene3D G3DSA:2.40.150.20 1 122 4.6E-51 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWM22_RS00545 8bf448d74e94982e51abea20a81f02da 122 SUPERFAMILY SSF50193 1 122 1.83E-49 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWM22_RS08480 c22160f166c6806bb72d42df7b692de6 199 Pfam PF13021 Domain of unknown function (DUF3885) 160 197 3.6E-13 T 28-03-2018 IPR024976 Domain of unknown function DUF3885 CWM22_RS04285 1a47ee42ba2b57916960d3a84422e726 150 SUPERFAMILY SSF160515 1 130 6.93E-31 T 28-03-2018 CWM22_RS04285 1a47ee42ba2b57916960d3a84422e726 150 Gene3D G3DSA:3.30.1330.30 2 124 9.0E-32 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWM22_RS04285 1a47ee42ba2b57916960d3a84422e726 150 PIRSF PIRSF034303 1 150 4.4E-35 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 CWM22_RS04285 1a47ee42ba2b57916960d3a84422e726 150 Pfam PF07997 Protein of unknown function (DUF1694) 2 120 1.2E-24 T 28-03-2018 IPR012543 Protein of unknown function DUF1694 CWM22_RS04720 1d2deea8e966d7853361ba26bb6deb15 246 SUPERFAMILY SSF54637 1 146 2.0E-35 T 28-03-2018 IPR029069 HotDog domain CWM22_RS04720 1d2deea8e966d7853361ba26bb6deb15 246 Gene3D G3DSA:3.10.129.10 2 142 9.7E-9 T 28-03-2018 CWM22_RS04720 1d2deea8e966d7853361ba26bb6deb15 246 Gene3D G3DSA:3.10.129.10 144 240 2.8E-13 T 28-03-2018 CWM22_RS04720 1d2deea8e966d7853361ba26bb6deb15 246 SUPERFAMILY SSF54637 152 239 4.48E-20 T 28-03-2018 IPR029069 HotDog domain CWM22_RS04720 1d2deea8e966d7853361ba26bb6deb15 246 Pfam PF01643 Acyl-ACP thioesterase 2 241 9.9E-73 T 28-03-2018 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 CWM22_RS02695 a8cd6f42393bf26693961b57c07086b2 128 Gene3D G3DSA:1.10.150.20 109 126 0.43 T 28-03-2018 CWM22_RS02695 a8cd6f42393bf26693961b57c07086b2 128 Pfam PF14520 Helix-hairpin-helix domain 70 120 3.5E-7 T 28-03-2018 CWM22_RS02695 a8cd6f42393bf26693961b57c07086b2 128 Gene3D G3DSA:1.10.150.20 70 108 6.2E-10 T 28-03-2018 CWM22_RS02695 a8cd6f42393bf26693961b57c07086b2 128 SUPERFAMILY SSF47794 72 122 5.81E-9 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CWM22_RS11100 addde953bf03bcf3e2cfbc812dd4e9ec 200 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CWM22_RS11100 addde953bf03bcf3e2cfbc812dd4e9ec 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 188 1.8E-41 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS11100 addde953bf03bcf3e2cfbc812dd4e9ec 200 PIRSF PIRSF000709 1 98 1.1E-13 T 28-03-2018 CWM22_RS11100 addde953bf03bcf3e2cfbc812dd4e9ec 200 SMART SM00855 4 153 1.2E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS11100 addde953bf03bcf3e2cfbc812dd4e9ec 200 Gene3D G3DSA:3.40.50.1240 1 196 7.3E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS11100 addde953bf03bcf3e2cfbc812dd4e9ec 200 SUPERFAMILY SSF53254 1 191 6.2E-47 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS10210 ec74a73dd64895171b1e2ab0aeb024ab 751 SUPERFAMILY SSF52540 2 178 3.61E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10210 ec74a73dd64895171b1e2ab0aeb024ab 751 Gene3D G3DSA:3.40.50.300 1 185 9.1E-11 T 28-03-2018 CWM22_RS10210 ec74a73dd64895171b1e2ab0aeb024ab 751 SUPERFAMILY SSF52540 263 352 2.17E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10210 ec74a73dd64895171b1e2ab0aeb024ab 751 SUPERFAMILY SSF52540 24 66 2.17E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10210 ec74a73dd64895171b1e2ab0aeb024ab 751 Pfam PF04851 Type III restriction enzyme, res subunit 2 175 8.3E-16 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 Gene3D G3DSA:3.20.20.80 1 468 1.1E-142 T 28-03-2018 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 3.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 3.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 3.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 3.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 3.4E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 Hamap MF_01574 6-phospho-beta-galactosidase [lacG]. 1 468 66.659 T 28-03-2018 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 Pfam PF00232 Glycosyl hydrolase family 1 3 465 1.2E-167 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 TIGRFAM TIGR01233 lacG: 6-phospho-beta-galactosidase 3 468 4.6E-277 T 28-03-2018 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85 CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 SUPERFAMILY SSF51445 2 465 1.19E-158 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS01655 4ea0584fdf64427b4890e63cee00860b 468 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWM22_RS00235 2a7a82a37598e2235dcbd7575700b807 235 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00235 2a7a82a37598e2235dcbd7575700b807 235 Gene3D G3DSA:3.30.200.20 1 92 4.0E-27 T 28-03-2018 CWM22_RS00235 2a7a82a37598e2235dcbd7575700b807 235 Gene3D G3DSA:3.30.470.20 93 219 2.5E-47 T 28-03-2018 CWM22_RS00235 2a7a82a37598e2235dcbd7575700b807 235 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 205 2.0E-70 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CWM22_RS00235 2a7a82a37598e2235dcbd7575700b807 235 Pfam PF01259 SAICAR synthetase 6 227 6.2E-64 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00235 2a7a82a37598e2235dcbd7575700b807 235 SUPERFAMILY SSF56104 12 232 1.05E-80 T 28-03-2018 CWM22_RS00235 2a7a82a37598e2235dcbd7575700b807 235 ProSitePatterns PS01058 SAICAR synthetase signature 2. 172 180 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS00235 2a7a82a37598e2235dcbd7575700b807 235 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 3 233 32.776 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWM22_RS01680 61c72daeec86c3864d486a935d6d17e1 201 Pfam PF01719 Plasmid replication protein 2 184 2.2E-57 T 28-03-2018 IPR002631 Plasmid replication protein GO:0003677|GO:0003916|GO:0005727|GO:0006260 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 SUPERFAMILY SSF55681 6 284 1.54E-128 T 28-03-2018 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 6 291 2.6E-155 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 7 283 2.3E-145 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 Gene3D G3DSA:3.30.930.10 1 208 2.6E-83 T 28-03-2018 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 5 285 57.636 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 245 261 1.7E-64 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 80 100 1.7E-64 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 137 157 1.7E-64 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 160 175 1.7E-64 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 111 135 1.7E-64 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 59 74 1.7E-64 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CWM22_RS10720 6438c9e97aed4052f64afc3360f9d9bf 305 Gene3D G3DSA:1.20.58.180 210 286 6.6E-34 T 28-03-2018 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 579 33.521 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 SUPERFAMILY SSF55681 419 578 1.65E-104 T 28-03-2018 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 SUPERFAMILY SSF55681 117 295 1.65E-104 T 28-03-2018 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 Pfam PF00152 tRNA synthetases class II (D, K and N) 121 552 2.1E-104 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 Pfam PF01336 OB-fold nucleic acid binding domain 20 103 5.7E-16 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 SUPERFAMILY SSF55261 292 414 4.09E-38 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 210 223 9.0E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 513 527 9.0E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 205 9.0E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 469 485 9.0E-24 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 SUPERFAMILY SSF50249 2 110 1.01E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 Pfam PF02938 GAD domain 313 400 3.7E-24 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 577 8.9E-232 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 Gene3D G3DSA:2.40.50.140 1 109 9.2E-27 T 28-03-2018 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 Gene3D G3DSA:3.30.930.10 134 336 2.9E-48 T 28-03-2018 CWM22_RS13175 97043776c89c9568ad2642c6d8191ec4 583 Gene3D G3DSA:3.30.930.10 337 581 6.4E-53 T 28-03-2018 CWM22_RS09505 56a4029aa5b34149727fab837e4fe990 295 SUPERFAMILY SSF161098 54 282 5.49E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS09505 56a4029aa5b34149727fab837e4fe990 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 67 283 1.5E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS09505 56a4029aa5b34149727fab837e4fe990 295 Gene3D G3DSA:1.20.58.370 2 45 9.5E-7 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CWM22_RS09505 56a4029aa5b34149727fab837e4fe990 295 Gene3D G3DSA:1.10.3720.10 61 294 4.0E-43 T 28-03-2018 CWM22_RS08000 0b4ccb8df4d400c69d0241b5305048e1 382 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 172 354 5.2E-6 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWM22_RS08000 0b4ccb8df4d400c69d0241b5305048e1 382 SUPERFAMILY SSF51726 8 382 1.96E-61 T 28-03-2018 CWM22_RS08000 0b4ccb8df4d400c69d0241b5305048e1 382 Gene3D G3DSA:3.20.20.210 1 382 6.2E-66 T 28-03-2018 CWM22_RS00985 0d005028c981eafca8899492d38956b0 259 Pfam PF10978 Protein of unknown function (DUF2785) 75 236 3.5E-31 T 28-03-2018 IPR021247 Protein of unknown function DUF2785 CWM22_RS05745 a6035aca2046cb247604279cf7f48517 76 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 22 67 4.6E-9 T 28-03-2018 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0003713|GO:0006355 CWM22_RS05745 a6035aca2046cb247604279cf7f48517 76 PIRSF PIRSF037246 1 73 2.8E-29 T 28-03-2018 IPR017154 Uncharacterised conserved protein UCP037246 CWM22_RS06465 a6035aca2046cb247604279cf7f48517 76 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 22 67 4.6E-9 T 28-03-2018 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0003713|GO:0006355 CWM22_RS06465 a6035aca2046cb247604279cf7f48517 76 PIRSF PIRSF037246 1 73 2.8E-29 T 28-03-2018 IPR017154 Uncharacterised conserved protein UCP037246 CWM22_RS06720 6ddc20800a290a67d18d64f92b80967d 221 Pfam PF16264 SatD family (SatD) 3 214 5.2E-108 T 28-03-2018 IPR032580 SatD family CWM22_RS06720 6ddc20800a290a67d18d64f92b80967d 221 Gene3D G3DSA:1.10.10.10 165 218 3.7E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07635 abca9345d2b2bd02f181ee93ad15b2e7 355 Gene3D G3DSA:1.20.1090.10 173 355 5.9E-56 T 28-03-2018 CWM22_RS07635 abca9345d2b2bd02f181ee93ad15b2e7 355 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 355 38.962 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWM22_RS07635 abca9345d2b2bd02f181ee93ad15b2e7 355 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 12 351 5.3E-122 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWM22_RS07635 abca9345d2b2bd02f181ee93ad15b2e7 355 Gene3D G3DSA:3.40.50.1970 5 172 6.9E-52 T 28-03-2018 CWM22_RS07635 abca9345d2b2bd02f181ee93ad15b2e7 355 PIRSF PIRSF001455 7 355 9.2E-105 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWM22_RS07635 abca9345d2b2bd02f181ee93ad15b2e7 355 Pfam PF01761 3-dehydroquinate synthase 67 323 1.4E-101 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWM22_RS07635 abca9345d2b2bd02f181ee93ad15b2e7 355 SUPERFAMILY SSF56796 1 353 5.1E-111 T 28-03-2018 CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 Pfam PF12848 ABC transporter 122 229 1.5E-8 T 28-03-2018 IPR032781 ABC-transporter extension domain CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 Pfam PF00005 ABC transporter 50 83 4.8E-5 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 Pfam PF00005 ABC transporter 1 40 5.9E-9 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 Pfam PF00005 ABC transporter 269 388 8.8E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 Gene3D G3DSA:3.40.50.300 224 437 7.4E-35 T 28-03-2018 CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 SUPERFAMILY SSF52540 270 435 2.82E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 ProSitePatterns PS00211 ABC transporters family signature. 360 374 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 SMART SM00382 5 128 2.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 SMART SM00382 272 433 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 SUPERFAMILY SSF52540 1 159 9.5E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08895 b519a8c3743e10c892664065d3ca8735 438 Gene3D G3DSA:3.40.50.300 1 223 1.4E-40 T 28-03-2018 CWM22_RS08015 cf2f32c667ed5c3cf940d2bd44333677 164 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 133 1.4E-45 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWM22_RS08015 cf2f32c667ed5c3cf940d2bd44333677 164 Gene3D G3DSA:3.30.70.560 1 163 3.6E-61 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWM22_RS08015 cf2f32c667ed5c3cf940d2bd44333677 164 SUPERFAMILY SSF55083 3 155 2.88E-54 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWM22_RS08015 cf2f32c667ed5c3cf940d2bd44333677 164 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 133 5.3E-36 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWM22_RS11675 11563a9bcc01f46a6ac9ef82c6d48576 257 SUPERFAMILY SSF53167 11 253 7.99E-50 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWM22_RS11675 11563a9bcc01f46a6ac9ef82c6d48576 257 Gene3D G3DSA:3.40.50.1580 24 256 3.0E-28 T 28-03-2018 CWM22_RS11675 11563a9bcc01f46a6ac9ef82c6d48576 257 Pfam PF01048 Phosphorylase superfamily 66 248 2.3E-24 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWM22_RS04905 ceae043ed30f66956bedba225c425ef8 397 SUPERFAMILY SSF161111 8 209 6.54E-51 T 28-03-2018 CWM22_RS04905 ceae043ed30f66956bedba225c425ef8 397 Gene3D G3DSA:3.30.70.1350 207 290 1.2E-16 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWM22_RS04905 ceae043ed30f66956bedba225c425ef8 397 SUPERFAMILY SSF160240 211 289 2.88E-17 T 28-03-2018 CWM22_RS04905 ceae043ed30f66956bedba225c425ef8 397 Pfam PF01545 Cation efflux family 16 207 7.3E-49 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWM22_RS04905 ceae043ed30f66956bedba225c425ef8 397 Pfam PF16916 Dimerisation domain of Zinc Transporter 213 287 1.1E-13 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWM22_RS04905 ceae043ed30f66956bedba225c425ef8 397 Gene3D G3DSA:1.20.1510.10 10 206 1.5E-41 T 28-03-2018 CWM22_RS04905 ceae043ed30f66956bedba225c425ef8 397 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 288 2.5E-61 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWM22_RS08785 d69ad76a640206839d29932e09b28f82 519 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CWM22_RS08785 d69ad76a640206839d29932e09b28f82 519 SUPERFAMILY SSF52540 70 354 6.77E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08785 d69ad76a640206839d29932e09b28f82 519 Gene3D G3DSA:3.40.50.300 5 217 8.1E-63 T 28-03-2018 CWM22_RS08785 d69ad76a640206839d29932e09b28f82 519 Pfam PF00271 Helicase conserved C-terminal domain 226 334 1.2E-29 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS08785 d69ad76a640206839d29932e09b28f82 519 SMART SM00487 20 217 3.9E-65 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS08785 d69ad76a640206839d29932e09b28f82 519 Gene3D G3DSA:3.40.50.300 218 515 1.8E-47 T 28-03-2018 CWM22_RS08785 d69ad76a640206839d29932e09b28f82 519 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 1 514 44.902 T 28-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 CWM22_RS08785 d69ad76a640206839d29932e09b28f82 519 SMART SM00490 253 334 2.5E-35 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS08785 d69ad76a640206839d29932e09b28f82 519 Pfam PF00270 DEAD/DEAH box helicase 26 190 2.1E-52 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWM22_RS08915 862197b7724f221a0a70714b359da460 234 Gene3D G3DSA:1.10.10.10 126 234 6.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08915 862197b7724f221a0a70714b359da460 234 Pfam PF00072 Response regulator receiver domain 4 112 1.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS08915 862197b7724f221a0a70714b359da460 234 SMART SM00862 154 230 2.9E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS08915 862197b7724f221a0a70714b359da460 234 SUPERFAMILY SSF52172 1 125 6.26E-42 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS08915 862197b7724f221a0a70714b359da460 234 Gene3D G3DSA:3.40.50.2300 1 125 4.1E-37 T 28-03-2018 CWM22_RS08915 862197b7724f221a0a70714b359da460 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 8.4E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS08915 862197b7724f221a0a70714b359da460 234 SMART SM00448 2 112 1.5E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS08915 862197b7724f221a0a70714b359da460 234 SUPERFAMILY SSF46894 132 230 2.34E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWM22_RS03820 73790b1d67fee40bcb9f465e9d857d17 333 Gene3D G3DSA:1.10.3470.10 2 333 3.4E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS03820 73790b1d67fee40bcb9f465e9d857d17 333 SUPERFAMILY SSF81345 4 330 3.4E-74 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWM22_RS03820 73790b1d67fee40bcb9f465e9d857d17 333 Pfam PF01032 FecCD transport family 17 330 2.0E-86 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWM22_RS11405 d63087751bea755046be5e0a7aaf2838 390 Pfam PF00953 Glycosyl transferase family 4 88 246 1.0E-40 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWM22_RS11405 d63087751bea755046be5e0a7aaf2838 390 ProSitePatterns PS01348 MraY family signature 2. 164 175 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWM22_RS08690 70c604e8ca4ab8dee4296193f5eb1efc 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 270 1.5E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS08690 70c604e8ca4ab8dee4296193f5eb1efc 276 Gene3D G3DSA:1.10.3720.10 2 264 9.6E-39 T 28-03-2018 CWM22_RS08690 70c604e8ca4ab8dee4296193f5eb1efc 276 SUPERFAMILY SSF161098 6 276 1.4E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS06805 6f84562df3018a9ce5d505a7e44ba62f 561 SUPERFAMILY SSF52540 282 462 2.5E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06805 6f84562df3018a9ce5d505a7e44ba62f 561 Pfam PF07728 AAA domain (dynein-related subfamily) 307 456 2.5E-23 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CWM22_RS06805 6f84562df3018a9ce5d505a7e44ba62f 561 Gene3D G3DSA:3.40.50.300 290 462 1.8E-22 T 28-03-2018 CWM22_RS06805 6f84562df3018a9ce5d505a7e44ba62f 561 SMART SM00382 304 462 0.0048 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS00965 4a30287a05295ad00bdc898b554c0879 94 Pfam PF15513 Domain of unknown function (DUF4651) 32 92 1.5E-25 T 28-03-2018 IPR028105 Protein of unknown function DUF4651 CWM22_RS06765 e89dc646a0f1d2cd990bcf64ffa30a4a 68 SUPERFAMILY SSF47413 9 63 6.62E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS06765 e89dc646a0f1d2cd990bcf64ffa30a4a 68 Gene3D G3DSA:1.10.260.40 8 68 6.4E-7 T 28-03-2018 CWM22_RS06765 e89dc646a0f1d2cd990bcf64ffa30a4a 68 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 10 64 4.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS01985 ebab6a2078ea18c3e76d6351520d10d3 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 222 236 4.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWM22_RS01985 ebab6a2078ea18c3e76d6351520d10d3 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 4.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWM22_RS01985 ebab6a2078ea18c3e76d6351520d10d3 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 4.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWM22_RS01985 ebab6a2078ea18c3e76d6351520d10d3 281 SUPERFAMILY SSF53474 8 277 2.03E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS01985 ebab6a2078ea18c3e76d6351520d10d3 281 Pfam PF00561 alpha/beta hydrolase fold 38 264 9.5E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWM22_RS01985 ebab6a2078ea18c3e76d6351520d10d3 281 Gene3D G3DSA:3.40.50.1820 4 281 2.6E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS12505 54f50dba15d875b228bd45f4c60e5fa9 287 TIGRFAM TIGR00542 hxl6Piso_put: putative hexulose-6-phosphate isomerase 4 286 4.5E-115 T 28-03-2018 IPR004560 L-ribulose-5-phosphate 3-epimerase GO:0005975|GO:0016861 KEGG: 00053+5.1.3.22|MetaCyc: PWY-6961 CWM22_RS12505 54f50dba15d875b228bd45f4c60e5fa9 287 Gene3D G3DSA:3.20.20.150 2 287 1.1E-57 T 28-03-2018 CWM22_RS12505 54f50dba15d875b228bd45f4c60e5fa9 287 Pfam PF01261 Xylose isomerase-like TIM barrel 22 233 1.6E-40 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWM22_RS12505 54f50dba15d875b228bd45f4c60e5fa9 287 SUPERFAMILY SSF51658 11 283 1.15E-61 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWM22_RS06790 9cf7f928bb2872472322b5abe3794a5c 77 Pfam PF11372 Domain of unknown function (DUF3173) 5 61 6.3E-25 T 28-03-2018 IPR021512 Protein of unknown function DUF3173 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF03714 Bacterial pullanase-associated domain 103 200 1.3E-10 T 28-03-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF03714 Bacterial pullanase-associated domain 1036 1137 6.8E-15 T 28-03-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF03714 Bacterial pullanase-associated domain 925 1024 1.2E-11 T 28-03-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF03714 Bacterial pullanase-associated domain 213 312 3.0E-16 T 28-03-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SUPERFAMILY SSF49452 922 1029 6.54E-28 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:2.60.40.1180 812 894 7.9E-5 T 28-03-2018 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF07501 G5 domain 1955 2027 1.0E-13 T 28-03-2018 IPR011098 G5 domain CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SUPERFAMILY SSF51445 1768 1828 3.63E-103 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SUPERFAMILY SSF51445 1372 1741 3.63E-103 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SMART SM00642 443 807 1.2E-75 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SMART SM00642 1383 1819 7.3E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:2.60.40.1180 1849 1931 5.0E-22 T 28-03-2018 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:2.20.230.10 1953 2029 5.1E-13 T 28-03-2018 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:2.60.40.10 1239 1355 5.7E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 43 3.7E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF04650 YSIRK type signal peptide 8 33 2.0E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SUPERFAMILY SSF49452 209 316 2.71E-29 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 TIGRFAM TIGR02102 pullulan_Gpos: pullulanase, extracellular 921 1961 0.0 T 28-03-2018 IPR011838 Pullulanase, extracellular CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SUPERFAMILY SSF51445 435 813 1.6E-80 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SMART SM01208 1952 2029 2.5E-17 T 28-03-2018 IPR011098 G5 domain CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 1242 1330 1.1E-9 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SUPERFAMILY SSF81296 1237 1357 2.8E-16 T 28-03-2018 IPR014756 Immunoglobulin E-set CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:3.20.20.80 430 810 1.9E-77 T 28-03-2018 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SUPERFAMILY SSF49452 1031 1141 2.45E-31 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:3.20.20.80 1357 1837 2.2E-87 T 28-03-2018 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF00128 Alpha amylase, catalytic domain 474 578 4.4E-30 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF00128 Alpha amylase, catalytic domain 1409 1511 1.5E-13 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF00128 Alpha amylase, catalytic domain 589 775 3.5E-21 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Pfam PF00128 Alpha amylase, catalytic domain 1547 1741 5.0E-5 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 SUPERFAMILY SSF49452 99 204 6.87E-24 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:2.60.40.1110 1032 1136 1.2E-19 T 28-03-2018 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:2.60.40.1110 201 311 8.4E-22 T 28-03-2018 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:2.60.40.1110 75 200 2.8E-15 T 28-03-2018 CWM22_RS12530 ad114d0b528a7f28477f08fcb387943c 2094 Gene3D G3DSA:2.60.40.1110 907 1025 1.2E-15 T 28-03-2018 CWM22_RS10225 073f2ada16e55dde85c4e893342df5c2 172 Pfam PF14278 Transcriptional regulator C-terminal region 78 153 3.0E-6 T 28-03-2018 CWM22_RS10225 073f2ada16e55dde85c4e893342df5c2 172 Gene3D G3DSA:1.10.357.10 2 171 2.2E-26 T 28-03-2018 CWM22_RS10225 073f2ada16e55dde85c4e893342df5c2 172 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 58 3.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS10225 073f2ada16e55dde85c4e893342df5c2 172 SUPERFAMILY SSF46689 2 67 3.59E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS10225 073f2ada16e55dde85c4e893342df5c2 172 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS10225 073f2ada16e55dde85c4e893342df5c2 172 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 SUPERFAMILY SSF52343 130 292 5.63E-34 T 28-03-2018 CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 Gene3D G3DSA:2.10.240.10 252 292 2.8E-16 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 SUPERFAMILY SSF63380 40 135 5.73E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 Gene3D G3DSA:3.40.50.80 137 251 2.1E-14 T 28-03-2018 CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 Gene3D G3DSA:2.40.30.10 41 133 6.5E-14 T 28-03-2018 CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 41 294 35.284 T 28-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 Pfam PF00175 Oxidoreductase NAD-binding domain 149 238 3.6E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 PIRSF PIRSF006816 38 294 2.5E-70 T 28-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 252 290 3.9E-18 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CWM22_RS05960 7f59e40027ddc6528f35103164e5e8b0 294 Pfam PF00970 Oxidoreductase FAD-binding domain 55 133 1.2E-5 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 SMART SM00382 28 229 9.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 SMART SM00382 341 516 2.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 Gene3D G3DSA:3.40.50.300 4 282 5.1E-53 T 28-03-2018 CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 Pfam PF00005 ABC transporter 333 466 2.1E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 Pfam PF00005 ABC transporter 21 184 1.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 Pfam PF12848 ABC transporter 223 290 1.4E-10 T 28-03-2018 IPR032781 ABC-transporter extension domain CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 SUPERFAMILY SSF52540 309 525 2.22E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 Gene3D G3DSA:3.40.50.300 283 570 5.0E-51 T 28-03-2018 CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 SUPERFAMILY SSF52540 6 238 5.52E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06965 f4c1d000a65a166b48b3e51822cab70f 622 Pfam PF16326 ABC transporter C-terminal domain 553 619 1.9E-16 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 Pfam PF08245 Mur ligase middle domain 117 290 2.7E-33 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 SUPERFAMILY SSF53623 103 307 6.28E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 445 5.2E-128 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 Pfam PF02875 Mur ligase family, glutamate ligase domain 310 384 8.1E-11 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 SUPERFAMILY SSF53244 309 448 3.66E-39 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 SUPERFAMILY SSF51984 10 100 4.05E-17 T 28-03-2018 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 Gene3D G3DSA:3.40.50.720 2 101 6.9E-15 T 28-03-2018 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 Gene3D G3DSA:3.90.190.20 314 447 8.2E-34 T 28-03-2018 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 448 35.656 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS02785 28978457ab37443bfccadd77441f3524 449 Gene3D G3DSA:3.40.1190.10 102 307 2.7E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWM22_RS09590 d0d4a198367ba54f23bf50097a5d964a 1411 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 19 318 3.1E-52 T 28-03-2018 IPR007119 Phage minor structural protein, N-terminal domain CWM22_RS09590 d0d4a198367ba54f23bf50097a5d964a 1411 Pfam PF07902 gp58-like protein 1045 1329 7.2E-25 T 28-03-2018 IPR012892 Gp58-like CWM22_RS09590 d0d4a198367ba54f23bf50097a5d964a 1411 Gene3D G3DSA:1.20.1480.30 309 395 0.33 T 28-03-2018 CWM22_RS09590 d0d4a198367ba54f23bf50097a5d964a 1411 Gene3D G3DSA:1.20.5.50 506 610 4.3E-7 T 28-03-2018 CWM22_RS09590 d0d4a198367ba54f23bf50097a5d964a 1411 Gene3D G3DSA:1.20.5.50 396 505 0.39 T 28-03-2018 CWM22_RS09590 d0d4a198367ba54f23bf50097a5d964a 1411 SUPERFAMILY SSF49785 928 982 4.96E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS09590 d0d4a198367ba54f23bf50097a5d964a 1411 Gene3D G3DSA:2.60.120.260 800 1016 6.4E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS09590 d0d4a198367ba54f23bf50097a5d964a 1411 Gene3D G3DSA:2.60.120.260 611 766 9.2E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS03260 efe0af932eb6ca962474f7e95b55edd9 264 Gene3D G3DSA:1.10.1900.10 9 85 3.3E-15 T 28-03-2018 CWM22_RS03260 efe0af932eb6ca962474f7e95b55edd9 264 SUPERFAMILY SSF158560 5 87 1.83E-10 T 28-03-2018 CWM22_RS09050 163ffa3135d1db70d739fcb6f1fded41 854 Pfam PF00746 LPXTG cell wall anchor motif 815 853 2.6E-8 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS09050 163ffa3135d1db70d739fcb6f1fded41 854 Gene3D G3DSA:1.10.287.620 187 324 0.097 T 28-03-2018 CWM22_RS09050 163ffa3135d1db70d739fcb6f1fded41 854 Gene3D G3DSA:1.10.287.620 39 185 1.6E-9 T 28-03-2018 CWM22_RS09050 163ffa3135d1db70d739fcb6f1fded41 854 Gene3D G3DSA:1.10.287.620 624 772 2.9E-9 T 28-03-2018 CWM22_RS09050 163ffa3135d1db70d739fcb6f1fded41 854 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 822 853 3.8E-5 T 28-03-2018 CWM22_RS09050 163ffa3135d1db70d739fcb6f1fded41 854 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 266 633 5.5E-79 T 28-03-2018 IPR027607 SEC10/PgrA surface exclusion domain CWM22_RS07995 741e7089e6a8c14c317410a29aeea155 388 Gene3D G3DSA:1.20.1250.20 194 386 2.1E-17 T 28-03-2018 CWM22_RS07995 741e7089e6a8c14c317410a29aeea155 388 Pfam PF07690 Major Facilitator Superfamily 13 347 1.3E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWM22_RS07995 741e7089e6a8c14c317410a29aeea155 388 Gene3D G3DSA:1.20.1250.20 3 193 9.0E-17 T 28-03-2018 CWM22_RS07995 741e7089e6a8c14c317410a29aeea155 388 SUPERFAMILY SSF103473 3 380 5.49E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWM22_RS10465 a9b8932368b00c04da3f27b5a9089283 161 Gene3D G3DSA:3.40.630.30 1 159 1.4E-20 T 28-03-2018 CWM22_RS10465 a9b8932368b00c04da3f27b5a9089283 161 Pfam PF00583 Acetyltransferase (GNAT) family 25 134 8.4E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS10465 a9b8932368b00c04da3f27b5a9089283 161 SUPERFAMILY SSF55729 1 146 3.01E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 Pfam PF12161 HsdM N-terminal domain 8 167 2.3E-23 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 SUPERFAMILY SSF53335 7 45 1.77E-132 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 SUPERFAMILY SSF53335 86 528 1.77E-132 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 8 505 1.1E-126 T 28-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 Gene3D G3DSA:3.40.50.150 199 487 1.6E-72 T 28-03-2018 CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 313 319 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 201 217 2.6E-22 T 28-03-2018 CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 230 244 2.6E-22 T 28-03-2018 CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 346 370 2.6E-22 T 28-03-2018 CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 310 322 2.6E-22 T 28-03-2018 CWM22_RS10850 399c5f10ea63db64d096b7b4f0ef3e2b 529 Pfam PF02384 N-6 DNA Methylase 178 493 9.8E-110 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CWM22_RS02425 0d9acaa25f4d9a0dd63e9e92ed6ea529 205 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 205 97.4 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWM22_RS02425 0d9acaa25f4d9a0dd63e9e92ed6ea529 205 PIRSF PIRSF037785 19 201 4.6E-76 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWM22_RS02425 0d9acaa25f4d9a0dd63e9e92ed6ea529 205 Pfam PF03838 Recombination protein U 28 190 2.5E-62 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWM22_RS02425 0d9acaa25f4d9a0dd63e9e92ed6ea529 205 SUPERFAMILY SSF52980 30 193 2.95E-62 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWM22_RS02425 0d9acaa25f4d9a0dd63e9e92ed6ea529 205 Gene3D G3DSA:3.40.1350.10 29 193 2.1E-60 T 28-03-2018 CWM22_RS02425 0d9acaa25f4d9a0dd63e9e92ed6ea529 205 TIGRFAM TIGR00648 recU: recombination protein U 27 192 1.1E-59 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Pfam PF04563 RNA polymerase beta subunit 28 459 5.2E-27 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Pfam PF10385 RNA polymerase beta subunit external 1 domain 550 617 5.4E-21 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1142 12.299 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 293 1.3E-23 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Pfam PF04561 RNA polymerase Rpb2, domain 2 363 413 1.8E-8 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 SUPERFAMILY SSF64484 14 291 0.0 T 28-03-2018 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 SUPERFAMILY SSF64484 381 1150 0.0 T 28-03-2018 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Gene3D G3DSA:2.40.270.10 747 839 4.6E-11 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Pfam PF04560 RNA polymerase Rpb2, domain 7 1066 1140 1.1E-25 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 220 891 5.6E-292 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Gene3D G3DSA:3.90.1110.10 137 392 1.2E-65 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Pfam PF00562 RNA polymerase Rpb2, domain 6 678 1064 3.4E-163 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Gene3D G3DSA:3.90.1100.10 393 608 1.0E-76 T 28-03-2018 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Gene3D G3DSA:3.90.1100.10 609 674 4.2E-13 T 28-03-2018 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Pfam PF04565 RNA polymerase Rpb2, domain 3 472 537 8.4E-29 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Gene3D G3DSA:2.40.50.100 675 746 3.2E-24 T 28-03-2018 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Gene3D G3DSA:2.40.270.10 840 1050 4.7E-78 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 Gene3D G3DSA:3.90.1800.10 1067 1110 3.4E-11 T 28-03-2018 CWM22_RS00870 8f701d725752d6520fd9af7622c86bf2 1190 ProSitePatterns PS01166 RNA polymerases beta chain signature. 917 929 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWM22_RS02875 60d3b66158ce7c087b38e87b743cdb70 229 SUPERFAMILY SSF161098 12 207 2.88E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS02875 60d3b66158ce7c087b38e87b743cdb70 229 Gene3D G3DSA:1.10.3720.10 1 226 9.6E-42 T 28-03-2018 CWM22_RS02875 60d3b66158ce7c087b38e87b743cdb70 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 116 4.5E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWM22_RS02875 60d3b66158ce7c087b38e87b743cdb70 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 222 7.4E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS04335 e62bcd500deabfe3aeb4fe6231d51663 111 Pfam PF01381 Helix-turn-helix 15 69 3.7E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS04335 e62bcd500deabfe3aeb4fe6231d51663 111 SMART SM00530 14 69 1.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS04335 e62bcd500deabfe3aeb4fe6231d51663 111 Gene3D G3DSA:1.10.260.40 10 106 6.6E-18 T 28-03-2018 CWM22_RS04335 e62bcd500deabfe3aeb4fe6231d51663 111 SUPERFAMILY SSF47413 9 74 5.07E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS05825 370460560022cd46727e76b84796d5a6 626 Pfam PF11083 Lantibiotic streptin immunity protein 518 608 4.6E-41 T 28-03-2018 IPR021112 Lantibiotic streptin immunity protein CWM22_RS05825 370460560022cd46727e76b84796d5a6 626 Pfam PF03432 Relaxase/Mobilisation nuclease domain 12 262 2.3E-57 T 28-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 CWM22_RS05825 370460560022cd46727e76b84796d5a6 626 Gene3D G3DSA:3.40.50.790 348 424 0.24 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 PIRSF PIRSF037875 1 454 6.4E-151 T 28-03-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 PRINTS PR00723 Subtilisin serine protease family (S8) signature 142 161 9.2E-8 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 PRINTS PR00723 Subtilisin serine protease family (S8) signature 187 200 9.2E-8 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 PRINTS PR00723 Subtilisin serine protease family (S8) signature 396 412 9.2E-8 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 SUPERFAMILY SSF52743 140 433 5.24E-55 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 147 158 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 PRINTS PR01779 Lantibiotic leader peptide processing protein signature 120 132 1.0E-8 T 28-03-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 PRINTS PR01779 Lantibiotic leader peptide processing protein signature 367 381 1.0E-8 T 28-03-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 PRINTS PR01779 Lantibiotic leader peptide processing protein signature 263 278 1.0E-8 T 28-03-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 PRINTS PR01779 Lantibiotic leader peptide processing protein signature 210 225 1.0E-8 T 28-03-2018 IPR008357 Lantibiotic leader peptide-processing serine protease GO:0004252|GO:0006508 CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 397 407 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 Gene3D G3DSA:3.40.50.200 118 451 1.9E-52 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS05830 25a85a488b0a81790ff39823ed56ae87 454 Pfam PF00082 Subtilase family 145 418 2.8E-36 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS08585 53d6e5bf2ebf1b8a964408c9815eecbc 105 Pfam PF06156 Initiation control protein YabA 1 100 2.9E-32 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CWM22_RS08585 53d6e5bf2ebf1b8a964408c9815eecbc 105 Hamap MF_01159 Initiation-control protein YabA. 1 104 22.889 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CWM22_RS08585 53d6e5bf2ebf1b8a964408c9815eecbc 105 PIRSF PIRSF021439 1 105 3.5E-37 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CWM22_RS00045 f189d8dbd588c777dfaa364027b0b71a 90 SMART SM00363 1 62 1.4E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS00045 f189d8dbd588c777dfaa364027b0b71a 90 Pfam PF01479 S4 domain 1 47 3.6E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS00045 f189d8dbd588c777dfaa364027b0b71a 90 PIRSF PIRSF038881 1 89 1.5E-39 T 28-03-2018 IPR025490 RNA-binding protein, HP1423 type CWM22_RS00045 f189d8dbd588c777dfaa364027b0b71a 90 Gene3D G3DSA:3.10.290.10 1 90 6.5E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS00045 f189d8dbd588c777dfaa364027b0b71a 90 SUPERFAMILY SSF55174 1 80 4.97E-20 T 28-03-2018 CWM22_RS02915 c5dd6a3120a0784d3e23da264b80a1ea 216 Pfam PF00072 Response regulator receiver domain 4 113 4.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS02915 c5dd6a3120a0784d3e23da264b80a1ea 216 SUPERFAMILY SSF46894 125 214 4.37E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWM22_RS02915 c5dd6a3120a0784d3e23da264b80a1ea 216 Gene3D G3DSA:1.10.10.10 116 216 9.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02915 c5dd6a3120a0784d3e23da264b80a1ea 216 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 213 2.0E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS02915 c5dd6a3120a0784d3e23da264b80a1ea 216 Gene3D G3DSA:3.40.50.2300 1 115 4.3E-33 T 28-03-2018 CWM22_RS02915 c5dd6a3120a0784d3e23da264b80a1ea 216 SMART SM00448 2 112 9.4E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS02915 c5dd6a3120a0784d3e23da264b80a1ea 216 SMART SM00862 143 213 6.8E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS02915 c5dd6a3120a0784d3e23da264b80a1ea 216 SUPERFAMILY SSF52172 2 123 3.7E-36 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS00850 a641cae7fc27e826b8e6eba8b32102fd 260 SUPERFAMILY SSF103473 48 250 6.67E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWM22_RS00850 a641cae7fc27e826b8e6eba8b32102fd 260 Pfam PF06736 Protein of unknown function (DUF1211) 62 144 5.2E-17 T 28-03-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 CWM22_RS01905 c8224947f21311085e379e82f8e1efcb 291 SUPERFAMILY SSF53850 1 270 2.87E-49 T 28-03-2018 CWM22_RS01905 c8224947f21311085e379e82f8e1efcb 291 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 68 81 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CWM22_RS01905 c8224947f21311085e379e82f8e1efcb 291 Gene3D G3DSA:3.40.190.10 2 162 9.6E-29 T 28-03-2018 CWM22_RS01905 c8224947f21311085e379e82f8e1efcb 291 SMART SM00062 45 273 3.6E-38 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS01905 c8224947f21311085e379e82f8e1efcb 291 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 270 2.2E-47 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS01905 c8224947f21311085e379e82f8e1efcb 291 Gene3D G3DSA:3.40.190.10 163 277 7.1E-13 T 28-03-2018 CWM22_RS13325 ee7db3d7c8f457579993fdfb9539651f 264 Pfam PF02361 Cobalt transport protein 13 236 9.5E-48 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CWM22_RS13325 ee7db3d7c8f457579993fdfb9539651f 264 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 1 264 36.229 T 28-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 CWM22_RS03780 32de0b75b57b5c9a73ed77416d06ab52 413 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 54 371 6.0E-11 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CWM22_RS03780 32de0b75b57b5c9a73ed77416d06ab52 413 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 12 407 3.3E-164 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CWM22_RS03780 32de0b75b57b5c9a73ed77416d06ab52 413 PIRSF PIRSF500216 10 412 1.7E-173 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CWM22_RS03780 32de0b75b57b5c9a73ed77416d06ab52 413 PIRSF PIRSF016636 15 406 1.5E-77 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CWM22_RS11555 afce9eb88bd7f4db074aeb409943be6c 173 Gene3D G3DSA:3.40.50.1010 1 73 2.0E-4 T 28-03-2018 IPR029060 PIN domain-like CWM22_RS11555 afce9eb88bd7f4db074aeb409943be6c 173 Pfam PF05991 YacP-like NYN domain 6 167 2.8E-50 T 28-03-2018 IPR010298 Protein of unknown function DUF901 CWM22_RS11465 145bb39a2f27a5f14560415777949e95 311 Pfam PF09992 Phosphodiester glycosidase 129 309 1.3E-43 T 28-03-2018 IPR018711 Phosphodiester glycosidase CWM22_RS11465 145bb39a2f27a5f14560415777949e95 311 PIRSF PIRSF031512 10 309 9.1E-11 T 28-03-2018 IPR014565 Exopolysaccharide biosynthesis, EpsL, firmicutes CWM22_RS00630 232ae6684aabcc0d21ffe838116c6ea9 128 Pfam PF01196 Ribosomal protein L17 16 128 1.2E-39 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00630 232ae6684aabcc0d21ffe838116c6ea9 128 Gene3D G3DSA:3.90.1030.10 1 128 2.2E-47 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00630 232ae6684aabcc0d21ffe838116c6ea9 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 128 5.3E-48 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00630 232ae6684aabcc0d21ffe838116c6ea9 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 128 27.567 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00630 232ae6684aabcc0d21ffe838116c6ea9 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00630 232ae6684aabcc0d21ffe838116c6ea9 128 SUPERFAMILY SSF64263 2 128 2.49E-43 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 Gene3D G3DSA:2.30.22.10 115 170 7.9E-19 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 Gene3D G3DSA:3.90.20.20 2 113 1.3E-21 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 Pfam PF01025 GrpE 11 170 3.6E-45 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 PRINTS PR00773 GrpE protein signature 121 136 1.9E-26 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 PRINTS PR00773 GrpE protein signature 44 60 1.9E-26 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 PRINTS PR00773 GrpE protein signature 72 87 1.9E-26 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 PRINTS PR00773 GrpE protein signature 149 168 1.9E-26 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 ProSitePatterns PS01071 grpE protein signature. 124 168 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 SUPERFAMILY SSF51064 121 170 6.15E-15 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 SUPERFAMILY SSF58014 26 115 2.88E-21 T 28-03-2018 CWM22_RS01885 248bf985444fbd90fdcf7ad2ca0e8592 170 Hamap MF_01151 Protein GrpE [grpE]. 2 170 19.116 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 Gene3D G3DSA:1.25.40.10 146 189 2.0E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 Gene3D G3DSA:1.25.40.10 251 320 6.4E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 SUPERFAMILY SSF48452 9 116 1.07E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 SMART SM00028 32 65 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 SMART SM00028 332 365 62.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 SMART SM00028 167 200 3.2E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 Gene3D G3DSA:1.20.58.280 190 250 2.1E-6 T 28-03-2018 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 Gene3D G3DSA:1.25.40.10 321 346 8.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 Gene3D G3DSA:1.25.40.10 77 145 1.9E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 Pfam PF13176 Tetratricopeptide repeat 337 366 0.0054 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 Gene3D G3DSA:1.25.40.10 347 408 6.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 Pfam PF13181 Tetratricopeptide repeat 168 199 1.7E-6 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 SUPERFAMILY SSF48452 97 402 3.51E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS04320 4e56a6ddc58fb833c950317216c0778b 409 Gene3D G3DSA:1.25.40.10 4 76 6.7E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS08560 dd43d305a933259f274fa6d0c37474a4 164 Gene3D G3DSA:3.30.160.70 1 73 4.1E-16 T 28-03-2018 CWM22_RS08560 dd43d305a933259f274fa6d0c37474a4 164 SUPERFAMILY SSF46767 77 158 2.49E-28 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWM22_RS08560 dd43d305a933259f274fa6d0c37474a4 164 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 127 133 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWM22_RS08560 dd43d305a933259f274fa6d0c37474a4 164 SUPERFAMILY SSF53155 3 83 4.32E-16 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWM22_RS08560 dd43d305a933259f274fa6d0c37474a4 164 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 156 6.9E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWM22_RS08560 dd43d305a933259f274fa6d0c37474a4 164 Gene3D G3DSA:1.10.10.10 74 158 9.4E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08560 dd43d305a933259f274fa6d0c37474a4 164 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 156 6.2E-31 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWM22_RS08560 dd43d305a933259f274fa6d0c37474a4 164 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 157 35.552 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CWM22_RS11980 00a066c87cd5e3e755d072da7a7593ba 292 Pfam PF00849 RNA pseudouridylate synthase 89 235 2.9E-31 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS11980 00a066c87cd5e3e755d072da7a7593ba 292 SUPERFAMILY SSF55120 83 277 1.76E-56 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS11980 00a066c87cd5e3e755d072da7a7593ba 292 Gene3D G3DSA:3.30.2350.10 82 291 7.2E-58 T 28-03-2018 CWM22_RS11980 00a066c87cd5e3e755d072da7a7593ba 292 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 126 140 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWM22_RS11510 f3fd217c7ee3ce68aa8a532d5defcce1 483 SUPERFAMILY SSF46785 411 481 4.82E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS11510 f3fd217c7ee3ce68aa8a532d5defcce1 483 Pfam PF04326 Putative DNA-binding domain 19 139 1.2E-12 T 28-03-2018 IPR007421 Schlafen, AAA domain GO:0005524 CWM22_RS11510 f3fd217c7ee3ce68aa8a532d5defcce1 483 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 307 392 6.4E-25 T 28-03-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain CWM22_RS11510 f3fd217c7ee3ce68aa8a532d5defcce1 483 Gene3D G3DSA:1.10.10.10 394 483 4.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS00460 b82f447d5f0938fc709f4c36347243c9 132 Pfam PF03960 ArsC family 28 113 7.5E-18 T 28-03-2018 IPR006660 Arsenate reductase-like CWM22_RS00460 b82f447d5f0938fc709f4c36347243c9 132 SUPERFAMILY SSF52833 1 124 1.04E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS00460 b82f447d5f0938fc709f4c36347243c9 132 Gene3D G3DSA:3.40.30.10 1 131 1.9E-32 T 28-03-2018 CWM22_RS00460 b82f447d5f0938fc709f4c36347243c9 132 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 2.7E-34 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CWM22_RS10030 75defb9e44b701d651568127e7043d7d 121 Pfam PF14478 Domain of unknown function (DUF4430) 53 118 5.9E-21 T 28-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 CWM22_RS10030 75defb9e44b701d651568127e7043d7d 121 Gene3D G3DSA:3.10.20.30 20 117 7.3E-8 T 28-03-2018 IPR012675 Beta-grasp domain CWM22_RS11790 b52017cf57d50a7232bacb6a60d93862 286 SUPERFAMILY SSF48452 190 265 9.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS11790 b52017cf57d50a7232bacb6a60d93862 286 Gene3D G3DSA:1.10.260.40 5 101 1.0E-7 T 28-03-2018 CWM22_RS11790 b52017cf57d50a7232bacb6a60d93862 286 SUPERFAMILY SSF47413 4 64 7.5E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS11790 b52017cf57d50a7232bacb6a60d93862 286 Gene3D G3DSA:1.25.40.10 132 267 2.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS03125 68ad5e5d08014490fcab02a390a87084 307 PIRSF PIRSF035875 1 290 2.5E-51 T 28-03-2018 IPR017039 Virulence factor BrkB CWM22_RS03125 68ad5e5d08014490fcab02a390a87084 307 Pfam PF03631 Virulence factor BrkB 25 278 9.2E-44 T 28-03-2018 IPR017039 Virulence factor BrkB CWM22_RS06650 f0e651be10f2888f27872a647e8e823b 274 Pfam PF00756 Putative esterase 20 268 1.5E-23 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CWM22_RS06650 f0e651be10f2888f27872a647e8e823b 274 Gene3D G3DSA:3.40.50.1820 2 274 8.6E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS06650 f0e651be10f2888f27872a647e8e823b 274 SUPERFAMILY SSF53474 4 271 2.07E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS06085 62eb6e009c37baa99964080534da07a4 595 SUPERFAMILY SSF52540 107 561 1.49E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06085 62eb6e009c37baa99964080534da07a4 595 Gene3D G3DSA:3.40.50.300 90 563 3.2E-40 T 28-03-2018 CWM22_RS06085 62eb6e009c37baa99964080534da07a4 595 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 145 552 8.7E-59 T 28-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 CWM22_RS01540 c22b87adcf12210ba64a6b66e8bf7122 327 SUPERFAMILY SSF52540 27 256 1.07E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01540 c22b87adcf12210ba64a6b66e8bf7122 327 Pfam PF00005 ABC transporter 39 182 9.9E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS01540 c22b87adcf12210ba64a6b66e8bf7122 327 SMART SM00382 47 231 2.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS01540 c22b87adcf12210ba64a6b66e8bf7122 327 Gene3D G3DSA:3.40.50.300 1 286 5.2E-53 T 28-03-2018 CWM22_RS12520 3acce15e48935b5e138eacd8ad7d2812 92 SUPERFAMILY SSF52794 1 90 1.49E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS12520 3acce15e48935b5e138eacd8ad7d2812 92 Gene3D G3DSA:3.40.50.2300 1 92 2.7E-16 T 28-03-2018 CWM22_RS12520 3acce15e48935b5e138eacd8ad7d2812 92 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 89 7.1E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS05870 545f2dd5b48260808b8828c9845dede5 997 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 741 988 3.6E-24 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CWM22_RS05870 545f2dd5b48260808b8828c9845dede5 997 Pfam PF04738 Lantibiotic dehydratase, C terminus 39 660 1.1E-81 T 28-03-2018 IPR006827 Lantibiotic dehydratase, C-terminal CWM22_RS05870 545f2dd5b48260808b8828c9845dede5 997 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 741 985 2.3E-42 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CWM22_RS12070 98e6195f5b8490e9866d90d1750c8bca 292 Gene3D G3DSA:3.90.1200.10 83 246 8.3E-17 T 28-03-2018 CWM22_RS12070 98e6195f5b8490e9866d90d1750c8bca 292 SUPERFAMILY SSF56112 10 242 1.97E-36 T 28-03-2018 IPR011009 Protein kinase-like domain CWM22_RS12070 98e6195f5b8490e9866d90d1750c8bca 292 Pfam PF01636 Phosphotransferase enzyme family 9 228 1.1E-25 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CWM22_RS12070 98e6195f5b8490e9866d90d1750c8bca 292 Gene3D G3DSA:3.30.200.20 2 82 2.7E-4 T 28-03-2018 CWM22_RS00620 1ab2bec84222afa9eb5eaa29c3737080 127 Gene3D G3DSA:3.30.420.80 1 127 2.6E-44 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00620 1ab2bec84222afa9eb5eaa29c3737080 127 ProSitePatterns PS00054 Ribosomal protein S11 signature. 95 117 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CWM22_RS00620 1ab2bec84222afa9eb5eaa29c3737080 127 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 127 33.352 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00620 1ab2bec84222afa9eb5eaa29c3737080 127 Pfam PF00411 Ribosomal protein S11 17 126 5.3E-51 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00620 1ab2bec84222afa9eb5eaa29c3737080 127 PIRSF PIRSF002131 2 127 7.1E-52 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00620 1ab2bec84222afa9eb5eaa29c3737080 127 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 8 124 7.6E-58 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00620 1ab2bec84222afa9eb5eaa29c3737080 127 SUPERFAMILY SSF53137 12 127 1.57E-48 T 28-03-2018 CWM22_RS10785 cb8199bbff831018115b6362ee810eae 523 PIRSF PIRSF002741 1 520 2.1E-106 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CWM22_RS10785 cb8199bbff831018115b6362ee810eae 523 Gene3D G3DSA:3.10.105.10 289 490 1.2E-47 T 28-03-2018 CWM22_RS10785 cb8199bbff831018115b6362ee810eae 523 Gene3D G3DSA:3.90.76.10 49 194 1.6E-33 T 28-03-2018 CWM22_RS10785 cb8199bbff831018115b6362ee810eae 523 SUPERFAMILY SSF53850 38 509 1.47E-116 T 28-03-2018 CWM22_RS10785 cb8199bbff831018115b6362ee810eae 523 Gene3D G3DSA:3.40.190.10 195 288 1.0E-25 T 28-03-2018 CWM22_RS10785 cb8199bbff831018115b6362ee810eae 523 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 440 1.8E-80 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CWM22_RS12085 881f12bd62f5083fefcca2184423b725 210 SMART SM00983 139 202 1.1E-16 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWM22_RS12085 881f12bd62f5083fefcca2184423b725 210 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 141 201 4.8E-9 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWM22_RS12085 881f12bd62f5083fefcca2184423b725 210 Gene3D G3DSA:3.40.50.10240 5 104 3.2E-23 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWM22_RS12085 881f12bd62f5083fefcca2184423b725 210 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 15 204 1.2E-49 T 28-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWM22_RS12085 881f12bd62f5083fefcca2184423b725 210 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 14 112 9.1E-19 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWM22_RS12085 881f12bd62f5083fefcca2184423b725 210 Gene3D G3DSA:2.60.120.320 105 210 1.4E-16 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWM22_RS12085 881f12bd62f5083fefcca2184423b725 210 SUPERFAMILY SSF63999 3 127 8.89E-33 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWM22_RS10765 6662e056049e9b35e18666db92d76c63 293 Gene3D G3DSA:3.40.50.300 3 276 1.4E-70 T 28-03-2018 CWM22_RS10765 6662e056049e9b35e18666db92d76c63 293 SMART SM00382 40 222 6.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS10765 6662e056049e9b35e18666db92d76c63 293 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 224 256 1.2E-7 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWM22_RS10765 6662e056049e9b35e18666db92d76c63 293 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS10765 6662e056049e9b35e18666db92d76c63 293 SUPERFAMILY SSF52540 6 244 1.08E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10765 6662e056049e9b35e18666db92d76c63 293 Pfam PF00005 ABC transporter 31 173 4.8E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS00520 601830ee0f6070738c3ccd5c26fae58e 114 ProSitePatterns PS00464 Ribosomal protein L22 signature. 87 111 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00520 601830ee0f6070738c3ccd5c26fae58e 114 SUPERFAMILY SSF54843 6 114 5.76E-43 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00520 601830ee0f6070738c3ccd5c26fae58e 114 Gene3D G3DSA:3.90.470.10 1 114 1.8E-45 T 28-03-2018 CWM22_RS00520 601830ee0f6070738c3ccd5c26fae58e 114 Pfam PF00237 Ribosomal protein L22p/L17e 9 111 4.3E-38 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00520 601830ee0f6070738c3ccd5c26fae58e 114 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 9 111 6.5E-45 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00520 601830ee0f6070738c3ccd5c26fae58e 114 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 5 114 29.43 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS03110 8f85e36c0a7d7794674d0bb420cb7e41 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 5.8E-87 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS03110 8f85e36c0a7d7794674d0bb420cb7e41 419 Gene3D G3DSA:3.65.10.10 1 87 1.7E-15 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS03110 8f85e36c0a7d7794674d0bb420cb7e41 419 Gene3D G3DSA:3.65.10.10 88 221 9.2E-26 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS03110 8f85e36c0a7d7794674d0bb420cb7e41 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 4.2E-153 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS03110 8f85e36c0a7d7794674d0bb420cb7e41 419 Gene3D G3DSA:3.65.10.10 222 419 5.1E-47 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS03110 8f85e36c0a7d7794674d0bb420cb7e41 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 40.545 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS03110 8f85e36c0a7d7794674d0bb420cb7e41 419 SUPERFAMILY SSF55205 1 418 1.39E-132 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CWM22_RS03685 80376a97472c0eff355b113e467cfbe0 439 PIRSF PIRSF006603 1 438 9.0E-86 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS03685 80376a97472c0eff355b113e467cfbe0 439 Pfam PF01554 MatE 16 175 6.3E-30 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS03685 80376a97472c0eff355b113e467cfbe0 439 Pfam PF01554 MatE 238 395 7.4E-23 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS03685 80376a97472c0eff355b113e467cfbe0 439 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 412 1.6E-72 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS03710 e62158a4d5f72d2218df911c9f520874 231 SUPERFAMILY SSF51206 22 145 5.89E-28 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CWM22_RS03710 e62158a4d5f72d2218df911c9f520874 231 Pfam PF13545 Crp-like helix-turn-helix domain 160 222 1.7E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CWM22_RS03710 e62158a4d5f72d2218df911c9f520874 231 SUPERFAMILY SSF46785 151 225 2.25E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03710 e62158a4d5f72d2218df911c9f520874 231 Gene3D G3DSA:2.60.120.10 4 150 5.5E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWM22_RS03710 e62158a4d5f72d2218df911c9f520874 231 Pfam PF00027 Cyclic nucleotide-binding domain 34 115 7.9E-10 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CWM22_RS03710 e62158a4d5f72d2218df911c9f520874 231 Gene3D G3DSA:1.10.10.10 151 231 1.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03710 e62158a4d5f72d2218df911c9f520874 231 SMART SM00100 15 133 0.0049 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CWM22_RS01065 0eedde3048cde2b14aac6b86f537427b 448 SUPERFAMILY SSF54368 4 105 8.5E-30 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWM22_RS01065 0eedde3048cde2b14aac6b86f537427b 448 SMART SM01230 106 358 7.6E-131 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWM22_RS01065 0eedde3048cde2b14aac6b86f537427b 448 SUPERFAMILY SSF55931 107 446 2.65E-123 T 28-03-2018 CWM22_RS01065 0eedde3048cde2b14aac6b86f537427b 448 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 99 5.2E-29 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWM22_RS01065 0eedde3048cde2b14aac6b86f537427b 448 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 446 6.3E-168 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWM22_RS01065 0eedde3048cde2b14aac6b86f537427b 448 Gene3D G3DSA:3.10.20.70 1 105 3.4E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWM22_RS01065 0eedde3048cde2b14aac6b86f537427b 448 Pfam PF00120 Glutamine synthetase, catalytic domain 107 444 8.5E-138 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWM22_RS01065 0eedde3048cde2b14aac6b86f537427b 448 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CWM22_RS01065 0eedde3048cde2b14aac6b86f537427b 448 Gene3D G3DSA:3.30.590.10 106 448 3.3E-123 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 SUPERFAMILY SSF53697 245 603 9.37E-90 T 28-03-2018 CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 Gene3D G3DSA:3.60.20.10 2 238 2.0E-60 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 Pfam PF13522 Glutamine amidotransferase domain 61 188 4.2E-21 T 28-03-2018 CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 603 37.9 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 Pfam PF01380 SIS domain 459 584 2.0E-17 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 Pfam PF01380 SIS domain 289 413 6.1E-26 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 Gene3D G3DSA:3.40.50.10490 455 601 5.8E-39 T 28-03-2018 CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 SUPERFAMILY SSF56235 2 232 2.66E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 603 1.8E-208 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CWM22_RS04880 b9374fde217645c5eda6b6ca23949322 603 Gene3D G3DSA:3.40.50.10490 239 454 1.7E-50 T 28-03-2018 CWM22_RS02305 2086a220976ed8fd1dc96d9b598b1959 239 SMART SM00422 3 71 8.0E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS02305 2086a220976ed8fd1dc96d9b598b1959 239 SUPERFAMILY SSF46955 3 106 1.47E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain CWM22_RS02305 2086a220976ed8fd1dc96d9b598b1959 239 Gene3D G3DSA:1.10.490.50 151 239 2.2E-20 T 28-03-2018 CWM22_RS02305 2086a220976ed8fd1dc96d9b598b1959 239 Gene3D G3DSA:1.10.1660.10 1 58 1.6E-18 T 28-03-2018 CWM22_RS02305 2086a220976ed8fd1dc96d9b598b1959 239 Gene3D G3DSA:1.10.1660.10 59 150 1.5E-8 T 28-03-2018 CWM22_RS02305 2086a220976ed8fd1dc96d9b598b1959 239 SUPERFAMILY SSF89082 150 238 3.14E-25 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CWM22_RS02305 2086a220976ed8fd1dc96d9b598b1959 239 Pfam PF13411 MerR HTH family regulatory protein 3 68 8.6E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS02305 2086a220976ed8fd1dc96d9b598b1959 239 Pfam PF07739 TipAS antibiotic-recognition domain 125 236 4.5E-28 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CWM22_RS02415 fc427f48df1c818c44a6234a950d30a6 237 Pfam PF02527 rRNA small subunit methyltransferase G 21 195 7.8E-48 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWM22_RS02415 fc427f48df1c818c44a6234a950d30a6 237 Gene3D G3DSA:3.40.50.150 3 237 1.2E-35 T 28-03-2018 CWM22_RS02415 fc427f48df1c818c44a6234a950d30a6 237 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 217 2.2E-47 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWM22_RS02415 fc427f48df1c818c44a6234a950d30a6 237 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 215 27.488 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWM22_RS02415 fc427f48df1c818c44a6234a950d30a6 237 PIRSF PIRSF003078 4 220 1.0E-49 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWM22_RS02415 fc427f48df1c818c44a6234a950d30a6 237 SUPERFAMILY SSF53335 1 237 3.72E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS12770 fc9473200e22b5efec1a571ec0a7bdf5 317 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 4 300 8.5E-70 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CWM22_RS12770 fc9473200e22b5efec1a571ec0a7bdf5 317 SUPERFAMILY SSF53335 52 305 1.09E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS12770 fc9473200e22b5efec1a571ec0a7bdf5 317 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 307 4.8E-110 T 28-03-2018 CWM22_RS12770 fc9473200e22b5efec1a571ec0a7bdf5 317 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 4 307 33.798 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CWM22_RS12770 fc9473200e22b5efec1a571ec0a7bdf5 317 PIRSF PIRSF000401 2 309 3.6E-108 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CWM22_RS12770 fc9473200e22b5efec1a571ec0a7bdf5 317 Gene3D G3DSA:3.40.50.150 111 307 1.7E-34 T 28-03-2018 CWM22_RS07595 98c21bcacd0ceeed8f88a6cdfa03123b 451 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 125 450 3.7E-24 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CWM22_RS07595 98c21bcacd0ceeed8f88a6cdfa03123b 451 SUPERFAMILY SSF50249 2 57 2.11E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS07595 98c21bcacd0ceeed8f88a6cdfa03123b 451 SUPERFAMILY SSF53335 73 450 1.01E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS07595 98c21bcacd0ceeed8f88a6cdfa03123b 451 Gene3D G3DSA:2.40.50.140 1 57 7.2E-17 T 28-03-2018 CWM22_RS07595 98c21bcacd0ceeed8f88a6cdfa03123b 451 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 381 412 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CWM22_RS07595 98c21bcacd0ceeed8f88a6cdfa03123b 451 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 15 443 4.6E-128 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CWM22_RS07595 98c21bcacd0ceeed8f88a6cdfa03123b 451 Gene3D G3DSA:3.40.50.150 73 449 2.3E-50 T 28-03-2018 CWM22_RS01080 a01f7ce133a318e896efc1593dcc29d3 288 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 68 283 9.7E-38 T 28-03-2018 IPR010057 Transcription activator MutR, C-terminal CWM22_RS01080 a01f7ce133a318e896efc1593dcc29d3 288 SUPERFAMILY SSF47413 7 68 6.05E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS01080 a01f7ce133a318e896efc1593dcc29d3 288 Gene3D G3DSA:1.10.260.40 2 272 2.6E-4 T 28-03-2018 CWM22_RS07870 816a146b94e4536285df815477c7ff4f 142 PRINTS PR01002 Flagellar protein FlgJ signature 118 136 1.1E-11 T 28-03-2018 CWM22_RS07870 816a146b94e4536285df815477c7ff4f 142 PRINTS PR01002 Flagellar protein FlgJ signature 50 71 1.1E-11 T 28-03-2018 CWM22_RS07870 816a146b94e4536285df815477c7ff4f 142 PRINTS PR01002 Flagellar protein FlgJ signature 28 49 1.1E-11 T 28-03-2018 CWM22_RS07870 816a146b94e4536285df815477c7ff4f 142 SMART SM00047 1 141 6.4E-33 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWM22_RS07870 816a146b94e4536285df815477c7ff4f 142 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 3 137 3.5E-24 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWM22_RS07870 816a146b94e4536285df815477c7ff4f 142 Gene3D G3DSA:1.10.530.10 1 141 6.6E-37 T 28-03-2018 CWM22_RS04770 8ba7faf711acde246d3b82d41ec4dab2 127 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 126 8.9E-36 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWM22_RS04770 8ba7faf711acde246d3b82d41ec4dab2 127 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 126 3.2E-33 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWM22_RS04770 8ba7faf711acde246d3b82d41ec4dab2 127 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 1.1E-5 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWM22_RS04770 8ba7faf711acde246d3b82d41ec4dab2 127 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.1E-5 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWM22_RS04770 8ba7faf711acde246d3b82d41ec4dab2 127 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 1.1E-5 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWM22_RS04770 8ba7faf711acde246d3b82d41ec4dab2 127 SUPERFAMILY SSF81330 10 122 2.09E-26 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWM22_RS08535 577014fa06355e8b4f91ab9accefaee2 287 SUPERFAMILY SSF49478 155 232 1.84E-5 T 28-03-2018 CWM22_RS08535 577014fa06355e8b4f91ab9accefaee2 287 Gene3D G3DSA:2.60.40.810 134 252 4.7E-16 T 28-03-2018 CWM22_RS00385 fa44d3f0f66c53e6441b894ff6745627 204 SUPERFAMILY SSF56784 4 200 1.04E-41 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS00385 fa44d3f0f66c53e6441b894ff6745627 204 Gene3D G3DSA:3.40.50.1000 2 200 8.6E-27 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS00385 fa44d3f0f66c53e6441b894ff6745627 204 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 97 175 6.9E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWM22_RS00385 fa44d3f0f66c53e6441b894ff6745627 204 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 180 1.2E-29 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS10125 598d1f783b4365f6d19b12bc43b556d5 103 Pfam PF11674 Protein of unknown function (DUF3270) 3 89 4.7E-30 T 28-03-2018 IPR021688 Protein of unknown function DUF3270 CWM22_RS09420 10b776cc8ee1a83e254822a85129d744 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 74 3.4E-16 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWM22_RS09420 10b776cc8ee1a83e254822a85129d744 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 4.8E-6 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWM22_RS09420 10b776cc8ee1a83e254822a85129d744 77 PRINTS PR01651 Protein-export SecG membrane protein signature 55 77 4.8E-6 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWM22_RS09420 10b776cc8ee1a83e254822a85129d744 77 Pfam PF03840 Preprotein translocase SecG subunit 5 74 5.0E-15 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 3 119 5.9E-38 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 254 272 4.3E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 153 173 4.3E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 32 54 4.3E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 202 231 4.3E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 73 100 4.3E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 108 129 4.3E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 237 253 4.3E-84 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 122 279 2.8E-70 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 Gene3D G3DSA:3.40.50.720 139 262 1.5E-42 T 28-03-2018 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 SUPERFAMILY SSF51735 121 278 1.98E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 258 266 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 Hamap MF_01576 Bifunctional protein FolD [folD]. 1 281 38.056 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 SUPERFAMILY SSF53223 2 120 9.59E-38 T 28-03-2018 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 Gene3D G3DSA:3.40.50.10860 9 138 3.3E-47 T 28-03-2018 CWM22_RS02885 e3e5574d2953620e0acc219efa42f6cb 282 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 74 99 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWM22_RS07905 e47c13f68817857305d428e9511c083e 289 SUPERFAMILY SSF53448 1 286 5.86E-93 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07905 e47c13f68817857305d428e9511c083e 289 Gene3D G3DSA:3.90.550.10 1 289 7.8E-73 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07905 e47c13f68817857305d428e9511c083e 289 Pfam PF00483 Nucleotidyl transferase 2 237 4.0E-71 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWM22_RS07905 e47c13f68817857305d428e9511c083e 289 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.4E-153 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CWM22_RS04355 55495fa62ccf1c62beff02b7c8220ec4 252 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS04355 55495fa62ccf1c62beff02b7c8220ec4 252 Gene3D G3DSA:3.40.50.300 1 252 1.2E-58 T 28-03-2018 CWM22_RS04355 55495fa62ccf1c62beff02b7c8220ec4 252 Pfam PF00005 ABC transporter 25 180 7.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS04355 55495fa62ccf1c62beff02b7c8220ec4 252 SUPERFAMILY SSF52540 4 238 1.92E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04355 55495fa62ccf1c62beff02b7c8220ec4 252 SMART SM00382 34 229 3.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS00925 3bde58e82203eb1ef5dc8763fc585253 317 SUPERFAMILY SSF53335 39 289 3.85E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS00925 3bde58e82203eb1ef5dc8763fc585253 317 Pfam PF02384 N-6 DNA Methylase 68 283 2.2E-10 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CWM22_RS00925 3bde58e82203eb1ef5dc8763fc585253 317 Gene3D G3DSA:3.40.50.150 88 315 2.3E-28 T 28-03-2018 CWM22_RS01700 32fd3219fbb71b6a7b86fbd1ba059771 142 SUPERFAMILY SSF88659 56 140 1.4E-7 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS01700 32fd3219fbb71b6a7b86fbd1ba059771 142 Gene3D G3DSA:1.10.10.10 69 142 8.2E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03405 827f8e42cd45c78cb897562321232577 98 Gene3D G3DSA:1.20.1440.50 4 91 7.1E-16 T 28-03-2018 IPR023130 Ta0600-like domain CWM22_RS03405 827f8e42cd45c78cb897562321232577 98 SUPERFAMILY SSF109797 3 86 2.07E-10 T 28-03-2018 CWM22_RS12395 4caae036b0400e4cd2c2475cfb5f9d45 411 Gene3D G3DSA:3.40.50.360 1 183 2.4E-26 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS12395 4caae036b0400e4cd2c2475cfb5f9d45 411 Gene3D G3DSA:1.20.120.520 184 256 0.0012 T 28-03-2018 CWM22_RS12395 4caae036b0400e4cd2c2475cfb5f9d45 411 Pfam PF13596 PAS domain 242 355 3.4E-28 T 28-03-2018 CWM22_RS12395 4caae036b0400e4cd2c2475cfb5f9d45 411 Pfam PF03358 NADPH-dependent FMN reductase 1 147 2.3E-33 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWM22_RS12395 4caae036b0400e4cd2c2475cfb5f9d45 411 SUPERFAMILY SSF52218 1 173 4.19E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain CWM22_RS10255 fc823b3791ba00fffbcf1b56fdb17d6f 173 Pfam PF04892 VanZ like family 25 163 4.9E-20 T 28-03-2018 IPR006976 VanZ-like CWM22_RS04910 121e363bc2a6a99eb4c2dd10c01c1057 150 Pfam PF12821 Threonine/Serine exporter, ThrE 9 132 4.0E-22 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CWM22_RS06210 96cf613db7ebd20f770d7729c478e70e 475 SUPERFAMILY SSF53067 245 468 7.28E-29 T 28-03-2018 CWM22_RS06210 96cf613db7ebd20f770d7729c478e70e 475 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 249 440 2.4E-16 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CWM22_RS06210 96cf613db7ebd20f770d7729c478e70e 475 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 238 2.9E-38 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CWM22_RS06210 96cf613db7ebd20f770d7729c478e70e 475 SUPERFAMILY SSF53067 3 240 2.22E-47 T 28-03-2018 CWM22_RS06210 96cf613db7ebd20f770d7729c478e70e 475 Gene3D G3DSA:3.30.420.40 1 236 3.6E-47 T 28-03-2018 CWM22_RS06210 96cf613db7ebd20f770d7729c478e70e 475 PIRSF PIRSF000538 357 474 1.9E-10 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWM22_RS06210 96cf613db7ebd20f770d7729c478e70e 475 PIRSF PIRSF000538 1 300 5.2E-36 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWM22_RS06210 96cf613db7ebd20f770d7729c478e70e 475 Gene3D G3DSA:3.30.420.40 237 472 3.0E-38 T 28-03-2018 CWM22_RS09320 2841b5096621202576e161d26460d361 286 Pfam PF00005 ABC transporter 18 156 2.4E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS09320 2841b5096621202576e161d26460d361 286 SUPERFAMILY SSF52540 3 208 6.12E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09320 2841b5096621202576e161d26460d361 286 Gene3D G3DSA:3.40.50.300 2 235 2.0E-54 T 28-03-2018 CWM22_RS09320 2841b5096621202576e161d26460d361 286 SMART SM00382 27 204 5.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 SUPERFAMILY SSF47323 362 578 2.24E-44 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 Pfam PF01588 Putative tRNA binding domain 571 664 6.2E-26 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 360 371 2.1E-33 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 2.1E-33 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 234 245 2.1E-33 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 268 283 2.1E-33 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 2.1E-33 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 2.1E-33 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 Gene3D G3DSA:2.40.50.140 557 667 2.8E-28 T 28-03-2018 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 519 48.921 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 492 3.7E-167 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 SUPERFAMILY SSF52374 3 359 2.31E-101 T 28-03-2018 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 540 666 4.6E-41 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 Pfam PF09334 tRNA synthetases class I (M) 6 372 5.0E-111 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 Gene3D G3DSA:1.10.730.10 357 522 1.2E-34 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 SUPERFAMILY SSF50249 564 666 2.35E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS08445 97274ffe61710037a1e4e5ea3ed7e1b9 667 Gene3D G3DSA:3.40.50.620 3 356 4.4E-88 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS11810 3effe9b3b54f5532d23b86271d45b937 350 SMART SM01329 4 341 4.7E-184 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWM22_RS11810 3effe9b3b54f5532d23b86271d45b937 350 Gene3D G3DSA:3.40.718.10 1 349 1.4E-123 T 28-03-2018 CWM22_RS11810 3effe9b3b54f5532d23b86271d45b937 350 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 236 255 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CWM22_RS11810 3effe9b3b54f5532d23b86271d45b937 350 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 345 46.316 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CWM22_RS11810 3effe9b3b54f5532d23b86271d45b937 350 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 345 1.7E-142 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CWM22_RS11810 3effe9b3b54f5532d23b86271d45b937 350 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 341 1.2E-127 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWM22_RS11810 3effe9b3b54f5532d23b86271d45b937 350 SUPERFAMILY SSF53659 4 345 8.83E-119 T 28-03-2018 CWM22_RS08335 67379045a3f9174c861538b558505cb7 72 Gene3D G3DSA:3.40.30.10 1 72 1.1E-13 T 28-03-2018 CWM22_RS08335 67379045a3f9174c861538b558505cb7 72 Pfam PF00462 Glutaredoxin 2 56 2.9E-13 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CWM22_RS08335 67379045a3f9174c861538b558505cb7 72 SUPERFAMILY SSF52833 1 70 7.91E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS08335 67379045a3f9174c861538b558505cb7 72 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 2 72 2.0E-34 T 28-03-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 CWM22_RS09360 dd48f291aa0bb432c5242101daa8804a 188 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 142 170 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWM22_RS09360 dd48f291aa0bb432c5242101daa8804a 188 SUPERFAMILY SSF51161 60 187 7.49E-38 T 28-03-2018 IPR011004 Trimeric LpxA-like CWM22_RS09360 dd48f291aa0bb432c5242101daa8804a 188 Gene3D G3DSA:2.160.10.10 12 187 2.1E-37 T 28-03-2018 CWM22_RS09360 dd48f291aa0bb432c5242101daa8804a 188 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 168 2.7E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS09605 767c6275b1388bec22f21a74995a6cb5 127 Pfam PF17318 Family of unknown function (DUF5361) 9 94 2.5E-39 T 28-03-2018 IPR035286 Protein of unknown function DUF5361 CWM22_RS10190 174e606cf871a3a3fa384be9ae574bff 380 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 62 370 3.4E-68 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CWM22_RS10190 174e606cf871a3a3fa384be9ae574bff 380 Gene3D G3DSA:3.20.20.300 45 380 1.4E-74 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CWM22_RS10190 174e606cf871a3a3fa384be9ae574bff 380 SUPERFAMILY SSF51445 51 379 3.26E-70 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS10190 174e606cf871a3a3fa384be9ae574bff 380 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 294 311 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CWM22_RS10305 a77cdf5d59e28238d6b2579ae83bef10 354 Gene3D G3DSA:3.30.565.10 206 354 3.4E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS10305 a77cdf5d59e28238d6b2579ae83bef10 354 Pfam PF07730 Histidine kinase 163 228 3.9E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CWM22_RS10305 a77cdf5d59e28238d6b2579ae83bef10 354 SUPERFAMILY SSF55874 237 336 2.26E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS07625 c68afc2d081118d715487a6a7ff724a5 341 PIRSF PIRSF001361 1 341 1.4E-113 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CWM22_RS07625 c68afc2d081118d715487a6a7ff724a5 341 Pfam PF00793 DAHP synthetase I family 34 333 1.7E-49 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CWM22_RS07625 c68afc2d081118d715487a6a7ff724a5 341 SUPERFAMILY SSF51569 4 340 2.05E-92 T 28-03-2018 CWM22_RS07625 c68afc2d081118d715487a6a7ff724a5 341 Gene3D G3DSA:3.20.20.70 1 341 9.4E-83 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS07625 c68afc2d081118d715487a6a7ff724a5 341 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 30 341 2.1E-75 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CWM22_RS08710 141bf3b395156f51f5e8f019f6336cbc 338 SMART SM00354 5 75 4.2E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS08710 141bf3b395156f51f5e8f019f6336cbc 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 9.2E-9 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS08710 141bf3b395156f51f5e8f019f6336cbc 338 Gene3D G3DSA:3.40.50.2300 162 338 6.5E-22 T 28-03-2018 CWM22_RS08710 141bf3b395156f51f5e8f019f6336cbc 338 Gene3D G3DSA:3.40.50.2300 62 161 1.2E-17 T 28-03-2018 CWM22_RS08710 141bf3b395156f51f5e8f019f6336cbc 338 SUPERFAMILY SSF47413 4 63 5.91E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS08710 141bf3b395156f51f5e8f019f6336cbc 338 SUPERFAMILY SSF53822 62 317 4.5E-44 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS08710 141bf3b395156f51f5e8f019f6336cbc 338 Pfam PF13377 Periplasmic binding protein-like domain 190 337 6.0E-15 T 28-03-2018 CWM22_RS08710 141bf3b395156f51f5e8f019f6336cbc 338 Gene3D G3DSA:1.10.260.40 21 61 1.5E-14 T 28-03-2018 CWM22_RS08710 141bf3b395156f51f5e8f019f6336cbc 338 Gene3D G3DSA:1.10.10.60 1 20 0.0018 T 28-03-2018 CWM22_RS01950 63ef87910d4790180ff59d56b107be5f 253 Pfam PF08543 Phosphomethylpyrimidine kinase 13 247 1.6E-60 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CWM22_RS01950 63ef87910d4790180ff59d56b107be5f 253 Gene3D G3DSA:3.40.1190.20 1 252 1.3E-42 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS01950 63ef87910d4790180ff59d56b107be5f 253 SUPERFAMILY SSF53613 1 247 2.03E-55 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS07205 70beaf52c8ced020b8ba28bb468628f3 154 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 151 15.576 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWM22_RS07205 70beaf52c8ced020b8ba28bb468628f3 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 92 107 8.2E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWM22_RS07205 70beaf52c8ced020b8ba28bb468628f3 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 126 142 8.2E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWM22_RS07205 70beaf52c8ced020b8ba28bb468628f3 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 48 56 8.2E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWM22_RS07205 70beaf52c8ced020b8ba28bb468628f3 154 ProSitePatterns PS00855 Signal peptidases II signature. 95 107 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWM22_RS07205 70beaf52c8ced020b8ba28bb468628f3 154 TIGRFAM TIGR00077 lspA: signal peptidase II 8 149 9.4E-35 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWM22_RS07205 70beaf52c8ced020b8ba28bb468628f3 154 Pfam PF01252 Signal peptidase (SPase) II 10 144 1.6E-37 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWM22_RS06690 2123afdbfe4c0971c1dc8ac8d240f980 85 Gene3D G3DSA:3.30.2310.20 1 84 1.7E-17 T 28-03-2018 CWM22_RS06690 2123afdbfe4c0971c1dc8ac8d240f980 85 SUPERFAMILY SSF143011 5 75 2.09E-18 T 28-03-2018 IPR035095 Toxin RelE-like domain CWM22_RS06690 2123afdbfe4c0971c1dc8ac8d240f980 85 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 10 73 2.2E-7 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CWM22_RS02640 6e0356cbe2a53a29502709656245cbad 177 SUPERFAMILY SSF159234 4 170 3.53E-32 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CWM22_RS02640 6e0356cbe2a53a29502709656245cbad 177 Hamap MF_01568 UPF0374 protein . 1 175 49.06 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 CWM22_RS02640 6e0356cbe2a53a29502709656245cbad 177 PIRSF PIRSF028345 1 177 1.1E-75 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 CWM22_RS02640 6e0356cbe2a53a29502709656245cbad 177 Gene3D G3DSA:2.40.380.10 15 170 1.9E-31 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CWM22_RS02640 6e0356cbe2a53a29502709656245cbad 177 Pfam PF04167 Protein of unknown function (DUF402) 60 124 3.4E-17 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 SUPERFAMILY SSF54373 253 349 3.79E-11 T 28-03-2018 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 Pfam PF01266 FAD dependent oxidoreductase 21 352 3.8E-55 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 465 586 5.8E-16 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 Gene3D G3DSA:3.50.50.60 3 221 1.9E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 2.6E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 2.6E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 2.6E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 2.6E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 425 437 2.6E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 349 2.6E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 SUPERFAMILY SSF51905 7 124 1.8E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 SUPERFAMILY SSF51905 160 258 1.8E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS07450 268c6000bf319cd14e52809cd19cfa3c 609 Gene3D G3DSA:3.30.9.10 222 350 1.1E-39 T 28-03-2018 CWM22_RS06580 5a847e45520b5d46277c59ab4c249b3b 51 Pfam PF04604 Type-A lantibiotic 1 50 2.7E-27 T 28-03-2018 IPR007682 Lantibiotic, type A, Lactobacillales-type GO:0005576|GO:0042742 CWM22_RS05620 077e0ebb055d60877bb7108f953fe5a8 63 Gene3D G3DSA:3.90.182.10 2 59 5.7E-14 T 28-03-2018 CWM22_RS05620 077e0ebb055d60877bb7108f953fe5a8 63 SUPERFAMILY SSF103647 9 58 6.93E-5 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CWM22_RS00230 b5dad96e92fb1c074f5204ddbe63d2b1 82 SUPERFAMILY SSF47336 1 79 2.09E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWM22_RS00230 b5dad96e92fb1c074f5204ddbe63d2b1 82 Gene3D G3DSA:1.10.1200.10 1 81 2.5E-17 T 28-03-2018 CWM22_RS00230 b5dad96e92fb1c074f5204ddbe63d2b1 82 Pfam PF00550 Phosphopantetheine attachment site 9 74 4.3E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWM22_RS00230 b5dad96e92fb1c074f5204ddbe63d2b1 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 36 74 3.0E-5 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWM22_RS00230 b5dad96e92fb1c074f5204ddbe63d2b1 82 Hamap MF_01217 Acyl carrier protein [acpP]. 5 78 14.92 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWM22_RS02240 fdf8be3a03a226626ad0b6aa7c5cce01 103 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 97 2.0E-25 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CWM22_RS02240 fdf8be3a03a226626ad0b6aa7c5cce01 103 Gene3D G3DSA:3.30.110.60 2 98 5.5E-25 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWM22_RS02240 fdf8be3a03a226626ad0b6aa7c5cce01 103 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 1.0E-19 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWM22_RS02240 fdf8be3a03a226626ad0b6aa7c5cce01 103 SMART SM01103 3 86 3.9E-33 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWM22_RS02240 fdf8be3a03a226626ad0b6aa7c5cce01 103 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 10 97 7.0E-44 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWM22_RS02240 fdf8be3a03a226626ad0b6aa7c5cce01 103 SUPERFAMILY SSF75471 1 96 2.09E-26 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWM22_RS11355 a1186e5df4ceb7648a931bd48e761a62 318 Gene3D G3DSA:1.10.3720.10 1 305 1.7E-40 T 28-03-2018 CWM22_RS11355 a1186e5df4ceb7648a931bd48e761a62 318 SUPERFAMILY SSF161098 90 298 1.83E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS11355 a1186e5df4ceb7648a931bd48e761a62 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 316 1.7E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS12100 0f3ceaa2888990e1583608ece0c3d07e 417 Pfam PF00746 LPXTG cell wall anchor motif 380 417 7.0E-8 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS12100 0f3ceaa2888990e1583608ece0c3d07e 417 Pfam PF04886 PT repeat 239 273 1.2E-6 T 28-03-2018 IPR006970 PT repeat CWM22_RS12100 0f3ceaa2888990e1583608ece0c3d07e 417 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 383 416 9.4E-7 T 28-03-2018 CWM22_RS10555 65c19ed8260b8c256e925c527000acf2 179 Pfam PF02620 Uncharacterized ACR, COG1399 54 174 3.1E-19 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CWM22_RS10995 84d86478a183b611e226448b6efab362 293 ProSitePatterns PS01125 ROK family signature. 131 156 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWM22_RS10995 84d86478a183b611e226448b6efab362 293 Gene3D G3DSA:3.30.420.40 2 136 1.3E-20 T 28-03-2018 CWM22_RS10995 84d86478a183b611e226448b6efab362 293 SUPERFAMILY SSF53067 5 290 1.84E-42 T 28-03-2018 CWM22_RS10995 84d86478a183b611e226448b6efab362 293 Pfam PF00480 ROK family 5 289 3.8E-77 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWM22_RS10995 84d86478a183b611e226448b6efab362 293 Gene3D G3DSA:3.30.420.40 137 266 8.9E-18 T 28-03-2018 CWM22_RS06280 53c3c1b6df897572c51497400d91a41b 272 Pfam PF06970 Replication initiator protein A (RepA) N-terminus 14 88 8.4E-31 T 28-03-2018 IPR010724 Replication initiator A, N-terminal CWM22_RS05480 53c3c1b6df897572c51497400d91a41b 272 Pfam PF06970 Replication initiator protein A (RepA) N-terminus 14 88 8.4E-31 T 28-03-2018 IPR010724 Replication initiator A, N-terminal CWM22_RS10945 0bb201c64d00e75ab7b22ff80f787238 74 Pfam PF00550 Phosphopantetheine attachment site 5 69 8.3E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWM22_RS10945 0bb201c64d00e75ab7b22ff80f787238 74 SUPERFAMILY SSF47336 3 72 6.54E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWM22_RS10945 0bb201c64d00e75ab7b22ff80f787238 74 Hamap MF_01217 Acyl carrier protein [acpP]. 2 73 17.586 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWM22_RS10945 0bb201c64d00e75ab7b22ff80f787238 74 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 32 72 3.0E-15 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWM22_RS10945 0bb201c64d00e75ab7b22ff80f787238 74 Gene3D G3DSA:1.10.1200.10 1 74 7.0E-20 T 28-03-2018 CWM22_RS13020 5a0ddf7d4b8c678997557741614b3f3e 153 Pfam PF04397 LytTr DNA-binding domain 57 151 2.1E-14 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWM22_RS13020 5a0ddf7d4b8c678997557741614b3f3e 153 SMART SM00850 56 152 3.0E-20 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWM22_RS13020 5a0ddf7d4b8c678997557741614b3f3e 153 Gene3D G3DSA:2.40.50.40 46 115 6.2E-8 T 28-03-2018 CWM22_RS13020 5a0ddf7d4b8c678997557741614b3f3e 153 Gene3D G3DSA:2.20.25.10 119 152 8.0E-5 T 28-03-2018 CWM22_RS02820 4287b6bb7c821ba1118dbf82c8f0b6de 223 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 222 6.5E-49 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CWM22_RS02820 4287b6bb7c821ba1118dbf82c8f0b6de 223 SUPERFAMILY SSF51419 1 222 4.07E-69 T 28-03-2018 IPR029066 PLP-binding barrel CWM22_RS02820 4287b6bb7c821ba1118dbf82c8f0b6de 223 PIRSF PIRSF004848 2 223 1.6E-64 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CWM22_RS02820 4287b6bb7c821ba1118dbf82c8f0b6de 223 Pfam PF01168 Alanine racemase, N-terminal domain 7 222 2.3E-18 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWM22_RS02820 4287b6bb7c821ba1118dbf82c8f0b6de 223 Gene3D G3DSA:3.20.20.10 2 223 6.6E-54 T 28-03-2018 IPR029066 PLP-binding barrel CWM22_RS10920 b03128bd7530bb064683c8954ed9b01b 158 Gene3D G3DSA:2.40.50.100 115 158 1.4E-17 T 28-03-2018 CWM22_RS10920 b03128bd7530bb064683c8954ed9b01b 158 Gene3D G3DSA:3.90.1170.30 35 114 2.1E-4 T 28-03-2018 CWM22_RS10920 b03128bd7530bb064683c8954ed9b01b 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 119 132 4.5E-14 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWM22_RS10920 b03128bd7530bb064683c8954ed9b01b 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 104 118 4.5E-14 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWM22_RS10920 b03128bd7530bb064683c8954ed9b01b 158 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 87 100 4.5E-14 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWM22_RS10920 b03128bd7530bb064683c8954ed9b01b 158 Pfam PF00364 Biotin-requiring enzyme 85 157 3.4E-19 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWM22_RS10920 b03128bd7530bb064683c8954ed9b01b 158 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 114 131 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWM22_RS10920 b03128bd7530bb064683c8954ed9b01b 158 SUPERFAMILY SSF51230 84 157 4.06E-22 T 28-03-2018 IPR011053 Single hybrid motif CWM22_RS10920 b03128bd7530bb064683c8954ed9b01b 158 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 158 2.1E-39 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWM22_RS11700 1ba6716b046821783cb998d06a8da967 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.3E-36 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11700 1ba6716b046821783cb998d06a8da967 89 Pfam PF00312 Ribosomal protein S15 8 88 1.0E-33 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS11700 1ba6716b046821783cb998d06a8da967 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.773 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11700 1ba6716b046821783cb998d06a8da967 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 2.0E-38 T 28-03-2018 CWM22_RS11700 1ba6716b046821783cb998d06a8da967 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS11700 1ba6716b046821783cb998d06a8da967 89 Gene3D G3DSA:1.10.287.10 2 89 5.0E-32 T 28-03-2018 CWM22_RS11700 1ba6716b046821783cb998d06a8da967 89 SUPERFAMILY SSF47060 3 89 6.77E-34 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CWM22_RS11700 1ba6716b046821783cb998d06a8da967 89 SMART SM01387 8 88 3.7E-44 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 SMART SM00388 236 303 4.2E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 SUPERFAMILY SSF47384 221 304 2.94E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 SUPERFAMILY SSF55874 293 456 1.44E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 302 7.4E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 SMART SM00387 348 458 1.4E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 Gene3D G3DSA:3.30.565.10 298 458 1.4E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 Pfam PF00672 HAMP domain 178 223 2.6E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 456 5.8E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 SMART SM00304 176 228 5.8E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 Gene3D G3DSA:1.10.287.130 219 297 8.9E-15 T 28-03-2018 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 SUPERFAMILY SSF158472 178 225 2.22E-8 T 28-03-2018 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS13310 a1d03b68da1e03fedde03fdabe3b6aef 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 1.5E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWM22_RS02550 aeefc36295cec1ff19a0bc1f8648120a 180 Gene3D G3DSA:3.30.160.100 2 100 1.4E-26 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWM22_RS02550 aeefc36295cec1ff19a0bc1f8648120a 180 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 96 2.5E-26 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWM22_RS02550 aeefc36295cec1ff19a0bc1f8648120a 180 SUPERFAMILY SSF69754 4 112 1.2E-29 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWM22_RS02550 aeefc36295cec1ff19a0bc1f8648120a 180 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 3 102 3.9E-28 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWM22_RS02550 aeefc36295cec1ff19a0bc1f8648120a 180 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 179 24.296 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CWM22_RS02550 aeefc36295cec1ff19a0bc1f8648120a 180 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 120 175 4.4E-25 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CWM22_RS04425 7643dc52794719258e404f9a494674cc 774 SUPERFAMILY SSF53448 477 705 1.77E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04425 7643dc52794719258e404f9a494674cc 774 Gene3D G3DSA:3.90.550.10 272 457 1.8E-8 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04425 7643dc52794719258e404f9a494674cc 774 Pfam PF01501 Glycosyl transferase family 8 7 242 1.6E-34 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CWM22_RS04425 7643dc52794719258e404f9a494674cc 774 Pfam PF00535 Glycosyl transferase family 2 479 604 4.4E-35 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS04425 7643dc52794719258e404f9a494674cc 774 Gene3D G3DSA:3.90.550.10 6 271 5.2E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04425 7643dc52794719258e404f9a494674cc 774 Gene3D G3DSA:3.90.550.10 476 707 3.7E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04425 7643dc52794719258e404f9a494674cc 774 SUPERFAMILY SSF53448 272 472 4.58E-8 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04425 7643dc52794719258e404f9a494674cc 774 SUPERFAMILY SSF53448 6 258 1.21E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS11680 707d6e7e08534581916a4830bd71e606 286 SUPERFAMILY SSF55729 5 277 3.91E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS11680 707d6e7e08534581916a4830bd71e606 286 Pfam PF13673 Acetyltransferase (GNAT) domain 47 104 9.4E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS11680 707d6e7e08534581916a4830bd71e606 286 Pfam PF13673 Acetyltransferase (GNAT) domain 170 277 6.6E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS11680 707d6e7e08534581916a4830bd71e606 286 Gene3D G3DSA:3.40.630.30 5 115 1.6E-8 T 28-03-2018 CWM22_RS11680 707d6e7e08534581916a4830bd71e606 286 Gene3D G3DSA:3.40.630.30 144 285 3.3E-20 T 28-03-2018 CWM22_RS03945 54037dc59d86a80e4bc724b8239486d4 114 Gene3D G3DSA:1.10.10.10 1 43 9.9E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12220 00615d369f8f4fdfe7b0d1f850048b6a 270 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 54 236 9.9E-54 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CWM22_RS12220 00615d369f8f4fdfe7b0d1f850048b6a 270 Pfam PF02096 60Kd inner membrane protein 55 236 1.0E-49 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWM22_RS12220 00615d369f8f4fdfe7b0d1f850048b6a 270 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 240 29.82 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 Pfam PF00591 Glycosyl transferase family, a/b domain 78 302 2.6E-38 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 SMART SM00941 338 411 2.0E-25 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 Gene3D G3DSA:3.40.1030.10 68 330 3.8E-88 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 SUPERFAMILY SSF47648 1 69 7.59E-23 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 SUPERFAMILY SSF54680 327 421 9.81E-25 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 SUPERFAMILY SSF52418 69 322 6.28E-86 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 410 2.9E-169 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 Gene3D G3DSA:1.20.970.10 1 66 2.3E-25 T 28-03-2018 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 341 410 9.8E-24 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 Gene3D G3DSA:3.90.1170.30 331 416 7.5E-23 T 28-03-2018 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 PIRSF PIRSF000478 1 425 2.7E-158 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS05100 d83525d2137c01c1211c21a09523e11d 425 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 1.3E-21 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Gene3D G3DSA:2.20.230.10 590 672 2.5E-16 T 28-03-2018 CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Gene3D G3DSA:2.20.230.10 429 513 1.4E-14 T 28-03-2018 CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Pfam PF00188 Cysteine-rich secretory protein family 813 928 2.3E-4 T 28-03-2018 IPR014044 CAP domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Gene3D G3DSA:2.20.230.10 514 589 3.9E-17 T 28-03-2018 CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Gene3D G3DSA:2.20.230.10 352 426 1.1E-14 T 28-03-2018 CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Gene3D G3DSA:2.20.230.10 673 747 1.1E-12 T 28-03-2018 CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Pfam PF07501 G5 domain 436 508 1.3E-13 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Pfam PF07501 G5 domain 676 746 3.2E-12 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Pfam PF07501 G5 domain 594 667 9.0E-14 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Pfam PF07501 G5 domain 357 424 5.6E-13 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Pfam PF07501 G5 domain 515 588 5.7E-15 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 Gene3D G3DSA:3.40.33.10 802 949 4.0E-5 T 28-03-2018 IPR014044 CAP domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 SMART SM01208 669 747 1.8E-13 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 SMART SM01208 430 509 9.3E-17 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 SMART SM01208 590 668 1.2E-16 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 SMART SM01208 512 589 4.8E-20 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 SMART SM01208 351 428 1.8E-13 T 28-03-2018 IPR011098 G5 domain CWM22_RS11050 8a3581f0366ded695ce321cfcab73d03 966 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 97 126 2.1E-4 T 28-03-2018 CWM22_RS00980 52dce59f7c1699e72e71a68b8fb9eae8 207 Pfam PF14794 Domain of unknown function (DUF4479) 22 91 1.8E-28 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CWM22_RS00980 52dce59f7c1699e72e71a68b8fb9eae8 207 SUPERFAMILY SSF50249 94 199 1.25E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS00980 52dce59f7c1699e72e71a68b8fb9eae8 207 Gene3D G3DSA:3.30.1940.10 23 90 8.1E-27 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CWM22_RS00980 52dce59f7c1699e72e71a68b8fb9eae8 207 Gene3D G3DSA:2.40.50.140 91 204 4.3E-33 T 28-03-2018 CWM22_RS00980 52dce59f7c1699e72e71a68b8fb9eae8 207 Pfam PF01588 Putative tRNA binding domain 96 197 2.4E-18 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CWM22_RS01100 fa10d3e220b7f13027fc6ed43abcdb6b 227 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 204 2.2E-48 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CWM22_RS01100 fa10d3e220b7f13027fc6ed43abcdb6b 227 SUPERFAMILY SSF53067 1 100 2.16E-26 T 28-03-2018 CWM22_RS01100 fa10d3e220b7f13027fc6ed43abcdb6b 227 Pfam PF00814 Glycoprotease family 31 142 2.3E-27 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01100 fa10d3e220b7f13027fc6ed43abcdb6b 227 SUPERFAMILY SSF53067 105 202 2.63E-9 T 28-03-2018 CWM22_RS01100 fa10d3e220b7f13027fc6ed43abcdb6b 227 Gene3D G3DSA:3.30.420.40 1 136 6.1E-33 T 28-03-2018 CWM22_RS07740 28a6f57d82abcb98c9518a81a4274824 724 Gene3D G3DSA:3.40.720.10 247 567 4.8E-32 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWM22_RS07740 28a6f57d82abcb98c9518a81a4274824 724 PIRSF PIRSF005091 1 646 4.4E-163 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like CWM22_RS07740 28a6f57d82abcb98c9518a81a4274824 724 SUPERFAMILY SSF53649 252 645 1.64E-64 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWM22_RS07740 28a6f57d82abcb98c9518a81a4274824 724 Pfam PF00884 Sulfatase 254 557 3.7E-30 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CWM22_RS08890 6033d7d0b1dc8c9b5148da7558691a20 690 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 680 2.8E-68 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWM22_RS08890 6033d7d0b1dc8c9b5148da7558691a20 690 Gene3D G3DSA:3.40.710.10 319 690 8.8E-62 T 28-03-2018 CWM22_RS08890 6033d7d0b1dc8c9b5148da7558691a20 690 Gene3D G3DSA:3.90.1310.10 32 318 7.7E-28 T 28-03-2018 CWM22_RS08890 6033d7d0b1dc8c9b5148da7558691a20 690 SUPERFAMILY SSF56519 58 121 1.83E-28 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWM22_RS08890 6033d7d0b1dc8c9b5148da7558691a20 690 SUPERFAMILY SSF56519 188 318 1.83E-28 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWM22_RS08890 6033d7d0b1dc8c9b5148da7558691a20 690 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 301 1.2E-31 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWM22_RS08890 6033d7d0b1dc8c9b5148da7558691a20 690 SUPERFAMILY SSF56601 319 686 8.25E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS02220 ded8355aae5792b0b3553286024db07d 209 Pfam PF03932 CutC family 1 206 8.2E-63 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CWM22_RS02220 ded8355aae5792b0b3553286024db07d 209 SUPERFAMILY SSF110395 1 208 2.09E-55 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CWM22_RS02220 ded8355aae5792b0b3553286024db07d 209 Gene3D G3DSA:3.20.20.380 1 209 7.4E-68 T 28-03-2018 CWM22_RS11645 b1f76366326bde27706240476388ba37 428 Gene3D G3DSA:1.50.10.10 6 428 1.3E-161 T 28-03-2018 CWM22_RS11645 b1f76366326bde27706240476388ba37 428 SMART SM01149 22 420 1.8E-277 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CWM22_RS11645 b1f76366326bde27706240476388ba37 428 PIRSF PIRSF028846 1 428 1.5E-206 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CWM22_RS11645 b1f76366326bde27706240476388ba37 428 Pfam PF06824 Metal-independent alpha-mannosidase (GH125) 24 419 2.2E-150 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CWM22_RS11645 b1f76366326bde27706240476388ba37 428 SUPERFAMILY SSF48208 3 425 2.67E-176 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CWM22_RS06220 b19ac3c0ab6130a312cb918f510f074c 214 SMART SM01007 8 184 2.0E-61 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWM22_RS06220 b19ac3c0ab6130a312cb918f510f074c 214 SUPERFAMILY SSF53639 3 213 5.49E-67 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWM22_RS06220 b19ac3c0ab6130a312cb918f510f074c 214 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 183 1.3E-47 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWM22_RS06220 b19ac3c0ab6130a312cb918f510f074c 214 Gene3D G3DSA:3.40.225.10 3 214 3.8E-65 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWM22_RS04005 ac740cbd7bad2f08301cdb4c368b236f 196 Pfam PF07852 Protein of unknown function (DUF1642) 69 195 1.5E-26 T 28-03-2018 IPR012865 Protein of unknown function DUF1642 CWM22_RS06020 8a80fc2b216c8f2efe9b5569e6755f8f 259 SUPERFAMILY SSF53098 60 254 6.37E-63 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS06020 8a80fc2b216c8f2efe9b5569e6755f8f 259 Gene3D G3DSA:3.30.420.10 47 259 5.2E-66 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS06020 8a80fc2b216c8f2efe9b5569e6755f8f 259 Hamap MF_00052_B Ribonuclease HII [rnhB]. 71 249 34.016 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 CWM22_RS06020 8a80fc2b216c8f2efe9b5569e6755f8f 259 Pfam PF01351 Ribonuclease HII 73 247 6.9E-34 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CWM22_RS05180 9de9d51947b03570748a3ba52f25702b 598 SUPERFAMILY SSF51735 139 266 7.48E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS05180 9de9d51947b03570748a3ba52f25702b 598 Pfam PF13727 CoA-binding domain 71 231 2.4E-12 T 28-03-2018 CWM22_RS05180 9de9d51947b03570748a3ba52f25702b 598 SUPERFAMILY SSF51735 278 541 9.56E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS05180 9de9d51947b03570748a3ba52f25702b 598 Gene3D G3DSA:3.40.50.720 273 598 1.3E-66 T 28-03-2018 CWM22_RS05180 9de9d51947b03570748a3ba52f25702b 598 Pfam PF02719 Polysaccharide biosynthesis protein 280 561 1.8E-123 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CWM22_RS05180 9de9d51947b03570748a3ba52f25702b 598 Gene3D G3DSA:3.40.50.720 135 261 3.4E-29 T 28-03-2018 CWM22_RS12485 bb3facb1d8d7ed7f8051cc1ddd3ad098 363 SUPERFAMILY SSF56281 218 327 2.18E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS12485 bb3facb1d8d7ed7f8051cc1ddd3ad098 363 SUPERFAMILY SSF56281 165 189 2.18E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS12485 bb3facb1d8d7ed7f8051cc1ddd3ad098 363 SUPERFAMILY SSF56281 100 134 2.18E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS12485 bb3facb1d8d7ed7f8051cc1ddd3ad098 363 SUPERFAMILY SSF56281 40 63 2.18E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS12485 bb3facb1d8d7ed7f8051cc1ddd3ad098 363 Gene3D G3DSA:3.60.15.10 1 346 1.4E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS12485 bb3facb1d8d7ed7f8051cc1ddd3ad098 363 Pfam PF13483 Beta-lactamase superfamily domain 42 290 1.4E-11 T 28-03-2018 CWM22_RS01485 0300c1247715e24a33936c516edd83e8 444 PRINTS PR00175 Sodium/alanine symporter signature 87 109 3.2E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWM22_RS01485 0300c1247715e24a33936c516edd83e8 444 PRINTS PR00175 Sodium/alanine symporter signature 349 371 3.2E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWM22_RS01485 0300c1247715e24a33936c516edd83e8 444 PRINTS PR00175 Sodium/alanine symporter signature 304 322 3.2E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWM22_RS01485 0300c1247715e24a33936c516edd83e8 444 PRINTS PR00175 Sodium/alanine symporter signature 408 428 3.2E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWM22_RS01485 0300c1247715e24a33936c516edd83e8 444 PRINTS PR00175 Sodium/alanine symporter signature 181 199 3.2E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWM22_RS01485 0300c1247715e24a33936c516edd83e8 444 PRINTS PR00175 Sodium/alanine symporter signature 209 228 3.2E-55 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWM22_RS01485 0300c1247715e24a33936c516edd83e8 444 Pfam PF01235 Sodium:alanine symporter family 48 444 3.5E-146 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWM22_RS01485 0300c1247715e24a33936c516edd83e8 444 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 439 5.8E-158 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWM22_RS01485 0300c1247715e24a33936c516edd83e8 444 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 87 102 - T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWM22_RS03225 0ce3cdf755b7e444419f02b2e35a09ad 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 221 4.2E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS03225 0ce3cdf755b7e444419f02b2e35a09ad 227 SMART SM00448 2 112 5.0E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS03225 0ce3cdf755b7e444419f02b2e35a09ad 227 Pfam PF00072 Response regulator receiver domain 4 113 8.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS03225 0ce3cdf755b7e444419f02b2e35a09ad 227 SUPERFAMILY SSF52172 1 183 1.39E-35 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS03225 0ce3cdf755b7e444419f02b2e35a09ad 227 Gene3D G3DSA:3.40.50.2300 1 122 2.2E-31 T 28-03-2018 CWM22_RS03225 0ce3cdf755b7e444419f02b2e35a09ad 227 Gene3D G3DSA:1.10.10.10 123 226 1.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03225 0ce3cdf755b7e444419f02b2e35a09ad 227 SMART SM00862 146 222 2.9E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS05300 a3585a7e7290be05e8d3d5eed264c311 530 Pfam PF14264 Glucosyl transferase GtrII 77 373 6.6E-35 T 28-03-2018 IPR025686 Glucosyl transferase II CWM22_RS09305 4f6dce129d29a06bc11ee5941b547fc0 291 Gene3D G3DSA:1.10.3100.10 2 121 2.3E-15 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS09305 4f6dce129d29a06bc11ee5941b547fc0 291 SMART SM00530 8 62 7.6E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS09305 4f6dce129d29a06bc11ee5941b547fc0 291 SUPERFAMILY SSF48452 198 281 1.99E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS09305 4f6dce129d29a06bc11ee5941b547fc0 291 Pfam PF01381 Helix-turn-helix 10 62 1.0E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS09305 4f6dce129d29a06bc11ee5941b547fc0 291 SUPERFAMILY SSF47413 6 63 5.36E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS09305 4f6dce129d29a06bc11ee5941b547fc0 291 Gene3D G3DSA:1.25.40.10 187 288 6.9E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS12410 23781c04618d058412dd740a1d26fcee 594 Gene3D G3DSA:3.40.50.300 345 592 1.0E-69 T 28-03-2018 CWM22_RS12410 23781c04618d058412dd740a1d26fcee 594 SMART SM00382 380 566 4.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS12410 23781c04618d058412dd740a1d26fcee 594 Pfam PF00664 ABC transporter transmembrane region 20 307 6.2E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS12410 23781c04618d058412dd740a1d26fcee 594 SUPERFAMILY SSF52540 344 591 4.92E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12410 23781c04618d058412dd740a1d26fcee 594 Gene3D G3DSA:1.20.1560.10 1 344 1.2E-63 T 28-03-2018 CWM22_RS12410 23781c04618d058412dd740a1d26fcee 594 Pfam PF00005 ABC transporter 371 520 1.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS12410 23781c04618d058412dd740a1d26fcee 594 SUPERFAMILY SSF90123 5 342 1.19E-64 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS02980 ef335d359a8c930aacf7ce14c7439733 198 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 10 194 7.9E-61 T 28-03-2018 IPR018672 Protein of unknown function DUF2140 CWM22_RS03220 c0bb065fe6754cdb96cdb4db0cbc9503 393 SUPERFAMILY SSF53474 86 242 3.46E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS03220 c0bb065fe6754cdb96cdb4db0cbc9503 393 Gene3D G3DSA:3.40.50.1820 27 299 3.8E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS03220 c0bb065fe6754cdb96cdb4db0cbc9503 393 Pfam PF11187 Protein of unknown function (DUF2974) 85 306 3.4E-86 T 28-03-2018 IPR024499 Protein of unknown function DUF2974 CWM22_RS01105 ae338242793f8fb25a401c511eacf61d 146 SUPERFAMILY SSF55729 14 141 3.26E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS01105 ae338242793f8fb25a401c511eacf61d 146 Pfam PF00583 Acetyltransferase (GNAT) family 33 119 1.7E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS01105 ae338242793f8fb25a401c511eacf61d 146 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 139 3.7E-38 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CWM22_RS01105 ae338242793f8fb25a401c511eacf61d 146 Gene3D G3DSA:3.40.630.30 2 146 4.0E-28 T 28-03-2018 CWM22_RS11875 9106739ee50f74ae75fea516773b4d65 268 Pfam PF01148 Cytidylyltransferase family 7 265 1.8E-72 T 28-03-2018 CWM22_RS11875 9106739ee50f74ae75fea516773b4d65 268 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 227 253 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CWM22_RS02670 01c8d24382fad06653e1abd3db2c8f68 297 Pfam PF03609 PTS system sorbose-specific iic component 3 235 7.7E-61 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CWM22_RS13190 ad9fb9674ea3e748879a40327cdd5808 303 PRINTS PR00069 Aldo-keto reductase signature 183 212 3.1E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS13190 ad9fb9674ea3e748879a40327cdd5808 303 PRINTS PR00069 Aldo-keto reductase signature 231 255 3.1E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS13190 ad9fb9674ea3e748879a40327cdd5808 303 PRINTS PR00069 Aldo-keto reductase signature 99 117 3.1E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWM22_RS13190 ad9fb9674ea3e748879a40327cdd5808 303 SUPERFAMILY SSF51430 3 296 1.7E-71 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWM22_RS13190 ad9fb9674ea3e748879a40327cdd5808 303 Pfam PF00248 Aldo/keto reductase family 13 294 8.2E-49 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWM22_RS13190 ad9fb9674ea3e748879a40327cdd5808 303 Gene3D G3DSA:3.20.20.100 1 301 3.1E-69 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWM22_RS04065 e69a69ac568283f77a668148199ce0ec 410 Pfam PF03237 Terminase-like family 72 232 1.0E-9 T 28-03-2018 CWM22_RS04065 e69a69ac568283f77a668148199ce0ec 410 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 26 393 6.2E-48 T 28-03-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 CWM22_RS04065 e69a69ac568283f77a668148199ce0ec 410 Pfam PF17289 Terminase RNaseH-like domain 253 392 6.7E-6 T 28-03-2018 IPR035421 Terminase, large subunit gp17-like CWM22_RS01170 fadf18a246cfa3994e470b747f331b7f 66 Pfam PF00232 Glycosyl hydrolase family 1 9 46 5.3E-8 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWM22_RS01170 fadf18a246cfa3994e470b747f331b7f 66 SUPERFAMILY SSF51445 6 45 7.87E-9 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS01170 fadf18a246cfa3994e470b747f331b7f 66 Gene3D G3DSA:3.20.20.80 1 61 4.5E-9 T 28-03-2018 CWM22_RS01090 49c5d7159d9918696417c06ac0a82933 378 SUPERFAMILY SSF52743 74 281 1.7E-30 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS01090 49c5d7159d9918696417c06ac0a82933 378 Gene3D G3DSA:3.40.50.200 55 325 2.5E-28 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS01090 49c5d7159d9918696417c06ac0a82933 378 PRINTS PR00723 Subtilisin serine protease family (S8) signature 111 124 5.7E-6 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS01090 49c5d7159d9918696417c06ac0a82933 378 PRINTS PR00723 Subtilisin serine protease family (S8) signature 262 278 5.7E-6 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS01090 49c5d7159d9918696417c06ac0a82933 378 PRINTS PR00723 Subtilisin serine protease family (S8) signature 75 94 5.7E-6 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CWM22_RS01090 49c5d7159d9918696417c06ac0a82933 378 Pfam PF00082 Subtilase family 77 191 4.4E-13 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CWM22_RS01090 49c5d7159d9918696417c06ac0a82933 378 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 115 125 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CWM22_RS01855 4e5443ec3eb838e86cfa1e117b4af51b 88 SUPERFAMILY SSF55021 1 82 9.74E-21 T 28-03-2018 CWM22_RS01855 4e5443ec3eb838e86cfa1e117b4af51b 88 Gene3D G3DSA:3.30.70.260 1 83 1.1E-21 T 28-03-2018 CWM22_RS01855 4e5443ec3eb838e86cfa1e117b4af51b 88 Pfam PF13740 ACT domain 4 75 3.7E-13 T 28-03-2018 CWM22_RS01855 4e5443ec3eb838e86cfa1e117b4af51b 88 Hamap MF_01054 UPF0237 protein . 1 88 24.582 T 28-03-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type CWM22_RS00475 cd92d903125eb8779917e956b4b922fb 105 Pfam PF06949 Protein of unknown function (DUF1292) 24 104 1.9E-14 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CWM22_RS00475 cd92d903125eb8779917e956b4b922fb 105 Hamap MF_01448 UPF0473 protein . 15 105 21.551 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CWM22_RS10865 315cf8142a3e9ba51a9063c4006b56b1 414 SUPERFAMILY SSF116734 212 413 1.32E-31 T 28-03-2018 CWM22_RS10865 315cf8142a3e9ba51a9063c4006b56b1 414 Pfam PF01420 Type I restriction modification DNA specificity domain 18 195 1.6E-8 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CWM22_RS10865 315cf8142a3e9ba51a9063c4006b56b1 414 SUPERFAMILY SSF116734 7 208 5.07E-33 T 28-03-2018 CWM22_RS10865 315cf8142a3e9ba51a9063c4006b56b1 414 Gene3D G3DSA:3.90.220.20 3 189 5.3E-21 T 28-03-2018 CWM22_RS10865 315cf8142a3e9ba51a9063c4006b56b1 414 Gene3D G3DSA:3.90.220.20 190 398 5.9E-24 T 28-03-2018 CWM22_RS02235 9b24ce848653a60cea1854dfefffb2d1 368 Gene3D G3DSA:3.40.50.300 59 227 2.2E-29 T 28-03-2018 CWM22_RS02235 9b24ce848653a60cea1854dfefffb2d1 368 Pfam PF01926 50S ribosome-binding GTPase 166 230 7.1E-14 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWM22_RS02235 9b24ce848653a60cea1854dfefffb2d1 368 SUPERFAMILY SSF52540 65 275 4.55E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02235 9b24ce848653a60cea1854dfefffb2d1 368 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 368 2.1E-155 T 28-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH CWM22_RS12830 dcb88b384e7092c1a50be4b3cdf09ff0 417 Pfam PF02371 Transposase IS116/IS110/IS902 family 285 370 1.9E-26 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS12830 dcb88b384e7092c1a50be4b3cdf09ff0 417 Pfam PF01548 Transposase 5 161 2.7E-28 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS12830 dcb88b384e7092c1a50be4b3cdf09ff0 417 Gene3D G3DSA:1.10.150.280 100 330 0.0031 T 28-03-2018 CWM22_RS12225 e090658d0226af3d8553d357ea0828eb 119 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 107 3.3E-28 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWM22_RS12225 e090658d0226af3d8553d357ea0828eb 119 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 50 64 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CWM22_RS12225 e090658d0226af3d8553d357ea0828eb 119 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 109 18.78 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWM22_RS12225 e090658d0226af3d8553d357ea0828eb 119 SUPERFAMILY SSF54211 1 111 2.33E-33 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS12225 e090658d0226af3d8553d357ea0828eb 119 Gene3D G3DSA:3.30.230.10 1 113 2.8E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS12225 e090658d0226af3d8553d357ea0828eb 119 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 8 105 4.0E-32 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWM22_RS12225 e090658d0226af3d8553d357ea0828eb 119 Pfam PF00825 Ribonuclease P 1 104 1.5E-31 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWM22_RS02730 abb7edc0506250245cef4c1476c2b4bc 387 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 4 377 3.5E-61 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS02730 abb7edc0506250245cef4c1476c2b4bc 387 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 82 94 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CWM22_RS02730 abb7edc0506250245cef4c1476c2b4bc 387 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 378 1.2E-67 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02730 abb7edc0506250245cef4c1476c2b4bc 387 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 360 378 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CWM22_RS02730 abb7edc0506250245cef4c1476c2b4bc 387 SUPERFAMILY SSF53335 1 379 1.2E-87 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02730 abb7edc0506250245cef4c1476c2b4bc 387 Gene3D G3DSA:3.40.50.150 1 278 2.9E-62 T 28-03-2018 CWM22_RS02730 abb7edc0506250245cef4c1476c2b4bc 387 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 3 19 3.6E-19 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS02730 abb7edc0506250245cef4c1476c2b4bc 387 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 175 188 3.6E-19 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS02730 abb7edc0506250245cef4c1476c2b4bc 387 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 119 133 3.6E-19 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CWM22_RS04095 2d1c7c36f5ab4116ed6f7b4009b47d78 338 SMART SM00495 292 337 4.5E-4 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CWM22_RS04095 2d1c7c36f5ab4116ed6f7b4009b47d78 338 ProDom PD566665 CAPSID GP34 MAIN MAJOR LJ928 STRUCTURAL PROPHAGE GP34-LIKE LIN2390 DIRECT 59 276 9.0E-4 T 28-03-2018 CWM22_RS04095 2d1c7c36f5ab4116ed6f7b4009b47d78 338 Gene3D G3DSA:2.10.10.20 289 337 3.4E-8 T 28-03-2018 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 Gene3D G3DSA:3.40.50.620 132 248 3.5E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 Gene3D G3DSA:3.40.50.620 5 131 8.2E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 482 1.2E-169 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 8.1E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 206 8.1E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 8.1E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 8.1E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 212 220 8.1E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 481 32.166 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 Gene3D G3DSA:1.10.1160.10 250 336 1.0E-29 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 SUPERFAMILY SSF48163 320 481 9.81E-41 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 326 8.0E-114 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 SUPERFAMILY SSF52374 5 318 2.68E-104 T 28-03-2018 CWM22_RS12260 32fe2cd85127cd212b07b17465e3a1fe 484 Gene3D G3DSA:1.10.10.350 381 482 1.3E-25 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWM22_RS03515 f5616adb0d1ef153928c26c6fdf53b33 283 SUPERFAMILY SSF82549 3 282 1.07E-66 T 28-03-2018 CWM22_RS03515 f5616adb0d1ef153928c26c6fdf53b33 283 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 279 1.0E-52 T 28-03-2018 IPR003797 DegV CWM22_RS03515 f5616adb0d1ef153928c26c6fdf53b33 283 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 273 1.0E-66 T 28-03-2018 IPR003797 DegV CWM22_RS03515 f5616adb0d1ef153928c26c6fdf53b33 283 Gene3D G3DSA:3.40.50.10440 57 153 2.2E-24 T 28-03-2018 CWM22_RS03515 f5616adb0d1ef153928c26c6fdf53b33 283 Gene3D G3DSA:2.20.28.50 30 56 1.3E-13 T 28-03-2018 CWM22_RS03515 f5616adb0d1ef153928c26c6fdf53b33 283 Gene3D G3DSA:3.30.1180.10 156 280 1.7E-20 T 28-03-2018 CWM22_RS11530 c187cfa39f30fb1a9b5d0a21fd32d819 231 Gene3D G3DSA:3.40.50.150 14 222 6.5E-9 T 28-03-2018 CWM22_RS11530 c187cfa39f30fb1a9b5d0a21fd32d819 231 SUPERFAMILY SSF53335 13 148 2.7E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS03055 8e95bddb82ba96e2b06c8467edbfefc1 89 Pfam PF06961 Protein of unknown function (DUF1294) 15 69 1.2E-22 T 28-03-2018 IPR010718 Protein of unknown function DUF1294 CWM22_RS07935 ded776b501ab792b823e371ebeeed438 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 3.7E-67 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CWM22_RS07935 ded776b501ab792b823e371ebeeed438 170 Gene3D G3DSA:3.40.50.2020 1 169 1.5E-41 T 28-03-2018 CWM22_RS07935 ded776b501ab792b823e371ebeeed438 170 Pfam PF00156 Phosphoribosyl transferase domain 37 166 1.5E-16 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWM22_RS07935 ded776b501ab792b823e371ebeeed438 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.03 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CWM22_RS07935 ded776b501ab792b823e371ebeeed438 170 SUPERFAMILY SSF53271 2 167 3.12E-50 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS07765 11ea2d8652150ac6e20dc5a39ae01271 225 Pfam PF02224 Cytidylate kinase 6 220 5.8E-73 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWM22_RS07765 11ea2d8652150ac6e20dc5a39ae01271 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 3 218 2.5E-76 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWM22_RS07765 11ea2d8652150ac6e20dc5a39ae01271 225 Hamap MF_00238 Cytidylate kinase [cmk]. 4 223 32.99 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWM22_RS07765 11ea2d8652150ac6e20dc5a39ae01271 225 Gene3D G3DSA:3.40.50.300 1 223 8.6E-52 T 28-03-2018 CWM22_RS07765 11ea2d8652150ac6e20dc5a39ae01271 225 SUPERFAMILY SSF52540 1 222 3.24E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12065 6be56b556b7afa84fe4736ce942504d0 270 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 269 1.1E-124 T 28-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CWM22_RS12065 6be56b556b7afa84fe4736ce942504d0 270 SUPERFAMILY SSF46785 2 73 1.18E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12065 6be56b556b7afa84fe4736ce942504d0 270 Gene3D G3DSA:1.10.10.10 1 73 1.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12065 6be56b556b7afa84fe4736ce942504d0 270 Gene3D G3DSA:3.40.50.2020 74 270 2.1E-29 T 28-03-2018 CWM22_RS12065 6be56b556b7afa84fe4736ce942504d0 270 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 2.2E-29 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CWM22_RS12065 6be56b556b7afa84fe4736ce942504d0 270 Pfam PF00156 Phosphoribosyl transferase domain 106 261 6.3E-27 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWM22_RS12065 6be56b556b7afa84fe4736ce942504d0 270 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 10 73 8.0E-26 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CWM22_RS12065 6be56b556b7afa84fe4736ce942504d0 270 SUPERFAMILY SSF53271 94 239 1.35E-35 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS09280 d7e1bff279babb878a91545508d19b86 111 SUPERFAMILY SSF47413 7 72 1.97E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS09280 d7e1bff279babb878a91545508d19b86 111 Gene3D G3DSA:1.10.260.40 9 105 1.3E-18 T 28-03-2018 CWM22_RS09280 d7e1bff279babb878a91545508d19b86 111 Pfam PF01381 Helix-turn-helix 14 67 6.4E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS09280 d7e1bff279babb878a91545508d19b86 111 SMART SM00530 13 68 2.1E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS08240 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS11995 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS08870 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS13035 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS06825 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS00305 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS00785 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS09695 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS07680 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS05420 60566f6b0d30b6f1cce5408998e7d77e 116 Pfam PF05717 IS66 Orf2 like protein 10 104 8.9E-38 T 28-03-2018 IPR008878 Transposase IS66, Orf2 CWM22_RS08205 7f77726a036adcb9df870bf851b337bc 301 Pfam PF03773 Predicted permease 13 297 8.4E-70 T 28-03-2018 IPR005524 Predicted permease DUF318 CWM22_RS11400 7244cb240d1914d1cec8048d4f599db5 257 SUPERFAMILY SSF52540 3 231 1.15E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS11400 7244cb240d1914d1cec8048d4f599db5 257 SMART SM00382 28 230 3.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS11400 7244cb240d1914d1cec8048d4f599db5 257 Pfam PF00005 ABC transporter 19 171 7.2E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS11400 7244cb240d1914d1cec8048d4f599db5 257 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 243 5.9E-110 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CWM22_RS11400 7244cb240d1914d1cec8048d4f599db5 257 Gene3D G3DSA:3.40.50.300 1 249 7.7E-44 T 28-03-2018 CWM22_RS11400 7244cb240d1914d1cec8048d4f599db5 257 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS04405 42a0685dc519e5bc109a1f3ac2497f41 298 SUPERFAMILY SSF53448 4 224 6.25E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04405 42a0685dc519e5bc109a1f3ac2497f41 298 Pfam PF00535 Glycosyl transferase family 2 7 164 2.7E-37 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS04405 42a0685dc519e5bc109a1f3ac2497f41 298 Gene3D G3DSA:3.90.550.10 1 295 8.9E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS10250 d119f26a985cfb0409f78c94dc81df10 391 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 388 48.818 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWM22_RS10250 d119f26a985cfb0409f78c94dc81df10 391 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 5 387 6.8E-184 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWM22_RS10250 d119f26a985cfb0409f78c94dc81df10 391 Gene3D G3DSA:3.40.50.1100 193 391 4.4E-35 T 28-03-2018 CWM22_RS10250 d119f26a985cfb0409f78c94dc81df10 391 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 51 375 4.2E-45 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWM22_RS10250 d119f26a985cfb0409f78c94dc81df10 391 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 79 93 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWM22_RS10250 d119f26a985cfb0409f78c94dc81df10 391 PIRSF PIRSF001413 1 391 1.9E-158 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWM22_RS10250 d119f26a985cfb0409f78c94dc81df10 391 SUPERFAMILY SSF53686 3 387 1.1E-135 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWM22_RS10250 d119f26a985cfb0409f78c94dc81df10 391 Gene3D G3DSA:3.40.50.1100 66 192 2.9E-34 T 28-03-2018 CWM22_RS10250 d119f26a985cfb0409f78c94dc81df10 391 Gene3D G3DSA:3.40.50.1100 7 65 5.4E-7 T 28-03-2018 CWM22_RS10105 6c92cac484ee0e33b44fb22bca0d58a4 71 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 19 66 6.2E-11 T 28-03-2018 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0003713|GO:0006355 CWM22_RS10105 6c92cac484ee0e33b44fb22bca0d58a4 71 PIRSF PIRSF037246 1 71 1.3E-37 T 28-03-2018 IPR017154 Uncharacterised conserved protein UCP037246 CWM22_RS05555 9046b59055950ca24090541ae435f4d2 287 SUPERFAMILY SSF52540 30 178 1.6E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05555 9046b59055950ca24090541ae435f4d2 287 Pfam PF06414 Zeta toxin 25 214 1.4E-47 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 CWM22_RS05555 9046b59055950ca24090541ae435f4d2 287 Gene3D G3DSA:3.40.50.300 4 284 5.9E-34 T 28-03-2018 CWM22_RS08320 5a10373f22904588c0b834bd6b28c7da 397 SMART SM01329 19 389 4.4E-174 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWM22_RS08320 5a10373f22904588c0b834bd6b28c7da 397 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 392 1.5E-175 T 28-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CWM22_RS08320 5a10373f22904588c0b834bd6b28c7da 397 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 20 387 6.0E-108 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWM22_RS08320 5a10373f22904588c0b834bd6b28c7da 397 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 279 298 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CWM22_RS08320 5a10373f22904588c0b834bd6b28c7da 397 SUPERFAMILY SSF53659 4 391 3.84E-133 T 28-03-2018 CWM22_RS08320 5a10373f22904588c0b834bd6b28c7da 397 Gene3D G3DSA:3.40.718.10 2 397 1.1E-127 T 28-03-2018 CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 8.0E-16 T 28-03-2018 CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 SUPERFAMILY SSF46906 67 139 6.28E-28 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 Gene3D G3DSA:3.30.1550.10 3 71 5.9E-35 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 Gene3D G3DSA:1.10.10.250 72 140 1.5E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 SMART SM00649 9 140 2.1E-87 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 SUPERFAMILY SSF54747 1 84 1.44E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.467 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 4.1E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 4.8E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CWM22_RS03385 3ae1aa66aeaa645272c56f59dc73fb1e 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 6.3E-64 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS02195 3cd1ac123801149449e8f4c1ab856d19 35 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 1 35 2.1E-10 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) CWM22_RS07715 6b5a788a856d75f780187d641bbad1ea 112 Gene3D G3DSA:1.20.1500.10 4 109 4.0E-24 T 28-03-2018 IPR023378 YheA/YmcA-like domain CWM22_RS07715 6b5a788a856d75f780187d641bbad1ea 112 SUPERFAMILY SSF158622 4 111 1.7E-29 T 28-03-2018 IPR023378 YheA/YmcA-like domain CWM22_RS07715 6b5a788a856d75f780187d641bbad1ea 112 Hamap MF_01526 UPF0342 protein . 2 112 15.594 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CWM22_RS07715 6b5a788a856d75f780187d641bbad1ea 112 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 5 109 1.1E-20 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CWM22_RS01495 6480af85d0bd2ecc8e45f20eae5cefe4 175 Gene3D G3DSA:2.60.40.1240 54 174 1.4E-11 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CWM22_RS01495 6480af85d0bd2ecc8e45f20eae5cefe4 175 Pfam PF11611 Domain of unknown function (DUF4352) 55 168 1.9E-8 T 28-03-2018 IPR029051 Domain of unknown function DUF4352 CWM22_RS09955 ee05414bde3a5eba197fa345d5f0cb24 138 Pfam PF05154 TM2 domain 44 92 8.7E-11 T 28-03-2018 IPR007829 TM2 domain CWM22_RS04830 a48d5998d06df6833865634f072416de 124 Gene3D G3DSA:1.10.10.10 4 82 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS04830 a48d5998d06df6833865634f072416de 124 SUPERFAMILY SSF46785 4 78 1.05E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS04830 a48d5998d06df6833865634f072416de 124 SMART SM00345 15 74 3.5E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS04830 a48d5998d06df6833865634f072416de 124 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 3.0E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS04830 a48d5998d06df6833865634f072416de 124 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 3.0E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS04830 a48d5998d06df6833865634f072416de 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 4.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWM22_RS06385 9e60d38a923e62022e3cb2fa99438630 592 Gene3D G3DSA:3.40.1800.10 516 591 0.001 T 28-03-2018 CWM22_RS06385 9e60d38a923e62022e3cb2fa99438630 592 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 87 352 8.7E-36 T 28-03-2018 IPR000477 Reverse transcriptase domain CWM22_RS06385 9e60d38a923e62022e3cb2fa99438630 592 SUPERFAMILY SSF56672 46 235 1.56E-46 T 28-03-2018 CWM22_RS06385 9e60d38a923e62022e3cb2fa99438630 592 SUPERFAMILY SSF56672 288 402 1.56E-46 T 28-03-2018 CWM22_RS06385 9e60d38a923e62022e3cb2fa99438630 592 Pfam PF01348 Type II intron maturase 386 463 1.1E-10 T 28-03-2018 IPR024937 Domain X GO:0006397 CWM22_RS06385 9e60d38a923e62022e3cb2fa99438630 592 Gene3D G3DSA:3.30.70.270 116 352 2.1E-40 T 28-03-2018 CWM22_RS12895 65f000d07af3e2ddfefe39b5e18a21da 114 Gene3D G3DSA:1.10.10.10 62 94 0.31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12895 65f000d07af3e2ddfefe39b5e18a21da 114 Gene3D G3DSA:1.10.1220.10 7 61 2.8E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWM22_RS12895 65f000d07af3e2ddfefe39b5e18a21da 114 Gene3D G3DSA:1.10.1220.10 95 114 0.087 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWM22_RS11205 07e290ab58fe722a68de4b54610780bb 322 Pfam PF00676 Dehydrogenase E1 component 15 312 7.7E-85 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CWM22_RS11205 07e290ab58fe722a68de4b54610780bb 322 SUPERFAMILY SSF52518 3 322 5.9E-100 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWM22_RS11205 07e290ab58fe722a68de4b54610780bb 322 Gene3D G3DSA:3.40.50.970 1 322 1.1E-89 T 28-03-2018 CWM22_RS10655 7f60105a909ed3e26b9826964e7a9863 349 Gene3D G3DSA:3.10.520.10 23 337 2.9E-55 T 28-03-2018 CWM22_RS10655 7f60105a909ed3e26b9826964e7a9863 349 Pfam PF02424 ApbE family 43 320 1.7E-82 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CWM22_RS10655 7f60105a909ed3e26b9826964e7a9863 349 PIRSF PIRSF006268 1 342 1.3E-105 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CWM22_RS10655 7f60105a909ed3e26b9826964e7a9863 349 SUPERFAMILY SSF143631 35 337 4.53E-92 T 28-03-2018 IPR003374 ApbE-like domain CWM22_RS02945 a8ef9f4fdb5f34d3a92bda18f504411c 71 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 7 67 14.073 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWM22_RS02945 a8ef9f4fdb5f34d3a92bda18f504411c 71 Gene3D G3DSA:1.10.287.1040 5 69 6.8E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWM22_RS02945 a8ef9f4fdb5f34d3a92bda18f504411c 71 PIRSF PIRSF006488 1 71 1.0E-17 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWM22_RS02945 a8ef9f4fdb5f34d3a92bda18f504411c 71 Pfam PF02609 Exonuclease VII small subunit 8 57 1.5E-17 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWM22_RS02945 a8ef9f4fdb5f34d3a92bda18f504411c 71 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 6 49 2.0E-17 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWM22_RS02945 a8ef9f4fdb5f34d3a92bda18f504411c 71 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 7 62 3.2E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWM22_RS02945 a8ef9f4fdb5f34d3a92bda18f504411c 71 SUPERFAMILY SSF116842 2 69 6.02E-18 T 28-03-2018 CWM22_RS11380 36b474893cd437d2d64e2644e4c1bee3 471 Pfam PF01458 Uncharacterized protein family (UPF0051) 217 442 1.4E-73 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CWM22_RS11380 36b474893cd437d2d64e2644e4c1bee3 471 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 15 462 6.5E-222 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CWM22_RS11380 36b474893cd437d2d64e2644e4c1bee3 471 SUPERFAMILY SSF101960 38 468 5.89E-140 T 28-03-2018 CWM22_RS10145 3dcc7959bc955c451af22aa163ab6562 565 SUPERFAMILY SSF55486 33 559 3.02E-108 T 28-03-2018 CWM22_RS10145 3dcc7959bc955c451af22aa163ab6562 565 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 14 560 1.8E-202 T 28-03-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related CWM22_RS10145 3dcc7959bc955c451af22aa163ab6562 565 Gene3D G3DSA:1.10.1370.10 68 559 7.4E-59 T 28-03-2018 CWM22_RS10145 3dcc7959bc955c451af22aa163ab6562 565 Pfam PF01432 Peptidase family M3 167 548 9.0E-25 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CWM22_RS12350 36212fc04f8b270f859f97a09707bec3 94 TIGRFAM TIGR01653 lactococcin_972: bacteriocin, lactococcin 972 family 9 94 8.4E-17 T 28-03-2018 IPR006540 Bacteriocin, lactococcin 972 CWM22_RS12350 36212fc04f8b270f859f97a09707bec3 94 Pfam PF09683 Bacteriocin (Lactococcin_972) 29 91 1.4E-20 T 28-03-2018 IPR006540 Bacteriocin, lactococcin 972 CWM22_RS02430 f848577fc5f52e5ccb8df0dab5dd4c73 179 PIRSF PIRSF021290 3 176 6.5E-62 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CWM22_RS02430 f848577fc5f52e5ccb8df0dab5dd4c73 179 SUPERFAMILY SSF102405 4 173 8.7E-55 T 28-03-2018 CWM22_RS02430 f848577fc5f52e5ccb8df0dab5dd4c73 179 Pfam PF06908 Protein of unknown function (DUF1273) 6 168 1.1E-60 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CWM22_RS02430 f848577fc5f52e5ccb8df0dab5dd4c73 179 Gene3D G3DSA:3.40.50.450 2 177 1.3E-25 T 28-03-2018 CWM22_RS02430 f848577fc5f52e5ccb8df0dab5dd4c73 179 Hamap MF_01575 UPF0398 protein . 3 174 33.263 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 Pfam PF13291 ACT domain 652 730 2.6E-20 T 28-03-2018 IPR002912 ACT domain CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 SUPERFAMILY SSF81271 376 449 3.05E-20 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 Pfam PF02824 TGS domain 389 448 7.9E-21 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 Gene3D G3DSA:3.30.70.260 652 733 1.0E-9 T 28-03-2018 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 Pfam PF13328 HD domain 30 179 1.3E-48 T 28-03-2018 IPR003607 HD/PDEase domain CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 Gene3D G3DSA:3.30.460.10 196 328 2.0E-42 T 28-03-2018 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 SMART SM00954 239 348 3.6E-61 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 30 730 1.3E-239 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 SUPERFAMILY SSF55021 658 730 5.34E-10 T 28-03-2018 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 SUPERFAMILY SSF109604 8 195 7.53E-75 T 28-03-2018 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 Gene3D G3DSA:3.10.20.30 383 455 4.4E-23 T 28-03-2018 IPR012675 Beta-grasp domain CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 SMART SM00471 45 157 9.8E-10 T 28-03-2018 IPR003607 HD/PDEase domain CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 SUPERFAMILY SSF81301 198 365 2.78E-58 T 28-03-2018 CWM22_RS12750 c3de3bdceaf075d1bad6e4009bf058ab 733 Pfam PF04607 Region found in RelA / SpoT proteins 239 348 4.8E-35 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWM22_RS12345 f7b78b56ece4c09359452dd6f58b0b7b 288 SUPERFAMILY SSF47413 4 64 3.1E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS12345 f7b78b56ece4c09359452dd6f58b0b7b 288 Gene3D G3DSA:1.10.3100.10 4 121 8.8E-13 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS12345 f7b78b56ece4c09359452dd6f58b0b7b 288 SMART SM00530 8 62 5.5E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12345 f7b78b56ece4c09359452dd6f58b0b7b 288 Pfam PF01381 Helix-turn-helix 9 62 4.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS07215 c9d15c28ed9402402a6a6d51588e0aa0 49 Gene3D G3DSA:3.40.630.30 1 45 4.4E-4 T 28-03-2018 CWM22_RS07215 c9d15c28ed9402402a6a6d51588e0aa0 49 Pfam PF00583 Acetyltransferase (GNAT) family 2 44 1.7E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS00495 d68126d32b05f5c3a8a132d870374ab6 208 ProSitePatterns PS00474 Ribosomal protein L3 signature. 100 123 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CWM22_RS00495 d68126d32b05f5c3a8a132d870374ab6 208 Pfam PF00297 Ribosomal protein L3 97 177 8.0E-15 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00495 d68126d32b05f5c3a8a132d870374ab6 208 SUPERFAMILY SSF50447 1 206 9.71E-79 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWM22_RS00495 d68126d32b05f5c3a8a132d870374ab6 208 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 201 1.1E-83 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00495 d68126d32b05f5c3a8a132d870374ab6 208 Gene3D G3DSA:4.10.960.10 59 162 2.1E-32 T 28-03-2018 CWM22_RS00495 d68126d32b05f5c3a8a132d870374ab6 208 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 204 38.65 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS09670 b29262df32dc3013ae3b499113da2e0e 244 Pfam PF10552 ORF6C domain 119 231 2.4E-33 T 28-03-2018 IPR018878 ORF6C domain CWM22_RS09670 b29262df32dc3013ae3b499113da2e0e 244 Pfam PF02498 BRO family, N-terminal domain 19 96 2.9E-17 T 28-03-2018 IPR003497 BRO N-terminal domain CWM22_RS09670 b29262df32dc3013ae3b499113da2e0e 244 SMART SM01040 15 100 5.5E-24 T 28-03-2018 IPR003497 BRO N-terminal domain CWM22_RS11620 9bb9cdabb1c946b2b259efd907ea34de 307 Gene3D G3DSA:1.10.3720.10 74 302 8.7E-37 T 28-03-2018 CWM22_RS11620 9bb9cdabb1c946b2b259efd907ea34de 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 301 2.0E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS11620 9bb9cdabb1c946b2b259efd907ea34de 307 SUPERFAMILY SSF161098 20 306 1.12E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS07980 d2bd3a4c08a65295e4aec7c0867b4307 294 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 5 293 27.553 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CWM22_RS07980 d2bd3a4c08a65295e4aec7c0867b4307 294 SUPERFAMILY SSF52540 1 43 4.22E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07980 d2bd3a4c08a65295e4aec7c0867b4307 294 SUPERFAMILY SSF52540 112 251 4.22E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07980 d2bd3a4c08a65295e4aec7c0867b4307 294 Gene3D G3DSA:3.40.50.300 1 180 4.8E-53 T 28-03-2018 CWM22_RS07980 d2bd3a4c08a65295e4aec7c0867b4307 294 Gene3D G3DSA:1.10.287.890 187 266 3.7E-30 T 28-03-2018 CWM22_RS07980 d2bd3a4c08a65295e4aec7c0867b4307 294 SUPERFAMILY SSF52540 5 138 1.98E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07980 d2bd3a4c08a65295e4aec7c0867b4307 294 Pfam PF01715 IPP transferase 38 269 1.8E-71 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CWM22_RS07980 d2bd3a4c08a65295e4aec7c0867b4307 294 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 5 273 4.4E-74 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CWM22_RS10060 5b9fe2fc7dc4ef52a9fc1e729addea8a 207 PIRSF PIRSF000709 1 173 3.5E-14 T 28-03-2018 CWM22_RS10060 5b9fe2fc7dc4ef52a9fc1e729addea8a 207 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 202 5.9E-50 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS10060 5b9fe2fc7dc4ef52a9fc1e729addea8a 207 SMART SM00855 2 160 2.6E-17 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS10060 5b9fe2fc7dc4ef52a9fc1e729addea8a 207 SUPERFAMILY SSF53254 2 204 2.63E-52 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS10060 5b9fe2fc7dc4ef52a9fc1e729addea8a 207 Gene3D G3DSA:3.40.50.1240 1 207 2.2E-48 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS07350 88401cf158befc1b7cab7b1287c63187 42 Pfam PF13253 Protein of unknown function (DUF4044) 6 38 1.0E-14 T 28-03-2018 IPR025270 Protein of unknown function DUF4044 CWM22_RS03625 e8dd7c4647c2c6a7f473842345bc0abd 306 SUPERFAMILY SSF103481 211 304 1.57E-8 T 28-03-2018 CWM22_RS03625 e8dd7c4647c2c6a7f473842345bc0abd 306 Pfam PF00892 EamA-like transporter family 167 304 4.1E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWM22_RS03625 e8dd7c4647c2c6a7f473842345bc0abd 306 Pfam PF00892 EamA-like transporter family 7 153 1.8E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWM22_RS03625 e8dd7c4647c2c6a7f473842345bc0abd 306 SUPERFAMILY SSF103481 78 157 7.32E-11 T 28-03-2018 CWM22_RS10010 09ab7647f0b47d22251c0ef6cae9de18 320 Pfam PF13791 Sigma factor regulator C-terminal 155 307 4.6E-20 T 28-03-2018 IPR025672 Sigma factor regulator C-terminal domain CWM22_RS10010 09ab7647f0b47d22251c0ef6cae9de18 320 Pfam PF13800 Sigma factor regulator N-terminal 8 88 1.0E-6 T 28-03-2018 IPR029101 Sigma factor regulator, N-terminal CWM22_RS01295 85e28d6f179024aa83229e331d60c038 307 Gene3D G3DSA:2.20.150.10 9 42 1.2E-5 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CWM22_RS01295 85e28d6f179024aa83229e331d60c038 307 PIRSF PIRSF000535 1 306 2.1E-47 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWM22_RS01295 85e28d6f179024aa83229e331d60c038 307 SUPERFAMILY SSF53613 1 283 7.17E-44 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS01295 85e28d6f179024aa83229e331d60c038 307 Pfam PF00294 pfkB family carbohydrate kinase 12 283 5.3E-27 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWM22_RS01295 85e28d6f179024aa83229e331d60c038 307 Gene3D G3DSA:3.40.1190.20 43 303 2.3E-26 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS11330 c95ebd4badc40db76602ecb4ef9fde77 175 SUPERFAMILY SSF55729 5 174 3.32E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS11330 c95ebd4badc40db76602ecb4ef9fde77 175 Pfam PF00583 Acetyltransferase (GNAT) family 40 145 4.6E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS11330 c95ebd4badc40db76602ecb4ef9fde77 175 Gene3D G3DSA:3.40.630.30 2 173 1.8E-32 T 28-03-2018 CWM22_RS12125 b7e5f83b9c26deeb24d36754fb104b2c 530 SMART SM00382 347 525 2.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS12125 b7e5f83b9c26deeb24d36754fb104b2c 530 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS12125 b7e5f83b9c26deeb24d36754fb104b2c 530 Gene3D G3DSA:3.40.50.300 305 529 3.1E-36 T 28-03-2018 CWM22_RS12125 b7e5f83b9c26deeb24d36754fb104b2c 530 Gene3D G3DSA:1.20.1560.10 1 304 7.9E-30 T 28-03-2018 CWM22_RS12125 b7e5f83b9c26deeb24d36754fb104b2c 530 Pfam PF00664 ABC transporter transmembrane region 14 281 1.9E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS12125 b7e5f83b9c26deeb24d36754fb104b2c 530 SUPERFAMILY SSF52540 322 527 1.26E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12125 b7e5f83b9c26deeb24d36754fb104b2c 530 SUPERFAMILY SSF90123 4 292 6.54E-34 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS12125 b7e5f83b9c26deeb24d36754fb104b2c 530 Pfam PF00005 ABC transporter 340 478 3.6E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS08290 b3e99ce471875840f221195cf104129c 423 SUPERFAMILY SSF103473 6 417 4.05E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWM22_RS08290 b3e99ce471875840f221195cf104129c 423 Gene3D G3DSA:1.20.1250.20 1 213 4.7E-10 T 28-03-2018 CWM22_RS08290 b3e99ce471875840f221195cf104129c 423 Gene3D G3DSA:1.20.1250.20 222 419 7.7E-11 T 28-03-2018 CWM22_RS08290 b3e99ce471875840f221195cf104129c 423 Pfam PF07690 Major Facilitator Superfamily 45 377 1.7E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWM22_RS03855 0ec284cbe1f42e4b08f29e77f386c16f 745 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 236 388 7.7E-11 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CWM22_RS03855 0ec284cbe1f42e4b08f29e77f386c16f 745 Pfam PF13567 Domain of unknown function (DUF4131) 28 176 1.9E-13 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 CWM22_RS03855 0ec284cbe1f42e4b08f29e77f386c16f 745 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 99 728 7.0E-74 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CWM22_RS03855 0ec284cbe1f42e4b08f29e77f386c16f 745 SUPERFAMILY SSF56281 486 732 8.26E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS03855 0ec284cbe1f42e4b08f29e77f386c16f 745 Pfam PF03772 Competence protein 215 459 6.3E-38 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CWM22_RS03855 0ec284cbe1f42e4b08f29e77f386c16f 745 Pfam PF00753 Metallo-beta-lactamase superfamily 493 697 9.6E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS03855 0ec284cbe1f42e4b08f29e77f386c16f 745 Gene3D G3DSA:3.60.15.10 478 724 4.1E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS03855 0ec284cbe1f42e4b08f29e77f386c16f 745 SMART SM00849 494 699 2.6E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS07710 9c0719827c22d4610fd9cfb6f7089cb0 381 PIRSF PIRSF038994 1 381 6.8E-118 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CWM22_RS07710 9c0719827c22d4610fd9cfb6f7089cb0 381 Gene3D G3DSA:3.20.20.140 67 350 3.4E-100 T 28-03-2018 CWM22_RS07710 9c0719827c22d4610fd9cfb6f7089cb0 381 SUPERFAMILY SSF51338 350 378 2.53E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWM22_RS07710 9c0719827c22d4610fd9cfb6f7089cb0 381 SUPERFAMILY SSF51338 2 52 2.53E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWM22_RS07710 9c0719827c22d4610fd9cfb6f7089cb0 381 Gene3D G3DSA:2.30.40.10 1 66 9.9E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWM22_RS07710 9c0719827c22d4610fd9cfb6f7089cb0 381 SUPERFAMILY SSF51556 53 350 4.56E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase CWM22_RS07710 9c0719827c22d4610fd9cfb6f7089cb0 381 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 3 375 4.1E-87 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CWM22_RS07710 9c0719827c22d4610fd9cfb6f7089cb0 381 Pfam PF01979 Amidohydrolase family 51 365 2.3E-17 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWM22_RS02330 62cc19ef629e058660cda817b9cbd007 502 Gene3D G3DSA:3.20.20.80 1 498 2.1E-163 T 28-03-2018 CWM22_RS02330 62cc19ef629e058660cda817b9cbd007 502 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 3 496 5.0E-97 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CWM22_RS02330 62cc19ef629e058660cda817b9cbd007 502 Pfam PF02446 4-alpha-glucanotransferase 10 475 7.5E-153 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CWM22_RS02330 62cc19ef629e058660cda817b9cbd007 502 SUPERFAMILY SSF51445 4 496 4.37E-164 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS04040 2a0792d83c8c536732f4062c08145e4f 140 Pfam PF07374 Protein of unknown function (DUF1492) 32 131 2.7E-49 T 28-03-2018 IPR010861 Protein of unknown function DUF1492 CWM22_RS04040 2a0792d83c8c536732f4062c08145e4f 140 Gene3D G3DSA:1.10.10.10 60 140 6.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS04040 2a0792d83c8c536732f4062c08145e4f 140 SUPERFAMILY SSF88659 82 136 2.01E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWM22_RS05875 77ba8c8d2853df0806931dc2304df781 595 Gene3D G3DSA:1.20.1560.10 19 332 1.2E-18 T 28-03-2018 CWM22_RS05875 77ba8c8d2853df0806931dc2304df781 595 SMART SM00382 380 566 2.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05875 77ba8c8d2853df0806931dc2304df781 595 SUPERFAMILY SSF90123 27 332 2.22E-23 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS05875 77ba8c8d2853df0806931dc2304df781 595 Pfam PF00005 ABC transporter 371 519 4.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS05875 77ba8c8d2853df0806931dc2304df781 595 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05875 77ba8c8d2853df0806931dc2304df781 595 SUPERFAMILY SSF52540 352 589 9.29E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05875 77ba8c8d2853df0806931dc2304df781 595 Gene3D G3DSA:3.40.50.300 349 595 4.7E-57 T 28-03-2018 CWM22_RS01160 80cca7b72c063080697d77b398db9c66 230 SUPERFAMILY SSF55729 24 197 9.25E-45 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS01160 80cca7b72c063080697d77b398db9c66 230 Pfam PF13302 Acetyltransferase (GNAT) domain 34 173 1.2E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS01160 80cca7b72c063080697d77b398db9c66 230 Gene3D G3DSA:3.40.630.30 18 205 3.8E-32 T 28-03-2018 CWM22_RS13285 75c45a4bccac382502fd0f769bccd846 374 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 362 41.33 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CWM22_RS13285 75c45a4bccac382502fd0f769bccd846 374 Gene3D G3DSA:2.30.30.280 215 282 4.9E-26 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CWM22_RS13285 75c45a4bccac382502fd0f769bccd846 374 Gene3D G3DSA:2.40.30.10 284 374 8.2E-29 T 28-03-2018 CWM22_RS13285 75c45a4bccac382502fd0f769bccd846 374 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 361 6.9E-137 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CWM22_RS13285 75c45a4bccac382502fd0f769bccd846 374 Pfam PF03054 tRNA methyl transferase 9 361 1.3E-146 T 28-03-2018 CWM22_RS13285 75c45a4bccac382502fd0f769bccd846 374 Gene3D G3DSA:3.40.50.620 1 214 3.1E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS13285 75c45a4bccac382502fd0f769bccd846 374 SUPERFAMILY SSF52402 6 245 8.82E-58 T 28-03-2018 CWM22_RS13425 6c55c4b9af87e33f801a8b028630825a 254 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 3 175 3.5E-51 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CWM22_RS13425 6c55c4b9af87e33f801a8b028630825a 254 Gene3D G3DSA:3.90.1530.10 1 95 6.8E-36 T 28-03-2018 CWM22_RS13425 6c55c4b9af87e33f801a8b028630825a 254 SUPERFAMILY SSF110849 5 97 1.92E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS13425 6c55c4b9af87e33f801a8b028630825a 254 Gene3D G3DSA:1.10.10.730 96 142 4.0E-19 T 28-03-2018 CWM22_RS13425 6c55c4b9af87e33f801a8b028630825a 254 Pfam PF02195 ParB-like nuclease domain 7 94 4.2E-25 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS13425 6c55c4b9af87e33f801a8b028630825a 254 SUPERFAMILY SSF109709 87 193 3.4E-34 T 28-03-2018 CWM22_RS13425 6c55c4b9af87e33f801a8b028630825a 254 SMART SM00470 5 95 4.3E-32 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWM22_RS01230 8bc1528fdcafdf4731823fde9e976192 389 Gene3D G3DSA:3.40.50.10490 217 381 7.1E-17 T 28-03-2018 CWM22_RS01230 8bc1528fdcafdf4731823fde9e976192 389 SUPERFAMILY SSF53697 17 378 2.53E-53 T 28-03-2018 CWM22_RS01230 8bc1528fdcafdf4731823fde9e976192 389 Gene3D G3DSA:3.40.50.10490 10 216 3.3E-24 T 28-03-2018 CWM22_RS01230 8bc1528fdcafdf4731823fde9e976192 389 Pfam PF01380 SIS domain 230 310 1.5E-7 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWM22_RS01230 8bc1528fdcafdf4731823fde9e976192 389 Pfam PF01380 SIS domain 57 188 1.6E-10 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWM22_RS02940 3802ac9026d96a7158f3f0b29c55771d 447 Pfam PF02601 Exonuclease VII, large subunit 122 436 3.3E-96 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CWM22_RS02940 3802ac9026d96a7158f3f0b29c55771d 447 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 2 439 28.264 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CWM22_RS02940 3802ac9026d96a7158f3f0b29c55771d 447 Pfam PF13742 OB-fold nucleic acid binding domain 5 97 1.6E-24 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CWM22_RS02940 3802ac9026d96a7158f3f0b29c55771d 447 Gene3D G3DSA:2.40.50.140 12 102 8.7E-9 T 28-03-2018 CWM22_RS02940 3802ac9026d96a7158f3f0b29c55771d 447 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 6 354 2.9E-129 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.1E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.1E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.1E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.1E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 Gene3D G3DSA:1.20.5.1150 16 52 2.9E-18 T 28-03-2018 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 Pfam PF01165 Ribosomal protein S21 5 56 3.4E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.32 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 6.0E-9 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04760 552b1c1d702450e8e4f8406bc667823e 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 7.7E-22 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS06560 be547a6df9f8a7edaf05a48fb84febb4 619 Pfam PF11083 Lantibiotic streptin immunity protein 516 607 4.0E-35 T 28-03-2018 IPR021112 Lantibiotic streptin immunity protein CWM22_RS06560 be547a6df9f8a7edaf05a48fb84febb4 619 Gene3D G3DSA:1.20.58.60 341 599 9.2E-4 T 28-03-2018 CWM22_RS06560 be547a6df9f8a7edaf05a48fb84febb4 619 Pfam PF03432 Relaxase/Mobilisation nuclease domain 11 249 1.9E-53 T 28-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 CWM22_RS01650 0e584e4f5282ff0df5e938f7e582aee4 559 Pfam PF02378 Phosphotransferase system, EIIC 28 347 5.1E-68 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWM22_RS01650 0e584e4f5282ff0df5e938f7e582aee4 559 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 420 554 1.1E-55 T 28-03-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWM22_RS01650 0e584e4f5282ff0df5e938f7e582aee4 559 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 460 527 2.4E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS01650 0e584e4f5282ff0df5e938f7e582aee4 559 SUPERFAMILY SSF52794 459 557 2.59E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS01650 0e584e4f5282ff0df5e938f7e582aee4 559 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 421 1.8E-77 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWM22_RS01650 0e584e4f5282ff0df5e938f7e582aee4 559 Gene3D G3DSA:3.40.50.2300 453 559 8.6E-20 T 28-03-2018 CWM22_RS01650 0e584e4f5282ff0df5e938f7e582aee4 559 TIGRFAM TIGR00394 lac_pts_IIC: PTS system, lactose-specific IIC component 11 421 4.9E-220 T 28-03-2018 IPR004801 Phosphotransferase system, lactose-specific IIC component GO:0008982|GO:0016021|GO:0022869 KEGG: 00052+2.7.1.207|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWM22_RS05910 7146ae9bd9d9d37bc006fe71466fee65 538 SMART SM00857 23 178 8.3E-28 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS05910 7146ae9bd9d9d37bc006fe71466fee65 538 Pfam PF07508 Recombinase 205 307 1.2E-13 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CWM22_RS05910 7146ae9bd9d9d37bc006fe71466fee65 538 Pfam PF00239 Resolvase, N terminal domain 25 176 1.1E-21 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS05910 7146ae9bd9d9d37bc006fe71466fee65 538 Gene3D G3DSA:3.40.50.1390 18 187 4.2E-40 T 28-03-2018 CWM22_RS05910 7146ae9bd9d9d37bc006fe71466fee65 538 Gene3D G3DSA:1.20.58.160 257 516 0.0036 T 28-03-2018 CWM22_RS05910 7146ae9bd9d9d37bc006fe71466fee65 538 SUPERFAMILY SSF53041 22 178 1.31E-27 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWM22_RS07650 1dd2e6e354ca7c37ed9be70ce58179d1 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 276 2.2E-30 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWM22_RS07650 1dd2e6e354ca7c37ed9be70ce58179d1 297 Gene3D G3DSA:1.10.3470.10 1 284 4.9E-33 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 SUPERFAMILY SSF53335 9 47 2.78E-138 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 SUPERFAMILY SSF53335 89 512 2.78E-138 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 Gene3D G3DSA:3.40.50.150 194 474 1.8E-72 T 28-03-2018 CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 333 357 2.5E-20 T 28-03-2018 CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 196 212 2.5E-20 T 28-03-2018 CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 297 309 2.5E-20 T 28-03-2018 CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 224 238 2.5E-20 T 28-03-2018 CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 Pfam PF12161 HsdM N-terminal domain 10 162 7.5E-25 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 Pfam PF02384 N-6 DNA Methylase 172 479 2.6E-108 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CWM22_RS04655 3ebd651f6ce82d6ef08d974e1d7ab021 531 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 10 493 4.7E-114 T 28-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 CWM22_RS07055 e56c758c588a6c619df05bf1102db9f2 282 SUPERFAMILY SSF47413 4 64 4.22E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS07055 e56c758c588a6c619df05bf1102db9f2 282 Gene3D G3DSA:1.10.260.40 5 278 7.3E-10 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 5 41 3.2E-7 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 952 1031 7.0E-6 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 811 883 6.1E-6 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 661 741 7.3E-9 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 331 411 2.3E-10 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 1100 1182 6.8E-6 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 746 810 0.11 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 1254 1331 1.8E-10 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 1032 1098 0.055 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 884 951 0.04 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 SMART SM01208 1249 1327 2.5E-4 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 SMART SM01208 805 884 0.29 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 SMART SM01208 659 736 4.6E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 SMART SM01208 953 1032 0.4 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 SMART SM01208 434 510 2.0E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 SMART SM01208 1101 1180 0.56 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 SMART SM01208 229 305 0.012 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 SMART SM01208 522 594 1.5E-8 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 SMART SM01208 331 407 7.6E-8 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Pfam PF04650 YSIRK type signal peptide 7 29 2.6E-5 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Pfam PF07501 G5 domain 668 735 1.5E-5 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Pfam PF07501 G5 domain 441 508 1.2E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Pfam PF07501 G5 domain 528 592 9.5E-8 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Pfam PF07501 G5 domain 337 405 1.3E-7 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Pfam PF07501 G5 domain 1253 1326 1.5E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Pfam PF07580 M26 IgA1-specific Metallo-endopeptidase C-terminal region 1949 2699 9.0E-141 T 28-03-2018 IPR011505 Peptidase M26, C-terminal domain GO:0004222|GO:0005576|GO:0005618|GO:0008270 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Pfam PF05342 M26 IgA1-specific Metallo-endopeptidase N-terminal region 1406 1648 2.0E-45 T 28-03-2018 IPR008006 Peptidase M26, N-terminal domain GO:0004222|GO:0008270|GO:0016021 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 527 593 5.3E-8 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 1183 1253 0.59 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 436 510 1.5E-10 T 28-03-2018 CWM22_RS03455 45e0c1886cda700e40ce47e27a38d2b3 2701 Gene3D G3DSA:2.20.230.10 233 305 2.2E-4 T 28-03-2018 CWM22_RS10095 e843526e3c2013d4c6a733b9ce03d47e 245 SUPERFAMILY SSF102198 14 244 1.83E-57 T 28-03-2018 CWM22_RS10095 e843526e3c2013d4c6a733b9ce03d47e 245 Pfam PF04199 Putative cyclase 17 181 2.0E-31 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CWM22_RS10095 e843526e3c2013d4c6a733b9ce03d47e 245 Gene3D G3DSA:3.50.30.50 12 245 4.3E-51 T 28-03-2018 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 37 172 1.6E-24 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 Gene3D G3DSA:1.10.340.30 25 119 1.3E-28 T 28-03-2018 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 Pfam PF00633 Helix-hairpin-helix motif 101 129 4.7E-10 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 ProSitePatterns PS01155 Endonuclease III family signature. 104 133 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 Hamap MF_00942 Endonuclease III [nth]. 2 203 34.468 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 Gene3D G3DSA:1.10.1670.10 120 202 1.3E-28 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 SMART SM00478 40 188 4.3E-62 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 PIRSF PIRSF001435 1 202 1.3E-47 T 28-03-2018 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 TIGRFAM TIGR01083 nth: endonuclease III 5 197 6.1E-70 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CWM22_RS07060 15355f8f84602b40de506ca6daba8c3a 207 SUPERFAMILY SSF48150 4 198 6.44E-68 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CWM22_RS12515 04ff98276204786e279e34e74eeaa064 161 Gene3D G3DSA:3.40.930.10 2 149 9.8E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS12515 04ff98276204786e279e34e74eeaa064 161 SUPERFAMILY SSF55804 6 147 1.92E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWM22_RS12515 04ff98276204786e279e34e74eeaa064 161 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 147 2.5E-31 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CWM22_RS00580 ac0ca9a7d110ad0f6314dbf99e099e4f 164 Gene3D G3DSA:3.30.160.20 9 71 2.6E-29 T 28-03-2018 CWM22_RS00580 ac0ca9a7d110ad0f6314dbf99e099e4f 164 SUPERFAMILY SSF54211 79 157 8.34E-25 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS00580 ac0ca9a7d110ad0f6314dbf99e099e4f 164 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CWM22_RS00580 ac0ca9a7d110ad0f6314dbf99e099e4f 164 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 74 2.6E-31 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CWM22_RS00580 ac0ca9a7d110ad0f6314dbf99e099e4f 164 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 161 1.3E-67 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWM22_RS00580 ac0ca9a7d110ad0f6314dbf99e099e4f 164 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 35.772 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWM22_RS00580 ac0ca9a7d110ad0f6314dbf99e099e4f 164 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 156 1.9E-28 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CWM22_RS00580 ac0ca9a7d110ad0f6314dbf99e099e4f 164 SUPERFAMILY SSF54768 9 75 1.57E-24 T 28-03-2018 CWM22_RS00580 ac0ca9a7d110ad0f6314dbf99e099e4f 164 Gene3D G3DSA:3.30.230.10 75 164 1.2E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS03930 7aa4fad7210baf10b199815f8a0f5288 63 SMART SM00530 4 60 1.2E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS03930 7aa4fad7210baf10b199815f8a0f5288 63 SUPERFAMILY SSF47413 3 60 1.1E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS03930 7aa4fad7210baf10b199815f8a0f5288 63 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 4 60 5.7E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS03930 7aa4fad7210baf10b199815f8a0f5288 63 Gene3D G3DSA:1.10.260.40 2 63 3.4E-11 T 28-03-2018 CWM22_RS12335 35cedb37c57cd34efb5e53af314d51a3 177 SMART SM00855 2 161 1.5E-4 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS12335 35cedb37c57cd34efb5e53af314d51a3 177 SUPERFAMILY SSF53254 1 162 5.35E-22 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS12335 35cedb37c57cd34efb5e53af314d51a3 177 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 161 2.4E-16 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS12335 35cedb37c57cd34efb5e53af314d51a3 177 Gene3D G3DSA:3.40.50.1240 1 164 1.1E-20 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS03555 ecf626b1f213c52226c433ce947328de 238 Gene3D G3DSA:1.10.3290.10 3 236 1.4E-47 T 28-03-2018 IPR003812 Fido domain CWM22_RS03555 ecf626b1f213c52226c433ce947328de 238 Pfam PF02661 Fic/DOC family 86 180 4.6E-18 T 28-03-2018 IPR003812 Fido domain CWM22_RS03555 ecf626b1f213c52226c433ce947328de 238 SUPERFAMILY SSF140931 63 232 6.02E-34 T 28-03-2018 IPR003812 Fido domain CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 Gene3D G3DSA:3.40.50.300 367 569 4.5E-23 T 28-03-2018 CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 245 832 6.6E-99 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 Gene3D G3DSA:3.40.50.300 609 829 3.6E-8 T 28-03-2018 CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 838 1104 5.3E-35 T 28-03-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 SMART SM00487 383 581 1.7E-12 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 SUPERFAMILY SSF52540 377 558 6.45E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 Pfam PF04851 Type III restriction enzyme, res subunit 387 554 8.8E-31 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 SUPERFAMILY SSF52540 714 806 6.2E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 SUPERFAMILY SSF52540 520 553 6.2E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 SUPERFAMILY SSF52540 655 682 6.2E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04630 5df2a4a34492925b0000a0cb6acd76a7 1120 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 152 332 1.1E-20 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 CWM22_RS09525 226960218b19512c8d639e3aa2cc3cf6 579 SMART SM00382 366 558 3.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS09525 226960218b19512c8d639e3aa2cc3cf6 579 Gene3D G3DSA:3.40.50.300 328 578 4.2E-69 T 28-03-2018 CWM22_RS09525 226960218b19512c8d639e3aa2cc3cf6 579 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS09525 226960218b19512c8d639e3aa2cc3cf6 579 Pfam PF00664 ABC transporter transmembrane region 19 296 8.2E-35 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS09525 226960218b19512c8d639e3aa2cc3cf6 579 Gene3D G3DSA:1.20.1560.10 1 327 2.2E-53 T 28-03-2018 CWM22_RS09525 226960218b19512c8d639e3aa2cc3cf6 579 Pfam PF00005 ABC transporter 357 506 4.5E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS09525 226960218b19512c8d639e3aa2cc3cf6 579 SUPERFAMILY SSF90123 7 328 3.53E-56 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS09525 226960218b19512c8d639e3aa2cc3cf6 579 SUPERFAMILY SSF52540 332 576 8.21E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01865 85512cbf90534e11eb4c22096bc70e88 231 SUPERFAMILY SSF53254 4 223 1.56E-49 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS01865 85512cbf90534e11eb4c22096bc70e88 231 Gene3D G3DSA:3.40.50.1240 2 229 7.9E-43 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWM22_RS01865 85512cbf90534e11eb4c22096bc70e88 231 SMART SM00855 5 180 4.6E-19 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS01865 85512cbf90534e11eb4c22096bc70e88 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 216 1.3E-33 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWM22_RS01865 85512cbf90534e11eb4c22096bc70e88 231 PIRSF PIRSF000709 1 108 4.0E-5 T 28-03-2018 CWM22_RS01865 85512cbf90534e11eb4c22096bc70e88 231 PIRSF PIRSF000709 152 182 240.0 T 28-03-2018 CWM22_RS07440 380bc08bc52a82b259e480a2783573de 316 SUPERFAMILY SSF54593 1 274 9.07E-35 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS07440 380bc08bc52a82b259e480a2783573de 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 126 2.4E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWM22_RS07440 380bc08bc52a82b259e480a2783573de 316 Gene3D G3DSA:3.10.180.10 146 316 8.8E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS07440 380bc08bc52a82b259e480a2783573de 316 Gene3D G3DSA:3.10.180.10 1 141 7.3E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS07575 694b904c9c979015f88b8e243205cf96 233 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 3 194 6.1E-33 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CWM22_RS07575 694b904c9c979015f88b8e243205cf96 233 Gene3D G3DSA:3.40.50.10300 1 232 3.8E-58 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CWM22_RS07575 694b904c9c979015f88b8e243205cf96 233 TIGRFAM TIGR02114 coaB_strep: phosphopantothenate--cysteine ligase 3 228 3.6E-102 T 28-03-2018 IPR011848 Phosphopantothenate--cysteine ligase CWM22_RS07575 694b904c9c979015f88b8e243205cf96 233 SUPERFAMILY SSF102645 2 228 1.7E-49 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CWM22_RS12385 2b2b8e5aac54582201e2a84407073875 119 Pfam PF04304 Protein of unknown function (DUF454) 3 117 3.6E-38 T 28-03-2018 IPR007401 Protein of unknown function DUF454 CWM22_RS12385 2b2b8e5aac54582201e2a84407073875 119 PIRSF PIRSF016789 2 119 5.1E-39 T 28-03-2018 IPR007401 Protein of unknown function DUF454 CWM22_RS08180 1cc2136fe5fea22576920698fe3e3db2 168 Pfam PF00430 ATP synthase B/B' CF(0) 16 145 2.8E-26 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CWM22_RS08180 1cc2136fe5fea22576920698fe3e3db2 168 SUPERFAMILY SSF81573 72 130 2.48E-6 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CWM22_RS08180 1cc2136fe5fea22576920698fe3e3db2 168 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 20 165 1.4E-33 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CWM22_RS08180 1cc2136fe5fea22576920698fe3e3db2 168 Hamap MF_01398 ATP synthase subunit b [atpF]. 7 147 12.653 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CWM22_RS09475 90db7777ceab5e8e789d813af0d07286 322 Gene3D G3DSA:3.40.50.1820 3 315 9.5E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS09475 90db7777ceab5e8e789d813af0d07286 322 Pfam PF05448 Acetyl xylan esterase (AXE1) 4 315 1.3E-112 T 28-03-2018 IPR008391 Acetyl xylan esterase CWM22_RS09475 90db7777ceab5e8e789d813af0d07286 322 SUPERFAMILY SSF53474 4 313 5.45E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS01745 258a9931a7069287ace0a9c27fbc1f77 872 Pfam PF00746 LPXTG cell wall anchor motif 837 870 5.3E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS01745 258a9931a7069287ace0a9c27fbc1f77 872 Gene3D G3DSA:1.10.287.620 176 336 6.3E-11 T 28-03-2018 CWM22_RS01745 258a9931a7069287ace0a9c27fbc1f77 872 Gene3D G3DSA:1.10.287.620 596 763 2.8E-12 T 28-03-2018 CWM22_RS01745 258a9931a7069287ace0a9c27fbc1f77 872 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 839 870 4.7E-7 T 28-03-2018 CWM22_RS01745 258a9931a7069287ace0a9c27fbc1f77 872 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 314 631 3.2E-63 T 28-03-2018 IPR027607 SEC10/PgrA surface exclusion domain CWM22_RS00590 bf5bcf4591562426b15c5f28cbeb958a 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.577 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CWM22_RS00590 bf5bcf4591562426b15c5f28cbeb958a 146 Gene3D G3DSA:3.100.10.10 42 146 4.7E-32 T 28-03-2018 CWM22_RS00590 bf5bcf4591562426b15c5f28cbeb958a 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 1.8E-55 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00590 bf5bcf4591562426b15c5f28cbeb958a 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 1.0E-38 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CWM22_RS00590 bf5bcf4591562426b15c5f28cbeb958a 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00590 bf5bcf4591562426b15c5f28cbeb958a 146 SUPERFAMILY SSF52080 4 144 1.57E-49 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CWM22_RS08665 3efd347cf340b74ccc1c8ed5110c2693 90 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 7 76 1.9E-26 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CWM22_RS08665 3efd347cf340b74ccc1c8ed5110c2693 90 Hamap MF_01126 UPF0298 protein . 3 80 20.495 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CWM22_RS08665 3efd347cf340b74ccc1c8ed5110c2693 90 PIRSF PIRSF031653 1 88 3.1E-30 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 SUPERFAMILY SSF82679 7 118 2.49E-35 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 Gene3D G3DSA:2.30.30.30 122 179 5.6E-14 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 SMART SM00739 127 154 9.8E-7 T 28-03-2018 IPR005824 KOW CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 Pfam PF02357 Transcription termination factor nusG 7 114 8.8E-27 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 Gene3D G3DSA:3.30.70.940 6 121 5.3E-38 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 179 22.037 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 SMART SM00738 6 117 2.5E-49 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 1.4E-6 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 PRINTS PR00338 Transcription termination factor NUSG signature 155 171 1.4E-6 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 SUPERFAMILY SSF50104 125 178 9.89E-13 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 177 5.7E-48 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWM22_RS11955 f4258c777a4e41ed6ee59de99cd3e362 179 Pfam PF00467 KOW motif 130 159 4.7E-7 T 28-03-2018 IPR005824 KOW CWM22_RS12135 8c94c2f9fe4d0c8d69575c2db11c528a 288 Pfam PF01381 Helix-turn-helix 8 61 1.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12135 8c94c2f9fe4d0c8d69575c2db11c528a 288 SMART SM00530 7 61 4.2E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12135 8c94c2f9fe4d0c8d69575c2db11c528a 288 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 63 286 4.3E-43 T 28-03-2018 IPR010057 Transcription activator MutR, C-terminal CWM22_RS12135 8c94c2f9fe4d0c8d69575c2db11c528a 288 Gene3D G3DSA:1.10.260.40 1 108 4.1E-12 T 28-03-2018 CWM22_RS12135 8c94c2f9fe4d0c8d69575c2db11c528a 288 SUPERFAMILY SSF47413 4 63 3.85E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS00330 31b22450c780345f5a56a720b8530d46 357 SUPERFAMILY SSF56059 101 296 1.04E-54 T 28-03-2018 CWM22_RS00330 31b22450c780345f5a56a720b8530d46 357 SUPERFAMILY SSF52440 4 88 2.59E-25 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWM22_RS00330 31b22450c780345f5a56a720b8530d46 357 Gene3D G3DSA:3.30.1490.20 118 178 8.1E-10 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWM22_RS00330 31b22450c780345f5a56a720b8530d46 357 Gene3D G3DSA:3.30.470.20 179 356 1.1E-38 T 28-03-2018 CWM22_RS00330 31b22450c780345f5a56a720b8530d46 357 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 6 351 40.985 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CWM22_RS00330 31b22450c780345f5a56a720b8530d46 357 SUPERFAMILY SSF51246 300 355 4.94E-16 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWM22_RS00330 31b22450c780345f5a56a720b8530d46 357 Gene3D G3DSA:3.40.50.20 4 89 5.6E-26 T 28-03-2018 CWM22_RS00330 31b22450c780345f5a56a720b8530d46 357 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 6 355 4.3E-112 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CWM22_RS00330 31b22450c780345f5a56a720b8530d46 357 Pfam PF02222 ATP-grasp domain 111 276 3.1E-46 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CWM22_RS03150 d0c5a22f717fddd04f6527c8b951ec53 144 Pfam PF10263 SprT-like family 7 94 1.0E-9 T 28-03-2018 IPR006640 SprT-like CWM22_RS03150 d0c5a22f717fddd04f6527c8b951ec53 144 SMART SM00731 1 143 3.5E-58 T 28-03-2018 IPR006640 SprT-like CWM22_RS03150 d0c5a22f717fddd04f6527c8b951ec53 144 Pfam PF17283 SprT-like zinc ribbon domain 111 143 4.8E-8 T 28-03-2018 IPR035240 SprT-like, zinc ribbon domain CWM22_RS03150 d0c5a22f717fddd04f6527c8b951ec53 144 Hamap MF_00745 Protein SprT-like. 1 143 39.602 T 28-03-2018 IPR023524 Uncharacterised protein family SprT-like CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 PIRSF PIRSF000111 4 876 0.0 T 28-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 Pfam PF00171 Aldehyde dehydrogenase family 17 419 1.8E-25 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 647 675 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 SUPERFAMILY SSF53720 337 469 2.88E-81 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 SUPERFAMILY SSF53720 18 308 2.88E-81 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 Pfam PF00465 Iron-containing alcohol dehydrogenase 473 860 2.2E-117 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 Gene3D G3DSA:3.40.309.10 241 421 2.9E-27 T 28-03-2018 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 733 753 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 Gene3D G3DSA:3.40.605.10 7 240 5.5E-28 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 Gene3D G3DSA:3.40.50.1970 446 658 1.1E-51 T 28-03-2018 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 SUPERFAMILY SSF56796 464 876 4.58E-118 T 28-03-2018 CWM22_RS01765 2e5069475bae7fa6d64001ddcaa6c1c6 883 Gene3D G3DSA:1.20.1090.10 659 878 4.5E-58 T 28-03-2018 CWM22_RS05105 4a6d9970e473507bd0d879a4739adf74 220 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 211 3.2E-93 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWM22_RS05105 4a6d9970e473507bd0d879a4739adf74 220 SUPERFAMILY SSF51569 1 213 5.34E-87 T 28-03-2018 CWM22_RS05105 4a6d9970e473507bd0d879a4739adf74 220 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 215 38.585 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CWM22_RS05105 4a6d9970e473507bd0d879a4739adf74 220 Pfam PF01791 DeoC/LacD family aldolase 5 210 1.0E-18 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWM22_RS05105 4a6d9970e473507bd0d879a4739adf74 220 PIRSF PIRSF001357 1 219 3.4E-79 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWM22_RS05105 4a6d9970e473507bd0d879a4739adf74 220 Gene3D G3DSA:3.20.20.70 1 216 5.8E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS05105 4a6d9970e473507bd0d879a4739adf74 220 SMART SM01133 2 213 5.4E-108 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWM22_RS05350 54ee376db72a7b457525b04b05243083 223 Pfam PF04607 Region found in RelA / SpoT proteins 44 163 8.6E-38 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWM22_RS05350 54ee376db72a7b457525b04b05243083 223 SUPERFAMILY SSF81301 2 198 3.27E-58 T 28-03-2018 CWM22_RS05350 54ee376db72a7b457525b04b05243083 223 Gene3D G3DSA:3.30.460.10 2 146 9.6E-37 T 28-03-2018 CWM22_RS05350 54ee376db72a7b457525b04b05243083 223 SMART SM00954 44 165 4.9E-44 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWM22_RS05350 54ee376db72a7b457525b04b05243083 223 Gene3D G3DSA:1.10.287.860 148 196 9.6E-20 T 28-03-2018 CWM22_RS00560 a8a3f7fb743956284eabb2b6e72cf909 61 Pfam PF00253 Ribosomal protein S14p/S29e 12 60 1.2E-22 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00560 a8a3f7fb743956284eabb2b6e72cf909 61 SUPERFAMILY SSF57716 4 61 2.0E-20 T 28-03-2018 CWM22_RS00560 a8a3f7fb743956284eabb2b6e72cf909 61 Gene3D G3DSA:4.10.830.10 1 61 3.8E-20 T 28-03-2018 CWM22_RS00560 a8a3f7fb743956284eabb2b6e72cf909 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.157 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z CWM22_RS00560 a8a3f7fb743956284eabb2b6e72cf909 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS11225 078b11a07ef45ef305321bc420b76611 439 Pfam PF04055 Radical SAM superfamily 116 264 7.7E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWM22_RS11225 078b11a07ef45ef305321bc420b76611 439 Gene3D G3DSA:3.20.20.70 92 403 7.4E-34 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS11225 078b11a07ef45ef305321bc420b76611 439 SMART SM00729 107 305 2.2E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWM22_RS11225 078b11a07ef45ef305321bc420b76611 439 TIGRFAM TIGR04080 rSAM_pep_cyc: KxxxW cyclic peptide radical SAM maturase 1 439 3.2E-265 T 28-03-2018 IPR024017 Petide cyclisation enzyme, radical SAM CWM22_RS11225 078b11a07ef45ef305321bc420b76611 439 SUPERFAMILY SSF102114 105 419 1.09E-48 T 28-03-2018 CWM22_RS11225 078b11a07ef45ef305321bc420b76611 439 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 347 428 1.6E-11 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain CWM22_RS11225 078b11a07ef45ef305321bc420b76611 439 Pfam PF13394 4Fe-4S single cluster domain 117 192 5.6E-5 T 28-03-2018 CWM22_RS07400 d325b3a373d9f1ec95867f025fc5af1d 128 Gene3D G3DSA:3.40.1440.10 9 113 8.4E-7 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS11970 e8304ad0f7b959300641c3d78e525ad1 727 SUPERFAMILY SSF56601 244 266 1.23E-94 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS11970 e8304ad0f7b959300641c3d78e525ad1 727 SUPERFAMILY SSF56601 299 653 1.23E-94 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS11970 e8304ad0f7b959300641c3d78e525ad1 727 Pfam PF00912 Transglycosylase 97 262 2.8E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWM22_RS11970 e8304ad0f7b959300641c3d78e525ad1 727 Gene3D G3DSA:1.10.3810.10 84 279 2.3E-71 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWM22_RS11970 e8304ad0f7b959300641c3d78e525ad1 727 SUPERFAMILY SSF53955 82 283 1.21E-67 T 28-03-2018 IPR023346 Lysozyme-like domain CWM22_RS11970 e8304ad0f7b959300641c3d78e525ad1 727 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 103 643 7.5E-156 T 28-03-2018 CWM22_RS11970 e8304ad0f7b959300641c3d78e525ad1 727 Gene3D G3DSA:3.40.710.10 285 701 5.2E-82 T 28-03-2018 CWM22_RS11970 e8304ad0f7b959300641c3d78e525ad1 727 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 606 1.6E-32 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWM22_RS05150 49f3e272a125dff75fd8f98ab4326c49 222 Pfam PF13384 Homeodomain-like domain 25 67 2.3E-6 T 28-03-2018 CWM22_RS05150 49f3e272a125dff75fd8f98ab4326c49 222 Gene3D G3DSA:1.10.10.10 1 195 9.5E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05150 49f3e272a125dff75fd8f98ab4326c49 222 SUPERFAMILY SSF46689 22 133 1.61E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS07885 03cd3139ba6cf5fe69958d4c96186535 283 Gene3D G3DSA:3.90.25.10 199 267 1.2E-19 T 28-03-2018 CWM22_RS07885 03cd3139ba6cf5fe69958d4c96186535 283 Gene3D G3DSA:3.40.50.720 1 198 5.6E-34 T 28-03-2018 CWM22_RS07885 03cd3139ba6cf5fe69958d4c96186535 283 SUPERFAMILY SSF51735 2 280 1.26E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS07885 03cd3139ba6cf5fe69958d4c96186535 283 Pfam PF04321 RmlD substrate binding domain 2 280 3.9E-105 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CWM22_RS07885 03cd3139ba6cf5fe69958d4c96186535 283 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 279 3.0E-79 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 SUPERFAMILY SSF52096 35 284 2.34E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 256 265 1.5E-35 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 168 186 1.5E-35 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 205 222 1.5E-35 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 148 1.5E-35 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 234 245 1.5E-35 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 21 284 1.3E-105 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 Pfam PF01039 Carboxyl transferase domain 65 246 7.8E-18 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 Gene3D G3DSA:3.90.226.10 22 286 6.3E-65 T 28-03-2018 CWM22_RS10905 549398e806da8a5fd6a85675162695ce 288 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 286 38.413 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 332 58.368 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 8.0E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 8.0E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 8.0E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 8.0E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 156 177 8.0E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 266 275 8.0E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 Gene3D G3DSA:3.30.420.40 147 294 7.2E-16 T 28-03-2018 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 Pfam PF00814 Glycoprotease family 26 307 3.6E-101 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 SUPERFAMILY SSF53067 5 311 1.81E-41 T 28-03-2018 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 314 8.3E-130 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 Gene3D G3DSA:3.30.420.40 4 146 3.1E-40 T 28-03-2018 CWM22_RS01110 842915b5e5842be4309e31ecae85b119 335 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 307 2.6E-105 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWM22_RS08700 b855654a0ae3083cf57b10f59ebf2bcf 413 Gene3D G3DSA:3.40.190.10 156 354 6.0E-47 T 28-03-2018 CWM22_RS08700 b855654a0ae3083cf57b10f59ebf2bcf 413 Pfam PF13416 Bacterial extracellular solute-binding protein 50 355 2.0E-42 T 28-03-2018 CWM22_RS08700 b855654a0ae3083cf57b10f59ebf2bcf 413 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 137 154 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 CWM22_RS08700 b855654a0ae3083cf57b10f59ebf2bcf 413 SUPERFAMILY SSF53850 20 404 2.17E-73 T 28-03-2018 CWM22_RS08700 b855654a0ae3083cf57b10f59ebf2bcf 413 Gene3D G3DSA:3.40.190.10 25 155 3.7E-21 T 28-03-2018 CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 SMART SM00740 689 749 2.8E-10 T 28-03-2018 IPR005543 PASTA domain CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 SUPERFAMILY SSF54184 632 691 7.98E-15 T 28-03-2018 CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 SUPERFAMILY SSF56601 265 611 2.0E-68 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 Pfam PF03793 PASTA domain 694 748 9.2E-6 T 28-03-2018 IPR005543 PASTA domain CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 Gene3D G3DSA:3.90.1310.10 39 260 3.2E-31 T 28-03-2018 CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 Gene3D G3DSA:3.40.710.10 261 611 1.6E-54 T 28-03-2018 CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 Pfam PF03717 Penicillin-binding Protein dimerisation domain 73 246 1.0E-28 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 SUPERFAMILY SSF54184 694 748 2.35E-11 T 28-03-2018 CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 Pfam PF00905 Penicillin binding protein transpeptidase domain 292 592 3.4E-68 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWM22_RS10600 5766e0ba4c7d407fa5078f9a1fa4963f 749 SUPERFAMILY SSF56519 69 263 2.35E-47 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWM22_RS09600 615e129383871c13f2fde521b64e31f5 783 Gene3D G3DSA:1.20.5.1230 3 425 2.0E-7 T 28-03-2018 CWM22_RS09600 615e129383871c13f2fde521b64e31f5 783 Gene3D G3DSA:1.20.5.1230 426 655 7.6E-12 T 28-03-2018 CWM22_RS05465 fa2bd5aef347b9843a3fd9fe5f72c5d4 156 SUPERFAMILY SSF55729 8 138 4.01E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS05465 fa2bd5aef347b9843a3fd9fe5f72c5d4 156 Gene3D G3DSA:3.40.630.30 5 147 4.0E-24 T 28-03-2018 CWM22_RS05465 fa2bd5aef347b9843a3fd9fe5f72c5d4 156 Pfam PF00583 Acetyltransferase (GNAT) family 20 126 8.3E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS01545 58c53aa9d569ab1cf434309ca978efbb 177 Gene3D G3DSA:1.10.10.60 2 47 2.4E-15 T 28-03-2018 CWM22_RS01545 58c53aa9d569ab1cf434309ca978efbb 177 Gene3D G3DSA:1.10.10.60 48 156 3.1E-6 T 28-03-2018 CWM22_RS01545 58c53aa9d569ab1cf434309ca978efbb 177 SUPERFAMILY SSF46689 5 70 2.5E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS01545 58c53aa9d569ab1cf434309ca978efbb 177 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS01545 58c53aa9d569ab1cf434309ca978efbb 177 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS01545 58c53aa9d569ab1cf434309ca978efbb 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 5.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS02310 244f41c7367a82683e7cc65401e46287 408 Gene3D G3DSA:3.40.630.30 166 375 6.6E-26 T 28-03-2018 CWM22_RS02310 244f41c7367a82683e7cc65401e46287 408 SUPERFAMILY SSF55729 171 243 1.27E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS02310 244f41c7367a82683e7cc65401e46287 408 SUPERFAMILY SSF55729 301 395 1.27E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS02310 244f41c7367a82683e7cc65401e46287 408 Gene3D G3DSA:3.40.630.30 1 165 8.0E-38 T 28-03-2018 CWM22_RS02310 244f41c7367a82683e7cc65401e46287 408 SUPERFAMILY SSF55729 1 172 1.43E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS02310 244f41c7367a82683e7cc65401e46287 408 Pfam PF02388 FemAB family 9 397 1.4E-107 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CWM22_RS11140 00778355cbc2ddc812e3c0f36d35aa56 79 Pfam PF04193 PQ loop repeat 2 54 2.3E-11 T 28-03-2018 IPR006603 PQ-loop repeat CWM22_RS12980 c13cf7e2bb81c347e88a47deaf71fa34 97 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 66 1.5E-18 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ CWM22_RS12980 c13cf7e2bb81c347e88a47deaf71fa34 97 Pfam PF04221 RelB antitoxin 1 50 7.3E-13 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ CWM22_RS03440 28340535a0ee1071b903813c68a2de22 151 SUPERFAMILY SSF159888 7 134 5.1E-9 T 28-03-2018 CWM22_RS03440 28340535a0ee1071b903813c68a2de22 151 Pfam PF08818 Domain of unknown function (DU1801) 19 135 1.5E-12 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CWM22_RS05690 046033f6e35e5dd49d36756a91fc6f77 124 Pfam PF14198 Transposon-encoded protein TnpV 12 122 1.1E-43 T 28-03-2018 IPR026989 Transposon-encoded protein TnpV CWM22_RS06980 9eb40f929dd77fe69687dafd5902f48b 283 Gene3D G3DSA:3.30.1180.10 155 280 1.8E-38 T 28-03-2018 CWM22_RS06980 9eb40f929dd77fe69687dafd5902f48b 283 SUPERFAMILY SSF82549 1 278 1.57E-86 T 28-03-2018 CWM22_RS06980 9eb40f929dd77fe69687dafd5902f48b 283 Gene3D G3DSA:2.20.28.50 29 53 3.9E-17 T 28-03-2018 CWM22_RS06980 9eb40f929dd77fe69687dafd5902f48b 283 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 1.9E-92 T 28-03-2018 IPR003797 DegV CWM22_RS06980 9eb40f929dd77fe69687dafd5902f48b 283 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 279 4.2E-90 T 28-03-2018 IPR003797 DegV CWM22_RS06980 9eb40f929dd77fe69687dafd5902f48b 283 Gene3D G3DSA:3.40.50.10440 54 150 3.6E-26 T 28-03-2018 CWM22_RS04685 3208c29299bebb1ee49020ced2fa360b 755 Gene3D G3DSA:3.40.50.2000 418 737 1.4E-110 T 28-03-2018 CWM22_RS04685 3208c29299bebb1ee49020ced2fa360b 755 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 595 607 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWM22_RS04685 3208c29299bebb1ee49020ced2fa360b 755 PIRSF PIRSF000460 2 755 7.2E-191 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWM22_RS04685 3208c29299bebb1ee49020ced2fa360b 755 SUPERFAMILY SSF53756 4 753 7.46E-251 T 28-03-2018 CWM22_RS04685 3208c29299bebb1ee49020ced2fa360b 755 Gene3D G3DSA:3.40.50.2000 2 417 3.0E-132 T 28-03-2018 CWM22_RS04685 3208c29299bebb1ee49020ced2fa360b 755 Pfam PF00343 Carbohydrate phosphorylase 79 752 2.3E-252 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWM22_RS04685 3208c29299bebb1ee49020ced2fa360b 755 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 6 752 6.9E-273 T 28-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CWM22_RS12765 e6389f86b981fb7bd3dc386cff0af340 248 PIRSF PIRSF015601 1 246 6.2E-49 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS12765 e6389f86b981fb7bd3dc386cff0af340 248 SUPERFAMILY SSF75217 69 246 9.16E-51 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWM22_RS12765 e6389f86b981fb7bd3dc386cff0af340 248 Gene3D G3DSA:3.40.1280.10 1 248 8.4E-66 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWM22_RS12765 e6389f86b981fb7bd3dc386cff0af340 248 SUPERFAMILY SSF88697 2 62 1.07E-11 T 28-03-2018 IPR015947 PUA-like domain CWM22_RS12765 e6389f86b981fb7bd3dc386cff0af340 248 Pfam PF04452 RNA methyltransferase 18 242 2.2E-66 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS12765 e6389f86b981fb7bd3dc386cff0af340 248 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 19 245 7.9E-48 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWM22_RS02265 677f46d1a460c0761867c476e78aca34 117 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 6.6E-36 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CWM22_RS02265 677f46d1a460c0761867c476e78aca34 117 Gene3D G3DSA:3.30.460.10 1 114 1.3E-34 T 28-03-2018 CWM22_RS02265 677f46d1a460c0761867c476e78aca34 117 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 2.4E-27 T 28-03-2018 CWM22_RS02265 677f46d1a460c0761867c476e78aca34 117 SUPERFAMILY SSF81301 1 114 1.8E-39 T 28-03-2018 CWM22_RS02265 677f46d1a460c0761867c476e78aca34 117 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 105 25.935 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CWM22_RS03090 5840e7ad3c7b4b32a9be61103b37c1ed 226 SUPERFAMILY SSF54631 75 221 3.93E-8 T 28-03-2018 CWM22_RS03090 5840e7ad3c7b4b32a9be61103b37c1ed 226 Gene3D G3DSA:3.10.580.10 75 223 1.3E-9 T 28-03-2018 CWM22_RS03970 ac993f93986ebfa69b95f7e529f1a252 156 Pfam PF05037 Protein of unknown function (DUF669) 5 134 1.5E-20 T 28-03-2018 IPR007731 Protein of unknown function DUF669 CWM22_RS08705 c8d3677df8ae81e8163db9312be7d1f5 484 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 25 38 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CWM22_RS08705 c8d3677df8ae81e8163db9312be7d1f5 484 Gene3D G3DSA:2.115.10.20 30 347 2.4E-97 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWM22_RS08705 c8d3677df8ae81e8163db9312be7d1f5 484 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 336 480 9.4E-14 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CWM22_RS08705 c8d3677df8ae81e8163db9312be7d1f5 484 SMART SM00640 25 447 7.3E-119 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CWM22_RS08705 c8d3677df8ae81e8163db9312be7d1f5 484 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 25 333 9.8E-97 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CWM22_RS08705 c8d3677df8ae81e8163db9312be7d1f5 484 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 13 453 2.9E-123 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CWM22_RS08705 c8d3677df8ae81e8163db9312be7d1f5 484 Gene3D G3DSA:2.60.120.560 348 479 1.1E-19 T 28-03-2018 CWM22_RS08705 c8d3677df8ae81e8163db9312be7d1f5 484 SUPERFAMILY SSF49899 333 474 1.19E-18 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CWM22_RS08705 c8d3677df8ae81e8163db9312be7d1f5 484 SUPERFAMILY SSF75005 18 334 4.87E-102 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWM22_RS02665 f181a9ba18fecedf599511650abdcf73 161 Pfam PF03830 PTS system sorbose subfamily IIB component 3 149 7.1E-50 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWM22_RS02665 f181a9ba18fecedf599511650abdcf73 161 SUPERFAMILY SSF52728 1 160 3.14E-53 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWM22_RS02665 f181a9ba18fecedf599511650abdcf73 161 Gene3D G3DSA:3.40.35.10 2 158 3.7E-54 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 CWM22_RS03400 759d650e8eb2292c16c4cdb922421fe5 95 SUPERFAMILY SSF109797 4 82 8.11E-11 T 28-03-2018 CWM22_RS03400 759d650e8eb2292c16c4cdb922421fe5 95 Pfam PF08951 Enterocin A Immunity 8 78 5.2E-6 T 28-03-2018 IPR015046 Enterocin A Immunity CWM22_RS03400 759d650e8eb2292c16c4cdb922421fe5 95 Gene3D G3DSA:1.20.1440.50 4 86 3.2E-17 T 28-03-2018 IPR023130 Ta0600-like domain CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 SUPERFAMILY SSF46785 1 66 9.52E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 Gene3D G3DSA:1.10.10.10 3 66 1.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 Pfam PF02863 Arginine repressor, C-terminal domain 75 134 8.2E-7 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 Pfam PF01316 Arginine repressor, DNA binding domain 1 67 3.6E-22 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 Hamap MF_00173 Arginine repressor [argR]. 1 141 41.849 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 Gene3D G3DSA:3.30.1360.40 67 141 8.1E-10 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 SUPERFAMILY SSF55252 75 140 9.03E-13 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 PRINTS PR01467 Bacterial arginine repressor signature 37 52 1.0E-14 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 PRINTS PR01467 Bacterial arginine repressor signature 81 94 1.0E-14 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 PRINTS PR01467 Bacterial arginine repressor signature 111 126 1.0E-14 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS02960 207783c663b5ec05d2b891d06379a53b 141 PRINTS PR01467 Bacterial arginine repressor signature 21 34 1.0E-14 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWM22_RS01075 7c7f78cab65880a6d359b7fb8d3c7fac 76 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 75 3.0E-37 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CWM22_RS01075 7c7f78cab65880a6d359b7fb8d3c7fac 76 Pfam PF07288 Protein of unknown function (DUF1447) 2 75 1.2E-27 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CWM22_RS04195 2987b2cc7d0ff0a5518fcd741bc38bd3 91 TIGRFAM TIGR01805 CM_mono_grmpos: chorismate mutase 3 83 7.4E-28 T 28-03-2018 IPR011279 Chorismate mutase, Gram-positive CWM22_RS04195 2987b2cc7d0ff0a5518fcd741bc38bd3 91 Pfam PF01817 Chorismate mutase type II 7 83 2.9E-22 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWM22_RS04195 2987b2cc7d0ff0a5518fcd741bc38bd3 91 Gene3D G3DSA:1.20.59.10 1 90 5.6E-25 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWM22_RS04195 2987b2cc7d0ff0a5518fcd741bc38bd3 91 SUPERFAMILY SSF48600 1 84 4.58E-21 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWM22_RS04195 2987b2cc7d0ff0a5518fcd741bc38bd3 91 SMART SM00830 7 86 2.7E-23 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWM22_RS03195 81cd44d3e46c52724c62f49e306135b5 149 SUPERFAMILY SSF46785 10 142 3.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03195 81cd44d3e46c52724c62f49e306135b5 149 Gene3D G3DSA:1.10.10.10 1 144 3.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03195 81cd44d3e46c52724c62f49e306135b5 149 SMART SM00347 24 125 7.6E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS12175 f93adcf8eec4b1d9fd3a8714bb331658 86 Gene3D G3DSA:3.40.1620.10 1 40 1.8E-11 T 28-03-2018 CWM22_RS12175 f93adcf8eec4b1d9fd3a8714bb331658 86 SUPERFAMILY SSF143120 1 82 1.7E-17 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CWM22_RS12175 f93adcf8eec4b1d9fd3a8714bb331658 86 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 75 3.6E-15 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CWM22_RS12175 f93adcf8eec4b1d9fd3a8714bb331658 86 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 54 7.2E-16 T 28-03-2018 CWM22_RS03530 b272fa3ce5127d4582ec4b39a63bf9c9 479 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 244 388 2.5E-39 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWM22_RS03530 b272fa3ce5127d4582ec4b39a63bf9c9 479 Gene3D G3DSA:3.40.190.10 90 214 4.8E-6 T 28-03-2018 CWM22_RS03530 b272fa3ce5127d4582ec4b39a63bf9c9 479 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 244 388 7.6E-26 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWM22_RS03530 b272fa3ce5127d4582ec4b39a63bf9c9 479 Pfam PF02916 DNA polymerase processivity factor 68 183 5.4E-47 T 28-03-2018 IPR004190 DNA polymerase processivity factor GO:0006260 CWM22_RS10365 02c8dc34cbdfd43c7bd977326ec57787 607 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 116 511 3.7E-69 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CWM22_RS10365 02c8dc34cbdfd43c7bd977326ec57787 607 Gene3D G3DSA:3.90.76.10 102 210 7.4E-18 T 28-03-2018 CWM22_RS10365 02c8dc34cbdfd43c7bd977326ec57787 607 Gene3D G3DSA:3.40.190.10 211 359 1.7E-28 T 28-03-2018 CWM22_RS10365 02c8dc34cbdfd43c7bd977326ec57787 607 SUPERFAMILY SSF53850 93 582 2.53E-89 T 28-03-2018 CWM22_RS10365 02c8dc34cbdfd43c7bd977326ec57787 607 PIRSF PIRSF002741 15 594 4.3E-65 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CWM22_RS10365 02c8dc34cbdfd43c7bd977326ec57787 607 Gene3D G3DSA:3.10.105.10 360 566 3.2E-37 T 28-03-2018 CWM22_RS09775 c160932da2e4d15125e352fad98708e2 152 Pfam PF08241 Methyltransferase domain 21 115 6.5E-6 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CWM22_RS09775 c160932da2e4d15125e352fad98708e2 152 SUPERFAMILY SSF53335 3 151 3.78E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS09775 c160932da2e4d15125e352fad98708e2 152 Gene3D G3DSA:3.40.50.150 26 148 1.6E-13 T 28-03-2018 CWM22_RS11515 c27afc890c05ba849de08b56d0d1f386 1252 Gene3D G3DSA:3.40.50.300 1 1234 1.7E-7 T 28-03-2018 CWM22_RS07255 dd6b9a1c26335be5dc12c73e076ecac9 342 Gene3D G3DSA:3.90.1150.10 250 342 3.5E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS07255 dd6b9a1c26335be5dc12c73e076ecac9 342 Pfam PF01212 Beta-eliminating lyase 27 295 2.7E-30 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CWM22_RS07255 dd6b9a1c26335be5dc12c73e076ecac9 342 SUPERFAMILY SSF53383 1 342 8.29E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS07255 dd6b9a1c26335be5dc12c73e076ecac9 342 Gene3D G3DSA:3.40.640.10 1 249 1.0E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS01365 0e28b480ef8c15949d6ceb2259c5d7bd 327 Gene3D G3DSA:3.40.50.720 1 147 2.9E-38 T 28-03-2018 CWM22_RS01365 0e28b480ef8c15949d6ceb2259c5d7bd 327 SUPERFAMILY SSF55347 130 294 1.8E-36 T 28-03-2018 CWM22_RS01365 0e28b480ef8c15949d6ceb2259c5d7bd 327 SUPERFAMILY SSF51735 7 157 1.29E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS01365 0e28b480ef8c15949d6ceb2259c5d7bd 327 Gene3D G3DSA:3.30.360.10 148 327 2.0E-28 T 28-03-2018 CWM22_RS01365 0e28b480ef8c15949d6ceb2259c5d7bd 327 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 122 5.3E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CWM22_RS00945 e8f1d89840fa84c85ae0cbe9f4741c21 900 Gene3D G3DSA:1.10.287.620 26 185 1.5E-4 T 28-03-2018 CWM22_RS00945 e8f1d89840fa84c85ae0cbe9f4741c21 900 SUPERFAMILY SSF57997 601 791 1.44E-6 T 28-03-2018 CWM22_RS00945 e8f1d89840fa84c85ae0cbe9f4741c21 900 Gene3D G3DSA:1.20.1170.10 337 793 2.7E-15 T 28-03-2018 CWM22_RS00945 e8f1d89840fa84c85ae0cbe9f4741c21 900 Pfam PF00746 LPXTG cell wall anchor motif 865 898 9.9E-6 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS00945 e8f1d89840fa84c85ae0cbe9f4741c21 900 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 257 655 3.7E-56 T 28-03-2018 IPR027607 SEC10/PgrA surface exclusion domain CWM22_RS00945 e8f1d89840fa84c85ae0cbe9f4741c21 900 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 867 898 4.9E-7 T 28-03-2018 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 116 249 3.3E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 Gene3D G3DSA:1.10.8.60 258 392 5.1E-30 T 28-03-2018 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 606 676 8.7E-22 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 521 539 7.0E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 446 464 7.0E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 554 568 7.0E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 491 509 7.0E-28 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 476 494 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 SMART SM00382 442 607 3.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 SMART SM00382 111 258 1.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 Gene3D G3DSA:3.40.50.300 415 611 2.9E-33 T 28-03-2018 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 Gene3D G3DSA:1.10.8.60 612 697 1.7E-21 T 28-03-2018 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 SMART SM01086 606 693 3.7E-28 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 Gene3D G3DSA:3.40.50.300 71 257 1.3E-27 T 28-03-2018 CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 SUPERFAMILY SSF52540 74 350 7.34E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 SUPERFAMILY SSF52540 391 674 2.56E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02325 c35bf6a6d4bf8e7fb05b0684120f31f3 699 Pfam PF07724 AAA domain (Cdc48 subfamily) 441 599 3.3E-41 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWM22_RS03085 4b81adca480ff02f214499bda6b3b1a4 344 PIRSF PIRSF001123 1 342 2.1E-35 T 28-03-2018 IPR008007 Peptidase M42 CWM22_RS03085 4b81adca480ff02f214499bda6b3b1a4 344 Pfam PF05343 M42 glutamyl aminopeptidase 44 333 2.7E-85 T 28-03-2018 IPR008007 Peptidase M42 CWM22_RS03085 4b81adca480ff02f214499bda6b3b1a4 344 SUPERFAMILY SSF101821 69 182 9.01E-29 T 28-03-2018 CWM22_RS03085 4b81adca480ff02f214499bda6b3b1a4 344 Gene3D G3DSA:3.40.630.10 2 342 4.9E-42 T 28-03-2018 CWM22_RS03085 4b81adca480ff02f214499bda6b3b1a4 344 SUPERFAMILY SSF53187 1 81 8.31E-53 T 28-03-2018 CWM22_RS03085 4b81adca480ff02f214499bda6b3b1a4 344 SUPERFAMILY SSF53187 177 340 8.31E-53 T 28-03-2018 CWM22_RS10980 04fa37367f8e402778660dc2fcdc9122 119 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 116 9.4E-22 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWM22_RS10980 04fa37367f8e402778660dc2fcdc9122 119 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 21.177 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWM22_RS10980 04fa37367f8e402778660dc2fcdc9122 119 SUPERFAMILY SSF56214 1 115 3.92E-32 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CWM22_RS10980 04fa37367f8e402778660dc2fcdc9122 119 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 6 100 3.0E-19 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CWM22_RS10980 04fa37367f8e402778660dc2fcdc9122 119 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 116 2.3E-19 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWM22_RS10980 04fa37367f8e402778660dc2fcdc9122 119 Gene3D G3DSA:3.90.470.20 1 119 5.3E-29 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CWM22_RS10980 04fa37367f8e402778660dc2fcdc9122 119 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 116 3.0E-57 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWM22_RS04835 c6e05c796abb0f4d1c04628da129eb70 1036 Gene3D G3DSA:2.40.50.140 871 968 4.6E-13 T 28-03-2018 CWM22_RS04835 c6e05c796abb0f4d1c04628da129eb70 1036 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 243 661 7.9E-157 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS04835 c6e05c796abb0f4d1c04628da129eb70 1036 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 157 927 5.1E-206 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS04835 c6e05c796abb0f4d1c04628da129eb70 1036 SUPERFAMILY SSF89550 9 77 1.26E-7 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWM22_RS04835 c6e05c796abb0f4d1c04628da129eb70 1036 Pfam PF14579 Helix-hairpin-helix motif 731 812 4.0E-8 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWM22_RS04835 c6e05c796abb0f4d1c04628da129eb70 1036 Pfam PF01336 OB-fold nucleic acid binding domain 897 966 6.5E-8 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWM22_RS04835 c6e05c796abb0f4d1c04628da129eb70 1036 Pfam PF02811 PHP domain 7 103 6.7E-18 T 28-03-2018 IPR004013 PHP domain GO:0003824 CWM22_RS04835 c6e05c796abb0f4d1c04628da129eb70 1036 SMART SM00481 3 70 6.3E-11 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWM22_RS04835 c6e05c796abb0f4d1c04628da129eb70 1036 Gene3D G3DSA:3.20.20.140 1 277 4.0E-17 T 28-03-2018 CWM22_RS06540 0b74a963fe0f2956ba71ac033a70e0c5 835 SUPERFAMILY SSF89550 97 299 6.67E-8 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWM22_RS06540 0b74a963fe0f2956ba71ac033a70e0c5 835 Gene3D G3DSA:3.40.50.300 329 817 1.1E-23 T 28-03-2018 CWM22_RS06540 0b74a963fe0f2956ba71ac033a70e0c5 835 SUPERFAMILY SSF52540 338 531 8.18E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06540 0b74a963fe0f2956ba71ac033a70e0c5 835 SUPERFAMILY SSF52540 685 789 8.18E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS06540 0b74a963fe0f2956ba71ac033a70e0c5 835 Gene3D G3DSA:3.20.20.140 26 284 2.1E-6 T 28-03-2018 CWM22_RS12545 108f8a8763c41d1d0b5fdc73b8bb45ec 79 Gene3D G3DSA:3.40.50.300 1 79 7.5E-20 T 28-03-2018 CWM22_RS12545 108f8a8763c41d1d0b5fdc73b8bb45ec 79 SUPERFAMILY SSF52540 1 75 6.51E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12370 ddff0cdc8b28411be4d70a6f00f5b0d8 96 Gene3D G3DSA:1.20.1440.50 5 81 2.6E-6 T 28-03-2018 IPR023130 Ta0600-like domain CWM22_RS12370 ddff0cdc8b28411be4d70a6f00f5b0d8 96 Pfam PF08951 Enterocin A Immunity 9 75 2.4E-6 T 28-03-2018 IPR015046 Enterocin A Immunity CWM22_RS11795 2eab3a4cdf6f846f903f97f7cae060f6 261 SUPERFAMILY SSF55821 224 236 2.87E-21 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWM22_RS11795 2eab3a4cdf6f846f903f97f7cae060f6 261 SUPERFAMILY SSF55821 6 196 2.87E-21 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWM22_RS11795 2eab3a4cdf6f846f903f97f7cae060f6 261 Pfam PF01300 Telomere recombination 22 197 1.1E-9 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CWM22_RS11795 2eab3a4cdf6f846f903f97f7cae060f6 261 Gene3D G3DSA:3.90.870.10 10 202 7.7E-23 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWM22_RS09035 9609344f2bf35f499f63601d20a3d7d5 140 Gene3D G3DSA:2.40.50.140 1 117 8.9E-21 T 28-03-2018 CWM22_RS09035 9609344f2bf35f499f63601d20a3d7d5 140 SUPERFAMILY SSF50249 7 140 1.99E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS09035 9609344f2bf35f499f63601d20a3d7d5 140 Pfam PF00436 Single-strand binding protein family 1 97 8.3E-14 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWM22_RS09035 9609344f2bf35f499f63601d20a3d7d5 140 PIRSF PIRSF002070 1 138 3.4E-21 T 28-03-2018 CWM22_RS05680 ba566e30076764b870a694aaa1109e8d 168 Gene3D G3DSA:3.40.50.300 4 164 1.5E-16 T 28-03-2018 CWM22_RS05680 ba566e30076764b870a694aaa1109e8d 168 SUPERFAMILY SSF52540 29 161 2.65E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS05680 ba566e30076764b870a694aaa1109e8d 168 Pfam PF06414 Zeta toxin 25 161 2.0E-38 T 28-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 CWM22_RS06410 ba999ce77365841c94b3372d327f0231 124 Pfam PF14198 Transposon-encoded protein TnpV 12 122 2.9E-43 T 28-03-2018 IPR026989 Transposon-encoded protein TnpV CWM22_RS05240 b46c745517e7a8405088d8fe4afbe483 182 Pfam PF02397 Bacterial sugar transferase 2 168 1.3E-51 T 28-03-2018 IPR003362 Bacterial sugar transferase CWM22_RS13270 660cfdfe6259fe06529a51e6b3aa51c1 150 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWM22_RS13270 660cfdfe6259fe06529a51e6b3aa51c1 150 SUPERFAMILY SSF55811 7 132 2.57E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS13270 660cfdfe6259fe06529a51e6b3aa51c1 150 Gene3D G3DSA:3.90.79.10 1 149 1.1E-22 T 28-03-2018 CWM22_RS13270 660cfdfe6259fe06529a51e6b3aa51c1 150 Pfam PF00293 NUDIX domain 15 127 1.6E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWM22_RS11485 b28dfebd7f9ac17c5210ad0e9f79e6e1 115 SUPERFAMILY SSF117916 13 109 8.83E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CWM22_RS11485 b28dfebd7f9ac17c5210ad0e9f79e6e1 115 Pfam PF01883 Iron-sulfur cluster assembly protein 16 89 2.5E-13 T 28-03-2018 IPR002744 MIP18 family-like CWM22_RS11485 b28dfebd7f9ac17c5210ad0e9f79e6e1 115 Gene3D G3DSA:3.30.300.130 12 110 1.1E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CWM22_RS04190 3de4066602871f26d9798f2c0cfeb702 404 Pfam PF00654 Voltage gated chloride channel 54 384 7.7E-50 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS04190 3de4066602871f26d9798f2c0cfeb702 404 Gene3D G3DSA:1.10.3080.10 2 396 1.6E-41 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS04190 3de4066602871f26d9798f2c0cfeb702 404 SUPERFAMILY SSF81340 6 396 1.19E-61 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CWM22_RS03300 eeee7db76f3928149339c1404afb4f25 181 SUPERFAMILY SSF55811 6 180 8.39E-50 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS03300 eeee7db76f3928149339c1404afb4f25 181 Pfam PF00293 NUDIX domain 43 158 2.4E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWM22_RS03300 eeee7db76f3928149339c1404afb4f25 181 Gene3D G3DSA:3.90.79.10 1 181 6.6E-41 T 28-03-2018 CWM22_RS03300 eeee7db76f3928149339c1404afb4f25 181 PRINTS PR00502 NUDIX hydrolase family signature 87 102 1.4E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWM22_RS03300 eeee7db76f3928149339c1404afb4f25 181 PRINTS PR00502 NUDIX hydrolase family signature 71 85 1.4E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWM22_RS07510 8dc04f37d185486c1eb1b20190474de1 433 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 11 428 3.4E-114 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWM22_RS07510 8dc04f37d185486c1eb1b20190474de1 433 Pfam PF02378 Phosphotransferase system, EIIC 26 356 2.2E-66 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWM22_RS07510 8dc04f37d185486c1eb1b20190474de1 433 PIRSF PIRSF006351 1 432 9.8E-126 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWM22_RS10565 6b5ff67373b638835729844a1f52fa0c 74 Pfam PF13268 Protein of unknown function (DUF4059) 1 72 1.2E-33 T 28-03-2018 IPR025134 Protein of unknown function DUF4059 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.1180 2638 2771 2.0E-10 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 SUPERFAMILY SSF49478 3179 3240 4.71E-5 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 SUPERFAMILY SSF49785 1786 1903 5.36E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.1140 2786 2905 5.5E-6 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.1140 721 820 6.7E-5 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.10 1231 1328 2.0E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.10 1329 1435 1.0E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.10 1926 2042 2.3E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.10 277 430 7.6E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.10 2173 2299 1.4E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.10 1663 1765 6.1E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.10 2533 2637 1.2E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.10 1542 1662 1.3E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 SUPERFAMILY SSF49401 864 961 1.86E-6 T 28-03-2018 IPR008966 Adhesion domain CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 SUPERFAMILY SSF49478 1242 1300 2.63E-7 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 2050 2164 7.4E-13 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 2411 2532 3.2E-15 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 2300 2410 5.0E-18 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 2908 3015 3.1E-14 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 3164 3263 3.7E-18 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 3265 3396 1.3E-13 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 3020 3163 1.2E-9 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 3397 3509 9.3E-12 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 3510 3630 3.4E-13 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.40.810 1436 1538 4.3E-14 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 SUPERFAMILY SSF49478 2322 2378 1.61E-6 T 28-03-2018 CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 SUPERFAMILY SSF49785 2676 2764 5.36E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Pfam PF00754 F5/8 type C domain 1785 1899 2.2E-10 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Pfam PF00754 F5/8 type C domain 2652 2762 1.6E-7 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CWM22_RS08545 8a089e3c9da00f206c85cefb086eef95 3675 Gene3D G3DSA:2.60.120.260 1766 1909 5.7E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS07380 77c39dd2404ab33777036d71ef25bcfb 251 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 106 227 5.2E-34 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CWM22_RS07380 77c39dd2404ab33777036d71ef25bcfb 251 SUPERFAMILY SSF55166 106 230 7.46E-26 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWM22_RS07380 77c39dd2404ab33777036d71ef25bcfb 251 Gene3D G3DSA:3.30.1380.10 94 225 6.1E-28 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWM22_RS08070 b751c37746d7e1a327f35ef766b6d38b 173 Pfam PF13673 Acetyltransferase (GNAT) domain 27 152 3.1E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS08070 b751c37746d7e1a327f35ef766b6d38b 173 SUPERFAMILY SSF55729 1 163 2.99E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS08070 b751c37746d7e1a327f35ef766b6d38b 173 Gene3D G3DSA:3.40.630.30 1 173 5.9E-30 T 28-03-2018 CWM22_RS11845 8950a041430d38018f2dd27c94fc91a6 181 Gene3D G3DSA:1.10.10.60 45 176 1.3E-6 T 28-03-2018 CWM22_RS11845 8950a041430d38018f2dd27c94fc91a6 181 Pfam PF14278 Transcriptional regulator C-terminal region 78 153 7.5E-9 T 28-03-2018 CWM22_RS11845 8950a041430d38018f2dd27c94fc91a6 181 TIGRFAM TIGR02366 DHAK_reg: probable dihydroxyacetone kinase regulator 4 176 3.9E-61 T 28-03-2018 IPR012738 Transcription regulator DhaS CWM22_RS11845 8950a041430d38018f2dd27c94fc91a6 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 51 2.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWM22_RS11845 8950a041430d38018f2dd27c94fc91a6 181 Gene3D G3DSA:1.10.10.60 3 44 1.1E-9 T 28-03-2018 CWM22_RS11845 8950a041430d38018f2dd27c94fc91a6 181 SUPERFAMILY SSF46689 4 64 5.64E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWM22_RS06125 4d69de7536ca0edfa1096a10196d1891 198 Pfam PF14283 Domain of unknown function (DUF4366) 69 178 1.5E-15 T 28-03-2018 IPR025376 Domain of unknown function DUF4366 CWM22_RS04540 fffeb242a3aeb6089ecf0af64633408b 158 Pfam PF01381 Helix-turn-helix 7 61 3.7E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS04540 fffeb242a3aeb6089ecf0af64633408b 158 Gene3D G3DSA:1.10.3100.10 1 94 2.7E-21 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS04540 fffeb242a3aeb6089ecf0af64633408b 158 Pfam PF13127 Protein of unknown function (DUF3955) 92 148 8.7E-21 T 28-03-2018 IPR025016 Protein of unknown function DUF3955 CWM22_RS04540 fffeb242a3aeb6089ecf0af64633408b 158 SMART SM00530 6 61 6.4E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS04540 fffeb242a3aeb6089ecf0af64633408b 158 SUPERFAMILY SSF47413 1 69 2.95E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS05510 1802dd09fd60a5f1f8113ccdd68534c9 194 Pfam PF02517 CAAX protease self-immunity 102 186 5.9E-13 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS06310 1802dd09fd60a5f1f8113ccdd68534c9 194 Pfam PF02517 CAAX protease self-immunity 102 186 5.9E-13 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS11960 b46739483c5a00e8e98e30ed598b3b6b 58 Gene3D G3DSA:1.20.5.1030 1 51 1.8E-13 T 28-03-2018 CWM22_RS11960 b46739483c5a00e8e98e30ed598b3b6b 58 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 2 54 2.8E-11 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CWM22_RS11960 b46739483c5a00e8e98e30ed598b3b6b 58 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 2 52 7.0E-13 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWM22_RS05800 d0e72ac9d498c10b1df847e95fabb54e 355 Pfam PF07751 Abi-like protein 86 269 2.5E-24 T 28-03-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 TIGRFAM TIGR00062 L27: ribosomal protein bL27 12 92 4.8E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 39 80 1.0E-16 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 SUPERFAMILY SSF110324 13 94 1.74E-31 T 28-03-2018 CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 ProSitePatterns PS00831 Ribosomal protein L27 signature. 45 59 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 Gene3D G3DSA:2.40.50.100 31 95 5.0E-28 T 28-03-2018 CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 PRINTS PR00063 Ribosomal protein L27 signature 65 89 1.2E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 PRINTS PR00063 Ribosomal protein L27 signature 40 64 1.2E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 PRINTS PR00063 Ribosomal protein L27 signature 15 39 1.2E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 Pfam PF01016 Ribosomal L27 protein 13 92 7.2E-34 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS07220 5ff32bd9d8159b428956652a0465309c 97 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 12 95 26.931 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04865 3768c9392d4294faa24e9ff6046b7800 369 SUPERFAMILY SSF51905 3 218 2.07E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS04865 3768c9392d4294faa24e9ff6046b7800 369 SUPERFAMILY SSF51905 308 366 2.07E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS04865 3768c9392d4294faa24e9ff6046b7800 369 Gene3D G3DSA:3.30.9.10 190 307 1.7E-23 T 28-03-2018 CWM22_RS04865 3768c9392d4294faa24e9ff6046b7800 369 SUPERFAMILY SSF54373 218 307 2.09E-15 T 28-03-2018 CWM22_RS04865 3768c9392d4294faa24e9ff6046b7800 369 Gene3D G3DSA:3.50.50.60 1 189 4.0E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS04865 3768c9392d4294faa24e9ff6046b7800 369 Pfam PF01266 FAD dependent oxidoreductase 5 345 4.1E-47 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CWM22_RS10415 c895186c357dcfb07834641d68677dea 80 Hamap MF_00363 UPF0154 protein . 4 74 19.453 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CWM22_RS10415 c895186c357dcfb07834641d68677dea 80 Pfam PF03672 Uncharacterised protein family (UPF0154) 13 70 9.2E-22 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CWM22_RS10415 c895186c357dcfb07834641d68677dea 80 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 25 64 2.0E-8 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CWM22_RS07525 70d666c7ae1a3aefc4a424ba6777f262 323 SUPERFAMILY SSF46785 12 64 6.54E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS07525 70d666c7ae1a3aefc4a424ba6777f262 323 SUPERFAMILY SSF100950 60 316 5.12E-66 T 28-03-2018 CWM22_RS07525 70d666c7ae1a3aefc4a424ba6777f262 323 Gene3D G3DSA:1.10.10.60 1 53 1.4E-16 T 28-03-2018 CWM22_RS07525 70d666c7ae1a3aefc4a424ba6777f262 323 Pfam PF13384 Homeodomain-like domain 2 49 2.9E-6 T 28-03-2018 CWM22_RS07525 70d666c7ae1a3aefc4a424ba6777f262 323 Pfam PF04198 Putative sugar-binding domain 62 313 2.0E-71 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CWM22_RS07525 70d666c7ae1a3aefc4a424ba6777f262 323 Gene3D G3DSA:3.40.50.1360 54 318 7.4E-33 T 28-03-2018 CWM22_RS03800 a4781c94fd2863474a58906da684da79 318 SUPERFAMILY SSF52833 42 161 1.15E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS03800 a4781c94fd2863474a58906da684da79 318 Gene3D G3DSA:1.20.1050.10 188 317 6.2E-45 T 28-03-2018 CWM22_RS03800 a4781c94fd2863474a58906da684da79 318 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 157 1.6E-23 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CWM22_RS03800 a4781c94fd2863474a58906da684da79 318 PIRSF PIRSF015753 5 318 1.4E-136 T 28-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 CWM22_RS03800 a4781c94fd2863474a58906da684da79 318 Gene3D G3DSA:3.40.30.10 38 187 1.9E-37 T 28-03-2018 CWM22_RS03800 a4781c94fd2863474a58906da684da79 318 Pfam PF13410 Glutathione S-transferase, C-terminal domain 204 275 1.5E-13 T 28-03-2018 CWM22_RS03800 a4781c94fd2863474a58906da684da79 318 SUPERFAMILY SSF47616 175 317 3.2E-38 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CWM22_RS08680 3493f2c4600da12d05955c28d02975ea 538 SUPERFAMILY SSF51445 7 463 8.26E-148 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS08680 3493f2c4600da12d05955c28d02975ea 538 Pfam PF00128 Alpha amylase, catalytic domain 32 362 2.8E-116 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS08680 3493f2c4600da12d05955c28d02975ea 538 Gene3D G3DSA:3.90.400.10 124 168 1.9E-22 T 28-03-2018 CWM22_RS08680 3493f2c4600da12d05955c28d02975ea 538 Gene3D G3DSA:3.20.20.80 333 459 5.1E-19 T 28-03-2018 CWM22_RS08680 3493f2c4600da12d05955c28d02975ea 538 Gene3D G3DSA:3.20.20.470 169 332 1.5E-35 T 28-03-2018 CWM22_RS08680 3493f2c4600da12d05955c28d02975ea 538 SMART SM00642 17 405 7.2E-142 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWM22_RS08680 3493f2c4600da12d05955c28d02975ea 538 Gene3D G3DSA:2.60.40.1180 460 537 1.3E-11 T 28-03-2018 CWM22_RS08680 3493f2c4600da12d05955c28d02975ea 538 Gene3D G3DSA:3.20.20.80 2 123 1.4E-46 T 28-03-2018 CWM22_RS08680 3493f2c4600da12d05955c28d02975ea 538 SUPERFAMILY SSF51011 466 537 3.02E-11 T 28-03-2018 CWM22_RS01265 599749c2df8e9b486060081b33985b69 781 Pfam PF01228 Glycine radical 648 747 2.1E-21 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CWM22_RS01265 599749c2df8e9b486060081b33985b69 781 ProSitePatterns PS00850 Glycine radical domain signature. 738 746 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CWM22_RS01265 599749c2df8e9b486060081b33985b69 781 Pfam PF02901 Pyruvate formate lyase-like 35 618 6.4E-153 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CWM22_RS01265 599749c2df8e9b486060081b33985b69 781 PIRSF PIRSF000379 15 768 8.9E-287 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CWM22_RS01265 599749c2df8e9b486060081b33985b69 781 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 18 768 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CWM22_RS01265 599749c2df8e9b486060081b33985b69 781 Gene3D G3DSA:3.20.70.20 9 768 1.9E-193 T 28-03-2018 CWM22_RS01265 599749c2df8e9b486060081b33985b69 781 SUPERFAMILY SSF51998 12 767 1.46E-197 T 28-03-2018 CWM22_RS12820 65c41cdf39b2b6614585c70b476a7e5a 245 Pfam PF00746 LPXTG cell wall anchor motif 199 229 1.8E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS12820 65c41cdf39b2b6614585c70b476a7e5a 245 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 203 233 6.3E-6 T 28-03-2018 CWM22_RS04565 e4f313d7b708b6c0ecac5e38232a419f 234 Pfam PF07949 YbbR-like protein 150 216 6.8E-14 T 28-03-2018 IPR012505 YbbR-like CWM22_RS04565 e4f313d7b708b6c0ecac5e38232a419f 234 Pfam PF07949 YbbR-like protein 52 135 7.9E-12 T 28-03-2018 IPR012505 YbbR-like CWM22_RS09275 5f83a4a4705c5f5f1a8d408f6a5c13e9 672 Pfam PF03747 ADP-ribosylglycohydrolase 1 227 1.4E-27 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CWM22_RS09275 5f83a4a4705c5f5f1a8d408f6a5c13e9 672 Gene3D G3DSA:1.10.4080.10 1 244 1.7E-42 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CWM22_RS09275 5f83a4a4705c5f5f1a8d408f6a5c13e9 672 Gene3D G3DSA:1.20.5.340 474 671 7.5E-4 T 28-03-2018 CWM22_RS09275 5f83a4a4705c5f5f1a8d408f6a5c13e9 672 Gene3D G3DSA:1.20.120.20 318 473 5.5E-5 T 28-03-2018 CWM22_RS09275 5f83a4a4705c5f5f1a8d408f6a5c13e9 672 SUPERFAMILY SSF101478 1 235 1.96E-45 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CWM22_RS07040 a6cee2cd4798ac0a7303acd05eb5cf9a 202 Gene3D G3DSA:3.40.50.300 1 200 5.0E-59 T 28-03-2018 CWM22_RS07040 a6cee2cd4798ac0a7303acd05eb5cf9a 202 Pfam PF00005 ABC transporter 18 154 5.0E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS07040 a6cee2cd4798ac0a7303acd05eb5cf9a 202 SUPERFAMILY SSF52540 1 199 1.78E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07040 a6cee2cd4798ac0a7303acd05eb5cf9a 202 SMART SM00382 26 200 4.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS07040 a6cee2cd4798ac0a7303acd05eb5cf9a 202 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS00215 f653f443970b243129323b796b75dc27 392 Pfam PF00155 Aminotransferase class I and II 32 382 1.5E-58 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWM22_RS00215 f653f443970b243129323b796b75dc27 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 93 113 1.3E-12 T 28-03-2018 CWM22_RS00215 f653f443970b243129323b796b75dc27 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 164 188 1.3E-12 T 28-03-2018 CWM22_RS00215 f653f443970b243129323b796b75dc27 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 200 223 1.3E-12 T 28-03-2018 CWM22_RS00215 f653f443970b243129323b796b75dc27 392 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 115 136 1.3E-12 T 28-03-2018 CWM22_RS00215 f653f443970b243129323b796b75dc27 392 Gene3D G3DSA:3.90.1150.10 300 390 1.0E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS00215 f653f443970b243129323b796b75dc27 392 SUPERFAMILY SSF53383 6 388 7.45E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS00215 f653f443970b243129323b796b75dc27 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CWM22_RS00215 f653f443970b243129323b796b75dc27 392 Gene3D G3DSA:3.40.640.10 45 299 4.5E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS09265 068ca37962e1def1b8504ac11881c9e9 154 Pfam PF01797 Transposase IS200 like 13 130 2.0E-39 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS09265 068ca37962e1def1b8504ac11881c9e9 154 SUPERFAMILY SSF143422 4 131 1.7E-48 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS09265 068ca37962e1def1b8504ac11881c9e9 154 Gene3D G3DSA:3.30.70.1290 3 136 4.2E-27 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS09265 068ca37962e1def1b8504ac11881c9e9 154 ProDom PD012638 PLASMID PGP2-D VIRULENCE P-4 DNA 33 84 0.004 T 28-03-2018 CWM22_RS09265 068ca37962e1def1b8504ac11881c9e9 154 SMART SM01321 12 130 4.3E-45 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS10660 4aaa786ea52841fbef9440f3ffaaf2fe 159 Gene3D G3DSA:3.40.190.10 1 156 4.4E-7 T 28-03-2018 CWM22_RS10660 4aaa786ea52841fbef9440f3ffaaf2fe 159 Pfam PF04205 FMN-binding domain 56 145 6.1E-6 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CWM22_RS10660 4aaa786ea52841fbef9440f3ffaaf2fe 159 SMART SM00900 57 148 2.1E-10 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CWM22_RS01940 82294382c964ca8c95fd35355a68dded 153 Pfam PF01475 Ferric uptake regulator family 24 143 1.7E-35 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CWM22_RS01940 82294382c964ca8c95fd35355a68dded 153 Gene3D G3DSA:1.10.10.10 1 97 2.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01940 82294382c964ca8c95fd35355a68dded 153 SUPERFAMILY SSF46785 17 148 9.62E-39 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08050 74bf10f3570f9ad236a280368868a41e 247 SUPERFAMILY SSF55154 14 231 8.72E-5 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CWM22_RS08050 74bf10f3570f9ad236a280368868a41e 247 Gene3D G3DSA:2.40.320.10 6 223 2.2E-31 T 28-03-2018 CWM22_RS08050 74bf10f3570f9ad236a280368868a41e 247 Pfam PF09359 VTC domain 11 234 9.2E-39 T 28-03-2018 IPR018966 VTC domain CWM22_RS07965 e4cb83abcaea45c14fd6fb82356b7bbe 309 SUPERFAMILY SSF56281 1 309 1.76E-81 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS07965 e4cb83abcaea45c14fd6fb82356b7bbe 309 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 309 2.4E-108 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CWM22_RS07965 e4cb83abcaea45c14fd6fb82356b7bbe 309 Pfam PF12706 Beta-lactamase superfamily domain 206 275 3.4E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS07965 e4cb83abcaea45c14fd6fb82356b7bbe 309 Hamap MF_01818 Ribonuclease BN [rbn]. 1 309 39.662 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CWM22_RS07965 e4cb83abcaea45c14fd6fb82356b7bbe 309 Gene3D G3DSA:3.60.15.10 1 309 1.8E-57 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS07965 e4cb83abcaea45c14fd6fb82356b7bbe 309 Pfam PF00753 Metallo-beta-lactamase superfamily 34 93 1.6E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS05070 e54567a060877672a30d10e4ff5c4987 223 Gene3D G3DSA:3.40.50.2300 1 122 1.3E-28 T 28-03-2018 CWM22_RS05070 e54567a060877672a30d10e4ff5c4987 223 SMART SM00448 2 112 1.3E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS05070 e54567a060877672a30d10e4ff5c4987 223 Pfam PF00072 Response regulator receiver domain 4 112 3.3E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWM22_RS05070 e54567a060877672a30d10e4ff5c4987 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 1.9E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS05070 e54567a060877672a30d10e4ff5c4987 223 Gene3D G3DSA:1.10.10.10 123 223 9.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05070 e54567a060877672a30d10e4ff5c4987 223 SUPERFAMILY SSF52172 1 175 1.66E-35 T 28-03-2018 IPR011006 CheY-like superfamily CWM22_RS05070 e54567a060877672a30d10e4ff5c4987 223 SMART SM00862 145 220 6.0E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWM22_RS08145 298775d7c207a2a2ca7de0e68bfffdfe 427 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 419 6.7E-166 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08145 298775d7c207a2a2ca7de0e68bfffdfe 427 SUPERFAMILY SSF55205 8 422 1.42E-134 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CWM22_RS08145 298775d7c207a2a2ca7de0e68bfffdfe 427 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 420 43.21 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWM22_RS08145 298775d7c207a2a2ca7de0e68bfffdfe 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 11 410 5.3E-106 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS08145 298775d7c207a2a2ca7de0e68bfffdfe 427 Gene3D G3DSA:3.65.10.10 224 422 8.2E-46 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS08145 298775d7c207a2a2ca7de0e68bfffdfe 427 Gene3D G3DSA:3.65.10.10 22 223 1.9E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWM22_RS07375 f6283683e6f92e3a99d451494e56cf4f 147 SUPERFAMILY SSF54593 7 136 1.59E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS07375 f6283683e6f92e3a99d451494e56cf4f 147 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 8 132 2.7E-12 T 28-03-2018 IPR028973 PhnB-like CWM22_RS07375 f6283683e6f92e3a99d451494e56cf4f 147 Gene3D G3DSA:3.10.180.10 1 144 8.5E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS07305 7605a1d05e3e829e0ec8b131bcd730a2 200 Pfam PF02661 Fic/DOC family 46 130 3.1E-12 T 28-03-2018 IPR003812 Fido domain CWM22_RS07305 7605a1d05e3e829e0ec8b131bcd730a2 200 Gene3D G3DSA:1.10.3290.10 9 172 9.4E-31 T 28-03-2018 IPR003812 Fido domain CWM22_RS07305 7605a1d05e3e829e0ec8b131bcd730a2 200 SUPERFAMILY SSF140931 19 190 1.57E-37 T 28-03-2018 IPR003812 Fido domain CWM22_RS08575 b6563d97e761eabce1d9c19ca93670cf 363 SUPERFAMILY SSF53383 3 360 2.04E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS08575 b6563d97e761eabce1d9c19ca93670cf 363 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 3 361 1.5E-144 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CWM22_RS08575 b6563d97e761eabce1d9c19ca93670cf 363 Gene3D G3DSA:3.90.1150.10 260 361 1.4E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS08575 b6563d97e761eabce1d9c19ca93670cf 363 Pfam PF00266 Aminotransferase class-V 3 343 1.2E-45 T 28-03-2018 IPR000192 Aminotransferase class V domain CWM22_RS08575 b6563d97e761eabce1d9c19ca93670cf 363 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 1 362 48.203 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CWM22_RS08575 b6563d97e761eabce1d9c19ca93670cf 363 Gene3D G3DSA:3.40.640.10 15 259 2.1E-24 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS08575 b6563d97e761eabce1d9c19ca93670cf 363 PIRSF PIRSF000525 1 363 1.9E-141 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CWM22_RS06245 045805bc26ed7c695b5bb5e2cd611f95 627 Gene3D G3DSA:3.20.20.70 212 550 4.7E-15 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS06245 045805bc26ed7c695b5bb5e2cd611f95 627 SUPERFAMILY SSF51445 221 541 4.91E-21 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS07620 9f1240e2a28346fa7b0b646b97dad1f1 345 PIRSF PIRSF001361 1 345 1.4E-114 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CWM22_RS07620 9f1240e2a28346fa7b0b646b97dad1f1 345 Gene3D G3DSA:3.20.20.70 8 345 4.3E-86 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS07620 9f1240e2a28346fa7b0b646b97dad1f1 345 SUPERFAMILY SSF51569 8 344 2.2E-95 T 28-03-2018 CWM22_RS07620 9f1240e2a28346fa7b0b646b97dad1f1 345 Pfam PF00793 DAHP synthetase I family 38 338 3.4E-50 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CWM22_RS07620 9f1240e2a28346fa7b0b646b97dad1f1 345 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 18 343 3.4E-76 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CWM22_RS11385 76d35fd7832f1ff1169d0ac8459e87bc 146 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 139 1.2E-54 T 28-03-2018 CWM22_RS11385 76d35fd7832f1ff1169d0ac8459e87bc 146 Gene3D G3DSA:3.90.1010.10 3 140 3.4E-45 T 28-03-2018 CWM22_RS11385 76d35fd7832f1ff1169d0ac8459e87bc 146 SUPERFAMILY SSF82649 2 142 6.02E-48 T 28-03-2018 CWM22_RS11385 76d35fd7832f1ff1169d0ac8459e87bc 146 Pfam PF01592 NifU-like N terminal domain 10 127 2.2E-26 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CWM22_RS10400 ace3138a3d1e1e098bef11a9a63c8a91 175 SUPERFAMILY SSF56300 7 171 9.11E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS10400 ace3138a3d1e1e098bef11a9a63c8a91 175 Gene3D G3DSA:3.60.21.10 2 175 7.4E-22 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWM22_RS10400 ace3138a3d1e1e098bef11a9a63c8a91 175 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 8 149 2.1E-22 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CWM22_RS10400 ace3138a3d1e1e098bef11a9a63c8a91 175 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 7 138 6.6E-23 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CWM22_RS13170 d8573c138c30182325618a71686e6fee 312 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 251 306 4.5E-18 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CWM22_RS13170 d8573c138c30182325618a71686e6fee 312 PIRSF PIRSF006483 21 312 5.8E-98 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWM22_RS13170 d8573c138c30182325618a71686e6fee 312 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 42 245 1.7E-58 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWM22_RS00830 098b4094478cea8d542efbf129ba6855 155 PIRSF PIRSF019455 3 136 4.7E-51 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWM22_RS00830 098b4094478cea8d542efbf129ba6855 155 Pfam PF03965 Penicillinase repressor 11 125 2.7E-30 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWM22_RS00830 098b4094478cea8d542efbf129ba6855 155 TIGRFAM TIGR02698 CopY_TcrY: copper transport repressor, CopY/TcrY family 10 139 1.1E-39 T 28-03-2018 IPR014071 Copper transport repressor CopY/TcrY CWM22_RS00830 098b4094478cea8d542efbf129ba6855 155 SUPERFAMILY SSF46785 10 126 3.85E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS00830 098b4094478cea8d542efbf129ba6855 155 Gene3D G3DSA:1.10.10.10 12 74 4.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS11030 b4ea57104dd1630a199d9f1566acffd6 353 Gene3D G3DSA:3.40.350.10 1 111 6.1E-25 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWM22_RS11030 b4ea57104dd1630a199d9f1566acffd6 353 Pfam PF00557 Metallopeptidase family M24 135 337 3.5E-62 T 28-03-2018 IPR000994 Peptidase M24 CWM22_RS11030 b4ea57104dd1630a199d9f1566acffd6 353 Gene3D G3DSA:3.90.230.10 112 353 2.7E-80 T 28-03-2018 CWM22_RS11030 b4ea57104dd1630a199d9f1566acffd6 353 SUPERFAMILY SSF55920 95 348 1.96E-78 T 28-03-2018 IPR000994 Peptidase M24 CWM22_RS11030 b4ea57104dd1630a199d9f1566acffd6 353 SUPERFAMILY SSF53092 1 126 1.69E-26 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWM22_RS11030 b4ea57104dd1630a199d9f1566acffd6 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 284 296 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CWM22_RS11030 b4ea57104dd1630a199d9f1566acffd6 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 3.5E-24 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWM22_RS10140 3cf4ff472704253f295816c1017e22f4 311 SUPERFAMILY SSF64182 3 310 6.02E-81 T 28-03-2018 CWM22_RS10140 3cf4ff472704253f295816c1017e22f4 311 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 311 44.562 T 28-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWM22_RS10140 3cf4ff472704253f295816c1017e22f4 311 SMART SM01131 183 309 1.3E-57 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWM22_RS10140 3cf4ff472704253f295816c1017e22f4 311 Pfam PF01368 DHH family 3 147 1.1E-23 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWM22_RS10140 3cf4ff472704253f295816c1017e22f4 311 Pfam PF02833 DHHA2 domain 186 308 9.2E-17 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWM22_RS10140 3cf4ff472704253f295816c1017e22f4 311 Gene3D G3DSA:3.90.1640.10 1 190 1.6E-59 T 28-03-2018 CWM22_RS12975 e604e823548edcad60e03afc9901e056 112 Gene3D G3DSA:2.30.30.110 1 110 4.3E-9 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWM22_RS12975 e604e823548edcad60e03afc9901e056 112 SUPERFAMILY SSF50118 15 108 1.77E-6 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWM22_RS10755 5226792f01ff04d4a0b4882c874bdf36 1136 Gene3D G3DSA:3.10.20.320 364 475 9.6E-5 T 28-03-2018 CWM22_RS10755 5226792f01ff04d4a0b4882c874bdf36 1136 Gene3D G3DSA:3.10.20.320 266 363 7.7E-9 T 28-03-2018 CWM22_RS10755 5226792f01ff04d4a0b4882c874bdf36 1136 Gene3D G3DSA:2.60.40.10 476 549 0.072 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS10755 5226792f01ff04d4a0b4882c874bdf36 1136 Gene3D G3DSA:2.60.40.10 150 248 0.27 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS10755 5226792f01ff04d4a0b4882c874bdf36 1136 Gene3D G3DSA:2.60.40.680 591 930 0.1 T 28-03-2018 CWM22_RS12355 2e029ddfa544088d2db962cbb5b3f0ad 702 TIGRFAM TIGR01654 bact_immun_7tm: bacteriocin-associated integral membrane protein 9 699 4.1E-96 T 28-03-2018 IPR006541 Bacteriocin-associated integral membrane protein CWM22_RS11660 3f9babbf944b125109cdb36c8af001ca 132 SUPERFAMILY SSF69065 6 130 3.66E-43 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWM22_RS11660 3f9babbf944b125109cdb36c8af001ca 132 Pfam PF00636 Ribonuclease III domain 15 112 3.9E-13 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWM22_RS11660 3f9babbf944b125109cdb36c8af001ca 132 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 4 130 28.699 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CWM22_RS11660 3f9babbf944b125109cdb36c8af001ca 132 PIRSF PIRSF005520 1 132 1.9E-51 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CWM22_RS11660 3f9babbf944b125109cdb36c8af001ca 132 Gene3D G3DSA:1.10.1520.10 4 132 1.1E-19 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWM22_RS06340 c465ca78d01055df56fd7e5227fd8a91 776 Gene3D G3DSA:3.40.50.300 229 743 1.1E-13 T 28-03-2018 CWM22_RS06340 c465ca78d01055df56fd7e5227fd8a91 776 SUPERFAMILY SSF52540 398 758 1.1E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04155 ae8384b2cb0e9dbf83dba79dd368219f 557 Pfam PF07902 gp58-like protein 191 475 5.1E-24 T 28-03-2018 IPR012892 Gp58-like CWM22_RS04155 ae8384b2cb0e9dbf83dba79dd368219f 557 SUPERFAMILY SSF49785 74 126 2.41E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS04155 ae8384b2cb0e9dbf83dba79dd368219f 557 Gene3D G3DSA:2.60.120.260 63 163 1.4E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like CWM22_RS11800 84f0ae11bb6fc1e3636ddea602bc6223 197 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 195 40.599 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CWM22_RS11800 84f0ae11bb6fc1e3636ddea602bc6223 197 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 184 4.2E-67 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CWM22_RS11800 84f0ae11bb6fc1e3636ddea602bc6223 197 Gene3D G3DSA:3.20.19.10 1 172 7.6E-43 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWM22_RS11800 84f0ae11bb6fc1e3636ddea602bc6223 197 Pfam PF00694 Aconitase C-terminal domain 1 124 1.0E-38 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CWM22_RS11800 84f0ae11bb6fc1e3636ddea602bc6223 197 SUPERFAMILY SSF52016 2 191 8.44E-56 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWM22_RS08090 92d663a72d7674b3fa821ac2420acff8 266 Gene3D G3DSA:3.40.50.1000 112 265 1.7E-10 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08090 92d663a72d7674b3fa821ac2420acff8 266 Pfam PF13419 Haloacid dehalogenase-like hydrolase 95 215 2.1E-7 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08090 92d663a72d7674b3fa821ac2420acff8 266 SUPERFAMILY SSF56784 5 237 2.71E-20 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS13345 9a489b788963c5564827584ab0df0226 285 Pfam PF13413 Helix-turn-helix domain 10 68 3.3E-15 T 28-03-2018 CWM22_RS13345 9a489b788963c5564827584ab0df0226 285 SUPERFAMILY SSF47413 4 75 1.85E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS13345 9a489b788963c5564827584ab0df0226 285 Gene3D G3DSA:1.10.260.40 1 99 2.4E-9 T 28-03-2018 CWM22_RS11435 896dd4fefeb661012902970805749d32 300 SUPERFAMILY SSF117892 65 191 4.45E-25 T 28-03-2018 IPR001107 Band 7 domain CWM22_RS11435 896dd4fefeb661012902970805749d32 300 SMART SM00244 25 185 5.0E-28 T 28-03-2018 IPR001107 Band 7 domain CWM22_RS11435 896dd4fefeb661012902970805749d32 300 Pfam PF01145 SPFH domain / Band 7 family 29 201 3.0E-29 T 28-03-2018 IPR001107 Band 7 domain CWM22_RS10430 a33c99a80500e02ae76b403794da89f3 233 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 18 227 4.9E-49 T 28-03-2018 IPR006214 Bax inhibitor 1-related CWM22_RS02740 7718e2cc8e9ee3f5d84a97d012e3f438 283 Gene3D G3DSA:3.40.50.2300 1 152 1.2E-6 T 28-03-2018 CWM22_RS12445 6948581f0405c335c935de4829f87e9c 375 Pfam PF07687 Peptidase dimerisation domain 174 269 9.4E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWM22_RS12445 6948581f0405c335c935de4829f87e9c 375 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 4 361 3.0E-87 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWM22_RS12445 6948581f0405c335c935de4829f87e9c 375 PIRSF PIRSF005962 2 375 8.0E-102 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWM22_RS12445 6948581f0405c335c935de4829f87e9c 375 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 1 373 61.821 T 28-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 CWM22_RS12445 6948581f0405c335c935de4829f87e9c 375 SUPERFAMILY SSF53187 291 366 8.2E-68 T 28-03-2018 CWM22_RS12445 6948581f0405c335c935de4829f87e9c 375 SUPERFAMILY SSF53187 3 189 8.2E-68 T 28-03-2018 CWM22_RS12445 6948581f0405c335c935de4829f87e9c 375 Gene3D G3DSA:3.40.630.10 2 272 4.1E-52 T 28-03-2018 CWM22_RS12445 6948581f0405c335c935de4829f87e9c 375 Pfam PF01546 Peptidase family M20/M25/M40 67 370 7.4E-22 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWM22_RS12445 6948581f0405c335c935de4829f87e9c 375 SUPERFAMILY SSF55031 173 289 1.44E-29 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWM22_RS05035 292d4aa66c5615a553f9589486103e60 289 Gene3D G3DSA:3.40.190.10 31 121 2.9E-9 T 28-03-2018 CWM22_RS05035 292d4aa66c5615a553f9589486103e60 289 Gene3D G3DSA:3.40.190.10 241 277 0.003 T 28-03-2018 CWM22_RS05035 292d4aa66c5615a553f9589486103e60 289 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 271 1.1E-87 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 CWM22_RS05035 292d4aa66c5615a553f9589486103e60 289 SUPERFAMILY SSF53850 33 277 8.4E-73 T 28-03-2018 CWM22_RS05035 292d4aa66c5615a553f9589486103e60 289 Gene3D G3DSA:3.40.190.10 122 228 5.0E-33 T 28-03-2018 CWM22_RS05035 292d4aa66c5615a553f9589486103e60 289 Pfam PF12849 PBP superfamily domain 31 258 7.8E-36 T 28-03-2018 IPR024370 PBP domain CWM22_RS01675 8d5bbb2f500b0034fed7a92b1a5749c6 82 Pfam PF13411 MerR HTH family regulatory protein 36 75 6.8E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS01675 8d5bbb2f500b0034fed7a92b1a5749c6 82 SUPERFAMILY SSF46955 31 80 2.01E-6 T 28-03-2018 IPR009061 Putative DNA-binding domain CWM22_RS01675 8d5bbb2f500b0034fed7a92b1a5749c6 82 Gene3D G3DSA:1.10.10.10 31 82 8.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08125 cb708b0ab19483569583eddb5d8228fa 342 SUPERFAMILY SSF53613 1 330 1.71E-61 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS08125 cb708b0ab19483569583eddb5d8228fa 342 Pfam PF00294 pfkB family carbohydrate kinase 267 309 4.2E-5 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWM22_RS08125 cb708b0ab19483569583eddb5d8228fa 342 Pfam PF00294 pfkB family carbohydrate kinase 1 195 1.5E-16 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWM22_RS08125 cb708b0ab19483569583eddb5d8228fa 342 Gene3D G3DSA:3.40.1190.20 1 342 5.7E-42 T 28-03-2018 IPR029056 Ribokinase-like CWM22_RS07155 bbdd764baa79a4244f7b1ea2f2bcf8d7 98 Pfam PF14131 Domain of unknown function (DUF4298) 7 91 1.1E-24 T 28-03-2018 IPR025384 Protein of unknown function DUF4298 CWM22_RS08265 a185ba44f3921c3352b54015d9c0efa9 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 262 4.6E-53 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08265 a185ba44f3921c3352b54015d9c0efa9 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 262 7.4E-41 T 28-03-2018 IPR000150 Cof family GO:0016787 CWM22_RS08265 a185ba44f3921c3352b54015d9c0efa9 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 234 1.4E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWM22_RS08265 a185ba44f3921c3352b54015d9c0efa9 269 SUPERFAMILY SSF56784 4 264 7.05E-56 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08265 a185ba44f3921c3352b54015d9c0efa9 269 Gene3D G3DSA:3.40.50.1000 2 269 1.8E-27 T 28-03-2018 IPR023214 HAD-like domain CWM22_RS08195 29e84aa975b4d8cd0966903869540012 347 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 130 6.8E-32 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CWM22_RS08195 29e84aa975b4d8cd0966903869540012 347 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 5 306 1.7E-71 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CWM22_RS08195 29e84aa975b4d8cd0966903869540012 347 SUPERFAMILY SSF111331 3 310 2.4E-70 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CWM22_RS08195 29e84aa975b4d8cd0966903869540012 347 SMART SM00046 6 135 1.2E-4 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CWM22_RS08195 29e84aa975b4d8cd0966903869540012 347 Gene3D G3DSA:3.40.50.10330 1 145 1.7E-29 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CWM22_RS11635 782913486a314120548c37430ba21c41 288 Gene3D G3DSA:3.30.420.40 1 108 1.6E-17 T 28-03-2018 CWM22_RS11635 782913486a314120548c37430ba21c41 288 Gene3D G3DSA:3.30.420.40 109 288 2.9E-36 T 28-03-2018 CWM22_RS11635 782913486a314120548c37430ba21c41 288 Pfam PF00480 ROK family 4 283 1.0E-40 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWM22_RS11635 782913486a314120548c37430ba21c41 288 SUPERFAMILY SSF53067 1 285 1.09E-44 T 28-03-2018 CWM22_RS00395 2f5b0125fce3c741161719c5b7c22088 307 SMART SM00530 9 65 0.0036 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS00395 2f5b0125fce3c741161719c5b7c22088 307 SUPERFAMILY SSF47413 3 68 5.32E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS00395 2f5b0125fce3c741161719c5b7c22088 307 Gene3D G3DSA:1.10.260.40 1 153 9.7E-12 T 28-03-2018 CWM22_RS10385 3098f693bdd3f04b4faf601d4793b57a 239 Gene3D G3DSA:1.10.10.580 165 231 8.9E-13 T 28-03-2018 CWM22_RS10385 3098f693bdd3f04b4faf601d4793b57a 239 Pfam PF02616 Segregation and condensation protein ScpA 18 230 2.2E-29 T 28-03-2018 IPR003768 Segregation and condensation protein A CWM22_RS10385 3098f693bdd3f04b4faf601d4793b57a 239 Hamap MF_01805 Segregation and condensation protein A [scpA]. 1 234 25.835 T 28-03-2018 IPR003768 Segregation and condensation protein A CWM22_RS11035 36ec906474a58778c40a3f94d67a471a 448 Pfam PF06889 Protein of unknown function (DUF1266) 50 173 2.6E-14 T 28-03-2018 IPR009677 Protein of unknown function DUF1266 CWM22_RS06420 7f1b2eb890d3c8eac009faeeedea6b14 57 Pfam PF14205 Cysteine-rich KTR 5 57 1.4E-32 T 28-03-2018 IPR025957 Cysteine-rich KTR CWM22_RS05700 7f1b2eb890d3c8eac009faeeedea6b14 57 Pfam PF14205 Cysteine-rich KTR 5 57 1.4E-32 T 28-03-2018 IPR025957 Cysteine-rich KTR CWM22_RS06795 3306a676b193946abcd31d3a15ea03ac 436 Gene3D G3DSA:1.10.150.130 78 194 8.2E-10 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWM22_RS06795 3306a676b193946abcd31d3a15ea03ac 436 Gene3D G3DSA:1.10.443.10 195 388 4.6E-33 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS06795 3306a676b193946abcd31d3a15ea03ac 436 Pfam PF13102 Phage integrase SAM-like domain 99 180 4.4E-7 T 28-03-2018 IPR025269 Phage integrase SAM-like domain CWM22_RS06795 3306a676b193946abcd31d3a15ea03ac 436 Pfam PF00589 Phage integrase family 210 379 1.1E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS06795 3306a676b193946abcd31d3a15ea03ac 436 SUPERFAMILY SSF56349 90 385 2.94E-51 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS08930 afbaf3105f139d3c6f5c6224c181a5d9 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 225 6.8E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS08930 afbaf3105f139d3c6f5c6224c181a5d9 232 SUPERFAMILY SSF161098 22 212 2.75E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS08930 afbaf3105f139d3c6f5c6224c181a5d9 232 Gene3D G3DSA:1.10.3720.10 2 228 1.5E-47 T 28-03-2018 CWM22_RS08930 afbaf3105f139d3c6f5c6224c181a5d9 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 21 121 5.3E-24 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWM22_RS11905 453d179685dcfa2cc0cc125cf3cba378 334 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 102 120 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CWM22_RS11905 453d179685dcfa2cc0cc125cf3cba378 334 PIRSF PIRSF006621 7 333 8.0E-99 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CWM22_RS11905 453d179685dcfa2cc0cc125cf3cba378 334 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 10 327 1.0E-104 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CWM22_RS11905 453d179685dcfa2cc0cc125cf3cba378 334 SUPERFAMILY SSF51395 17 326 9.16E-83 T 28-03-2018 CWM22_RS11905 453d179685dcfa2cc0cc125cf3cba378 334 Gene3D G3DSA:1.10.1200.80 259 334 2.4E-13 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CWM22_RS11905 453d179685dcfa2cc0cc125cf3cba378 334 Gene3D G3DSA:3.20.20.70 13 255 2.8E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS11905 453d179685dcfa2cc0cc125cf3cba378 334 Pfam PF01207 Dihydrouridine synthase (Dus) 20 322 3.5E-83 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CWM22_RS11325 3403c490518c092c3a165cf3d33ac6f6 397 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 80 236 1.3E-41 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWM22_RS11325 3403c490518c092c3a165cf3d33ac6f6 397 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 81 236 5.4E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWM22_RS05220 877b14fcc5e6a369aba6eead2e8e2994 236 SUPERFAMILY SSF53448 1 222 6.98E-57 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05220 877b14fcc5e6a369aba6eead2e8e2994 236 Pfam PF04488 Glycosyltransferase sugar-binding region containing DXD motif 17 100 6.3E-13 T 28-03-2018 IPR007577 Glycosyltransferase, DXD sugar-binding motif CWM22_RS02345 6fd79b6df262f4b3d5bd376ed2bfb5aa 263 Gene3D G3DSA:3.60.10.10 1 262 1.3E-34 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWM22_RS02345 6fd79b6df262f4b3d5bd376ed2bfb5aa 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 19 254 3.6E-7 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWM22_RS02345 6fd79b6df262f4b3d5bd376ed2bfb5aa 263 SUPERFAMILY SSF56219 1 261 4.32E-36 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 Gene3D G3DSA:3.30.870.10 345 511 5.8E-32 T 28-03-2018 CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 Pfam PF13396 Phospholipase_D-nuclease N-terminal 46 86 3.7E-8 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 43 515 3.6E-101 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 Gene3D G3DSA:3.30.870.10 109 310 4.7E-33 T 28-03-2018 CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 SUPERFAMILY SSF56024 106 323 4.93E-42 T 28-03-2018 CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 Pfam PF13091 PLD-like domain 354 479 3.4E-24 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 Pfam PF13091 PLD-like domain 161 304 5.2E-13 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 SUPERFAMILY SSF56024 341 500 6.5E-37 T 28-03-2018 CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 SMART SM00155 426 453 4.3E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWM22_RS07950 930b67c9eaa128afdb17e81e36ed079d 515 SMART SM00155 244 271 7.1E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 570 1.6E-197 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 SUPERFAMILY SSF46600 183 235 1.31E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 27.436 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 372 523 5.2E-54 T 28-03-2018 IPR001162 UvrC family homology region CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 SUPERFAMILY SSF82771 15 97 5.49E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 SUPERFAMILY SSF47781 502 588 6.35E-19 T 28-03-2018 IPR010994 RuvA domain 2-like CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 Pfam PF02151 UvrB/uvrC motif 196 229 5.4E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 Gene3D G3DSA:3.40.1440.10 1 98 2.6E-24 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 Gene3D G3DSA:4.10.860.10 174 234 2.1E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 Pfam PF01541 GIY-YIG catalytic domain 17 90 1.9E-9 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 Gene3D G3DSA:1.10.150.20 522 589 1.5E-11 T 28-03-2018 CWM22_RS07360 8dfb6339a81eb4b5b31ad0b12a9ed067 589 SMART SM00465 15 95 1.3E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWM22_RS08285 381fd60690e90775c468e8935ce69d6c 346 SMART SM00418 264 338 8.7E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWM22_RS08285 381fd60690e90775c468e8935ce69d6c 346 Gene3D G3DSA:1.10.10.10 232 345 7.2E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS08285 381fd60690e90775c468e8935ce69d6c 346 SUPERFAMILY SSF46785 249 344 4.49E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05235 7a8317cf0a0ca330347b76ffc8b0d410 349 SUPERFAMILY SSF51735 4 348 4.44E-87 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS05235 7a8317cf0a0ca330347b76ffc8b0d410 349 Gene3D G3DSA:3.90.25.10 187 349 6.5E-38 T 28-03-2018 CWM22_RS05235 7a8317cf0a0ca330347b76ffc8b0d410 349 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 247 1.8E-56 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CWM22_RS05235 7a8317cf0a0ca330347b76ffc8b0d410 349 Gene3D G3DSA:3.40.50.720 1 186 4.6E-33 T 28-03-2018 CWM22_RS05235 7a8317cf0a0ca330347b76ffc8b0d410 349 PRINTS PR01713 Nucleotide sugar epimerase signature 227 242 9.4E-26 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS05235 7a8317cf0a0ca330347b76ffc8b0d410 349 PRINTS PR01713 Nucleotide sugar epimerase signature 35 51 9.4E-26 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS05235 7a8317cf0a0ca330347b76ffc8b0d410 349 PRINTS PR01713 Nucleotide sugar epimerase signature 310 327 9.4E-26 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS05235 7a8317cf0a0ca330347b76ffc8b0d410 349 PRINTS PR01713 Nucleotide sugar epimerase signature 261 276 9.4E-26 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.2E-6 T 28-03-2018 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 167 1.2E-6 T 28-03-2018 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 342 364 1.2E-5 T 28-03-2018 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.2E-5 T 28-03-2018 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.2E-5 T 28-03-2018 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 SUPERFAMILY SSF51905 1 191 7.11E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 SUPERFAMILY SSF51905 332 386 7.11E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 Gene3D G3DSA:3.50.50.60 3 391 6.4E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 SUPERFAMILY SSF160996 194 335 8.11E-33 T 28-03-2018 CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 387 3.6E-131 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CWM22_RS01165 3eac9fc61f8ab24450be269c9b5ad1d7 391 Pfam PF03486 HI0933-like protein 5 387 3.9E-137 T 28-03-2018 CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 Gene3D G3DSA:3.40.630.10 5 196 3.2E-24 T 28-03-2018 CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 TIGRFAM TIGR01886 dipeptidase: dipeptidase PepV 2 466 6.2E-215 T 28-03-2018 IPR011291 Peptidase M20A, peptidase V CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 13 461 3.3E-171 T 28-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 82 91 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 Gene3D G3DSA:3.30.70.360 285 371 1.2E-26 T 28-03-2018 CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 SUPERFAMILY SSF53187 2 188 4.0E-66 T 28-03-2018 CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 SUPERFAMILY SSF53187 383 465 4.0E-66 T 28-03-2018 CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 Gene3D G3DSA:3.30.70.360 205 284 3.8E-9 T 28-03-2018 CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 116 155 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 SUPERFAMILY SSF55031 188 368 1.68E-49 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWM22_RS04590 e7f446ecd918431f550c785d51bea494 466 Pfam PF01546 Peptidase family M20/M25/M40 86 462 5.9E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWM22_RS09790 fd322d5673addce4291d9f8f79f364ae 114 SUPERFAMILY SSF50118 4 113 2.62E-26 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWM22_RS09790 fd322d5673addce4291d9f8f79f364ae 114 Gene3D G3DSA:2.30.30.110 2 113 1.1E-21 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWM22_RS09790 fd322d5673addce4291d9f8f79f364ae 114 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 9 106 3.5E-19 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CWM22_RS04560 f56259781ff18319ae56a21d3feba041 283 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 25 265 2.0E-81 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CWM22_RS04560 f56259781ff18319ae56a21d3feba041 283 PIRSF PIRSF004793 16 277 7.4E-83 T 28-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CWM22_RS04560 f56259781ff18319ae56a21d3feba041 283 SUPERFAMILY SSF143597 52 249 2.48E-63 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWM22_RS04560 f56259781ff18319ae56a21d3feba041 283 Hamap MF_01499 Diadenylate cyclase [dacA]. 23 264 29.819 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CWM22_RS04560 f56259781ff18319ae56a21d3feba041 283 Gene3D G3DSA:3.40.1700.10 121 249 3.3E-35 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWM22_RS04560 f56259781ff18319ae56a21d3feba041 283 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 128 244 2.7E-40 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWM22_RS09125 1986c3368d51163e67f598ee585fc2f6 263 Pfam PF13930 DNA/RNA non-specific endonuclease 91 231 1.2E-29 T 28-03-2018 CWM22_RS10355 544e9e16dd994d58234501c9af4e2010 185 Pfam PF12822 ECF transporter, substrate-specific component 5 175 6.1E-24 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CWM22_RS10355 544e9e16dd994d58234501c9af4e2010 185 PIRSF PIRSF037778 1 185 3.5E-56 T 28-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CWM22_RS05165 f363311328488bb1ad4baf1ff81c04da 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 335 1.1E-144 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CWM22_RS05165 f363311328488bb1ad4baf1ff81c04da 338 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 4.7E-6 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS05165 f363311328488bb1ad4baf1ff81c04da 338 PRINTS PR01713 Nucleotide sugar epimerase signature 231 246 4.7E-6 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS05165 f363311328488bb1ad4baf1ff81c04da 338 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 4.7E-6 T 28-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CWM22_RS05165 f363311328488bb1ad4baf1ff81c04da 338 Gene3D G3DSA:3.40.50.720 1 236 2.3E-47 T 28-03-2018 CWM22_RS05165 f363311328488bb1ad4baf1ff81c04da 338 SUPERFAMILY SSF51735 1 336 2.17E-102 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS05165 f363311328488bb1ad4baf1ff81c04da 338 Gene3D G3DSA:3.90.25.10 321 337 9.4E-4 T 28-03-2018 CWM22_RS05165 f363311328488bb1ad4baf1ff81c04da 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 324 2.4E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS05165 f363311328488bb1ad4baf1ff81c04da 338 Gene3D G3DSA:3.90.25.10 237 320 8.8E-27 T 28-03-2018 CWM22_RS01190 576ef664164a54df14fdf9b416932258 94 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 83 3.1E-12 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS01190 576ef664164a54df14fdf9b416932258 94 Gene3D G3DSA:3.40.50.2300 1 92 1.4E-14 T 28-03-2018 CWM22_RS01190 576ef664164a54df14fdf9b416932258 94 SUPERFAMILY SSF52794 1 89 7.32E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS10025 51be1819757b32d186a16b57dd59996b 404 Pfam PF01098 Cell cycle protein 13 391 1.9E-84 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CWM22_RS07855 5c77a1bb56d1aa4f467b50acb064b4a5 382 Pfam PF00534 Glycosyl transferases group 1 205 329 2.4E-7 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWM22_RS07855 5c77a1bb56d1aa4f467b50acb064b4a5 382 Gene3D G3DSA:3.40.50.2000 2 201 0.0053 T 28-03-2018 CWM22_RS07855 5c77a1bb56d1aa4f467b50acb064b4a5 382 SUPERFAMILY SSF53756 5 380 4.5E-27 T 28-03-2018 CWM22_RS07855 5c77a1bb56d1aa4f467b50acb064b4a5 382 Gene3D G3DSA:3.40.50.2000 202 376 6.2E-8 T 28-03-2018 CWM22_RS07855 5c77a1bb56d1aa4f467b50acb064b4a5 382 Pfam PF09314 Domain of unknown function (DUF1972) 1 185 3.0E-96 T 28-03-2018 IPR015393 Domain of unknown function DUF1972 CWM22_RS00405 98d67b8e11966f298170e811532d28ab 299 Pfam PF13560 Helix-turn-helix domain 5 60 3.6E-7 T 28-03-2018 CWM22_RS00405 98d67b8e11966f298170e811532d28ab 299 Gene3D G3DSA:1.10.260.40 1 71 1.6E-13 T 28-03-2018 CWM22_RS00405 98d67b8e11966f298170e811532d28ab 299 SUPERFAMILY SSF47413 2 68 3.1E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS00405 98d67b8e11966f298170e811532d28ab 299 SMART SM00530 9 65 2.9E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS08905 47835743e8bc2fc0b7f7e5d3a909eeca 267 SMART SM00849 16 172 6.8E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS08905 47835743e8bc2fc0b7f7e5d3a909eeca 267 SUPERFAMILY SSF56281 12 238 3.8E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS08905 47835743e8bc2fc0b7f7e5d3a909eeca 267 Pfam PF00753 Metallo-beta-lactamase superfamily 15 221 5.9E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS08905 47835743e8bc2fc0b7f7e5d3a909eeca 267 Gene3D G3DSA:3.60.15.10 12 266 1.1E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS05145 533aaf41b200437f8d2e3fc207c4946f 249 SUPERFAMILY SSF63817 29 222 2.22E-45 T 28-03-2018 IPR023365 Sortase domain CWM22_RS05145 533aaf41b200437f8d2e3fc207c4946f 249 TIGRFAM TIGR01076 sortase_fam: sortase 96 219 2.2E-19 T 28-03-2018 IPR005754 Sortase family CWM22_RS05145 533aaf41b200437f8d2e3fc207c4946f 249 Gene3D G3DSA:2.40.260.10 41 239 6.4E-38 T 28-03-2018 IPR023365 Sortase domain CWM22_RS05145 533aaf41b200437f8d2e3fc207c4946f 249 Pfam PF04203 Sortase family 97 221 4.3E-25 T 28-03-2018 IPR005754 Sortase family CWM22_RS08440 0ae686d3f4090cf9aada240489347e8f 188 SUPERFAMILY SSF55729 10 176 6.67E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS08440 0ae686d3f4090cf9aada240489347e8f 188 Gene3D G3DSA:3.40.630.30 2 184 2.5E-26 T 28-03-2018 CWM22_RS08440 0ae686d3f4090cf9aada240489347e8f 188 Pfam PF13302 Acetyltransferase (GNAT) domain 46 152 3.2E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS11215 47dd3ac686f4e3e5e16f4ff81f518977 386 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 73 320 9.9E-71 T 28-03-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 CWM22_RS11215 47dd3ac686f4e3e5e16f4ff81f518977 386 Gene3D G3DSA:2.160.20.20 10 308 1.5E-4 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like CWM22_RS11340 f62f53cba0f8220d330bda717d60d3fa 554 Gene3D G3DSA:3.30.1180.10 475 545 0.0011 T 28-03-2018 CWM22_RS11340 f62f53cba0f8220d330bda717d60d3fa 554 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 9 554 2.3E-217 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV CWM22_RS11340 f62f53cba0f8220d330bda717d60d3fa 554 SUPERFAMILY SSF101473 3 200 4.32E-48 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWM22_RS11340 f62f53cba0f8220d330bda717d60d3fa 554 SMART SM01120 34 199 5.4E-71 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWM22_RS11340 f62f53cba0f8220d330bda717d60d3fa 554 Pfam PF02734 DAK2 domain 34 198 1.6E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWM22_RS11340 f62f53cba0f8220d330bda717d60d3fa 554 SMART SM01121 240 554 9.5E-200 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CWM22_RS11340 f62f53cba0f8220d330bda717d60d3fa 554 Pfam PF13684 Dihydroxyacetone kinase family 240 554 7.6E-130 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CWM22_RS03030 44cc87bbedf92f3c7a7c4a3d417e5ee2 465 Gene3D G3DSA:3.20.20.370 248 452 1.5E-60 T 28-03-2018 CWM22_RS03030 44cc87bbedf92f3c7a7c4a3d417e5ee2 465 SUPERFAMILY SSF144015 31 258 9.42E-72 T 28-03-2018 CWM22_RS03030 44cc87bbedf92f3c7a7c4a3d417e5ee2 465 Pfam PF01522 Polysaccharide deacetylase 265 376 1.0E-35 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWM22_RS03030 44cc87bbedf92f3c7a7c4a3d417e5ee2 465 SUPERFAMILY SSF88713 266 451 4.82E-65 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWM22_RS10735 289995135d5537c394e4493a7486efef 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 60 228 6.5E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS10735 289995135d5537c394e4493a7486efef 230 Gene3D G3DSA:1.10.3720.10 20 230 4.0E-21 T 28-03-2018 CWM22_RS10735 289995135d5537c394e4493a7486efef 230 SUPERFAMILY SSF161098 22 214 3.14E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS03185 60a05c36759cab5bd7604bcd1e3f04f6 137 Pfam PF06103 Bacterial protein of unknown function (DUF948) 5 92 4.1E-25 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 CWM22_RS05245 6219e4013e941d070fbc0da11735dcc9 274 Pfam PF00535 Glycosyl transferase family 2 7 170 1.5E-21 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS05245 6219e4013e941d070fbc0da11735dcc9 274 SUPERFAMILY SSF53448 5 234 3.88E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05245 6219e4013e941d070fbc0da11735dcc9 274 Gene3D G3DSA:3.90.550.10 2 258 7.8E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS10695 c3067e4c0533176c979846c26dcef35c 445 Pfam PF01554 MatE 241 402 3.0E-18 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS10695 c3067e4c0533176c979846c26dcef35c 445 Pfam PF01554 MatE 19 179 3.4E-29 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS10695 c3067e4c0533176c979846c26dcef35c 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 406 5.3E-58 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS10695 c3067e4c0533176c979846c26dcef35c 445 PIRSF PIRSF006603 1 445 3.4E-88 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS08935 ce0678f5b7f2fac289840ac04c8e4e7c 219 Gene3D G3DSA:1.10.3720.10 5 217 4.9E-39 T 28-03-2018 CWM22_RS08935 ce0678f5b7f2fac289840ac04c8e4e7c 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 105 1.2E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWM22_RS08935 ce0678f5b7f2fac289840ac04c8e4e7c 219 SUPERFAMILY SSF161098 15 199 2.09E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS08935 ce0678f5b7f2fac289840ac04c8e4e7c 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 213 4.2E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS05675 fc0ea5c550b4cbe826ad3e325dc83c7e 90 SUPERFAMILY SSF81710 3 90 4.45E-46 T 28-03-2018 IPR015090 Bacterial epsilon antitoxin GO:0009636|GO:0015643|GO:0031342 CWM22_RS05675 fc0ea5c550b4cbe826ad3e325dc83c7e 90 Gene3D G3DSA:1.10.8.130 4 87 1.5E-33 T 28-03-2018 IPR035569 Antitoxin epsilon/PezA domain CWM22_RS05675 fc0ea5c550b4cbe826ad3e325dc83c7e 90 ProDom PD063605 PLASMID EPSILON ANTITOXIN 3D-STRUCTURE ANTIDOTE DIRECT SYSTEM SEQUENCING KILLING POSTSEGREGATIONAL 10 90 1.0E-30 T 28-03-2018 IPR015090 Bacterial epsilon antitoxin GO:0009636|GO:0015643|GO:0031342 CWM22_RS05675 fc0ea5c550b4cbe826ad3e325dc83c7e 90 Pfam PF08998 Bacterial epsilon antitoxin 2 90 3.3E-56 T 28-03-2018 IPR015090 Bacterial epsilon antitoxin GO:0009636|GO:0015643|GO:0031342 CWM22_RS05550 fc0ea5c550b4cbe826ad3e325dc83c7e 90 SUPERFAMILY SSF81710 3 90 4.45E-46 T 28-03-2018 IPR015090 Bacterial epsilon antitoxin GO:0009636|GO:0015643|GO:0031342 CWM22_RS05550 fc0ea5c550b4cbe826ad3e325dc83c7e 90 Gene3D G3DSA:1.10.8.130 4 87 1.5E-33 T 28-03-2018 IPR035569 Antitoxin epsilon/PezA domain CWM22_RS05550 fc0ea5c550b4cbe826ad3e325dc83c7e 90 ProDom PD063605 PLASMID EPSILON ANTITOXIN 3D-STRUCTURE ANTIDOTE DIRECT SYSTEM SEQUENCING KILLING POSTSEGREGATIONAL 10 90 1.0E-30 T 28-03-2018 IPR015090 Bacterial epsilon antitoxin GO:0009636|GO:0015643|GO:0031342 CWM22_RS05550 fc0ea5c550b4cbe826ad3e325dc83c7e 90 Pfam PF08998 Bacterial epsilon antitoxin 2 90 3.3E-56 T 28-03-2018 IPR015090 Bacterial epsilon antitoxin GO:0009636|GO:0015643|GO:0031342 CWM22_RS08715 db438ac1d43190c540b699525daf16e4 410 Gene3D G3DSA:3.40.190.10 154 355 2.1E-41 T 28-03-2018 CWM22_RS08715 db438ac1d43190c540b699525daf16e4 410 Gene3D G3DSA:3.40.190.10 32 153 1.6E-7 T 28-03-2018 CWM22_RS08715 db438ac1d43190c540b699525daf16e4 410 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 135 152 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 CWM22_RS08715 db438ac1d43190c540b699525daf16e4 410 Pfam PF13416 Bacterial extracellular solute-binding protein 48 356 7.6E-40 T 28-03-2018 CWM22_RS08715 db438ac1d43190c540b699525daf16e4 410 SUPERFAMILY SSF53850 21 376 9.97E-66 T 28-03-2018 CWM22_RS06110 aba1c5aa978a52beba3e20104977b6d3 809 Pfam PF12846 AAA-like domain 460 732 4.9E-9 T 28-03-2018 CWM22_RS06110 aba1c5aa978a52beba3e20104977b6d3 809 Gene3D G3DSA:3.40.50.300 462 773 9.3E-13 T 28-03-2018 CWM22_RS06110 aba1c5aa978a52beba3e20104977b6d3 809 SUPERFAMILY SSF52540 422 790 4.7E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS07810 dccd7e11bde0ed5ad4798faf2eb811dd 686 Pfam PF05045 Rhamnan synthesis protein F 102 336 1.8E-56 T 28-03-2018 IPR007739 Rhamnan synthesis F CWM22_RS07810 dccd7e11bde0ed5ad4798faf2eb811dd 686 SUPERFAMILY SSF53756 363 681 1.88E-25 T 28-03-2018 CWM22_RS07810 dccd7e11bde0ed5ad4798faf2eb811dd 686 Gene3D G3DSA:3.40.50.2000 501 671 3.0E-23 T 28-03-2018 CWM22_RS07810 dccd7e11bde0ed5ad4798faf2eb811dd 686 Pfam PF13692 Glycosyl transferases group 1 519 650 2.4E-13 T 28-03-2018 CWM22_RS10165 a18fda25f9461c949f1b188fb4c9767d 272 Gene3D G3DSA:3.60.15.10 12 264 4.5E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS10165 a18fda25f9461c949f1b188fb4c9767d 272 SUPERFAMILY SSF56281 23 246 9.0E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS10165 a18fda25f9461c949f1b188fb4c9767d 272 SMART SM00849 24 206 0.0022 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWM22_RS03380 fb2846b00ab56db5317c5f92069883dc 122 Pfam PF11877 Protein of unknown function (DUF3397) 10 117 5.7E-26 T 28-03-2018 IPR024515 Protein of unknown function DUF3397 CWM22_RS00225 192bd11383423ad0b481edf4a3de5c06 335 Pfam PF02504 Fatty acid synthesis protein 3 321 1.2E-105 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CWM22_RS00225 192bd11383423ad0b481edf4a3de5c06 335 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 335 143.481 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CWM22_RS00225 192bd11383423ad0b481edf4a3de5c06 335 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 3 330 4.1E-114 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CWM22_RS00225 192bd11383423ad0b481edf4a3de5c06 335 Gene3D G3DSA:3.40.718.10 1 331 1.4E-98 T 28-03-2018 CWM22_RS00225 192bd11383423ad0b481edf4a3de5c06 335 SUPERFAMILY SSF53659 2 325 4.52E-101 T 28-03-2018 CWM22_RS00225 192bd11383423ad0b481edf4a3de5c06 335 PIRSF PIRSF002465 1 335 9.6E-125 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CWM22_RS02950 946cfe60644ddc6ec5e354345e32e0cb 290 Gene3D G3DSA:1.10.600.10 1 287 1.5E-69 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWM22_RS02950 946cfe60644ddc6ec5e354345e32e0cb 290 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 206 218 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWM22_RS02950 946cfe60644ddc6ec5e354345e32e0cb 290 Pfam PF00348 Polyprenyl synthetase 25 250 1.5E-48 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CWM22_RS02950 946cfe60644ddc6ec5e354345e32e0cb 290 SUPERFAMILY SSF48576 9 270 1.73E-73 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWM22_RS02950 946cfe60644ddc6ec5e354345e32e0cb 290 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 92 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWM22_RS03415 7c62845ecc069a332b2d1ba14dc59ed2 546 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 381 526 2.3E-22 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CWM22_RS03415 7c62845ecc069a332b2d1ba14dc59ed2 546 Pfam PF01943 Polysaccharide biosynthesis protein 17 325 4.8E-32 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CWM22_RS03415 7c62845ecc069a332b2d1ba14dc59ed2 546 SUPERFAMILY SSF81665 104 229 4.71E-5 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS03415 7c62845ecc069a332b2d1ba14dc59ed2 546 SUPERFAMILY SSF81665 336 435 4.71E-5 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWM22_RS03415 7c62845ecc069a332b2d1ba14dc59ed2 546 PIRSF PIRSF038958 11 543 1.7E-70 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CWM22_RS01870 220c2a8fae67ef399934c97dd61debe0 107 Gene3D G3DSA:1.10.10.10 3 99 9.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01870 220c2a8fae67ef399934c97dd61debe0 107 SUPERFAMILY SSF46785 11 99 2.15E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01870 220c2a8fae67ef399934c97dd61debe0 107 Pfam PF03551 Transcriptional regulator PadR-like family 19 86 2.9E-15 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWM22_RS10820 e2bfd2e1a3df60fbe6972fefa535f8f9 268 Pfam PF03609 PTS system sorbose-specific iic component 6 241 6.3E-70 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 CWM22_RS08735 88d055dbae509e8d719b772e53ff12e6 363 PIRSF PIRSF001434 1 363 3.3E-116 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWM22_RS08735 88d055dbae509e8d719b772e53ff12e6 363 SUPERFAMILY SSF53383 7 362 9.87E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS08735 88d055dbae509e8d719b772e53ff12e6 363 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 362 6.7E-121 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWM22_RS08735 88d055dbae509e8d719b772e53ff12e6 363 Gene3D G3DSA:3.40.640.10 2 245 1.5E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS08735 88d055dbae509e8d719b772e53ff12e6 363 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWM22_RS08735 88d055dbae509e8d719b772e53ff12e6 363 Gene3D G3DSA:3.90.1150.10 247 277 8.2E-6 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS08735 88d055dbae509e8d719b772e53ff12e6 363 Gene3D G3DSA:3.90.1150.10 278 363 2.0E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS05125 006eb4afa4e128498b2356bfd6aecef8 353 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 333 4.0E-37 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWM22_RS05125 006eb4afa4e128498b2356bfd6aecef8 353 Gene3D G3DSA:1.10.3470.10 51 352 3.4E-39 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS08110 e4754897a455a73c6cdc889a5981163c 206 SUPERFAMILY SSF51569 2 203 4.4E-60 T 28-03-2018 CWM22_RS08110 e4754897a455a73c6cdc889a5981163c 206 Gene3D G3DSA:3.20.20.70 1 205 1.5E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS08110 e4754897a455a73c6cdc889a5981163c 206 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 3 202 6.8E-54 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CWM22_RS08110 e4754897a455a73c6cdc889a5981163c 206 Pfam PF01081 KDPG and KHG aldolase 4 194 1.1E-41 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CWM22_RS01285 d3cc1869953c1ffc2e31430ee8d4b949 139 Pfam PF02082 Transcriptional regulator 2 82 2.1E-23 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWM22_RS01285 d3cc1869953c1ffc2e31430ee8d4b949 139 SUPERFAMILY SSF46785 5 136 5.93E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01285 d3cc1869953c1ffc2e31430ee8d4b949 139 Gene3D G3DSA:1.10.10.10 1 139 1.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12405 2d1096e896564a072a18f62038df625e 264 Pfam PF01226 Formate/nitrite transporter 8 253 5.6E-45 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CWM22_RS12405 2d1096e896564a072a18f62038df625e 264 Gene3D G3DSA:1.20.1080.10 2 264 1.1E-51 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWM22_RS02935 41e667dc5bc1930e40199be3aa1fb0f3 302 Gene3D G3DSA:3.40.390.10 56 275 1.9E-4 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CWM22_RS02935 41e667dc5bc1930e40199be3aa1fb0f3 302 Pfam PF04228 Putative neutral zinc metallopeptidase 1 297 4.8E-109 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CWM22_RS02935 41e667dc5bc1930e40199be3aa1fb0f3 302 SUPERFAMILY SSF55486 93 264 1.66E-6 T 28-03-2018 CWM22_RS03180 a81a157bdf36b270189994ef0539fee9 267 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 9 260 17.689 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWM22_RS03180 a81a157bdf36b270189994ef0539fee9 267 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 7 255 8.8E-68 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWM22_RS03180 a81a157bdf36b270189994ef0539fee9 267 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWM22_RS03180 a81a157bdf36b270189994ef0539fee9 267 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 254 3.6E-75 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWM22_RS09650 71a56cc93a28f1e97b6f34fe8a991860 152 Pfam PF14265 Domain of unknown function (DUF4355) 8 119 4.3E-6 T 28-03-2018 IPR025580 Protein of unknown function DUF4355 CWM22_RS09650 71a56cc93a28f1e97b6f34fe8a991860 152 Gene3D G3DSA:1.10.287.540 8 41 3.4E-4 T 28-03-2018 CWM22_RS09650 71a56cc93a28f1e97b6f34fe8a991860 152 Gene3D G3DSA:1.20.5.10 42 81 2.1E-7 T 28-03-2018 CWM22_RS11490 ba3c53deb5053bdc43906abe957f4bb1 149 Gene3D G3DSA:2.30.110.10 1 149 8.9E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWM22_RS11490 ba3c53deb5053bdc43906abe957f4bb1 149 SUPERFAMILY SSF50475 3 133 2.24E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWM22_RS11490 ba3c53deb5053bdc43906abe957f4bb1 149 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 88 2.5E-11 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CWM22_RS10330 a777a24dbe8fd209a818702ef8580401 70 SUPERFAMILY SSF69047 1 63 1.31E-12 T 28-03-2018 IPR008462 CsbD-like domain CWM22_RS10330 a777a24dbe8fd209a818702ef8580401 70 Gene3D G3DSA:1.10.1470.10 1 69 2.5E-16 T 28-03-2018 IPR008462 CsbD-like domain CWM22_RS10330 a777a24dbe8fd209a818702ef8580401 70 Pfam PF05532 CsbD-like 4 55 2.9E-14 T 28-03-2018 IPR008462 CsbD-like domain CWM22_RS09640 106e3eb8535b6211a739ff15903998a6 74 Gene3D G3DSA:1.10.720.40 33 72 8.0E-9 T 28-03-2018 IPR011015 LEM/LEM-like domain CWM22_RS08395 63821c16cda900e9829453e4a14849be 150 Gene3D G3DSA:3.40.140.10 2 141 1.3E-23 T 28-03-2018 CWM22_RS08395 63821c16cda900e9829453e4a14849be 150 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 31 111 2.1E-5 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWM22_RS08395 63821c16cda900e9829453e4a14849be 150 SUPERFAMILY SSF53927 7 142 4.52E-27 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWM22_RS07435 0602bb3cfd4db4b719dba86f17fe8bb7 130 SUPERFAMILY SSF53474 3 125 1.13E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS07435 0602bb3cfd4db4b719dba86f17fe8bb7 130 Gene3D G3DSA:3.40.50.1820 2 126 1.0E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS11345 a8ca5db0330078719723f510e69e020d 121 Pfam PF03780 Asp23 family, cell envelope-related function 9 117 6.2E-33 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CWM22_RS04070 ca9f07e09f2da27372a8246ce9416a39 489 TIGRFAM TIGR01538 portal_SPP1: phage portal protein, SPP1 family 19 432 2.3E-85 T 28-03-2018 IPR006428 Portal protein, SPP1-type CWM22_RS04070 ca9f07e09f2da27372a8246ce9416a39 489 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 26 437 1.2E-90 T 28-03-2018 IPR021145 Portal protein CWM22_RS12850 72b1351bba0e55ecbd19b7913e3f1d71 312 Pfam PF12642 Conjugative transposon protein TcpC 85 299 5.6E-24 T 28-03-2018 IPR024735 Conjugative transposon protein TcpC CWM22_RS11625 a5322de47bc948ba1df673b63672b1a6 309 SUPERFAMILY SSF161098 62 293 1.23E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS11625 a5322de47bc948ba1df673b63672b1a6 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 302 1.2E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS11625 a5322de47bc948ba1df673b63672b1a6 309 Gene3D G3DSA:1.10.3720.10 13 308 6.0E-45 T 28-03-2018 CWM22_RS03120 f80e2e57b53043cb036282dffd86f098 286 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 126 279 5.2E-52 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWM22_RS03120 f80e2e57b53043cb036282dffd86f098 286 SUPERFAMILY SSF55920 1 101 2.0E-68 T 28-03-2018 IPR000994 Peptidase M24 CWM22_RS03120 f80e2e57b53043cb036282dffd86f098 286 SUPERFAMILY SSF55920 129 279 2.0E-68 T 28-03-2018 IPR000994 Peptidase M24 CWM22_RS03120 f80e2e57b53043cb036282dffd86f098 286 Gene3D G3DSA:3.90.230.10 1 281 2.1E-70 T 28-03-2018 CWM22_RS03120 f80e2e57b53043cb036282dffd86f098 286 Hamap MF_01974 Methionine aminopeptidase [map]. 2 280 35.977 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWM22_RS03120 f80e2e57b53043cb036282dffd86f098 286 Pfam PF00557 Metallopeptidase family M24 129 271 3.5E-29 T 28-03-2018 IPR000994 Peptidase M24 CWM22_RS03120 f80e2e57b53043cb036282dffd86f098 286 Pfam PF00557 Metallopeptidase family M24 12 100 5.9E-10 T 28-03-2018 IPR000994 Peptidase M24 CWM22_RS00935 65942fc4f977bccd58f8d5d102d05edc 183 Pfam PF07155 ECF-type riboflavin transporter, S component 8 172 1.6E-11 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CWM22_RS00935 65942fc4f977bccd58f8d5d102d05edc 183 TIGRFAM TIGR04518 ECF_S_folT_fam: ECF transporter S component, folate family 7 171 8.6E-41 T 28-03-2018 IPR030949 ECF transporter S component, folate family CWM22_RS04240 25ede36340ff6d55db769680edfacdeb 409 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 346 370 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CWM22_RS04240 25ede36340ff6d55db769680edfacdeb 409 Pfam PF01098 Cell cycle protein 23 388 2.3E-80 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CWM22_RS06265 c65c294eacbd44b3ee54f7500a9212e6 82 Pfam PF11372 Domain of unknown function (DUF3173) 2 73 2.2E-24 T 28-03-2018 IPR021512 Protein of unknown function DUF3173 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 SUPERFAMILY SSF54686 1 135 6.41E-54 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 Gene3D G3DSA:3.90.1170.10 3 137 5.3E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 5.3E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.828 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 4.6E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 4.6E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 4.6E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 4.6E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00530 5ccb3977049d4ef07300b9f74fcd611d 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 8.4E-57 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS05270 75f89c5746b3abebf2da619182ab1c5a 333 Gene3D G3DSA:3.90.550.10 2 313 6.0E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05270 75f89c5746b3abebf2da619182ab1c5a 333 Pfam PF00535 Glycosyl transferase family 2 8 129 1.2E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS05270 75f89c5746b3abebf2da619182ab1c5a 333 SUPERFAMILY SSF53448 5 234 2.81E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS09680 deb27a8219398f1bd5ea0713106e7075 53 Gene3D G3DSA:1.10.1220.10 4 53 2.2E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWM22_RS01035 536b75a4890d3c64ea7afac3e7b5d626 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 231 301 9.9E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS01035 536b75a4890d3c64ea7afac3e7b5d626 373 Pfam PF01548 Transposase 9 155 1.3E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS00430 de5bb6c37ff7147a99cb441d20563849 121 SMART SM00530 7 62 7.6E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS00430 de5bb6c37ff7147a99cb441d20563849 121 Gene3D G3DSA:1.10.260.40 1 83 1.6E-15 T 28-03-2018 CWM22_RS00430 de5bb6c37ff7147a99cb441d20563849 121 Pfam PF01381 Helix-turn-helix 18 62 8.2E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS00430 de5bb6c37ff7147a99cb441d20563849 121 SUPERFAMILY SSF47413 1 66 2.82E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS07135 4704d142e1f124835f285f14dc6b2b3f 589 Pfam PF00005 ABC transporter 366 514 4.7E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS07135 4704d142e1f124835f285f14dc6b2b3f 589 SUPERFAMILY SSF90123 9 332 2.49E-76 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS07135 4704d142e1f124835f285f14dc6b2b3f 589 Gene3D G3DSA:3.40.50.300 335 589 2.4E-77 T 28-03-2018 CWM22_RS07135 4704d142e1f124835f285f14dc6b2b3f 589 Gene3D G3DSA:1.20.1560.10 2 334 1.8E-73 T 28-03-2018 CWM22_RS07135 4704d142e1f124835f285f14dc6b2b3f 589 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS07135 4704d142e1f124835f285f14dc6b2b3f 589 Pfam PF00664 ABC transporter transmembrane region 21 304 1.4E-50 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWM22_RS07135 4704d142e1f124835f285f14dc6b2b3f 589 SMART SM00382 374 546 2.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS07135 4704d142e1f124835f285f14dc6b2b3f 589 SUPERFAMILY SSF52540 343 585 3.55E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS01055 5d012039aa2fc4c70564d20b6d2c4f54 171 Pfam PF06081 Aromatic acid exporter family member 1 13 158 5.6E-16 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CWM22_RS03540 966bafc116aecd523564c572f8315797 228 Pfam PF13614 AAA domain 36 194 1.8E-13 T 28-03-2018 IPR025669 AAA domain CWM22_RS03540 966bafc116aecd523564c572f8315797 228 SUPERFAMILY SSF52540 36 216 2.59E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03540 966bafc116aecd523564c572f8315797 228 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 19 222 3.5E-89 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CWM22_RS03540 966bafc116aecd523564c572f8315797 228 Gene3D G3DSA:3.40.50.300 3 222 3.7E-39 T 28-03-2018 CWM22_RS02835 eb110c735897ae657ccf79a1651724fb 263 Gene3D G3DSA:3.10.290.10 183 237 1.0E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS02835 eb110c735897ae657ccf79a1651724fb 263 SMART SM00363 186 245 2.8E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS02835 eb110c735897ae657ccf79a1651724fb 263 Pfam PF01479 S4 domain 186 231 3.2E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWM22_RS02835 eb110c735897ae657ccf79a1651724fb 263 SUPERFAMILY SSF55174 183 254 1.02E-25 T 28-03-2018 CWM22_RS02835 eb110c735897ae657ccf79a1651724fb 263 SUPERFAMILY SSF55174 40 130 1.02E-25 T 28-03-2018 CWM22_RS13380 7b906913034ec55339cf2655b60555a6 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 1.2E-15 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CWM22_RS13380 7b906913034ec55339cf2655b60555a6 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 210 2.4E-60 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWM22_RS13380 7b906913034ec55339cf2655b60555a6 290 PIRSF PIRSF006483 1 277 8.2E-76 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWM22_RS09245 442b4389049c363c04d87b67dede41af 145 Pfam PF13380 CoA binding domain 21 138 1.5E-34 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CWM22_RS09245 442b4389049c363c04d87b67dede41af 145 SUPERFAMILY SSF51735 12 139 7.0E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS09245 442b4389049c363c04d87b67dede41af 145 SMART SM00881 17 111 6.3E-21 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CWM22_RS09245 442b4389049c363c04d87b67dede41af 145 Gene3D G3DSA:3.40.50.720 17 143 6.2E-30 T 28-03-2018 CWM22_RS00210 a7f754618a5ed8c24415344515e6b4c2 458 Pfam PF13751 Transposase DDE domain 322 440 3.4E-21 T 28-03-2018 IPR025668 Transposase DDE domain CWM22_RS00210 a7f754618a5ed8c24415344515e6b4c2 458 Pfam PF05598 Transposase domain (DUF772) 54 129 3.0E-20 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWM22_RS01965 b1f9910fbc53bdef3da77df1d09eb000 204 Gene3D G3DSA:2.60.120.200 5 192 2.4E-39 T 28-03-2018 CWM22_RS01965 b1f9910fbc53bdef3da77df1d09eb000 204 PIRSF PIRSF022704 1 199 2.1E-61 T 28-03-2018 IPR015987 Uncharacterised conserved protein UCP022704 CWM22_RS01965 b1f9910fbc53bdef3da77df1d09eb000 204 Pfam PF07081 Protein of unknown function (DUF1349) 11 190 5.7E-68 T 28-03-2018 IPR009784 Protein of unknown function DUF1349 CWM22_RS01965 b1f9910fbc53bdef3da77df1d09eb000 204 SUPERFAMILY SSF49899 9 190 1.9E-40 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CWM22_RS07790 09fe225b301bc4f83c31ec1d09604c07 262 SUPERFAMILY SSF53448 7 225 3.56E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07790 09fe225b301bc4f83c31ec1d09604c07 262 Gene3D G3DSA:3.90.550.10 5 232 1.8E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07790 09fe225b301bc4f83c31ec1d09604c07 262 Pfam PF00535 Glycosyl transferase family 2 7 105 3.1E-11 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS05265 42135d9874a84366ba3ffadd36faa6fe 332 Gene3D G3DSA:3.90.550.10 1 311 2.3E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05265 42135d9874a84366ba3ffadd36faa6fe 332 Pfam PF00535 Glycosyl transferase family 2 7 145 2.3E-30 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS05265 42135d9874a84366ba3ffadd36faa6fe 332 SUPERFAMILY SSF53448 4 233 5.13E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05095 bd9a137721cf8a0aabf14aef035ec175 196 Pfam PF05175 Methyltransferase small domain 28 191 8.7E-50 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CWM22_RS05095 bd9a137721cf8a0aabf14aef035ec175 196 SUPERFAMILY SSF53335 7 194 6.29E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS05095 bd9a137721cf8a0aabf14aef035ec175 196 Gene3D G3DSA:3.40.50.150 25 196 6.4E-28 T 28-03-2018 CWM22_RS10235 2edd9063504f7e8b4c415dbd65d032e5 214 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 9 88 1.5E-25 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal CWM22_RS10350 d814baa759621986c4ea6478444e6fe0 217 Pfam PF01569 PAP2 superfamily 91 207 3.8E-20 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWM22_RS10350 d814baa759621986c4ea6478444e6fe0 217 Gene3D G3DSA:1.20.144.10 48 216 7.2E-26 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWM22_RS10350 d814baa759621986c4ea6478444e6fe0 217 SMART SM00014 88 200 3.0E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWM22_RS10350 d814baa759621986c4ea6478444e6fe0 217 SUPERFAMILY SSF48317 14 217 1.83E-44 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWM22_RS04705 54ac9cbc3cb5c90356a91710acc0764d 219 Pfam PF00589 Phage integrase family 13 202 2.8E-26 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS04705 54ac9cbc3cb5c90356a91710acc0764d 219 Gene3D G3DSA:1.10.443.10 12 210 2.7E-38 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS04705 54ac9cbc3cb5c90356a91710acc0764d 219 SUPERFAMILY SSF56349 9 209 1.18E-40 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS09515 b945ae5dd9c952cee8744cd6936319f9 234 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 37 232 1.1E-81 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CWM22_RS09515 b945ae5dd9c952cee8744cd6936319f9 234 Gene3D G3DSA:3.20.20.70 1 234 1.9E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS09515 b945ae5dd9c952cee8744cd6936319f9 234 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 11 232 38.675 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CWM22_RS09515 b945ae5dd9c952cee8744cd6936319f9 234 SUPERFAMILY SSF51366 11 230 1.46E-51 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWM22_RS09655 e5a1a787660b7abfca5501928f9bbe52 470 SUPERFAMILY SSF52540 74 197 1.75E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09655 e5a1a787660b7abfca5501928f9bbe52 470 Gene3D G3DSA:3.40.50.300 10 197 4.1E-4 T 28-03-2018 CWM22_RS09655 e5a1a787660b7abfca5501928f9bbe52 470 Pfam PF03354 Phage Terminase 132 334 3.6E-6 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CWM22_RS08415 951bb1c9083be65457c197ac2dd35192 239 SUPERFAMILY SSF53335 2 224 1.27E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS08415 951bb1c9083be65457c197ac2dd35192 239 Gene3D G3DSA:3.40.50.150 19 229 2.8E-35 T 28-03-2018 CWM22_RS08415 951bb1c9083be65457c197ac2dd35192 239 Pfam PF01596 O-methyltransferase 33 227 3.8E-31 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CWM22_RS03035 48f50d7ac2b08616ffaee7431a007476 360 SMART SM00487 17 207 1.2E-40 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS03035 48f50d7ac2b08616ffaee7431a007476 360 Gene3D G3DSA:3.40.50.300 10 204 8.1E-45 T 28-03-2018 CWM22_RS03035 48f50d7ac2b08616ffaee7431a007476 360 Gene3D G3DSA:3.40.50.300 205 357 6.5E-30 T 28-03-2018 CWM22_RS03035 48f50d7ac2b08616ffaee7431a007476 360 Pfam PF00270 DEAD/DEAH box helicase 22 186 5.5E-39 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWM22_RS03035 48f50d7ac2b08616ffaee7431a007476 360 Pfam PF00271 Helicase conserved C-terminal domain 227 323 1.0E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS03035 48f50d7ac2b08616ffaee7431a007476 360 SUPERFAMILY SSF52540 67 336 3.66E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03035 48f50d7ac2b08616ffaee7431a007476 360 SMART SM00490 242 323 4.5E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS03835 4792641100bd4c5ca597619363325be1 261 SUPERFAMILY SSF52540 4 229 1.33E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03835 4792641100bd4c5ca597619363325be1 261 Gene3D G3DSA:3.40.50.300 1 236 7.2E-56 T 28-03-2018 CWM22_RS03835 4792641100bd4c5ca597619363325be1 261 Pfam PF00005 ABC transporter 20 167 7.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS03835 4792641100bd4c5ca597619363325be1 261 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS03835 4792641100bd4c5ca597619363325be1 261 SMART SM00382 28 217 1.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS05060 af01e8898e51a750556675b47f71789d 218 Gene3D G3DSA:1.20.58.220 1 112 8.5E-29 T 28-03-2018 CWM22_RS05060 af01e8898e51a750556675b47f71789d 218 SUPERFAMILY SSF109755 4 217 4.29E-64 T 28-03-2018 CWM22_RS05060 af01e8898e51a750556675b47f71789d 218 Gene3D G3DSA:1.20.58.220 116 218 3.5E-24 T 28-03-2018 CWM22_RS05060 af01e8898e51a750556675b47f71789d 218 Pfam PF01895 PhoU domain 122 207 2.5E-17 T 28-03-2018 IPR026022 PhoU domain CWM22_RS05060 af01e8898e51a750556675b47f71789d 218 Pfam PF01895 PhoU domain 19 104 1.3E-24 T 28-03-2018 IPR026022 PhoU domain CWM22_RS05060 af01e8898e51a750556675b47f71789d 218 PIRSF PIRSF003107 1 218 5.2E-62 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CWM22_RS05060 af01e8898e51a750556675b47f71789d 218 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 215 2.5E-73 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CWM22_RS08435 5c82e57f0dc479fc109ddd4706259d13 314 Pfam PF06054 Competence protein CoiA-like family 1 227 4.1E-47 T 28-03-2018 IPR010330 Competence-induced protein CoiA-like CWM22_RS08435 5c82e57f0dc479fc109ddd4706259d13 314 PIRSF PIRSF007487 1 314 2.1E-94 T 28-03-2018 IPR021176 Competence-induced protein CoiA CWM22_RS06030 36da23bc398f9bcd6fbc252850bc184b 216 Pfam PF03006 Haemolysin-III related 14 208 2.6E-29 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CWM22_RS06030 36da23bc398f9bcd6fbc252850bc184b 216 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 15 213 1.2E-58 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CWM22_RS11575 880e3036d53e737463087bcc407e8494 322 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 145 308 8.6E-46 T 28-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal CWM22_RS11575 880e3036d53e737463087bcc407e8494 322 Pfam PF06081 Aromatic acid exporter family member 1 1 141 1.8E-41 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CWM22_RS09430 65003a87b776866f7fed66f6eb223a72 401 PRINTS PR01035 Tetracycline resistance protein signature 342 365 1.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWM22_RS09430 65003a87b776866f7fed66f6eb223a72 401 PRINTS PR01035 Tetracycline resistance protein signature 139 161 1.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWM22_RS09430 65003a87b776866f7fed66f6eb223a72 401 PRINTS PR01035 Tetracycline resistance protein signature 21 37 1.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWM22_RS09430 65003a87b776866f7fed66f6eb223a72 401 PRINTS PR01035 Tetracycline resistance protein signature 51 70 1.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWM22_RS09430 65003a87b776866f7fed66f6eb223a72 401 PRINTS PR01035 Tetracycline resistance protein signature 109 130 1.2E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWM22_RS09430 65003a87b776866f7fed66f6eb223a72 401 Gene3D G3DSA:1.20.1250.20 4 191 1.4E-34 T 28-03-2018 CWM22_RS09430 65003a87b776866f7fed66f6eb223a72 401 Pfam PF07690 Major Facilitator Superfamily 16 303 1.4E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWM22_RS09430 65003a87b776866f7fed66f6eb223a72 401 Gene3D G3DSA:1.20.1250.20 199 397 1.0E-28 T 28-03-2018 CWM22_RS09430 65003a87b776866f7fed66f6eb223a72 401 SUPERFAMILY SSF103473 10 396 3.23E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWM22_RS02910 ff35d1c18e6639e43047c7550cb943e3 233 Pfam PF02517 CAAX protease self-immunity 135 222 7.2E-5 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS06715 e3513e7570b9db75456a7224524ba187 144 Gene3D G3DSA:3.40.630.30 7 139 2.4E-20 T 28-03-2018 CWM22_RS06715 e3513e7570b9db75456a7224524ba187 144 SUPERFAMILY SSF55729 33 135 2.44E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS06715 e3513e7570b9db75456a7224524ba187 144 Pfam PF00583 Acetyltransferase (GNAT) family 30 127 2.8E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS03265 54dc13358a83c7ecf4f22b63bb0b4fcf 249 SUPERFAMILY SSF158560 4 76 1.09E-8 T 28-03-2018 CWM22_RS03265 54dc13358a83c7ecf4f22b63bb0b4fcf 249 Gene3D G3DSA:1.10.1900.10 1 60 1.5E-11 T 28-03-2018 CWM22_RS05260 429da9dd3ef83d479cfcc8b846cb3afe 340 Pfam PF00535 Glycosyl transferase family 2 8 124 9.2E-29 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS05260 429da9dd3ef83d479cfcc8b846cb3afe 340 Gene3D G3DSA:3.90.550.10 2 296 2.8E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05260 429da9dd3ef83d479cfcc8b846cb3afe 340 SUPERFAMILY SSF53448 5 231 1.05E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07690 b133d02a2aa6a9ffe1e22580f74f446f 284 Gene3D G3DSA:2.60.40.810 135 252 1.1E-19 T 28-03-2018 CWM22_RS07690 b133d02a2aa6a9ffe1e22580f74f446f 284 SUPERFAMILY SSF49478 155 231 4.32E-7 T 28-03-2018 CWM22_RS07690 b133d02a2aa6a9ffe1e22580f74f446f 284 Gene3D G3DSA:2.60.40.10 48 134 0.035 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWM22_RS01120 9a297529e24687d75b99af439e910b31 87 Gene3D G3DSA:1.10.10.60 17 78 3.3E-6 T 28-03-2018 CWM22_RS06655 007f6b3eeedc776f3a431b7f21476ac6 248 SUPERFAMILY SSF53474 178 244 1.06E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS06655 007f6b3eeedc776f3a431b7f21476ac6 248 SUPERFAMILY SSF53474 3 145 1.06E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS06655 007f6b3eeedc776f3a431b7f21476ac6 248 Pfam PF00756 Putative esterase 13 240 3.7E-14 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CWM22_RS06655 007f6b3eeedc776f3a431b7f21476ac6 248 Gene3D G3DSA:3.40.50.1820 1 246 5.3E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS00550 985396da945cf003e156f1f9e1a95121 101 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS00550 985396da945cf003e156f1f9e1a95121 101 Gene3D G3DSA:2.30.30.30 1 90 1.3E-28 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWM22_RS00550 985396da945cf003e156f1f9e1a95121 101 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 99 2.0E-34 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00550 985396da945cf003e156f1f9e1a95121 101 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 94 19.924 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS00550 985396da945cf003e156f1f9e1a95121 101 SUPERFAMILY SSF50104 2 99 2.41E-30 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWM22_RS00550 985396da945cf003e156f1f9e1a95121 101 Pfam PF00467 KOW motif 5 36 2.7E-6 T 28-03-2018 IPR005824 KOW CWM22_RS00550 985396da945cf003e156f1f9e1a95121 101 SMART SM00739 2 29 1.5E-4 T 28-03-2018 IPR005824 KOW CWM22_RS00550 985396da945cf003e156f1f9e1a95121 101 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 99 5.9E-26 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11220 d3f940966fedcdb2c553542129552a5b 363 SUPERFAMILY SSF103473 9 362 4.84E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWM22_RS11220 d3f940966fedcdb2c553542129552a5b 363 Pfam PF07690 Major Facilitator Superfamily 7 246 7.5E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWM22_RS11220 d3f940966fedcdb2c553542129552a5b 363 Pfam PF07690 Major Facilitator Superfamily 256 356 1.6E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWM22_RS11220 d3f940966fedcdb2c553542129552a5b 363 Gene3D G3DSA:1.20.1250.20 2 180 3.7E-15 T 28-03-2018 CWM22_RS11220 d3f940966fedcdb2c553542129552a5b 363 Gene3D G3DSA:1.20.1250.20 254 363 2.3E-8 T 28-03-2018 CWM22_RS00020 8b1ab34d1c4ac6f71e200cb2443316ed 67 Pfam PF06107 Bacterial protein of unknown function (DUF951) 2 62 2.8E-27 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CWM22_RS00020 8b1ab34d1c4ac6f71e200cb2443316ed 67 PIRSF PIRSF037263 1 67 1.5E-32 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CWM22_RS07990 5963a24002c7a80860aa9a26da99e261 429 Pfam PF01609 Transposase DDE domain 100 351 4.1E-28 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWM22_RS07990 5963a24002c7a80860aa9a26da99e261 429 Gene3D G3DSA:3.90.350.10 112 335 2.0E-25 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWM22_RS07990 5963a24002c7a80860aa9a26da99e261 429 SUPERFAMILY SSF53098 98 391 3.34E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS13320 56d7072a59f414cbc72d224e3e7779b0 187 SMART SM00257 32 76 2.4E-14 T 28-03-2018 IPR018392 LysM domain CWM22_RS13320 56d7072a59f414cbc72d224e3e7779b0 187 Gene3D G3DSA:3.10.350.10 28 110 5.0E-16 T 28-03-2018 CWM22_RS13320 56d7072a59f414cbc72d224e3e7779b0 187 SUPERFAMILY SSF54106 32 75 6.67E-11 T 28-03-2018 IPR018392 LysM domain CWM22_RS13320 56d7072a59f414cbc72d224e3e7779b0 187 Pfam PF01476 LysM domain 33 73 2.9E-13 T 28-03-2018 IPR018392 LysM domain CWM22_RS12550 628304434293f40f7a45d82f9a0d07eb 188 Pfam PF05257 CHAP domain 77 155 5.5E-15 T 28-03-2018 IPR007921 CHAP domain CWM22_RS12550 628304434293f40f7a45d82f9a0d07eb 188 SUPERFAMILY SSF54001 73 185 3.04E-24 T 28-03-2018 CWM22_RS05985 f6ee6ce72029de994bd244fb5f8885d2 308 SUPERFAMILY SSF53448 1 241 1.41E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05985 f6ee6ce72029de994bd244fb5f8885d2 308 Gene3D G3DSA:3.90.550.10 1 213 3.2E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05985 f6ee6ce72029de994bd244fb5f8885d2 308 Pfam PF00535 Glycosyl transferase family 2 3 167 1.2E-29 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS08350 25e85235f35f12ec422434877a68b9fc 224 Pfam PF02517 CAAX protease self-immunity 122 214 7.3E-12 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS06240 0ab8b9a407d779a43f3d1ff81b7a594a 446 SUPERFAMILY SSF51445 11 340 3.47E-104 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS06240 0ab8b9a407d779a43f3d1ff81b7a594a 446 SMART SM00812 1 379 4.5E-148 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CWM22_RS06240 0ab8b9a407d779a43f3d1ff81b7a594a 446 PRINTS PR00741 Glycosyl hydrolase family 29 signature 78 94 4.5E-6 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CWM22_RS06240 0ab8b9a407d779a43f3d1ff81b7a594a 446 PRINTS PR00741 Glycosyl hydrolase family 29 signature 123 142 4.5E-6 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CWM22_RS06240 0ab8b9a407d779a43f3d1ff81b7a594a 446 Gene3D G3DSA:3.20.20.80 1 344 6.9E-106 T 28-03-2018 CWM22_RS06240 0ab8b9a407d779a43f3d1ff81b7a594a 446 PIRSF PIRSF001092 1 438 6.7E-140 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CWM22_RS06240 0ab8b9a407d779a43f3d1ff81b7a594a 446 Pfam PF01120 Alpha-L-fucosidase 4 337 1.1E-94 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CWM22_RS06240 0ab8b9a407d779a43f3d1ff81b7a594a 446 Gene3D G3DSA:2.60.40.1180 345 439 3.4E-21 T 28-03-2018 CWM22_RS04115 f9deddff5a125530aa89faac1fd39b18 170 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 8 84 6.4E-9 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CWM22_RS04115 f9deddff5a125530aa89faac1fd39b18 170 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 5 157 2.6E-11 T 28-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CWM22_RS03910 4a3b3c638bf91026fb9573df3b8d56af 115 Gene3D G3DSA:1.10.260.40 3 115 7.2E-14 T 28-03-2018 CWM22_RS03910 4a3b3c638bf91026fb9573df3b8d56af 115 SMART SM00530 7 60 1.3E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS03910 4a3b3c638bf91026fb9573df3b8d56af 115 SUPERFAMILY SSF47413 6 66 1.21E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS03910 4a3b3c638bf91026fb9573df3b8d56af 115 Pfam PF12844 Helix-turn-helix domain 6 65 3.1E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 PRINTS PR00732 Glycosyl hydrolase family 4 signature 105 118 2.4E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 PRINTS PR00732 Glycosyl hydrolase family 4 signature 148 165 2.4E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 PRINTS PR00732 Glycosyl hydrolase family 4 signature 200 212 2.4E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 PRINTS PR00732 Glycosyl hydrolase family 4 signature 84 100 2.4E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 PRINTS PR00732 Glycosyl hydrolase family 4 signature 119 139 2.4E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 PRINTS PR00732 Glycosyl hydrolase family 4 signature 13 28 2.4E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 PRINTS PR00732 Glycosyl hydrolase family 4 signature 174 185 2.4E-43 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 Gene3D G3DSA:3.90.1820.10 274 449 2.4E-45 T 28-03-2018 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 Gene3D G3DSA:3.90.1820.10 9 273 4.4E-49 T 28-03-2018 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 SUPERFAMILY SSF51735 11 175 4.57E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 148 179 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 SUPERFAMILY SSF56327 180 448 3.96E-82 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 Pfam PF02056 Family 4 glycosyl hydrolase 13 194 2.5E-58 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CWM22_RS12590 9d2db59259bd5cd187ea7b1edbe002d9 462 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 205 421 6.2E-44 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CWM22_RS05215 ffd13ce6699bd88ae74eeaf3d8d6a848 255 Gene3D G3DSA:3.90.550.10 1 251 4.2E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS05215 ffd13ce6699bd88ae74eeaf3d8d6a848 255 Pfam PF00535 Glycosyl transferase family 2 3 139 8.9E-26 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS05215 ffd13ce6699bd88ae74eeaf3d8d6a848 255 SUPERFAMILY SSF53448 3 212 8.44E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS08105 af366358997b026a3c9c4180297ef6db 466 Gene3D G3DSA:3.20.20.140 2 85 8.8E-23 T 28-03-2018 CWM22_RS08105 af366358997b026a3c9c4180297ef6db 466 Pfam PF02614 Glucuronate isomerase 2 464 1.5E-192 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 CWM22_RS08105 af366358997b026a3c9c4180297ef6db 466 Hamap MF_00675 Uronate isomerase [uxaC]. 1 466 43.73 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 CWM22_RS08105 af366358997b026a3c9c4180297ef6db 466 SUPERFAMILY SSF51556 1 464 8.5E-163 T 28-03-2018 IPR032466 Metal-dependent hydrolase CWM22_RS08105 af366358997b026a3c9c4180297ef6db 466 Gene3D G3DSA:3.20.20.140 86 465 1.1E-125 T 28-03-2018 CWM22_RS10435 7b9a1902b2e7d92e70065d40aa7997cd 160 Gene3D G3DSA:1.10.3210.10 15 158 8.9E-16 T 28-03-2018 CWM22_RS10435 7b9a1902b2e7d92e70065d40aa7997cd 160 SMART SM00471 33 149 0.0062 T 28-03-2018 IPR003607 HD/PDEase domain CWM22_RS10435 7b9a1902b2e7d92e70065d40aa7997cd 160 SUPERFAMILY SSF109604 22 155 6.02E-20 T 28-03-2018 CWM22_RS01590 edeeb4ff1629a5c49761f57afe7b1c5d 266 Pfam PF01226 Formate/nitrite transporter 13 256 2.0E-52 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CWM22_RS01590 edeeb4ff1629a5c49761f57afe7b1c5d 266 Gene3D G3DSA:1.20.1080.10 3 264 1.7E-59 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWM22_RS03655 4205cdfeee46ae993ad93bbb95f0d5f7 165 Gene3D G3DSA:3.10.450.40 109 164 2.5E-7 T 28-03-2018 CWM22_RS03655 4205cdfeee46ae993ad93bbb95f0d5f7 165 Gene3D G3DSA:3.10.450.40 41 104 2.8E-19 T 28-03-2018 CWM22_RS03655 4205cdfeee46ae993ad93bbb95f0d5f7 165 SUPERFAMILY SSF54403 47 109 5.27E-15 T 28-03-2018 CWM22_RS03655 4205cdfeee46ae993ad93bbb95f0d5f7 165 SUPERFAMILY SSF54403 109 162 1.22E-8 T 28-03-2018 CWM22_RS08570 ce8a3ffacc860caa2e9ce94d6f06b011 185 Gene3D G3DSA:3.40.630.30 1 180 2.7E-26 T 28-03-2018 CWM22_RS08570 ce8a3ffacc860caa2e9ce94d6f06b011 185 Pfam PF00583 Acetyltransferase (GNAT) family 42 144 1.5E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS08570 ce8a3ffacc860caa2e9ce94d6f06b011 185 SUPERFAMILY SSF55729 1 155 1.41E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS09990 8276461333837fba7a33d981790a2664 437 Pfam PF01966 HD domain 53 174 2.6E-11 T 28-03-2018 IPR006674 HD domain CWM22_RS09990 8276461333837fba7a33d981790a2664 437 SMART SM00471 49 181 1.2E-9 T 28-03-2018 IPR003607 HD/PDEase domain CWM22_RS09990 8276461333837fba7a33d981790a2664 437 Gene3D G3DSA:1.10.3210.10 2 307 1.5E-75 T 28-03-2018 CWM22_RS09990 8276461333837fba7a33d981790a2664 437 SUPERFAMILY SSF109604 2 419 2.79E-124 T 28-03-2018 CWM22_RS04850 1141cd4fad989967d6afc15ba0b075e0 1712 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 4 32 2.7E-5 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS04850 1141cd4fad989967d6afc15ba0b075e0 1712 Pfam PF09028 Mac 1 72 424 4.9E-206 T 28-03-2018 IPR015117 Ig protease IdeS GO:0008233 CWM22_RS04850 1141cd4fad989967d6afc15ba0b075e0 1712 Gene3D G3DSA:3.90.70.10 285 417 8.4E-34 T 28-03-2018 CWM22_RS04850 1141cd4fad989967d6afc15ba0b075e0 1712 SUPERFAMILY SSF54001 139 427 1.47E-90 T 28-03-2018 CWM22_RS06230 de8b2e065219fd8ebe88b70f5c0dd652 306 SUPERFAMILY SSF161098 15 303 6.8E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS06230 de8b2e065219fd8ebe88b70f5c0dd652 306 Gene3D G3DSA:1.10.3720.10 18 306 4.4E-34 T 28-03-2018 CWM22_RS06230 de8b2e065219fd8ebe88b70f5c0dd652 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 297 5.4E-6 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS05040 236f7c7b66e5279fd7b520c35d278c70 305 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 20 299 1.3E-90 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CWM22_RS05040 236f7c7b66e5279fd7b520c35d278c70 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 296 3.0E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS05040 236f7c7b66e5279fd7b520c35d278c70 305 SUPERFAMILY SSF161098 24 295 1.68E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS05040 236f7c7b66e5279fd7b520c35d278c70 305 Gene3D G3DSA:1.10.3720.10 12 293 2.7E-40 T 28-03-2018 CWM22_RS10880 56a6b85683bb024e756a32f6559fac80 308 SUPERFAMILY SSF56349 10 295 3.83E-51 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS10880 56a6b85683bb024e756a32f6559fac80 308 Pfam PF00589 Phage integrase family 115 288 6.3E-25 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS10880 56a6b85683bb024e756a32f6559fac80 308 Gene3D G3DSA:1.10.443.10 114 306 8.0E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS10880 56a6b85683bb024e756a32f6559fac80 308 Gene3D G3DSA:1.10.150.130 3 113 3.9E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWM22_RS08555 0901fee822c5f824fbcd811676f20ab9 117 Gene3D G3DSA:3.40.30.10 1 113 3.0E-34 T 28-03-2018 CWM22_RS08555 0901fee822c5f824fbcd811676f20ab9 117 SUPERFAMILY SSF52833 1 110 1.33E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS08555 0901fee822c5f824fbcd811676f20ab9 117 Pfam PF03960 ArsC family 38 109 3.6E-14 T 28-03-2018 IPR006660 Arsenate reductase-like CWM22_RS08555 0901fee822c5f824fbcd811676f20ab9 117 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 110 1.5E-31 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CWM22_RS12200 eea664e94e089be03ffbf5ab74c986ee 189 Pfam PF13662 Toprim domain 9 74 2.6E-5 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS12200 eea664e94e089be03ffbf5ab74c986ee 189 Gene3D G3DSA:3.40.1360.20 4 132 3.7E-17 T 28-03-2018 CWM22_RS12200 eea664e94e089be03ffbf5ab74c986ee 189 Hamap MF_01469 Ribonuclease M5 [rnmV]. 6 186 29.966 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CWM22_RS12200 eea664e94e089be03ffbf5ab74c986ee 189 SMART SM00493 8 81 0.0014 T 28-03-2018 IPR006171 TOPRIM domain CWM22_RS12200 eea664e94e089be03ffbf5ab74c986ee 189 SUPERFAMILY SSF110455 5 126 7.85E-35 T 28-03-2018 CWM22_RS12200 eea664e94e089be03ffbf5ab74c986ee 189 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 6 183 6.8E-45 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CWM22_RS12200 eea664e94e089be03ffbf5ab74c986ee 189 Pfam PF13331 Domain of unknown function (DUF4093) 99 184 3.2E-28 T 28-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CWM22_RS07430 9b4f5d60139cab1a2606130052be13eb 596 Gene3D G3DSA:1.10.1370.10 24 581 3.3E-21 T 28-03-2018 CWM22_RS07430 9b4f5d60139cab1a2606130052be13eb 596 Pfam PF01432 Peptidase family M3 205 582 4.0E-28 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CWM22_RS07430 9b4f5d60139cab1a2606130052be13eb 596 SUPERFAMILY SSF55486 4 578 6.23E-88 T 28-03-2018 CWM22_RS07430 9b4f5d60139cab1a2606130052be13eb 596 Pfam PF08439 Oligopeptidase F 115 181 2.4E-11 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CWM22_RS07430 9b4f5d60139cab1a2606130052be13eb 596 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 8 594 1.2E-157 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CWM22_RS05170 a6cf7280e87a888bdd4d67d14dbdc60c 245 Pfam PF02706 Chain length determinant protein 7 97 7.9E-16 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CWM22_RS05170 a6cf7280e87a888bdd4d67d14dbdc60c 245 Gene3D G3DSA:3.30.1890.10 39 153 9.8E-6 T 28-03-2018 CWM22_RS07745 5a85ac880dc5679ab2e379c691229ae3 833 SUPERFAMILY SSF142887 137 180 2.48E-13 T 28-03-2018 CWM22_RS07745 5a85ac880dc5679ab2e379c691229ae3 833 SUPERFAMILY SSF142887 63 111 4.97E-12 T 28-03-2018 CWM22_RS07745 5a85ac880dc5679ab2e379c691229ae3 833 Pfam PF04270 Streptococcal histidine triad protein 66 108 3.2E-4 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS07745 5a85ac880dc5679ab2e379c691229ae3 833 Pfam PF04270 Streptococcal histidine triad protein 208 248 9.1E-7 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS07745 5a85ac880dc5679ab2e379c691229ae3 833 Pfam PF04270 Streptococcal histidine triad protein 295 318 2.7 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS07745 5a85ac880dc5679ab2e379c691229ae3 833 Pfam PF04270 Streptococcal histidine triad protein 139 174 9.7E-13 T 28-03-2018 IPR006270 Streptococcal histidine triad repeat CWM22_RS07745 5a85ac880dc5679ab2e379c691229ae3 833 TIGRFAM TIGR01363 strep_his_triad: streptococcal histidine triad protein 131 175 6.4E-9 T 28-03-2018 IPR023832 Histidine triad protein CWM22_RS07745 5a85ac880dc5679ab2e379c691229ae3 833 SUPERFAMILY SSF142887 204 256 6.54E-15 T 28-03-2018 CWM22_RS12420 3401388a87ef2f3b098d3fd15683a3bf 149 Gene3D G3DSA:1.10.10.10 1 149 6.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12420 3401388a87ef2f3b098d3fd15683a3bf 149 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 99 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CWM22_RS12420 3401388a87ef2f3b098d3fd15683a3bf 149 SUPERFAMILY SSF46785 9 139 7.94E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12420 3401388a87ef2f3b098d3fd15683a3bf 149 SMART SM00347 24 126 4.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWM22_RS12420 3401388a87ef2f3b098d3fd15683a3bf 149 Pfam PF12802 MarR family 34 89 8.0E-10 T 28-03-2018 CWM22_RS11870 a913e8cdaba2376400a060b7973fe1ce 419 Gene3D G3DSA:2.30.42.10 204 287 4.8E-12 T 28-03-2018 CWM22_RS11870 a913e8cdaba2376400a060b7973fe1ce 419 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 5 418 1.3E-72 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CWM22_RS11870 a913e8cdaba2376400a060b7973fe1ce 419 Pfam PF02163 Peptidase family M50 6 405 7.4E-79 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CWM22_RS11870 a913e8cdaba2376400a060b7973fe1ce 419 SUPERFAMILY SSF50156 160 272 8.02E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWM22_RS01380 2bcbf3a9087ae8efd7f38e4fb64eaa6f 373 Pfam PF01548 Transposase 9 155 1.2E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS01380 2bcbf3a9087ae8efd7f38e4fb64eaa6f 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 231 301 4.3E-24 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS09385 16a84c1c067bdb2f19d3c05989738fc9 149 SUPERFAMILY SSF143100 4 71 2.88E-12 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like CWM22_RS09385 16a84c1c067bdb2f19d3c05989738fc9 149 Gene3D G3DSA:3.30.2390.10 3 75 2.1E-10 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like CWM22_RS09385 16a84c1c067bdb2f19d3c05989738fc9 149 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 17 116 1.1E-7 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system CWM22_RS11475 3da5cdcacf4977d615de7b51d5cf7af3 571 SUPERFAMILY SSF52016 385 564 6.36E-56 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWM22_RS11475 3da5cdcacf4977d615de7b51d5cf7af3 571 SUPERFAMILY SSF143975 11 383 4.84E-137 T 28-03-2018 CWM22_RS11475 3da5cdcacf4977d615de7b51d5cf7af3 571 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 12 561 44.735 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWM22_RS11475 3da5cdcacf4977d615de7b51d5cf7af3 571 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 24 561 3.6E-217 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWM22_RS11475 3da5cdcacf4977d615de7b51d5cf7af3 571 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 470 481 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWM22_RS11475 3da5cdcacf4977d615de7b51d5cf7af3 571 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 129 139 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWM22_RS11475 3da5cdcacf4977d615de7b51d5cf7af3 571 Pfam PF00920 Dehydratase family 41 558 1.3E-208 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWM22_RS01360 84ef50640426fce6c82f1e7d92e4d3fd 296 Gene3D G3DSA:3.30.420.10 66 295 4.7E-39 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS01360 84ef50640426fce6c82f1e7d92e4d3fd 296 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 295 36.156 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CWM22_RS01360 84ef50640426fce6c82f1e7d92e4d3fd 296 Pfam PF11858 Domain of unknown function (DUF3378) 3 75 4.8E-22 T 28-03-2018 IPR024568 Ribonuclease HIII, N-terminal CWM22_RS01360 84ef50640426fce6c82f1e7d92e4d3fd 296 Pfam PF01351 Ribonuclease HII 85 288 1.0E-54 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CWM22_RS01360 84ef50640426fce6c82f1e7d92e4d3fd 296 SUPERFAMILY SSF53098 83 294 1.47E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS01360 84ef50640426fce6c82f1e7d92e4d3fd 296 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 5 287 3.1E-54 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CWM22_RS01360 84ef50640426fce6c82f1e7d92e4d3fd 296 PIRSF PIRSF037748 1 296 3.6E-112 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CWM22_RS09065 cca512a0b7c7618e3131f026b907bc5f 290 Pfam PF00746 LPXTG cell wall anchor motif 244 279 3.3E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS09065 cca512a0b7c7618e3131f026b907bc5f 290 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 250 279 3.4E-4 T 28-03-2018 CWM22_RS08755 d4f25a58b4b852b96429a71054a6b0d7 249 SUPERFAMILY SSF53335 16 200 5.23E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS08755 d4f25a58b4b852b96429a71054a6b0d7 249 Gene3D G3DSA:3.40.50.150 24 216 2.1E-30 T 28-03-2018 CWM22_RS08755 d4f25a58b4b852b96429a71054a6b0d7 249 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 121 127 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWM22_RS08755 d4f25a58b4b852b96429a71054a6b0d7 249 Pfam PF05175 Methyltransferase small domain 21 175 4.6E-11 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CWM22_RS11840 63dcfab530940bbad9c0bf527cc6d2ad 329 TIGRFAM TIGR02362 dhaK1b: probable dihydroxyacetone kinase DhaK1b subunit 4 329 1.9E-155 T 28-03-2018 IPR012735 Dihydroxyacetone kinase DhaK, subunit 1b CWM22_RS11840 63dcfab530940bbad9c0bf527cc6d2ad 329 Pfam PF02733 Dak1 domain 18 327 4.9E-96 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWM22_RS11840 63dcfab530940bbad9c0bf527cc6d2ad 329 Gene3D G3DSA:3.30.1180.20 184 329 2.3E-40 T 28-03-2018 CWM22_RS11840 63dcfab530940bbad9c0bf527cc6d2ad 329 Gene3D G3DSA:3.40.50.10440 11 183 7.7E-58 T 28-03-2018 CWM22_RS11840 63dcfab530940bbad9c0bf527cc6d2ad 329 SUPERFAMILY SSF82549 11 329 1.83E-105 T 28-03-2018 CWM22_RS09150 5b1ca80a46e1009033808815ed17a12a 334 Gene3D G3DSA:1.20.1170.10 139 317 4.9E-4 T 28-03-2018 CWM22_RS05345 a95dee1eb025ce0fd4e53b59befcc848 188 PIRSF PIRSF012526 1 188 4.8E-69 T 28-03-2018 IPR009195 Uncharacterised protein family YjbK CWM22_RS05345 a95dee1eb025ce0fd4e53b59befcc848 188 SUPERFAMILY SSF55154 3 183 1.24E-32 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CWM22_RS05345 a95dee1eb025ce0fd4e53b59befcc848 188 Pfam PF01928 CYTH domain 5 183 1.1E-29 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CWM22_RS05345 a95dee1eb025ce0fd4e53b59befcc848 188 Gene3D G3DSA:2.40.320.10 1 185 1.4E-32 T 28-03-2018 CWM22_RS05345 a95dee1eb025ce0fd4e53b59befcc848 188 SMART SM01118 4 188 6.2E-21 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CWM22_RS04885 4a439df0629e4a54711bfa5cc805c0c7 213 SUPERFAMILY SSF161098 10 195 2.09E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS04885 4a439df0629e4a54711bfa5cc805c0c7 213 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 105 3.7E-27 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWM22_RS04885 4a439df0629e4a54711bfa5cc805c0c7 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 209 4.4E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS04885 4a439df0629e4a54711bfa5cc805c0c7 213 Gene3D G3DSA:1.10.3720.10 2 213 1.5E-43 T 28-03-2018 CWM22_RS04825 7a2400906ae2502d421a4db09a4fb297 235 Gene3D G3DSA:3.40.50.300 3 235 2.2E-50 T 28-03-2018 CWM22_RS04825 7a2400906ae2502d421a4db09a4fb297 235 SMART SM00382 32 207 7.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS04825 7a2400906ae2502d421a4db09a4fb297 235 Pfam PF00005 ABC transporter 23 158 1.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS04825 7a2400906ae2502d421a4db09a4fb297 235 SUPERFAMILY SSF52540 7 217 9.55E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS10050 5a746a3b1de5b9b358aa85ebf5b3f9f8 280 Pfam PF04018 Domain of unknown function (DUF368) 19 236 1.7E-31 T 28-03-2018 IPR007163 Protein of unknown function DUF368 CWM22_RS07485 4d63d156dc6daccb206a6a4792292fb0 387 Gene3D G3DSA:1.10.10.60 2 47 5.7E-9 T 28-03-2018 CWM22_RS07485 4d63d156dc6daccb206a6a4792292fb0 387 SUPERFAMILY SSF53098 206 356 6.83E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS07485 4d63d156dc6daccb206a6a4792292fb0 387 Gene3D G3DSA:3.30.420.10 201 360 1.3E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS07485 4d63d156dc6daccb206a6a4792292fb0 387 Pfam PF13936 Helix-turn-helix domain 2 45 5.9E-16 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CWM22_RS10185 172b0738a33464ec79dd104f8c34b29e 400 Pfam PF02371 Transposase IS116/IS110/IS902 family 267 353 8.8E-21 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS10185 172b0738a33464ec79dd104f8c34b29e 400 Pfam PF01548 Transposase 6 155 4.1E-30 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS01920 71582e7148d9ed8f6a3c3c83494fbd10 168 Pfam PF11188 Protein of unknown function (DUF2975) 56 168 1.6E-12 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 CWM22_RS12540 06023174004623896963344b79e15148 313 Pfam PF13377 Periplasmic binding protein-like domain 158 311 2.7E-27 T 28-03-2018 CWM22_RS12540 06023174004623896963344b79e15148 313 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.2E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS12540 06023174004623896963344b79e15148 313 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.2E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS12540 06023174004623896963344b79e15148 313 Gene3D G3DSA:3.40.50.2300 58 154 2.1E-10 T 28-03-2018 CWM22_RS12540 06023174004623896963344b79e15148 313 SUPERFAMILY SSF47413 1 59 9.28E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS12540 06023174004623896963344b79e15148 313 SMART SM00354 1 71 8.8E-29 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS12540 06023174004623896963344b79e15148 313 SUPERFAMILY SSF53822 71 297 1.95E-44 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWM22_RS12540 06023174004623896963344b79e15148 313 Gene3D G3DSA:1.10.260.40 2 57 3.3E-19 T 28-03-2018 CWM22_RS12540 06023174004623896963344b79e15148 313 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.9E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWM22_RS12540 06023174004623896963344b79e15148 313 Gene3D G3DSA:3.40.50.2300 155 313 5.9E-33 T 28-03-2018 CWM22_RS12540 06023174004623896963344b79e15148 313 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CWM22_RS07565 3c5153823cd41143752898a25df4535b 269 Pfam PF13367 Protease prsW family 82 253 1.9E-19 T 28-03-2018 IPR026898 Protease PrsW GO:0008233 CWM22_RS03175 ee8c5bdeccc04aa4ff2e91d32540d747 310 Gene3D G3DSA:3.40.50.300 135 307 1.2E-39 T 28-03-2018 CWM22_RS03175 ee8c5bdeccc04aa4ff2e91d32540d747 310 Pfam PF02603 HPr Serine kinase N terminus 3 127 2.0E-39 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CWM22_RS03175 ee8c5bdeccc04aa4ff2e91d32540d747 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 4 301 1.4E-108 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CWM22_RS03175 ee8c5bdeccc04aa4ff2e91d32540d747 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 2 306 40.51 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CWM22_RS03175 ee8c5bdeccc04aa4ff2e91d32540d747 310 SUPERFAMILY SSF53795 133 298 3.97E-37 T 28-03-2018 CWM22_RS03175 ee8c5bdeccc04aa4ff2e91d32540d747 310 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 1.3E-70 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CWM22_RS03175 ee8c5bdeccc04aa4ff2e91d32540d747 310 Gene3D G3DSA:3.40.1390.20 2 132 1.3E-40 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CWM22_RS03175 ee8c5bdeccc04aa4ff2e91d32540d747 310 SUPERFAMILY SSF75138 3 131 7.32E-39 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CWM22_RS12665 3bd487c010f80f02439961f54446ce68 216 Pfam PF02517 CAAX protease self-immunity 119 206 1.3E-17 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS05250 27e116afcef1722340868399db1bd01f 333 Pfam PF05704 Capsular polysaccharide synthesis protein 71 316 1.4E-54 T 28-03-2018 IPR008441 Capsular polysaccharide synthesis CWM22_RS05250 27e116afcef1722340868399db1bd01f 333 SUPERFAMILY SSF53448 76 316 2.62E-16 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS12580 080e5d5135d9d1e7907ebfc1094e36c0 369 SUPERFAMILY SSF51445 1 241 2.11E-75 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWM22_RS12580 080e5d5135d9d1e7907ebfc1094e36c0 369 Gene3D G3DSA:3.20.20.70 3 238 1.3E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS12580 080e5d5135d9d1e7907ebfc1094e36c0 369 Gene3D G3DSA:2.40.100.10 249 362 9.9E-34 T 28-03-2018 IPR029000 Cyclophilin-like domain CWM22_RS12580 080e5d5135d9d1e7907ebfc1094e36c0 369 Pfam PF05913 Bacterial protein of unknown function (DUF871) 4 360 3.0E-119 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CWM22_RS12580 080e5d5135d9d1e7907ebfc1094e36c0 369 SUPERFAMILY SSF50891 252 360 7.59E-33 T 28-03-2018 IPR029000 Cyclophilin-like domain CWM22_RS09560 2bf5e5bf54abc0018da06d3f031ca6e4 59 Gene3D G3DSA:1.10.1220.10 6 59 1.5E-9 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWM22_RS03675 e70e21b519be859bc40acc0d5ec662ad 89 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 87 4.7E-13 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CWM22_RS03675 e70e21b519be859bc40acc0d5ec662ad 89 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 87 5.2E-12 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CWM22_RS03675 e70e21b519be859bc40acc0d5ec662ad 89 SUPERFAMILY SSF143011 1 86 1.7E-23 T 28-03-2018 IPR035095 Toxin RelE-like domain CWM22_RS03675 e70e21b519be859bc40acc0d5ec662ad 89 Gene3D G3DSA:3.30.2310.20 1 88 1.7E-23 T 28-03-2018 CWM22_RS03255 a9fd7f330062cabb2fd4abe6496b20c2 105 Gene3D G3DSA:1.10.10.10 1 98 1.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03255 a9fd7f330062cabb2fd4abe6496b20c2 105 Pfam PF03551 Transcriptional regulator PadR-like family 15 86 3.6E-22 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWM22_RS03255 a9fd7f330062cabb2fd4abe6496b20c2 105 SUPERFAMILY SSF46785 5 100 9.66E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS05990 f2b5fb31c281fa7fc188d873320df984 218 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 55 64 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS05990 f2b5fb31c281fa7fc188d873320df984 218 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 3 216 38.402 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS05990 f2b5fb31c281fa7fc188d873320df984 218 Pfam PF03167 Uracil DNA glycosylase superfamily 52 204 1.5E-22 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS05990 f2b5fb31c281fa7fc188d873320df984 218 SUPERFAMILY SSF52141 3 215 2.24E-85 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS05990 f2b5fb31c281fa7fc188d873320df984 218 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 4 209 6.3E-77 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS05990 f2b5fb31c281fa7fc188d873320df984 218 SMART SM00987 47 205 1.2E-34 T 28-03-2018 CWM22_RS05990 f2b5fb31c281fa7fc188d873320df984 218 Gene3D G3DSA:3.40.470.10 2 218 2.1E-92 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS05990 f2b5fb31c281fa7fc188d873320df984 218 SMART SM00986 47 205 1.2E-34 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWM22_RS01975 99f27a53d05809c7a7b9280bfe6ff334 143 SUPERFAMILY SSF46785 3 131 1.29E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS01975 99f27a53d05809c7a7b9280bfe6ff334 143 Pfam PF02082 Transcriptional regulator 2 77 4.7E-21 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWM22_RS01975 99f27a53d05809c7a7b9280bfe6ff334 143 Gene3D G3DSA:1.10.10.10 1 143 5.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12675 e281b9c949f9cf3c0234ef6f4fe576c3 113 Gene3D G3DSA:3.30.2310.20 1 101 3.7E-5 T 28-03-2018 CWM22_RS12675 e281b9c949f9cf3c0234ef6f4fe576c3 113 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 100 1.1E-12 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CWM22_RS12775 73e025c631e77a294f0463e024df0638 299 Pfam PF14267 Domain of unknown function (DUF4357) 243 292 2.0E-14 T 28-03-2018 IPR025579 Domain of unknown function DUF4357 CWM22_RS10045 8331576c93c9b2e6030078ba2dbc1528 182 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 7 176 3.4E-45 T 28-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CWM22_RS10045 8331576c93c9b2e6030078ba2dbc1528 182 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 9 178 3.4E-54 T 28-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CWM22_RS02445 a566aadba75526ff70c54f64d899e0f6 385 Gene3D G3DSA:3.40.50.150 165 385 5.5E-30 T 28-03-2018 CWM22_RS02445 a566aadba75526ff70c54f64d899e0f6 385 SUPERFAMILY SSF53335 146 222 1.23E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02445 a566aadba75526ff70c54f64d899e0f6 385 SUPERFAMILY SSF53335 259 370 1.23E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS02445 a566aadba75526ff70c54f64d899e0f6 385 Pfam PF01170 Putative RNA methylase family UPF0020 167 371 8.8E-56 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWM22_RS02445 a566aadba75526ff70c54f64d899e0f6 385 Pfam PF02926 THUMP domain 20 158 3.2E-6 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CWM22_RS02445 a566aadba75526ff70c54f64d899e0f6 385 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 301 313 7.0E-5 T 28-03-2018 CWM22_RS02445 a566aadba75526ff70c54f64d899e0f6 385 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 212 7.0E-5 T 28-03-2018 CWM22_RS02445 a566aadba75526ff70c54f64d899e0f6 385 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 304 310 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWM22_RS02445 a566aadba75526ff70c54f64d899e0f6 385 SMART SM00981 58 159 3.6E-8 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CWM22_RS00015 e2664c82840d319733ab2adc2a966976 293 Gene3D G3DSA:3.40.50.10330 1 131 3.3E-17 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CWM22_RS00015 e2664c82840d319733ab2adc2a966976 293 Pfam PF00609 Diacylglycerol kinase accessory domain 152 275 2.6E-5 T 28-03-2018 IPR000756 Diacylglycerol kinase, accessory domain GO:0004143|GO:0007205 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817|Reactome: R-HSA-114508 CWM22_RS00015 e2664c82840d319733ab2adc2a966976 293 SUPERFAMILY SSF111331 1 290 5.89E-48 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CWM22_RS00015 e2664c82840d319733ab2adc2a966976 293 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 120 1.7E-14 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CWM22_RS12670 3b7735cb4f309434808173ddc5c25f1d 95 Pfam PF04221 RelB antitoxin 11 87 8.0E-7 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ CWM22_RS01060 43158fe8502eeae64fa73afc0e3fbbfe 123 ProSitePatterns PS00552 MerR-type HTH domain signature. 16 38 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS01060 43158fe8502eeae64fa73afc0e3fbbfe 123 SMART SM00422 13 81 1.2E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS01060 43158fe8502eeae64fa73afc0e3fbbfe 123 Pfam PF13411 MerR HTH family regulatory protein 14 76 1.3E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWM22_RS01060 43158fe8502eeae64fa73afc0e3fbbfe 123 SUPERFAMILY SSF46955 13 85 9.16E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CWM22_RS01060 43158fe8502eeae64fa73afc0e3fbbfe 123 Gene3D G3DSA:1.10.1660.10 12 107 1.8E-21 T 28-03-2018 CWM22_RS12500 206651feab5ff5741a7ed53e06ef6a34 238 SMART SM01007 10 200 5.5E-68 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWM22_RS12500 206651feab5ff5741a7ed53e06ef6a34 238 Gene3D G3DSA:3.40.225.10 5 233 6.3E-59 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWM22_RS12500 206651feab5ff5741a7ed53e06ef6a34 238 SUPERFAMILY SSF53639 5 225 3.34E-72 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWM22_RS12500 206651feab5ff5741a7ed53e06ef6a34 238 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 198 5.7E-45 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CWM22_RS11165 12b368d665a6dd12599e0880fd1a614c 109 SUPERFAMILY SSF54909 2 84 1.39E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CWM22_RS11165 12b368d665a6dd12599e0880fd1a614c 109 Gene3D G3DSA:3.30.70.100 1 103 1.2E-11 T 28-03-2018 CWM22_RS11165 12b368d665a6dd12599e0880fd1a614c 109 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.7E-8 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 PIRSF PIRSF015855 1 504 7.1E-149 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 65 84 1.4E-10 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 270 292 1.4E-10 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 293 307 1.4E-10 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 Pfam PF01555 DNA methylase 1 331 2.1E-45 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 Gene3D G3DSA:3.40.50.150 1 338 4.6E-51 T 28-03-2018 CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 2 8 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 SUPERFAMILY SSF53335 241 341 6.65E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 SUPERFAMILY SSF53335 53 191 6.65E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS08465 1367fb233de908881e1d7b3e0d69e0cd 504 SUPERFAMILY SSF53335 1 18 6.65E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 Pfam PF00874 PRD domain 179 273 2.2E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 Pfam PF00874 PRD domain 76 162 1.3E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 SUPERFAMILY SSF63520 175 274 1.7E-25 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 Gene3D G3DSA:2.30.24.10 1 53 8.3E-24 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 Gene3D G3DSA:1.10.1790.10 169 276 5.8E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 Gene3D G3DSA:1.10.1790.10 54 167 2.6E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 SUPERFAMILY SSF50151 1 53 1.27E-17 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 Pfam PF03123 CAT RNA binding domain 1 56 8.5E-24 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 SMART SM01061 1 59 6.0E-27 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWM22_RS11175 5f36fcdb79b6faaeacb9b30dab53f13f 277 SUPERFAMILY SSF63520 60 166 2.22E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWM22_RS02780 44a60309c371b2c673b39e87b70c69e3 458 Pfam PF13751 Transposase DDE domain 322 439 4.6E-21 T 28-03-2018 IPR025668 Transposase DDE domain CWM22_RS02780 44a60309c371b2c673b39e87b70c69e3 458 Pfam PF05598 Transposase domain (DUF772) 54 129 1.6E-20 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWM22_RS04360 3976004fad1b249e994f4381440395f2 161 Pfam PF04073 Aminoacyl-tRNA editing domain 21 147 4.0E-22 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWM22_RS04360 3976004fad1b249e994f4381440395f2 161 SUPERFAMILY SSF55826 4 160 4.32E-39 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWM22_RS04360 3976004fad1b249e994f4381440395f2 161 Gene3D G3DSA:3.90.960.10 2 161 6.9E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWM22_RS02825 2bab784ce85374b533e4d09389a6c325 188 Hamap MF_01197 Cell division protein SepF [sepF]. 4 171 16.514 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CWM22_RS02825 2bab784ce85374b533e4d09389a6c325 188 Pfam PF04472 Cell division protein SepF 97 163 1.2E-14 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CWM22_RS01135 15f4230127a73f1024a582f7783618bc 233 Pfam PF03591 AzlC protein 15 155 3.3E-36 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease CWM22_RS09490 1577cfc6b3dd8bdd171aa0d467c903b5 219 Pfam PF04854 Protein of unknown function, DUF624 30 102 8.7E-9 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CWM22_RS01475 3e9327b4095092ec9a2138147b63cfcd 661 Pfam PF07242 Protein of unknown function (DUF1430) 561 660 3.7E-21 T 28-03-2018 IPR006541 Bacteriocin-associated integral membrane protein CWM22_RS01475 3e9327b4095092ec9a2138147b63cfcd 661 TIGRFAM TIGR01654 bact_immun_7tm: bacteriocin-associated integral membrane protein 2 660 7.5E-64 T 28-03-2018 IPR006541 Bacteriocin-associated integral membrane protein CWM22_RS04215 ca114f7ca3e312c30e490f9073e2e3ff 342 Gene3D G3DSA:3.10.520.10 2 309 2.4E-43 T 28-03-2018 CWM22_RS04215 ca114f7ca3e312c30e490f9073e2e3ff 342 SUPERFAMILY SSF143631 5 306 2.88E-82 T 28-03-2018 IPR003374 ApbE-like domain CWM22_RS04215 ca114f7ca3e312c30e490f9073e2e3ff 342 Pfam PF02424 ApbE family 11 290 2.7E-69 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CWM22_RS04215 ca114f7ca3e312c30e490f9073e2e3ff 342 PIRSF PIRSF006268 1 311 2.7E-82 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CWM22_RS02395 978c0ead376fdb44854bc2318805b260 82 Gene3D G3DSA:3.10.180.10 2 80 1.2E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS02395 978c0ead376fdb44854bc2318805b260 82 SUPERFAMILY SSF54593 24 79 6.55E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS01330 0f2b64d66786a478f6daee521db7161e 116 Gene3D G3DSA:1.10.10.60 51 102 3.2E-5 T 28-03-2018 CWM22_RS00350 0c94d082e9977b1400e5cfe051558c65 192 Pfam PF02517 CAAX protease self-immunity 95 186 1.3E-9 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS10895 b73f33d0b76a029c0d516ff356c21294 153 Gene3D G3DSA:3.40.630.30 1 153 9.1E-22 T 28-03-2018 CWM22_RS10895 b73f33d0b76a029c0d516ff356c21294 153 SUPERFAMILY SSF55729 4 150 6.45E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS10895 b73f33d0b76a029c0d516ff356c21294 153 Pfam PF13673 Acetyltransferase (GNAT) domain 38 150 1.2E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS03590 216a441947ae5426a17c7e45e564c152 395 Pfam PF04932 O-Antigen ligase 184 325 1.6E-8 T 28-03-2018 IPR007016 O-antigen ligase-related CWM22_RS03360 4bd6d80957c933bd83158782223491ae 536 Gene3D G3DSA:3.40.190.10 179 534 9.2E-48 T 28-03-2018 CWM22_RS03360 4bd6d80957c933bd83158782223491ae 536 SUPERFAMILY SSF53850 21 532 9.59E-88 T 28-03-2018 CWM22_RS03360 4bd6d80957c933bd83158782223491ae 536 Pfam PF01547 Bacterial extracellular solute-binding protein 65 371 1.3E-12 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CWM22_RS03585 8bb589206ff3d1f06502c15f8f8984e0 359 Gene3D G3DSA:3.40.50.2000 181 348 2.9E-31 T 28-03-2018 CWM22_RS03585 8bb589206ff3d1f06502c15f8f8984e0 359 SUPERFAMILY SSF53756 3 352 3.45E-57 T 28-03-2018 CWM22_RS03585 8bb589206ff3d1f06502c15f8f8984e0 359 Pfam PF00534 Glycosyl transferases group 1 181 334 1.5E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWM22_RS03585 8bb589206ff3d1f06502c15f8f8984e0 359 Gene3D G3DSA:3.40.50.2000 1 180 8.7E-7 T 28-03-2018 CWM22_RS03205 7b7cb6c961ebaf1af69c1aa9f33dbd24 504 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 202 2.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS03205 7b7cb6c961ebaf1af69c1aa9f33dbd24 504 SUPERFAMILY SSF161098 15 193 2.35E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS03205 7b7cb6c961ebaf1af69c1aa9f33dbd24 504 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 233 499 4.9E-60 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CWM22_RS03205 7b7cb6c961ebaf1af69c1aa9f33dbd24 504 SUPERFAMILY SSF53850 233 502 1.74E-69 T 28-03-2018 CWM22_RS03205 7b7cb6c961ebaf1af69c1aa9f33dbd24 504 Gene3D G3DSA:3.40.190.10 385 503 4.4E-24 T 28-03-2018 CWM22_RS03205 7b7cb6c961ebaf1af69c1aa9f33dbd24 504 Gene3D G3DSA:3.40.190.10 223 384 1.5E-33 T 28-03-2018 CWM22_RS03205 7b7cb6c961ebaf1af69c1aa9f33dbd24 504 Gene3D G3DSA:1.10.3720.10 2 208 1.1E-25 T 28-03-2018 CWM22_RS10805 0aecf83f34a2ea72c24466863bf050d8 486 PIRSF PIRSF005353 1 485 3.6E-159 T 28-03-2018 IPR026033 Purine permease PbuG-like CWM22_RS10805 0aecf83f34a2ea72c24466863bf050d8 486 Pfam PF00860 Permease family 198 445 3.9E-24 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWM22_RS10805 0aecf83f34a2ea72c24466863bf050d8 486 Pfam PF00860 Permease family 17 156 1.5E-13 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWM22_RS03430 c3f2b7a070b629c63ba05f2290db87e2 284 Pfam PF13509 S1 domain 9 62 2.8E-9 T 28-03-2018 CWM22_RS03430 c3f2b7a070b629c63ba05f2290db87e2 284 Gene3D G3DSA:1.10.10.10 224 283 5.3E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS03430 c3f2b7a070b629c63ba05f2290db87e2 284 PIRSF PIRSF012524 1 284 2.4E-110 T 28-03-2018 IPR014464 Conserved virulence factor B CWM22_RS03430 c3f2b7a070b629c63ba05f2290db87e2 284 Gene3D G3DSA:2.40.50.140 152 221 1.2E-8 T 28-03-2018 CWM22_RS03430 c3f2b7a070b629c63ba05f2290db87e2 284 Gene3D G3DSA:2.40.50.140 52 132 0.21 T 28-03-2018 CWM22_RS03430 c3f2b7a070b629c63ba05f2290db87e2 284 SUPERFAMILY SSF50249 147 218 2.12E-6 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS06700 ed1a9d004f3ad365260c32d7e1993988 313 SUPERFAMILY SSF55874 156 310 2.75E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS06700 ed1a9d004f3ad365260c32d7e1993988 313 Gene3D G3DSA:3.30.565.10 132 310 1.6E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS06700 ed1a9d004f3ad365260c32d7e1993988 313 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 210 310 7.4E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS06700 ed1a9d004f3ad365260c32d7e1993988 313 SMART SM00387 209 313 5.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS09980 cb80c5526875678e74af3589861c535f 128 Gene3D G3DSA:2.40.128.20 1 128 4.1E-26 T 28-03-2018 IPR012674 Calycin CWM22_RS09980 cb80c5526875678e74af3589861c535f 128 Pfam PF09148 Domain of unknown function (DUF1934) 3 125 1.9E-21 T 28-03-2018 IPR015231 Protein of unknown function DUF1934 CWM22_RS09980 cb80c5526875678e74af3589861c535f 128 SUPERFAMILY SSF50814 1 128 3.88E-36 T 28-03-2018 IPR012674 Calycin CWM22_RS01580 105af1d80f698b5120dafefabea481a3 126 Pfam PF03788 LrgA family 15 107 5.6E-29 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 CWM22_RS05315 e6af982db1a87d9db00c0375fb03ba1a 230 Pfam PF07722 Peptidase C26 4 210 4.6E-63 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CWM22_RS05315 e6af982db1a87d9db00c0375fb03ba1a 230 SUPERFAMILY SSF52317 29 216 3.21E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS05315 e6af982db1a87d9db00c0375fb03ba1a 230 Gene3D G3DSA:3.40.50.880 1 229 6.3E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS12525 92fa34d1d02e1f5418de8ab3b0bbd138 482 Pfam PF03611 PTS system sugar-specific permease component 14 427 3.9E-112 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CWM22_RS05410 53219b559ef7e6f30a932402d7d3935f 426 SUPERFAMILY SSF53383 6 423 1.02E-127 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS05410 53219b559ef7e6f30a932402d7d3935f 426 Gene3D G3DSA:3.40.640.10 5 290 7.3E-65 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS05410 53219b559ef7e6f30a932402d7d3935f 426 PIRSF PIRSF001434 1 426 2.6E-132 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWM22_RS05410 53219b559ef7e6f30a932402d7d3935f 426 Gene3D G3DSA:3.90.1150.10 292 426 1.1E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS05410 53219b559ef7e6f30a932402d7d3935f 426 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWM22_RS05410 53219b559ef7e6f30a932402d7d3935f 426 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 423 7.1E-142 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWM22_RS05410 53219b559ef7e6f30a932402d7d3935f 426 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 7 423 1.7E-194 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CWM22_RS01210 208d2406eee07a2fd09048ed11493209 182 SUPERFAMILY SSF55729 2 170 7.21E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS01210 208d2406eee07a2fd09048ed11493209 182 Pfam PF13302 Acetyltransferase (GNAT) domain 4 145 3.8E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS01210 208d2406eee07a2fd09048ed11493209 182 Gene3D G3DSA:3.40.630.30 1 182 2.8E-21 T 28-03-2018 CWM22_RS00820 73a7caa6a289446906431db8ad555b40 270 Gene3D G3DSA:1.10.3470.10 3 270 2.1E-23 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS00820 73a7caa6a289446906431db8ad555b40 270 Pfam PF00950 ABC 3 transport family 9 264 1.2E-76 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CWM22_RS00820 73a7caa6a289446906431db8ad555b40 270 SUPERFAMILY SSF81345 5 261 1.96E-34 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWM22_RS04225 37ba7b93cfea1b4ad397d49a0a9e468f 80 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 1.4E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS04225 37ba7b93cfea1b4ad397d49a0a9e468f 80 SUPERFAMILY SSF143800 1 79 1.41E-24 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS04225 37ba7b93cfea1b4ad397d49a0a9e468f 80 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 27.695 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS04225 37ba7b93cfea1b4ad397d49a0a9e468f 80 Pfam PF01197 Ribosomal protein L31 1 78 2.9E-29 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS04225 37ba7b93cfea1b4ad397d49a0a9e468f 80 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS04225 37ba7b93cfea1b4ad397d49a0a9e468f 80 PRINTS PR01249 Ribosomal protein L31 signature 44 59 7.3E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS04225 37ba7b93cfea1b4ad397d49a0a9e468f 80 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.3E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS04225 37ba7b93cfea1b4ad397d49a0a9e468f 80 PRINTS PR01249 Ribosomal protein L31 signature 59 77 7.3E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS03720 ecf2fcdb110fdba1e093cade98f95864 146 Pfam PF13673 Acetyltransferase (GNAT) domain 69 143 2.0E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS03720 ecf2fcdb110fdba1e093cade98f95864 146 SUPERFAMILY SSF55729 14 143 9.83E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS03720 ecf2fcdb110fdba1e093cade98f95864 146 Gene3D G3DSA:3.40.630.30 1 143 1.2E-24 T 28-03-2018 CWM22_RS13125 91711184c9dc5c10c93e4fe4714ca007 299 Gene3D G3DSA:1.10.3100.10 2 151 4.6E-12 T 28-03-2018 IPR027910 YdiL-like domain CWM22_RS13125 91711184c9dc5c10c93e4fe4714ca007 299 SUPERFAMILY SSF47413 1 63 1.01E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS07165 11cc78e8f6dc2bfd48a067778f593d1b 251 Pfam PF04445 Putative SAM-dependent methyltransferase 87 218 5.8E-17 T 28-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 CWM22_RS07165 11cc78e8f6dc2bfd48a067778f593d1b 251 SUPERFAMILY SSF53335 2 245 3.94E-50 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWM22_RS07165 11cc78e8f6dc2bfd48a067778f593d1b 251 Gene3D G3DSA:3.40.50.150 64 248 1.1E-18 T 28-03-2018 CWM22_RS11350 91de98a00950e27d1f6a76f5bea742a7 300 Gene3D G3DSA:1.10.3720.10 21 287 2.9E-35 T 28-03-2018 CWM22_RS11350 91de98a00950e27d1f6a76f5bea742a7 300 SUPERFAMILY SSF161098 89 283 4.58E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS11350 91de98a00950e27d1f6a76f5bea742a7 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 296 7.6E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS07105 7fedc404f687a73b465daed480d0192b 266 SUPERFAMILY SSF161098 2 260 7.06E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS07105 7fedc404f687a73b465daed480d0192b 266 Gene3D G3DSA:1.10.3720.10 5 262 5.9E-36 T 28-03-2018 CWM22_RS07105 7fedc404f687a73b465daed480d0192b 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 61 261 3.8E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS07075 79d5f7dbfc8691dd7c0d1bb19b85c374 373 Pfam PF02371 Transposase IS116/IS110/IS902 family 234 301 3.2E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CWM22_RS07075 79d5f7dbfc8691dd7c0d1bb19b85c374 373 Pfam PF01548 Transposase 9 155 8.5E-11 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CWM22_RS03825 e1f387d5a27898995cbf18b8be869eff 341 Pfam PF01032 FecCD transport family 29 337 3.9E-86 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWM22_RS03825 e1f387d5a27898995cbf18b8be869eff 341 Gene3D G3DSA:1.10.3470.10 12 340 2.5E-63 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS03825 e1f387d5a27898995cbf18b8be869eff 341 SUPERFAMILY SSF81345 12 337 3.4E-77 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWM22_RS09025 c5a5ba4c632bc974af3802bcccb9d24c 1049 SUPERFAMILY SSF52540 733 913 6.9E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09025 c5a5ba4c632bc974af3802bcccb9d24c 1049 SUPERFAMILY SSF52540 340 499 6.9E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09025 c5a5ba4c632bc974af3802bcccb9d24c 1049 Gene3D G3DSA:3.40.50.300 233 931 2.9E-30 T 28-03-2018 CWM22_RS09025 c5a5ba4c632bc974af3802bcccb9d24c 1049 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 335 596 2.6E-16 T 28-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 CWM22_RS09025 c5a5ba4c632bc974af3802bcccb9d24c 1049 Pfam PF12696 TraM recognition site of TraD and TraG 787 906 7.8E-25 T 28-03-2018 IPR032689 TraD/TraG, TraM recognition site CWM22_RS12170 3ac81eddd7a88fb09d30cab801c0139e 85 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 2.5E-37 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CWM22_RS12170 3ac81eddd7a88fb09d30cab801c0139e 85 Gene3D G3DSA:3.30.2310.20 1 84 7.8E-26 T 28-03-2018 CWM22_RS12170 3ac81eddd7a88fb09d30cab801c0139e 85 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 3.3E-33 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CWM22_RS12170 3ac81eddd7a88fb09d30cab801c0139e 85 SUPERFAMILY SSF143011 1 83 1.57E-26 T 28-03-2018 IPR035095 Toxin RelE-like domain CWM22_RS12475 1b8c520cf034f2ba886a777df7021cc2 173 Pfam PF14437 MafB19-like deaminase 7 153 5.1E-37 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CWM22_RS12475 1b8c520cf034f2ba886a777df7021cc2 173 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 94 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWM22_RS12475 1b8c520cf034f2ba886a777df7021cc2 173 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 12 153 45.877 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CWM22_RS12475 1b8c520cf034f2ba886a777df7021cc2 173 SUPERFAMILY SSF53927 4 157 4.35E-53 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWM22_RS12475 1b8c520cf034f2ba886a777df7021cc2 173 Gene3D G3DSA:3.40.140.10 1 163 1.1E-52 T 28-03-2018 CWM22_RS08605 3260b33470e42cd79794e1f3ceea83ea 423 Pfam PF05816 Toxic anion resistance protein (TelA) 64 389 1.5E-21 T 28-03-2018 IPR008863 Toxic anion resistance CWM22_RS01785 d1336af7b2681ab6d357bdbc735dfcd8 197 TIGRFAM TIGR02185 Trep_Strep: putative ECF transporter S component, Trep_Strep family 4 191 1.6E-39 T 28-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane CWM22_RS01785 d1336af7b2681ab6d357bdbc735dfcd8 197 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 6 191 2.1E-52 T 28-03-2018 IPR011733 Conserved hypothetical CHP02185, integral membrane CWM22_RS12210 01c0d700e4972964d21d67540c342aae 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWM22_RS12210 01c0d700e4972964d21d67540c342aae 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 5.0E-6 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS12210 01c0d700e4972964d21d67540c342aae 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 2 44 1.7E-21 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS12210 01c0d700e4972964d21d67540c342aae 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.08 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS12210 01c0d700e4972964d21d67540c342aae 45 Pfam PF00468 Ribosomal protein L34 2 44 1.2E-22 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS10075 04e6cb3ff605b07ae5dab1c8f6feaa22 416 Pfam PF02687 FtsX-like permease family 319 409 2.3E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWM22_RS10075 04e6cb3ff605b07ae5dab1c8f6feaa22 416 Pfam PF12704 MacB-like periplasmic core domain 18 254 2.0E-27 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CWM22_RS08515 8c8d03469a96d8558eec46d62a07c1d9 83 Gene3D G3DSA:1.10.10.60 22 68 6.2E-7 T 28-03-2018 CWM22_RS11395 eb1ebf3e0c117e9eb8b5301212537146 420 SUPERFAMILY SSF101960 4 417 9.55E-113 T 28-03-2018 CWM22_RS11395 eb1ebf3e0c117e9eb8b5301212537146 420 Pfam PF01458 Uncharacterized protein family (UPF0051) 166 392 8.8E-55 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CWM22_RS11395 eb1ebf3e0c117e9eb8b5301212537146 420 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 132 409 2.1E-74 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CWM22_RS02290 2aaa38a18517d188a97eed73a87b61e3 362 SUPERFAMILY SSF52374 185 211 5.63E-17 T 28-03-2018 CWM22_RS02290 2aaa38a18517d188a97eed73a87b61e3 362 SUPERFAMILY SSF52374 9 137 5.63E-17 T 28-03-2018 CWM22_RS02290 2aaa38a18517d188a97eed73a87b61e3 362 Pfam PF05636 HIGH Nucleotidyl Transferase 2 354 7.7E-108 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CWM22_RS02290 2aaa38a18517d188a97eed73a87b61e3 362 Gene3D G3DSA:3.40.50.620 1 216 3.2E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWM22_RS02290 2aaa38a18517d188a97eed73a87b61e3 362 Hamap MF_01539 UPF0348 protein . 1 360 34.395 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CWM22_RS06810 44aaf00eb438ca56bc1779258d450397 262 SUPERFAMILY SSF144015 37 248 1.23E-61 T 28-03-2018 CWM22_RS02895 b9b2f41fe0b31eedc0ed1781b4a7a680 46 Pfam PF04650 YSIRK type signal peptide 6 25 5.2E-7 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS02895 b9b2f41fe0b31eedc0ed1781b4a7a680 46 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 6 35 6.7E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWM22_RS11605 c48661590aef25cfb273c6a08b1c4bbf 554 Gene3D G3DSA:3.30.565.10 276 537 3.2E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS11605 c48661590aef25cfb273c6a08b1c4bbf 554 Pfam PF06580 Histidine kinase 335 411 3.4E-20 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CWM22_RS11605 c48661590aef25cfb273c6a08b1c4bbf 554 SUPERFAMILY SSF55874 429 536 1.13E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWM22_RS10395 5c8afeb02ca015bf9b99489f5c97024d 152 SUPERFAMILY SSF54631 17 137 6.57E-22 T 28-03-2018 CWM22_RS10395 5c8afeb02ca015bf9b99489f5c97024d 152 Pfam PF00571 CBS domain 90 136 2.0E-6 T 28-03-2018 IPR000644 CBS domain CWM22_RS10395 5c8afeb02ca015bf9b99489f5c97024d 152 Gene3D G3DSA:3.10.580.10 2 148 3.1E-16 T 28-03-2018 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 Pfam PF00459 Inositol monophosphatase family 5 235 1.6E-42 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 Gene3D G3DSA:3.30.540.10 1 149 3.3E-36 T 28-03-2018 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 Gene3D G3DSA:3.40.190.80 150 251 2.0E-14 T 28-03-2018 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 SUPERFAMILY SSF56655 3 247 1.26E-59 T 28-03-2018 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 201 225 4.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 4.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 4.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 171 192 4.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 4.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWM22_RS05025 29eed06aa6393cda0e95f02dd7170e6e 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 4.2E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWM22_RS12465 f9c17ffcc42ba95d792734a33a2a1927 180 SUPERFAMILY SSF52540 3 141 1.42E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13015 18b437d6219b5e420b1d1b089afa7c6c 146 Pfam PF11457 Protein of unknown function (DUF3021) 1 146 1.3E-32 T 28-03-2018 IPR021560 Protein of unknown function DUF3021 CWM22_RS07900 8f149df0c4421d9c8db00de29b935f46 197 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 17 188 4.9E-39 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CWM22_RS07900 8f149df0c4421d9c8db00de29b935f46 197 SUPERFAMILY SSF51182 17 192 9.19E-52 T 28-03-2018 IPR011051 RmlC-like cupin domain CWM22_RS07900 8f149df0c4421d9c8db00de29b935f46 197 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 11 195 3.0E-105 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CWM22_RS07900 8f149df0c4421d9c8db00de29b935f46 197 Gene3D G3DSA:2.60.120.10 1 197 5.8E-49 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWM22_RS02045 295600e6c1e427a1b6e49e2a4fb1b7e2 193 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 190 15.856 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CWM22_RS02045 295600e6c1e427a1b6e49e2a4fb1b7e2 193 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 83 1.5E-8 T 28-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CWM22_RS02045 295600e6c1e427a1b6e49e2a4fb1b7e2 193 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 13 94 1.3E-30 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CWM22_RS12930 1342d5f5967dc5748476ac54791b22ab 828 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 796 827 2.9E-5 T 28-03-2018 CWM22_RS12930 1342d5f5967dc5748476ac54791b22ab 828 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 262 609 2.4E-79 T 28-03-2018 IPR027607 SEC10/PgrA surface exclusion domain CWM22_RS12930 1342d5f5967dc5748476ac54791b22ab 828 Gene3D G3DSA:1.25.40.10 194 608 2.5E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWM22_RS12930 1342d5f5967dc5748476ac54791b22ab 828 Gene3D G3DSA:1.10.287.620 39 179 5.3E-8 T 28-03-2018 CWM22_RS12930 1342d5f5967dc5748476ac54791b22ab 828 Gene3D G3DSA:1.10.287.620 609 747 8.5E-10 T 28-03-2018 CWM22_RS07130 8c6956012f3c043cc004414c3731cadf 307 SUPERFAMILY SSF88713 106 290 1.06E-38 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWM22_RS07130 8c6956012f3c043cc004414c3731cadf 307 Pfam PF01522 Polysaccharide deacetylase 144 268 8.9E-28 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWM22_RS07130 8c6956012f3c043cc004414c3731cadf 307 Gene3D G3DSA:3.20.20.370 39 303 3.8E-43 T 28-03-2018 CWM22_RS09005 479cfa4b15d248253d715bf99b7a492f 101 Pfam PF17332 Uncharacterized protein pXO2-11 5 94 1.6E-8 T 28-03-2018 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 Gene3D G3DSA:1.20.1080.10 1 281 5.5E-78 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 SUPERFAMILY SSF81338 4 165 1.44E-58 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 SUPERFAMILY SSF81338 192 280 1.44E-58 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 PRINTS PR00783 Major intrinsic protein family signature 49 73 5.2E-38 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 PRINTS PR00783 Major intrinsic protein family signature 86 105 5.2E-38 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 PRINTS PR00783 Major intrinsic protein family signature 150 168 5.2E-38 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 PRINTS PR00783 Major intrinsic protein family signature 7 26 5.2E-38 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 PRINTS PR00783 Major intrinsic protein family signature 208 230 5.2E-38 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 PRINTS PR00783 Major intrinsic protein family signature 259 279 5.2E-38 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 Pfam PF00230 Major intrinsic protein 7 272 2.8E-38 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS01595 6bbba5e90bea28b44ce9c93f4f8cd1aa 281 ProSitePatterns PS00221 MIP family signature. 67 75 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWM22_RS08130 b658ab26d70f289683272cf3c55289b5 516 Gene3D G3DSA:1.20.1250.20 230 477 1.7E-8 T 28-03-2018 CWM22_RS08130 b658ab26d70f289683272cf3c55289b5 516 Gene3D G3DSA:1.20.1250.20 16 222 5.1E-8 T 28-03-2018 CWM22_RS08130 b658ab26d70f289683272cf3c55289b5 516 Pfam PF13347 MFS/sugar transport protein 37 467 4.2E-36 T 28-03-2018 CWM22_RS08130 b658ab26d70f289683272cf3c55289b5 516 SUPERFAMILY SSF103473 15 460 1.96E-17 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWM22_RS06345 75d2e96e9b8d40684caeeccffc894093 933 SUPERFAMILY SSF54001 803 914 2.26E-15 T 28-03-2018 CWM22_RS06345 75d2e96e9b8d40684caeeccffc894093 933 Pfam PF05257 CHAP domain 808 907 1.7E-15 T 28-03-2018 IPR007921 CHAP domain CWM22_RS06345 75d2e96e9b8d40684caeeccffc894093 933 Gene3D G3DSA:2.70.70.10 420 580 8.4E-7 T 28-03-2018 CWM22_RS02725 866c0f7c38ac671b6cdfb3ee1c08e51b 899 Pfam PF04851 Type III restriction enzyme, res subunit 407 550 4.0E-18 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWM22_RS02725 866c0f7c38ac671b6cdfb3ee1c08e51b 899 Gene3D G3DSA:3.40.50.300 380 574 5.6E-29 T 28-03-2018 CWM22_RS02725 866c0f7c38ac671b6cdfb3ee1c08e51b 899 SMART SM00487 389 576 7.0E-19 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWM22_RS02725 866c0f7c38ac671b6cdfb3ee1c08e51b 899 Gene3D G3DSA:3.40.50.300 603 742 2.7E-14 T 28-03-2018 CWM22_RS02725 866c0f7c38ac671b6cdfb3ee1c08e51b 899 SUPERFAMILY SSF52540 597 730 8.07E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02725 866c0f7c38ac671b6cdfb3ee1c08e51b 899 SUPERFAMILY SSF52540 404 551 8.07E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS02725 866c0f7c38ac671b6cdfb3ee1c08e51b 899 Pfam PF00271 Helicase conserved C-terminal domain 618 727 1.4E-7 T 28-03-2018 IPR001650 Helicase, C-terminal CWM22_RS10875 27421a0e91441c3b82eed982aee0dd96 191 Gene3D G3DSA:3.90.220.20 1 173 1.0E-12 T 28-03-2018 CWM22_RS10875 27421a0e91441c3b82eed982aee0dd96 191 SUPERFAMILY SSF116734 2 160 3.27E-13 T 28-03-2018 CWM22_RS10875 27421a0e91441c3b82eed982aee0dd96 191 Pfam PF01420 Type I restriction modification DNA specificity domain 54 158 1.3E-4 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CWM22_RS08010 d5282577dc114e73d6e7e4c85c493237 436 Pfam PF02447 GntP family permease 5 431 4.2E-9 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWM22_RS06225 beb37db9f8a47e41da2ce419df7b6e60 432 SUPERFAMILY SSF53850 20 431 1.92E-45 T 28-03-2018 CWM22_RS06225 beb37db9f8a47e41da2ce419df7b6e60 432 Pfam PF13416 Bacterial extracellular solute-binding protein 65 358 3.7E-21 T 28-03-2018 CWM22_RS06225 beb37db9f8a47e41da2ce419df7b6e60 432 Gene3D G3DSA:3.40.190.10 26 209 2.5E-26 T 28-03-2018 CWM22_RS06225 beb37db9f8a47e41da2ce419df7b6e60 432 Gene3D G3DSA:3.40.190.10 218 384 1.2E-9 T 28-03-2018 CWM22_RS10055 79d563dbcbb99f97c6868719b7262a32 160 PIRSF PIRSF006181 5 159 4.2E-52 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CWM22_RS10055 79d563dbcbb99f97c6868719b7262a32 160 Gene3D G3DSA:3.90.960.10 3 158 5.9E-28 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWM22_RS10055 79d563dbcbb99f97c6868719b7262a32 160 Pfam PF04073 Aminoacyl-tRNA editing domain 38 147 5.1E-20 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWM22_RS10055 79d563dbcbb99f97c6868719b7262a32 160 SUPERFAMILY SSF55826 7 155 2.09E-34 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWM22_RS06040 44d1389ae42f73dd6a2e3c1612095feb 103 Pfam PF00581 Rhodanese-like domain 12 98 1.4E-12 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS06040 44d1389ae42f73dd6a2e3c1612095feb 103 SUPERFAMILY SSF52821 5 97 9.82E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS06040 44d1389ae42f73dd6a2e3c1612095feb 103 SMART SM00450 11 103 4.5E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS06040 44d1389ae42f73dd6a2e3c1612095feb 103 Gene3D G3DSA:3.40.250.10 1 99 1.9E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CWM22_RS07785 e9f9c0d59a0218fbb520d7cc0788d7cd 371 SUPERFAMILY SSF51695 116 356 5.49E-19 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS07785 e9f9c0d59a0218fbb520d7cc0788d7cd 371 Gene3D G3DSA:3.20.20.190 112 357 1.9E-22 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWM22_RS10270 74db90d2557945c6d2976f71e83f6827 349 SUPERFAMILY SSF54211 157 343 1.67E-23 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWM22_RS10270 74db90d2557945c6d2976f71e83f6827 349 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 232 309 1.0E-6 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CWM22_RS10270 74db90d2557945c6d2976f71e83f6827 349 Pfam PF13180 PDZ domain 132 195 3.1E-6 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWM22_RS10270 74db90d2557945c6d2976f71e83f6827 349 Gene3D G3DSA:3.30.230.10 40 349 2.0E-33 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWM22_RS12115 ad9e6d8cf36f5174788b8832173ecb23 111 Gene3D G3DSA:3.30.2310.20 1 106 7.5E-9 T 28-03-2018 CWM22_RS12115 ad9e6d8cf36f5174788b8832173ecb23 111 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 10 106 1.2E-15 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CWM22_RS07670 005e962a81500b2f2b02ee3a3749d1d7 450 Pfam PF03050 Transposase IS66 family 117 393 2.0E-82 T 28-03-2018 IPR004291 Transposase, IS66 CWM22_RS07670 005e962a81500b2f2b02ee3a3749d1d7 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 51 95 2.8E-13 T 28-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CWM22_RS07670 005e962a81500b2f2b02ee3a3749d1d7 450 Pfam PF13817 IS66 C-terminal element 400 441 1.1E-8 T 28-03-2018 CWM22_RS12780 9386f999fed835d394dbc4b869870396 156 Pfam PF11217 Protein of unknown function (DUF3013) 1 155 5.0E-60 T 28-03-2018 IPR021380 Protein of unknown function DUF3013 CWM22_RS12080 f9d5f6ae606d6f107d68191a1401f033 412 Gene3D G3DSA:1.20.5.1230 27 389 1.8E-9 T 28-03-2018 CWM22_RS12080 f9d5f6ae606d6f107d68191a1401f033 412 Pfam PF02646 RmuC family 106 396 2.2E-71 T 28-03-2018 IPR003798 DNA recombination RmuC CWM22_RS07600 e75379cb32dcd530b540ecdb01a03e5a 440 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 189 357 6.5E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWM22_RS07600 e75379cb32dcd530b540ecdb01a03e5a 440 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 189 357 3.3E-22 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWM22_RS06645 f6761cf944ecc5383ec0c013aba35eca 334 Pfam PF06224 Winged helix DNA-binding domain 28 324 1.0E-27 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 Gene3D G3DSA:3.30.860.10 1 92 9.3E-41 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 SUPERFAMILY SSF54570 3 84 6.28E-35 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 Pfam PF00203 Ribosomal protein S19 3 83 7.9E-37 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 PIRSF PIRSF002144 1 93 2.1E-32 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 2.2E-47 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.494 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.1E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.1E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS00515 87a0287eaafec2513997c7bf3f140ccb 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.1E-23 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWM22_RS11110 4a178716d4de04197359e509e3e0bf3c 449 PIRSF PIRSF006351 4 449 1.9E-126 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWM22_RS11110 4a178716d4de04197359e509e3e0bf3c 449 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 19 445 6.5E-86 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWM22_RS11110 4a178716d4de04197359e509e3e0bf3c 449 Pfam PF02378 Phosphotransferase system, EIIC 36 373 9.4E-45 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWM22_RS08925 73a4cfe2dfeaf6adcb29bbc8f0bafa1c 279 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 53 270 4.7E-48 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS08925 73a4cfe2dfeaf6adcb29bbc8f0bafa1c 279 Gene3D G3DSA:3.40.190.10 42 147 1.4E-33 T 28-03-2018 CWM22_RS08925 73a4cfe2dfeaf6adcb29bbc8f0bafa1c 279 Gene3D G3DSA:3.40.190.10 148 235 2.4E-21 T 28-03-2018 CWM22_RS08925 73a4cfe2dfeaf6adcb29bbc8f0bafa1c 279 SUPERFAMILY SSF53850 20 273 1.39E-57 T 28-03-2018 CWM22_RS08925 73a4cfe2dfeaf6adcb29bbc8f0bafa1c 279 SMART SM00062 52 273 3.7E-53 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWM22_RS01605 b9015f6870565898cacaf33910b8476e 204 ProSitePatterns PS00893 Nudix box signature. 58 79 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWM22_RS01605 b9015f6870565898cacaf33910b8476e 204 PRINTS PR00502 NUDIX hydrolase family signature 53 67 5.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWM22_RS01605 b9015f6870565898cacaf33910b8476e 204 PRINTS PR00502 NUDIX hydrolase family signature 67 82 5.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWM22_RS01605 b9015f6870565898cacaf33910b8476e 204 Pfam PF00293 NUDIX domain 38 132 3.1E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWM22_RS01605 b9015f6870565898cacaf33910b8476e 204 Gene3D G3DSA:3.90.79.10 3 199 2.8E-31 T 28-03-2018 CWM22_RS01605 b9015f6870565898cacaf33910b8476e 204 SUPERFAMILY SSF55811 21 190 2.84E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS06050 0ea91ba0eefc9fcead5aa71a3b2f84ac 280 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 75 277 9.9E-74 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CWM22_RS06050 0ea91ba0eefc9fcead5aa71a3b2f84ac 280 Gene3D G3DSA:3.40.50.450 105 254 4.5E-34 T 28-03-2018 CWM22_RS06050 0ea91ba0eefc9fcead5aa71a3b2f84ac 280 Pfam PF02481 DNA recombination-mediator protein A 74 269 1.0E-75 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CWM22_RS06050 0ea91ba0eefc9fcead5aa71a3b2f84ac 280 SUPERFAMILY SSF102405 75 274 1.53E-33 T 28-03-2018 CWM22_RS02300 cc8b9238445274df27f1ea450e06755b 146 Pfam PF03682 Uncharacterised protein family (UPF0158) 6 143 7.5E-16 T 28-03-2018 IPR005361 Uncharacterised protein family UPF0158 CWM22_RS09565 7b819bea139f172ed2cda3ae4b870d88 239 SUPERFAMILY SSF54001 19 127 1.96E-12 T 28-03-2018 CWM22_RS09565 7b819bea139f172ed2cda3ae4b870d88 239 Pfam PF05257 CHAP domain 24 112 1.5E-12 T 28-03-2018 IPR007921 CHAP domain CWM22_RS09565 7b819bea139f172ed2cda3ae4b870d88 239 Pfam PF08460 Bacterial SH3 domain 162 222 3.7E-14 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CWM22_RS09565 7b819bea139f172ed2cda3ae4b870d88 239 Gene3D G3DSA:2.30.30.410 140 239 2.8E-15 T 28-03-2018 CWM22_RS09565 7b819bea139f172ed2cda3ae4b870d88 239 SMART SM00287 163 230 1.3E-10 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CWM22_RS10405 8da3296a917c9f255f46fa59e2efa5f3 336 Gene3D G3DSA:3.90.950.10 121 329 2.7E-71 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CWM22_RS10405 8da3296a917c9f255f46fa59e2efa5f3 336 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 134 328 47.523 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CWM22_RS10405 8da3296a917c9f255f46fa59e2efa5f3 336 SUPERFAMILY SSF52972 135 326 4.97E-64 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CWM22_RS10405 8da3296a917c9f255f46fa59e2efa5f3 336 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 136 326 2.1E-57 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CWM22_RS10405 8da3296a917c9f255f46fa59e2efa5f3 336 Pfam PF01725 Ham1 family 136 324 2.3E-54 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CWM22_RS09120 62209e5fc79f11b5050a451413740075 151 Gene3D G3DSA:1.10.1220.10 1 25 0.09 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CWM22_RS00805 affa0deb7ebf1c469cf761db4423c129 46 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 5 46 2.7E-11 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) CWM22_RS09455 2d59bfcd643504579557f90acf49fc7e 133 Pfam PF01219 Prokaryotic diacylglycerol kinase 23 124 2.3E-32 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CWM22_RS09455 2d59bfcd643504579557f90acf49fc7e 133 Gene3D G3DSA:1.10.3830.10 13 126 4.6E-37 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CWM22_RS09455 2d59bfcd643504579557f90acf49fc7e 133 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 76 87 - T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CWM22_RS06985 b3aea341bd0f32fe4b5ba5f8fdbfeb60 124 Pfam PF06619 Protein of unknown function (DUF1149) 1 124 4.8E-46 T 28-03-2018 IPR009530 Protein of unknown function DUF1149 CWM22_RS06985 b3aea341bd0f32fe4b5ba5f8fdbfeb60 124 PIRSF PIRSF031568 1 124 6.3E-51 T 28-03-2018 IPR009530 Protein of unknown function DUF1149 CWM22_RS06985 b3aea341bd0f32fe4b5ba5f8fdbfeb60 124 Gene3D G3DSA:3.10.420.10 1 124 2.6E-44 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CWM22_RS06985 b3aea341bd0f32fe4b5ba5f8fdbfeb60 124 SUPERFAMILY SSF54611 1 124 1.41E-47 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CWM22_RS09540 2a49b43fed54ed895965c22d433ce71e 134 Gene3D G3DSA:3.30.2390.10 3 74 2.8E-14 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like CWM22_RS09540 2a49b43fed54ed895965c22d433ce71e 134 SUPERFAMILY SSF143100 4 67 2.22E-15 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like CWM22_RS09540 2a49b43fed54ed895965c22d433ce71e 134 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 5 110 7.1E-17 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system CWM22_RS11850 c7db04d587914e04631ab4ff62724d21 329 Pfam PF02733 Dak1 domain 17 326 4.4E-118 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWM22_RS11850 c7db04d587914e04631ab4ff62724d21 329 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 6.0E-151 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 CWM22_RS11850 c7db04d587914e04631ab4ff62724d21 329 Gene3D G3DSA:3.40.50.10440 11 183 4.1E-71 T 28-03-2018 CWM22_RS11850 c7db04d587914e04631ab4ff62724d21 329 SUPERFAMILY SSF82549 10 329 7.85E-123 T 28-03-2018 CWM22_RS11850 c7db04d587914e04631ab4ff62724d21 329 Gene3D G3DSA:3.30.1180.20 184 329 2.4E-43 T 28-03-2018 CWM22_RS05540 6dc7a2ea394745964ffec0fc07968d89 298 Gene3D G3DSA:3.40.50.300 1 298 5.2E-41 T 28-03-2018 CWM22_RS05540 6dc7a2ea394745964ffec0fc07968d89 298 Pfam PF13614 AAA domain 42 214 4.0E-32 T 28-03-2018 IPR025669 AAA domain CWM22_RS05540 6dc7a2ea394745964ffec0fc07968d89 298 SUPERFAMILY SSF52540 38 292 1.77E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04525 6599c9295e2955669c16f2a86a59e153 2422 Pfam PF00746 LPXTG cell wall anchor motif 2376 2415 5.1E-8 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWM22_RS04525 6599c9295e2955669c16f2a86a59e153 2422 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2381 2414 1.2E-6 T 28-03-2018 CWM22_RS13265 59162484e992ebd3b7144a60b5a225c4 143 PRINTS PR00502 NUDIX hydrolase family signature 51 66 3.1E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWM22_RS13265 59162484e992ebd3b7144a60b5a225c4 143 PRINTS PR00502 NUDIX hydrolase family signature 37 51 3.1E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWM22_RS13265 59162484e992ebd3b7144a60b5a225c4 143 SUPERFAMILY SSF55811 9 137 2.3E-23 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS13265 59162484e992ebd3b7144a60b5a225c4 143 Pfam PF00293 NUDIX domain 9 132 7.0E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWM22_RS13265 59162484e992ebd3b7144a60b5a225c4 143 Gene3D G3DSA:3.90.79.10 4 132 7.0E-21 T 28-03-2018 CWM22_RS07805 5852cc21793e4148ba6d3206947119d6 417 Pfam PF13439 Glycosyltransferase Family 4 15 138 8.5E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CWM22_RS07805 5852cc21793e4148ba6d3206947119d6 417 Pfam PF00534 Glycosyl transferases group 1 185 337 4.3E-25 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWM22_RS07805 5852cc21793e4148ba6d3206947119d6 417 Gene3D G3DSA:3.40.50.2000 196 353 5.7E-27 T 28-03-2018 CWM22_RS07805 5852cc21793e4148ba6d3206947119d6 417 SUPERFAMILY SSF53756 3 367 1.1E-43 T 28-03-2018 CWM22_RS07805 5852cc21793e4148ba6d3206947119d6 417 Gene3D G3DSA:3.40.50.2000 1 195 6.2E-7 T 28-03-2018 CWM22_RS10230 4b0306273c00a77325748df63cccd14a 272 Gene3D G3DSA:1.20.1510.10 2 196 4.9E-43 T 28-03-2018 CWM22_RS10230 4b0306273c00a77325748df63cccd14a 272 SUPERFAMILY SSF161111 5 197 3.4E-45 T 28-03-2018 CWM22_RS10230 4b0306273c00a77325748df63cccd14a 272 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 4 270 2.8E-55 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWM22_RS10230 4b0306273c00a77325748df63cccd14a 272 Pfam PF01545 Cation efflux family 8 196 4.6E-39 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWM22_RS03330 0537750239c329de0a2e95d65078c929 117 Pfam PF10694 Protein of unknown function (DUF2500) 17 115 5.2E-26 T 28-03-2018 IPR019635 Protein of unknown function DUF2500 CWM22_RS05820 07de68a168247a23c168d18397a467bb 121 Pfam PF05713 Bacterial mobilisation protein (MobC) 62 104 4.4E-10 T 28-03-2018 IPR008687 Bacterial mobilisation CWM22_RS03350 4add4dec97aa1b8004cf4e1effc75c00 306 Gene3D G3DSA:1.10.3720.10 20 305 1.6E-36 T 28-03-2018 CWM22_RS03350 4add4dec97aa1b8004cf4e1effc75c00 306 SUPERFAMILY SSF161098 64 290 6.93E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS03350 4add4dec97aa1b8004cf4e1effc75c00 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 300 2.4E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS08405 ac96ccda205968dc7de1157aa468f9a2 161 Pfam PF04525 LURP-one-related 4 148 6.9E-8 T 28-03-2018 IPR007612 LURP1-related protein domain CWM22_RS08405 ac96ccda205968dc7de1157aa468f9a2 161 SUPERFAMILY SSF54518 3 153 1.02E-30 T 28-03-2018 IPR025659 Tubby C-terminal-like domain CWM22_RS00750 59c919b753a75cb9b3a2917d15258d80 503 Pfam PF01719 Plasmid replication protein 107 197 7.4E-12 T 28-03-2018 IPR002631 Plasmid replication protein GO:0003677|GO:0003916|GO:0005727|GO:0006260 CWM22_RS00750 59c919b753a75cb9b3a2917d15258d80 503 SUPERFAMILY SSF52540 251 423 1.42E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00750 59c919b753a75cb9b3a2917d15258d80 503 Gene3D G3DSA:3.40.50.300 231 466 6.7E-12 T 28-03-2018 CWM22_RS06750 13c83bf01a64addd06f8edcd15e91a29 134 Gene3D G3DSA:2.40.128.50 29 134 1.3E-5 T 28-03-2018 IPR027279 D-aminopeptidase/lipoprotein domain CWM22_RS06090 fb4bac7d738a9df83f44826070deb4e5 102 SUPERFAMILY SSF50249 6 84 8.91E-6 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS06090 fb4bac7d738a9df83f44826070deb4e5 102 Gene3D G3DSA:2.40.50.140 2 100 3.5E-8 T 28-03-2018 CWM22_RS00465 a29a5e6b5a575cf1d8cb90b05f30f864 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 9.9E-36 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CWM22_RS00465 a29a5e6b5a575cf1d8cb90b05f30f864 88 Hamap MF_01507 UPF0297 protein . 1 84 26.848 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CWM22_RS00465 a29a5e6b5a575cf1d8cb90b05f30f864 88 PIRSF PIRSF037258 1 87 8.9E-43 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CWM22_RS02840 96c342d65db57069e8b9bcc8d1895e24 229 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 3.1E-14 T 28-03-2018 IPR019933 DivIVA domain CWM22_RS02840 96c342d65db57069e8b9bcc8d1895e24 229 Pfam PF05103 DivIVA protein 3 144 1.6E-37 T 28-03-2018 IPR007793 DivIVA family CWM22_RS07010 70cac4a5e7a737b1c18d3fd5b16eb6ee 360 Gene3D G3DSA:3.40.640.10 55 250 7.6E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS07010 70cac4a5e7a737b1c18d3fd5b16eb6ee 360 SUPERFAMILY SSF53383 27 357 2.5E-61 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS07010 70cac4a5e7a737b1c18d3fd5b16eb6ee 360 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CWM22_RS07010 70cac4a5e7a737b1c18d3fd5b16eb6ee 360 Gene3D G3DSA:3.90.1150.10 251 352 3.1E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS07010 70cac4a5e7a737b1c18d3fd5b16eb6ee 360 Pfam PF00155 Aminotransferase class I and II 46 348 5.3E-41 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWM22_RS07385 8154f00bbc756856e6bbe3df8dd6c53d 83 Pfam PF04531 Bacteriophage holin 5 71 5.2E-9 T 28-03-2018 IPR006485 Bacteriophage holin CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 Gene3D G3DSA:3.50.50.60 1 139 5.2E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 4.8E-19 T 28-03-2018 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 4.8E-19 T 28-03-2018 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 4.8E-19 T 28-03-2018 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.8E-19 T 28-03-2018 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 4.8E-19 T 28-03-2018 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 285 1.7E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 9.7E-22 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 9.7E-22 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 9.7E-22 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 9.7E-22 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 9.7E-22 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 SUPERFAMILY SSF51905 1 309 3.94E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 Gene3D G3DSA:3.40.50.720 142 320 7.4E-19 T 28-03-2018 CWM22_RS11975 3215b363ef91c63f9dff3f5a8ee51d90 322 Hamap MF_01685 Ferredoxin--NADP reductase. 4 322 40.936 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CWM22_RS07300 5161a1f05117ed59565adf3aa49a6b7e 167 Pfam PF06803 Protein of unknown function (DUF1232) 108 142 7.2E-11 T 28-03-2018 IPR010652 Protein of unknown function DUF1232 CWM22_RS06800 c44902789e4d5c1d2e3c4da22408a368 349 Pfam PF10117 McrBC 5-methylcytosine restriction system component 8 278 8.6E-32 T 28-03-2018 IPR019292 5-methylcytosine restriction system component CWM22_RS06800 c44902789e4d5c1d2e3c4da22408a368 349 PIRSF PIRSF003109 1 342 5.7E-55 T 28-03-2018 IPR014407 5-methylcytosine restriction system component, bacterial GO:0009307 CWM22_RS06905 6460351766a435e381da2f17a1cbc027 60 SUPERFAMILY SSF55331 2 57 2.26E-17 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CWM22_RS06905 6460351766a435e381da2f17a1cbc027 60 Gene3D G3DSA:3.30.429.10 1 57 1.5E-16 T 28-03-2018 CWM22_RS06905 6460351766a435e381da2f17a1cbc027 60 Pfam PF01361 Tautomerase enzyme 2 58 5.1E-24 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CWM22_RS06840 00131df4b2c103aa78d244e90c1a3982 117 Pfam PF08797 HIRAN domain 14 108 1.9E-13 T 28-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 CWM22_RS06840 00131df4b2c103aa78d244e90c1a3982 117 SMART SM00910 10 112 6.4E-22 T 28-03-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 CWM22_RS06455 c2772536eae3c04e68cc8dd5e47685d3 321 Pfam PF01076 Plasmid recombination enzyme 1 194 3.2E-59 T 28-03-2018 IPR001668 Plasmid recombination enzyme GO:0003677|GO:0005727|GO:0006310 CWM22_RS05735 c2772536eae3c04e68cc8dd5e47685d3 321 Pfam PF01076 Plasmid recombination enzyme 1 194 3.2E-59 T 28-03-2018 IPR001668 Plasmid recombination enzyme GO:0003677|GO:0005727|GO:0006310 CWM22_RS02150 f4f11133963c6178ec404c133b045c0b 224 Gene3D G3DSA:3.20.20.60 147 224 8.4E-11 T 28-03-2018 CWM22_RS02150 f4f11133963c6178ec404c133b045c0b 224 Gene3D G3DSA:3.20.20.60 34 146 4.4E-4 T 28-03-2018 CWM22_RS02150 f4f11133963c6178ec404c133b045c0b 224 SUPERFAMILY SSF51412 63 200 6.77E-14 T 28-03-2018 CWM22_RS04615 b61106aa9b93e00f79c2dd9bc083748a 193 SUPERFAMILY SSF140478 31 177 6.54E-48 T 28-03-2018 IPR023353 LemA-like domain CWM22_RS04615 b61106aa9b93e00f79c2dd9bc083748a 193 Gene3D G3DSA:1.20.1440.20 17 189 5.1E-51 T 28-03-2018 CWM22_RS04615 b61106aa9b93e00f79c2dd9bc083748a 193 Pfam PF04011 LemA family 10 188 2.6E-60 T 28-03-2018 IPR007156 LemA CWM22_RS03135 cb16a516758ceb28edef75e959dcc567 172 PIRSF PIRSF031501 1 172 2.8E-56 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CWM22_RS03135 cb16a516758ceb28edef75e959dcc567 172 Pfam PF06177 QueT transporter 13 166 3.7E-33 T 28-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CWM22_RS06010 1bd9edeaa7e849d1b2c599bb9bacaf32 162 Pfam PF03692 Putative zinc- or iron-chelating domain 50 137 3.5E-16 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein CWM22_RS11760 15dc2abd93357fb1e5f867d611892cdd 387 Gene3D G3DSA:1.20.1250.20 6 198 2.4E-23 T 28-03-2018 CWM22_RS11760 15dc2abd93357fb1e5f867d611892cdd 387 Pfam PF07690 Major Facilitator Superfamily 12 347 1.5E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWM22_RS11760 15dc2abd93357fb1e5f867d611892cdd 387 SUPERFAMILY SSF103473 9 380 3.14E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWM22_RS11760 15dc2abd93357fb1e5f867d611892cdd 387 Gene3D G3DSA:1.20.1250.20 203 383 4.8E-14 T 28-03-2018 CWM22_RS04800 7bcaead7cf7ba761c7c189a9cbd17d43 197 Pfam PF09335 SNARE associated Golgi protein 67 184 1.0E-17 T 28-03-2018 IPR032816 SNARE associated Golgi protein CWM22_RS01145 f8a31b103d8915feb7aecf5b2ea6dd5f 340 Pfam PF03601 Conserved hypothetical protein 698 8 318 1.3E-78 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CWM22_RS08975 40cc0a4e30ad33cf7f7c594673bd9650 272 SUPERFAMILY SSF52540 10 227 5.18E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS08975 40cc0a4e30ad33cf7f7c594673bd9650 272 Pfam PF13614 AAA domain 4 168 7.1E-16 T 28-03-2018 IPR025669 AAA domain CWM22_RS08975 40cc0a4e30ad33cf7f7c594673bd9650 272 Gene3D G3DSA:3.40.50.300 6 263 3.5E-23 T 28-03-2018 CWM22_RS04255 fca980650c7e54736b4ddffa36e1028a 574 Pfam PF06160 Septation ring formation regulator, EzrA 8 565 4.6E-172 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CWM22_RS04255 fca980650c7e54736b4ddffa36e1028a 574 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 6 568 22.153 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CWM22_RS04255 fca980650c7e54736b4ddffa36e1028a 574 Gene3D G3DSA:3.90.20.10 27 186 2.0E-4 T 28-03-2018 CWM22_RS08220 1b1f90bc1f8e60fea422cf1b58a17757 224 Gene3D G3DSA:1.20.1660.10 2 109 3.7E-8 T 28-03-2018 CWM22_RS08220 1b1f90bc1f8e60fea422cf1b58a17757 224 Pfam PF08713 DNA alkylation repair enzyme 8 186 2.4E-14 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CWM22_RS08220 1b1f90bc1f8e60fea422cf1b58a17757 224 SUPERFAMILY SSF48371 3 224 3.45E-51 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWM22_RS00200 dd42043982e203a1782665d08b9e1c01 413 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 332 356 1.5E-44 T 28-03-2018 IPR009148 Streptococcal non-M secreted SibA CWM22_RS00200 dd42043982e203a1782665d08b9e1c01 413 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 214 241 1.5E-44 T 28-03-2018 IPR009148 Streptococcal non-M secreted SibA CWM22_RS00200 dd42043982e203a1782665d08b9e1c01 413 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 307 329 1.5E-44 T 28-03-2018 IPR009148 Streptococcal non-M secreted SibA CWM22_RS00200 dd42043982e203a1782665d08b9e1c01 413 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 375 398 1.5E-44 T 28-03-2018 IPR009148 Streptococcal non-M secreted SibA CWM22_RS00200 dd42043982e203a1782665d08b9e1c01 413 Pfam PF05257 CHAP domain 304 382 4.6E-14 T 28-03-2018 IPR007921 CHAP domain CWM22_RS00200 dd42043982e203a1782665d08b9e1c01 413 SUPERFAMILY SSF54001 299 413 6.38E-25 T 28-03-2018 CWM22_RS00200 dd42043982e203a1782665d08b9e1c01 413 Gene3D G3DSA:1.20.5.400 27 98 7.4E-7 T 28-03-2018 CWM22_RS11065 1e7a0cc7107a329b801a07a6cf4e9abd 218 Gene3D G3DSA:1.10.1900.10 5 85 7.5E-5 T 28-03-2018 CWM22_RS11065 1e7a0cc7107a329b801a07a6cf4e9abd 218 Pfam PF06570 Protein of unknown function (DUF1129) 9 212 2.0E-75 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 CWM22_RS11065 1e7a0cc7107a329b801a07a6cf4e9abd 218 PIRSF PIRSF033111 1 218 1.1E-82 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 CWM22_RS00070 2a80dda9aaa0d11d97d4b200dd1a689a 180 Gene3D G3DSA:3.40.50.2020 1 180 1.1E-47 T 28-03-2018 CWM22_RS00070 2a80dda9aaa0d11d97d4b200dd1a689a 180 Pfam PF00156 Phosphoribosyl transferase domain 11 160 1.1E-27 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWM22_RS00070 2a80dda9aaa0d11d97d4b200dd1a689a 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 10 174 4.8E-64 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CWM22_RS00070 2a80dda9aaa0d11d97d4b200dd1a689a 180 SUPERFAMILY SSF53271 3 178 2.88E-56 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS11080 b536f7c22d765dd3c2e296f2b4f4d185 96 Gene3D G3DSA:3.30.70.60 1 96 4.7E-30 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CWM22_RS11080 b536f7c22d765dd3c2e296f2b4f4d185 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 96 21.826 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWM22_RS11080 b536f7c22d765dd3c2e296f2b4f4d185 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 95 2.0E-26 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11080 b536f7c22d765dd3c2e296f2b4f4d185 96 SUPERFAMILY SSF54995 1 95 2.75E-32 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS11080 b536f7c22d765dd3c2e296f2b4f4d185 96 Pfam PF01250 Ribosomal protein S6 3 93 1.1E-26 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWM22_RS13115 d14ce97958917ef86585e7d133f303ed 204 SMART SM00382 26 201 8.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS13115 d14ce97958917ef86585e7d133f303ed 204 Pfam PF00005 ABC transporter 17 151 4.4E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWM22_RS13115 d14ce97958917ef86585e7d133f303ed 204 Gene3D G3DSA:3.40.50.300 1 204 6.0E-37 T 28-03-2018 CWM22_RS13115 d14ce97958917ef86585e7d133f303ed 204 SUPERFAMILY SSF52540 13 201 7.07E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS13115 d14ce97958917ef86585e7d133f303ed 204 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWM22_RS05325 ef48f3358658f70388dc43004586cf2e 67 Pfam PF15507 Domain of unknown function (DUF4649) 2 67 3.3E-31 T 28-03-2018 IPR027879 Protein of unknown function DUF4649 CWM22_RS04420 422e2e7bbc2071fd2e1ae11df15bdfd8 332 Gene3D G3DSA:3.40.50.2000 75 313 7.1E-8 T 28-03-2018 CWM22_RS04420 422e2e7bbc2071fd2e1ae11df15bdfd8 332 PIRSF PIRSF007023 1 332 4.4E-96 T 28-03-2018 IPR016503 UDP-galactofuranosyltransferase GO:0016757 CWM22_RS04420 422e2e7bbc2071fd2e1ae11df15bdfd8 332 SUPERFAMILY SSF53756 82 145 2.2E-5 T 28-03-2018 CWM22_RS05590 4c039c9763a25eaa8d632530001813ae 320 Gene3D G3DSA:3.40.50.300 31 304 7.8E-8 T 28-03-2018 CWM22_RS05590 4c039c9763a25eaa8d632530001813ae 320 SUPERFAMILY SSF52540 27 302 3.19E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS09825 81682248c4873328b9309510fa0f35d1 224 Pfam PF13643 Domain of unknown function (DUF4145) 120 194 2.6E-5 T 28-03-2018 IPR025285 Domain of unknown function DUF4145 CWM22_RS09480 f8d16b06603a82bd3bd7cbd7128c100c 296 Gene3D G3DSA:3.30.420.40 1 118 6.4E-25 T 28-03-2018 CWM22_RS09480 f8d16b06603a82bd3bd7cbd7128c100c 296 Gene3D G3DSA:3.30.420.40 119 293 6.8E-43 T 28-03-2018 CWM22_RS09480 f8d16b06603a82bd3bd7cbd7128c100c 296 Pfam PF00480 ROK family 4 291 2.6E-53 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWM22_RS09480 f8d16b06603a82bd3bd7cbd7128c100c 296 SUPERFAMILY SSF53067 1 291 1.13E-60 T 28-03-2018 CWM22_RS06115 1775299b91f9f5b734f3881a95b9f0f6 1070 SUPERFAMILY SSF54001 949 1061 3.33E-14 T 28-03-2018 CWM22_RS06115 1775299b91f9f5b734f3881a95b9f0f6 1070 Pfam PF05257 CHAP domain 956 1043 5.1E-14 T 28-03-2018 IPR007921 CHAP domain CWM22_RS01800 d1b4656aebc32662ea7f2de6afd5a1a1 425 Pfam PF01554 MatE 226 385 2.5E-18 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS01800 d1b4656aebc32662ea7f2de6afd5a1a1 425 Pfam PF01554 MatE 14 172 2.6E-25 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS01800 d1b4656aebc32662ea7f2de6afd5a1a1 425 PIRSF PIRSF006603 2 425 2.5E-74 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS01800 d1b4656aebc32662ea7f2de6afd5a1a1 425 TIGRFAM TIGR00797 matE: MATE efflux family protein 14 398 8.0E-53 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CWM22_RS04930 2ae2535e936417650217120dce37244a 284 Pfam PF13349 Putative adhesin 55 283 3.8E-17 T 28-03-2018 IPR025164 Putative adhesin CWM22_RS04600 fd6ee07ee4fcac10d7da4814dbc396f9 152 Pfam PF00583 Acetyltransferase (GNAT) family 25 133 5.2E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS04600 fd6ee07ee4fcac10d7da4814dbc396f9 152 SUPERFAMILY SSF55729 1 143 8.78E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS04600 fd6ee07ee4fcac10d7da4814dbc396f9 152 Gene3D G3DSA:3.40.630.30 1 148 2.3E-22 T 28-03-2018 CWM22_RS04945 63267b810b0cc1a25e2ae7cd6d35783a 105 SUPERFAMILY SSF46785 10 101 8.77E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS04945 63267b810b0cc1a25e2ae7cd6d35783a 105 Pfam PF03551 Transcriptional regulator PadR-like family 14 81 3.5E-21 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWM22_RS04945 63267b810b0cc1a25e2ae7cd6d35783a 105 Gene3D G3DSA:1.10.10.10 5 93 8.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS10620 dd5c30f615aedcedf72b9413b5c346ff 177 Pfam PF11683 Protein of unknown function (DUF3278) 11 79 1.6E-12 T 28-03-2018 IPR021697 Protein of unknown function DUF3278 CWM22_RS00270 1ec9be20263986f7cb49d855b5eb4af5 240 Pfam PF06182 ABC-2 family transporter protein 28 222 2.6E-10 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 Gene3D G3DSA:2.20.230.10 422 500 5.7E-12 T 28-03-2018 CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 Gene3D G3DSA:2.20.230.10 585 663 1.2E-12 T 28-03-2018 CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 Gene3D G3DSA:2.20.230.10 664 744 3.8E-16 T 28-03-2018 CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 Gene3D G3DSA:2.20.230.10 501 584 4.9E-11 T 28-03-2018 CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 Pfam PF07501 G5 domain 587 659 5.5E-11 T 28-03-2018 IPR011098 G5 domain CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 Pfam PF07501 G5 domain 426 499 5.0E-10 T 28-03-2018 IPR011098 G5 domain CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 Pfam PF07501 G5 domain 665 738 1.2E-13 T 28-03-2018 IPR011098 G5 domain CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 Pfam PF07501 G5 domain 504 579 5.3E-6 T 28-03-2018 IPR011098 G5 domain CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 SMART SM01208 661 739 9.9E-16 T 28-03-2018 IPR011098 G5 domain CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 SMART SM01208 421 500 1.1E-10 T 28-03-2018 IPR011098 G5 domain CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 SMART SM01208 501 580 2.3E-4 T 28-03-2018 IPR011098 G5 domain CWM22_RS06075 ea3d248ce3b00f26234e38e3a942eaf3 864 SMART SM01208 581 660 1.1E-11 T 28-03-2018 IPR011098 G5 domain CWM22_RS07390 313b757adf594ae5b474e80a584c1ab1 254 Pfam PF02517 CAAX protease self-immunity 159 242 2.9E-7 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS09735 91055b6b462f906c869f9fc2596ce08f 188 Gene3D G3DSA:1.10.443.10 5 187 1.2E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS09735 91055b6b462f906c869f9fc2596ce08f 188 SUPERFAMILY SSF56349 6 186 8.24E-38 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWM22_RS09735 91055b6b462f906c869f9fc2596ce08f 188 Pfam PF00589 Phage integrase family 11 172 1.3E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWM22_RS13410 1b76890bade91a059f61454efe160be2 227 Pfam PF06912 Protein of unknown function (DUF1275) 15 204 6.8E-31 T 28-03-2018 IPR010699 Protein of unknown function DUF1275 CWM22_RS00890 eab20bf35027d07cd015576ab1598afb 316 SMART SM00382 130 259 0.0079 T 28-03-2018 IPR003593 AAA+ ATPase domain CWM22_RS00890 eab20bf35027d07cd015576ab1598afb 316 SUPERFAMILY SSF52540 2 267 3.74E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS00890 eab20bf35027d07cd015576ab1598afb 316 Gene3D G3DSA:3.40.50.300 122 307 5.8E-29 T 28-03-2018 CWM22_RS00890 eab20bf35027d07cd015576ab1598afb 316 Pfam PF00437 Type II/IV secretion system protein 9 265 1.2E-47 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWM22_RS00890 eab20bf35027d07cd015576ab1598afb 316 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 196 210 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWM22_RS00890 eab20bf35027d07cd015576ab1598afb 316 Gene3D G3DSA:3.30.450.90 1 108 1.2E-22 T 28-03-2018 CWM22_RS05505 f73cf412020d42bfabdde0a569236413 77 Gene3D G3DSA:1.10.260.40 1 76 8.8E-5 T 28-03-2018 CWM22_RS06305 f73cf412020d42bfabdde0a569236413 77 Gene3D G3DSA:1.10.260.40 1 76 8.8E-5 T 28-03-2018 CWM22_RS04080 29af8ecac5cd3f3c873af53d80486b13 68 Pfam PF14206 Cysteine-rich CPCC 18 62 3.6E-8 T 28-03-2018 IPR025983 Cysteine-rich CPCC domain CWM22_RS06575 ae9ec47a608eddff1ee94f56f60918a2 51 Pfam PF04604 Type-A lantibiotic 1 50 3.1E-28 T 28-03-2018 IPR007682 Lantibiotic, type A, Lactobacillales-type GO:0005576|GO:0042742 CWM22_RS07815 e1080beaf81dc3edcfb8774320fa332d 326 Gene3D G3DSA:3.90.550.10 1 293 7.0E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07815 e1080beaf81dc3edcfb8774320fa332d 326 Pfam PF00535 Glycosyl transferase family 2 4 124 5.1E-34 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS07815 e1080beaf81dc3edcfb8774320fa332d 326 SUPERFAMILY SSF53448 2 228 1.13E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS08650 c208ef9d847510c9952c511bf1f83673 315 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 292 1.9E-43 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWM22_RS08650 c208ef9d847510c9952c511bf1f83673 315 Gene3D G3DSA:1.10.3470.10 4 298 6.8E-33 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS08590 78f1b6f23174e2351b51886bd934f1b7 294 Gene3D G3DSA:3.40.50.300 13 164 1.2E-23 T 28-03-2018 CWM22_RS08590 78f1b6f23174e2351b51886bd934f1b7 294 Pfam PF13177 DNA polymerase III, delta subunit 10 165 1.5E-53 T 28-03-2018 CWM22_RS08590 78f1b6f23174e2351b51886bd934f1b7 294 SUPERFAMILY SSF52540 10 176 9.04E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS04550 b3daed40ac7492d1496cb648494712ba 261 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 19 213 2.0E-43 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CWM22_RS04550 b3daed40ac7492d1496cb648494712ba 261 Gene3D G3DSA:3.40.50.880 22 235 5.0E-17 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS04550 b3daed40ac7492d1496cb648494712ba 261 SUPERFAMILY SSF52317 33 206 5.02E-24 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWM22_RS12185 3b4bcd9863962ef3c7b47eb1d83b920d 109 Gene3D G3DSA:3.30.2310.20 5 108 3.9E-4 T 28-03-2018 CWM22_RS12185 3b4bcd9863962ef3c7b47eb1d83b920d 109 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 96 1.4E-7 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CWM22_RS06035 dc7bf0d4c16f978b018b6e48c5c160d1 183 Pfam PF08876 Domain of unknown function (DUF1836) 6 140 5.5E-38 T 28-03-2018 IPR014975 Protein of unknown function DUF1836 CWM22_RS07835 5f078d6d98c63f2de4b39fef76553131 574 Pfam PF05045 Rhamnan synthesis protein F 34 491 5.2E-69 T 28-03-2018 IPR007739 Rhamnan synthesis F CWM22_RS01925 c67396a9e958300c7623b8bc56b2c533 71 Gene3D G3DSA:1.10.260.40 2 71 3.1E-10 T 28-03-2018 CWM22_RS01925 c67396a9e958300c7623b8bc56b2c533 71 SMART SM00530 7 63 0.0031 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS01925 c67396a9e958300c7623b8bc56b2c533 71 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 67 7.7E-24 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWM22_RS01925 c67396a9e958300c7623b8bc56b2c533 71 SUPERFAMILY SSF47413 3 68 1.52E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWM22_RS04105 2c19d17cf7b741a5ed61f39614ac69ef 109 Pfam PF05135 Phage gp6-like head-tail connector protein 2 81 2.4E-8 T 28-03-2018 IPR021146 Phage gp6-like head-tail connector protein CWM22_RS09785 946ea07063e0d2f60ecc8b497a5b1397 71 SUPERFAMILY SSF89447 3 53 5.76E-8 T 28-03-2018 CWM22_RS09785 946ea07063e0d2f60ecc8b497a5b1397 71 SMART SM00966 7 49 1.8E-4 T 28-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CWM22_RS09785 946ea07063e0d2f60ecc8b497a5b1397 71 Gene3D G3DSA:2.10.260.10 4 43 6.8E-10 T 28-03-2018 CWM22_RS03210 77f0c502ac0d8e2552d7a12f50dd539b 253 SUPERFAMILY SSF54427 135 240 4.39E-17 T 28-03-2018 IPR032710 NTF2-like domain CWM22_RS03210 77f0c502ac0d8e2552d7a12f50dd539b 253 Gene3D G3DSA:3.10.450.50 4 125 6.9E-16 T 28-03-2018 CWM22_RS03210 77f0c502ac0d8e2552d7a12f50dd539b 253 Gene3D G3DSA:3.10.450.50 131 251 7.7E-12 T 28-03-2018 CWM22_RS03210 77f0c502ac0d8e2552d7a12f50dd539b 253 Pfam PF12680 SnoaL-like domain 19 107 3.4E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CWM22_RS03210 77f0c502ac0d8e2552d7a12f50dd539b 253 Pfam PF12680 SnoaL-like domain 143 234 2.9E-6 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CWM22_RS03210 77f0c502ac0d8e2552d7a12f50dd539b 253 SUPERFAMILY SSF54427 16 115 2.04E-18 T 28-03-2018 IPR032710 NTF2-like domain CWM22_RS05440 5ed505a98f3822a9a5f2fdfe1f7d6624 163 SUPERFAMILY SSF55729 27 154 1.49E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS05440 5ed505a98f3822a9a5f2fdfe1f7d6624 163 Pfam PF00583 Acetyltransferase (GNAT) family 47 147 5.1E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS05440 5ed505a98f3822a9a5f2fdfe1f7d6624 163 Gene3D G3DSA:3.40.630.30 4 161 1.5E-15 T 28-03-2018 CWM22_RS07820 2bfe2af5f21f7439ab988514f86e6e08 329 Pfam PF01501 Glycosyl transferase family 8 2 256 7.1E-40 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 CWM22_RS07820 2bfe2af5f21f7439ab988514f86e6e08 329 SUPERFAMILY SSF53448 1 281 5.06E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07820 2bfe2af5f21f7439ab988514f86e6e08 329 Gene3D G3DSA:3.90.550.10 1 285 1.7E-49 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04450 a89ea37d0b9b1c5d14c9eb2e3daff033 297 Pfam PF00535 Glycosyl transferase family 2 9 129 4.3E-35 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWM22_RS04450 a89ea37d0b9b1c5d14c9eb2e3daff033 297 SUPERFAMILY SSF53448 6 231 1.9E-55 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS04450 a89ea37d0b9b1c5d14c9eb2e3daff033 297 Gene3D G3DSA:3.90.550.10 6 234 4.0E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWM22_RS07230 82a83ef5be947d25329a431023c03a69 441 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 9 419 3.0E-112 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWM22_RS07230 82a83ef5be947d25329a431023c03a69 441 Pfam PF05525 Branched-chain amino acid transport protein 3 432 9.5E-137 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWM22_RS11040 a996d3218e4fdc4781ab089e3b2fc516 115 Gene3D G3DSA:2.40.128.50 22 114 7.8E-8 T 28-03-2018 IPR027279 D-aminopeptidase/lipoprotein domain CWM22_RS06780 29ff3801d1900ce342c4ec085e47fad0 174 Gene3D G3DSA:1.20.1170.10 29 159 6.4E-5 T 28-03-2018 CWM22_RS09910 a4b75ec380dd4184e6f80274b923a1c4 162 Pfam PF04892 VanZ like family 11 130 5.3E-19 T 28-03-2018 IPR006976 VanZ-like CWM22_RS04400 727cd2d5d4ff8d9f5c0fa01de1965aa1 90 Pfam PF04531 Bacteriophage holin 3 61 2.3E-7 T 28-03-2018 IPR006485 Bacteriophage holin CWM22_RS12760 a349e8851721e145a9a1de792402ec83 237 Pfam PF04474 Protein of unknown function (DUF554) 4 235 4.6E-72 T 28-03-2018 IPR007563 Protein of unknown function DUF554 CWM22_RS03535 0920dea0d928e569d33691f9c81e0c96 229 Pfam PF02706 Chain length determinant protein 10 101 1.1E-24 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CWM22_RS03535 0920dea0d928e569d33691f9c81e0c96 229 Gene3D G3DSA:3.30.1890.10 40 167 1.8E-10 T 28-03-2018 CWM22_RS06195 3962768410e12deca9b0433bf7070bf8 431 Pfam PF03432 Relaxase/Mobilisation nuclease domain 11 248 1.1E-42 T 28-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 CWM22_RS03890 6b6905688f8457ab1349acbaa6ae033e 144 SUPERFAMILY SSF50118 2 97 9.16E-10 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWM22_RS03890 6b6905688f8457ab1349acbaa6ae033e 144 Gene3D G3DSA:2.30.30.110 1 143 4.0E-27 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWM22_RS03890 6b6905688f8457ab1349acbaa6ae033e 144 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 99 3.8E-11 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CWM22_RS06585 bbf3818d45d87fc1f02fe09edd20d0ed 55 Pfam PF04604 Type-A lantibiotic 3 55 4.4E-21 T 28-03-2018 IPR007682 Lantibiotic, type A, Lactobacillales-type GO:0005576|GO:0042742 CWM22_RS04410 fc7895657c24301b3b16651e4c467537 294 SUPERFAMILY SSF51161 48 149 7.07E-33 T 28-03-2018 IPR011004 Trimeric LpxA-like CWM22_RS04410 fc7895657c24301b3b16651e4c467537 294 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 139 3.3E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CWM22_RS04410 fc7895657c24301b3b16651e4c467537 294 Gene3D G3DSA:2.160.10.10 12 172 2.0E-32 T 28-03-2018 CWM22_RS12570 f839d6fd3d5aec492b027ba224cbec83 103 SUPERFAMILY SSF52794 1 102 1.83E-36 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS12570 f839d6fd3d5aec492b027ba224cbec83 103 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 95 6.9E-25 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWM22_RS12570 f839d6fd3d5aec492b027ba224cbec83 103 Gene3D G3DSA:3.40.50.2300 2 103 1.1E-34 T 28-03-2018 CWM22_RS05405 98add9b780ad86fee1dfc8eb6e0b975e 383 SUPERFAMILY SSF56796 2 381 1.7E-120 T 28-03-2018 CWM22_RS05405 98add9b780ad86fee1dfc8eb6e0b975e 383 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 171 199 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWM22_RS05405 98add9b780ad86fee1dfc8eb6e0b975e 383 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 374 2.6E-115 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CWM22_RS05405 98add9b780ad86fee1dfc8eb6e0b975e 383 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 258 278 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CWM22_RS05405 98add9b780ad86fee1dfc8eb6e0b975e 383 Gene3D G3DSA:3.40.50.1970 7 180 5.3E-43 T 28-03-2018 CWM22_RS05405 98add9b780ad86fee1dfc8eb6e0b975e 383 Gene3D G3DSA:1.20.1090.10 182 383 8.5E-63 T 28-03-2018 CWM22_RS12565 3379afb4509a42e010e07a0673fbd1b5 110 SUPERFAMILY SSF46973 2 102 2.75E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS12565 3379afb4509a42e010e07a0673fbd1b5 110 PIRSF PIRSF000699 1 108 2.1E-37 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS12565 3379afb4509a42e010e07a0673fbd1b5 110 Gene3D G3DSA:1.20.58.80 4 102 3.7E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS12565 3379afb4509a42e010e07a0673fbd1b5 110 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 9 101 1.9E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWM22_RS09860 5cb72487f8af0bc5eb73ae91849ae699 281 Pfam PF02498 BRO family, N-terminal domain 27 109 1.1E-5 T 28-03-2018 IPR003497 BRO N-terminal domain CWM22_RS10685 42cb18ae25442ed395ec5f708f798ca1 449 Pfam PF02386 Cation transport protein 37 428 3.5E-53 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CWM22_RS06200 cb485ea57a37097e2b0f2ab0f4d81657 117 Pfam PF05713 Bacterial mobilisation protein (MobC) 62 101 3.2E-6 T 28-03-2018 IPR008687 Bacterial mobilisation CWM22_RS01200 3aace392aff1e25f4e4ca9db3f4aeb97 282 SUPERFAMILY SSF52518 5 259 1.65E-79 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWM22_RS01200 3aace392aff1e25f4e4ca9db3f4aeb97 282 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 9 255 3.4E-46 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWM22_RS01200 3aace392aff1e25f4e4ca9db3f4aeb97 282 Gene3D G3DSA:3.40.50.970 1 279 6.4E-66 T 28-03-2018 CWM22_RS01225 0ab8dc80e3b9555b2996d7fc94f6b0f1 387 Pfam PF13936 Helix-turn-helix domain 2 45 5.9E-16 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CWM22_RS01225 0ab8dc80e3b9555b2996d7fc94f6b0f1 387 Gene3D G3DSA:1.10.10.60 2 47 5.7E-9 T 28-03-2018 CWM22_RS01225 0ab8dc80e3b9555b2996d7fc94f6b0f1 387 SUPERFAMILY SSF53098 206 356 2.85E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS01225 0ab8dc80e3b9555b2996d7fc94f6b0f1 387 Gene3D G3DSA:3.30.420.10 202 360 2.1E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWM22_RS03975 6cf7c90a511052972ffc6c4b4b1a2495 268 SMART SM00943 8 160 6.6E-38 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CWM22_RS03975 6cf7c90a511052972ffc6c4b4b1a2495 268 SUPERFAMILY SSF56747 2 170 3.07E-49 T 28-03-2018 CWM22_RS03975 6cf7c90a511052972ffc6c4b4b1a2495 268 SMART SM00942 193 258 9.2E-19 T 28-03-2018 IPR014820 Primase, C-terminal 1 CWM22_RS03975 6cf7c90a511052972ffc6c4b4b1a2495 268 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 8 157 1.0E-27 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CWM22_RS03975 6cf7c90a511052972ffc6c4b4b1a2495 268 Pfam PF08708 Primase C terminal 1 (PriCT-1) 200 257 3.4E-11 T 28-03-2018 IPR014820 Primase, C-terminal 1 CWM22_RS02225 45e8e46d8be870982444db8621e3a4ab 225 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 9 218 1.6E-33 T 28-03-2018 IPR027607 SEC10/PgrA surface exclusion domain CWM22_RS00435 f163bee222a87336e806ca9801a8b6cd 215 Pfam PF02517 CAAX protease self-immunity 121 211 2.0E-19 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS04745 64065f379aaacb68412f356d97dad2d4 205 Pfam PF00293 NUDIX domain 74 178 7.9E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWM22_RS04745 64065f379aaacb68412f356d97dad2d4 205 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 4 59 1.3E-27 T 28-03-2018 CWM22_RS04745 64065f379aaacb68412f356d97dad2d4 205 SUPERFAMILY SSF55811 58 201 1.14E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWM22_RS04745 64065f379aaacb68412f356d97dad2d4 205 Gene3D G3DSA:3.90.79.10 58 204 1.3E-21 T 28-03-2018 CWM22_RS10645 09151db39f7c54ec77a37e3a9ecefe45 142 Pfam PF07009 NusG domain II 17 127 1.9E-28 T 28-03-2018 IPR024045 NusG, domain 2 CWM22_RS10645 09151db39f7c54ec77a37e3a9ecefe45 142 Gene3D G3DSA:2.60.320.10 30 137 1.6E-27 T 28-03-2018 CWM22_RS09740 f24f6a9e07968194d5a94bef05083523 145 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 4 133 1.2E-27 T 28-03-2018 IPR006524 Transcription activator, ArpU family CWM22_RS03920 ad5b8d34b599b9de11ecee494fd4fc55 63 Gene3D G3DSA:1.10.260.40 3 59 3.4E-5 T 28-03-2018 CWM22_RS11860 e6d682460107c72741b000008642fa37 124 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 4 120 1.0E-36 T 28-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain CWM22_RS11860 e6d682460107c72741b000008642fa37 124 Pfam PF03610 PTS system fructose IIA component 5 113 7.5E-22 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWM22_RS11860 e6d682460107c72741b000008642fa37 124 Gene3D G3DSA:3.40.50.510 1 123 5.6E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWM22_RS11860 e6d682460107c72741b000008642fa37 124 SUPERFAMILY SSF53062 3 120 2.62E-32 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWM22_RS13225 16116473b336e690afca3a22c1150e17 187 SUPERFAMILY SSF52833 8 186 3.57E-35 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS13225 16116473b336e690afca3a22c1150e17 187 Pfam PF08534 Redoxin 38 175 7.2E-22 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CWM22_RS13225 16116473b336e690afca3a22c1150e17 187 Gene3D G3DSA:3.40.30.10 27 187 3.4E-35 T 28-03-2018 CWM22_RS03545 5bed8a0bb33bbc55ec86430baa1dd283 243 Gene3D G3DSA:3.20.20.140 1 243 7.3E-27 T 28-03-2018 CWM22_RS03545 5bed8a0bb33bbc55ec86430baa1dd283 243 SUPERFAMILY SSF51556 1 238 7.48E-19 T 28-03-2018 IPR032466 Metal-dependent hydrolase CWM22_RS03545 5bed8a0bb33bbc55ec86430baa1dd283 243 PIRSF PIRSF016557 1 243 1.3E-86 T 28-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 CWM22_RS13230 85c72f92caa5e475e58026b890bdd590 231 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 12 219 7.6E-52 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CWM22_RS03270 b01930caf28c6ed3ad73a72ec6c91edc 78 Pfam PF11195 Protein of unknown function (DUF2829) 2 76 2.2E-21 T 28-03-2018 IPR021361 Protein of unknown function DUF2829 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 191 2.9E-46 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 SUPERFAMILY SSF52540 3 197 2.1E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 PRINTS PR00988 Uridine kinase signature 5 22 4.5E-39 T 28-03-2018 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 PRINTS PR00988 Uridine kinase signature 35 46 4.5E-39 T 28-03-2018 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 PRINTS PR00988 Uridine kinase signature 150 161 4.5E-39 T 28-03-2018 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 PRINTS PR00988 Uridine kinase signature 136 146 4.5E-39 T 28-03-2018 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 PRINTS PR00988 Uridine kinase signature 80 95 4.5E-39 T 28-03-2018 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 PRINTS PR00988 Uridine kinase signature 172 185 4.5E-39 T 28-03-2018 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 Gene3D G3DSA:3.40.50.300 1 209 3.9E-60 T 28-03-2018 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 TIGRFAM TIGR00235 udk: uridine kinase 3 205 1.4E-86 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 CWM22_RS03045 2bfbe519ae5601046caf25c2ef1bcb12 209 Hamap MF_00551 Uridine kinase [udk]. 2 206 42.311 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 CWM22_RS03320 02f47d7b742b0f974df593a362bc623a 181 Pfam PF07155 ECF-type riboflavin transporter, S component 6 169 4.3E-17 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CWM22_RS04650 5b1b60cf792e9635c29ac1d7e00a3cf4 48 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 2 42 1.2E-6 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) CWM22_RS04935 860d5de12699ab5746d5b78a6c3f4e69 192 Pfam PF08006 Protein of unknown function (DUF1700) 1 165 1.3E-19 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 CWM22_RS02020 d62afbaa676e97e62f0ce57df916934b 339 SUPERFAMILY SSF53474 74 335 1.62E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS02020 d62afbaa676e97e62f0ce57df916934b 339 Gene3D G3DSA:3.40.50.1820 43 245 9.8E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWM22_RS02020 d62afbaa676e97e62f0ce57df916934b 339 Pfam PF07859 alpha/beta hydrolase fold 98 297 1.7E-18 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CWM22_RS02405 99a9dbdceaf3599f2c44f8bccc225c4e 277 Pfam PF02361 Cobalt transport protein 15 236 8.5E-26 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CWM22_RS02115 4b7e5f78eef92d70a84d875181330479 172 Gene3D G3DSA:1.10.3420.10 2 171 3.7E-41 T 28-03-2018 CWM22_RS02115 4b7e5f78eef92d70a84d875181330479 172 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 12 124 1.6E-26 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CWM22_RS11300 fc5dbbe341b46cc93106d12a1a42b6bd 346 Pfam PF05975 Bacterial ABC transporter protein EcsB 2 158 2.4E-31 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CWM22_RS11300 fc5dbbe341b46cc93106d12a1a42b6bd 346 Pfam PF05975 Bacterial ABC transporter protein EcsB 155 329 1.1E-42 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CWM22_RS11300 fc5dbbe341b46cc93106d12a1a42b6bd 346 PIRSF PIRSF037259 151 346 8.5E-59 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CWM22_RS11300 fc5dbbe341b46cc93106d12a1a42b6bd 346 PIRSF PIRSF037259 1 158 2.1E-43 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CWM22_RS02015 1c017c216c568e8cdac2868d6ece5809 372 Pfam PF03283 Pectinacetylesterase 66 217 3.4E-12 T 28-03-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 CWM22_RS09495 e22ba84de05c8da7935695afb9c414f3 151 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 150 2.4E-28 T 28-03-2018 IPR004375 YhcH/YjgK/YiaL family CWM22_RS09495 e22ba84de05c8da7935695afb9c414f3 151 Gene3D G3DSA:2.60.120.370 1 150 1.7E-37 T 28-03-2018 IPR004375 YhcH/YjgK/YiaL family CWM22_RS09495 e22ba84de05c8da7935695afb9c414f3 151 Pfam PF04074 Domain of unknown function (DUF386) 1 147 6.6E-34 T 28-03-2018 IPR004375 YhcH/YjgK/YiaL family CWM22_RS09495 e22ba84de05c8da7935695afb9c414f3 151 SUPERFAMILY SSF51197 1 149 3.02E-37 T 28-03-2018 CWM22_RS09730 b270db6d5d151b7b17146a320c07e77e 112 Pfam PF01844 HNH endonuclease 30 83 2.6E-12 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CWM22_RS09730 b270db6d5d151b7b17146a320c07e77e 112 Gene3D G3DSA:3.40.1800.10 11 94 1.7E-12 T 28-03-2018 CWM22_RS09730 b270db6d5d151b7b17146a320c07e77e 112 SMART SM00507 19 78 1.1E-8 T 28-03-2018 IPR003615 HNH nuclease CWM22_RS05400 1340dc14590ba419d633a789655940ec 106 Gene3D G3DSA:2.20.25.10 33 101 6.2E-11 T 28-03-2018 CWM22_RS00050 ac9787e9252c1d94df6bd7150edece87 122 Pfam PF04977 Septum formation initiator 43 118 8.6E-17 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CWM22_RS13235 75a925f6c5780690da6466d241da58a0 83 Gene3D G3DSA:2.30.30.100 8 81 3.5E-27 T 28-03-2018 CWM22_RS13235 75a925f6c5780690da6466d241da58a0 83 Pfam PF06257 Biofilm formation stimulator VEG 10 80 4.6E-26 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CWM22_RS13235 75a925f6c5780690da6466d241da58a0 83 PIRSF PIRSF037257 1 83 2.2E-28 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CWM22_RS07185 ef22089012fa78ffdea655a3ee6c1830 173 Pfam PF00156 Phosphoribosyl transferase domain 4 144 1.7E-24 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWM22_RS07185 ef22089012fa78ffdea655a3ee6c1830 173 Gene3D G3DSA:3.40.50.2020 1 173 2.5E-34 T 28-03-2018 CWM22_RS07185 ef22089012fa78ffdea655a3ee6c1830 173 SUPERFAMILY SSF53271 5 165 3.67E-37 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS07185 ef22089012fa78ffdea655a3ee6c1830 173 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 171 35.951 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CWM22_RS02675 4ee0154c2d13a52c8444c0f08a70e49f 272 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 7 266 1.7E-80 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CWM22_RS06860 ecdf86d9d2f531161a6ce1db7ab0d3b6 324 Pfam PF04245 37-kD nucleoid-associated bacterial protein 9 320 3.0E-35 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 CWM22_RS03215 bed8f58cecd4919485412f406243396b 374 Pfam PF00155 Aminotransferase class I and II 52 362 1.4E-44 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWM22_RS03215 bed8f58cecd4919485412f406243396b 374 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 218 231 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CWM22_RS03215 bed8f58cecd4919485412f406243396b 374 Gene3D G3DSA:3.40.640.10 46 281 1.3E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWM22_RS03215 bed8f58cecd4919485412f406243396b 374 Gene3D G3DSA:3.90.1150.10 282 371 4.6E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWM22_RS03215 bed8f58cecd4919485412f406243396b 374 SUPERFAMILY SSF53383 54 369 1.97E-81 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWM22_RS04470 c74cbf6962fdcc2f37e8b1a092ec6705 342 TIGRFAM TIGR03711 acc_sec_asp3: accessory Sec system protein Asp3 31 161 3.2E-46 T 28-03-2018 IPR022259 Accessory Sec system protein Asp3 GO:0015031 CWM22_RS04470 c74cbf6962fdcc2f37e8b1a092ec6705 342 Pfam PF15432 Accessory Sec secretory system ASP3 42 164 9.3E-44 T 28-03-2018 IPR022259 Accessory Sec system protein Asp3 GO:0015031 CWM22_RS11545 436eb2a416e6428b7700eb41283a08c6 297 Gene3D G3DSA:3.20.20.70 173 285 0.0011 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS11545 436eb2a416e6428b7700eb41283a08c6 297 Gene3D G3DSA:3.20.20.70 18 172 0.0011 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWM22_RS11545 436eb2a416e6428b7700eb41283a08c6 297 SUPERFAMILY SSF51366 49 228 6.12E-6 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWM22_RS10445 7e13fc7eb6160d7246ade5781734b952 93 Pfam PF00708 Acylphosphatase 5 89 7.0E-20 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CWM22_RS10445 7e13fc7eb6160d7246ade5781734b952 93 SUPERFAMILY SSF54975 2 90 2.62E-20 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CWM22_RS10445 7e13fc7eb6160d7246ade5781734b952 93 Gene3D G3DSA:3.30.70.100 1 93 2.3E-20 T 28-03-2018 CWM22_RS08300 3319aa24dee39a211ccbb81bf4688d73 474 Gene3D G3DSA:3.40.605.10 1 264 1.2E-85 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWM22_RS08300 3319aa24dee39a211ccbb81bf4688d73 474 Pfam PF00171 Aldehyde dehydrogenase family 12 469 9.3E-152 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWM22_RS08300 3319aa24dee39a211ccbb81bf4688d73 474 SUPERFAMILY SSF53720 2 472 1.44E-146 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWM22_RS08300 3319aa24dee39a211ccbb81bf4688d73 474 Gene3D G3DSA:3.40.309.10 265 454 1.3E-61 T 28-03-2018 CWM22_RS08300 3319aa24dee39a211ccbb81bf4688d73 474 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWM22_RS08300 3319aa24dee39a211ccbb81bf4688d73 474 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWM22_RS11920 26738de2933411f4d49f9a30c5f6d21e 152 Gene3D G3DSA:1.10.10.10 3 83 0.049 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS11920 26738de2933411f4d49f9a30c5f6d21e 152 PIRSF PIRSF010607 1 151 1.3E-57 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CWM22_RS11920 26738de2933411f4d49f9a30c5f6d21e 152 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 5 147 3.4E-46 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CWM22_RS03605 1c8bddd6a48b05068c927aca190e98b2 283 Pfam PF04991 LicD family 45 257 1.8E-20 T 28-03-2018 IPR007074 LicD family CWM22_RS08485 f3b2b235a8e590f97527d248ab27b112 293 Pfam PF02517 CAAX protease self-immunity 134 224 8.7E-9 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS07585 a3f8c1d53a93dff24cd719628ab15b41 189 Pfam PF12822 ECF transporter, substrate-specific component 8 180 1.5E-19 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CWM22_RS11210 f1d61009b4adb128834fc4e5461ab778 219 Pfam PF03458 UPF0126 domain 105 176 3.1E-18 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 CWM22_RS11210 f1d61009b4adb128834fc4e5461ab778 219 Pfam PF03458 UPF0126 domain 9 82 5.8E-20 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 CWM22_RS01585 72319bcef5e065b3dfade425eb701d26 237 Pfam PF04172 LrgB-like family 21 233 2.2E-67 T 28-03-2018 IPR007300 CidB/LrgB family CWM22_RS02545 9dd9c287172440e5c3bcfc863dc7caf3 221 SUPERFAMILY SSF53271 76 219 1.02E-18 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWM22_RS02545 9dd9c287172440e5c3bcfc863dc7caf3 221 Gene3D G3DSA:3.40.50.2020 29 221 3.1E-20 T 28-03-2018 CWM22_RS00740 a22bf023486302c8d296d8dbd2e69607 113 Pfam PF05595 Domain of unknown function (DUF771) 18 110 2.3E-25 T 28-03-2018 IPR008489 Protein of unknown function DUF771 CWM22_RS09820 fe5bc4d5ca003fa7a43ea68a7d6708d4 241 Pfam PF08346 AntA/AntB antirepressor 17 85 9.0E-25 T 28-03-2018 IPR013557 AntA/AntB antirepressor CWM22_RS09820 fe5bc4d5ca003fa7a43ea68a7d6708d4 241 Pfam PF03374 Phage antirepressor protein KilAC domain 124 234 2.4E-33 T 28-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 CWM22_RS07830 41e8b7013dc9d1d6543b20a1eaaab67a 419 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 332 406 2.7E-9 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CWM22_RS13100 78cb6e1666fbc6a3ee93ac455bf30236 676 TIGRFAM TIGR01654 bact_immun_7tm: bacteriocin-associated integral membrane protein 1 675 3.8E-85 T 28-03-2018 IPR006541 Bacteriocin-associated integral membrane protein CWM22_RS13100 78cb6e1666fbc6a3ee93ac455bf30236 676 Pfam PF07242 Protein of unknown function (DUF1430) 576 675 1.8E-23 T 28-03-2018 IPR006541 Bacteriocin-associated integral membrane protein CWM22_RS03075 3e4fa70f84f0de4d98a833df25c85ba1 62 Pfam PF11676 Protein of unknown function (DUF3272) 3 62 1.6E-28 T 28-03-2018 IPR021690 Protein of unknown function DUF3272 CWM22_RS12165 a25956a8a94dc5e9c522ec5726f44beb 558 SUPERFAMILY SSF52540 23 100 3.14E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12165 a25956a8a94dc5e9c522ec5726f44beb 558 SUPERFAMILY SSF52540 129 322 3.14E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS12165 a25956a8a94dc5e9c522ec5726f44beb 558 Gene3D G3DSA:3.40.50.300 4 362 3.0E-15 T 28-03-2018 CWM22_RS09190 cb2edc3f4371a1ffca70b178e23a0677 228 Pfam PF10979 Protein of unknown function (DUF2786) 4 43 4.4E-12 T 28-03-2018 IPR024498 Domain of unknown function DUF2786 CWM22_RS12620 22d77aef7c011be21ba3b885ded7f257 279 SUPERFAMILY SSF81345 5 259 2.48E-20 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWM22_RS12620 22d77aef7c011be21ba3b885ded7f257 279 Pfam PF00950 ABC 3 transport family 3 263 1.0E-37 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CWM22_RS12620 22d77aef7c011be21ba3b885ded7f257 279 Gene3D G3DSA:1.10.3470.10 1 274 2.4E-23 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWM22_RS01195 aa2e67067ae358aabc2aa98d778b9a7a 448 Pfam PF03611 PTS system sugar-specific permease component 9 404 3.8E-148 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 CWM22_RS03955 d006771819c8e172b5ed7cdac4e4d603 158 Pfam PF05565 Siphovirus Gp157 4 158 1.4E-37 T 28-03-2018 IPR008840 Siphovirus Gp157 CWM22_RS03955 d006771819c8e172b5ed7cdac4e4d603 158 SUPERFAMILY SSF161266 39 158 2.22E-6 T 28-03-2018 CWM22_RS06130 f5e30c80d8c4d33f864b05afc80a91ca 212 Pfam PF13151 Protein of unknown function (DUF3990) 40 192 3.0E-16 T 28-03-2018 IPR025051 Protein of unknown function DUF3990 CWM22_RS06130 f5e30c80d8c4d33f864b05afc80a91ca 212 Gene3D G3DSA:3.90.175.10 5 80 7.2E-4 T 28-03-2018 CWM22_RS10830 1ec8851f48a0145b891daac4115dc331 124 Pfam PF06115 Domain of unknown function (DUF956) 1 116 1.2E-40 T 28-03-2018 IPR010360 Protein of unknown function DUF956 CWM22_RS10830 1ec8851f48a0145b891daac4115dc331 124 PIRSF PIRSF021265 1 123 9.5E-51 T 28-03-2018 IPR010360 Protein of unknown function DUF956 CWM22_RS10885 f29a155403ef55482b7781e32163c6be 221 Pfam PF02517 CAAX protease self-immunity 125 211 4.7E-16 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS12655 bb4c21b0a105c39d2cf15e6819bac6cf 95 Gene3D G3DSA:1.20.950.20 3 94 2.7E-4 T 28-03-2018 CWM22_RS10775 4214c1bd53ae919cb1a4a6e6d55792bd 274 Gene3D G3DSA:1.10.3720.10 12 273 3.1E-37 T 28-03-2018 CWM22_RS10775 4214c1bd53ae919cb1a4a6e6d55792bd 274 SUPERFAMILY SSF161098 69 255 8.11E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS10775 4214c1bd53ae919cb1a4a6e6d55792bd 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 271 1.4E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS07795 21e3c4ce74217628ab249bec8c297411 118 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 6 107 2.0E-25 T 28-03-2018 IPR019277 Protein of unknown function DUF2304 CWM22_RS07280 8211f01f6128cf1aa2a42c51d7f342d5 77 Pfam PF11184 Protein of unknown function (DUF2969) 1 76 8.4E-25 T 28-03-2018 IPR021351 Protein of unknown function DUF2969 CWM22_RS08210 9ac756b307a15bb0964bfc2c9ea51a53 271 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 266 5.4E-53 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CWM22_RS08210 9ac756b307a15bb0964bfc2c9ea51a53 271 Pfam PF09323 Domain of unknown function (DUF1980) 1 178 1.0E-60 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CWM22_RS10310 f4393a8410e5edbccb1e1bb2206fb5bf 242 PIRSF PIRSF006648 3 242 4.1E-14 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWM22_RS10310 f4393a8410e5edbccb1e1bb2206fb5bf 242 Pfam PF12698 ABC-2 family transporter protein 43 234 4.3E-13 T 28-03-2018 CWM22_RS03735 c3d415ff6ff1db04b462e7483821d4db 500 Pfam PF03606 C4-dicarboxylate anaerobic carrier 11 498 2.4E-150 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CWM22_RS04460 4e59267cfaf760444eb20cbf9e51a021 514 TIGRFAM TIGR03713 acc_sec_asp1: accessory Sec system protein Asp1 3 512 4.6E-153 T 28-03-2018 IPR022372 Accessory secretory system protein Asp1 GO:0015031 CWM22_RS04460 4e59267cfaf760444eb20cbf9e51a021 514 Pfam PF16993 Accessory Sec system protein Asp1 3 511 4.1E-154 T 28-03-2018 IPR022372 Accessory secretory system protein Asp1 GO:0015031 CWM22_RS03790 c2c28dc08377bec049d53a6c47265c94 421 PIRSF PIRSF021438 1 392 7.5E-125 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CWM22_RS03790 c2c28dc08377bec049d53a6c47265c94 421 Pfam PF04914 DltD protein 42 389 1.6E-121 T 28-03-2018 IPR006998 DltD CWM22_RS03790 c2c28dc08377bec049d53a6c47265c94 421 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 9 389 1.7E-139 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CWM22_RS11830 741dba8cae63adfc4ac95780d331d18f 200 Pfam PF00881 Nitroreductase family 10 177 1.7E-14 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWM22_RS11830 741dba8cae63adfc4ac95780d331d18f 200 SUPERFAMILY SSF55469 3 199 4.58E-67 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWM22_RS11830 741dba8cae63adfc4ac95780d331d18f 200 Gene3D G3DSA:3.40.109.10 2 198 3.0E-26 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWM22_RS02700 e86537d15bb8b684c2786ddf55616728 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 124 1.1E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWM22_RS02700 e86537d15bb8b684c2786ddf55616728 129 SUPERFAMILY SSF54593 2 126 1.16E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS02700 e86537d15bb8b684c2786ddf55616728 129 Gene3D G3DSA:3.10.180.10 1 128 2.4E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWM22_RS10855 00cf8352b923ca20d84567d61bb8fd09 157 Pfam PF01420 Type I restriction modification DNA specificity domain 36 156 2.5E-8 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CWM22_RS10855 00cf8352b923ca20d84567d61bb8fd09 157 SUPERFAMILY SSF116734 22 157 1.1E-22 T 28-03-2018 CWM22_RS10855 00cf8352b923ca20d84567d61bb8fd09 157 Gene3D G3DSA:3.90.220.20 13 157 9.5E-19 T 28-03-2018 CWM22_RS09550 412f3786b3e864d44da6e2c890466fc5 249 Pfam PF03374 Phage antirepressor protein KilAC domain 152 247 2.6E-21 T 28-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 CWM22_RS09550 412f3786b3e864d44da6e2c890466fc5 249 SMART SM01040 13 99 1.2E-42 T 28-03-2018 IPR003497 BRO N-terminal domain CWM22_RS09550 412f3786b3e864d44da6e2c890466fc5 249 Pfam PF02498 BRO family, N-terminal domain 14 99 2.3E-30 T 28-03-2018 IPR003497 BRO N-terminal domain CWM22_RS08060 a576518da91e107d9977e7f25c2cf99a 88 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 16 83 1.0E-21 T 28-03-2018 IPR018656 Domain of unknown function DUF2087 CWM22_RS06335 a73c5598dc666c04fe3cc85925ccf275 117 Pfam PF12666 PrgI family protein 4 95 4.7E-17 T 28-03-2018 IPR024414 Uncharacterised protein family PrgI CWM22_RS01535 af79d6e7e0c9e24b9d2e354d13736368 259 Pfam PF06182 ABC-2 family transporter protein 33 254 3.8E-19 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CWM22_RS07425 3cedb821686817d1b47e46c8a58b4691 112 Pfam PF03477 ATP cone domain 1 92 9.0E-18 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CWM22_RS10675 6bcb7a57d09cac27377c94f90f056142 179 Pfam PF07456 Heptaprenyl diphosphate synthase component I 14 160 1.1E-44 T 28-03-2018 IPR010898 Heptaprenyl diphosphate synthase component I CWM22_RS10675 6bcb7a57d09cac27377c94f90f056142 179 PIRSF PIRSF027391 1 176 2.7E-52 T 28-03-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I CWM22_RS07985 8d109bb22f9b3b7e49963e5a99cd13e1 56 Pfam PF11240 Protein of unknown function (DUF3042) 3 55 1.8E-26 T 28-03-2018 IPR021402 Protein of unknown function DUF3042 CWM22_RS06555 8ed62f7a93904409f2ffa76229ce86e8 121 Pfam PF05713 Bacterial mobilisation protein (MobC) 62 103 1.4E-14 T 28-03-2018 IPR008687 Bacterial mobilisation CWM22_RS07770 6b62e1064885e0adee0b633e69e1f2e2 158 Gene3D G3DSA:3.10.350.10 105 158 1.3E-5 T 28-03-2018 CWM22_RS09165 7130e81672bb83b15bf1e81602dd29df 150 SUPERFAMILY SSF52833 49 124 2.42E-8 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS09165 7130e81672bb83b15bf1e81602dd29df 150 Gene3D G3DSA:3.40.30.10 56 146 1.1E-8 T 28-03-2018 CWM22_RS07880 a9fff5dee47d35531c26ac28587761bd 347 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 314 345 2.6E-4 T 28-03-2018 CWM22_RS03475 d1977d4505a19846a3227337958226a7 340 Pfam PF02562 PhoH-like protein 111 314 1.4E-94 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CWM22_RS03475 d1977d4505a19846a3227337958226a7 340 SUPERFAMILY SSF52540 98 312 1.4E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWM22_RS03475 d1977d4505a19846a3227337958226a7 340 Gene3D G3DSA:3.40.50.300 109 314 3.9E-29 T 28-03-2018 CWM22_RS08850 0f1f5df603f1c4cceddbbda0651c7955 126 Pfam PF02566 OsmC-like protein 31 117 7.7E-7 T 28-03-2018 IPR003718 OsmC/Ohr family CWM22_RS08850 0f1f5df603f1c4cceddbbda0651c7955 126 SUPERFAMILY SSF82784 20 119 8.64E-11 T 28-03-2018 IPR003718 OsmC/Ohr family CWM22_RS08850 0f1f5df603f1c4cceddbbda0651c7955 126 Gene3D G3DSA:3.30.300.20 1 125 3.8E-6 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWM22_RS12555 cf7ccaf6a19258f2e042b5377c75e70c 458 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 9 456 1.4E-114 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWM22_RS12555 cf7ccaf6a19258f2e042b5377c75e70c 458 Pfam PF02378 Phosphotransferase system, EIIC 25 385 2.1E-53 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWM22_RS12555 cf7ccaf6a19258f2e042b5377c75e70c 458 PIRSF PIRSF006351 1 458 2.7E-124 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWM22_RS10745 612da942a6a63d35dc8d0839747d59ce 455 Gene3D G3DSA:3.30.70.360 203 368 4.2E-42 T 28-03-2018 CWM22_RS10745 612da942a6a63d35dc8d0839747d59ce 455 Pfam PF01546 Peptidase family M20/M25/M40 82 452 2.9E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWM22_RS10745 612da942a6a63d35dc8d0839747d59ce 455 Gene3D G3DSA:3.40.630.10 11 202 3.6E-29 T 28-03-2018 CWM22_RS10745 612da942a6a63d35dc8d0839747d59ce 455 SUPERFAMILY SSF53187 369 454 1.09E-44 T 28-03-2018 CWM22_RS10745 612da942a6a63d35dc8d0839747d59ce 455 SUPERFAMILY SSF53187 12 199 1.09E-44 T 28-03-2018 CWM22_RS10745 612da942a6a63d35dc8d0839747d59ce 455 Pfam PF07687 Peptidase dimerisation domain 197 354 2.8E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWM22_RS13295 60a106dc6cc8b92e60116b2d22b1feec 290 Pfam PF03313 Serine dehydratase alpha chain 18 274 2.1E-72 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CWM22_RS13295 60a106dc6cc8b92e60116b2d22b1feec 290 Gene3D G3DSA:1.10.4100.10 7 271 2.5E-30 T 28-03-2018 CWM22_RS13295 60a106dc6cc8b92e60116b2d22b1feec 290 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 288 5.9E-111 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWM22_RS01125 1f1be60edbf6a1612bfe5d15e06b8cf5 71 Gene3D G3DSA:1.10.10.60 18 62 0.0011 T 28-03-2018 CWM22_RS11925 d9533d347a59f61ecea1379a592355ab 112 SUPERFAMILY SSF52833 3 111 1.04E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold CWM22_RS11925 d9533d347a59f61ecea1379a592355ab 112 Pfam PF00085 Thioredoxin 35 111 4.9E-6 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWM22_RS11925 d9533d347a59f61ecea1379a592355ab 112 Gene3D G3DSA:3.40.30.10 2 112 8.4E-13 T 28-03-2018 CWM22_RS01570 76ac8c7922945fd8da9dc7d4557426c5 251 SUPERFAMILY SSF103473 69 237 4.32E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWM22_RS01570 76ac8c7922945fd8da9dc7d4557426c5 251 Pfam PF08006 Protein of unknown function (DUF1700) 1 123 9.9E-13 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 CWM22_RS12785 3d4a94f6d3ac06aa0674988af549c5c1 109 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 24 86 2.8E-7 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CWM22_RS12785 3d4a94f6d3ac06aa0674988af549c5c1 109 SUPERFAMILY SSF101386 22 98 1.18E-14 T 28-03-2018 CWM22_RS12785 3d4a94f6d3ac06aa0674988af549c5c1 109 Gene3D G3DSA:1.10.287.1080 8 94 6.5E-14 T 28-03-2018 CWM22_RS09445 b4b0393ba808454cbd743a241b374904 145 Gene3D G3DSA:3.40.630.30 1 145 2.8E-20 T 28-03-2018 CWM22_RS09445 b4b0393ba808454cbd743a241b374904 145 Pfam PF00583 Acetyltransferase (GNAT) family 20 129 2.3E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWM22_RS09445 b4b0393ba808454cbd743a241b374904 145 SUPERFAMILY SSF55729 1 139 1.46E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWM22_RS07910 b6d5ba0553ec23f6b9e89933fa79a1e6 274 Pfam PF02535 ZIP Zinc transporter 116 269 3.0E-16 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWM22_RS03560 b56fcb590433f105e351f78e5620707a 199 Pfam PF02397 Bacterial sugar transferase 6 183 1.1E-62 T 28-03-2018 IPR003362 Bacterial sugar transferase CWM22_RS10825 3685293ec55826901bc2dad78112b4b2 303 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 6 303 2.2E-112 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CWM22_RS10825 3685293ec55826901bc2dad78112b4b2 303 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 7 217 3.4E-88 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 CWM22_RS02450 9bfc00d55c50c40c4e21ea47437af735 484 Hamap MF_01941 Mid-cell-anchored protein Z [mapZ]. 1 484 23.901 T 28-03-2018 IPR030858 Mid-cell-anchored protein Z GO:0016021|GO:0051301 CWM22_RS08375 9369c403a73d1877f4daed830dfe073c 252 Pfam PF11368 Protein of unknown function (DUF3169) 13 246 9.5E-30 T 28-03-2018 IPR021509 Protein of unknown function DUF3169 CWM22_RS04970 4e47e21f5c50e5e0a8152a91ece4a1e0 156 Gene3D G3DSA:3.30.530.20 4 155 1.0E-14 T 28-03-2018 IPR023393 START-like domain CWM22_RS04970 4e47e21f5c50e5e0a8152a91ece4a1e0 156 SUPERFAMILY SSF55961 10 152 7.44E-19 T 28-03-2018 CWM22_RS04940 e05bd5078d8c88f2ad791d8151abeae7 370 Pfam PF13349 Putative adhesin 122 362 5.5E-15 T 28-03-2018 IPR025164 Putative adhesin CWM22_RS03355 02e5288f214469df6a2897c0a2696810 295 SUPERFAMILY SSF161098 11 295 3.27E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS03355 02e5288f214469df6a2897c0a2696810 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 288 2.5E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWM22_RS03355 02e5288f214469df6a2897c0a2696810 295 Gene3D G3DSA:1.10.3720.10 12 290 5.4E-41 T 28-03-2018 CWM22_RS12340 2e42ef26a1912f10d6d2028ebe2ce137 147 Pfam PF00692 dUTPase 18 128 1.4E-15 T 28-03-2018 IPR029054 dUTPase-like CWM22_RS12340 2e42ef26a1912f10d6d2028ebe2ce137 147 SUPERFAMILY SSF51283 10 147 1.03E-35 T 28-03-2018 IPR029054 dUTPase-like CWM22_RS12340 2e42ef26a1912f10d6d2028ebe2ce137 147 Gene3D G3DSA:2.70.40.10 1 131 2.0E-35 T 28-03-2018 CWM22_RS10535 8a247061571701cc8b8d2c7a40673df7 376 Pfam PF01594 AI-2E family transporter 27 360 4.6E-43 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CWM22_RS00880 1deab86323f2d36e76d7c1f0d5361032 121 Pfam PF06279 Protein of unknown function (DUF1033) 1 112 1.5E-46 T 28-03-2018 IPR010434 Protein of unknown function DUF1033 CWM22_RS12810 7a8dcb51b7a67f4da5f9a4d5a5baf26e 119 Pfam PF05595 Domain of unknown function (DUF771) 24 115 4.1E-27 T 28-03-2018 IPR008489 Protein of unknown function DUF771 CWM22_RS02930 ac2793f846b649fc2ca63961955ad720 183 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 73 164 1.1E-28 T 28-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 CWM22_RS01420 c2cdd3a9b440a938a1acec2f2dfddc5c 103 SUPERFAMILY SSF102829 10 85 7.98E-5 T 28-03-2018 IPR007838 Cell division protein ZapA-like CWM22_RS03130 cf67c39ee117f69ed897d58276cd61b2 145 Pfam PF04138 GtrA-like protein 16 141 1.8E-21 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CWM22_RS12875 d2795718fb2483919a4847aa7c1b146f 160 Pfam PF07275 Antirestriction protein (ArdA) 18 157 2.0E-15 T 28-03-2018 IPR009899 Antirestriction CWM22_RS01530 17dd7bdcb0f88dffd431fa1820148185 260 Pfam PF06182 ABC-2 family transporter protein 34 259 2.4E-43 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CWM22_RS09020 6d39f933aa7d21cb87bc842b1d2f64ed 160 Gene3D G3DSA:3.40.190.10 1 126 0.001 T 28-03-2018 CWM22_RS06080 1486589fdf9ad68791a10c7c1482a928 164 Pfam PF12687 Protein of unknown function (DUF3801) 26 152 1.4E-14 T 28-03-2018 IPR024234 Protein of unknown function DUF3801 CWM22_RS03895 c20516e250b99209160db996e565a6c4 102 Gene3D G3DSA:3.90.20.10 2 90 3.6E-5 T 28-03-2018 CWM22_RS10650 f2879f40d03fc852af09feff086775e4 309 Pfam PF01040 UbiA prenyltransferase family 17 263 5.0E-23 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CWM22_RS10650 f2879f40d03fc852af09feff086775e4 309 PIRSF PIRSF005355 2 309 1.7E-37 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CWM22_RS02645 6be70b82450a65d671aa0818149ec8b5 105 Gene3D G3DSA:3.10.450.150 3 101 3.6E-25 T 28-03-2018 CWM22_RS02645 6be70b82450a65d671aa0818149ec8b5 105 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 9 101 3.3E-28 T 28-03-2018 IPR009303 Protein of unknown function DUF960 CWM22_RS06095 9edabe4f556985ec39a94f13304d4a9b 71 Pfam PF12750 Maff2 family 1 69 2.0E-39 T 28-03-2018 IPR024272 MAFF2-related CWM22_RS12965 db1009a3049daa39eef816f832c9fc45 280 Pfam PF06114 IrrE N-terminal-like domain 39 155 9.3E-13 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CWM22_RS08150 3f83a5d2b175cf46bb350c28b7ff8b68 74 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 5 72 6.1E-17 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CWM22_RS08150 3f83a5d2b175cf46bb350c28b7ff8b68 74 Pfam PF06612 Protein of unknown function (DUF1146) 13 62 7.0E-13 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CWM22_RS04090 8429e48f964eacea1f84cad85f21d6bd 173 Pfam PF14265 Domain of unknown function (DUF4355) 31 150 8.5E-30 T 28-03-2018 IPR025580 Protein of unknown function DUF4355 CWM22_RS00910 2a59b755bb01591511d79bfd482221ee 97 Pfam PF11773 Type II secretory pathway pseudopilin 13 94 1.6E-33 T 28-03-2018 IPR021749 Type II secretory pathway pseudopilin CWM22_RS00950 9d6a032d8ae1aad7336109c06efbc7de 50 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 12 50 7.5E-9 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) CWM22_RS07290 216909730506ccc23cdc84dbf72eacc4 205 Pfam PF14014 Protein of unknown function (DUF4230) 51 191 3.0E-12 T 28-03-2018 IPR025324 Protein of unknown function DUF4230 CWM22_RS00895 829d5c8329601977085ac8ad12ecbae1 342 PRINTS PR00812 Bacterial general secretion pathway protein F signature 308 322 8.7E-8 T 28-03-2018 IPR003004 GspF/PilC family CWM22_RS00895 829d5c8329601977085ac8ad12ecbae1 342 PRINTS PR00812 Bacterial general secretion pathway protein F signature 119 147 8.7E-8 T 28-03-2018 IPR003004 GspF/PilC family CWM22_RS00895 829d5c8329601977085ac8ad12ecbae1 342 PRINTS PR00812 Bacterial general secretion pathway protein F signature 324 342 8.7E-8 T 28-03-2018 IPR003004 GspF/PilC family CWM22_RS00895 829d5c8329601977085ac8ad12ecbae1 342 Pfam PF00482 Type II secretion system (T2SS), protein F 30 147 1.0E-7 T 28-03-2018 IPR018076 Type II secretion system F domain CWM22_RS00895 829d5c8329601977085ac8ad12ecbae1 342 Pfam PF00482 Type II secretion system (T2SS), protein F 215 335 9.7E-16 T 28-03-2018 IPR018076 Type II secretion system F domain CWM22_RS06680 5fc73132e35190755903ec84262491ce 656 Pfam PF02687 FtsX-like permease family 82 176 5.5E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWM22_RS06680 5fc73132e35190755903ec84262491ce 656 PIRSF PIRSF018968 1 655 5.5E-57 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWM22_RS06350 88e366ee31c38055ab2553b089b589a4 336 Pfam PF07751 Abi-like protein 41 237 2.7E-28 T 28-03-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like CWM22_RS04610 107edadb5bdae9100dd8922054e1a475 261 Pfam PF04536 TPM domain 38 160 2.1E-27 T 28-03-2018 IPR007621 TPM domain CWM22_RS00080 70894148c1ef4d88047dd25d907f32e7 156 Gene3D G3DSA:1.10.1740.10 1 75 1.1E-10 T 28-03-2018 CWM22_RS04315 6592a70a01d474916eaef22eb725a3c5 388 Pfam PF01594 AI-2E family transporter 34 365 4.4E-73 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CWM22_RS08360 dcdb23a32106d78987e29b09fe843345 229 Pfam PF02517 CAAX protease self-immunity 128 215 4.9E-18 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWM22_RS01425 4000c7d04123d821978acd02d87261ac 182 Pfam PF02674 Colicin V production protein 2 166 1.3E-23 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CWM22_RS01340 ef0d3c61ee4f165842067b20fe73a023 127 Pfam PF12784 PD-(D/E)XK nuclease family transposase 10 106 2.3E-7 T 28-03-2018 CWM22_RS04925 882e2ed93611322566415648b78444c7 119 Pfam PF06993 Protein of unknown function (DUF1304) 11 115 9.2E-34 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 CWM22_RS08475 e54e3f369b70b8263dd9ec648585e75f 32 Pfam PF16935 Putative Holin-like Toxin (Hol-Tox) 2 31 1.2E-7 T 28-03-2018 IPR031616 Putative Holin-like Toxin (Hol-Tox) CWM22_RS06160 579828177795da4cd3a17039ca173e23 212 SUPERFAMILY SSF50249 76 171 8.78E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWM22_RS06160 579828177795da4cd3a17039ca173e23 212 Gene3D G3DSA:2.40.50.140 62 176 1.9E-16 T 28-03-2018 CWM22_RS06160 579828177795da4cd3a17039ca173e23 212 Pfam PF00436 Single-strand binding protein family 77 156 4.3E-10 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWM22_RS08945 e32c92409c1f016c7d616150d7afd739 271 Pfam PF01757 Acyltransferase family 3 243 1.1E-10 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CWM22_RS11315 8b97410ff4f0c3e024d8094579e71b16 109 Gene3D G3DSA:1.20.1250.10 12 108 0.0011 T 28-03-2018 CWM22_RS09985 540a72a45fc87af3f8fa1a1709649d88 295 Pfam PF01925 Sulfite exporter TauE/SafE 3 151 1.9E-10 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CWM22_RS01790 92fe60b9f43e61b9f5546f88bfd51e51 219 Pfam PF02361 Cobalt transport protein 10 184 2.4E-9 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CWM22_RS08835 886e8466bc63af6fa2f2f0bac1e7a7be 232 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 21 210 1.7E-29 T 28-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CWM22_RS08835 886e8466bc63af6fa2f2f0bac1e7a7be 232 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 22 219 4.8E-25 T 28-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CWM22_RS06745 d9bcbcce0fcbc02377d8d16af9731635 484 Gene3D G3DSA:3.40.50.1010 20 120 0.001 T 28-03-2018 IPR029060 PIN domain-like CWM22_RS05190 fef469988496295f01314949170b94e5 215 Pfam PF02397 Bacterial sugar transferase 13 187 2.1E-64 T 28-03-2018 IPR003362 Bacterial sugar transferase CWM22_RS11820 ad1accc5c2657541db4ccdc5c592b17b 77 Pfam PF04226 Transglycosylase associated protein 31 75 1.1E-11 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CWM22_RS11250 589ef5cac1db8ded015d0a34cafb8b95 229 Gene3D G3DSA:2.130.10.130 11 203 4.6E-4 T 28-03-2018 CWM22_RS03770 ee3256866407f01abc64d3642c401a57 41 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 2 41 1.3E-20 T 28-03-2018 IPR021008 Protein of unknown function DUF3687 CWM22_RS13300 f071d9b4a2d1aaf4adb0b335344d1f40 201 Gene3D G3DSA:2.40.128.50 114 200 2.3E-23 T 28-03-2018 IPR027279 D-aminopeptidase/lipoprotein domain CWM22_RS13300 f071d9b4a2d1aaf4adb0b335344d1f40 201 Pfam PF12182 Bacterial lipoprotein 116 199 1.7E-12 T 28-03-2018 IPR020961 Domain of unknown function DUF3642, lipoprotein CWM22_RS08370 4c9358b0ceb6b01122864028b6497e50 169 Pfam PF11683 Protein of unknown function (DUF3278) 1 117 1.2E-10 T 28-03-2018 IPR021697 Protein of unknown function DUF3278 CWM22_RS13150 75faa58421618b41ae9a4f2e34f58a9a 260 PIRSF PIRSF009136 1 260 6.0E-117 T 28-03-2018 IPR016546 Maltodextrose utilization protein MalA CWM22_RS11570 82d7e8e891a47be966159747ffaff35b 129 Pfam PF08570 Protein of unknown function (DUF1761) 7 124 1.1E-19 T 28-03-2018 IPR013879 Protein of unknown function DUF1761 CWM22_RS08045 32597cb13983bceb41156bc660dbdb12 225 Pfam PF16316 Domain of unknown function (DUF4956) 29 145 2.2E-13 T 28-03-2018 IPR032531 Protein of unknown function DUF4956 CWM22_RS09240 ec94928c84776e9f141b54202e8ae66a 280 Pfam PF06161 Protein of unknown function (DUF975) 1 270 3.5E-43 T 28-03-2018 IPR010380 Protein of unknown function DUF975 CWM22_RS08960 2fc1c2c055286d7765a7c040d64efc6c 442 Pfam PF06782 Uncharacterised protein family (UPF0236) 31 423 2.5E-20 T 28-03-2018 IPR009620 Uncharacterised protein family UPF0236 CWM22_RS00195 39033ee8209a36429c906eb351325aad 171 Pfam PF04093 rod shape-determining protein MreD 5 165 8.9E-15 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CWM22_RS13390 75910b71a2f6cfc9c79b5835703e32f8 859 Pfam PF09586 Bacterial membrane protein YfhO 15 836 2.3E-247 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO CWM22_RS08940 45fed9023569ce4df6e622d0e5246460 95 Pfam PF01757 Acyltransferase family 5 71 5.3E-9 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CWM22_RS03160 fd50e496eb3782a42a2d61a5e47061cd 87 Pfam PF04024 PspC domain 5 62 3.6E-12 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CWM22_RS11230 790b9542a3222449fc44b1c91161a52d 22 TIGRFAM TIGR04079 phero_cyc_pep: KxxxW-cyclized secreted peptide 1 20 1.5E-12 T 28-03-2018 IPR023903 Cyclised secreted peptide CWM22_RS00275 e4f31f64d24f322232bbe66a34dff6ec 261 Pfam PF06182 ABC-2 family transporter protein 36 258 2.8E-32 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CWM22_RS12840 0f5d0565236c4c8c906f1ddbd0a5c69d 134 Pfam PF12648 TcpE family 14 113 6.9E-19 T 28-03-2018 IPR025608 TcpE family CWM22_RS01955 58a622ccd3573642dcbe3b14a70f43d0 161 Pfam PF07155 ECF-type riboflavin transporter, S component 5 149 5.7E-30 T 28-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CWM22_RS03905 57c97a1ad1c793e9b3b3587c9b47b587 126 Pfam PF06114 IrrE N-terminal-like domain 8 91 5.8E-8 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CWM22_RS01115 f13aaaa1afef882e887acbfc2e6f0455 306 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 20 297 2.2E-18 T 28-03-2018 IPR010106 Recombination-promoting nuclease RpnA CWM22_RS01115 f13aaaa1afef882e887acbfc2e6f0455 306 Pfam PF12784 PD-(D/E)XK nuclease family transposase 21 240 5.0E-16 T 28-03-2018 CWM22_RS03990 6f0aa1751e823eef330a7c18ae9bd45e 77 Pfam PF11753 Protein of unknwon function (DUF3310) 7 66 1.3E-18 T 28-03-2018 IPR021739 SaV-like CWM22_RS07825 7a865b3595b9f4face30086dd5027a49 435 Pfam PF09913 Predicted membrane protein (DUF2142) 12 390 6.9E-89 T 28-03-2018 IPR018674 Protein of unknown function DUF2142, membrane CWM22_RS09660 ba2c90d2658808d01b141f40c9c5d1b5 88 Gene3D G3DSA:1.10.287.560 25 78 4.9E-4 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CWM22_RS08775 582afefcbed0bfa35913b4ab7a78af3e 199 Pfam PF07853 Protein of unknown function (DUF1648) 15 58 3.0E-11 T 28-03-2018 IPR012867 Domain of unknown function DUF1648 CWM22_RS06105 c26eaef3b41d71265b8bb40fc2740cd1 122 Pfam PF12666 PrgI family protein 5 91 2.1E-23 T 28-03-2018 IPR024414 Uncharacterised protein family PrgI CWM22_RS05790 b7d63682b62059180493e730847b60fb 129 Gene3D G3DSA:1.10.10.10 4 128 4.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWM22_RS12660 4d17984de0e47eabbebc33fd54a15c32 224 Pfam PF02517 CAAX protease self-immunity 117 208 6.1E-15 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880