locus-tag	class	description
JM964_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JM964_RS00010	COG0592	DNA-directed DNA polymerase activity
JM964_RS00030	COG0012	GTP binding
JM964_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
JM964_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JM964_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JM964_RS00060	COG0037	tRNA processing
JM964_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JM964_RS00180	COG1792	Involved in formation and maintenance of cell shape
JM964_RS00195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JM964_RS00200	COG0436	Aminotransferase
JM964_RS00205	COG1381	Involved in DNA repair and RecF pathway recombination
JM964_RS00210	COG0416	fatty acid biosynthetic process
JM964_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JM964_RS00225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JM964_RS00240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JM964_RS00245	COG0138	bifunctional purine biosynthesis protein purh
JM964_RS00255	COG0151	Belongs to the GarS family
JM964_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JM964_RS00275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JM964_RS00295	COG1132	(ABC) transporter
JM964_RS00305	COG2255	four-way junction helicase activity
JM964_RS00315	COG0546	phosphoglycolate phosphatase activity
JM964_RS00330	COG0285	dihydrofolate synthase activity
JM964_RS00340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JM964_RS00345	COG0632	four-way junction helicase activity
JM964_RS00350	COG0519	Catalyzes the synthesis of GMP from XMP
JM964_RS00365	COG1393	Belongs to the ArsC family
JM964_RS00370	COG4472	Bacterial protein of unknown function (DUF965)
JM964_RS00375	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JM964_RS00380	COG3906	Belongs to the UPF0473 family
JM964_RS00390	COG0051	transcription antitermination factor activity, RNA binding
JM964_RS00395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JM964_RS00400	COG0088	Forms part of the polypeptide exit tunnel
JM964_RS00405	COG0089	rRNA binding
JM964_RS00410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JM964_RS00415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JM964_RS00420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JM964_RS00425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JM964_RS00430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JM964_RS00435	COG0255	Belongs to the universal ribosomal protein uL29 family
JM964_RS00440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JM964_RS00445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JM964_RS00450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JM964_RS00455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JM964_RS00460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JM964_RS00465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JM964_RS00470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JM964_RS00475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JM964_RS00480	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JM964_RS00485	COG1841	ribosomal large subunit assembly
JM964_RS00495	COG0201	protein transport
JM964_RS00500	COG0563	adenylate kinase activity
JM964_RS00505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JM964_RS00510	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JM964_RS00515	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JM964_RS00525	COG0202	RNA polymerase activity
JM964_RS00635	COG1121	(ABC) transporter
JM964_RS00640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JM964_RS00645	COG3443	Belongs to the bacterial solute-binding protein 9 family
JM964_RS00645	COG0803	Belongs to the bacterial solute-binding protein 9 family
JM964_RS00685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JM964_RS00690	COG0085	RNA polymerase activity
JM964_RS00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JM964_RS00705	COG1619	proteins homologs of microcin C7 resistance protein MccF
JM964_RS00710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JM964_RS00715	COG1459	type II secretion system
JM964_RS00720	COG4537	Required for transformation and DNA binding
JM964_RS00750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JM964_RS00760	COG0285	dihydrofolate synthase activity
JM964_RS00765	COG1363	Peptidase, m42
JM964_RS00775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JM964_RS00785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JM964_RS00815	COG0459	protein refolding
JM964_RS00825	COG0049	tRNA binding
JM964_RS00830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JM964_RS00840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JM964_RS00860	COG0126	phosphoglycerate kinase activity
JM964_RS00870	COG0789	Transcriptional regulator
JM964_RS00875	COG0174	glutamine synthetase
JM964_RS00890	COG1214	PFAM Peptidase M22, glycoprotease
JM964_RS00900	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JM964_RS00910	COG2207	Transcriptional regulator
JM964_RS00920	COG1175	transmembrane transport
JM964_RS00925	COG0395	ABC-type sugar transport system, permease component
JM964_RS00945	COG2855	membrane
JM964_RS00955	COG1846	Transcriptional regulator
JM964_RS00955	COG0456	acetyltransferase
JM964_RS00970	COG1131	(ABC) transporter
JM964_RS00975	COG2081	HI0933 family
JM964_RS00980	COG2723	6-phospho-beta-galactosidase activity
JM964_RS00990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM964_RS01005	COG3959	Transketolase, thiamine diphosphate binding domain
JM964_RS01010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JM964_RS01015	COG0584	glycerophosphoryl diester phosphodiesterase
JM964_RS01020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JM964_RS01025	COG2222	sugar isomerase
JM964_RS01050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JM964_RS01055	COG1882	Formate acetyltransferase
JM964_RS01070	COG2910	NAD(P)H-binding
JM964_RS01085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JM964_RS01090	COG0681	Belongs to the peptidase S26 family
JM964_RS01115	COG0366	Alpha amylase catalytic
JM964_RS01120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JM964_RS01120	COG1263	PTS System
JM964_RS01125	COG2188	Transcriptional regulator
JM964_RS01140	COG1193	negative regulation of DNA recombination
JM964_RS01155	COG0656	L-ascorbic acid biosynthetic process
JM964_RS01160	COG3118	belongs to the thioredoxin family
JM964_RS01165	COG0318	PFAM AMP-dependent synthetase and ligase
JM964_RS01170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JM964_RS01170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JM964_RS01195	COG1115	amino acid carrier protein
JM964_RS01200	COG0668	transmembrane transport
JM964_RS01210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JM964_RS01220	COG0167	dihydroorotate dehydrogenase activity
JM964_RS01225	COG2843	Capsule synthesis protein
JM964_RS01250	COG0561	phosphatase activity
JM964_RS01265	COG1131	(ABC) transporter
JM964_RS01270	COG1309	transcriptional regulator
JM964_RS01275	COG1511	domain protein
JM964_RS01300	COG1346	cytolysis
JM964_RS01305	COG2116	formate transmembrane transporter activity
JM964_RS01310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JM964_RS01315	COG0433	COG0433 Predicted ATPase
JM964_RS01320	COG0494	nUDIX hydrolase
JM964_RS01325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JM964_RS01345	COG1349	DNA-binding transcription factor activity
JM964_RS01350	COG0698	ribose 5-phosphate isomerase
JM964_RS01355	COG0698	ribose 5-phosphate isomerase
JM964_RS01360	COG1105	Belongs to the carbohydrate kinase PfkB family
JM964_RS01370	COG3711	transcriptional antiterminator
JM964_RS01380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JM964_RS01380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JM964_RS01395	COG1408	metallophosphoesterase
JM964_RS01400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JM964_RS01405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JM964_RS01410	COG0124	histidyl-tRNA synthetase
JM964_RS01415	COG1064	alcohol dehydrogenase
JM964_RS01420	COG1012	belongs to the aldehyde dehydrogenase family
JM964_RS01420	COG1454	alcohol dehydrogenase
JM964_RS01430	COG4988	ABC transporter
JM964_RS01435	COG1132	(ABC) transporter
JM964_RS01450	COG1129	ABC transporter
JM964_RS01455	COG0534	Mate efflux family protein
JM964_RS01460	COG1132	(ABC) transporter
JM964_RS01470	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JM964_RS01485	COG1304	FMN binding
JM964_RS01490	COG1132	(ABC) transporter
JM964_RS01495	COG1132	(ABC) transporter
JM964_RS01500	COG3830	Belongs to the UPF0237 family
JM964_RS01505	COG2848	UPF0210 protein
JM964_RS01510	COG0588	phosphoglycerate mutase activity
JM964_RS01525	COG1396	sequence-specific DNA binding
JM964_RS01550	COG1420	regulation of RNA biosynthetic process
JM964_RS01555	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JM964_RS01560	COG0443	Heat shock 70 kDa protein
JM964_RS01565	COG0484	heat shock protein binding
JM964_RS01570	COG0095	Lipoate-protein ligase
JM964_RS01580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JM964_RS01585	COG0765	amino acid transport
JM964_RS01590	COG3655	Transcriptional regulator
JM964_RS01600	COG2217	Heavy metal translocating P-type atpase
JM964_RS01625	COG4475	Protein of unknown function (DUF436)
JM964_RS01635	COG1064	alcohol dehydrogenase
JM964_RS01650	COG0544	peptidyl-prolyl cis-trans isomerase activity
JM964_RS01655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JM964_RS01665	COG0251	oxidation-reduction process
JM964_RS01670	COG0626	cystathionine gamma-synthase activity
JM964_RS01675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JM964_RS01680	COG2964	Protein conserved in bacteria
JM964_RS01720	COG3343	RNA polymerase activity
JM964_RS01725	COG0504	CTP synthase activity
JM964_RS01735	COG0191	fructose-bisphosphate aldolase activity
JM964_RS01740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JM964_RS01775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JM964_RS01800	COG0589	response to stress
JM964_RS01805	COG0436	Aminotransferase
JM964_RS01810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JM964_RS01815	COG1335	isochorismatase
JM964_RS01820	COG0335	large ribosomal subunit rRNA binding
JM964_RS01830	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JM964_RS01835	COG0154	amidase activity
JM964_RS01840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JM964_RS01845	COG1609	Transcriptional regulator
JM964_RS01850	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JM964_RS01855	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JM964_RS01865	COG3142	Participates in the control of copper homeostasis
JM964_RS01880	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JM964_RS01885	COG1534	Rna-binding protein
JM964_RS01890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JM964_RS01895	COG1713	HD superfamily hydrolase involved in NAD metabolism
JM964_RS01905	COG1335	isochorismatase
JM964_RS01910	COG0799	negative regulation of ribosome biogenesis
JM964_RS01915	COG2226	methyltransferase
JM964_RS01925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JM964_RS01930	COG0789	Transcriptional regulator
JM964_RS01940	COG0242	peptide deformylase activity
JM964_RS01950	COG1640	4-alpha-glucanotransferase
JM964_RS01955	COG0058	SHG alpha-glucan phosphorylase activity
JM964_RS01970	COG1263	PTS System
JM964_RS01970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JM964_RS01970	COG2190	(PTS) system
JM964_RS01975	COG0217	transcriptional regulatory protein
JM964_RS01985	COG4720	Psort location CytoplasmicMembrane, score
JM964_RS01995	COG1054	Belongs to the UPF0176 family
JM964_RS02005	COG1122	ATPase activity
JM964_RS02020	COG0357	Ribosomal RNA small subunit methyltransferase G
JM964_RS02025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JM964_RS02030	COG3331	DNA recombination
JM964_RS02035	COG4474	Belongs to the UPF0398 family
JM964_RS02040	COG3599	regulation of cell shape
JM964_RS02050	COG0116	Belongs to the methyltransferase superfamily
JM964_RS02060	COG1854	S-ribosylhomocysteine lyase activity
JM964_RS02065	COG1418	mRNA catabolic process
JM964_RS02070	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS02075	COG1253	flavin adenine dinucleotide binding
JM964_RS02080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JM964_RS02090	COG2514	catechol 2,3-dioxygenase activity
JM964_RS02095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JM964_RS02100	COG1733	regulation of RNA biosynthetic process
JM964_RS02115	COG1227	inorganic diphosphatase activity
JM964_RS02125	COG0789	Transcriptional regulator
JM964_RS02140	COG0826	peptidase U32
JM964_RS02150	COG4443	Transcriptional Coactivator p15 (PC4)
JM964_RS02160	COG1609	Transcriptional regulator
JM964_RS02175	COG1175	transmembrane transport
JM964_RS02180	COG3833	ABC-type maltose transport systems, permease component
JM964_RS02190	COG1268	BioY protein
JM964_RS02195	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JM964_RS02200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JM964_RS02205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JM964_RS02210	COG1136	(ABC) transporter
JM964_RS02215	COG0577	efflux transmembrane transporter activity
JM964_RS02225	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JM964_RS02235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JM964_RS02245	COG3859	Proton-coupled thiamine transporter YuaJ
JM964_RS02265	COG0772	Belongs to the SEDS family
JM964_RS02270	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JM964_RS02285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JM964_RS02290	COG0149	triose-phosphate isomerase activity
JM964_RS02300	COG1078	dGTPase activity
JM964_RS02335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JM964_RS02345	COG2884	Cell division ATP-binding protein ftsE
JM964_RS02350	COG2177	Part of the ABC transporter FtsEX involved in
JM964_RS02375	COG1132	(ABC) transporter
JM964_RS02380	COG1132	(ABC) transporter
JM964_RS02385	COG1011	Hydrolase
JM964_RS02405	COG1737	Transcriptional regulator
JM964_RS02415	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JM964_RS02420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JM964_RS02425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JM964_RS02435	COG2814	Major facilitator Superfamily
JM964_RS02440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JM964_RS02450	COG0557	exoribonuclease II activity
JM964_RS02455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JM964_RS02465	COG1122	ATPase activity
JM964_RS02485	COG1063	alcohol dehydrogenase
JM964_RS02500	COG2217	Heavy metal translocating P-type atpase
JM964_RS02505	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JM964_RS02515	COG1136	(ABC) transporter
JM964_RS02530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JM964_RS02530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JM964_RS02540	COG1832	CoA-binding protein
JM964_RS02550	COG0343	queuine tRNA-ribosyltransferase activity
JM964_RS02560	COG1609	Transcriptional regulator
JM964_RS02570	COG0438	transferase activity, transferring glycosyl groups
JM964_RS02585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JM964_RS02590	COG0765	amino acid transport
JM964_RS02595	COG0765	amino acid transport
JM964_RS02600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JM964_RS02610	COG0745	RESPONSE REGULATOR receiver
JM964_RS02620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JM964_RS02625	COG0488	(ABC) transporter
JM964_RS02630	COG0768	penicillin binding
JM964_RS02635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JM964_RS02640	COG1181	Belongs to the D-alanine--D-alanine ligase family
JM964_RS02660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JM964_RS02670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JM964_RS02695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JM964_RS02700	COG0513	Belongs to the DEAD box helicase family
JM964_RS02715	COG2827	Endonuclease containing a URI domain
JM964_RS02720	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JM964_RS02740	COG0626	cystathionine gamma-synthase activity
JM964_RS02745	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JM964_RS02750	COG2207	Transcriptional regulator
JM964_RS02760	COG1653	transport
JM964_RS02765	COG1175	transmembrane transport
JM964_RS02770	COG0395	ABC-type sugar transport system, permease component
JM964_RS02780	COG0366	Alpha amylase catalytic
JM964_RS02785	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JM964_RS02800	COG0683	leucine binding
JM964_RS02830	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS02835	COG0517	IMP dehydrogenase activity
JM964_RS02850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JM964_RS02855	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JM964_RS02860	COG0470	DNA polymerase III
JM964_RS02865	COG4467	Involved in initiation control of chromosome replication
JM964_RS02875	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JM964_RS02885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JM964_RS02890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JM964_RS02895	COG1393	Belongs to the ArsC family
JM964_RS02905	COG0708	Exodeoxyribonuclease III
JM964_RS02915	COG0531	amino acid
JM964_RS02955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JM964_RS02955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JM964_RS02985	COG4122	O-methyltransferase activity
JM964_RS02990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JM964_RS03000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JM964_RS03020	COG1476	TRANSCRIPTIONal
JM964_RS03055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JM964_RS03060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JM964_RS03065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JM964_RS03070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JM964_RS03075	COG0372	Belongs to the citrate synthase family
JM964_RS03080	COG0538	isocitrate dehydrogenase activity
JM964_RS03085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM964_RS03120	COG1196	nuclear chromosome segregation
JM964_RS03125	COG0561	phosphatase activity
JM964_RS03130	COG0561	phosphatase activity
JM964_RS03135	COG0552	protein localization to endoplasmic reticulum
JM964_RS03150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JM964_RS03155	COG3689	TIGRFAM TIGR03943 family protein
JM964_RS03160	COG0701	Predicted permease
JM964_RS03175	COG1597	lipid kinase activity
JM964_RS03185	COG0356	it plays a direct role in the translocation of protons across the membrane
JM964_RS03190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JM964_RS03195	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JM964_RS03200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JM964_RS03205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JM964_RS03210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JM964_RS03215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JM964_RS03225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JM964_RS03240	COG2211	Major facilitator Superfamily
JM964_RS03250	COG3250	beta-galactosidase activity
JM964_RS03260	COG0800	Aldolase
JM964_RS03270	COG1312	Catalyzes the dehydration of D-mannonate
JM964_RS03275	COG1028	Short-chain dehydrogenase reductase Sdr
JM964_RS03305	COG0072	phenylalanine-tRNA ligase activity
JM964_RS03305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JM964_RS03330	COG1051	belongs to the nudix hydrolase family
JM964_RS03335	COG0302	gtp cyclohydrolase
JM964_RS03355	COG2610	gluconate transmembrane transporter activity
JM964_RS03365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JM964_RS03370	COG2807	transmembrane transport
JM964_RS03380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JM964_RS03385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JM964_RS03395	COG1234	tRNA 3'-trailer cleavage
JM964_RS03400	COG0300	oxidoreductase activity
JM964_RS03410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JM964_RS03415	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JM964_RS03415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JM964_RS03425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JM964_RS03440	COG2384	SAM-dependent methyltransferase
JM964_RS03445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JM964_RS03455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JM964_RS03470	COG1088	dTDP-glucose 4,6-dehydratase activity
JM964_RS03475	COG1091	dTDP-4-dehydrorhamnose reductase activity
JM964_RS03505	COG1216	Glycosyl transferase, family 2
JM964_RS03505	COG1442	glycosyl transferase family 8
JM964_RS03535	COG1442	glycosyl transferase family 8
JM964_RS03540	COG1442	glycosyl transferase family 8
JM964_RS03540	COG1216	Glycosyl transferase, family 2
JM964_RS03555	COG1216	Glycosyl transferase, family 2
JM964_RS03585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JM964_RS03595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JM964_RS03610	COG1368	sulfuric ester hydrolase activity
JM964_RS03615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JM964_RS03620	COG0710	3-dehydroquinate dehydratase activity
JM964_RS03625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JM964_RS03630	COG0287	Prephenate dehydrogenase
JM964_RS03635	COG3679	Belongs to the UPF0342 family
JM964_RS03640	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS03650	COG3684	Belongs to the aldolase LacD family
JM964_RS03665	COG4120	Belongs to the binding-protein-dependent transport system permease family
JM964_RS03670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JM964_RS03670	COG1116	anion transmembrane transporter activity
JM964_RS03675	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JM964_RS03680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JM964_RS03685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JM964_RS03690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JM964_RS03700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JM964_RS03705	COG0077	Prephenate dehydratase
JM964_RS03715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JM964_RS03730	COG0270	DNA (cytosine-5-)-methyltransferase activity
JM964_RS03795	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS03850	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS03915	COG1475	DNA binding
JM964_RS03920	COG4443	Transcriptional Coactivator p15 (PC4)
JM964_RS03975	COG1396	sequence-specific DNA binding
JM964_RS03980	COG0542	response to heat
JM964_RS03985	COG0613	PHP domain protein
JM964_RS04000	COG3843	relaxase mobilization nuclease domain protein
JM964_RS04025	COG1131	(ABC) transporter
JM964_RS04085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JM964_RS04090	COG4684	Psort location CytoplasmicMembrane, score
JM964_RS04095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JM964_RS04105	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JM964_RS04115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JM964_RS04145	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JM964_RS04150	COG1349	DNA-binding transcription factor activity
JM964_RS04160	COG1447	Phosphotransferase system cellobiose-specific component IIA
JM964_RS04165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JM964_RS04170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JM964_RS04175	COG1882	Formate acetyltransferase
JM964_RS04195	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JM964_RS04200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JM964_RS04205	COG0446	pyridine nucleotide-disulphide oxidoreductase
JM964_RS04215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JM964_RS04220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JM964_RS04225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JM964_RS04230	COG0346	lactoylglutathione lyase activity
JM964_RS04240	COG1164	Oligoendopeptidase f
JM964_RS04255	COG0210	DNA helicase
JM964_RS04265	COG1011	Hydrolase
JM964_RS04295	COG1131	(ABC) transporter
JM964_RS04325	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JM964_RS04330	COG1074	ATP-dependent DNA helicase activity
JM964_RS04340	COG0187	DNA topoisomerase II activity
JM964_RS04345	COG2184	nucleotidyltransferase activity
JM964_RS04355	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JM964_RS04365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JM964_RS04385	COG0539	negative regulation of cytoplasmic translation
JM964_RS04455	COG1104	cysteine desulfurase activity
JM964_RS04460	COG0301	tRNA thio-modification
JM964_RS04465	COG1114	Component of the transport system for branched-chain amino acids
JM964_RS04470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JM964_RS04475	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JM964_RS04495	COG0564	pseudouridine synthase activity
JM964_RS04500	COG2824	Alkylphosphonate utilization operon protein PhnA
JM964_RS04510	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JM964_RS04515	COG0540	Belongs to the ATCase OTCase family
JM964_RS04520	COG0505	Belongs to the CarA family
JM964_RS04535	COG2136	Putative SAM-dependent methyltransferase
JM964_RS04535	COG2521	methyltransferase
JM964_RS04540	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JM964_RS04555	COG0228	four-way junction DNA binding
JM964_RS04570	COG1132	(ABC) transporter
JM964_RS04575	COG0726	polysaccharide deacetylase
JM964_RS04580	COG0460	homoserine dehydrogenase
JM964_RS04585	COG0083	homoserine kinase activity
JM964_RS04590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JM964_RS04600	COG1176	ABC-type spermidine putrescine transport system, permease component I
JM964_RS04605	COG1177	transmembrane transport
JM964_RS04620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JM964_RS04625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JM964_RS04635	COG0534	Mate efflux family protein
JM964_RS04640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JM964_RS04645	COG0336	Belongs to the RNA methyltransferase TrmD family
JM964_RS04650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JM964_RS04655	COG1349	DNA-binding transcription factor activity
JM964_RS04660	COG1105	Belongs to the carbohydrate kinase PfkB family
JM964_RS04665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM964_RS04665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JM964_RS04665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JM964_RS04675	COG1307	EDD domain protein, DegV family
JM964_RS04680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JM964_RS04685	COG0617	tRNA 3'-terminal CCA addition
JM964_RS04690	COG0488	(ABC) transporter
JM964_RS04700	COG1940	carbohydrate kinase activity
JM964_RS04715	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JM964_RS04720	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JM964_RS04725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JM964_RS04740	COG0481	GTPase activity
JM964_RS04765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JM964_RS04770	COG2890	protein-(glutamine-N5) methyltransferase activity
JM964_RS04775	COG0009	L-threonylcarbamoyladenylate synthase
JM964_RS04785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JM964_RS04795	COG0741	lytic transglycosylase activity
JM964_RS04800	COG4221	oxidoreductase activity
JM964_RS04825	COG1401	restriction endodeoxyribonuclease activity
JM964_RS04830	COG4268	DNA restriction-modification system
JM964_RS04840	COG2188	Transcriptional regulator
JM964_RS04845	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JM964_RS04850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JM964_RS04865	COG1660	Displays ATPase and GTPase activities
JM964_RS04870	COG4974	Belongs to the 'phage' integrase family
JM964_RS04885	COG0745	RESPONSE REGULATOR receiver
JM964_RS04900	COG0577	efflux transmembrane transporter activity
JM964_RS04905	COG1136	(ABC) transporter
JM964_RS04945	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JM964_RS04950	COG0647	UMP catabolic process
JM964_RS04955	COG0222	ribosome binding
JM964_RS04960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JM964_RS04965	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS04970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JM964_RS04975	COG0758	DNA mediated transformation
JM964_RS04980	COG0110	maltose O-acetyltransferase activity
JM964_RS04985	COG1937	Protein conserved in bacteria
JM964_RS04990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JM964_RS04995	COG0446	pyridine nucleotide-disulphide oxidoreductase
JM964_RS05005	COG1272	protein, Hemolysin III
JM964_RS05015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JM964_RS05020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JM964_RS05030	COG0424	maF-like protein
JM964_RS05035	COG0737	Belongs to the 5'-nucleotidase family
JM964_RS05045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JM964_RS05050	COG0463	Glycosyl transferase, family 2
JM964_RS05065	COG0284	orotidine-5'-phosphate decarboxylase activity
JM964_RS05070	COG0167	dihydroorotate dehydrogenase activity
JM964_RS05085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JM964_RS05095	COG0297	glycogen (starch) synthase activity
JM964_RS05105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JM964_RS05110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JM964_RS05140	COG4869	propanediol catabolic process
JM964_RS05145	COG1454	alcohol dehydrogenase
JM964_RS05145	COG1012	belongs to the aldehyde dehydrogenase family
JM964_RS05155	COG4766	ethanolamine catabolic process
JM964_RS05160	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
JM964_RS05190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JM964_RS05195	COG1882	Formate acetyltransferase
JM964_RS05200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JM964_RS05205	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
JM964_RS05210	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
JM964_RS05230	COG4978	Transcriptional regulator
JM964_RS05230	COG0789	Transcriptional regulator
JM964_RS05245	COG3583	domain protein
JM964_RS05260	COG1126	abc transporter atp-binding protein
JM964_RS05270	COG0488	(ABC) transporter
JM964_RS05275	COG2873	o-acetylhomoserine
JM964_RS05305	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JM964_RS05305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JM964_RS05315	COG3711	transcriptional antiterminator
JM964_RS05320	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS05330	COG3775	system Galactitol-specific IIC component
JM964_RS05350	COG1105	Belongs to the carbohydrate kinase PfkB family
JM964_RS05355	COG0698	ribose 5-phosphate isomerase
JM964_RS05360	COG0698	ribose 5-phosphate isomerase
JM964_RS05365	COG1349	DNA-binding transcription factor activity
JM964_RS05375	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS05395	COG1396	sequence-specific DNA binding
JM964_RS05400	COG1194	a g-specific adenine glycosylase
JM964_RS05410	COG1132	(ABC) transporter
JM964_RS05415	COG1132	(ABC) transporter
JM964_RS05420	COG0280	phosphate acetyltransferase
JM964_RS05425	COG0564	pseudouridine synthase activity
JM964_RS05430	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JM964_RS05435	COG2357	RelA SpoT domain protein
JM964_RS05440	COG4116	CYTH
JM964_RS05450	COG1104	cysteine desulfurase activity
JM964_RS05465	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JM964_RS05470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JM964_RS05480	COG3764	Sortase (surface protein transpeptidase)
JM964_RS05485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JM964_RS05490	COG0039	L-malate dehydrogenase activity
JM964_RS05495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JM964_RS05500	COG1079	Belongs to the binding-protein-dependent transport system permease family
JM964_RS05505	COG4603	Belongs to the binding-protein-dependent transport system permease family
JM964_RS05510	COG3845	ABC transporter
JM964_RS05515	COG1744	ABC transporter substrate-binding protein PnrA-like
JM964_RS05520	COG0295	cytidine deaminase activity
JM964_RS05530	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JM964_RS05535	COG2813	Specifically methylates the guanine in position
JM964_RS05540	COG1072	(Pantothenic acid kinase))
JM964_RS05545	COG0268	Binds directly to 16S ribosomal RNA
JM964_RS05555	COG5002	protein histidine kinase activity
JM964_RS05560	COG0745	RESPONSE REGULATOR receiver
JM964_RS05570	COG0704	Plays a role in the regulation of phosphate uptake
JM964_RS05575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JM964_RS05580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JM964_RS05585	COG0581	inorganic phosphate transmembrane transporter activity
JM964_RS05590	COG0573	inorganic phosphate transmembrane transporter activity
JM964_RS05605	COG0483	inositol monophosphate 1-phosphatase activity
JM964_RS05610	COG4476	Belongs to the UPF0223 family
JM964_RS05615	COG1393	Belongs to the ArsC family
JM964_RS05620	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS05625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JM964_RS05630	COG0196	riboflavin kinase activity
JM964_RS05635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JM964_RS05670	COG0561	phosphatase activity
JM964_RS05675	COG2195	Cleaves the N-terminal amino acid of tripeptides
JM964_RS05700	COG3759	membrane
JM964_RS05705	COG1846	Transcriptional regulator
JM964_RS05720	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JM964_RS05725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JM964_RS05730	COG1126	abc transporter atp-binding protein
JM964_RS05735	COG0765	amino acid transport
JM964_RS05740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JM964_RS05750	COG2755	lipolytic protein G-D-S-L family
JM964_RS05750	COG0657	acetylesterase activity
JM964_RS05755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JM964_RS05780	COG0469	pyruvate kinase activity
JM964_RS05785	COG0205	6-phosphofructokinase activity
JM964_RS05795	COG2188	Transcriptional regulator
JM964_RS05800	COG1131	(ABC) transporter
JM964_RS05810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JM964_RS05850	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JM964_RS05855	COG1982	Orn Lys Arg decarboxylase major
JM964_RS05860	COG2151	metal-sulfur cluster biosynthetic enzyme
JM964_RS05865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JM964_RS05870	COG0358	DNA primase activity
JM964_RS05875	COG1970	mechanosensitive ion channel activity
JM964_RS05880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JM964_RS05885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JM964_RS05895	COG0647	UMP catabolic process
JM964_RS05900	COG1051	belongs to the nudix hydrolase family
JM964_RS05910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JM964_RS05920	COG0058	SHG alpha-glucan phosphorylase activity
JM964_RS05925	COG0813	purine-nucleoside phosphorylase activity
JM964_RS05935	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JM964_RS05940	COG1393	Belongs to the ArsC family
JM964_RS05945	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JM964_RS05950	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JM964_RS05955	COG1204	response to ionizing radiation
JM964_RS05965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JM964_RS05980	COG2268	Band 7 protein
JM964_RS05985	COG1704	LemA family
JM964_RS05995	COG1573	uracil-dna glycosylase
JM964_RS06020	COG2226	methyltransferase
JM964_RS06025	COG0488	(ABC) transporter
JM964_RS06030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JM964_RS06045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JM964_RS06050	COG3442	glutamine amidotransferase
JM964_RS06055	COG2226	methyltransferase
JM964_RS06065	COG0488	(ABC) transporter
JM964_RS06110	COG3842	ATPase activity
JM964_RS06125	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JM964_RS06130	COG3527	Alpha-acetolactate decarboxylase
JM964_RS06140	COG0628	permease
JM964_RS06145	COG2706	6-phosphogluconolactonase activity
JM964_RS06155	COG1011	Hydrolase
JM964_RS06195	COG0560	Phosphoserine phosphatase
JM964_RS06200	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JM964_RS06205	COG0187	DNA topoisomerase II activity
JM964_RS06210	COG0693	protein deglycase activity
JM964_RS06215	COG0772	Belongs to the SEDS family
JM964_RS06230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JM964_RS06235	COG0716	FMN binding
JM964_RS06245	COG1605	Chorismate mutase
JM964_RS06245	COG0287	Prephenate dehydrogenase
JM964_RS06250	COG0038	chloride channel
JM964_RS06260	COG0737	Belongs to the 5'-nucleotidase family
JM964_RS06265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JM964_RS06270	COG1466	dna polymerase III delta subunit
JM964_RS06275	COG0658	competence protein
JM964_RS06275	COG2333	competence protein COMEC
JM964_RS06280	COG1596	polysaccharide export
JM964_RS06280	COG1555	photosystem II stabilization
JM964_RS06285	COG0204	Acyl-transferase
JM964_RS06290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JM964_RS06295	COG1120	ATPase activity
JM964_RS06300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JM964_RS06305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JM964_RS06310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JM964_RS06315	COG0386	Belongs to the glutathione peroxidase family
JM964_RS06320	COG1187	pseudouridine synthase activity
JM964_RS06325	COG0435	Glutathione S-transferase
JM964_RS06335	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JM964_RS06340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JM964_RS06345	COG1696	Membrane protein involved in D-alanine export
JM964_RS06370	COG0363	glucosamine-6-phosphate deaminase activity
JM964_RS06375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JM964_RS06380	COG1438	arginine binding
JM964_RS06385	COG3583	domain protein
JM964_RS06385	COG3064	Membrane
JM964_RS06385	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JM964_RS06390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JM964_RS06395	COG1288	antiporter activity
JM964_RS06400	COG0549	Belongs to the carbamate kinase family
JM964_RS06405	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JM964_RS06410	COG0454	-acetyltransferase
JM964_RS06425	COG1481	regulation of sporulation
JM964_RS06430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JM964_RS06435	COG1660	Displays ATPase and GTPase activities
JM964_RS06440	COG0251	oxidation-reduction process
JM964_RS06445	COG0534	Mate efflux family protein
JM964_RS06455	COG0436	Aminotransferase
JM964_RS06470	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JM964_RS06475	COG0562	UDP-galactopyranose mutase
JM964_RS06490	COG1216	Glycosyl transferase, family 2
JM964_RS06510	COG0110	maltose O-acetyltransferase activity
JM964_RS06525	COG1216	Glycosyl transferase, family 2
JM964_RS06530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JM964_RS06535	COG3177	Filamentation induced by cAMP protein fic
JM964_RS06545	COG4464	protein tyrosine phosphatase activity
JM964_RS06555	COG3944	biosynthesis protein
JM964_RS06560	COG1316	TRANSCRIPTIONal
JM964_RS06565	COG3022	response to hydroperoxide
JM964_RS06570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JM964_RS06585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JM964_RS06590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JM964_RS06595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JM964_RS06620	COG1702	phosphate starvation-inducible protein PhoH
JM964_RS06625	COG4479	Belongs to the UPF0346 family
JM964_RS06640	COG2996	Protein conserved in bacteria
JM964_RS06645	COG0233	cytoplasmic translational termination
JM964_RS06650	COG0528	UMP kinase activity
JM964_RS06655	COG2244	polysaccharide biosynthetic process
JM964_RS06660	COG0625	glutathione transferase activity
JM964_RS06685	COG0346	lactoylglutathione lyase activity
JM964_RS06690	COG0697	spore germination
JM964_RS06690	COG1674	ftsk spoiiie
JM964_RS06695	COG1621	beta-fructofuranosidase activity
JM964_RS06700	COG1653	transport
JM964_RS06705	COG0395	ABC-type sugar transport system, permease component
JM964_RS06710	COG4209	transmembrane transport
JM964_RS06715	COG1609	Transcriptional regulator
JM964_RS06735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JM964_RS06775	COG0494	nUDIX hydrolase
JM964_RS06780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JM964_RS06795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JM964_RS06800	COG1028	Short-chain dehydrogenase reductase Sdr
JM964_RS06825	COG0577	efflux transmembrane transporter activity
JM964_RS06830	COG1136	(ABC) transporter
JM964_RS06835	COG2205	protein histidine kinase activity
JM964_RS06850	COG0436	Aminotransferase
JM964_RS06865	COG1131	(ABC) transporter
JM964_RS06875	COG1309	transcriptional regulator
JM964_RS06885	COG1174	glycine betaine transport
JM964_RS06890	COG0517	IMP dehydrogenase activity
JM964_RS06890	COG1125	glycine betaine transport
JM964_RS06915	COG1733	regulation of RNA biosynthetic process
JM964_RS06930	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JM964_RS06935	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JM964_RS06940	COG1482	cell wall glycoprotein biosynthetic process
JM964_RS06955	COG3091	SprT-like family
JM964_RS06960	COG2183	response to ionizing radiation
JM964_RS06965	COG0656	L-ascorbic acid biosynthetic process
JM964_RS06970	COG4708	membrane
JM964_RS06975	COG2246	polysaccharide biosynthetic process
JM964_RS06990	COG0024	Methionine aminopeptidase
JM964_RS07000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JM964_RS07005	COG2249	NAD(P)H dehydrogenase (quinone) activity
JM964_RS07010	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JM964_RS07015	COG2131	deaminase
JM964_RS07035	COG1363	Peptidase, m42
JM964_RS07050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JM964_RS07055	COG1956	GAF domain-containing protein
JM964_RS07065	COG1695	Transcriptional regulator
JM964_RS07075	COG0673	inositol 2-dehydrogenase activity
JM964_RS07080	COG0513	Belongs to the DEAD box helicase family
JM964_RS07085	COG0726	polysaccharide deacetylase
JM964_RS07100	COG0183	Belongs to the thiolase family
JM964_RS07105	COG3425	synthase
JM964_RS07120	COG0776	regulation of translation
JM964_RS07130	COG2755	lipolytic protein G-D-S-L family
JM964_RS07135	COG1307	EDD domain protein, DegV family
JM964_RS07140	COG0497	DNA recombination
JM964_RS07145	COG1438	arginine binding
JM964_RS07150	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JM964_RS07160	COG1722	exodeoxyribonuclease VII activity
JM964_RS07165	COG1570	exodeoxyribonuclease VII activity
JM964_RS07170	COG2321	neutral zinc metallopeptidase
JM964_RS07195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JM964_RS07205	COG0765	amino acid transport
JM964_RS07210	COG4703	Protein of unknown function (DUF1797)
JM964_RS07215	COG0542	response to heat
JM964_RS07220	COG0406	alpha-ribazole phosphatase activity
JM964_RS07220	COG0494	nUDIX hydrolase
JM964_RS07240	COG3599	regulation of cell shape
JM964_RS07255	COG1799	cell septum assembly
JM964_RS07260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JM964_RS07280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JM964_RS07295	COG1217	gtp-binding protein TYPA
JM964_RS07350	COG0346	lactoylglutathione lyase activity
JM964_RS07365	COG2017	converts alpha-aldose to the beta-anomer
JM964_RS07375	COG3716	PTS system mannose fructose sorbose family IID component
JM964_RS07385	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JM964_RS07395	COG2188	Transcriptional regulator
JM964_RS07455	COG2188	Transcriptional regulator
JM964_RS07465	COG3557	Belongs to the UPF0374 family
JM964_RS07475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JM964_RS07505	COG2132	Multicopper oxidase
JM964_RS07515	COG2217	Heavy metal translocating P-type atpase
JM964_RS07605	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JM964_RS07610	COG1739	Uncharacterized protein family UPF0029
JM964_RS07620	COG1098	S1 RNA binding domain
JM964_RS07645	COG2815	serine threonine protein kinase
JM964_RS07645	COG0515	serine threonine protein kinase
JM964_RS07650	COG0631	protein serine/threonine phosphatase activity
JM964_RS07655	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JM964_RS07655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JM964_RS07660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JM964_RS07665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JM964_RS07670	COG1758	RNA polymerase activity
JM964_RS07680	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS07685	COG1119	ATPase activity
JM964_RS07690	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JM964_RS07710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JM964_RS07715	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JM964_RS07720	COG0133	tryptophan synthase activity
JM964_RS07735	COG4470	Protein conserved in bacteria
JM964_RS07740	COG3480	Lon protease (S16) C-terminal proteolytic domain
JM964_RS07745	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JM964_RS07750	COG0742	ribosomal rna small subunit methyltransferase
JM964_RS07760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JM964_RS07765	COG4483	Protein conserved in bacteria
JM964_RS07770	COG2197	response regulator
JM964_RS07775	COG4585	Histidine kinase
JM964_RS07780	COG0842	Transport permease protein
JM964_RS07785	COG1131	(ABC) transporter
JM964_RS07800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JM964_RS07810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JM964_RS07810	COG2755	lipolytic protein G-D-S-L family
JM964_RS07815	COG0671	phosphoesterase, PA-phosphatase related
JM964_RS07820	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JM964_RS07830	COG0747	negative chemotaxis
JM964_RS07835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JM964_RS07840	COG1187	pseudouridine synthase activity
JM964_RS07845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JM964_RS07850	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JM964_RS07855	COG0582	viral genome integration into host DNA
JM964_RS07875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JM964_RS07880	COG3763	UPF0154 protein
JM964_RS07890	COG3579	cysteine-type endopeptidase activity
JM964_RS07905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JM964_RS07910	COG1254	Belongs to the acylphosphatase family
JM964_RS07920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JM964_RS07925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JM964_RS07935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JM964_RS07945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JM964_RS07960	COG1160	GTP binding
JM964_RS07970	COG1484	DNA-dependent DNA replication
JM964_RS07980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JM964_RS07985	COG0628	permease
JM964_RS07990	COG0745	RESPONSE REGULATOR receiver
JM964_RS07995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JM964_RS08005	COG0492	ferredoxin-NADP+ reductase activity
JM964_RS08015	COG0513	Belongs to the DEAD box helicase family
JM964_RS08025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JM964_RS08030	COG0768	penicillin binding
JM964_RS08040	COG0275	rRNA processing
JM964_RS08085	COG4939	FMN-binding domain protein
JM964_RS08090	COG0142	geranyltranstransferase activity
JM964_RS08095	COG1252	NADH dehydrogenase
JM964_RS08105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JM964_RS08110	COG0569	domain protein
JM964_RS08115	COG0534	Mate efflux family protein
JM964_RS08125	COG4224	UPF0291 protein
JM964_RS08130	COG0751	glycine-tRNA ligase activity
JM964_RS08155	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JM964_RS08160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JM964_RS08165	COG1464	Belongs to the NlpA lipoprotein family
JM964_RS08170	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JM964_RS08175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JM964_RS08180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JM964_RS08185	COG2252	PERMEase
JM964_RS08190	COG0561	phosphatase activity
JM964_RS08200	COG3715	PTS system
JM964_RS08205	COG3716	PTS system mannose fructose sorbose family IID component
JM964_RS08220	COG1983	PspC domain protein
JM964_RS08225	COG1266	CAAX protease self-immunity
JM964_RS08245	COG0439	Biotin carboxylase
JM964_RS08265	COG1028	Short-chain dehydrogenase reductase Sdr
JM964_RS08270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JM964_RS08275	COG2070	2-Nitropropane dioxygenase
JM964_RS08285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JM964_RS08295	COG1024	Enoyl-CoA hydratase
JM964_RS08300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JM964_RS08305	COG0527	aspartate kinase activity
JM964_RS08310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JM964_RS08315	COG0736	holo-[acyl-carrier-protein] synthase activity
JM964_RS08320	COG0653	protein targeting
JM964_RS08325	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS08330	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS08335	COG3583	domain protein
JM964_RS08335	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JM964_RS08340	COG1940	carbohydrate kinase activity
JM964_RS08345	COG1263	PTS System
JM964_RS08345	COG2190	(PTS) system
JM964_RS08345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JM964_RS08350	COG1621	beta-fructofuranosidase activity
JM964_RS08355	COG1609	Transcriptional regulator
JM964_RS08360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JM964_RS08375	COG0006	proline dipeptidase activity
JM964_RS08400	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JM964_RS08415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JM964_RS08420	COG0629	single-stranded DNA binding
JM964_RS08430	COG0095	Lipoate-protein ligase
JM964_RS08435	COG2723	6-phospho-beta-galactosidase activity
JM964_RS08450	COG2723	6-phospho-beta-galactosidase activity
JM964_RS08455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JM964_RS08465	COG1447	Phosphotransferase system cellobiose-specific component IIA
JM964_RS08470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JM964_RS08470	COG3711	transcriptional antiterminator
JM964_RS08485	COG4095	Psort location CytoplasmicMembrane, score
JM964_RS08490	COG2723	6-phospho-beta-galactosidase activity
JM964_RS08495	COG2723	6-phospho-beta-galactosidase activity
JM964_RS08505	COG1917	Cupin 2, conserved barrel domain protein
JM964_RS08505	COG2207	Transcriptional regulator
JM964_RS08515	COG1263	PTS System
JM964_RS08515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JM964_RS08515	COG2190	(PTS) system
JM964_RS08520	COG3711	transcriptional antiterminator
JM964_RS08535	COG0508	dehydrogenase complex catalyzes the overall conversion of
JM964_RS08540	COG0508	dehydrogenase complex catalyzes the overall conversion of
JM964_RS08540	COG0022	dehydrogenase e1 component
JM964_RS08545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JM964_RS08550	COG2860	membrane
JM964_RS08565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JM964_RS08570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JM964_RS08580	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JM964_RS08585	COG0195	Participates in both transcription termination and antitermination
JM964_RS08595	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JM964_RS08605	COG4473	ABC transporter
JM964_RS08610	COG1131	(ABC) transporter
JM964_RS08615	COG0537	adenosine 5'-monophosphoramidase activity
JM964_RS08625	COG1316	TRANSCRIPTIONal
JM964_RS08635	COG0802	atpase or kinase
JM964_RS08640	COG1461	Dihydroxyacetone kinase
JM964_RS08650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JM964_RS08655	COG0601	transmembrane transport
JM964_RS08660	COG4608	Belongs to the ABC transporter superfamily
JM964_RS08675	COG1686	Belongs to the peptidase S11 family
JM964_RS08690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JM964_RS08695	COG0719	Fe-S assembly protein
JM964_RS08705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JM964_RS08710	COG4862	establishment of competence for transformation
JM964_RS08715	COG1968	undecaprenyl-diphosphatase activity
JM964_RS08720	COG0765	amino acid transport
JM964_RS08740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JM964_RS08745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JM964_RS08750	COG0440	acetolactate synthase activity
JM964_RS08755	COG0028	Belongs to the TPP enzyme family
JM964_RS08760	COG0463	Glycosyl transferase, family 2
JM964_RS08770	COG0129	dihydroxy-acid dehydratase activity
JM964_RS08780	COG2151	metal-sulfur cluster biosynthetic enzyme
JM964_RS08840	COG1442	glycosyl transferase family 8
JM964_RS08840	COG1216	Glycosyl transferase, family 2
JM964_RS08855	COG1442	glycosyl transferase family 8
JM964_RS08855	COG1216	Glycosyl transferase, family 2
JM964_RS08865	COG1442	glycosyl transferase family 8
JM964_RS08910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JM964_RS08930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JM964_RS08965	COG2207	Transcriptional regulator
JM964_RS08965	COG4753	response regulator
JM964_RS08970	COG2972	Histidine kinase
JM964_RS08980	COG1653	transport
JM964_RS08985	COG0395	ABC-type sugar transport system, permease component
JM964_RS08990	COG1175	transmembrane transport
JM964_RS09005	COG0383	alpha-mannosidase activity
JM964_RS09025	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JM964_RS09045	COG1045	serine acetyltransferase
JM964_RS09050	COG1185	polyribonucleotide nucleotidyltransferase activity
JM964_RS09055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JM964_RS09085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JM964_RS09090	COG1187	pseudouridine synthase activity
JM964_RS09110	COG0242	peptide deformylase activity
JM964_RS09140	COG0066	3-isopropylmalate dehydratase activity
JM964_RS09165	COG2309	aminopeptidase activity
JM964_RS09175	COG2176	DNA-directed DNA polymerase activity
JM964_RS09195	COG2376	Dihydroxyacetone kinase
JM964_RS09205	COG2376	Dihydroxyacetone kinase
JM964_RS09210	COG1461	Dihydroxyacetone kinase
JM964_RS09215	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JM964_RS09220	COG0442	prolyl-tRNA aminoacylation
JM964_RS09230	COG4589	Belongs to the CDS family
JM964_RS09235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JM964_RS09240	COG1862	Preprotein translocase
JM964_RS09250	COG1181	Belongs to the D-alanine--D-alanine ligase family
JM964_RS09250	COG2918	glutathione biosynthetic process
JM964_RS09260	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JM964_RS09265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JM964_RS09270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JM964_RS09275	COG0542	response to heat
JM964_RS09280	COG4463	regulation of RNA biosynthetic process
JM964_RS09295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JM964_RS09335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JM964_RS09340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JM964_RS09345	COG0492	ferredoxin-NADP+ reductase activity
JM964_RS09350	COG0564	pseudouridine synthase activity
JM964_RS09355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JM964_RS09375	COG1564	THIamine pyrophosphokinase
JM964_RS09385	COG1162	GTPase activity
JM964_RS09395	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JM964_RS09400	COG1132	(ABC) transporter
JM964_RS09450	COG0084	hydrolase, TatD family'
JM964_RS09460	COG1847	R3H domain protein
JM964_RS09470	COG0594	ribonuclease P activity
JM964_RS09475	COG0165	Argininosuccinate lyase
JM964_RS09480	COG0137	argininosuccinate synthase activity
JM964_RS09490	COG1827	regulation of RNA biosynthetic process
JM964_RS09505	COG2040	homocysteine
JM964_RS09510	COG0833	amino acid
JM964_RS09520	COG2826	transposase and inactivated derivatives, IS30 family
JM964_RS09550	COG1442	glycosyl transferase family 8
JM964_RS09575	COG0756	dUTP diphosphatase activity
JM964_RS09580	COG1132	(ABC) transporter
JM964_RS09585	COG1132	(ABC) transporter
JM964_RS09595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JM964_RS09600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JM964_RS09605	COG0705	Rhomboid family
JM964_RS09610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JM964_RS09615	COG1473	amidohydrolase
JM964_RS09620	COG2171	N-acyltransferase activity
JM964_RS09630	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JM964_RS09645	COG1442	glycosyl transferase family 8
JM964_RS09665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JM964_RS09690	COG3623	hexulose-6-phosphate isomerase
JM964_RS09715	COG1523	belongs to the glycosyl hydrolase 13 family
JM964_RS09720	COG1609	Transcriptional regulator
JM964_RS09725	COG1126	abc transporter atp-binding protein
JM964_RS09730	COG0765	amino acid transport
JM964_RS09735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JM964_RS09745	COG3942	CHAP domain
JM964_RS09755	COG4667	esterase of the alpha-beta hydrolase superfamily
JM964_RS09760	COG3590	peptidase
JM964_RS09765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JM964_RS09770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JM964_RS09770	COG1321	iron dependent repressor
JM964_RS09775	COG1121	(ABC) transporter
JM964_RS09780	COG0803	Belongs to the bacterial solute-binding protein 9 family
JM964_RS09795	COG1490	D-aminoacyl-tRNA deacylase activity
JM964_RS09805	COG0737	Belongs to the 5'-nucleotidase family
JM964_RS09815	COG1811	Na channel or pump
JM964_RS09820	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JM964_RS09845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JM964_RS09870	COG0737	Belongs to the 5'-nucleotidase family
JM964_RS09880	COG1328	CTP reductase activity
JM964_RS09885	COG1126	abc transporter atp-binding protein
JM964_RS09895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JM964_RS09900	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JM964_RS09920	COG1438	arginine binding
JM964_RS09925	COG0018	arginyl-trna synthetase
JM964_RS09945	COG1640	4-alpha-glucanotransferase
JM964_RS09950	COG2182	Extracellular solute-binding protein
JM964_RS09955	COG1175	transmembrane transport
JM964_RS09960	COG3833	ABC-type maltose transport systems, permease component
JM964_RS09965	COG5521	maltodextrose utilization protein MalA
JM964_RS09970	COG1609	Transcriptional regulator
JM964_RS09975	COG1523	belongs to the glycosyl hydrolase 13 family
JM964_RS09980	COG1780	Probably involved in ribonucleotide reductase function
JM964_RS09985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JM964_RS09990	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JM964_RS09995	COG2153	protein acetylation
JM964_RS10000	COG4989	oxidoreductase activity
JM964_RS10005	COG1216	Glycosyl transferase, family 2
JM964_RS10010	COG1472	Belongs to the glycosyl hydrolase 3 family
JM964_RS10055	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JM964_RS10065	COG0305	Participates in initiation and elongation during chromosome replication
JM964_RS10070	COG0359	binds to the 23S rRNA
JM964_RS10080	COG0445	tRNA wobble uridine modification
JM964_RS10085	COG0494	nUDIX hydrolase
JM964_RS10090	COG1733	regulation of RNA biosynthetic process
JM964_RS10100	COG0482	sulfurtransferase activity
JM964_RS10105	COG1760	l-serine dehydratase
JM964_RS10110	COG1760	l-serine dehydratase
JM964_RS10120	COG0745	RESPONSE REGULATOR receiver
JM964_RS10125	COG5002	protein histidine kinase activity
JM964_RS10125	COG3850	Histidine kinase
JM964_RS10135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JM964_RS10140	COG1122	ATPase activity
JM964_RS10145	COG1122	ATPase activity
JM964_RS10150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JM964_RS10155	COG1426	Protein conserved in bacteria
JM964_RS10160	COG0612	Peptidase, M16
JM964_RS10165	COG0612	Peptidase, M16
JM964_RS10175	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JM964_RS10180	COG0517	IMP dehydrogenase activity
JM964_RS10180	COG0516	GMP reductase activity
JM964_RS10190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JM964_RS10195	COG0488	(ABC) transporter
JM964_RS10225	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JM964_RS10230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JM964_RS10235	COG1475	DNA binding