locus-tag	class	description
DK875_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DK875_RS00010	COG0592	DNA-directed DNA polymerase activity
DK875_RS00030	COG0012	GTP binding
DK875_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
DK875_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DK875_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DK875_RS00060	COG0037	tRNA processing
DK875_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DK875_RS00150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK875_RS00160	COG3557	Belongs to the UPF0374 family
DK875_RS00170	COG2188	Transcriptional regulator
DK875_RS00175	COG2188	Transcriptional regulator
DK875_RS00185	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK875_RS00195	COG3716	PTS system mannose fructose sorbose family IID component
DK875_RS00205	COG2017	converts alpha-aldose to the beta-anomer
DK875_RS00220	COG0346	lactoylglutathione lyase activity
DK875_RS00255	COG0494	nUDIX hydrolase
DK875_RS00285	COG0681	Belongs to the peptidase S26 family
DK875_RS00300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DK875_RS00305	COG0632	four-way junction helicase activity
DK875_RS00310	COG0519	Catalyzes the synthesis of GMP from XMP
DK875_RS00325	COG1393	Belongs to the ArsC family
DK875_RS00330	COG4472	Bacterial protein of unknown function (DUF965)
DK875_RS00335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DK875_RS00340	COG3906	Belongs to the UPF0473 family
DK875_RS00355	COG0051	transcription antitermination factor activity, RNA binding
DK875_RS00360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DK875_RS00365	COG0088	Forms part of the polypeptide exit tunnel
DK875_RS00370	COG0089	rRNA binding
DK875_RS00375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DK875_RS00380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DK875_RS00385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DK875_RS00390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DK875_RS00395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DK875_RS00400	COG0255	Belongs to the universal ribosomal protein uL29 family
DK875_RS00405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DK875_RS00410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DK875_RS00415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DK875_RS00420	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DK875_RS00425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DK875_RS00430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DK875_RS00435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DK875_RS00440	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DK875_RS00445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DK875_RS00450	COG1841	ribosomal large subunit assembly
DK875_RS00460	COG0201	protein transport
DK875_RS00465	COG0563	adenylate kinase activity
DK875_RS00470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DK875_RS00475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DK875_RS00480	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DK875_RS00490	COG0202	RNA polymerase activity
DK875_RS00615	COG1792	Involved in formation and maintenance of cell shape
DK875_RS00630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DK875_RS00635	COG0436	Aminotransferase
DK875_RS00640	COG1381	Involved in DNA repair and RecF pathway recombination
DK875_RS00645	COG0416	fatty acid biosynthetic process
DK875_RS00650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK875_RS00660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DK875_RS00675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DK875_RS00680	COG0138	bifunctional purine biosynthesis protein purh
DK875_RS00705	COG0151	Belongs to the GarS family
DK875_RS00710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DK875_RS00725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DK875_RS00755	COG1131	(ABC) transporter
DK875_RS00765	COG1132	(ABC) transporter
DK875_RS00775	COG2255	four-way junction helicase activity
DK875_RS00785	COG0546	phosphoglycolate phosphatase activity
DK875_RS00805	COG1126	abc transporter atp-binding protein
DK875_RS00810	COG1328	CTP reductase activity
DK875_RS00815	COG0737	Belongs to the 5'-nucleotidase family
DK875_RS00840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DK875_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DK875_RS00895	COG1490	D-aminoacyl-tRNA deacylase activity
DK875_RS00915	COG0803	Belongs to the bacterial solute-binding protein 9 family
DK875_RS00925	COG1121	(ABC) transporter
DK875_RS00930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK875_RS00930	COG1321	iron dependent repressor
DK875_RS00935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK875_RS00940	COG3590	peptidase
DK875_RS00950	COG1486	melibiose metabolic process
DK875_RS00955	COG2723	6-phospho-beta-galactosidase activity
DK875_RS00965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK875_RS00965	COG3711	transcriptional antiterminator
DK875_RS00975	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK875_RS00985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK875_RS00990	COG3942	CHAP domain
DK875_RS00995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK875_RS01000	COG0765	amino acid transport
DK875_RS01005	COG1126	abc transporter atp-binding protein
DK875_RS01010	COG1609	Transcriptional regulator
DK875_RS01015	COG1523	belongs to the glycosyl hydrolase 13 family
DK875_RS01040	COG3623	hexulose-6-phosphate isomerase
DK875_RS01065	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DK875_RS01090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DK875_RS01100	COG2171	N-acyltransferase activity
DK875_RS01105	COG1473	amidohydrolase
DK875_RS01110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DK875_RS01115	COG0705	Rhomboid family
DK875_RS01120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DK875_RS01125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DK875_RS01135	COG1132	(ABC) transporter
DK875_RS01140	COG1132	(ABC) transporter
DK875_RS01145	COG0756	dUTP diphosphatase activity
DK875_RS01200	COG1827	regulation of RNA biosynthetic process
DK875_RS01210	COG0137	argininosuccinate synthase activity
DK875_RS01215	COG0165	Argininosuccinate lyase
DK875_RS01220	COG0594	ribonuclease P activity
DK875_RS01230	COG1847	R3H domain protein
DK875_RS01240	COG0084	hydrolase, TatD family'
DK875_RS01265	COG4115	mRNA cleavage
DK875_RS01300	COG1132	(ABC) transporter
DK875_RS01305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DK875_RS01315	COG1162	GTPase activity
DK875_RS01325	COG1564	THIamine pyrophosphokinase
DK875_RS01345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK875_RS01385	COG0564	pseudouridine synthase activity
DK875_RS01390	COG0492	ferredoxin-NADP+ reductase activity
DK875_RS01395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK875_RS01400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK875_RS01435	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DK875_RS01450	COG4463	regulation of RNA biosynthetic process
DK875_RS01455	COG0542	response to heat
DK875_RS01460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DK875_RS01480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DK875_RS01485	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DK875_RS01495	COG2918	glutathione biosynthetic process
DK875_RS01495	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK875_RS01505	COG1862	Preprotein translocase
DK875_RS01510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DK875_RS01515	COG4589	Belongs to the CDS family
DK875_RS01525	COG0442	prolyl-tRNA aminoacylation
DK875_RS01530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DK875_RS01535	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DK875_RS01540	COG1461	Dihydroxyacetone kinase
DK875_RS01545	COG2376	Dihydroxyacetone kinase
DK875_RS01560	COG2376	Dihydroxyacetone kinase
DK875_RS01565	COG2176	DNA-directed DNA polymerase activity
DK875_RS01580	COG2309	aminopeptidase activity
DK875_RS01605	COG0066	3-isopropylmalate dehydratase activity
DK875_RS01615	COG0242	peptide deformylase activity
DK875_RS01635	COG1187	pseudouridine synthase activity
DK875_RS01675	COG1131	(ABC) transporter
DK875_RS01680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DK875_RS01685	COG1185	polyribonucleotide nucleotidyltransferase activity
DK875_RS01690	COG1045	serine acetyltransferase
DK875_RS01710	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DK875_RS01720	COG3842	ATPase activity
DK875_RS01735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK875_RS01750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DK875_RS01810	COG2151	metal-sulfur cluster biosynthetic enzyme
DK875_RS01825	COG0129	dihydroxy-acid dehydratase activity
DK875_RS01835	COG0463	Glycosyl transferase, family 2
DK875_RS01840	COG0028	Belongs to the TPP enzyme family
DK875_RS01845	COG0440	acetolactate synthase activity
DK875_RS01850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DK875_RS01855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DK875_RS01875	COG0765	amino acid transport
DK875_RS01880	COG1968	undecaprenyl-diphosphatase activity
DK875_RS01885	COG4862	establishment of competence for transformation
DK875_RS01890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK875_RS01900	COG0719	Fe-S assembly protein
DK875_RS01905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DK875_RS01920	COG1686	Belongs to the peptidase S11 family
DK875_RS01925	COG0747	negative chemotaxis
DK875_RS01935	COG4608	Belongs to the ABC transporter superfamily
DK875_RS01940	COG0601	transmembrane transport
DK875_RS01945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK875_RS01965	COG0802	atpase or kinase
DK875_RS01975	COG1316	TRANSCRIPTIONal
DK875_RS01985	COG0537	adenosine 5'-monophosphoramidase activity
DK875_RS01990	COG1131	(ABC) transporter
DK875_RS01995	COG4473	ABC transporter
DK875_RS02005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DK875_RS02015	COG0195	Participates in both transcription termination and antitermination
DK875_RS02020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DK875_RS02030	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DK875_RS02035	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DK875_RS02050	COG2860	membrane
DK875_RS02055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DK875_RS02060	COG0022	dehydrogenase e1 component
DK875_RS02060	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK875_RS02065	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK875_RS02085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK875_RS02085	COG1263	PTS System
DK875_RS02085	COG2190	(PTS) system
DK875_RS02100	COG2207	Transcriptional regulator
DK875_RS02105	COG2723	6-phospho-beta-galactosidase activity
DK875_RS02110	COG0346	lactoylglutathione lyase activity
DK875_RS02115	COG2723	6-phospho-beta-galactosidase activity
DK875_RS02120	COG4095	Psort location CytoplasmicMembrane, score
DK875_RS02135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK875_RS02135	COG3711	transcriptional antiterminator
DK875_RS02140	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK875_RS02150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK875_RS02155	COG2723	6-phospho-beta-galactosidase activity
DK875_RS02170	COG2723	6-phospho-beta-galactosidase activity
DK875_RS02175	COG0095	Lipoate-protein ligase
DK875_RS02185	COG0629	single-stranded DNA binding
DK875_RS02190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DK875_RS02205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DK875_RS02210	COG0006	proline dipeptidase activity
DK875_RS02225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK875_RS02230	COG1609	Transcriptional regulator
DK875_RS02235	COG1621	beta-fructofuranosidase activity
DK875_RS02240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK875_RS02240	COG2190	(PTS) system
DK875_RS02240	COG1263	PTS System
DK875_RS02245	COG1940	carbohydrate kinase activity
DK875_RS02255	COG0653	protein targeting
DK875_RS02260	COG0736	holo-[acyl-carrier-protein] synthase activity
DK875_RS02265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DK875_RS02275	COG0527	aspartate kinase activity
DK875_RS02280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DK875_RS02285	COG1024	Enoyl-CoA hydratase
DK875_RS02295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DK875_RS02305	COG2070	2-Nitropropane dioxygenase
DK875_RS02310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DK875_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
DK875_RS02335	COG0439	Biotin carboxylase
DK875_RS02390	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DK875_RS02400	COG3177	Filamentation induced by cAMP protein fic
DK875_RS02425	COG3716	PTS system mannose fructose sorbose family IID component
DK875_RS02430	COG3715	PTS system
DK875_RS02440	COG0561	phosphatase activity
DK875_RS02445	COG2252	PERMEase
DK875_RS02450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DK875_RS02455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK875_RS02465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK875_RS02470	COG1464	Belongs to the NlpA lipoprotein family
DK875_RS02475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK875_RS02480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DK875_RS02505	COG0751	glycine-tRNA ligase activity
DK875_RS02510	COG4224	UPF0291 protein
DK875_RS02520	COG0534	Mate efflux family protein
DK875_RS02525	COG0569	domain protein
DK875_RS02530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DK875_RS02540	COG1252	NADH dehydrogenase
DK875_RS02545	COG0142	geranyltranstransferase activity
DK875_RS02550	COG4939	FMN-binding domain protein
DK875_RS02595	COG0275	rRNA processing
DK875_RS02605	COG0768	penicillin binding
DK875_RS02610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK875_RS02620	COG1132	(ABC) transporter
DK875_RS02625	COG1132	(ABC) transporter
DK875_RS02630	COG1011	Hydrolase
DK875_RS02655	COG1737	Transcriptional regulator
DK875_RS02665	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DK875_RS02670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DK875_RS02675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DK875_RS02680	COG0237	dephospho-CoA kinase activity
DK875_RS02685	COG2814	Major facilitator Superfamily
DK875_RS02690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK875_RS02700	COG0557	exoribonuclease II activity
DK875_RS02705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DK875_RS02710	COG1063	alcohol dehydrogenase
DK875_RS02725	COG2217	Heavy metal translocating P-type atpase
DK875_RS02730	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DK875_RS02740	COG1136	(ABC) transporter
DK875_RS02750	COG3547	Transposase (IS116 IS110 IS902 family)
DK875_RS02760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK875_RS02760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK875_RS02770	COG1832	CoA-binding protein
DK875_RS02780	COG0343	queuine tRNA-ribosyltransferase activity
DK875_RS02790	COG1609	Transcriptional regulator
DK875_RS02805	COG0438	transferase activity, transferring glycosyl groups
DK875_RS02820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DK875_RS02825	COG0765	amino acid transport
DK875_RS02830	COG0765	amino acid transport
DK875_RS02835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK875_RS02845	COG0745	RESPONSE REGULATOR receiver
DK875_RS02855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DK875_RS02865	COG0488	(ABC) transporter
DK875_RS02870	COG0768	penicillin binding
DK875_RS02875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DK875_RS02880	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK875_RS02900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK875_RS02910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DK875_RS02925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DK875_RS02945	COG1609	Transcriptional regulator
DK875_RS02950	COG4209	transmembrane transport
DK875_RS02955	COG0395	ABC-type sugar transport system, permease component
DK875_RS02960	COG1653	transport
DK875_RS02970	COG1674	ftsk spoiiie
DK875_RS02970	COG0697	spore germination
DK875_RS02975	COG0346	lactoylglutathione lyase activity
DK875_RS03000	COG0625	glutathione transferase activity
DK875_RS03005	COG2244	polysaccharide biosynthetic process
DK875_RS03010	COG0528	UMP kinase activity
DK875_RS03015	COG0233	cytoplasmic translational termination
DK875_RS03020	COG2996	Protein conserved in bacteria
DK875_RS03035	COG4479	Belongs to the UPF0346 family
DK875_RS03040	COG1702	phosphate starvation-inducible protein PhoH
DK875_RS03050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK875_RS03055	COG2807	transmembrane transport
DK875_RS03065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DK875_RS03070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DK875_RS03080	COG1234	tRNA 3'-trailer cleavage
DK875_RS03085	COG0300	oxidoreductase activity
DK875_RS03095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DK875_RS03100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DK875_RS03100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DK875_RS03110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK875_RS03125	COG2384	SAM-dependent methyltransferase
DK875_RS03130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DK875_RS03140	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DK875_RS03155	COG1088	dTDP-glucose 4,6-dehydratase activity
DK875_RS03160	COG1091	dTDP-4-dehydrorhamnose reductase activity
DK875_RS03190	COG0463	Glycosyl transferase, family 2
DK875_RS03220	COG1442	glycosyl transferase family 8
DK875_RS03225	COG1442	glycosyl transferase family 8
DK875_RS03225	COG1216	Glycosyl transferase, family 2
DK875_RS03240	COG1216	Glycosyl transferase, family 2
DK875_RS03270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DK875_RS03280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DK875_RS03295	COG1368	sulfuric ester hydrolase activity
DK875_RS03300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DK875_RS03305	COG0710	3-dehydroquinate dehydratase activity
DK875_RS03310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DK875_RS03315	COG0287	Prephenate dehydrogenase
DK875_RS03320	COG3679	Belongs to the UPF0342 family
DK875_RS03330	COG3142	Participates in the control of copper homeostasis
DK875_RS03345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK875_RS03350	COG1534	Rna-binding protein
DK875_RS03355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DK875_RS03360	COG1713	HD superfamily hydrolase involved in NAD metabolism
DK875_RS03375	COG0799	negative regulation of ribosome biogenesis
DK875_RS03380	COG2226	methyltransferase
DK875_RS03420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DK875_RS03425	COG0077	Prephenate dehydratase
DK875_RS03435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK875_RS03445	COG0562	UDP-galactopyranose mutase
DK875_RS03455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DK875_RS03470	COG0436	Aminotransferase
DK875_RS03490	COG0534	Mate efflux family protein
DK875_RS03495	COG0251	oxidation-reduction process
DK875_RS03500	COG1660	Displays ATPase and GTPase activities
DK875_RS03505	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DK875_RS03510	COG1481	regulation of sporulation
DK875_RS03525	COG0454	-acetyltransferase
DK875_RS03530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DK875_RS03535	COG0549	Belongs to the carbamate kinase family
DK875_RS03540	COG1288	antiporter activity
DK875_RS03545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK875_RS03550	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DK875_RS03550	COG3064	Membrane
DK875_RS03550	COG3583	domain protein
DK875_RS03555	COG1438	arginine binding
DK875_RS03560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DK875_RS03565	COG0363	glucosamine-6-phosphate deaminase activity
DK875_RS03585	COG0463	Glycosyl transferase, family 2
DK875_RS03630	COG1696	Membrane protein involved in D-alanine export
DK875_RS03635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK875_RS03640	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DK875_RS03650	COG0435	Glutathione S-transferase
DK875_RS03655	COG1187	pseudouridine synthase activity
DK875_RS03660	COG0386	Belongs to the glutathione peroxidase family
DK875_RS03665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK875_RS03670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK875_RS03675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DK875_RS03680	COG1120	ATPase activity
DK875_RS03685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DK875_RS03690	COG0204	Acyl-transferase
DK875_RS03695	COG1596	polysaccharide export
DK875_RS03695	COG1555	photosystem II stabilization
DK875_RS03700	COG0658	competence protein
DK875_RS03700	COG2333	competence protein COMEC
DK875_RS03705	COG0517	IMP dehydrogenase activity
DK875_RS03720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK875_RS03725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DK875_RS03730	COG0470	DNA polymerase III
DK875_RS03735	COG4467	Involved in initiation control of chromosome replication
DK875_RS03745	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DK875_RS03755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DK875_RS03760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DK875_RS03765	COG1393	Belongs to the ArsC family
DK875_RS03775	COG0708	Exodeoxyribonuclease III
DK875_RS03785	COG0531	amino acid
DK875_RS03815	COG1061	Type III restriction enzyme res subunit
DK875_RS03840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DK875_RS03845	COG4684	Psort location CytoplasmicMembrane, score
DK875_RS03850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DK875_RS03860	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DK875_RS03900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DK875_RS03905	COG1349	DNA-binding transcription factor activity
DK875_RS03915	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK875_RS03920	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK875_RS03925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK875_RS03930	COG1882	Formate acetyltransferase
DK875_RS03950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DK875_RS03955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DK875_RS03970	COG1164	Oligoendopeptidase f
DK875_RS03985	COG0210	DNA helicase
DK875_RS04025	COG1131	(ABC) transporter
DK875_RS04065	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DK875_RS04070	COG1074	ATP-dependent DNA helicase activity
DK875_RS04080	COG0187	DNA topoisomerase II activity
DK875_RS04085	COG2184	nucleotidyltransferase activity
DK875_RS04100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DK875_RS04110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DK875_RS04130	COG0539	negative regulation of cytoplasmic translation
DK875_RS04155	COG1104	cysteine desulfurase activity
DK875_RS04160	COG0301	tRNA thio-modification
DK875_RS04165	COG1114	Component of the transport system for branched-chain amino acids
DK875_RS04170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DK875_RS04175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DK875_RS04200	COG0564	pseudouridine synthase activity
DK875_RS04205	COG2824	Alkylphosphonate utilization operon protein PhnA
DK875_RS04215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DK875_RS04220	COG0540	Belongs to the ATCase OTCase family
DK875_RS04225	COG0505	Belongs to the CarA family
DK875_RS04235	COG2521	methyltransferase
DK875_RS04235	COG2136	Putative SAM-dependent methyltransferase
DK875_RS04240	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DK875_RS04250	COG0228	four-way junction DNA binding
DK875_RS04265	COG1132	(ABC) transporter
DK875_RS04270	COG0726	polysaccharide deacetylase
DK875_RS04280	COG0083	homoserine kinase activity
DK875_RS04290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DK875_RS04295	COG3842	ATPase activity
DK875_RS04300	COG1176	ABC-type spermidine putrescine transport system, permease component I
DK875_RS04305	COG1177	transmembrane transport
DK875_RS04315	COG0038	chloride channel
DK875_RS04330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DK875_RS04335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DK875_RS04345	COG0534	Mate efflux family protein
DK875_RS04350	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DK875_RS04355	COG0336	Belongs to the RNA methyltransferase TrmD family
DK875_RS04360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DK875_RS04365	COG1349	DNA-binding transcription factor activity
DK875_RS04370	COG1105	Belongs to the carbohydrate kinase PfkB family
DK875_RS04375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK875_RS04375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK875_RS04375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK875_RS04385	COG1307	EDD domain protein, DegV family
DK875_RS04390	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DK875_RS04395	COG0617	tRNA 3'-terminal CCA addition
DK875_RS04400	COG0488	(ABC) transporter
DK875_RS04410	COG1940	carbohydrate kinase activity
DK875_RS04425	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DK875_RS04430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DK875_RS04435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DK875_RS04450	COG0481	GTPase activity
DK875_RS04480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DK875_RS04485	COG2890	protein-(glutamine-N5) methyltransferase activity
DK875_RS04490	COG0009	L-threonylcarbamoyladenylate synthase
DK875_RS04500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DK875_RS04510	COG0741	lytic transglycosylase activity
DK875_RS04515	COG4221	oxidoreductase activity
DK875_RS04540	COG1401	restriction endodeoxyribonuclease activity
DK875_RS04545	COG4268	DNA restriction-modification system
DK875_RS04555	COG2188	Transcriptional regulator
DK875_RS04560	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DK875_RS04565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DK875_RS04580	COG1660	Displays ATPase and GTPase activities
DK875_RS04585	COG4974	Belongs to the 'phage' integrase family
DK875_RS04600	COG0745	RESPONSE REGULATOR receiver
DK875_RS04620	COG1136	(ABC) transporter
DK875_RS04655	COG2382	esterase
DK875_RS04665	COG3708	Transcriptional regulator
DK875_RS04665	COG2207	Transcriptional regulator
DK875_RS04670	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DK875_RS04675	COG0647	UMP catabolic process
DK875_RS04680	COG4974	Belongs to the 'phage' integrase family
DK875_RS04690	COG1396	sequence-specific DNA binding
DK875_RS04725	COG0745	RESPONSE REGULATOR receiver
DK875_RS04730	COG2205	protein histidine kinase activity
DK875_RS04735	COG3843	relaxase mobilization nuclease domain protein
DK875_RS04750	COG0613	PHP domain protein
DK875_RS04755	COG0542	response to heat
DK875_RS04760	COG1396	sequence-specific DNA binding
DK875_RS04795	COG4443	Transcriptional Coactivator p15 (PC4)
DK875_RS04800	COG1475	DNA binding
DK875_RS04970	COG0222	ribosome binding
DK875_RS04975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DK875_RS04980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DK875_RS04985	COG0758	DNA mediated transformation
DK875_RS04990	COG0110	maltose O-acetyltransferase activity
DK875_RS04995	COG1937	Protein conserved in bacteria
DK875_RS05005	COG0446	pyridine nucleotide-disulphide oxidoreductase
DK875_RS05015	COG1272	protein, Hemolysin III
DK875_RS05025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DK875_RS05030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK875_RS05040	COG0424	maF-like protein
DK875_RS05045	COG0737	Belongs to the 5'-nucleotidase family
DK875_RS05055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DK875_RS05060	COG0463	Glycosyl transferase, family 2
DK875_RS05070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DK875_RS05075	COG0284	orotidine-5'-phosphate decarboxylase activity
DK875_RS05080	COG0167	dihydroorotate dehydrogenase activity
DK875_RS05095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DK875_RS05105	COG0297	glycogen (starch) synthase activity
DK875_RS05115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK875_RS05130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK875_RS05145	COG3583	domain protein
DK875_RS05165	COG1126	abc transporter atp-binding protein
DK875_RS05175	COG0488	(ABC) transporter
DK875_RS05265	COG3716	PTS system mannose fructose sorbose family IID component
DK875_RS05275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK875_RS05295	COG1070	Carbohydrate kinase
DK875_RS05350	COG3711	transcriptional antiterminator
DK875_RS05355	COG3684	Belongs to the aldolase LacD family
DK875_RS05360	COG1105	Belongs to the carbohydrate kinase PfkB family
DK875_RS05365	COG0698	ribose 5-phosphate isomerase
DK875_RS05370	COG0698	ribose 5-phosphate isomerase
DK875_RS05375	COG1349	DNA-binding transcription factor activity
DK875_RS05400	COG1396	sequence-specific DNA binding
DK875_RS05405	COG1194	a g-specific adenine glycosylase
DK875_RS05415	COG1132	(ABC) transporter
DK875_RS05420	COG1132	(ABC) transporter
DK875_RS05425	COG0280	phosphate acetyltransferase
DK875_RS05430	COG0564	pseudouridine synthase activity
DK875_RS05435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DK875_RS05440	COG2357	RelA SpoT domain protein
DK875_RS05445	COG4116	CYTH
DK875_RS05455	COG1104	cysteine desulfurase activity
DK875_RS05470	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DK875_RS05475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK875_RS05485	COG3764	Sortase (surface protein transpeptidase)
DK875_RS05490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DK875_RS05495	COG0039	L-malate dehydrogenase activity
DK875_RS05500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DK875_RS05510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DK875_RS05530	COG1744	ABC transporter substrate-binding protein PnrA-like
DK875_RS05545	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DK875_RS05550	COG2813	Specifically methylates the guanine in position
DK875_RS05555	COG1072	(Pantothenic acid kinase))
DK875_RS05560	COG0268	Binds directly to 16S ribosomal RNA
DK875_RS05570	COG5002	protein histidine kinase activity
DK875_RS05575	COG0745	RESPONSE REGULATOR receiver
DK875_RS05590	COG0704	Plays a role in the regulation of phosphate uptake
DK875_RS05595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK875_RS05600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK875_RS05605	COG0581	inorganic phosphate transmembrane transporter activity
DK875_RS05610	COG0573	inorganic phosphate transmembrane transporter activity
DK875_RS05620	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DK875_RS05620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK875_RS05625	COG0483	inositol monophosphate 1-phosphatase activity
DK875_RS05630	COG4476	Belongs to the UPF0223 family
DK875_RS05635	COG1393	Belongs to the ArsC family
DK875_RS05640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DK875_RS05645	COG0196	riboflavin kinase activity
DK875_RS05650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DK875_RS05690	COG0561	phosphatase activity
DK875_RS05695	COG2195	Cleaves the N-terminal amino acid of tripeptides
DK875_RS05715	COG1695	Transcriptional regulator
DK875_RS05735	COG3759	membrane
DK875_RS05740	COG1846	Transcriptional regulator
DK875_RS05755	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DK875_RS05760	COG2610	gluconate transmembrane transporter activity
DK875_RS05780	COG0302	gtp cyclohydrolase
DK875_RS05785	COG1051	belongs to the nudix hydrolase family
DK875_RS05810	COG0072	phenylalanine-tRNA ligase activity
DK875_RS05810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK875_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
DK875_RS05845	COG1312	Catalyzes the dehydration of D-mannonate
DK875_RS05855	COG0800	Aldolase
DK875_RS05865	COG3250	beta-galactosidase activity
DK875_RS05890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK875_RS05900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DK875_RS05905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DK875_RS05910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DK875_RS05915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DK875_RS05920	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DK875_RS05925	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DK875_RS05930	COG0356	it plays a direct role in the translocation of protons across the membrane
DK875_RS05940	COG1597	lipid kinase activity
DK875_RS05955	COG0701	Predicted permease
DK875_RS05960	COG3689	TIGRFAM TIGR03943 family protein
DK875_RS05965	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DK875_RS05980	COG0552	protein localization to endoplasmic reticulum
DK875_RS05985	COG0561	phosphatase activity
DK875_RS05990	COG0561	phosphatase activity
DK875_RS05995	COG1196	nuclear chromosome segregation
DK875_RS06030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK875_RS06035	COG0538	isocitrate dehydrogenase activity
DK875_RS06040	COG0372	Belongs to the citrate synthase family
DK875_RS06045	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DK875_RS06050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DK875_RS06055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DK875_RS06060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DK875_RS06065	COG1609	Transcriptional regulator
DK875_RS06085	COG5492	domain, Protein
DK875_RS06100	COG3716	PTS system mannose fructose sorbose family IID component
DK875_RS06110	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK875_RS06115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DK875_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
DK875_RS06175	COG1476	TRANSCRIPTIONal
DK875_RS06195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DK875_RS06205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DK875_RS06210	COG4122	O-methyltransferase activity
DK875_RS06235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK875_RS06235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK875_RS06245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DK875_RS06250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DK875_RS06255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DK875_RS06260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DK875_RS06265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DK875_RS06265	COG1116	anion transmembrane transporter activity
DK875_RS06270	COG4120	Belongs to the binding-protein-dependent transport system permease family
DK875_RS06285	COG3684	Belongs to the aldolase LacD family
DK875_RS06295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK875_RS06300	COG1126	abc transporter atp-binding protein
DK875_RS06305	COG0765	amino acid transport
DK875_RS06310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DK875_RS06345	COG1192	Involved in chromosome partitioning
DK875_RS06445	COG3942	CHAP domain
DK875_RS06445	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK875_RS06505	COG2755	lipolytic protein G-D-S-L family
DK875_RS06505	COG0657	acetylesterase activity
DK875_RS06510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK875_RS06525	COG0469	pyruvate kinase activity
DK875_RS06530	COG0205	6-phosphofructokinase activity
DK875_RS06540	COG2188	Transcriptional regulator
DK875_RS06545	COG1131	(ABC) transporter
DK875_RS06555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DK875_RS06590	COG2151	metal-sulfur cluster biosynthetic enzyme
DK875_RS06595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DK875_RS06600	COG0358	DNA primase activity
DK875_RS06605	COG1970	mechanosensitive ion channel activity
DK875_RS06610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DK875_RS06615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DK875_RS06625	COG0647	UMP catabolic process
DK875_RS06630	COG1051	belongs to the nudix hydrolase family
DK875_RS06640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DK875_RS06650	COG0058	SHG alpha-glucan phosphorylase activity
DK875_RS06655	COG0813	purine-nucleoside phosphorylase activity
DK875_RS06660	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DK875_RS06670	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DK875_RS06675	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DK875_RS06695	COG1518	maintenance of DNA repeat elements
DK875_RS06705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DK875_RS06720	COG2268	Band 7 protein
DK875_RS06725	COG1704	LemA family
DK875_RS06735	COG1573	uracil-dna glycosylase
DK875_RS06755	COG2226	methyltransferase
DK875_RS06760	COG0488	(ABC) transporter
DK875_RS06765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DK875_RS06780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK875_RS06785	COG3442	glutamine amidotransferase
DK875_RS06790	COG2226	methyltransferase
DK875_RS06800	COG0488	(ABC) transporter
DK875_RS06845	COG3842	ATPase activity
DK875_RS06865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK875_RS06865	COG2190	(PTS) system
DK875_RS06865	COG1263	PTS System
DK875_RS06870	COG3711	transcriptional antiterminator
DK875_RS06875	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DK875_RS06880	COG3527	Alpha-acetolactate decarboxylase
DK875_RS06890	COG0628	permease
DK875_RS06895	COG2706	6-phosphogluconolactonase activity
DK875_RS06905	COG1011	Hydrolase
DK875_RS06935	COG0560	Phosphoserine phosphatase
DK875_RS06940	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DK875_RS06945	COG0187	DNA topoisomerase II activity
DK875_RS06950	COG0693	protein deglycase activity
DK875_RS06955	COG0772	Belongs to the SEDS family
DK875_RS06975	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DK875_RS06980	COG0716	FMN binding
DK875_RS06990	COG0287	Prephenate dehydrogenase
DK875_RS06990	COG1605	Chorismate mutase
DK875_RS06995	COG0038	chloride channel
DK875_RS07255	COG3561	AntA/AntB antirepressor
DK875_RS07310	COG0737	Belongs to the 5'-nucleotidase family
DK875_RS07315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DK875_RS07320	COG1466	dna polymerase III delta subunit
DK875_RS07355	COG0683	leucine binding
DK875_RS07370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DK875_RS07375	COG0366	Alpha amylase catalytic
DK875_RS07385	COG0395	ABC-type sugar transport system, permease component
DK875_RS07390	COG1175	transmembrane transport
DK875_RS07395	COG1653	transport
DK875_RS07405	COG2207	Transcriptional regulator
DK875_RS07410	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DK875_RS07415	COG0626	cystathionine gamma-synthase activity
DK875_RS07435	COG3547	Transposase (IS116 IS110 IS902 family)
DK875_RS07440	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DK875_RS07445	COG2827	Endonuclease containing a URI domain
DK875_RS07470	COG0640	Transcriptional regulator
DK875_RS07475	COG0513	Belongs to the DEAD box helicase family
DK875_RS07480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK875_RS07530	COG2177	Part of the ABC transporter FtsEX involved in
DK875_RS07535	COG2884	Cell division ATP-binding protein ftsE
DK875_RS07545	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DK875_RS07590	COG1078	dGTPase activity
DK875_RS07605	COG0149	triose-phosphate isomerase activity
DK875_RS07610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DK875_RS07625	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DK875_RS07630	COG0772	Belongs to the SEDS family
DK875_RS07650	COG3859	Proton-coupled thiamine transporter YuaJ
DK875_RS07660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DK875_RS07670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DK875_RS07695	COG0577	efflux transmembrane transporter activity
DK875_RS07700	COG1136	(ABC) transporter
DK875_RS07705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK875_RS07715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK875_RS07725	COG1268	BioY protein
DK875_RS07730	COG4443	Transcriptional Coactivator p15 (PC4)
DK875_RS07755	COG0789	Transcriptional regulator
DK875_RS07790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DK875_RS07800	COG0765	amino acid transport
DK875_RS07805	COG4703	Protein of unknown function (DUF1797)
DK875_RS07810	COG0542	response to heat
DK875_RS07840	COG3599	regulation of cell shape
DK875_RS07855	COG1799	cell septum assembly
DK875_RS07860	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DK875_RS07865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DK875_RS07880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DK875_RS07915	COG1227	inorganic diphosphatase activity
DK875_RS07925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DK875_RS07930	COG1253	flavin adenine dinucleotide binding
DK875_RS07935	COG1119	ATPase activity
DK875_RS07940	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DK875_RS07950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DK875_RS07955	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DK875_RS07970	COG4470	Protein conserved in bacteria
DK875_RS07975	COG3480	Lon protease (S16) C-terminal proteolytic domain
DK875_RS07980	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DK875_RS07985	COG0742	ribosomal rna small subunit methyltransferase
DK875_RS07995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DK875_RS08000	COG4483	Protein conserved in bacteria
DK875_RS08005	COG2197	response regulator
DK875_RS08010	COG4585	Histidine kinase
DK875_RS08010	COG2203	Gaf domain
DK875_RS08015	COG0842	Transport permease protein
DK875_RS08020	COG1131	(ABC) transporter
DK875_RS08040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DK875_RS08050	COG2755	lipolytic protein G-D-S-L family
DK875_RS08050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DK875_RS08055	COG0671	phosphoesterase, PA-phosphatase related
DK875_RS08060	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DK875_RS08075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DK875_RS08080	COG1187	pseudouridine synthase activity
DK875_RS08085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DK875_RS08090	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DK875_RS08095	COG0582	viral genome integration into host DNA
DK875_RS08115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DK875_RS08120	COG3763	UPF0154 protein
DK875_RS08130	COG3579	cysteine-type endopeptidase activity
DK875_RS08145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK875_RS08150	COG1254	Belongs to the acylphosphatase family
DK875_RS08160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DK875_RS08165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DK875_RS08180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DK875_RS08190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DK875_RS08200	COG1160	GTP binding
DK875_RS08210	COG1484	DNA-dependent DNA replication
DK875_RS08220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DK875_RS08225	COG0628	permease
DK875_RS08230	COG0745	RESPONSE REGULATOR receiver
DK875_RS08235	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DK875_RS08245	COG0492	ferredoxin-NADP+ reductase activity
DK875_RS08255	COG0513	Belongs to the DEAD box helicase family
DK875_RS08295	COG0494	nUDIX hydrolase
DK875_RS08300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DK875_RS08310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DK875_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
DK875_RS08340	COG0577	efflux transmembrane transporter activity
DK875_RS08345	COG1136	(ABC) transporter
DK875_RS08350	COG2205	protein histidine kinase activity
DK875_RS08365	COG0436	Aminotransferase
DK875_RS08375	COG1174	glycine betaine transport
DK875_RS08380	COG1125	glycine betaine transport
DK875_RS08380	COG0517	IMP dehydrogenase activity
DK875_RS08400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DK875_RS08405	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DK875_RS08410	COG1482	cell wall glycoprotein biosynthetic process
DK875_RS08425	COG3091	SprT-like family
DK875_RS08430	COG2183	response to ionizing radiation
DK875_RS08450	COG0656	L-ascorbic acid biosynthetic process
DK875_RS08455	COG4708	membrane
DK875_RS08460	COG2246	polysaccharide biosynthetic process
DK875_RS08470	COG0024	Methionine aminopeptidase
DK875_RS08480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK875_RS08490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DK875_RS08495	COG2131	deaminase
DK875_RS08505	COG1363	Peptidase, m42
DK875_RS08525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DK875_RS08530	COG1956	GAF domain-containing protein
DK875_RS08550	COG0673	inositol 2-dehydrogenase activity
DK875_RS08555	COG0513	Belongs to the DEAD box helicase family
DK875_RS08560	COG0726	polysaccharide deacetylase
DK875_RS08575	COG0183	Belongs to the thiolase family
DK875_RS08580	COG3425	synthase
DK875_RS08610	COG0776	regulation of translation
DK875_RS08620	COG2755	lipolytic protein G-D-S-L family
DK875_RS08625	COG1307	EDD domain protein, DegV family
DK875_RS08630	COG0497	DNA recombination
DK875_RS08635	COG1438	arginine binding
DK875_RS08640	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DK875_RS08650	COG1722	exodeoxyribonuclease VII activity
DK875_RS08655	COG1570	exodeoxyribonuclease VII activity
DK875_RS08660	COG2321	neutral zinc metallopeptidase
DK875_RS08670	COG1755	Isoprenylcysteine carboxyl methyltransferase
DK875_RS08675	COG5002	protein histidine kinase activity
DK875_RS08680	COG0745	RESPONSE REGULATOR receiver
DK875_RS08755	COG1083	cytidylyl-transferase
DK875_RS08755	COG2755	lipolytic protein G-D-S-L family
DK875_RS08770	COG2089	acid synthase
DK875_RS08800	COG1442	glycosyl transferase family 8
DK875_RS08800	COG1216	Glycosyl transferase, family 2
DK875_RS08805	COG1216	Glycosyl transferase, family 2
DK875_RS08805	COG1442	glycosyl transferase family 8
DK875_RS08820	COG0438	transferase activity, transferring glycosyl groups
DK875_RS08835	COG4464	protein tyrosine phosphatase activity
DK875_RS08845	COG3944	biosynthesis protein
DK875_RS08850	COG1316	TRANSCRIPTIONal
DK875_RS08855	COG3022	response to hydroperoxide
DK875_RS08860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK875_RS08875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DK875_RS08880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DK875_RS08885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DK875_RS08910	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DK875_RS08915	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DK875_RS08920	COG1609	Transcriptional regulator
DK875_RS08930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DK875_RS08935	COG0154	amidase activity
DK875_RS08940	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DK875_RS08950	COG0335	large ribosomal subunit rRNA binding
DK875_RS08960	COG1335	isochorismatase
DK875_RS08965	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DK875_RS08970	COG0436	Aminotransferase
DK875_RS09000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DK875_RS09035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DK875_RS09040	COG0191	fructose-bisphosphate aldolase activity
DK875_RS09050	COG0504	CTP synthase activity
DK875_RS09055	COG3343	RNA polymerase activity
DK875_RS09090	COG0544	peptidyl-prolyl cis-trans isomerase activity
DK875_RS09110	COG1902	pentaerythritol trinitrate reductase activity
DK875_RS09110	COG0446	pyridine nucleotide-disulphide oxidoreductase
DK875_RS09115	COG4221	oxidoreductase activity
DK875_RS09140	COG4475	Protein of unknown function (DUF436)
DK875_RS09165	COG2217	Heavy metal translocating P-type atpase
DK875_RS09175	COG3655	Transcriptional regulator
DK875_RS09190	COG0765	amino acid transport
DK875_RS09195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK875_RS09205	COG0095	Lipoate-protein ligase
DK875_RS09210	COG0484	heat shock protein binding
DK875_RS09215	COG0443	Heat shock 70 kDa protein
DK875_RS09220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DK875_RS09225	COG1420	regulation of RNA biosynthetic process
DK875_RS09230	COG0588	phosphoglycerate mutase activity
DK875_RS09235	COG2848	UPF0210 protein
DK875_RS09240	COG3830	Belongs to the UPF0237 family
DK875_RS09245	COG1132	(ABC) transporter
DK875_RS09250	COG1132	(ABC) transporter
DK875_RS09255	COG1304	FMN binding
DK875_RS09270	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DK875_RS09275	COG0534	Mate efflux family protein
DK875_RS09280	COG1129	ABC transporter
DK875_RS09295	COG1132	(ABC) transporter
DK875_RS09315	COG1012	belongs to the aldehyde dehydrogenase family
DK875_RS09315	COG1454	alcohol dehydrogenase
DK875_RS09320	COG1064	alcohol dehydrogenase
DK875_RS09325	COG0124	histidyl-tRNA synthetase
DK875_RS09335	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DK875_RS09340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK875_RS09355	COG0494	nUDIX hydrolase
DK875_RS09360	COG0433	COG0433 Predicted ATPase
DK875_RS09365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DK875_RS09375	COG1346	cytolysis
DK875_RS09380	COG1380	Effector of murein hydrolase LrgA
DK875_RS09400	COG1511	domain protein
DK875_RS09405	COG1309	transcriptional regulator
DK875_RS09410	COG1131	(ABC) transporter
DK875_RS09425	COG0561	phosphatase activity
DK875_RS09430	COG2843	Capsule synthesis protein
DK875_RS09435	COG0167	dihydroorotate dehydrogenase activity
DK875_RS09440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DK875_RS09450	COG0668	transmembrane transport
DK875_RS09460	COG1115	amino acid carrier protein
DK875_RS09520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DK875_RS09520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DK875_RS09530	COG3118	belongs to the thioredoxin family
DK875_RS09585	COG1193	negative regulation of DNA recombination
DK875_RS09600	COG2188	Transcriptional regulator
DK875_RS09605	COG1263	PTS System
DK875_RS09605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK875_RS09610	COG0366	Alpha amylase catalytic
DK875_RS09630	COG0681	Belongs to the peptidase S26 family
DK875_RS09635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DK875_RS09640	COG2217	Heavy metal translocating P-type atpase
DK875_RS09650	COG2217	Heavy metal translocating P-type atpase
DK875_RS09655	COG0363	glucosamine-6-phosphate deaminase activity
DK875_RS09690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK875_RS09710	COG2910	NAD(P)H-binding
DK875_RS09725	COG1882	Formate acetyltransferase
DK875_RS09730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DK875_RS09750	COG2222	sugar isomerase
DK875_RS09755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DK875_RS09760	COG0584	glycerophosphoryl diester phosphodiesterase
DK875_RS09765	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DK875_RS09770	COG3959	Transketolase, thiamine diphosphate binding domain
DK875_RS09795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK875_RS09805	COG2723	6-phospho-beta-galactosidase activity
DK875_RS09810	COG2081	HI0933 family
DK875_RS09820	COG1131	(ABC) transporter
DK875_RS09830	COG2855	membrane
DK875_RS09850	COG0395	ABC-type sugar transport system, permease component
DK875_RS09855	COG1175	transmembrane transport
DK875_RS09865	COG2207	Transcriptional regulator
DK875_RS09870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DK875_RS09880	COG1214	PFAM Peptidase M22, glycoprotease
DK875_RS09895	COG0174	glutamine synthetase
DK875_RS09900	COG0789	Transcriptional regulator
DK875_RS09910	COG0126	phosphoglycerate kinase activity
DK875_RS09920	COG3590	peptidase
DK875_RS09925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DK875_RS09930	COG0049	tRNA binding
DK875_RS09940	COG0459	protein refolding
DK875_RS09965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK875_RS09975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DK875_RS09985	COG1363	Peptidase, m42
DK875_RS09990	COG0285	dihydrofolate synthase activity
DK875_RS10000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DK875_RS10030	COG4537	Required for transformation and DNA binding
DK875_RS10035	COG1459	type II secretion system
DK875_RS10040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DK875_RS10045	COG1619	proteins homologs of microcin C7 resistance protein MccF
DK875_RS10055	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DK875_RS10060	COG0085	RNA polymerase activity
DK875_RS10065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK875_RS10090	COG0803	Belongs to the bacterial solute-binding protein 9 family
DK875_RS10090	COG3443	Belongs to the bacterial solute-binding protein 9 family
DK875_RS10095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK875_RS10100	COG1121	(ABC) transporter
DK875_RS10205	COG1739	Uncharacterized protein family UPF0029
DK875_RS10210	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DK875_RS10235	COG0515	serine threonine protein kinase
DK875_RS10235	COG2815	serine threonine protein kinase
DK875_RS10240	COG0631	protein serine/threonine phosphatase activity
DK875_RS10245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK875_RS10245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK875_RS10250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DK875_RS10255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DK875_RS10260	COG1758	RNA polymerase activity
DK875_RS10270	COG1418	mRNA catabolic process
DK875_RS10275	COG1854	S-ribosylhomocysteine lyase activity
DK875_RS10285	COG0116	Belongs to the methyltransferase superfamily
DK875_RS10295	COG3599	regulation of cell shape
DK875_RS10300	COG4474	Belongs to the UPF0398 family
DK875_RS10305	COG3331	DNA recombination
DK875_RS10310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK875_RS10315	COG0357	Ribosomal RNA small subunit methyltransferase G
DK875_RS10330	COG1122	ATPase activity
DK875_RS10350	COG4720	Psort location CytoplasmicMembrane, score
DK875_RS10360	COG0217	transcriptional regulatory protein
DK875_RS10375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK875_RS10375	COG1263	PTS System
DK875_RS10375	COG2190	(PTS) system
DK875_RS10390	COG0058	SHG alpha-glucan phosphorylase activity
DK875_RS10395	COG1640	4-alpha-glucanotransferase
DK875_RS10405	COG0242	peptide deformylase activity
DK875_RS10430	COG0285	dihydrofolate synthase activity
DK875_RS10635	COG0556	nucleotide-excision repair
DK875_RS10705	COG4974	Belongs to the 'phage' integrase family
DK875_RS10725	COG4974	Belongs to the 'phage' integrase family
DK875_RS10735	COG1098	S1 RNA binding domain
DK875_RS10775	COG1438	arginine binding
DK875_RS10780	COG0018	arginyl-trna synthetase
DK875_RS10800	COG1640	4-alpha-glucanotransferase
DK875_RS10805	COG2182	Extracellular solute-binding protein
DK875_RS10810	COG1175	transmembrane transport
DK875_RS10815	COG3833	ABC-type maltose transport systems, permease component
DK875_RS10820	COG5521	maltodextrose utilization protein MalA
DK875_RS10825	COG1609	Transcriptional regulator
DK875_RS10830	COG1523	belongs to the glycosyl hydrolase 13 family
DK875_RS10835	COG1780	Probably involved in ribonucleotide reductase function
DK875_RS10840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK875_RS10845	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DK875_RS10850	COG2153	protein acetylation
DK875_RS10855	COG4989	oxidoreductase activity
DK875_RS10860	COG1216	Glycosyl transferase, family 2
DK875_RS10880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DK875_RS10890	COG0305	Participates in initiation and elongation during chromosome replication
DK875_RS10895	COG0359	binds to the 23S rRNA
DK875_RS10905	COG0445	tRNA wobble uridine modification
DK875_RS10910	COG0494	nUDIX hydrolase
DK875_RS10915	COG1733	regulation of RNA biosynthetic process
DK875_RS10925	COG0482	sulfurtransferase activity
DK875_RS10930	COG1760	l-serine dehydratase
DK875_RS10935	COG1760	l-serine dehydratase
DK875_RS10945	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DK875_RS10950	COG1122	ATPase activity
DK875_RS10955	COG1122	ATPase activity
DK875_RS10960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DK875_RS10965	COG1426	Protein conserved in bacteria
DK875_RS10970	COG0612	Peptidase, M16
DK875_RS10975	COG0612	Peptidase, M16
DK875_RS11065	COG0582	viral genome integration into host DNA
DK875_RS11075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DK875_RS11085	COG0516	GMP reductase activity
DK875_RS11085	COG0517	IMP dehydrogenase activity
DK875_RS11095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK875_RS11100	COG0488	(ABC) transporter
DK875_RS11130	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DK875_RS11135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DK875_RS11140	COG1475	DNA binding