locus-tag	class	description
DK878_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
DK878_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DK878_RS00030	ENOG4105C3G	gtp-binding protein
DK878_RS00035	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
DK878_RS00040	ENOG4108JA2	transcriptioN-repair coupling factor
DK878_RS00045	ENOG41082I2	s4 domain protein
DK878_RS00060	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DK878_RS00070	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DK878_RS00180	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
DK878_RS00195	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DK878_RS00200	ENOG4105CHM	Aminotransferase
DK878_RS00205	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
DK878_RS00210	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
DK878_RS00215	ENOG41086VD	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DK878_RS00225	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
DK878_RS00230	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
DK878_RS00235	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
DK878_RS00240	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
DK878_RS00245	ENOG4105DC1	bifunctional purine biosynthesis protein purh
DK878_RS00270	ENOG4105C12	Phosphoribosylglycinamide synthetase
DK878_RS00275	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
DK878_RS00290	ENOG4105C83	adenylosuccinate lyase
DK878_RS00330	ENOG4105BZ1	(ABC) transporter
DK878_RS00340	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DK878_RS00350	ENOG4107XGZ	Hydrolase
DK878_RS00360	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DK878_RS00370	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
DK878_RS00375	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
DK878_RS00380	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DK878_RS00390	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
DK878_RS00395	ENOG410888K	transcriptional regulator, Spx
DK878_RS00400	ENOG4105VBH	UPF0297 protein
DK878_RS00405	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
DK878_RS00410	ENOG4105VPH	UPF0473 protein
DK878_RS00425	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DK878_RS00430	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DK878_RS00435	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DK878_RS00440	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DK878_RS00445	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DK878_RS00450	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DK878_RS00455	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DK878_RS00460	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
DK878_RS00465	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
DK878_RS00470	ENOG41082SA	50s ribosomal protein l29
DK878_RS00475	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DK878_RS00480	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
DK878_RS00485	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
DK878_RS00490	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DK878_RS00495	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
DK878_RS00500	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DK878_RS00505	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DK878_RS00510	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
DK878_RS00515	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DK878_RS00520	ENOG4105VPB	50S ribosomal protein L30
DK878_RS00530	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
DK878_RS00535	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DK878_RS00540	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
DK878_RS00550	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DK878_RS00560	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DK878_RS00675	ENOG4105FDK	ABC transporter
DK878_RS00685	ENOG4105DSE	periplasmic solute binding protein
DK878_RS00690	ENOG4105NA0	Transcriptional regulator
DK878_RS00710	ENOG4105BZ4	penicillin-binding protein
DK878_RS00715	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DK878_RS00720	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DK878_RS00775	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
DK878_RS00785	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DK878_RS00790	ENOG4105CN9	Peptidase m42 family protein
DK878_RS00810	ENOG4108VDD	TRNA binding domain protein
DK878_RS00835	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DK878_RS00845	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DK878_RS00850	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DK878_RS00855	ENOG4105C9K	Endothelin-converting enzyme 1
DK878_RS00860	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DK878_RS00865	ENOG4105BZA	Phosphoglycerate kinase
DK878_RS00875	ENOG4105KV4	Transcriptional regulator
DK878_RS00880	ENOG4105C5F	glutamine synthetase
DK878_RS00895	ENOG41072GX	Peptidase M22 Glycoprotease
DK878_RS00905	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DK878_RS00925	ENOG4105DRS	transport system, permease
DK878_RS00945	ENOG4105HMI	Membrane
DK878_RS00955	ENOG4105DA5	(ABC) transporter
DK878_RS00965	ENOG4105CBX	hi0933 family
DK878_RS00970	ENOG4105CS2	ec 3.2.1.21
DK878_RS00980	ENOG4108XBJ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
DK878_RS00995	ENOG4108HHA	Transketolase
DK878_RS01000	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DK878_RS01005	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
DK878_RS01015	ENOG4105E70	isomerase
DK878_RS01035	ENOG4107S1E	Beta-lactamase
DK878_RS01045	ENOG41068JE	domain protein
DK878_RS01050	ENOG4105C6N	Formate acetyltransferase
DK878_RS01065	ENOG4108RYK	Nad-dependent epimerase dehydratase
DK878_RS01085	ENOG4105CK1	PTS System
DK878_RS01120	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
DK878_RS01125	ENOG4105C59	p-type ATPase
DK878_RS01135	ENOG4105C59	p-type ATPase
DK878_RS01140	ENOG4105C7H	Helicase, RecD TraA family
DK878_RS01145	ENOG4105C3F	Signal peptidase i
DK878_RS01165	ENOG4105CG3	alpha amylase, catalytic region
DK878_RS01170	ENOG4105C5Y	PTS System
DK878_RS01175	ENOG4107414	GntR family transcriptional regulator
DK878_RS01190	ENOG4105C98	muts2 protein
DK878_RS01255	ENOG4105K63	Thioredoxin
DK878_RS01265	ENOG4105E0X	reductase
DK878_RS01315	ENOG4105BZG	amino acid carrier protein
DK878_RS01320	ENOG4105D8X	mechanosensitive ion channel
DK878_RS01330	ENOG4107R37	Glutamate dehydrogenase
DK878_RS01335	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
DK878_RS01340	ENOG4105PNM	synthesis protein
DK878_RS01345	ENOG4108HCJ	Hydrolase
DK878_RS01360	ENOG4105CJ1	ABC, transporter
DK878_RS01365	ENOG4105ST3	Transcriptional regulator
DK878_RS01405	ENOG41067MG	lrgb family
DK878_RS01410	ENOG4107V9H	nitrite transporter
DK878_RS01415	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DK878_RS01420	ENOG4105D7A	ATP-binding protein
DK878_RS01425	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
DK878_RS01450	ENOG41086FC	50S ribosomal protein l32
DK878_RS01455	ENOG4105CUT	histidyl-tRNA synthetase
DK878_RS01465	ENOG4105C0A	alcohol dehydrogenase
DK878_RS01470	ENOG4105D98	threonine synthase
DK878_RS01475	ENOG4108JJ9	ABC, transporter
DK878_RS01480	ENOG4105BZ1	(ABC) transporter
DK878_RS01495	ENOG4108JJB	ABC transporter
DK878_RS01500	ENOG4105UQX	Mate efflux family protein
DK878_RS01505	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
DK878_RS01520	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
DK878_RS01525	ENOG4105BZ1	(ABC) transporter
DK878_RS01530	ENOG4105BZ1	(ABC) transporter
DK878_RS01535	ENOG4105VUC	UPF0237 protein
DK878_RS01540	ENOG4105CAG	UPF0210 protein
DK878_RS01545	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DK878_RS01550	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
DK878_RS01555	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DK878_RS01560	ENOG4105CFG	Acts as a chaperone (By similarity)
DK878_RS01565	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DK878_RS01570	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
DK878_RS01580	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
DK878_RS01585	ENOG4105E5Q	amino acid AbC transporter
DK878_RS01600	ENOG4105VMP	Transcriptional regulator
DK878_RS01610	ENOG4105C59	p-type ATPase
DK878_RS01635	ENOG4108UIC	UPF0340 protein
DK878_RS01665	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DK878_RS01685	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
DK878_RS01715	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
DK878_RS01720	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DK878_RS01730	ENOG4105D2N	Aldolase
DK878_RS01735	ENOG4105VB9	50S ribosomal protein l28
DK878_RS01770	ENOG4105CB5	ATP-dependent DNA helicase recG
DK878_RS01780	ENOG4105HDK	L-asparaginase
DK878_RS01800	ENOG4105CHM	Aminotransferase
DK878_RS01805	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
DK878_RS01820	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
DK878_RS01830	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DK878_RS01835	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DK878_RS01840	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DK878_RS01850	ENOG4105CQ4	Transcriptional regulator
DK878_RS01855	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
DK878_RS01875	ENOG4106N3A	copper homeostasis protein cutc
DK878_RS01885	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DK878_RS01890	ENOG4105CQW	ribosome biogenesis GTPase YqeH
DK878_RS01895	ENOG410812S	Rna-binding protein
DK878_RS01900	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
DK878_RS01905	ENOG4108WF2	Metal Dependent Phosphohydrolase
DK878_RS01915	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
DK878_RS01920	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
DK878_RS01925	ENOG4105DXX	methyltransferase
DK878_RS01940	ENOG4107TXC	Transcriptional regulator
DK878_RS01950	ENOG4107YDN	peptide deformylase
DK878_RS01960	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
DK878_RS01965	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
DK878_RS01980	ENOG4105CI1	PTS System
DK878_RS01995	ENOG4105CDY	transcriptional regulatory protein
DK878_RS02005	ENOG4108V7D	UPF0397 protein
DK878_RS02015	ENOG4105C72	UPF0176 protein
DK878_RS02025	ENOG4108JJB	ABC transporter
DK878_RS02040	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
DK878_RS02045	ENOG4105BZ4	penicillin-binding protein
DK878_RS02050	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
DK878_RS02055	ENOG4108UKS	UPF0398 protein
DK878_RS02060	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
DK878_RS02070	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
DK878_RS02075	ENOG41070VT	
DK878_RS02080	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
DK878_RS02085	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
DK878_RS02095	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
DK878_RS02100	ENOG4105C25	Primosomal protein n'
DK878_RS02105	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
DK878_RS02110	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DK878_RS02115	ENOG4108ZF3	Phosphatase
DK878_RS02120	ENOG4105D9P	serine threonine protein kinase
DK878_RS02130	ENOG4105ENE	Histidine kinase
DK878_RS02145	ENOG41060GV	RNA binding s1 domain protein
DK878_RS02155	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DK878_RS02320	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
DK878_RS02325	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
DK878_RS02350	ENOG4105D1Q	UPF0246 protein
DK878_RS02360	ENOG4105HTX	biosynthesis protein
DK878_RS02370	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
DK878_RS02385	ENOG4105CPK	Glycosyl transferase (Group 1
DK878_RS02435	ENOG4105D2T	synthase
DK878_RS02450	ENOG4105F0R	Cytidylyltransferase
DK878_RS02515	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
DK878_RS02520	ENOG4105CQC	Prephenate dehydratase
DK878_RS02525	ENOG4108RCF	TRANSCRIPTIONal
DK878_RS02530	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DK878_RS02540	ENOG4105D5D	udp-galactopyranose mutase
DK878_RS02545	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
DK878_RS02560	ENOG4105CHM	Aminotransferase
DK878_RS02580	ENOG4105UQX	Mate efflux family protein
DK878_RS02585	ENOG4105KME	endoribonuclease L-psp
DK878_RS02590	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
DK878_RS02595	ENOG4105CHW	UPF0052 protein
DK878_RS02600	ENOG4105CIE	May be required for sporulation (By similarity)
DK878_RS02620	ENOG4105DBV	ornithine carbamoyltransferase
DK878_RS02625	ENOG4105C5B	carbamate kinase
DK878_RS02630	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
DK878_RS02635	ENOG4107QSE	Dipeptidase
DK878_RS02640	ENOG41069UX	Beta-N-acetyl-hexosaminidase
DK878_RS02645	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
DK878_RS02650	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
DK878_RS02655	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
DK878_RS02690	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
DK878_RS02695	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
DK878_RS02700	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
DK878_RS02710	ENOG4105CHF	Glutathione S-transferase
DK878_RS02720	ENOG4108V06	Glutathione peroxidase
DK878_RS02725	ENOG4105EHG	Permease protein
DK878_RS02730	ENOG4105DQ5	transport system permease protein
DK878_RS02740	ENOG4105E0A	ABC, transporter
DK878_RS02745	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
DK878_RS02750	ENOG4105F6E	Acyl-transferase
DK878_RS02755	ENOG4105KQC	Competence protein
DK878_RS02760	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
DK878_RS02770	ENOG41080XP	Cbs domain
DK878_RS02785	ENOG4108JYZ	YitT family
DK878_RS02790	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DK878_RS02795	ENOG4105FA2	dna polymerase iii
DK878_RS02800	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
DK878_RS02805	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
DK878_RS02810	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
DK878_RS02825	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DK878_RS02830	ENOG41080E8	Transcriptional regulator, Spx MgsR family
DK878_RS02840	ENOG4105CGK	Exodeoxyribonuclease III
DK878_RS02850	ENOG4105CUB	amino acid
DK878_RS02880	ENOG4105F6A	helicase
DK878_RS02910	ENOG4105FH5	Membrane
DK878_RS02915	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DK878_RS02920	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DK878_RS02925	ENOG4105CKU	formyltetrahydrofolate synthetase
DK878_RS02965	ENOG4105F1A	Pyruvate formate-lyase
DK878_RS02970	ENOG4105N2W	Transcriptional regulator
DK878_RS02975	ENOG4105DKT	Transcriptional regulator
DK878_RS02980	ENOG4105VCP	PTS System
DK878_RS02985	ENOG4105VZJ	PTS System
DK878_RS02990	ENOG4105CK1	PTS System
DK878_RS03015	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
DK878_RS03020	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DK878_RS03035	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
DK878_RS03125	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DK878_RS03135	ENOG4105EVI	UPF0374 protein
DK878_RS03145	ENOG4105FDP	GntR family transcriptional regulator
DK878_RS03150	ENOG4105FDP	GntR family transcriptional regulator
DK878_RS03160	ENOG4108UZY	PTS System
DK878_RS03170	ENOG4105F3R	pts system mannose fructose sorbose family iid
DK878_RS03180	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
DK878_RS03195	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
DK878_RS03230	ENOG4105M6F	mutator MutT protein
DK878_RS03245	ENOG4105CI3	gtp-binding protein typa
DK878_RS03260	ENOG4105C3F	Signal peptidase i
DK878_RS03295	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DK878_RS03310	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DK878_RS03315	ENOG4105DFA	alanine racemase domain protein
DK878_RS03320	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
DK878_RS03335	ENOG4105MMF	Cell division protein DIVIVA
DK878_RS03365	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DK878_RS03370	ENOG4107IN1	Protein of unknown function (DUF1797)
DK878_RS03375	ENOG4105E5Q	amino acid AbC transporter
DK878_RS03385	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
DK878_RS03395	ENOG4105C3F	Signal peptidase i
DK878_RS03420	ENOG4105VUF	Transcriptional regulator
DK878_RS03435	ENOG4105CFP	Peptidase U32
DK878_RS03445	ENOG4105VEM	Conserved domain protein
DK878_RS03450	ENOG4105VKD	bioY protein
DK878_RS03460	ENOG4105DC8	reductase
DK878_RS03470	ENOG4107X8C	Efflux transporter RND family MFP subunit
DK878_RS03475	ENOG4105C19	ABC transporter
DK878_RS03480	ENOG4107RBB	ABC transporter, permease
DK878_RS03500	ENOG4105CRK	lysyL-tRNA synthetase
DK878_RS03510	ENOG4108Z66	YbaK ebsC protein
DK878_RS03520	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
DK878_RS03540	ENOG4105CNI	cell division protein FtsW
DK878_RS03545	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
DK878_RS03560	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DK878_RS03565	ENOG4105CP7	Triose-phosphate isomerase
DK878_RS03575	ENOG4105DCI	Phosphohydrolase
DK878_RS03610	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
DK878_RS03620	ENOG4105CAK	Cell division ATP-binding protein ftsE
DK878_RS03625	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
DK878_RS03650	ENOG4105BZ1	(ABC) transporter
DK878_RS03655	ENOG4105BZ1	(ABC) transporter
DK878_RS03670	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
DK878_RS03680	ENOG4105QEK	Transcriptional regulator
DK878_RS03690	ENOG4107YR5	Diacylglycerol kinase
DK878_RS03695	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
DK878_RS03700	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
DK878_RS03705	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
DK878_RS03710	ENOG4105C6X	Major Facilitator
DK878_RS03715	ENOG410861F	50S ribosomal protein L33
DK878_RS03725	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
DK878_RS03730	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
DK878_RS03735	ENOG4105CPQ	Dehydrogenase
DK878_RS03745	ENOG4105DZW	Dipeptidase
DK878_RS03750	ENOG4105C59	p-type ATPase
DK878_RS03755	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
DK878_RS03775	ENOG410836F	Transposase
DK878_RS03785	ENOG4105C2M	dna polymerase I
DK878_RS03795	ENOG4105K4P	CoA-binding domain protein
DK878_RS03805	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
DK878_RS03810	ENOG4105DC7	peptidase M24
DK878_RS03815	ENOG4105ETE	Transcriptional regulator (LacI family
DK878_RS03825	ENOG4105W2C	Glycosyl transferase
DK878_RS03830	ENOG4105BZF	Glycosyl transferase (Group 1
DK878_RS03845	ENOG4105C22	threonyL-tRNA synthetase
DK878_RS03850	ENOG4105DRP	amino acid AbC transporter
DK878_RS03855	ENOG4105EAD	ABC transporter
DK878_RS03860	ENOG4107RP9	extracellular solute-binding protein, family 3
DK878_RS03870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DK878_RS03880	ENOG4105Q2H	domain protein
DK878_RS03890	ENOG4105C5H	ABC transporter
DK878_RS03895	ENOG4107RF6	penicillin-binding protein
DK878_RS03900	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
DK878_RS03905	ENOG4105CPF	Cell wall formation (By similarity)
DK878_RS03925	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
DK878_RS03935	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DK878_RS03950	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
DK878_RS03970	ENOG4105ETE	Transcriptional regulator (LacI family
DK878_RS03980	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
DK878_RS03985	ENOG4107YY3	extracellular solute-binding protein family 1
DK878_RS03990	ENOG4107R3K	hydrolase
DK878_RS03995	ENOG4105CNU	cell division protein FtsK
DK878_RS04000	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
DK878_RS04035	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DK878_RS04040	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
DK878_RS04045	ENOG4105QNR	S1 RNA binding domain protein
DK878_RS04060	ENOG4106E6V	UPF0346 protein
DK878_RS04075	ENOG4108Z0Z	intracellular protease Pfpi family
DK878_RS04080	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DK878_RS04085	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
DK878_RS04090	ENOG4105EAC	phosphoserine phosphatase
DK878_RS04095	ENOG4107XGZ	Hydrolase
DK878_RS04100	ENOG4105BZW	Glycerate kinase
DK878_RS04215	ENOG4105PAD	Hydrolase
DK878_RS04225	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
DK878_RS04240	ENOG4107FQX	Alpha-acetolactate decarboxylase
DK878_RS04250	ENOG4105CID	antiterminator
DK878_RS04255	ENOG4105C5Y	PTS System
DK878_RS04275	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DK878_RS04295	ENOG4107UWA	esterase
DK878_RS04310	ENOG4105C5H	ABC transporter
DK878_RS04320	ENOG4105DHI	Methyltransferase
DK878_RS04325	ENOG4105F1K	Glutamine amidotransferase
DK878_RS04330	ENOG4105DMS	mur ligase
DK878_RS04345	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DK878_RS04350	ENOG4105C5H	ABC transporter
DK878_RS04355	ENOG4108I0C	methyltransferase
DK878_RS04375	ENOG4108RG0	uracil-dna glycosylase
DK878_RS04385	ENOG4108V0P	LemA family
DK878_RS04390	ENOG4105DZ6	Band 7 protein
DK878_RS04405	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
DK878_RS04420	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
DK878_RS04430	ENOG4105E66	phosphoriboisomerase A
DK878_RS04435	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
DK878_RS04445	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
DK878_RS04450	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DK878_RS04455	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
DK878_RS04465	ENOG4105CSA	Coproporphyrinogen iii oxidase
DK878_RS04480	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
DK878_RS04490	ENOG4105VCC	30S ribosomal protein S21
DK878_RS04495	ENOG4105CMR	udp-glucose 4-epimerase
DK878_RS04500	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
DK878_RS04505	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
DK878_RS04510	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DK878_RS04515	ENOG4105VG1	fes assembly suf system protein
DK878_RS04550	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
DK878_RS04560	ENOG4105CZV	ABC transporter
DK878_RS04565	ENOG4106S9K	Transcriptional regulator
DK878_RS04575	ENOG4105CTQ	phosphohexokinase
DK878_RS04580	ENOG4105CA9	Pyruvate kinase
DK878_RS04595	ENOG4107VFR	oxidoreductase
DK878_RS04615	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DK878_RS04620	ENOG4105E5Q	amino acid AbC transporter
DK878_RS04625	ENOG4105CDA	abc transporter atp-binding protein
DK878_RS04630	ENOG4106TNF	Periplasmic binding protein
DK878_RS04640	ENOG4105D4A	Cell wall formation (By similarity)
DK878_RS04645	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DK878_RS04650	ENOG4105F38	ABC transporter, permease
DK878_RS04655	ENOG4105D38	putrescine abc transporter
DK878_RS04660	ENOG4108HM4	ABC transporter
DK878_RS04665	ENOG4105CMQ	Chloride channel
DK878_RS04680	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
DK878_RS04685	ENOG4105CSM	endonuclease III
DK878_RS04695	ENOG4107QMU	Mate efflux family protein
DK878_RS04700	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
DK878_RS04705	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
DK878_RS04710	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DK878_RS04715	ENOG4105E98	transcriptional regulator DeoR family
DK878_RS04720	ENOG4105DE4	1-phosphofructokinase
DK878_RS04725	ENOG4105DM4	PTS System
DK878_RS04735	ENOG4105EPR	degv family
DK878_RS04740	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
DK878_RS04745	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DK878_RS04750	ENOG4105C5H	ABC transporter
DK878_RS04760	ENOG4105DKQ	ROK family
DK878_RS04775	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
DK878_RS04780	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
DK878_RS04785	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
DK878_RS04800	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
DK878_RS04825	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
DK878_RS04830	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DK878_RS04835	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DK878_RS04845	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DK878_RS04855	ENOG41065S2	pneumococcal vaccine antigen
DK878_RS04865	ENOG4105EMU	Dehydrogenase
DK878_RS04890	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
DK878_RS04895	ENOG4107SQC	5-methylcytosine-specific restriction enzyme subunit McrC
DK878_RS04910	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
DK878_RS04915	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DK878_RS04930	ENOG4105I1F	Resistance protein
DK878_RS04935	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
DK878_RS04950	ENOG4105CJZ	response regulator
DK878_RS05015	ENOG41086D8	Transcriptional regulator
DK878_RS05020	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
DK878_RS05025	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
DK878_RS05065	ENOG4105DRS	transport system, permease
DK878_RS05070	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
DK878_RS05090	ENOG4105DET	Rhamnulokinase
DK878_RS05105	ENOG4105MU5	relaxase mobilization nuclease domain protein
DK878_RS05115	ENOG4108XTP	Transcriptional regulator
DK878_RS05120	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DK878_RS05155	ENOG4105DVF	Cytosine-specific methyltransferase
DK878_RS05180	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
DK878_RS05215	ENOG4105EKQ	RNA-directed DNA polymerase
DK878_RS05240	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DK878_RS05290	ENOG4105DA5	(ABC) transporter
DK878_RS05310	ENOG4105MU5	relaxase mobilization nuclease domain protein
DK878_RS05330	ENOG4108WZA	zeta toxin
DK878_RS05390	ENOG4105WT3	Transcriptional regulator
DK878_RS05425	ENOG4105VEM	Conserved domain protein
DK878_RS05430	ENOG4105FA0	parb-like partition protein
DK878_RS05535	ENOG4105EKQ	RNA-directed DNA polymerase
DK878_RS05570	ENOG4105DVF	Cytosine-specific methyltransferase
DK878_RS05585	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
DK878_RS05590	ENOG4108VZM	50s ribosomal protein L10
DK878_RS05595	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DK878_RS05600	ENOG4105C79	DNA protecting protein DprA
DK878_RS05605	ENOG4108UW5	maltose o-acetyltransferase
DK878_RS05610	ENOG4105VPX	protein, conserved in bacteria
DK878_RS05615	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
DK878_RS05620	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
DK878_RS05630	ENOG4108UT2	hemolysin iii
DK878_RS05640	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DK878_RS05645	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
DK878_RS05655	ENOG4108Z03	MAF-like protein
DK878_RS05660	ENOG4105CGH	5'-nucleotidase
DK878_RS05670	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
DK878_RS05675	ENOG4105CKK	Glycosyl transferase, family 2
DK878_RS05685	ENOG4105F0N	pyrophosphate phospho-hydrolase
DK878_RS05690	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
DK878_RS05695	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
DK878_RS05720	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
DK878_RS05730	ENOG4107R0W	ABC transporter
DK878_RS05735	ENOG4107R0W	ABC transporter
DK878_RS05775	ENOG4106PMH	Extracellular solute-binding protein family 3
DK878_RS05780	ENOG4105CDA	abc transporter atp-binding protein
DK878_RS05790	ENOG4105C5H	ABC transporter
DK878_RS05815	ENOG4105CK1	PTS System
DK878_RS05820	ENOG4105VCP	PTS System
DK878_RS05825	ENOG4105CID	antiterminator
DK878_RS05830	ENOG4105D2M	Aldolase
DK878_RS05835	ENOG4105DE4	1-phosphofructokinase
DK878_RS05845	ENOG4105RSI	Galactose-6-phosphate isomerase subunit LacA
DK878_RS05850	ENOG4105E98	transcriptional regulator DeoR family
DK878_RS05885	ENOG4105CEN	a g-specific adenine glycosylase
DK878_RS05895	ENOG4105BZ1	(ABC) transporter
DK878_RS05900	ENOG4105BZ1	(ABC) transporter
DK878_RS05905	ENOG4108IJ2	phosphate acetyltransferase
DK878_RS05910	ENOG4105EMS	pseudouridine synthase
DK878_RS05915	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DK878_RS05925	ENOG4105MIX	Adenylate cyclase
DK878_RS05935	ENOG4105C3J	Cysteine desulfurase
DK878_RS05950	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
DK878_RS05965	ENOG4108Z6X	(sortase) family
DK878_RS05970	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DK878_RS05975	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DK878_RS05980	ENOG4105NAE	bifunctional deaminase-reductase domain protein
DK878_RS05990	ENOG4105NAE	bifunctional deaminase-reductase domain protein
DK878_RS06000	ENOG4105UIB	(ABC) transporter
DK878_RS06005	ENOG4108JQ9	ABC transporter
DK878_RS06010	ENOG4105DIH	basic membrane
DK878_RS06025	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
DK878_RS06030	ENOG4107Y49	methyltransferase
DK878_RS06035	ENOG4105CS9	pantothenic acid kinase
DK878_RS06040	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
DK878_RS06050	ENOG4105US7	Histidine kinase
DK878_RS06055	ENOG4108STX	response regulator
DK878_RS06070	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
DK878_RS06075	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DK878_RS06080	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DK878_RS06085	ENOG4105E2Z	phosphate ABC transporter (Permease
DK878_RS06090	ENOG4105C8U	phosphate abc transporter
DK878_RS06100	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DK878_RS06105	ENOG4105ECY	inositol monophosphatase
DK878_RS06110	ENOG4105WBI	UPF0223 protein
DK878_RS06115	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
DK878_RS06125	ENOG4105DTN	riboflavin biosynthesis protein ribF
DK878_RS06130	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DK878_RS06170	ENOG410667J	hydrolase
DK878_RS06175	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
DK878_RS06190	ENOG4105VUN	Transcriptional regulator
DK878_RS06210	ENOG4105KA3	membrAne
DK878_RS06215	ENOG4105FS7	Transcriptional regulator
DK878_RS06235	ENOG4105CY2	Citrate transporter
DK878_RS06255	ENOG4105EUJ	GTP cyclohydrolase i
DK878_RS06260	ENOG4108Z4K	mutator MutT protein
DK878_RS06285	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
DK878_RS06300	ENOG4105D17	glycoside hydrolase, family 3 domain protein
DK878_RS06305	ENOG4105D17	glycoside hydrolase, family 3 domain protein
DK878_RS06315	ENOG4105DMW	Dehydrogenase reductase
DK878_RS06320	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
DK878_RS06330	ENOG4108UHU	Aldolase
DK878_RS06340	ENOG4105CNT	hydrolase family 2
DK878_RS06350	ENOG4105CT4	transporter
DK878_RS06355	ENOG4105ZT7	DNA-entry nuclease
DK878_RS06365	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DK878_RS06375	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
DK878_RS06380	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
DK878_RS06385	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
DK878_RS06390	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
DK878_RS06400	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
DK878_RS06405	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
DK878_RS06410	ENOG4105ZA1	atp synthase
DK878_RS06415	ENOG4105CBD	Diacylglycerol kinase
DK878_RS06430	ENOG4108PJD	permease
DK878_RS06435	ENOG4108NNR	transporter substrate-binding protein
DK878_RS06440	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
DK878_RS06455	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DK878_RS06460	ENOG410667J	hydrolase
DK878_RS06465	ENOG4108HCJ	Hydrolase
DK878_RS06470	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
DK878_RS06500	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
DK878_RS06505	ENOG4105KRI	phosphocarrier protein (HPr
DK878_RS06510	ENOG4108HMX	isocitrate dehydrogenase (NADP)
DK878_RS06515	ENOG4105BZN	citrate synthase
DK878_RS06520	ENOG4108I0Z	Aconitate hydratase
DK878_RS06525	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
DK878_RS06530	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DK878_RS06535	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DK878_RS06540	ENOG4108M60	Transcriptional regulator
DK878_RS06555	ENOG4106AM8	polysaccharide lyase family 8
DK878_RS06565	ENOG4105F3R	pts system mannose fructose sorbose family iid
DK878_RS06575	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
DK878_RS06580	ENOG4105EP8	Glycosyl Hydrolase Family 88
DK878_RS06640	ENOG4105VZ8	Transcriptional regulator
DK878_RS06660	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DK878_RS06670	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
DK878_RS06700	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DK878_RS06710	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DK878_RS06715	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DK878_RS06720	ENOG4105E2X	shikimate dehydrogenase
DK878_RS06725	ENOG4105D49	3-dehydroquinate synthase
DK878_RS06735	ENOG4105C7J	ABC transporter, permease
DK878_RS06750	ENOG4105D2M	Aldolase
DK878_RS06755	ENOG4105CE4	GlcNAc 6-P deacetylase
DK878_RS06765	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DK878_RS06770	ENOG4105D6E	homoserine dehydrogenase
DK878_RS06775	ENOG4107BJW	polysaccharide deacetylase
DK878_RS06780	ENOG4105BZ1	(ABC) transporter
DK878_RS06790	ENOG4105VB6	UPF0109 protein
DK878_RS06795	ENOG4105K5M	30s ribosomal protein S16
DK878_RS06805	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
DK878_RS06810	ENOG4107YX5	Pfam:DUF548
DK878_RS06820	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
DK878_RS06825	ENOG4105CXT	aspartate transcarbamylase
DK878_RS06830	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
DK878_RS06840	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
DK878_RS06845	ENOG4105C34	Pseudouridine synthase
DK878_RS06855	ENOG4105DUM	transcriptional regulator, lysR family
DK878_RS06865	ENOG4105K46	50S ribosomal protein l27
DK878_RS06870	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
DK878_RS06875	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
DK878_RS06880	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
DK878_RS06885	ENOG4105C3J	Cysteine desulfurase
DK878_RS06910	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DK878_RS06935	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DK878_RS06945	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DK878_RS06960	ENOG4105MZU	cell filamentation protein
DK878_RS06965	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DK878_RS06975	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
DK878_RS06980	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DK878_RS07050	ENOG4105C4R	Atp-dependent dna helicase
DK878_RS07065	ENOG4105DPN	Oligoendopeptidase f
DK878_RS07185	ENOG4105WZB	UPF0342 protein
DK878_RS07190	ENOG4105EVN	Prephenate dehydrogenase
DK878_RS07195	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DK878_RS07200	ENOG4105FF2	Type I DHQase
DK878_RS07205	ENOG4105DR4	Methyltransferase
DK878_RS07225	ENOG4105VJV	50s ribosomal protein L35
DK878_RS07235	ENOG4105CAT	Cytidine monophosphate kinase
DK878_RS07265	ENOG4105CKK	Glycosyl transferase, family 2
DK878_RS07285	ENOG4105X1N	Glycosyl transferase family 8
DK878_RS07305	ENOG4105EY8	ABC transporter
DK878_RS07345	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
DK878_RS07350	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
DK878_RS07365	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
DK878_RS07375	ENOG4105EGD	dinuclear metal center protein, YbgI family
DK878_RS07395	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
DK878_RS07405	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
DK878_RS07410	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
DK878_RS07420	ENOG4108IXY	short-chain dehydrogenase reductase
DK878_RS07425	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
DK878_RS07435	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DK878_RS07440	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
DK878_RS07450	ENOG4105DJ2	Major Facilitator Superfamily
DK878_RS07460	ENOG4105C9A	Phoh family
DK878_RS07480	ENOG4105SFS	phosphoesterase RecJ domain protein
DK878_RS07500	ENOG4107R4J	Chloride channel
DK878_RS07510	ENOG4105CGH	5'-nucleotidase
DK878_RS07515	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DK878_RS07520	ENOG4105TQK	DNA polymerase iii, delta' subunit
DK878_RS07530	ENOG4105WPN	DNA integration recombination invertion protein
DK878_RS07535	ENOG4108IV0	ABC, transporter
DK878_RS07540	ENOG4105C0Z	ABC transporter
DK878_RS07545	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
DK878_RS07550	ENOG4105C32	Amino acid ABC transporter (Permease)
DK878_RS07555	ENOG4105CP9	extracellular ligand-binding receptor
DK878_RS07570	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
DK878_RS07575	ENOG4105CG3	alpha amylase, catalytic region
DK878_RS07595	ENOG4107YY3	extracellular solute-binding protein family 1
DK878_RS07605	ENOG4108R6W	Transcriptional regulator, ARAC family
DK878_RS07610	ENOG4105C87	Aminotransferase class I and II
DK878_RS07615	ENOG4105C28	cystathionine
DK878_RS07635	ENOG410836F	Transposase
DK878_RS07640	ENOG41060K3	Methyltransferase
DK878_RS07645	ENOG4105VC4	domain protein
DK878_RS07665	ENOG41082BM	Transcriptional regulator, arsr family
DK878_RS07670	ENOG4105C1J	atp-dependent rna helicase
DK878_RS07675	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
DK878_RS07680	ENOG4105KWG	Pfam:DUF1696
DK878_RS07720	ENOG4108YZ4	nudix hydrolase
DK878_RS07725	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DK878_RS07740	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
DK878_RS07765	ENOG4108HVR	ABC transporter, permease
DK878_RS07770	ENOG4105C19	ABC transporter
DK878_RS07790	ENOG4105CHM	Aminotransferase
DK878_RS07800	ENOG4105E90	ABC transporter
DK878_RS07805	ENOG4108IJ8	ABC transporter
DK878_RS07825	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
DK878_RS07830	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
DK878_RS07835	ENOG4105DG6	mannose-6-phosphate isomerase
DK878_RS07850	ENOG410906U	SprT-like
DK878_RS07875	ENOG4105CV8	reductase
DK878_RS07880	ENOG410807C	QueT transporter
DK878_RS07885	ENOG4105WH5	Teichoic acid glycosylation protein
DK878_RS07895	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
DK878_RS07905	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DK878_RS07910	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
DK878_RS07915	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
DK878_RS07920	ENOG4108UK2	deaminase
DK878_RS07940	ENOG4105DER	m42 family
DK878_RS07955	ENOG4105C6E	dna polymerase iii
DK878_RS07960	ENOG4108ZGC	gaf domain protein
DK878_RS07980	ENOG4105EE0	oxidoreductase
DK878_RS07985	ENOG4105FDU	atp-dependent rna helicase
DK878_RS07990	ENOG4108ZJ4	polysaccharide deacetylase
DK878_RS08005	ENOG4105CHU	acetyl-coa acetyltransferase
DK878_RS08010	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
DK878_RS08045	ENOG4105K70	DNA-binding protein
DK878_RS08055	ENOG41090WU	lipolytic protein G-D-S-L family
DK878_RS08060	ENOG4108RCR	degv family
DK878_RS08065	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DK878_RS08070	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
DK878_RS08075	ENOG4105DX0	Hemolysin A
DK878_RS08085	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DK878_RS08090	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DK878_RS08095	ENOG4105CGZ	zinc metallopeptidase
DK878_RS08100	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
DK878_RS08105	ENOG4105BZU	Histidine kinase
DK878_RS08110	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DK878_RS08130	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
DK878_RS08140	ENOG4105F1A	Pyruvate formate-lyase
DK878_RS08145	ENOG4105C37	(CBS) domain
DK878_RS08150	ENOG4105DKW	ABC transporter
DK878_RS08165	ENOG4105DAP	Nicotinate phosphoribosyltransferase
DK878_RS08170	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
DK878_RS08185	ENOG4105MMD	transcriptional regulator
DK878_RS08190	ENOG41063PX	domain protein
DK878_RS08195	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
DK878_RS08200	ENOG4106H78	methyltransferase
DK878_RS08210	ENOG4105WZW	rhodanese family
DK878_RS08225	ENOG4105BZU	Histidine kinase
DK878_RS08230	ENOG4105KCT	ABC transporter
DK878_RS08235	ENOG4108M15	ABC transporter
DK878_RS08250	ENOG4105KJF	protein tyrosine phosphatase
DK878_RS08260	ENOG4105EXC	Acyl-transferase
DK878_RS08265	ENOG410841Q	phosphoesterase PA-phosphatase related protein
DK878_RS08270	ENOG4108SAX	Membrane
DK878_RS08285	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
DK878_RS08290	ENOG4105FE9	pseudouridine synthase
DK878_RS08295	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
DK878_RS08300	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
DK878_RS08305	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
DK878_RS08325	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
DK878_RS08330	ENOG4105VXM	UPF0154 protein
DK878_RS08340	ENOG4105CTZ	aminopeptidase c
DK878_RS08345	ENOG4105HFZ	Membrane
DK878_RS08355	ENOG4108RWN	rrna methyltransferase
DK878_RS08370	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
DK878_RS08385	ENOG4105DFU	Cell wall formation (By similarity)
DK878_RS08410	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
DK878_RS08430	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
DK878_RS08440	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DK878_RS08445	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
DK878_RS08455	ENOG4105C3M	thioredoxin reductase
DK878_RS08465	ENOG4105C1J	atp-dependent rna helicase
DK878_RS08485	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DK878_RS08490	ENOG4105CJN	penicillin-binding protein
DK878_RS08500	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
DK878_RS08555	ENOG41088B0	Major membrane immunogen
DK878_RS08560	ENOG4105EAH	synthase
DK878_RS08595	ENOG4105VPS	UPF0291 protein
DK878_RS08600	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
DK878_RS08620	ENOG4108UMI	ABC transporter, permease
DK878_RS08625	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
DK878_RS08630	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DK878_RS08635	ENOG4105D01	(LipO)protein
DK878_RS08645	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
DK878_RS08650	ENOG4105SYT	Methylenetetrahydrofolate reductase
DK878_RS08655	ENOG4105C7N	Xanthine uracil vitamin C permease
DK878_RS08660	ENOG4108KP7	hydrolase
DK878_RS08670	ENOG4105ETZ	PTS System
DK878_RS08675	ENOG4105F3R	pts system mannose fructose sorbose family iid
DK878_RS08710	ENOG4105DZR	Type I site-specific deoxyribonuclease
DK878_RS08745	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
DK878_RS08755	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DK878_RS08770	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DK878_RS08775	ENOG4105CHR	reductase
DK878_RS08780	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
DK878_RS08785	ENOG4105EA8	2-Nitropropane dioxygenase
DK878_RS08795	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DK878_RS08805	ENOG4105CGU	Enoyl-CoA hydratase
DK878_RS08810	ENOG4107YBY	Hydrolase
DK878_RS08815	ENOG4105CFH	Aspartokinase
DK878_RS08820	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DK878_RS08825	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
DK878_RS08830	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DK878_RS08840	ENOG4105EVU	fructokinase
DK878_RS08845	ENOG4105C5Y	PTS System
DK878_RS08855	ENOG4105ETE	Transcriptional regulator (LacI family
DK878_RS08860	ENOG4105M7K	Involved in the transcription termination process (By similarity)
DK878_RS08875	ENOG4105DC7	peptidase M24
DK878_RS08880	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DK878_RS08895	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
DK878_RS08900	ENOG4108UUM	single-stranded DNA-binding protein
DK878_RS08910	ENOG4105DF9	Lipoate-protein, ligase
DK878_RS08915	ENOG4105CS2	ec 3.2.1.21
DK878_RS08930	ENOG4105CS2	ec 3.2.1.21
DK878_RS08935	ENOG4105CK1	PTS System
DK878_RS08945	ENOG4105VCP	PTS System
DK878_RS08950	ENOG4105EMD	TRANSCRIPTIONal
DK878_RS08965	ENOG4105W3H	MtN3 and saliva related transmembrane protein
DK878_RS08970	ENOG4105CS2	ec 3.2.1.21
DK878_RS08975	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
DK878_RS08980	ENOG4105CS2	ec 3.2.1.21
DK878_RS08985	ENOG4106AXJ	AraC family transcriptional regulator
DK878_RS08995	ENOG4105C5Y	PTS System
DK878_RS09000	ENOG4105CID	antiterminator
DK878_RS09010	ENOG4107QN2	dihydrolipoyl dehydrogenase
DK878_RS09015	ENOG4105C7S	Dehydrogenase
DK878_RS09020	ENOG4105CPP	Dehydrogenase, E1 component
DK878_RS09025	ENOG4107RUY	(E1 component), alpha subunit
DK878_RS09030	ENOG4105EN6	Membrane
DK878_RS09045	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
DK878_RS09050	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DK878_RS09060	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
DK878_RS09065	ENOG4105CHV	Transcription elongation factor NusA
DK878_RS09075	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
DK878_RS09095	ENOG4105K59	histidine triad (HIT) protein
DK878_RS09105	ENOG4108KGH	TRANSCRIPTIONal
DK878_RS09115	ENOG4105K8N	protein family UPF0079, ATPase
DK878_RS09135	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DK878_RS09140	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DK878_RS09145	ENOG4108JQ7	(ABC) transporter
DK878_RS09155	ENOG4105DEF	Extracellular solute-binding protein, family 5
DK878_RS09170	ENOG4108UNV	SUF system FeS assembly protein, NifU family
DK878_RS09175	ENOG4105C9B	Cysteine desulfurase
DK878_RS09180	ENOG4105JRK	feS assembly protein SufD
DK878_RS09190	ENOG4105ESV	Glycosyl transferase, family 4
DK878_RS09195	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DK878_RS09200	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
DK878_RS09205	ENOG4105E5Q	amino acid AbC transporter
DK878_RS09210	ENOG4105CDA	abc transporter atp-binding protein
DK878_RS09225	ENOG4105C7B	Threonine dehydratase
DK878_RS09230	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DK878_RS09235	ENOG4108ZP8	Acetolactate synthase small subunit
DK878_RS09260	ENOG4105C01	Dihydroxy-acid dehydratase
DK878_RS09270	ENOG4105VG1	fes assembly suf system protein
DK878_RS09290	ENOG4105CB5	ATP-dependent DNA helicase recG
DK878_RS09320	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DK878_RS09325	ENOG4105EPR	degv family
DK878_RS09335	ENOG4105C2N	RNA methyltransferase TrmH family group 3
DK878_RS09350	ENOG4108IJ9	(ABC) transporter
DK878_RS09360	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DK878_RS09380	ENOG4105D7W	serine acetyltransferase
DK878_RS09385	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DK878_RS09390	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
DK878_RS09395	ENOG4108RDQ	ABC transporter
DK878_RS09450	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DK878_RS09460	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DK878_RS09480	ENOG4105CK1	PTS System
DK878_RS09495	ENOG4105VCP	PTS System
DK878_RS09510	ENOG4105C88	aminopeptidase
DK878_RS09525	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
DK878_RS09530	ENOG4105CMT	Dihydroxyacetone kinase
DK878_RS09540	ENOG4105CMT	Dihydroxyacetone kinase
DK878_RS09545	ENOG4108UTZ	Dihydroxyacetone kinase
DK878_RS09550	ENOG4105VDH	Dihydroxyacetone kinase
DK878_RS09555	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DK878_RS09560	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DK878_RS09570	ENOG4105KNE	Phosphatidate cytidylyltransferase
DK878_RS09575	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DK878_RS09580	ENOG4105VIE	preprotein translocase, subunit YajC
DK878_RS09590	ENOG4105D9M	gamma-glutamylcysteine synthetase
DK878_RS09600	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
DK878_RS09605	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
DK878_RS09610	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
DK878_RS09615	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DK878_RS09650	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
DK878_RS09690	ENOG4105BZ4	penicillin-binding protein
DK878_RS09695	ENOG4105CAY	ferredoxin--nadp reductase
DK878_RS09700	ENOG4108YBP	pseudouridine synthase
DK878_RS09840	ENOG4105DFT	pur operon repressor
DK878_RS09860	ENOG4105FJ0	thiamine
DK878_RS09865	ENOG4105DJV	ribulose-phosphate 3-epimerase
DK878_RS09870	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DK878_RS09880	ENOG4105BZ1	(ABC) transporter
DK878_RS09905	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
DK878_RS09930	ENOG4105F8V	Hydrolase, tatD family
DK878_RS09940	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
DK878_RS09950	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
DK878_RS09955	ENOG4105CH7	arginosuccinase
DK878_RS09960	ENOG4105CDH	Citrulline--aspartate ligase
DK878_RS09965	ENOG4105RNB	
DK878_RS10025	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
DK878_RS10030	ENOG4105BZ1	(ABC) transporter
DK878_RS10035	ENOG4105BZ1	(ABC) transporter
DK878_RS10045	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DK878_RS10050	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
DK878_RS10060	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
DK878_RS10065	ENOG4105CH2	amidohydrolase
DK878_RS10080	ENOG4107S1Q	Phosphatase
DK878_RS10105	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DK878_RS10130	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
DK878_RS10155	ENOG4108IUM	Glycogen debranching enzyme
DK878_RS10160	ENOG4105FKQ	transcriptional regulator
DK878_RS10165	ENOG4105CDA	abc transporter atp-binding protein
DK878_RS10170	ENOG4105DRP	amino acid AbC transporter
DK878_RS10185	ENOG41068JE	domain protein
DK878_RS10190	ENOG4105CK1	PTS System
DK878_RS10200	ENOG4105VCP	PTS System
DK878_RS10210	ENOG4105EMD	TRANSCRIPTIONal
DK878_RS10220	ENOG4105CS2	ec 3.2.1.21
DK878_RS10225	ENOG4105F8D	glycoside hydrolase family 4
DK878_RS10235	ENOG4105C9K	Endothelin-converting enzyme 1
DK878_RS10240	ENOG4105CC5	ABC transporter
DK878_RS10245	ENOG4105CC5	ABC transporter
DK878_RS10250	ENOG4105DIK	(ABC) transporter
DK878_RS10260	ENOG4105DSE	periplasmic solute binding protein
DK878_RS10275	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
DK878_RS10285	ENOG4105CGH	5'-nucleotidase
DK878_RS10305	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
DK878_RS10325	ENOG4105D1H	recombination factor protein RarA
DK878_RS10340	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
DK878_RS10350	ENOG4105CGH	5'-nucleotidase
DK878_RS10355	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
DK878_RS10360	ENOG4105CDA	abc transporter atp-binding protein
DK878_RS10365	ENOG4105E5Q	amino acid AbC transporter
DK878_RS10390	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
DK878_RS10395	ENOG4105C75	arginyL-tRNA synthetase
DK878_RS10415	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
DK878_RS10420	ENOG4107FKK	extracellular solute-binding protein family 1
DK878_RS10425	ENOG4105D56	permease protein
DK878_RS10430	ENOG4105EG2	ABC transporter, permease
DK878_RS10435	ENOG4108VP7	maltodextrose utilization protein MalA
DK878_RS10440	ENOG4105FKQ	transcriptional regulator
DK878_RS10445	ENOG4108IUM	Glycogen debranching enzyme
DK878_RS10450	ENOG4105MTF	NrdI protein
DK878_RS10455	ENOG4107AYK	membrAne
DK878_RS10460	ENOG4105C9M	aspartyl-trna synthetase
DK878_RS10465	ENOG4107YB6	acetyltransferase, (GNAT) family
DK878_RS10470	ENOG4107RGM	aldo keto reductase
DK878_RS10475	ENOG4105K64	Glycosyl transferase, family 2
DK878_RS10495	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DK878_RS10505	ENOG4105CDU	Replicative dna helicase
DK878_RS10510	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
DK878_RS10520	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
DK878_RS10525	ENOG4105M6F	mutator MutT protein
DK878_RS10530	ENOG4105KVH	Transcriptional regulator
DK878_RS10540	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
DK878_RS10550	ENOG4105EJQ	L-serine dehydratase
DK878_RS10560	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
DK878_RS10565	ENOG4108JJB	ABC transporter
DK878_RS10570	ENOG4108JJB	ABC transporter
DK878_RS10575	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
DK878_RS10675	ENOG4105VTR	Integrase
DK878_RS10685	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DK878_RS10695	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DK878_RS10710	ENOG4105C5H	ABC transporter
DK878_RS10740	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
DK878_RS10745	ENOG4105C0H	protease
DK878_RS10750	ENOG4105FA0	parb-like partition protein