locus-tag	class	description
DK878_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DK878_RS00010	COG0592	DNA-directed DNA polymerase activity
DK878_RS00030	COG0012	GTP binding
DK878_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
DK878_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DK878_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DK878_RS00060	COG0037	tRNA processing
DK878_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DK878_RS00180	COG1792	Involved in formation and maintenance of cell shape
DK878_RS00195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DK878_RS00200	COG0436	Aminotransferase
DK878_RS00205	COG1381	Involved in DNA repair and RecF pathway recombination
DK878_RS00210	COG0416	fatty acid biosynthetic process
DK878_RS00215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK878_RS00225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DK878_RS00240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DK878_RS00245	COG0138	bifunctional purine biosynthesis protein purh
DK878_RS00270	COG0151	Belongs to the GarS family
DK878_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DK878_RS00290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DK878_RS00320	COG1131	(ABC) transporter
DK878_RS00330	COG1132	(ABC) transporter
DK878_RS00340	COG2255	four-way junction helicase activity
DK878_RS00350	COG0546	phosphoglycolate phosphatase activity
DK878_RS00360	COG0285	dihydrofolate synthase activity
DK878_RS00370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DK878_RS00375	COG0632	four-way junction helicase activity
DK878_RS00380	COG0519	Catalyzes the synthesis of GMP from XMP
DK878_RS00395	COG1393	Belongs to the ArsC family
DK878_RS00400	COG4472	Bacterial protein of unknown function (DUF965)
DK878_RS00405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DK878_RS00410	COG3906	Belongs to the UPF0473 family
DK878_RS00425	COG0051	transcription antitermination factor activity, RNA binding
DK878_RS00430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DK878_RS00435	COG0088	Forms part of the polypeptide exit tunnel
DK878_RS00440	COG0089	rRNA binding
DK878_RS00445	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DK878_RS00450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DK878_RS00455	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DK878_RS00460	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DK878_RS00465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DK878_RS00470	COG0255	Belongs to the universal ribosomal protein uL29 family
DK878_RS00475	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DK878_RS00480	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DK878_RS00485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DK878_RS00490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DK878_RS00495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DK878_RS00500	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DK878_RS00505	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DK878_RS00510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DK878_RS00515	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DK878_RS00520	COG1841	ribosomal large subunit assembly
DK878_RS00530	COG0201	protein transport
DK878_RS00535	COG0563	adenylate kinase activity
DK878_RS00540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DK878_RS00545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DK878_RS00550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DK878_RS00560	COG0202	RNA polymerase activity
DK878_RS00675	COG1121	(ABC) transporter
DK878_RS00680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK878_RS00685	COG0803	Belongs to the bacterial solute-binding protein 9 family
DK878_RS00685	COG3443	Belongs to the bacterial solute-binding protein 9 family
DK878_RS00710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK878_RS00715	COG0085	RNA polymerase activity
DK878_RS00720	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DK878_RS00730	COG1619	proteins homologs of microcin C7 resistance protein MccF
DK878_RS00735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DK878_RS00740	COG1459	type II secretion system
DK878_RS00745	COG4537	Required for transformation and DNA binding
DK878_RS00775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DK878_RS00785	COG0285	dihydrofolate synthase activity
DK878_RS00790	COG1363	Peptidase, m42
DK878_RS00800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DK878_RS00810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK878_RS00835	COG0459	protein refolding
DK878_RS00845	COG0049	tRNA binding
DK878_RS00850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DK878_RS00855	COG3590	peptidase
DK878_RS00865	COG0126	phosphoglycerate kinase activity
DK878_RS00875	COG0789	Transcriptional regulator
DK878_RS00880	COG0174	glutamine synthetase
DK878_RS00895	COG1214	PFAM Peptidase M22, glycoprotease
DK878_RS00905	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DK878_RS00910	COG2207	Transcriptional regulator
DK878_RS00920	COG1175	transmembrane transport
DK878_RS00925	COG0395	ABC-type sugar transport system, permease component
DK878_RS00945	COG2855	membrane
DK878_RS00955	COG1131	(ABC) transporter
DK878_RS00965	COG2081	HI0933 family
DK878_RS00970	COG2723	6-phospho-beta-galactosidase activity
DK878_RS00980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK878_RS00995	COG3959	Transketolase, thiamine diphosphate binding domain
DK878_RS01000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DK878_RS01005	COG0584	glycerophosphoryl diester phosphodiesterase
DK878_RS01010	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DK878_RS01015	COG2222	sugar isomerase
DK878_RS01035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DK878_RS01045	COG3942	CHAP domain
DK878_RS01050	COG1882	Formate acetyltransferase
DK878_RS01065	COG2910	NAD(P)H-binding
DK878_RS01085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK878_RS01120	COG0363	glucosamine-6-phosphate deaminase activity
DK878_RS01125	COG2217	Heavy metal translocating P-type atpase
DK878_RS01135	COG2217	Heavy metal translocating P-type atpase
DK878_RS01140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DK878_RS01145	COG0681	Belongs to the peptidase S26 family
DK878_RS01165	COG0366	Alpha amylase catalytic
DK878_RS01170	COG1263	PTS System
DK878_RS01170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK878_RS01175	COG2188	Transcriptional regulator
DK878_RS01190	COG1193	negative regulation of DNA recombination
DK878_RS01255	COG3118	belongs to the thioredoxin family
DK878_RS01265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DK878_RS01265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DK878_RS01315	COG1115	amino acid carrier protein
DK878_RS01320	COG0668	transmembrane transport
DK878_RS01330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DK878_RS01335	COG0167	dihydroorotate dehydrogenase activity
DK878_RS01340	COG2843	Capsule synthesis protein
DK878_RS01345	COG0561	phosphatase activity
DK878_RS01360	COG1131	(ABC) transporter
DK878_RS01365	COG1309	transcriptional regulator
DK878_RS01405	COG1346	cytolysis
DK878_RS01410	COG2116	formate transmembrane transporter activity
DK878_RS01415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DK878_RS01420	COG0433	COG0433 Predicted ATPase
DK878_RS01425	COG0494	nUDIX hydrolase
DK878_RS01445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK878_RS01450	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DK878_RS01455	COG0124	histidyl-tRNA synthetase
DK878_RS01460	COG1064	alcohol dehydrogenase
DK878_RS01465	COG1454	alcohol dehydrogenase
DK878_RS01465	COG1012	belongs to the aldehyde dehydrogenase family
DK878_RS01475	COG4988	ABC transporter
DK878_RS01480	COG1132	(ABC) transporter
DK878_RS01495	COG1129	ABC transporter
DK878_RS01500	COG0534	Mate efflux family protein
DK878_RS01505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DK878_RS01520	COG1304	FMN binding
DK878_RS01525	COG1132	(ABC) transporter
DK878_RS01530	COG1132	(ABC) transporter
DK878_RS01535	COG3830	Belongs to the UPF0237 family
DK878_RS01540	COG2848	UPF0210 protein
DK878_RS01545	COG0588	phosphoglycerate mutase activity
DK878_RS01550	COG1420	regulation of RNA biosynthetic process
DK878_RS01555	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DK878_RS01560	COG0443	Heat shock 70 kDa protein
DK878_RS01565	COG0484	heat shock protein binding
DK878_RS01570	COG0095	Lipoate-protein ligase
DK878_RS01580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK878_RS01585	COG0765	amino acid transport
DK878_RS01600	COG3655	Transcriptional regulator
DK878_RS01610	COG2217	Heavy metal translocating P-type atpase
DK878_RS01635	COG4475	Protein of unknown function (DUF436)
DK878_RS01660	COG4221	oxidoreductase activity
DK878_RS01665	COG1902	pentaerythritol trinitrate reductase activity
DK878_RS01665	COG0446	pyridine nucleotide-disulphide oxidoreductase
DK878_RS01685	COG0544	peptidyl-prolyl cis-trans isomerase activity
DK878_RS01715	COG3343	RNA polymerase activity
DK878_RS01720	COG0504	CTP synthase activity
DK878_RS01730	COG0191	fructose-bisphosphate aldolase activity
DK878_RS01735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DK878_RS01770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DK878_RS01800	COG0436	Aminotransferase
DK878_RS01805	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DK878_RS01810	COG1335	isochorismatase
DK878_RS01820	COG0335	large ribosomal subunit rRNA binding
DK878_RS01830	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DK878_RS01835	COG0154	amidase activity
DK878_RS01840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DK878_RS01850	COG1609	Transcriptional regulator
DK878_RS01855	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DK878_RS01860	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DK878_RS01875	COG3142	Participates in the control of copper homeostasis
DK878_RS01890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK878_RS01895	COG1534	Rna-binding protein
DK878_RS01900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DK878_RS01905	COG1713	HD superfamily hydrolase involved in NAD metabolism
DK878_RS01920	COG0799	negative regulation of ribosome biogenesis
DK878_RS01925	COG2226	methyltransferase
DK878_RS01940	COG0789	Transcriptional regulator
DK878_RS01950	COG0242	peptide deformylase activity
DK878_RS01960	COG1640	4-alpha-glucanotransferase
DK878_RS01965	COG0058	SHG alpha-glucan phosphorylase activity
DK878_RS01980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK878_RS01980	COG2190	(PTS) system
DK878_RS01980	COG1263	PTS System
DK878_RS01995	COG0217	transcriptional regulatory protein
DK878_RS02005	COG4720	Psort location CytoplasmicMembrane, score
DK878_RS02025	COG1122	ATPase activity
DK878_RS02040	COG0357	Ribosomal RNA small subunit methyltransferase G
DK878_RS02045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK878_RS02050	COG3331	DNA recombination
DK878_RS02055	COG4474	Belongs to the UPF0398 family
DK878_RS02060	COG3599	regulation of cell shape
DK878_RS02070	COG0116	Belongs to the methyltransferase superfamily
DK878_RS02080	COG1854	S-ribosylhomocysteine lyase activity
DK878_RS02085	COG1418	mRNA catabolic process
DK878_RS02095	COG1758	RNA polymerase activity
DK878_RS02100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DK878_RS02105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DK878_RS02110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK878_RS02110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK878_RS02115	COG0631	protein serine/threonine phosphatase activity
DK878_RS02120	COG0515	serine threonine protein kinase
DK878_RS02120	COG2815	serine threonine protein kinase
DK878_RS02145	COG1098	S1 RNA binding domain
DK878_RS02155	COG4974	Belongs to the 'phage' integrase family
DK878_RS02320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DK878_RS02325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DK878_RS02330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DK878_RS02345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DK878_RS02350	COG3022	response to hydroperoxide
DK878_RS02360	COG3944	biosynthesis protein
DK878_RS02370	COG4464	protein tyrosine phosphatase activity
DK878_RS02385	COG0438	transferase activity, transferring glycosyl groups
DK878_RS02400	COG1216	Glycosyl transferase, family 2
DK878_RS02400	COG1442	glycosyl transferase family 8
DK878_RS02405	COG1442	glycosyl transferase family 8
DK878_RS02405	COG1216	Glycosyl transferase, family 2
DK878_RS02435	COG2089	acid synthase
DK878_RS02450	COG2755	lipolytic protein G-D-S-L family
DK878_RS02450	COG1083	cytidylyl-transferase
DK878_RS02515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DK878_RS02520	COG0077	Prephenate dehydratase
DK878_RS02530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK878_RS02540	COG0562	UDP-galactopyranose mutase
DK878_RS02545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DK878_RS02560	COG0436	Aminotransferase
DK878_RS02580	COG0534	Mate efflux family protein
DK878_RS02585	COG0251	oxidation-reduction process
DK878_RS02590	COG1660	Displays ATPase and GTPase activities
DK878_RS02595	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DK878_RS02600	COG1481	regulation of sporulation
DK878_RS02615	COG0454	-acetyltransferase
DK878_RS02620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DK878_RS02625	COG0549	Belongs to the carbamate kinase family
DK878_RS02630	COG1288	antiporter activity
DK878_RS02635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK878_RS02640	COG3064	Membrane
DK878_RS02640	COG3583	domain protein
DK878_RS02640	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DK878_RS02645	COG1438	arginine binding
DK878_RS02650	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DK878_RS02655	COG0363	glucosamine-6-phosphate deaminase activity
DK878_RS02690	COG1696	Membrane protein involved in D-alanine export
DK878_RS02695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DK878_RS02700	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DK878_RS02710	COG0435	Glutathione S-transferase
DK878_RS02715	COG1187	pseudouridine synthase activity
DK878_RS02720	COG0386	Belongs to the glutathione peroxidase family
DK878_RS02725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK878_RS02730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DK878_RS02735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DK878_RS02740	COG1120	ATPase activity
DK878_RS02745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DK878_RS02750	COG0204	Acyl-transferase
DK878_RS02755	COG1596	polysaccharide export
DK878_RS02755	COG1555	photosystem II stabilization
DK878_RS02760	COG2333	competence protein COMEC
DK878_RS02760	COG0658	competence protein
DK878_RS02770	COG0517	IMP dehydrogenase activity
DK878_RS02785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK878_RS02790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DK878_RS02795	COG0470	DNA polymerase III
DK878_RS02800	COG4467	Involved in initiation control of chromosome replication
DK878_RS02810	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DK878_RS02820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DK878_RS02825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DK878_RS02830	COG1393	Belongs to the ArsC family
DK878_RS02840	COG0708	Exodeoxyribonuclease III
DK878_RS02850	COG0531	amino acid
DK878_RS02880	COG1061	Type III restriction enzyme res subunit
DK878_RS02905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DK878_RS02910	COG4684	Psort location CytoplasmicMembrane, score
DK878_RS02915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DK878_RS02925	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DK878_RS02965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DK878_RS02970	COG1349	DNA-binding transcription factor activity
DK878_RS02980	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK878_RS02985	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK878_RS02990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK878_RS02995	COG1882	Formate acetyltransferase
DK878_RS03015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DK878_RS03020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DK878_RS03035	COG1739	Uncharacterized protein family UPF0029
DK878_RS03040	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DK878_RS03125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DK878_RS03135	COG3557	Belongs to the UPF0374 family
DK878_RS03145	COG2188	Transcriptional regulator
DK878_RS03150	COG2188	Transcriptional regulator
DK878_RS03160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK878_RS03170	COG3716	PTS system mannose fructose sorbose family IID component
DK878_RS03180	COG2017	converts alpha-aldose to the beta-anomer
DK878_RS03195	COG0346	lactoylglutathione lyase activity
DK878_RS03230	COG0494	nUDIX hydrolase
DK878_RS03260	COG0681	Belongs to the peptidase S26 family
DK878_RS03295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DK878_RS03310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DK878_RS03315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DK878_RS03320	COG1799	cell septum assembly
DK878_RS03335	COG3599	regulation of cell shape
DK878_RS03365	COG0542	response to heat
DK878_RS03370	COG4703	Protein of unknown function (DUF1797)
DK878_RS03375	COG0765	amino acid transport
DK878_RS03385	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DK878_RS03420	COG0789	Transcriptional regulator
DK878_RS03445	COG4443	Transcriptional Coactivator p15 (PC4)
DK878_RS03450	COG1268	BioY protein
DK878_RS03460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DK878_RS03470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DK878_RS03475	COG1136	(ABC) transporter
DK878_RS03480	COG0577	efflux transmembrane transporter activity
DK878_RS03500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DK878_RS03510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DK878_RS03520	COG3859	Proton-coupled thiamine transporter YuaJ
DK878_RS03540	COG0772	Belongs to the SEDS family
DK878_RS03545	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DK878_RS03560	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DK878_RS03565	COG0149	triose-phosphate isomerase activity
DK878_RS03575	COG1078	dGTPase activity
DK878_RS03610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DK878_RS03620	COG2884	Cell division ATP-binding protein ftsE
DK878_RS03625	COG2177	Part of the ABC transporter FtsEX involved in
DK878_RS03650	COG1132	(ABC) transporter
DK878_RS03655	COG1132	(ABC) transporter
DK878_RS03660	COG1011	Hydrolase
DK878_RS03680	COG1737	Transcriptional regulator
DK878_RS03690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DK878_RS03695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DK878_RS03700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DK878_RS03705	COG0237	dephospho-CoA kinase activity
DK878_RS03710	COG2814	Major facilitator Superfamily
DK878_RS03715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK878_RS03725	COG0557	exoribonuclease II activity
DK878_RS03730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DK878_RS03735	COG1063	alcohol dehydrogenase
DK878_RS03750	COG2217	Heavy metal translocating P-type atpase
DK878_RS03755	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DK878_RS03775	COG3547	Transposase (IS116 IS110 IS902 family)
DK878_RS03785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK878_RS03785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DK878_RS03795	COG1832	CoA-binding protein
DK878_RS03805	COG0343	queuine tRNA-ribosyltransferase activity
DK878_RS03815	COG1609	Transcriptional regulator
DK878_RS03830	COG0438	transferase activity, transferring glycosyl groups
DK878_RS03845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DK878_RS03850	COG0765	amino acid transport
DK878_RS03855	COG0765	amino acid transport
DK878_RS03860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK878_RS03870	COG0745	RESPONSE REGULATOR receiver
DK878_RS03880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DK878_RS03890	COG0488	(ABC) transporter
DK878_RS03895	COG0768	penicillin binding
DK878_RS03900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DK878_RS03905	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK878_RS03925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK878_RS03935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DK878_RS03950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DK878_RS03970	COG1609	Transcriptional regulator
DK878_RS03975	COG4209	transmembrane transport
DK878_RS03980	COG0395	ABC-type sugar transport system, permease component
DK878_RS03985	COG1653	transport
DK878_RS03990	COG1621	beta-fructofuranosidase activity
DK878_RS03995	COG1674	ftsk spoiiie
DK878_RS03995	COG0697	spore germination
DK878_RS04000	COG0346	lactoylglutathione lyase activity
DK878_RS04025	COG0625	glutathione transferase activity
DK878_RS04030	COG2244	polysaccharide biosynthetic process
DK878_RS04035	COG0528	UMP kinase activity
DK878_RS04040	COG0233	cytoplasmic translational termination
DK878_RS04045	COG2996	Protein conserved in bacteria
DK878_RS04060	COG4479	Belongs to the UPF0346 family
DK878_RS04070	COG0772	Belongs to the SEDS family
DK878_RS04075	COG0693	protein deglycase activity
DK878_RS04080	COG0187	DNA topoisomerase II activity
DK878_RS04085	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DK878_RS04090	COG0560	Phosphoserine phosphatase
DK878_RS04215	COG1011	Hydrolase
DK878_RS04225	COG2706	6-phosphogluconolactonase activity
DK878_RS04230	COG0628	permease
DK878_RS04240	COG3527	Alpha-acetolactate decarboxylase
DK878_RS04245	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DK878_RS04250	COG3711	transcriptional antiterminator
DK878_RS04255	COG2190	(PTS) system
DK878_RS04255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK878_RS04255	COG1263	PTS System
DK878_RS04275	COG3842	ATPase activity
DK878_RS04310	COG0488	(ABC) transporter
DK878_RS04320	COG2226	methyltransferase
DK878_RS04325	COG3442	glutamine amidotransferase
DK878_RS04330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DK878_RS04345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DK878_RS04350	COG0488	(ABC) transporter
DK878_RS04355	COG2226	methyltransferase
DK878_RS04375	COG1573	uracil-dna glycosylase
DK878_RS04385	COG1704	LemA family
DK878_RS04390	COG2268	Band 7 protein
DK878_RS04405	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DK878_RS04415	COG1518	maintenance of DNA repeat elements
DK878_RS04430	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DK878_RS04435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DK878_RS04445	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DK878_RS04450	COG0813	purine-nucleoside phosphorylase activity
DK878_RS04455	COG0058	SHG alpha-glucan phosphorylase activity
DK878_RS04465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DK878_RS04475	COG1051	belongs to the nudix hydrolase family
DK878_RS04480	COG0647	UMP catabolic process
DK878_RS04490	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DK878_RS04495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DK878_RS04500	COG1970	mechanosensitive ion channel activity
DK878_RS04505	COG0358	DNA primase activity
DK878_RS04510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DK878_RS04515	COG2151	metal-sulfur cluster biosynthetic enzyme
DK878_RS04550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DK878_RS04560	COG1131	(ABC) transporter
DK878_RS04565	COG2188	Transcriptional regulator
DK878_RS04575	COG0205	6-phosphofructokinase activity
DK878_RS04580	COG0469	pyruvate kinase activity
DK878_RS04595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DK878_RS04600	COG2755	lipolytic protein G-D-S-L family
DK878_RS04600	COG0657	acetylesterase activity
DK878_RS04615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DK878_RS04620	COG0765	amino acid transport
DK878_RS04625	COG1126	abc transporter atp-binding protein
DK878_RS04630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK878_RS04640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DK878_RS04645	COG3842	ATPase activity
DK878_RS04650	COG1176	ABC-type spermidine putrescine transport system, permease component I
DK878_RS04655	COG1177	transmembrane transport
DK878_RS04665	COG0038	chloride channel
DK878_RS04680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DK878_RS04685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DK878_RS04695	COG0534	Mate efflux family protein
DK878_RS04700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DK878_RS04705	COG0336	Belongs to the RNA methyltransferase TrmD family
DK878_RS04710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DK878_RS04715	COG1349	DNA-binding transcription factor activity
DK878_RS04720	COG1105	Belongs to the carbohydrate kinase PfkB family
DK878_RS04725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK878_RS04725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DK878_RS04725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK878_RS04735	COG1307	EDD domain protein, DegV family
DK878_RS04740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DK878_RS04745	COG0617	tRNA 3'-terminal CCA addition
DK878_RS04750	COG0488	(ABC) transporter
DK878_RS04760	COG1940	carbohydrate kinase activity
DK878_RS04775	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DK878_RS04780	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DK878_RS04785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DK878_RS04800	COG0481	GTPase activity
DK878_RS04825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DK878_RS04830	COG2890	protein-(glutamine-N5) methyltransferase activity
DK878_RS04835	COG0009	L-threonylcarbamoyladenylate synthase
DK878_RS04845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DK878_RS04855	COG0741	lytic transglycosylase activity
DK878_RS04865	COG4221	oxidoreductase activity
DK878_RS04890	COG1401	restriction endodeoxyribonuclease activity
DK878_RS04895	COG4268	DNA restriction-modification system
DK878_RS04905	COG2188	Transcriptional regulator
DK878_RS04910	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DK878_RS04915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DK878_RS04930	COG1660	Displays ATPase and GTPase activities
DK878_RS04935	COG4974	Belongs to the 'phage' integrase family
DK878_RS04950	COG0745	RESPONSE REGULATOR receiver
DK878_RS04970	COG1136	(ABC) transporter
DK878_RS05005	COG2382	esterase
DK878_RS05015	COG2207	Transcriptional regulator
DK878_RS05015	COG3708	Transcriptional regulator
DK878_RS05020	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DK878_RS05025	COG0647	UMP catabolic process
DK878_RS05065	COG0395	ABC-type sugar transport system, permease component
DK878_RS05070	COG1175	transmembrane transport
DK878_RS05090	COG1070	Carbohydrate kinase
DK878_RS05105	COG3843	relaxase mobilization nuclease domain protein
DK878_RS05120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DK878_RS05140	COG0827	DNA restriction-modification system
DK878_RS05155	COG0270	DNA (cytosine-5-)-methyltransferase activity
DK878_RS05180	COG1705	Flagellar rod assembly protein muramidase FlgJ
DK878_RS05180	COG3942	CHAP domain
DK878_RS05215	COG3344	reverse transcriptase
DK878_RS05240	COG4974	Belongs to the 'phage' integrase family
DK878_RS05290	COG1131	(ABC) transporter
DK878_RS05310	COG3843	relaxase mobilization nuclease domain protein
DK878_RS05325	COG0613	PHP domain protein
DK878_RS05330	COG0542	response to heat
DK878_RS05335	COG1396	sequence-specific DNA binding
DK878_RS05390	COG1396	sequence-specific DNA binding
DK878_RS05425	COG4443	Transcriptional Coactivator p15 (PC4)
DK878_RS05430	COG1475	DNA binding
DK878_RS05535	COG3344	reverse transcriptase
DK878_RS05570	COG0270	DNA (cytosine-5-)-methyltransferase activity
DK878_RS05585	COG0222	ribosome binding
DK878_RS05590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DK878_RS05595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DK878_RS05600	COG0758	DNA mediated transformation
DK878_RS05605	COG0110	maltose O-acetyltransferase activity
DK878_RS05610	COG1937	Protein conserved in bacteria
DK878_RS05620	COG0446	pyridine nucleotide-disulphide oxidoreductase
DK878_RS05630	COG1272	protein, Hemolysin III
DK878_RS05640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DK878_RS05645	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DK878_RS05655	COG0424	maF-like protein
DK878_RS05660	COG0737	Belongs to the 5'-nucleotidase family
DK878_RS05670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DK878_RS05675	COG0463	Glycosyl transferase, family 2
DK878_RS05685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DK878_RS05690	COG0284	orotidine-5'-phosphate decarboxylase activity
DK878_RS05695	COG0167	dihydroorotate dehydrogenase activity
DK878_RS05720	COG0297	glycogen (starch) synthase activity
DK878_RS05730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK878_RS05735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK878_RS05780	COG1126	abc transporter atp-binding protein
DK878_RS05790	COG0488	(ABC) transporter
DK878_RS05795	COG2873	o-acetylhomoserine
DK878_RS05815	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK878_RS05815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK878_RS05825	COG3711	transcriptional antiterminator
DK878_RS05830	COG3684	Belongs to the aldolase LacD family
DK878_RS05835	COG1105	Belongs to the carbohydrate kinase PfkB family
DK878_RS05840	COG0698	ribose 5-phosphate isomerase
DK878_RS05845	COG0698	ribose 5-phosphate isomerase
DK878_RS05850	COG1349	DNA-binding transcription factor activity
DK878_RS05880	COG1396	sequence-specific DNA binding
DK878_RS05885	COG1194	a g-specific adenine glycosylase
DK878_RS05895	COG1132	(ABC) transporter
DK878_RS05900	COG1132	(ABC) transporter
DK878_RS05905	COG0280	phosphate acetyltransferase
DK878_RS05910	COG0564	pseudouridine synthase activity
DK878_RS05915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DK878_RS05920	COG2357	RelA SpoT domain protein
DK878_RS05925	COG4116	CYTH
DK878_RS05935	COG1104	cysteine desulfurase activity
DK878_RS05950	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DK878_RS05955	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK878_RS05965	COG3764	Sortase (surface protein transpeptidase)
DK878_RS05970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DK878_RS05975	COG0039	L-malate dehydrogenase activity
DK878_RS05980	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DK878_RS05990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DK878_RS06010	COG1744	ABC transporter substrate-binding protein PnrA-like
DK878_RS06025	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DK878_RS06030	COG2813	Specifically methylates the guanine in position
DK878_RS06035	COG1072	(Pantothenic acid kinase))
DK878_RS06040	COG0268	Binds directly to 16S ribosomal RNA
DK878_RS06050	COG5002	protein histidine kinase activity
DK878_RS06055	COG0745	RESPONSE REGULATOR receiver
DK878_RS06070	COG0704	Plays a role in the regulation of phosphate uptake
DK878_RS06075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK878_RS06080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DK878_RS06085	COG0581	inorganic phosphate transmembrane transporter activity
DK878_RS06090	COG0573	inorganic phosphate transmembrane transporter activity
DK878_RS06100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DK878_RS06100	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DK878_RS06105	COG0483	inositol monophosphate 1-phosphatase activity
DK878_RS06110	COG4476	Belongs to the UPF0223 family
DK878_RS06115	COG1393	Belongs to the ArsC family
DK878_RS06120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DK878_RS06125	COG0196	riboflavin kinase activity
DK878_RS06130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DK878_RS06170	COG0561	phosphatase activity
DK878_RS06175	COG2195	Cleaves the N-terminal amino acid of tripeptides
DK878_RS06190	COG1695	Transcriptional regulator
DK878_RS06210	COG3759	membrane
DK878_RS06215	COG1846	Transcriptional regulator
DK878_RS06230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DK878_RS06235	COG2610	gluconate transmembrane transporter activity
DK878_RS06255	COG0302	gtp cyclohydrolase
DK878_RS06260	COG1051	belongs to the nudix hydrolase family
DK878_RS06285	COG0072	phenylalanine-tRNA ligase activity
DK878_RS06285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK878_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
DK878_RS06320	COG1312	Catalyzes the dehydration of D-mannonate
DK878_RS06330	COG0800	Aldolase
DK878_RS06340	COG3250	beta-galactosidase activity
DK878_RS06350	COG2211	Major facilitator Superfamily
DK878_RS06365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK878_RS06375	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DK878_RS06380	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DK878_RS06385	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DK878_RS06390	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DK878_RS06395	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DK878_RS06400	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DK878_RS06405	COG0356	it plays a direct role in the translocation of protons across the membrane
DK878_RS06415	COG1597	lipid kinase activity
DK878_RS06430	COG0701	Predicted permease
DK878_RS06435	COG3689	TIGRFAM TIGR03943 family protein
DK878_RS06440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DK878_RS06455	COG0552	protein localization to endoplasmic reticulum
DK878_RS06460	COG0561	phosphatase activity
DK878_RS06465	COG0561	phosphatase activity
DK878_RS06470	COG1196	nuclear chromosome segregation
DK878_RS06505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK878_RS06510	COG0538	isocitrate dehydrogenase activity
DK878_RS06515	COG0372	Belongs to the citrate synthase family
DK878_RS06520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DK878_RS06525	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DK878_RS06530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DK878_RS06535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DK878_RS06540	COG1609	Transcriptional regulator
DK878_RS06555	COG5492	domain, Protein
DK878_RS06565	COG3716	PTS system mannose fructose sorbose family IID component
DK878_RS06575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK878_RS06580	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DK878_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
DK878_RS06640	COG1476	TRANSCRIPTIONal
DK878_RS06660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DK878_RS06670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DK878_RS06675	COG4122	O-methyltransferase activity
DK878_RS06700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK878_RS06700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DK878_RS06710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DK878_RS06715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DK878_RS06720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DK878_RS06725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DK878_RS06730	COG1116	anion transmembrane transporter activity
DK878_RS06730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DK878_RS06735	COG4120	Belongs to the binding-protein-dependent transport system permease family
DK878_RS06750	COG3684	Belongs to the aldolase LacD family
DK878_RS06765	COG0083	homoserine kinase activity
DK878_RS06775	COG0726	polysaccharide deacetylase
DK878_RS06780	COG1132	(ABC) transporter
DK878_RS06795	COG0228	four-way junction DNA binding
DK878_RS06805	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DK878_RS06810	COG2136	Putative SAM-dependent methyltransferase
DK878_RS06810	COG2521	methyltransferase
DK878_RS06820	COG0505	Belongs to the CarA family
DK878_RS06825	COG0540	Belongs to the ATCase OTCase family
DK878_RS06830	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DK878_RS06840	COG2824	Alkylphosphonate utilization operon protein PhnA
DK878_RS06845	COG0564	pseudouridine synthase activity
DK878_RS06865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DK878_RS06870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DK878_RS06875	COG1114	Component of the transport system for branched-chain amino acids
DK878_RS06880	COG0301	tRNA thio-modification
DK878_RS06885	COG1104	cysteine desulfurase activity
DK878_RS06910	COG0539	negative regulation of cytoplasmic translation
DK878_RS06935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DK878_RS06945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DK878_RS06960	COG2184	nucleotidyltransferase activity
DK878_RS06965	COG0187	DNA topoisomerase II activity
DK878_RS06975	COG1074	ATP-dependent DNA helicase activity
DK878_RS06980	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DK878_RS07010	COG1131	(ABC) transporter
DK878_RS07040	COG1011	Hydrolase
DK878_RS07050	COG0210	DNA helicase
DK878_RS07065	COG1164	Oligoendopeptidase f
DK878_RS07185	COG3679	Belongs to the UPF0342 family
DK878_RS07190	COG0287	Prephenate dehydrogenase
DK878_RS07195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DK878_RS07200	COG0710	3-dehydroquinate dehydratase activity
DK878_RS07205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DK878_RS07210	COG1368	sulfuric ester hydrolase activity
DK878_RS07225	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DK878_RS07235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DK878_RS07280	COG1216	Glycosyl transferase, family 2
DK878_RS07280	COG1442	glycosyl transferase family 8
DK878_RS07285	COG1442	glycosyl transferase family 8
DK878_RS07315	COG1216	Glycosyl transferase, family 2
DK878_RS07315	COG1442	glycosyl transferase family 8
DK878_RS07345	COG1091	dTDP-4-dehydrorhamnose reductase activity
DK878_RS07350	COG1088	dTDP-glucose 4,6-dehydratase activity
DK878_RS07365	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DK878_RS07375	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DK878_RS07380	COG2384	SAM-dependent methyltransferase
DK878_RS07395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK878_RS07405	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DK878_RS07405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DK878_RS07410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DK878_RS07420	COG0300	oxidoreductase activity
DK878_RS07425	COG1234	tRNA 3'-trailer cleavage
DK878_RS07435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DK878_RS07440	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DK878_RS07450	COG2807	transmembrane transport
DK878_RS07455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK878_RS07460	COG1702	phosphate starvation-inducible protein PhoH
DK878_RS07480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DK878_RS07485	COG0716	FMN binding
DK878_RS07495	COG0287	Prephenate dehydrogenase
DK878_RS07495	COG1605	Chorismate mutase
DK878_RS07500	COG0038	chloride channel
DK878_RS07510	COG0737	Belongs to the 5'-nucleotidase family
DK878_RS07515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DK878_RS07520	COG1466	dna polymerase III delta subunit
DK878_RS07555	COG0683	leucine binding
DK878_RS07570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DK878_RS07575	COG0366	Alpha amylase catalytic
DK878_RS07585	COG0395	ABC-type sugar transport system, permease component
DK878_RS07590	COG1175	transmembrane transport
DK878_RS07595	COG1653	transport
DK878_RS07605	COG2207	Transcriptional regulator
DK878_RS07610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DK878_RS07615	COG0626	cystathionine gamma-synthase activity
DK878_RS07635	COG3547	Transposase (IS116 IS110 IS902 family)
DK878_RS07640	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DK878_RS07645	COG2827	Endonuclease containing a URI domain
DK878_RS07665	COG0640	Transcriptional regulator
DK878_RS07670	COG0513	Belongs to the DEAD box helicase family
DK878_RS07675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK878_RS07720	COG0494	nUDIX hydrolase
DK878_RS07725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DK878_RS07735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DK878_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
DK878_RS07765	COG0577	efflux transmembrane transporter activity
DK878_RS07770	COG1136	(ABC) transporter
DK878_RS07775	COG2205	protein histidine kinase activity
DK878_RS07790	COG0436	Aminotransferase
DK878_RS07800	COG1174	glycine betaine transport
DK878_RS07805	COG0517	IMP dehydrogenase activity
DK878_RS07805	COG1125	glycine betaine transport
DK878_RS07825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DK878_RS07830	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DK878_RS07835	COG1482	cell wall glycoprotein biosynthetic process
DK878_RS07850	COG3091	SprT-like family
DK878_RS07855	COG2183	response to ionizing radiation
DK878_RS07875	COG0656	L-ascorbic acid biosynthetic process
DK878_RS07880	COG4708	membrane
DK878_RS07885	COG2246	polysaccharide biosynthetic process
DK878_RS07895	COG0024	Methionine aminopeptidase
DK878_RS07905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DK878_RS07910	COG2249	NAD(P)H dehydrogenase (quinone) activity
DK878_RS07915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DK878_RS07920	COG2131	deaminase
DK878_RS07940	COG1363	Peptidase, m42
DK878_RS07955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DK878_RS07960	COG1956	GAF domain-containing protein
DK878_RS07980	COG0673	inositol 2-dehydrogenase activity
DK878_RS07985	COG0513	Belongs to the DEAD box helicase family
DK878_RS07990	COG0726	polysaccharide deacetylase
DK878_RS08005	COG0183	Belongs to the thiolase family
DK878_RS08010	COG3425	synthase
DK878_RS08045	COG0776	regulation of translation
DK878_RS08055	COG2755	lipolytic protein G-D-S-L family
DK878_RS08060	COG1307	EDD domain protein, DegV family
DK878_RS08065	COG0497	DNA recombination
DK878_RS08070	COG1438	arginine binding
DK878_RS08075	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DK878_RS08085	COG1722	exodeoxyribonuclease VII activity
DK878_RS08090	COG1570	exodeoxyribonuclease VII activity
DK878_RS08095	COG2321	neutral zinc metallopeptidase
DK878_RS08100	COG1755	Isoprenylcysteine carboxyl methyltransferase
DK878_RS08105	COG5002	protein histidine kinase activity
DK878_RS08110	COG0745	RESPONSE REGULATOR receiver
DK878_RS08130	COG1227	inorganic diphosphatase activity
DK878_RS08140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DK878_RS08145	COG1253	flavin adenine dinucleotide binding
DK878_RS08150	COG1119	ATPase activity
DK878_RS08155	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DK878_RS08165	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DK878_RS08170	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DK878_RS08185	COG4470	Protein conserved in bacteria
DK878_RS08190	COG3480	Lon protease (S16) C-terminal proteolytic domain
DK878_RS08195	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DK878_RS08200	COG0742	ribosomal rna small subunit methyltransferase
DK878_RS08210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DK878_RS08215	COG4483	Protein conserved in bacteria
DK878_RS08220	COG2197	response regulator
DK878_RS08225	COG4585	Histidine kinase
DK878_RS08225	COG2203	Gaf domain
DK878_RS08230	COG0842	Transport permease protein
DK878_RS08235	COG1131	(ABC) transporter
DK878_RS08250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DK878_RS08260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DK878_RS08260	COG2755	lipolytic protein G-D-S-L family
DK878_RS08265	COG0671	phosphoesterase, PA-phosphatase related
DK878_RS08270	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DK878_RS08285	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DK878_RS08290	COG1187	pseudouridine synthase activity
DK878_RS08295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DK878_RS08300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DK878_RS08305	COG0582	viral genome integration into host DNA
DK878_RS08325	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DK878_RS08330	COG3763	UPF0154 protein
DK878_RS08340	COG3579	cysteine-type endopeptidase activity
DK878_RS08355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK878_RS08360	COG1254	Belongs to the acylphosphatase family
DK878_RS08370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DK878_RS08375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DK878_RS08385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DK878_RS08395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DK878_RS08410	COG1160	GTP binding
DK878_RS08420	COG1484	DNA-dependent DNA replication
DK878_RS08430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DK878_RS08435	COG0628	permease
DK878_RS08440	COG0745	RESPONSE REGULATOR receiver
DK878_RS08445	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DK878_RS08455	COG0492	ferredoxin-NADP+ reductase activity
DK878_RS08465	COG0513	Belongs to the DEAD box helicase family
DK878_RS08485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK878_RS08490	COG0768	penicillin binding
DK878_RS08500	COG0275	rRNA processing
DK878_RS08555	COG4939	FMN-binding domain protein
DK878_RS08560	COG0142	geranyltranstransferase activity
DK878_RS08565	COG1252	NADH dehydrogenase
DK878_RS08575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DK878_RS08580	COG0569	domain protein
DK878_RS08585	COG0534	Mate efflux family protein
DK878_RS08595	COG4224	UPF0291 protein
DK878_RS08600	COG0751	glycine-tRNA ligase activity
DK878_RS08625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DK878_RS08630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DK878_RS08635	COG1464	Belongs to the NlpA lipoprotein family
DK878_RS08640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK878_RS08645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DK878_RS08650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DK878_RS08655	COG2252	PERMEase
DK878_RS08660	COG0561	phosphatase activity
DK878_RS08670	COG3715	PTS system
DK878_RS08675	COG3716	PTS system mannose fructose sorbose family IID component
DK878_RS08700	COG3177	Filamentation induced by cAMP protein fic
DK878_RS08710	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DK878_RS08745	COG0825	malonyl-CoA metabolic process
DK878_RS08755	COG0439	Biotin carboxylase
DK878_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
DK878_RS08780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DK878_RS08785	COG2070	2-Nitropropane dioxygenase
DK878_RS08795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DK878_RS08805	COG1024	Enoyl-CoA hydratase
DK878_RS08810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DK878_RS08815	COG0527	aspartate kinase activity
DK878_RS08820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DK878_RS08825	COG0736	holo-[acyl-carrier-protein] synthase activity
DK878_RS08830	COG0653	protein targeting
DK878_RS08840	COG1940	carbohydrate kinase activity
DK878_RS08845	COG2190	(PTS) system
DK878_RS08845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK878_RS08845	COG1263	PTS System
DK878_RS08850	COG1621	beta-fructofuranosidase activity
DK878_RS08855	COG1609	Transcriptional regulator
DK878_RS08860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DK878_RS08875	COG0006	proline dipeptidase activity
DK878_RS08880	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DK878_RS08895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DK878_RS08900	COG0629	single-stranded DNA binding
DK878_RS08910	COG0095	Lipoate-protein ligase
DK878_RS08915	COG2723	6-phospho-beta-galactosidase activity
DK878_RS08930	COG2723	6-phospho-beta-galactosidase activity
DK878_RS08935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK878_RS08945	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK878_RS08950	COG3711	transcriptional antiterminator
DK878_RS08950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK878_RS08965	COG4095	Psort location CytoplasmicMembrane, score
DK878_RS08970	COG2723	6-phospho-beta-galactosidase activity
DK878_RS08975	COG0346	lactoylglutathione lyase activity
DK878_RS08980	COG2723	6-phospho-beta-galactosidase activity
DK878_RS08985	COG2207	Transcriptional regulator
DK878_RS08985	COG1917	Cupin 2, conserved barrel domain protein
DK878_RS08995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DK878_RS08995	COG1263	PTS System
DK878_RS08995	COG2190	(PTS) system
DK878_RS09000	COG3711	transcriptional antiterminator
DK878_RS09015	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK878_RS09020	COG0022	dehydrogenase e1 component
DK878_RS09020	COG0508	dehydrogenase complex catalyzes the overall conversion of
DK878_RS09025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DK878_RS09030	COG2860	membrane
DK878_RS09045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DK878_RS09050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DK878_RS09060	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DK878_RS09065	COG0195	Participates in both transcription termination and antitermination
DK878_RS09075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DK878_RS09085	COG4473	ABC transporter
DK878_RS09090	COG1131	(ABC) transporter
DK878_RS09095	COG0537	adenosine 5'-monophosphoramidase activity
DK878_RS09105	COG1316	TRANSCRIPTIONal
DK878_RS09115	COG0802	atpase or kinase
DK878_RS09135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DK878_RS09140	COG0601	transmembrane transport
DK878_RS09145	COG4608	Belongs to the ABC transporter superfamily
DK878_RS09155	COG0747	negative chemotaxis
DK878_RS09160	COG1686	Belongs to the peptidase S11 family
DK878_RS09175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DK878_RS09180	COG0719	Fe-S assembly protein
DK878_RS09190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DK878_RS09195	COG4862	establishment of competence for transformation
DK878_RS09200	COG1968	undecaprenyl-diphosphatase activity
DK878_RS09205	COG0765	amino acid transport
DK878_RS09210	COG1126	abc transporter atp-binding protein
DK878_RS09225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DK878_RS09230	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DK878_RS09235	COG0440	acetolactate synthase activity
DK878_RS09240	COG0028	Belongs to the TPP enzyme family
DK878_RS09260	COG0129	dihydroxy-acid dehydratase activity
DK878_RS09270	COG2151	metal-sulfur cluster biosynthetic enzyme
DK878_RS09320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DK878_RS09335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DK878_RS09350	COG3842	ATPase activity
DK878_RS09360	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DK878_RS09380	COG1045	serine acetyltransferase
DK878_RS09385	COG1185	polyribonucleotide nucleotidyltransferase activity
DK878_RS09390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DK878_RS09395	COG1131	(ABC) transporter
DK878_RS09430	COG1187	pseudouridine synthase activity
DK878_RS09450	COG0242	peptide deformylase activity
DK878_RS09460	COG0066	3-isopropylmalate dehydratase activity
DK878_RS09480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK878_RS09490	COG2188	Transcriptional regulator
DK878_RS09495	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK878_RS09510	COG2309	aminopeptidase activity
DK878_RS09525	COG2176	DNA-directed DNA polymerase activity
DK878_RS09530	COG2376	Dihydroxyacetone kinase
DK878_RS09540	COG2376	Dihydroxyacetone kinase
DK878_RS09545	COG1461	Dihydroxyacetone kinase
DK878_RS09550	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DK878_RS09555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DK878_RS09560	COG0442	prolyl-tRNA aminoacylation
DK878_RS09570	COG4589	Belongs to the CDS family
DK878_RS09575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DK878_RS09580	COG1862	Preprotein translocase
DK878_RS09590	COG2918	glutathione biosynthetic process
DK878_RS09590	COG1181	Belongs to the D-alanine--D-alanine ligase family
DK878_RS09600	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DK878_RS09605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DK878_RS09610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DK878_RS09615	COG0542	response to heat
DK878_RS09620	COG4463	regulation of RNA biosynthetic process
DK878_RS09640	COG1388	LysM domain
DK878_RS09640	COG4932	domain protein
DK878_RS09650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DK878_RS09685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DK878_RS09690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DK878_RS09695	COG0492	ferredoxin-NADP+ reductase activity
DK878_RS09700	COG0564	pseudouridine synthase activity
DK878_RS09840	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DK878_RS09860	COG1564	THIamine pyrophosphokinase
DK878_RS09870	COG1162	GTPase activity
DK878_RS09880	COG1132	(ABC) transporter
DK878_RS09905	COG4115	mRNA cleavage
DK878_RS09930	COG0084	hydrolase, TatD family'
DK878_RS09940	COG1847	R3H domain protein
DK878_RS09950	COG0594	ribonuclease P activity
DK878_RS09955	COG0165	Argininosuccinate lyase
DK878_RS09960	COG0137	argininosuccinate synthase activity
DK878_RS09970	COG1827	regulation of RNA biosynthetic process
DK878_RS10025	COG0756	dUTP diphosphatase activity
DK878_RS10030	COG1132	(ABC) transporter
DK878_RS10035	COG1132	(ABC) transporter
DK878_RS10045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DK878_RS10050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DK878_RS10055	COG0705	Rhomboid family
DK878_RS10060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DK878_RS10065	COG1473	amidohydrolase
DK878_RS10070	COG2171	N-acyltransferase activity
DK878_RS10080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DK878_RS10105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DK878_RS10130	COG3623	hexulose-6-phosphate isomerase
DK878_RS10155	COG1523	belongs to the glycosyl hydrolase 13 family
DK878_RS10160	COG1609	Transcriptional regulator
DK878_RS10165	COG1126	abc transporter atp-binding protein
DK878_RS10170	COG0765	amino acid transport
DK878_RS10175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK878_RS10185	COG3942	CHAP domain
DK878_RS10190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DK878_RS10200	COG1447	Phosphotransferase system cellobiose-specific component IIA
DK878_RS10210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DK878_RS10210	COG3711	transcriptional antiterminator
DK878_RS10220	COG2723	6-phospho-beta-galactosidase activity
DK878_RS10225	COG1486	melibiose metabolic process
DK878_RS10235	COG3590	peptidase
DK878_RS10240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK878_RS10245	COG1321	iron dependent repressor
DK878_RS10245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DK878_RS10250	COG1121	(ABC) transporter
DK878_RS10260	COG0803	Belongs to the bacterial solute-binding protein 9 family
DK878_RS10275	COG1490	D-aminoacyl-tRNA deacylase activity
DK878_RS10285	COG0737	Belongs to the 5'-nucleotidase family
DK878_RS10305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DK878_RS10325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DK878_RS10350	COG0737	Belongs to the 5'-nucleotidase family
DK878_RS10355	COG1328	CTP reductase activity
DK878_RS10360	COG1126	abc transporter atp-binding protein
DK878_RS10370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DK878_RS10375	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DK878_RS10390	COG1438	arginine binding
DK878_RS10395	COG0018	arginyl-trna synthetase
DK878_RS10415	COG1640	4-alpha-glucanotransferase
DK878_RS10420	COG2182	Extracellular solute-binding protein
DK878_RS10425	COG1175	transmembrane transport
DK878_RS10430	COG3833	ABC-type maltose transport systems, permease component
DK878_RS10435	COG5521	maltodextrose utilization protein MalA
DK878_RS10440	COG1609	Transcriptional regulator
DK878_RS10445	COG1523	belongs to the glycosyl hydrolase 13 family
DK878_RS10450	COG1780	Probably involved in ribonucleotide reductase function
DK878_RS10455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK878_RS10460	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DK878_RS10465	COG2153	protein acetylation
DK878_RS10470	COG4989	oxidoreductase activity
DK878_RS10475	COG1216	Glycosyl transferase, family 2
DK878_RS10495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DK878_RS10505	COG0305	Participates in initiation and elongation during chromosome replication
DK878_RS10510	COG0359	binds to the 23S rRNA
DK878_RS10520	COG0445	tRNA wobble uridine modification
DK878_RS10525	COG0494	nUDIX hydrolase
DK878_RS10530	COG1733	regulation of RNA biosynthetic process
DK878_RS10540	COG0482	sulfurtransferase activity
DK878_RS10545	COG1760	l-serine dehydratase
DK878_RS10550	COG1760	l-serine dehydratase
DK878_RS10560	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DK878_RS10565	COG1122	ATPase activity
DK878_RS10570	COG1122	ATPase activity
DK878_RS10575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DK878_RS10580	COG1426	Protein conserved in bacteria
DK878_RS10585	COG0612	Peptidase, M16
DK878_RS10590	COG0612	Peptidase, M16
DK878_RS10675	COG0582	viral genome integration into host DNA
DK878_RS10685	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DK878_RS10695	COG0517	IMP dehydrogenase activity
DK878_RS10695	COG0516	GMP reductase activity
DK878_RS10705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DK878_RS10710	COG0488	(ABC) transporter
DK878_RS10740	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DK878_RS10745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DK878_RS10750	COG1475	DNA binding