locus-tag	class	description
DP112_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DP112_RS00010	COG0592	DNA-directed DNA polymerase activity
DP112_RS00030	COG0012	GTP binding
DP112_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
DP112_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DP112_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DP112_RS00065	COG0037	tRNA processing
DP112_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DP112_RS00190	COG1792	Involved in formation and maintenance of cell shape
DP112_RS00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DP112_RS00210	COG0436	Aminotransferase
DP112_RS00215	COG1381	Involved in DNA repair and RecF pathway recombination
DP112_RS00220	COG0416	fatty acid biosynthetic process
DP112_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DP112_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DP112_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DP112_RS00255	COG0138	bifunctional purine biosynthesis protein purh
DP112_RS00260	COG0151	Belongs to the GarS family
DP112_RS00265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DP112_RS00285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DP112_RS00305	COG1131	(ABC) transporter
DP112_RS00315	COG1132	(ABC) transporter
DP112_RS00330	COG2255	four-way junction helicase activity
DP112_RS00345	COG0285	dihydrofolate synthase activity
DP112_RS00360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DP112_RS00365	COG0632	four-way junction helicase activity
DP112_RS00370	COG0519	Catalyzes the synthesis of GMP from XMP
DP112_RS00385	COG1393	Belongs to the ArsC family
DP112_RS00390	COG4472	Bacterial protein of unknown function (DUF965)
DP112_RS00395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DP112_RS00400	COG3906	Belongs to the UPF0473 family
DP112_RS00410	COG0051	transcription antitermination factor activity, RNA binding
DP112_RS00415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DP112_RS00420	COG0088	Forms part of the polypeptide exit tunnel
DP112_RS00425	COG0089	rRNA binding
DP112_RS00430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DP112_RS00435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DP112_RS00440	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DP112_RS00445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DP112_RS00450	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DP112_RS00455	COG0255	Belongs to the universal ribosomal protein uL29 family
DP112_RS00460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DP112_RS00465	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DP112_RS00470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DP112_RS00475	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DP112_RS00480	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DP112_RS00490	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DP112_RS00495	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DP112_RS00500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DP112_RS00505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DP112_RS00510	COG1841	ribosomal large subunit assembly
DP112_RS00520	COG0201	protein transport
DP112_RS00525	COG0563	adenylate kinase activity
DP112_RS00530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DP112_RS00535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DP112_RS00540	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DP112_RS00550	COG0202	RNA polymerase activity
DP112_RS00660	COG0582	viral genome integration into host DNA
DP112_RS00675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DP112_RS00700	COG1674	ftsk spoiiie
DP112_RS00735	COG1121	(ABC) transporter
DP112_RS00740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP112_RS00745	COG0803	Belongs to the bacterial solute-binding protein 9 family
DP112_RS00745	COG3443	Belongs to the bacterial solute-binding protein 9 family
DP112_RS00770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP112_RS00775	COG0085	RNA polymerase activity
DP112_RS00780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DP112_RS00790	COG1619	proteins homologs of microcin C7 resistance protein MccF
DP112_RS00795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DP112_RS00800	COG1459	type II secretion system
DP112_RS00805	COG4537	Required for transformation and DNA binding
DP112_RS00835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DP112_RS00850	COG0285	dihydrofolate synthase activity
DP112_RS00860	COG1363	Peptidase, m42
DP112_RS00870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP112_RS00880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP112_RS00910	COG0459	protein refolding
DP112_RS00920	COG0049	tRNA binding
DP112_RS00925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DP112_RS00935	COG0126	phosphoglycerate kinase activity
DP112_RS00945	COG0789	Transcriptional regulator
DP112_RS00950	COG0174	glutamine synthetase
DP112_RS00965	COG1396	sequence-specific DNA binding
DP112_RS00985	COG1214	PFAM Peptidase M22, glycoprotease
DP112_RS00990	COG0456	acetyltransferase
DP112_RS00995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DP112_RS01000	COG2207	Transcriptional regulator
DP112_RS01010	COG1175	transmembrane transport
DP112_RS01015	COG0395	ABC-type sugar transport system, permease component
DP112_RS01045	COG1131	(ABC) transporter
DP112_RS01050	COG2081	HI0933 family
DP112_RS01055	COG2723	6-phospho-beta-galactosidase activity
DP112_RS01065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP112_RS01080	COG3959	Transketolase, thiamine diphosphate binding domain
DP112_RS01085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DP112_RS01090	COG0584	glycerophosphoryl diester phosphodiesterase
DP112_RS01095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DP112_RS01100	COG2222	sugar isomerase
DP112_RS01130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DP112_RS01140	COG1882	Formate acetyltransferase
DP112_RS01155	COG2910	NAD(P)H-binding
DP112_RS01170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DP112_RS01175	COG0681	Belongs to the peptidase S26 family
DP112_RS01200	COG0366	Alpha amylase catalytic
DP112_RS01205	COG1263	PTS System
DP112_RS01205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP112_RS01210	COG2188	Transcriptional regulator
DP112_RS01225	COG1193	negative regulation of DNA recombination
DP112_RS01235	COG3118	belongs to the thioredoxin family
DP112_RS01245	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DP112_RS01245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DP112_RS01270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DP112_RS01275	COG1115	amino acid carrier protein
DP112_RS01280	COG0668	transmembrane transport
DP112_RS01290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DP112_RS01300	COG0167	dihydroorotate dehydrogenase activity
DP112_RS01305	COG2843	Capsule synthesis protein
DP112_RS01310	COG0561	phosphatase activity
DP112_RS01325	COG4555	ABC transporter
DP112_RS01330	COG1309	transcriptional regulator
DP112_RS01335	COG1511	domain protein
DP112_RS01335	COG1511	domain protein
DP112_RS01360	COG1346	cytolysis
DP112_RS01365	COG2116	formate transmembrane transporter activity
DP112_RS01370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP112_RS01375	COG0433	COG0433 Predicted ATPase
DP112_RS01380	COG0494	nUDIX hydrolase
DP112_RS01395	COG1349	DNA-binding transcription factor activity
DP112_RS01405	COG0698	ribose 5-phosphate isomerase
DP112_RS01410	COG0698	ribose 5-phosphate isomerase
DP112_RS01415	COG1105	Belongs to the carbohydrate kinase PfkB family
DP112_RS01420	COG3684	Belongs to the aldolase LacD family
DP112_RS01425	COG3711	transcriptional antiterminator
DP112_RS01435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP112_RS01435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP112_RS01455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DP112_RS01460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DP112_RS01465	COG0124	histidyl-tRNA synthetase
DP112_RS01470	COG1064	alcohol dehydrogenase
DP112_RS01480	COG1012	belongs to the aldehyde dehydrogenase family
DP112_RS01480	COG1454	alcohol dehydrogenase
DP112_RS01490	COG4988	ABC transporter
DP112_RS01495	COG1132	(ABC) transporter
DP112_RS01510	COG1129	ABC transporter
DP112_RS01515	COG0534	Mate efflux family protein
DP112_RS01520	COG1132	(ABC) transporter
DP112_RS01530	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DP112_RS01550	COG3830	Belongs to the UPF0237 family
DP112_RS01555	COG2848	UPF0210 protein
DP112_RS01560	COG0588	phosphoglycerate mutase activity
DP112_RS01565	COG1420	regulation of RNA biosynthetic process
DP112_RS01570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DP112_RS01575	COG0443	Heat shock 70 kDa protein
DP112_RS01580	COG0484	heat shock protein binding
DP112_RS01595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP112_RS01600	COG0765	amino acid transport
DP112_RS01605	COG3655	Transcriptional regulator
DP112_RS01615	COG2217	Heavy metal translocating P-type atpase
DP112_RS01640	COG4475	Protein of unknown function (DUF436)
DP112_RS01645	COG1959	2 iron, 2 sulfur cluster binding
DP112_RS01685	COG0544	peptidyl-prolyl cis-trans isomerase activity
DP112_RS01690	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP112_RS01700	COG0251	oxidation-reduction process
DP112_RS01705	COG0626	cystathionine gamma-synthase activity
DP112_RS01710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DP112_RS01715	COG2964	Protein conserved in bacteria
DP112_RS01755	COG3343	RNA polymerase activity
DP112_RS01760	COG0504	CTP synthase activity
DP112_RS01770	COG0191	fructose-bisphosphate aldolase activity
DP112_RS01785	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DP112_RS01825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DP112_RS01845	COG0589	response to stress
DP112_RS01850	COG0436	Aminotransferase
DP112_RS01855	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DP112_RS01860	COG1335	isochorismatase
DP112_RS01865	COG0335	large ribosomal subunit rRNA binding
DP112_RS01875	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DP112_RS01880	COG0154	amidase activity
DP112_RS01885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DP112_RS01890	COG1609	Transcriptional regulator
DP112_RS01895	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DP112_RS01900	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DP112_RS01910	COG3142	Participates in the control of copper homeostasis
DP112_RS01925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DP112_RS01935	COG1534	Rna-binding protein
DP112_RS01940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DP112_RS01945	COG1713	HD superfamily hydrolase involved in NAD metabolism
DP112_RS01955	COG1335	isochorismatase
DP112_RS01960	COG0799	negative regulation of ribosome biogenesis
DP112_RS01970	COG2226	methyltransferase
DP112_RS01980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DP112_RS01985	COG0789	Transcriptional regulator
DP112_RS01995	COG0242	peptide deformylase activity
DP112_RS02005	COG1640	4-alpha-glucanotransferase
DP112_RS02010	COG0058	SHG alpha-glucan phosphorylase activity
DP112_RS02025	COG1263	PTS System
DP112_RS02025	COG2190	(PTS) system
DP112_RS02025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP112_RS02030	COG0217	transcriptional regulatory protein
DP112_RS02040	COG4720	Psort location CytoplasmicMembrane, score
DP112_RS02050	COG1054	Belongs to the UPF0176 family
DP112_RS02060	COG1122	ATPase activity
DP112_RS02075	COG0357	Ribosomal RNA small subunit methyltransferase G
DP112_RS02080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP112_RS02085	COG3331	DNA recombination
DP112_RS02090	COG4474	Belongs to the UPF0398 family
DP112_RS02095	COG3599	regulation of cell shape
DP112_RS02105	COG0116	Belongs to the methyltransferase superfamily
DP112_RS02115	COG1854	S-ribosylhomocysteine lyase activity
DP112_RS02120	COG1418	mRNA catabolic process
DP112_RS02130	COG1758	RNA polymerase activity
DP112_RS02135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DP112_RS02140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DP112_RS02145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP112_RS02145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP112_RS02150	COG0631	protein serine/threonine phosphatase activity
DP112_RS02155	COG0515	serine threonine protein kinase
DP112_RS02155	COG2815	serine threonine protein kinase
DP112_RS02180	COG1098	S1 RNA binding domain
DP112_RS02190	COG1739	Uncharacterized protein family UPF0029
DP112_RS02195	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DP112_RS02285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DP112_RS02290	COG2137	regulation of response to DNA damage stimulus
DP112_RS02295	COG3557	Belongs to the UPF0374 family
DP112_RS02305	COG2188	Transcriptional regulator
DP112_RS02310	COG2188	Transcriptional regulator
DP112_RS02320	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP112_RS02330	COG3716	PTS system mannose fructose sorbose family IID component
DP112_RS02345	COG2017	converts alpha-aldose to the beta-anomer
DP112_RS02360	COG0346	lactoylglutathione lyase activity
DP112_RS02385	COG3852	Histidine kinase
DP112_RS02405	COG0326	Molecular chaperone. Has ATPase activity
DP112_RS02435	COG1217	gtp-binding protein TYPA
DP112_RS02450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DP112_RS02470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DP112_RS02475	COG1799	cell septum assembly
DP112_RS02490	COG3599	regulation of cell shape
DP112_RS02510	COG0406	alpha-ribazole phosphatase activity
DP112_RS02510	COG0494	nUDIX hydrolase
DP112_RS02515	COG0542	response to heat
DP112_RS02520	COG4703	Protein of unknown function (DUF1797)
DP112_RS02525	COG0765	amino acid transport
DP112_RS02535	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DP112_RS02560	COG3590	peptidase
DP112_RS02575	COG0745	RESPONSE REGULATOR receiver
DP112_RS02580	COG3850	Histidine kinase
DP112_RS02580	COG5002	protein histidine kinase activity
DP112_RS02585	COG1755	Isoprenylcysteine carboxyl methyltransferase
DP112_RS02595	COG1755	Isoprenylcysteine carboxyl methyltransferase
DP112_RS02605	COG2321	neutral zinc metallopeptidase
DP112_RS02610	COG1570	exodeoxyribonuclease VII activity
DP112_RS02615	COG1722	exodeoxyribonuclease VII activity
DP112_RS02625	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DP112_RS02630	COG1438	arginine binding
DP112_RS02635	COG0497	DNA recombination
DP112_RS02640	COG1307	EDD domain protein, DegV family
DP112_RS02645	COG2755	lipolytic protein G-D-S-L family
DP112_RS02655	COG0776	regulation of translation
DP112_RS02680	COG3425	synthase
DP112_RS02685	COG0183	Belongs to the thiolase family
DP112_RS02700	COG0726	polysaccharide deacetylase
DP112_RS02705	COG0513	Belongs to the DEAD box helicase family
DP112_RS02710	COG0673	inositol 2-dehydrogenase activity
DP112_RS02720	COG1695	Transcriptional regulator
DP112_RS02730	COG1956	GAF domain-containing protein
DP112_RS02750	COG1363	Peptidase, m42
DP112_RS02760	COG2131	deaminase
DP112_RS02765	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DP112_RS02770	COG2249	NAD(P)H dehydrogenase (quinone) activity
DP112_RS02775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DP112_RS02785	COG0024	Methionine aminopeptidase
DP112_RS02795	COG2246	polysaccharide biosynthetic process
DP112_RS02800	COG4708	membrane
DP112_RS02805	COG0656	L-ascorbic acid biosynthetic process
DP112_RS02830	COG3091	SprT-like family
DP112_RS02850	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DP112_RS02855	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DP112_RS02870	COG1733	regulation of RNA biosynthetic process
DP112_RS02895	COG1125	glycine betaine transport
DP112_RS02895	COG0517	IMP dehydrogenase activity
DP112_RS02900	COG1174	glycine betaine transport
DP112_RS02910	COG0436	Aminotransferase
DP112_RS02925	COG2205	protein histidine kinase activity
DP112_RS02930	COG1136	(ABC) transporter
DP112_RS02935	COG0577	efflux transmembrane transporter activity
DP112_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
DP112_RS02995	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DP112_RS03000	COG0494	nUDIX hydrolase
DP112_RS03040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DP112_RS03060	COG1609	Transcriptional regulator
DP112_RS03065	COG4209	transmembrane transport
DP112_RS03070	COG0395	ABC-type sugar transport system, permease component
DP112_RS03075	COG1653	transport
DP112_RS03085	COG0697	spore germination
DP112_RS03085	COG1674	ftsk spoiiie
DP112_RS03090	COG0346	lactoylglutathione lyase activity
DP112_RS03115	COG0625	glutathione transferase activity
DP112_RS03125	COG2244	polysaccharide biosynthetic process
DP112_RS03130	COG0528	UMP kinase activity
DP112_RS03140	COG0233	cytoplasmic translational termination
DP112_RS03145	COG2996	Protein conserved in bacteria
DP112_RS03160	COG4479	Belongs to the UPF0346 family
DP112_RS03165	COG1702	phosphate starvation-inducible protein PhoH
DP112_RS03185	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DP112_RS03190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DP112_RS03195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DP112_RS03210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP112_RS03215	COG3022	response to hydroperoxide
DP112_RS03220	COG1316	TRANSCRIPTIONal
DP112_RS03225	COG3944	biosynthesis protein
DP112_RS03235	COG4464	protein tyrosine phosphatase activity
DP112_RS03245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DP112_RS03250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DP112_RS03275	COG1216	Glycosyl transferase, family 2
DP112_RS03275	COG0463	Glycosyl transferase, family 2
DP112_RS03290	COG0562	UDP-galactopyranose mutase
DP112_RS03305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DP112_RS03320	COG0436	Aminotransferase
DP112_RS03340	COG0534	Mate efflux family protein
DP112_RS03345	COG0251	oxidation-reduction process
DP112_RS03350	COG1660	Displays ATPase and GTPase activities
DP112_RS03355	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DP112_RS03360	COG1481	regulation of sporulation
DP112_RS03375	COG0454	-acetyltransferase
DP112_RS03380	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP112_RS03385	COG0549	Belongs to the carbamate kinase family
DP112_RS03390	COG1288	antiporter activity
DP112_RS03395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DP112_RS03400	COG3583	domain protein
DP112_RS03400	COG3064	Membrane
DP112_RS03400	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DP112_RS03410	COG0443	Heat shock 70 kDa protein
DP112_RS03425	COG1438	arginine binding
DP112_RS03430	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DP112_RS03435	COG0363	glucosamine-6-phosphate deaminase activity
DP112_RS03445	COG0435	Glutathione S-transferase
DP112_RS03450	COG1187	pseudouridine synthase activity
DP112_RS03455	COG0386	Belongs to the glutathione peroxidase family
DP112_RS03460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP112_RS03465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP112_RS03470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DP112_RS03475	COG1120	ATPase activity
DP112_RS03480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DP112_RS03485	COG0204	Acyl-transferase
DP112_RS03490	COG1555	photosystem II stabilization
DP112_RS03490	COG1596	polysaccharide export
DP112_RS03495	COG0658	competence protein
DP112_RS03495	COG2333	competence protein COMEC
DP112_RS03505	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DP112_RS03505	COG3583	domain protein
DP112_RS03510	COG1466	dna polymerase III delta subunit
DP112_RS03515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DP112_RS03520	COG0737	Belongs to the 5'-nucleotidase family
DP112_RS03535	COG0038	chloride channel
DP112_RS03540	COG1605	Chorismate mutase
DP112_RS03540	COG0287	Prephenate dehydrogenase
DP112_RS03550	COG0716	FMN binding
DP112_RS03555	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DP112_RS03570	COG0772	Belongs to the SEDS family
DP112_RS03575	COG0693	protein deglycase activity
DP112_RS03580	COG0187	DNA topoisomerase II activity
DP112_RS03585	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DP112_RS03590	COG0560	Phosphoserine phosphatase
DP112_RS03625	COG1011	Hydrolase
DP112_RS03635	COG2706	6-phosphogluconolactonase activity
DP112_RS03650	COG3527	Alpha-acetolactate decarboxylase
DP112_RS03660	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DP112_RS03675	COG3842	ATPase activity
DP112_RS03710	COG0488	(ABC) transporter
DP112_RS03720	COG2226	methyltransferase
DP112_RS03725	COG3442	glutamine amidotransferase
DP112_RS03730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DP112_RS03745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DP112_RS03750	COG0488	(ABC) transporter
DP112_RS03755	COG2226	methyltransferase
DP112_RS03780	COG1573	uracil-dna glycosylase
DP112_RS03790	COG1704	LemA family
DP112_RS03795	COG2268	Band 7 protein
DP112_RS03810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DP112_RS03825	COG0732	type I restriction modification DNA specificity domain
DP112_RS03835	COG4974	Belongs to the 'phage' integrase family
DP112_RS03845	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DP112_RS03850	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DP112_RS03855	COG1393	Belongs to the ArsC family
DP112_RS03860	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DP112_RS03865	COG0813	purine-nucleoside phosphorylase activity
DP112_RS03870	COG0058	SHG alpha-glucan phosphorylase activity
DP112_RS03880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP112_RS03890	COG1051	belongs to the nudix hydrolase family
DP112_RS03895	COG0647	UMP catabolic process
DP112_RS03905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DP112_RS03910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DP112_RS03915	COG1970	mechanosensitive ion channel activity
DP112_RS03920	COG0358	DNA primase activity
DP112_RS03925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DP112_RS03930	COG2151	metal-sulfur cluster biosynthetic enzyme
DP112_RS03935	COG1982	Orn Lys Arg decarboxylase major
DP112_RS03940	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DP112_RS03980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DP112_RS03990	COG1131	(ABC) transporter
DP112_RS03995	COG2188	Transcriptional regulator
DP112_RS04005	COG0205	6-phosphofructokinase activity
DP112_RS04010	COG0469	pyruvate kinase activity
DP112_RS04045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DP112_RS04050	COG0657	acetylesterase activity
DP112_RS04050	COG2755	lipolytic protein G-D-S-L family
DP112_RS04060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DP112_RS04065	COG0765	amino acid transport
DP112_RS04070	COG1126	abc transporter atp-binding protein
DP112_RS04075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP112_RS04085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DP112_RS04100	COG1846	Transcriptional regulator
DP112_RS04105	COG3759	membrane
DP112_RS04140	COG2195	Cleaves the N-terminal amino acid of tripeptides
DP112_RS04145	COG0561	phosphatase activity
DP112_RS04185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DP112_RS04190	COG0196	riboflavin kinase activity
DP112_RS04195	COG1393	Belongs to the ArsC family
DP112_RS04200	COG4476	Belongs to the UPF0223 family
DP112_RS04205	COG0483	inositol monophosphate 1-phosphatase activity
DP112_RS04210	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DP112_RS04210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP112_RS04220	COG0573	inorganic phosphate transmembrane transporter activity
DP112_RS04225	COG0581	inorganic phosphate transmembrane transporter activity
DP112_RS04230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DP112_RS04235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DP112_RS04240	COG0704	Plays a role in the regulation of phosphate uptake
DP112_RS04250	COG0745	RESPONSE REGULATOR receiver
DP112_RS04255	COG5002	protein histidine kinase activity
DP112_RS04270	COG1072	(Pantothenic acid kinase))
DP112_RS04275	COG2813	Specifically methylates the guanine in position
DP112_RS04280	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DP112_RS04290	COG0295	cytidine deaminase activity
DP112_RS04295	COG1744	ABC transporter substrate-binding protein PnrA-like
DP112_RS04300	COG3845	ABC transporter
DP112_RS04305	COG4603	Belongs to the binding-protein-dependent transport system permease family
DP112_RS04310	COG1079	Belongs to the binding-protein-dependent transport system permease family
DP112_RS04320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DP112_RS04325	COG0039	L-malate dehydrogenase activity
DP112_RS04330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DP112_RS04350	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DP112_RS04385	COG4116	CYTH
DP112_RS04390	COG2357	RelA SpoT domain protein
DP112_RS04395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DP112_RS04400	COG0564	pseudouridine synthase activity
DP112_RS04405	COG0280	phosphate acetyltransferase
DP112_RS04410	COG1132	(ABC) transporter
DP112_RS04415	COG1132	(ABC) transporter
DP112_RS04425	COG1194	a g-specific adenine glycosylase
DP112_RS04430	COG1396	sequence-specific DNA binding
DP112_RS04450	COG2873	o-acetylhomoserine
DP112_RS04455	COG0488	(ABC) transporter
DP112_RS04465	COG1126	abc transporter atp-binding protein
DP112_RS04490	COG3583	domain protein
DP112_RS04505	COG0789	Transcriptional regulator
DP112_RS04505	COG4978	Transcriptional regulator
DP112_RS04525	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DP112_RS04530	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
DP112_RS04535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DP112_RS04540	COG1882	Formate acetyltransferase
DP112_RS04545	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DP112_RS04575	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
DP112_RS04580	COG4766	ethanolamine catabolic process
DP112_RS04590	COG1454	alcohol dehydrogenase
DP112_RS04590	COG1012	belongs to the aldehyde dehydrogenase family
DP112_RS04595	COG4869	propanediol catabolic process
DP112_RS04620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP112_RS04625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP112_RS04635	COG0297	glycogen (starch) synthase activity
DP112_RS04645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DP112_RS04650	COG0583	DNA-binding transcription factor activity
DP112_RS04655	COG0543	2 iron, 2 sulfur cluster binding
DP112_RS04660	COG0167	dihydroorotate dehydrogenase activity
DP112_RS04665	COG0284	orotidine-5'-phosphate decarboxylase activity
DP112_RS04670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DP112_RS04680	COG0463	Glycosyl transferase, family 2
DP112_RS04685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DP112_RS04695	COG0737	Belongs to the 5'-nucleotidase family
DP112_RS04700	COG0424	maF-like protein
DP112_RS04710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DP112_RS04715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DP112_RS04725	COG1272	protein, Hemolysin III
DP112_RS04740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DP112_RS04740	COG0425	Belongs to the sulfur carrier protein TusA family
DP112_RS04745	COG0110	maltose O-acetyltransferase activity
DP112_RS04750	COG0758	DNA mediated transformation
DP112_RS04755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DP112_RS04760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DP112_RS04765	COG0222	ribosome binding
DP112_RS04770	COG0647	UMP catabolic process
DP112_RS04775	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DP112_RS04815	COG1136	(ABC) transporter
DP112_RS04835	COG0745	RESPONSE REGULATOR receiver
DP112_RS04855	COG4974	Belongs to the 'phage' integrase family
DP112_RS04880	COG1660	Displays ATPase and GTPase activities
DP112_RS04895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DP112_RS04900	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DP112_RS04905	COG2188	Transcriptional regulator
DP112_RS04915	COG4268	DNA restriction-modification system
DP112_RS04920	COG1401	restriction endodeoxyribonuclease activity
DP112_RS04945	COG4221	oxidoreductase activity
DP112_RS04960	COG0741	lytic transglycosylase activity
DP112_RS04970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DP112_RS04980	COG0009	L-threonylcarbamoyladenylate synthase
DP112_RS04985	COG2890	protein-(glutamine-N5) methyltransferase activity
DP112_RS04990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DP112_RS05015	COG0481	GTPase activity
DP112_RS05030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DP112_RS05040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DP112_RS05045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DP112_RS05060	COG1940	carbohydrate kinase activity
DP112_RS05070	COG0488	(ABC) transporter
DP112_RS05075	COG0617	tRNA 3'-terminal CCA addition
DP112_RS05085	COG1307	EDD domain protein, DegV family
DP112_RS05095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DP112_RS05095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DP112_RS05095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP112_RS05100	COG1105	Belongs to the carbohydrate kinase PfkB family
DP112_RS05105	COG1349	DNA-binding transcription factor activity
DP112_RS05110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DP112_RS05115	COG0336	Belongs to the RNA methyltransferase TrmD family
DP112_RS05120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DP112_RS05125	COG0534	Mate efflux family protein
DP112_RS05135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DP112_RS05140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DP112_RS05155	COG1177	transmembrane transport
DP112_RS05160	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP112_RS05165	COG3842	ATPase activity
DP112_RS05170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DP112_RS05175	COG0083	homoserine kinase activity
DP112_RS05180	COG0460	homoserine dehydrogenase
DP112_RS05185	COG0726	polysaccharide deacetylase
DP112_RS05190	COG1132	(ABC) transporter
DP112_RS05205	COG0228	four-way junction DNA binding
DP112_RS05215	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DP112_RS05220	COG2521	methyltransferase
DP112_RS05220	COG2136	Putative SAM-dependent methyltransferase
DP112_RS05230	COG0505	Belongs to the CarA family
DP112_RS05235	COG0540	Belongs to the ATCase OTCase family
DP112_RS05240	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DP112_RS05250	COG2824	Alkylphosphonate utilization operon protein PhnA
DP112_RS05255	COG0564	pseudouridine synthase activity
DP112_RS05275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DP112_RS05280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DP112_RS05290	COG1114	Component of the transport system for branched-chain amino acids
DP112_RS05295	COG0301	tRNA thio-modification
DP112_RS05300	COG1442	glycosyl transferase family 8
DP112_RS05305	COG1104	cysteine desulfurase activity
DP112_RS05330	COG0539	negative regulation of cytoplasmic translation
DP112_RS05350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DP112_RS05360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DP112_RS05375	COG2184	nucleotidyltransferase activity
DP112_RS05380	COG0187	DNA topoisomerase II activity
DP112_RS05390	COG1074	ATP-dependent DNA helicase activity
DP112_RS05395	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DP112_RS05430	COG1131	(ABC) transporter
DP112_RS05465	COG1011	Hydrolase
DP112_RS05475	COG0210	DNA helicase
DP112_RS05490	COG1164	Oligoendopeptidase f
DP112_RS05500	COG0346	lactoylglutathione lyase activity
DP112_RS05505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP112_RS05510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DP112_RS05515	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DP112_RS05525	COG0446	pyridine nucleotide-disulphide oxidoreductase
DP112_RS05530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP112_RS05535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DP112_RS05555	COG1882	Formate acetyltransferase
DP112_RS05560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP112_RS05565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP112_RS05570	COG1447	Phosphotransferase system cellobiose-specific component IIA
DP112_RS05580	COG1349	DNA-binding transcription factor activity
DP112_RS05585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DP112_RS05615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP112_RS05625	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DP112_RS05635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DP112_RS05640	COG4684	Psort location CytoplasmicMembrane, score
DP112_RS05645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DP112_RS05655	COG2132	Multicopper oxidase
DP112_RS05665	COG2217	Heavy metal translocating P-type atpase
DP112_RS05670	COG2217	Heavy metal translocating P-type atpase
DP112_RS05715	COG0860	N-Acetylmuramoyl-L-alanine amidase
DP112_RS05715	COG1388	LysM domain
DP112_RS05785	COG0740	serine-type endopeptidase activity
DP112_RS05790	COG4695	Portal protein
DP112_RS05835	COG0270	DNA (cytosine-5-)-methyltransferase activity
DP112_RS05855	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DP112_RS05905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DP112_RS05905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DP112_RS05940	COG0456	acetyltransferase
DP112_RS06020	COG1388	LysM domain
DP112_RS06020	COG0860	N-Acetylmuramoyl-L-alanine amidase
DP112_RS06090	COG0740	serine-type endopeptidase activity
DP112_RS06095	COG4695	Portal protein
DP112_RS06140	COG0270	DNA (cytosine-5-)-methyltransferase activity
DP112_RS06165	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DP112_RS06210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DP112_RS06210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DP112_RS06235	COG3620	sequence-specific DNA binding
DP112_RS06255	COG0488	(ABC) transporter
DP112_RS06285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DP112_RS06295	COG0077	Prephenate dehydratase
DP112_RS06300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DP112_RS06310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DP112_RS06315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DP112_RS06320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DP112_RS06325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DP112_RS06335	COG1116	anion transmembrane transporter activity
DP112_RS06335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DP112_RS06340	COG4120	Belongs to the binding-protein-dependent transport system permease family
DP112_RS06355	COG3684	Belongs to the aldolase LacD family
DP112_RS06365	COG3679	Belongs to the UPF0342 family
DP112_RS06370	COG0287	Prephenate dehydrogenase
DP112_RS06375	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DP112_RS06380	COG0710	3-dehydroquinate dehydratase activity
DP112_RS06385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DP112_RS06390	COG1368	sulfuric ester hydrolase activity
DP112_RS06405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DP112_RS06415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DP112_RS06465	COG1216	Glycosyl transferase, family 2
DP112_RS06465	COG1442	glycosyl transferase family 8
DP112_RS06470	COG1442	glycosyl transferase family 8
DP112_RS06500	COG1216	Glycosyl transferase, family 2
DP112_RS06500	COG1442	glycosyl transferase family 8
DP112_RS06530	COG1091	dTDP-4-dehydrorhamnose reductase activity
DP112_RS06535	COG1088	dTDP-glucose 4,6-dehydratase activity
DP112_RS06540	COG0135	phosphoribosylanthranilate isomerase activity
DP112_RS06550	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DP112_RS06560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DP112_RS06565	COG2384	SAM-dependent methyltransferase
DP112_RS06580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DP112_RS06590	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DP112_RS06590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DP112_RS06595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DP112_RS06605	COG0300	oxidoreductase activity
DP112_RS06610	COG1234	tRNA 3'-trailer cleavage
DP112_RS06620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DP112_RS06625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DP112_RS06635	COG2807	transmembrane transport
DP112_RS06640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DP112_RS06645	COG2610	gluconate transmembrane transporter activity
DP112_RS06665	COG0302	gtp cyclohydrolase
DP112_RS06670	COG1051	belongs to the nudix hydrolase family
DP112_RS06695	COG0072	phenylalanine-tRNA ligase activity
DP112_RS06695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP112_RS06720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DP112_RS06730	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DP112_RS06735	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DP112_RS06740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DP112_RS06745	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DP112_RS06750	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DP112_RS06755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DP112_RS06760	COG0356	it plays a direct role in the translocation of protons across the membrane
DP112_RS06770	COG1597	lipid kinase activity
DP112_RS06780	COG0701	Predicted permease
DP112_RS06785	COG3689	TIGRFAM TIGR03943 family protein
DP112_RS06790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DP112_RS06820	COG0552	protein localization to endoplasmic reticulum
DP112_RS06825	COG0561	phosphatase activity
DP112_RS06830	COG0561	phosphatase activity
DP112_RS06835	COG1196	nuclear chromosome segregation
DP112_RS06870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP112_RS06875	COG0538	isocitrate dehydrogenase activity
DP112_RS06880	COG0372	Belongs to the citrate synthase family
DP112_RS06885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DP112_RS06890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DP112_RS06895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DP112_RS06900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DP112_RS06935	COG1476	TRANSCRIPTIONal
DP112_RS06950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DP112_RS06960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DP112_RS06965	COG4122	O-methyltransferase activity
DP112_RS06990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP112_RS06990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP112_RS07020	COG0531	amino acid
DP112_RS07030	COG0708	Exodeoxyribonuclease III
DP112_RS07040	COG1393	Belongs to the ArsC family
DP112_RS07045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DP112_RS07050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DP112_RS07060	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DP112_RS07070	COG4467	Involved in initiation control of chromosome replication
DP112_RS07075	COG0470	DNA polymerase III
DP112_RS07080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DP112_RS07085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP112_RS07100	COG0517	IMP dehydrogenase activity
DP112_RS07135	COG0683	leucine binding
DP112_RS07155	COG1674	ftsk spoiiie
DP112_RS07165	COG2946	Replication initiation factor
DP112_RS07195	COG0741	lytic transglycosylase activity
DP112_RS07195	COG0791	NLP P60 protein
DP112_RS07265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DP112_RS07270	COG0366	Alpha amylase catalytic
DP112_RS07275	COG0366	Alpha amylase catalytic
DP112_RS07280	COG0395	ABC-type sugar transport system, permease component
DP112_RS07285	COG1175	transmembrane transport
DP112_RS07290	COG1653	transport
DP112_RS07300	COG2207	Transcriptional regulator
DP112_RS07305	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DP112_RS07310	COG0626	cystathionine gamma-synthase activity
DP112_RS07330	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DP112_RS07335	COG2827	Endonuclease containing a URI domain
DP112_RS07355	COG0640	Transcriptional regulator
DP112_RS07360	COG0513	Belongs to the DEAD box helicase family
DP112_RS07370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP112_RS07400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DP112_RS07410	COG2249	NAD(P)H dehydrogenase (quinone) activity
DP112_RS07420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DP112_RS07445	COG1181	Belongs to the D-alanine--D-alanine ligase family
DP112_RS07450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DP112_RS07455	COG0768	penicillin binding
DP112_RS07460	COG0488	(ABC) transporter
DP112_RS07465	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DP112_RS07475	COG0745	RESPONSE REGULATOR receiver
DP112_RS07480	COG1126	abc transporter atp-binding protein
DP112_RS07485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP112_RS07490	COG0765	amino acid transport
DP112_RS07495	COG0765	amino acid transport
DP112_RS07510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DP112_RS07525	COG0438	transferase activity, transferring glycosyl groups
DP112_RS07540	COG5002	protein histidine kinase activity
DP112_RS07550	COG1609	Transcriptional regulator
DP112_RS07570	COG0343	queuine tRNA-ribosyltransferase activity
DP112_RS07580	COG1832	CoA-binding protein
DP112_RS07605	COG1136	(ABC) transporter
DP112_RS07620	COG1131	(ABC) transporter
DP112_RS07650	COG0789	Transcriptional regulator
DP112_RS07655	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DP112_RS07660	COG2217	Heavy metal translocating P-type atpase
DP112_RS07675	COG1063	alcohol dehydrogenase
DP112_RS07700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DP112_RS07705	COG0557	exoribonuclease II activity
DP112_RS07715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DP112_RS07720	COG2814	Major facilitator Superfamily
DP112_RS07730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DP112_RS07735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DP112_RS07740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DP112_RS07750	COG1737	Transcriptional regulator
DP112_RS07770	COG1011	Hydrolase
DP112_RS07775	COG1132	(ABC) transporter
DP112_RS07780	COG1132	(ABC) transporter
DP112_RS07810	COG2177	Part of the ABC transporter FtsEX involved in
DP112_RS07815	COG2884	Cell division ATP-binding protein ftsE
DP112_RS07825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DP112_RS07860	COG1078	dGTPase activity
DP112_RS07870	COG0149	triose-phosphate isomerase activity
DP112_RS07875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DP112_RS07890	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DP112_RS07895	COG0772	Belongs to the SEDS family
DP112_RS07925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DP112_RS07935	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DP112_RS07950	COG0577	efflux transmembrane transporter activity
DP112_RS07955	COG1136	(ABC) transporter
DP112_RS07960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP112_RS07965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP112_RS07970	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DP112_RS07975	COG1268	BioY protein
DP112_RS07980	COG4443	Transcriptional Coactivator p15 (PC4)
DP112_RS07990	COG0826	peptidase U32
DP112_RS08005	COG0789	Transcriptional regulator
DP112_RS08015	COG1227	inorganic diphosphatase activity
DP112_RS08025	COG1733	regulation of RNA biosynthetic process
DP112_RS08030	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DP112_RS08035	COG2514	catechol 2,3-dioxygenase activity
DP112_RS08045	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DP112_RS08050	COG1253	flavin adenine dinucleotide binding
DP112_RS08055	COG1119	ATPase activity
DP112_RS08070	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DP112_RS08090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DP112_RS08095	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DP112_RS08100	COG0133	tryptophan synthase activity
DP112_RS08115	COG4470	Protein conserved in bacteria
DP112_RS08120	COG3480	Lon protease (S16) C-terminal proteolytic domain
DP112_RS08125	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DP112_RS08130	COG0742	ribosomal rna small subunit methyltransferase
DP112_RS08140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DP112_RS08145	COG4483	Protein conserved in bacteria
DP112_RS08150	COG2197	response regulator
DP112_RS08155	COG4585	Histidine kinase
DP112_RS08160	COG0842	Transport permease protein
DP112_RS08165	COG1131	(ABC) transporter
DP112_RS08180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP112_RS08195	COG0671	phosphoesterase, PA-phosphatase related
DP112_RS08200	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DP112_RS08215	COG0747	negative chemotaxis
DP112_RS08220	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DP112_RS08225	COG1187	pseudouridine synthase activity
DP112_RS08230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DP112_RS08235	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DP112_RS08240	COG0582	viral genome integration into host DNA
DP112_RS08260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DP112_RS08265	COG3763	UPF0154 protein
DP112_RS08275	COG3579	cysteine-type endopeptidase activity
DP112_RS08290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP112_RS08295	COG1254	Belongs to the acylphosphatase family
DP112_RS08305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DP112_RS08320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DP112_RS08330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DP112_RS08345	COG1160	GTP binding
DP112_RS08355	COG1484	DNA-dependent DNA replication
DP112_RS08365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DP112_RS08370	COG0628	permease
DP112_RS08375	COG0745	RESPONSE REGULATOR receiver
DP112_RS08380	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DP112_RS08390	COG0492	ferredoxin-NADP+ reductase activity
DP112_RS08400	COG0513	Belongs to the DEAD box helicase family
DP112_RS08405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DP112_RS08410	COG0768	penicillin binding
DP112_RS08420	COG0275	rRNA processing
DP112_RS08465	COG4939	FMN-binding domain protein
DP112_RS08470	COG0142	geranyltranstransferase activity
DP112_RS08475	COG1252	NADH dehydrogenase
DP112_RS08490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DP112_RS08495	COG0569	domain protein
DP112_RS08500	COG0534	Mate efflux family protein
DP112_RS08515	COG0751	glycine-tRNA ligase activity
DP112_RS08540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DP112_RS08550	COG1464	Belongs to the NlpA lipoprotein family
DP112_RS08555	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP112_RS08560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DP112_RS08570	COG2252	PERMEase
DP112_RS08575	COG0561	phosphatase activity
DP112_RS08585	COG3715	PTS system
DP112_RS08590	COG3716	PTS system mannose fructose sorbose family IID component
DP112_RS08605	COG1983	PspC domain protein
DP112_RS08610	COG1266	CAAX protease self-immunity
DP112_RS08630	COG0825	malonyl-CoA metabolic process
DP112_RS08640	COG0439	Biotin carboxylase
DP112_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
DP112_RS08665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DP112_RS08670	COG2070	2-Nitropropane dioxygenase
DP112_RS08680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DP112_RS08690	COG1024	Enoyl-CoA hydratase
DP112_RS08695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP112_RS08700	COG0527	aspartate kinase activity
DP112_RS08705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DP112_RS08710	COG0736	holo-[acyl-carrier-protein] synthase activity
DP112_RS08715	COG0653	protein targeting
DP112_RS08720	COG3583	domain protein
DP112_RS08720	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DP112_RS08725	COG1940	carbohydrate kinase activity
DP112_RS08730	COG1263	PTS System
DP112_RS08730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP112_RS08730	COG2190	(PTS) system
DP112_RS08735	COG1621	beta-fructofuranosidase activity
DP112_RS08740	COG1609	Transcriptional regulator
DP112_RS08745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP112_RS08760	COG0006	proline dipeptidase activity
DP112_RS08765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DP112_RS08780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DP112_RS08785	COG0629	single-stranded DNA binding
DP112_RS08795	COG0095	Lipoate-protein ligase
DP112_RS08805	COG2723	6-phospho-beta-galactosidase activity
DP112_RS08820	COG2723	6-phospho-beta-galactosidase activity
DP112_RS08825	COG0346	lactoylglutathione lyase activity
DP112_RS08830	COG2723	6-phospho-beta-galactosidase activity
DP112_RS08835	COG2207	Transcriptional regulator
DP112_RS08845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP112_RS08845	COG2190	(PTS) system
DP112_RS08845	COG1263	PTS System
DP112_RS08850	COG3711	transcriptional antiterminator
DP112_RS08855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP112_RS08865	COG1447	Phosphotransferase system cellobiose-specific component IIA
DP112_RS08870	COG3711	transcriptional antiterminator
DP112_RS08870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP112_RS08890	COG2723	6-phospho-beta-galactosidase activity
DP112_RS08905	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP112_RS08910	COG0022	dehydrogenase e1 component
DP112_RS08910	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP112_RS08915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DP112_RS08935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DP112_RS08940	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DP112_RS08950	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DP112_RS08955	COG0195	Participates in both transcription termination and antitermination
DP112_RS08965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DP112_RS08975	COG4473	ABC transporter
DP112_RS08980	COG1131	(ABC) transporter
DP112_RS08985	COG0537	adenosine 5'-monophosphoramidase activity
DP112_RS08995	COG1316	TRANSCRIPTIONal
DP112_RS09005	COG0802	atpase or kinase
DP112_RS09010	COG1461	Dihydroxyacetone kinase
DP112_RS09020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DP112_RS09025	COG0601	transmembrane transport
DP112_RS09030	COG4608	Belongs to the ABC transporter superfamily
DP112_RS09045	COG1686	Belongs to the peptidase S11 family
DP112_RS09060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DP112_RS09065	COG0719	Fe-S assembly protein
DP112_RS09075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DP112_RS09080	COG4862	establishment of competence for transformation
DP112_RS09085	COG1968	undecaprenyl-diphosphatase activity
DP112_RS09090	COG0765	amino acid transport
DP112_RS09110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DP112_RS09115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DP112_RS09120	COG0440	acetolactate synthase activity
DP112_RS09130	COG0463	Glycosyl transferase, family 2
DP112_RS09145	COG0129	dihydroxy-acid dehydratase activity
DP112_RS09155	COG2151	metal-sulfur cluster biosynthetic enzyme
DP112_RS09205	COG1216	Glycosyl transferase, family 2
DP112_RS09205	COG1442	glycosyl transferase family 8
DP112_RS09220	COG1442	glycosyl transferase family 8
DP112_RS09220	COG1216	Glycosyl transferase, family 2
DP112_RS09230	COG1442	glycosyl transferase family 8
DP112_RS09245	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DP112_RS09265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP112_RS09290	COG3842	ATPase activity
DP112_RS09300	COG4753	response regulator
DP112_RS09300	COG2207	Transcriptional regulator
DP112_RS09310	COG1653	transport
DP112_RS09315	COG0395	ABC-type sugar transport system, permease component
DP112_RS09320	COG1175	transmembrane transport
DP112_RS09335	COG0383	alpha-mannosidase activity
DP112_RS09355	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DP112_RS09370	COG1045	serine acetyltransferase
DP112_RS09375	COG1185	polyribonucleotide nucleotidyltransferase activity
DP112_RS09385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DP112_RS09415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DP112_RS09420	COG1187	pseudouridine synthase activity
DP112_RS09440	COG0242	peptide deformylase activity
DP112_RS09470	COG0066	3-isopropylmalate dehydratase activity
DP112_RS09495	COG2309	aminopeptidase activity
DP112_RS09505	COG2176	DNA-directed DNA polymerase activity
DP112_RS09530	COG2376	Dihydroxyacetone kinase
DP112_RS09540	COG2376	Dihydroxyacetone kinase
DP112_RS09545	COG1461	Dihydroxyacetone kinase
DP112_RS09550	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DP112_RS09555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP112_RS09560	COG0442	prolyl-tRNA aminoacylation
DP112_RS09570	COG4589	Belongs to the CDS family
DP112_RS09575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DP112_RS09580	COG1862	Preprotein translocase
DP112_RS09590	COG2918	glutathione biosynthetic process
DP112_RS09590	COG1181	Belongs to the D-alanine--D-alanine ligase family
DP112_RS09600	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DP112_RS09605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DP112_RS09610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DP112_RS09620	COG0454	-acetyltransferase
DP112_RS09625	COG0542	response to heat
DP112_RS09630	COG4463	regulation of RNA biosynthetic process
DP112_RS09650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DP112_RS09785	COG0582	viral genome integration into host DNA
DP112_RS09850	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DP112_RS09935	COG0582	viral genome integration into host DNA
DP112_RS09955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DP112_RS09960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP112_RS09965	COG0492	ferredoxin-NADP+ reductase activity
DP112_RS09970	COG0564	pseudouridine synthase activity
DP112_RS09975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DP112_RS09995	COG1564	THIamine pyrophosphokinase
DP112_RS10005	COG1162	GTPase activity
DP112_RS10020	COG4988	ABC transporter
DP112_RS10025	COG1132	(ABC) transporter
DP112_RS10045	COG2333	competence protein COMEC
DP112_RS10045	COG0658	competence protein
DP112_RS10045	COG0658	competence protein
DP112_RS10045	COG2333	competence protein COMEC
DP112_RS10070	COG0084	hydrolase, TatD family'
DP112_RS10080	COG1847	R3H domain protein
DP112_RS10090	COG0594	ribonuclease P activity
DP112_RS10095	COG0165	Argininosuccinate lyase
DP112_RS10100	COG0137	argininosuccinate synthase activity
DP112_RS10110	COG1827	regulation of RNA biosynthetic process
DP112_RS10125	COG2040	homocysteine
DP112_RS10130	COG0833	amino acid
DP112_RS10160	COG1442	glycosyl transferase family 8
DP112_RS10185	COG0756	dUTP diphosphatase activity
DP112_RS10200	COG2832	Protein of unknown function (DUF454)
DP112_RS10220	COG1132	(ABC) transporter
DP112_RS10225	COG1132	(ABC) transporter
DP112_RS10235	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DP112_RS10240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DP112_RS10245	COG0705	Rhomboid family
DP112_RS10250	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DP112_RS10255	COG1473	amidohydrolase
DP112_RS10260	COG2171	N-acyltransferase activity
DP112_RS10270	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DP112_RS10280	COG3732	PTS system glucitol sorbitol-specific
DP112_RS10285	COG3730	PTS system glucitol sorbitol-specific
DP112_RS10310	COG1442	glycosyl transferase family 8
DP112_RS10330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DP112_RS10355	COG3623	hexulose-6-phosphate isomerase
DP112_RS10385	COG1523	belongs to the glycosyl hydrolase 13 family
DP112_RS10390	COG1609	Transcriptional regulator
DP112_RS10395	COG1126	abc transporter atp-binding protein
DP112_RS10400	COG0765	amino acid transport
DP112_RS10405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP112_RS10410	COG3942	CHAP domain
DP112_RS10415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP112_RS10425	COG1447	Phosphotransferase system cellobiose-specific component IIA
DP112_RS10435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP112_RS10435	COG3711	transcriptional antiterminator
DP112_RS10445	COG2723	6-phospho-beta-galactosidase activity
DP112_RS10450	COG1486	melibiose metabolic process
DP112_RS10460	COG3590	peptidase
DP112_RS10465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP112_RS10470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP112_RS10470	COG1321	iron dependent repressor
DP112_RS10475	COG1121	(ABC) transporter
DP112_RS10490	COG0803	Belongs to the bacterial solute-binding protein 9 family
DP112_RS10520	COG3290	protein histidine kinase activity
DP112_RS10540	COG1490	D-aminoacyl-tRNA deacylase activity
DP112_RS10550	COG0737	Belongs to the 5'-nucleotidase family
DP112_RS10560	COG1811	Na channel or pump
DP112_RS10565	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DP112_RS10590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DP112_RS10630	COG1328	CTP reductase activity
DP112_RS10635	COG1126	abc transporter atp-binding protein
DP112_RS10645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP112_RS10650	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP112_RS10670	COG1438	arginine binding
DP112_RS10675	COG0018	arginyl-trna synthetase
DP112_RS10695	COG1640	4-alpha-glucanotransferase
DP112_RS10700	COG2182	Extracellular solute-binding protein
DP112_RS10705	COG1175	transmembrane transport
DP112_RS10710	COG3833	ABC-type maltose transport systems, permease component
DP112_RS10715	COG5521	maltodextrose utilization protein MalA
DP112_RS10720	COG1609	Transcriptional regulator
DP112_RS10725	COG1523	belongs to the glycosyl hydrolase 13 family
DP112_RS10730	COG1780	Probably involved in ribonucleotide reductase function
DP112_RS10735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP112_RS10740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DP112_RS10745	COG2153	protein acetylation
DP112_RS10750	COG4989	oxidoreductase activity
DP112_RS10755	COG1216	Glycosyl transferase, family 2
DP112_RS10760	COG1472	Belongs to the glycosyl hydrolase 3 family
DP112_RS10800	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DP112_RS10815	COG0305	Participates in initiation and elongation during chromosome replication
DP112_RS10820	COG0359	binds to the 23S rRNA
DP112_RS10830	COG0445	tRNA wobble uridine modification
DP112_RS10835	COG0494	nUDIX hydrolase
DP112_RS10845	COG1051	belongs to the nudix hydrolase family
DP112_RS10850	COG1733	regulation of RNA biosynthetic process
DP112_RS10860	COG0482	sulfurtransferase activity
DP112_RS10865	COG1760	l-serine dehydratase
DP112_RS10870	COG1760	l-serine dehydratase
DP112_RS10880	COG0745	RESPONSE REGULATOR receiver
DP112_RS10885	COG3850	Histidine kinase
DP112_RS10885	COG5002	protein histidine kinase activity
DP112_RS10895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DP112_RS10900	COG1122	ATPase activity
DP112_RS10905	COG1122	ATPase activity
DP112_RS10910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DP112_RS10915	COG1426	Protein conserved in bacteria
DP112_RS10920	COG0612	Peptidase, M16
DP112_RS10925	COG0612	Peptidase, M16
DP112_RS10935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DP112_RS10940	COG0516	GMP reductase activity
DP112_RS10940	COG0517	IMP dehydrogenase activity
DP112_RS10950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP112_RS10955	COG0488	(ABC) transporter
DP112_RS10990	COG1674	ftsk spoiiie
DP112_RS11030	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DP112_RS11035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP112_RS11040	COG1475	DNA binding