locus-tag	class	description
A9494_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A9494_RS00010	COG0592	DNA-directed DNA polymerase activity
A9494_RS00030	COG0012	GTP binding
A9494_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
A9494_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A9494_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A9494_RS00065	COG0037	tRNA processing
A9494_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A9494_RS00190	COG1792	Involved in formation and maintenance of cell shape
A9494_RS00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A9494_RS00210	COG0436	Aminotransferase
A9494_RS00215	COG1381	Involved in DNA repair and RecF pathway recombination
A9494_RS00220	COG0416	fatty acid biosynthetic process
A9494_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A9494_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A9494_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A9494_RS00255	COG0138	bifunctional purine biosynthesis protein purh
A9494_RS00260	COG0151	Belongs to the GarS family
A9494_RS00265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A9494_RS00285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A9494_RS00310	COG1131	(ABC) transporter
A9494_RS00320	COG1132	(ABC) transporter
A9494_RS00325	COG2255	four-way junction helicase activity
A9494_RS00335	COG0546	phosphoglycolate phosphatase activity
A9494_RS00360	COG0285	dihydrofolate synthase activity
A9494_RS00375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A9494_RS00380	COG0632	four-way junction helicase activity
A9494_RS00390	COG0519	Catalyzes the synthesis of GMP from XMP
A9494_RS00405	COG1393	Belongs to the ArsC family
A9494_RS00410	COG4472	Bacterial protein of unknown function (DUF965)
A9494_RS00415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A9494_RS00420	COG3906	Belongs to the UPF0473 family
A9494_RS00445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A9494_RS00450	COG0088	Forms part of the polypeptide exit tunnel
A9494_RS00455	COG0089	rRNA binding
A9494_RS00460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A9494_RS00465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A9494_RS00470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A9494_RS00475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A9494_RS00480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A9494_RS00485	COG0255	Belongs to the universal ribosomal protein uL29 family
A9494_RS00490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A9494_RS00495	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A9494_RS00500	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A9494_RS00505	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A9494_RS00510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A9494_RS00520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A9494_RS00530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A9494_RS00535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A9494_RS00540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A9494_RS00545	COG1841	ribosomal large subunit assembly
A9494_RS00555	COG0201	protein transport
A9494_RS00560	COG0563	adenylate kinase activity
A9494_RS00565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A9494_RS00570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A9494_RS00575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A9494_RS00585	COG0202	RNA polymerase activity
A9494_RS00680	COG0582	viral genome integration into host DNA
A9494_RS00690	COG2946	Replication initiation factor
A9494_RS00735	COG1121	(ABC) transporter
A9494_RS00740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A9494_RS00745	COG0803	Belongs to the bacterial solute-binding protein 9 family
A9494_RS00745	COG3443	Belongs to the bacterial solute-binding protein 9 family
A9494_RS00775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9494_RS00785	COG0085	RNA polymerase activity
A9494_RS00790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A9494_RS00805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A9494_RS00810	COG1459	type II secretion system
A9494_RS00815	COG4537	Required for transformation and DNA binding
A9494_RS00845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A9494_RS00855	COG0285	dihydrofolate synthase activity
A9494_RS00860	COG1363	Peptidase, m42
A9494_RS00870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9494_RS00880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9494_RS00905	COG0459	protein refolding
A9494_RS00915	COG0049	tRNA binding
A9494_RS00920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A9494_RS00925	COG3590	peptidase
A9494_RS00935	COG0126	phosphoglycerate kinase activity
A9494_RS00945	COG0789	Transcriptional regulator
A9494_RS00950	COG0174	glutamine synthetase
A9494_RS00965	COG1214	PFAM Peptidase M22, glycoprotease
A9494_RS00975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A9494_RS00980	COG2207	Transcriptional regulator
A9494_RS00990	COG1175	transmembrane transport
A9494_RS00995	COG0395	ABC-type sugar transport system, permease component
A9494_RS01015	COG2855	membrane
A9494_RS01040	COG1131	(ABC) transporter
A9494_RS01045	COG2081	HI0933 family
A9494_RS01050	COG2723	6-phospho-beta-galactosidase activity
A9494_RS01060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9494_RS01075	COG3959	Transketolase, thiamine diphosphate binding domain
A9494_RS01080	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A9494_RS01085	COG0584	glycerophosphoryl diester phosphodiesterase
A9494_RS01090	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A9494_RS01095	COG2222	sugar isomerase
A9494_RS01125	COG1882	Formate acetyltransferase
A9494_RS01140	COG2910	NAD(P)H-binding
A9494_RS01165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9494_RS01200	COG0363	glucosamine-6-phosphate deaminase activity
A9494_RS01210	COG2217	Heavy metal translocating P-type atpase
A9494_RS01215	COG2217	Heavy metal translocating P-type atpase
A9494_RS01220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A9494_RS01225	COG0681	Belongs to the peptidase S26 family
A9494_RS01245	COG0366	Alpha amylase catalytic
A9494_RS01250	COG1263	PTS System
A9494_RS01250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9494_RS01255	COG2188	Transcriptional regulator
A9494_RS01270	COG1193	negative regulation of DNA recombination
A9494_RS01280	COG3118	belongs to the thioredoxin family
A9494_RS01285	COG0318	PFAM AMP-dependent synthetase and ligase
A9494_RS01290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9494_RS01290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9494_RS01315	COG1115	amino acid carrier protein
A9494_RS01320	COG0668	transmembrane transport
A9494_RS01335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A9494_RS01340	COG0167	dihydroorotate dehydrogenase activity
A9494_RS01345	COG2843	Capsule synthesis protein
A9494_RS01350	COG0561	phosphatase activity
A9494_RS01365	COG1131	(ABC) transporter
A9494_RS01370	COG1309	transcriptional regulator
A9494_RS01375	COG1511	domain protein
A9494_RS01400	COG1346	cytolysis
A9494_RS01405	COG2116	formate transmembrane transporter activity
A9494_RS01410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A9494_RS01415	COG0433	COG0433 Predicted ATPase
A9494_RS01420	COG0494	nUDIX hydrolase
A9494_RS01445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A9494_RS01450	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A9494_RS01455	COG0124	histidyl-tRNA synthetase
A9494_RS01460	COG1064	alcohol dehydrogenase
A9494_RS01465	COG1454	alcohol dehydrogenase
A9494_RS01465	COG1012	belongs to the aldehyde dehydrogenase family
A9494_RS01475	COG4988	ABC transporter
A9494_RS01480	COG1132	(ABC) transporter
A9494_RS01495	COG1129	ABC transporter
A9494_RS01500	COG0534	Mate efflux family protein
A9494_RS01505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A9494_RS01520	COG1304	FMN binding
A9494_RS01525	COG1132	(ABC) transporter
A9494_RS01530	COG1132	(ABC) transporter
A9494_RS01535	COG3830	Belongs to the UPF0237 family
A9494_RS01540	COG2848	UPF0210 protein
A9494_RS01545	COG0588	phosphoglycerate mutase activity
A9494_RS01550	COG1420	regulation of RNA biosynthetic process
A9494_RS01555	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A9494_RS01560	COG0443	Heat shock 70 kDa protein
A9494_RS01565	COG0484	heat shock protein binding
A9494_RS01575	COG0095	Lipoate-protein ligase
A9494_RS01585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9494_RS01590	COG0765	amino acid transport
A9494_RS01595	COG3655	Transcriptional regulator
A9494_RS01605	COG2217	Heavy metal translocating P-type atpase
A9494_RS01630	COG4475	Protein of unknown function (DUF436)
A9494_RS01660	COG4221	oxidoreductase activity
A9494_RS01665	COG0446	pyridine nucleotide-disulphide oxidoreductase
A9494_RS01665	COG1902	pentaerythritol trinitrate reductase activity
A9494_RS01670	COG1959	2 iron, 2 sulfur cluster binding
A9494_RS01690	COG0544	peptidyl-prolyl cis-trans isomerase activity
A9494_RS01710	COG3343	RNA polymerase activity
A9494_RS01715	COG0504	CTP synthase activity
A9494_RS01725	COG0191	fructose-bisphosphate aldolase activity
A9494_RS01730	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A9494_RS01765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A9494_RS01770	COG0252	asparaginase activity
A9494_RS01785	COG0589	response to stress
A9494_RS01790	COG0436	Aminotransferase
A9494_RS01795	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A9494_RS01800	COG1335	isochorismatase
A9494_RS01805	COG0335	large ribosomal subunit rRNA binding
A9494_RS01815	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A9494_RS01820	COG0154	amidase activity
A9494_RS01825	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A9494_RS01830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A9494_RS01835	COG1609	Transcriptional regulator
A9494_RS01840	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A9494_RS01845	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A9494_RS01855	COG3142	Participates in the control of copper homeostasis
A9494_RS01870	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A9494_RS01880	COG1534	Rna-binding protein
A9494_RS01885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A9494_RS01890	COG1713	HD superfamily hydrolase involved in NAD metabolism
A9494_RS01915	COG0799	negative regulation of ribosome biogenesis
A9494_RS01920	COG2226	methyltransferase
A9494_RS01925	COG5290	Psort location Cytoplasmic, score
A9494_RS01935	COG0789	Transcriptional regulator
A9494_RS01940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A9494_RS01960	COG0242	peptide deformylase activity
A9494_RS01970	COG1640	4-alpha-glucanotransferase
A9494_RS01975	COG0058	SHG alpha-glucan phosphorylase activity
A9494_RS01990	COG2190	(PTS) system
A9494_RS01990	COG1263	PTS System
A9494_RS01990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9494_RS02005	COG0217	transcriptional regulatory protein
A9494_RS02015	COG4720	Psort location CytoplasmicMembrane, score
A9494_RS02025	COG1054	Belongs to the UPF0176 family
A9494_RS02035	COG1122	ATPase activity
A9494_RS02050	COG0357	Ribosomal RNA small subunit methyltransferase G
A9494_RS02055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9494_RS02060	COG3331	DNA recombination
A9494_RS02065	COG4474	Belongs to the UPF0398 family
A9494_RS02070	COG3599	regulation of cell shape
A9494_RS02080	COG0116	Belongs to the methyltransferase superfamily
A9494_RS02090	COG1854	S-ribosylhomocysteine lyase activity
A9494_RS02095	COG1418	mRNA catabolic process
A9494_RS02105	COG1758	RNA polymerase activity
A9494_RS02110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A9494_RS02115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A9494_RS02120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A9494_RS02120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A9494_RS02125	COG0631	protein serine/threonine phosphatase activity
A9494_RS02130	COG0515	serine threonine protein kinase
A9494_RS02130	COG2815	serine threonine protein kinase
A9494_RS02155	COG1098	S1 RNA binding domain
A9494_RS02165	COG1739	Uncharacterized protein family UPF0029
A9494_RS02170	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A9494_RS02250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9494_RS02255	COG2137	regulation of response to DNA damage stimulus
A9494_RS02260	COG3557	Belongs to the UPF0374 family
A9494_RS02270	COG2188	Transcriptional regulator
A9494_RS02275	COG2188	Transcriptional regulator
A9494_RS02285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9494_RS02295	COG3716	PTS system mannose fructose sorbose family IID component
A9494_RS02305	COG2017	converts alpha-aldose to the beta-anomer
A9494_RS02320	COG0346	lactoylglutathione lyase activity
A9494_RS02370	COG1217	gtp-binding protein TYPA
A9494_RS02385	COG0681	Belongs to the peptidase S26 family
A9494_RS02420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A9494_RS02435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A9494_RS02440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A9494_RS02445	COG1799	cell septum assembly
A9494_RS02460	COG3599	regulation of cell shape
A9494_RS02480	COG0494	nUDIX hydrolase
A9494_RS02480	COG0406	alpha-ribazole phosphatase activity
A9494_RS02485	COG0542	response to heat
A9494_RS02490	COG4703	Protein of unknown function (DUF1797)
A9494_RS02495	COG0765	amino acid transport
A9494_RS02505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A9494_RS02545	COG0789	Transcriptional regulator
A9494_RS02560	COG0826	peptidase U32
A9494_RS02575	COG4443	Transcriptional Coactivator p15 (PC4)
A9494_RS02580	COG1268	BioY protein
A9494_RS02585	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A9494_RS02590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9494_RS02595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9494_RS02600	COG1136	(ABC) transporter
A9494_RS02605	COG0577	efflux transmembrane transporter activity
A9494_RS02620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A9494_RS02630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A9494_RS02640	COG3859	Proton-coupled thiamine transporter YuaJ
A9494_RS02660	COG0772	Belongs to the SEDS family
A9494_RS02665	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A9494_RS02670	COG1595	DNA-templated transcription, initiation
A9494_RS02680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A9494_RS02685	COG0149	triose-phosphate isomerase activity
A9494_RS02695	COG1078	dGTPase activity
A9494_RS02710	COG2826	transposase and inactivated derivatives, IS30 family
A9494_RS02715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A9494_RS02725	COG1131	(ABC) transporter
A9494_RS02730	COG2188	Transcriptional regulator
A9494_RS02740	COG0205	6-phosphofructokinase activity
A9494_RS02745	COG0469	pyruvate kinase activity
A9494_RS02755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9494_RS02760	COG2755	lipolytic protein G-D-S-L family
A9494_RS02760	COG0657	acetylesterase activity
A9494_RS02770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A9494_RS02775	COG0765	amino acid transport
A9494_RS02780	COG1126	abc transporter atp-binding protein
A9494_RS02785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9494_RS02805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A9494_RS02810	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A9494_RS02815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9494_RS02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9494_RS02835	COG3022	response to hydroperoxide
A9494_RS02845	COG3944	biosynthesis protein
A9494_RS02855	COG4464	protein tyrosine phosphatase activity
A9494_RS02870	COG0438	transferase activity, transferring glycosyl groups
A9494_RS02885	COG1216	Glycosyl transferase, family 2
A9494_RS02885	COG1442	glycosyl transferase family 8
A9494_RS02890	COG1216	Glycosyl transferase, family 2
A9494_RS02890	COG1442	glycosyl transferase family 8
A9494_RS02925	COG2089	acid synthase
A9494_RS02940	COG2755	lipolytic protein G-D-S-L family
A9494_RS02940	COG1083	cytidylyl-transferase
A9494_RS03015	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A9494_RS03020	COG0077	Prephenate dehydratase
A9494_RS03030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9494_RS03040	COG0562	UDP-galactopyranose mutase
A9494_RS03045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A9494_RS03065	COG0436	Aminotransferase
A9494_RS03075	COG0017	Asparaginyl-tRNA synthetase
A9494_RS03095	COG0534	Mate efflux family protein
A9494_RS03100	COG0251	oxidation-reduction process
A9494_RS03105	COG1660	Displays ATPase and GTPase activities
A9494_RS03110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A9494_RS03115	COG1481	regulation of sporulation
A9494_RS03130	COG0454	-acetyltransferase
A9494_RS03135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A9494_RS03140	COG0549	Belongs to the carbamate kinase family
A9494_RS03145	COG1288	antiporter activity
A9494_RS03150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A9494_RS03155	COG3583	domain protein
A9494_RS03155	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A9494_RS03155	COG3064	Membrane
A9494_RS03160	COG1438	arginine binding
A9494_RS03165	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A9494_RS03170	COG0363	glucosamine-6-phosphate deaminase activity
A9494_RS03205	COG1696	Membrane protein involved in D-alanine export
A9494_RS03210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A9494_RS03215	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A9494_RS03225	COG0435	Glutathione S-transferase
A9494_RS03230	COG1187	pseudouridine synthase activity
A9494_RS03235	COG0386	Belongs to the glutathione peroxidase family
A9494_RS03240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9494_RS03245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9494_RS03250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A9494_RS03255	COG1120	ATPase activity
A9494_RS03260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A9494_RS03265	COG0204	Acyl-transferase
A9494_RS03270	COG1555	photosystem II stabilization
A9494_RS03270	COG1596	polysaccharide export
A9494_RS03275	COG0658	competence protein
A9494_RS03275	COG2333	competence protein COMEC
A9494_RS03280	COG0517	IMP dehydrogenase activity
A9494_RS03295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9494_RS03300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A9494_RS03305	COG0470	DNA polymerase III
A9494_RS03310	COG4467	Involved in initiation control of chromosome replication
A9494_RS03320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A9494_RS03330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A9494_RS03335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A9494_RS03340	COG1393	Belongs to the ArsC family
A9494_RS03350	COG0708	Exodeoxyribonuclease III
A9494_RS03360	COG0531	amino acid
A9494_RS03425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9494_RS03430	COG4684	Psort location CytoplasmicMembrane, score
A9494_RS03435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A9494_RS03445	COG2759	Belongs to the formate--tetrahydrofolate ligase family
A9494_RS03455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9494_RS03460	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A9494_RS03470	COG0732	type I restriction modification DNA specificity domain
A9494_RS03505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A9494_RS03510	COG1349	DNA-binding transcription factor activity
A9494_RS03520	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9494_RS03525	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9494_RS03530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9494_RS03535	COG1882	Formate acetyltransferase
A9494_RS03555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A9494_RS03560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A9494_RS03565	COG0446	pyridine nucleotide-disulphide oxidoreductase
A9494_RS03575	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A9494_RS03580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A9494_RS03585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A9494_RS03590	COG0346	lactoylglutathione lyase activity
A9494_RS03600	COG1164	Oligoendopeptidase f
A9494_RS03615	COG0210	DNA helicase
A9494_RS03630	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A9494_RS03645	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A9494_RS03660	COG1122	ATPase activity
A9494_RS03665	COG1122	ATPase activity
A9494_RS03670	COG1011	Hydrolase
A9494_RS03700	COG1131	(ABC) transporter
A9494_RS03730	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A9494_RS03735	COG1074	ATP-dependent DNA helicase activity
A9494_RS03745	COG0187	DNA topoisomerase II activity
A9494_RS03770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A9494_RS03780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9494_RS03800	COG0539	negative regulation of cytoplasmic translation
A9494_RS03825	COG1104	cysteine desulfurase activity
A9494_RS03830	COG0301	tRNA thio-modification
A9494_RS03835	COG1114	Component of the transport system for branched-chain amino acids
A9494_RS03840	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A9494_RS03845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A9494_RS03865	COG0564	pseudouridine synthase activity
A9494_RS03870	COG2824	Alkylphosphonate utilization operon protein PhnA
A9494_RS03880	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A9494_RS03885	COG0540	Belongs to the ATCase OTCase family
A9494_RS03890	COG0505	Belongs to the CarA family
A9494_RS03900	COG2136	Putative SAM-dependent methyltransferase
A9494_RS03900	COG2521	methyltransferase
A9494_RS03905	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A9494_RS03915	COG0228	four-way junction DNA binding
A9494_RS03930	COG1132	(ABC) transporter
A9494_RS03935	COG0726	polysaccharide deacetylase
A9494_RS03940	COG0460	homoserine dehydrogenase
A9494_RS03945	COG0083	homoserine kinase activity
A9494_RS03950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A9494_RS03955	COG3842	ATPase activity
A9494_RS03960	COG1176	ABC-type spermidine putrescine transport system, permease component I
A9494_RS03965	COG1177	transmembrane transport
A9494_RS03975	COG0038	chloride channel
A9494_RS03990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A9494_RS03995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A9494_RS04010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A9494_RS04015	COG0336	Belongs to the RNA methyltransferase TrmD family
A9494_RS04020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A9494_RS04025	COG1349	DNA-binding transcription factor activity
A9494_RS04030	COG1105	Belongs to the carbohydrate kinase PfkB family
A9494_RS04035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9494_RS04035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9494_RS04035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9494_RS04045	COG1307	EDD domain protein, DegV family
A9494_RS04050	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A9494_RS04055	COG0617	tRNA 3'-terminal CCA addition
A9494_RS04060	COG0488	(ABC) transporter
A9494_RS04070	COG1940	carbohydrate kinase activity
A9494_RS04085	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A9494_RS04090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A9494_RS04100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A9494_RS04120	COG0481	GTPase activity
A9494_RS04145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A9494_RS04150	COG2890	protein-(glutamine-N5) methyltransferase activity
A9494_RS04155	COG0009	L-threonylcarbamoyladenylate synthase
A9494_RS04165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A9494_RS04175	COG0741	lytic transglycosylase activity
A9494_RS04180	COG4221	oxidoreductase activity
A9494_RS04205	COG1401	restriction endodeoxyribonuclease activity
A9494_RS04210	COG4268	DNA restriction-modification system
A9494_RS04220	COG2188	Transcriptional regulator
A9494_RS04225	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
A9494_RS04230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A9494_RS04245	COG1660	Displays ATPase and GTPase activities
A9494_RS04260	COG4974	Belongs to the 'phage' integrase family
A9494_RS04275	COG0745	RESPONSE REGULATOR receiver
A9494_RS04295	COG1136	(ABC) transporter
A9494_RS04335	COG2382	esterase
A9494_RS04345	COG3708	Transcriptional regulator
A9494_RS04345	COG2207	Transcriptional regulator
A9494_RS04350	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A9494_RS04355	COG0647	UMP catabolic process
A9494_RS04360	COG4974	Belongs to the 'phage' integrase family
A9494_RS04370	COG1396	sequence-specific DNA binding
A9494_RS04395	COG1131	(ABC) transporter
A9494_RS04400	COG1132	(ABC) transporter
A9494_RS04405	COG3843	relaxase mobilization nuclease domain protein
A9494_RS04475	COG0741	lytic transglycosylase activity
A9494_RS04475	COG0791	NLP P60 protein
A9494_RS04505	COG2946	Replication initiation factor
A9494_RS04515	COG1674	ftsk spoiiie
A9494_RS04550	COG0542	response to heat
A9494_RS04555	COG1396	sequence-specific DNA binding
A9494_RS04585	COG2197	response regulator
A9494_RS04610	COG1132	(ABC) transporter
A9494_RS04710	COG0270	DNA (cytosine-5-)-methyltransferase activity
A9494_RS04730	COG0222	ribosome binding
A9494_RS04735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A9494_RS04740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A9494_RS04745	COG0758	DNA mediated transformation
A9494_RS04750	COG0110	maltose O-acetyltransferase activity
A9494_RS04755	COG1937	Protein conserved in bacteria
A9494_RS04765	COG0446	pyridine nucleotide-disulphide oxidoreductase
A9494_RS04775	COG1272	protein, Hemolysin III
A9494_RS04785	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A9494_RS04790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A9494_RS04805	COG0737	Belongs to the 5'-nucleotidase family
A9494_RS04815	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A9494_RS04820	COG0463	Glycosyl transferase, family 2
A9494_RS04830	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A9494_RS04835	COG0284	orotidine-5'-phosphate decarboxylase activity
A9494_RS04840	COG0167	dihydroorotate dehydrogenase activity
A9494_RS04865	COG0297	glycogen (starch) synthase activity
A9494_RS04875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9494_RS04880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9494_RS04895	COG3583	domain protein
A9494_RS04920	COG1126	abc transporter atp-binding protein
A9494_RS04930	COG0488	(ABC) transporter
A9494_RS04935	COG2873	o-acetylhomoserine
A9494_RS04960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9494_RS04960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9494_RS04970	COG3711	transcriptional antiterminator
A9494_RS04975	COG3684	Belongs to the aldolase LacD family
A9494_RS04985	COG0698	ribose 5-phosphate isomerase
A9494_RS04990	COG0698	ribose 5-phosphate isomerase
A9494_RS05000	COG1349	DNA-binding transcription factor activity
A9494_RS05035	COG1396	sequence-specific DNA binding
A9494_RS05040	COG1194	a g-specific adenine glycosylase
A9494_RS05050	COG1132	(ABC) transporter
A9494_RS05055	COG1132	(ABC) transporter
A9494_RS05060	COG0280	phosphate acetyltransferase
A9494_RS05065	COG0564	pseudouridine synthase activity
A9494_RS05070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A9494_RS05075	COG2357	RelA SpoT domain protein
A9494_RS05080	COG4116	CYTH
A9494_RS05090	COG1104	cysteine desulfurase activity
A9494_RS05105	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
A9494_RS05110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A9494_RS05120	COG3764	Sortase (surface protein transpeptidase)
A9494_RS05125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A9494_RS05130	COG0039	L-malate dehydrogenase activity
A9494_RS05140	COG1079	Belongs to the binding-protein-dependent transport system permease family
A9494_RS05145	COG4603	Belongs to the binding-protein-dependent transport system permease family
A9494_RS05150	COG3845	ABC transporter
A9494_RS05155	COG1744	ABC transporter substrate-binding protein PnrA-like
A9494_RS05170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A9494_RS05175	COG2813	Specifically methylates the guanine in position
A9494_RS05180	COG1072	(Pantothenic acid kinase))
A9494_RS05205	COG5002	protein histidine kinase activity
A9494_RS05210	COG0745	RESPONSE REGULATOR receiver
A9494_RS05225	COG0704	Plays a role in the regulation of phosphate uptake
A9494_RS05230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A9494_RS05235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A9494_RS05240	COG0581	inorganic phosphate transmembrane transporter activity
A9494_RS05245	COG0573	inorganic phosphate transmembrane transporter activity
A9494_RS05255	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A9494_RS05255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A9494_RS05260	COG0483	inositol monophosphate 1-phosphatase activity
A9494_RS05265	COG4476	Belongs to the UPF0223 family
A9494_RS05270	COG1393	Belongs to the ArsC family
A9494_RS05275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A9494_RS05280	COG0196	riboflavin kinase activity
A9494_RS05285	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A9494_RS05345	COG0561	phosphatase activity
A9494_RS05350	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9494_RS05385	COG3759	membrane
A9494_RS05390	COG1846	Transcriptional regulator
A9494_RS05405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A9494_RS05410	COG2610	gluconate transmembrane transporter activity
A9494_RS05430	COG0302	gtp cyclohydrolase
A9494_RS05435	COG1051	belongs to the nudix hydrolase family
A9494_RS05460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9494_RS05460	COG0072	phenylalanine-tRNA ligase activity
A9494_RS05490	COG1028	Short-chain dehydrogenase reductase Sdr
A9494_RS05495	COG1312	Catalyzes the dehydration of D-mannonate
A9494_RS05505	COG0800	Aldolase
A9494_RS05515	COG3250	beta-galactosidase activity
A9494_RS05525	COG2211	Major facilitator Superfamily
A9494_RS05540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A9494_RS05550	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A9494_RS05555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A9494_RS05560	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A9494_RS05565	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A9494_RS05570	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A9494_RS05575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A9494_RS05580	COG0356	it plays a direct role in the translocation of protons across the membrane
A9494_RS05590	COG1597	lipid kinase activity
A9494_RS05600	COG0701	Predicted permease
A9494_RS05605	COG3689	TIGRFAM TIGR03943 family protein
A9494_RS05610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A9494_RS05625	COG0552	protein localization to endoplasmic reticulum
A9494_RS05630	COG0561	phosphatase activity
A9494_RS05635	COG0561	phosphatase activity
A9494_RS05640	COG1196	nuclear chromosome segregation
A9494_RS05665	COG2826	transposase and inactivated derivatives, IS30 family
A9494_RS05680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9494_RS05685	COG0538	isocitrate dehydrogenase activity
A9494_RS05690	COG0372	Belongs to the citrate synthase family
A9494_RS05695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A9494_RS05700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A9494_RS05705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9494_RS05715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9494_RS05720	COG1609	Transcriptional regulator
A9494_RS05735	COG5492	domain, Protein
A9494_RS05740	COG5492	domain, Protein
A9494_RS05745	COG5492	domain, Protein
A9494_RS05755	COG3716	PTS system mannose fructose sorbose family IID component
A9494_RS05765	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9494_RS05770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A9494_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
A9494_RS05835	COG1476	TRANSCRIPTIONal
A9494_RS05860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A9494_RS05870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9494_RS05875	COG4122	O-methyltransferase activity
A9494_RS05900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9494_RS05900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9494_RS05910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A9494_RS05915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A9494_RS05920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A9494_RS05925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A9494_RS05935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9494_RS05935	COG1116	anion transmembrane transporter activity
A9494_RS05940	COG4120	Belongs to the binding-protein-dependent transport system permease family
A9494_RS05960	COG3684	Belongs to the aldolase LacD family
A9494_RS05970	COG3679	Belongs to the UPF0342 family
A9494_RS05975	COG0287	Prephenate dehydrogenase
A9494_RS05980	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A9494_RS05985	COG0710	3-dehydroquinate dehydratase activity
A9494_RS05990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A9494_RS05995	COG1368	sulfuric ester hydrolase activity
A9494_RS06015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A9494_RS06025	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A9494_RS06070	COG1216	Glycosyl transferase, family 2
A9494_RS06070	COG1442	glycosyl transferase family 8
A9494_RS06075	COG1442	glycosyl transferase family 8
A9494_RS06105	COG0463	Glycosyl transferase, family 2
A9494_RS06135	COG1091	dTDP-4-dehydrorhamnose reductase activity
A9494_RS06140	COG1088	dTDP-glucose 4,6-dehydratase activity
A9494_RS06155	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A9494_RS06165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A9494_RS06170	COG2384	SAM-dependent methyltransferase
A9494_RS06185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A9494_RS06200	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A9494_RS06200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A9494_RS06205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9494_RS06215	COG0300	oxidoreductase activity
A9494_RS06220	COG1234	tRNA 3'-trailer cleavage
A9494_RS06230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A9494_RS06235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A9494_RS06245	COG2807	transmembrane transport
A9494_RS06250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A9494_RS06255	COG1702	phosphate starvation-inducible protein PhoH
A9494_RS06260	COG4479	Belongs to the UPF0346 family
A9494_RS06275	COG2996	Protein conserved in bacteria
A9494_RS06280	COG0233	cytoplasmic translational termination
A9494_RS06285	COG0528	UMP kinase activity
A9494_RS06290	COG2244	polysaccharide biosynthetic process
A9494_RS06295	COG0625	glutathione transferase activity
A9494_RS06320	COG0346	lactoylglutathione lyase activity
A9494_RS06325	COG1674	ftsk spoiiie
A9494_RS06325	COG0697	spore germination
A9494_RS06330	COG1621	beta-fructofuranosidase activity
A9494_RS06340	COG0395	ABC-type sugar transport system, permease component
A9494_RS06345	COG4209	transmembrane transport
A9494_RS06350	COG1609	Transcriptional regulator
A9494_RS06370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A9494_RS06385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A9494_RS06395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A9494_RS06405	COG1181	Belongs to the D-alanine--D-alanine ligase family
A9494_RS06410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A9494_RS06415	COG0768	penicillin binding
A9494_RS06425	COG0488	(ABC) transporter
A9494_RS06430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A9494_RS06440	COG0745	RESPONSE REGULATOR receiver
A9494_RS06445	COG1126	abc transporter atp-binding protein
A9494_RS06450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9494_RS06455	COG0765	amino acid transport
A9494_RS06460	COG0765	amino acid transport
A9494_RS06465	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A9494_RS06480	COG0438	transferase activity, transferring glycosyl groups
A9494_RS06495	COG1609	Transcriptional regulator
A9494_RS06505	COG0343	queuine tRNA-ribosyltransferase activity
A9494_RS06515	COG1832	CoA-binding protein
A9494_RS06525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9494_RS06525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9494_RS06540	COG1136	(ABC) transporter
A9494_RS06550	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A9494_RS06555	COG2217	Heavy metal translocating P-type atpase
A9494_RS06570	COG1063	alcohol dehydrogenase
A9494_RS06575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A9494_RS06580	COG0557	exoribonuclease II activity
A9494_RS06585	COG0017	Asparaginyl-tRNA synthetase
A9494_RS06595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A9494_RS06600	COG2814	Major facilitator Superfamily
A9494_RS06610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A9494_RS06615	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A9494_RS06620	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A9494_RS06630	COG1737	Transcriptional regulator
A9494_RS06640	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
A9494_RS06650	COG1011	Hydrolase
A9494_RS06655	COG1132	(ABC) transporter
A9494_RS06660	COG1132	(ABC) transporter
A9494_RS06690	COG2177	Part of the ABC transporter FtsEX involved in
A9494_RS06695	COG2884	Cell division ATP-binding protein ftsE
A9494_RS06700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A9494_RS06710	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A9494_RS06740	COG2826	transposase and inactivated derivatives, IS30 family
A9494_RS06775	COG2151	metal-sulfur cluster biosynthetic enzyme
A9494_RS06780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A9494_RS06785	COG0358	DNA primase activity
A9494_RS06790	COG1970	mechanosensitive ion channel activity
A9494_RS06795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9494_RS06800	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A9494_RS06810	COG0647	UMP catabolic process
A9494_RS06815	COG1051	belongs to the nudix hydrolase family
A9494_RS06825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A9494_RS06835	COG0058	SHG alpha-glucan phosphorylase activity
A9494_RS06840	COG0813	purine-nucleoside phosphorylase activity
A9494_RS06845	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A9494_RS06855	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A9494_RS06860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A9494_RS06865	COG0732	type I restriction modification DNA specificity domain
A9494_RS06885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A9494_RS06900	COG2268	Band 7 protein
A9494_RS06905	COG1704	LemA family
A9494_RS06915	COG1573	uracil-dna glycosylase
A9494_RS06950	COG2226	methyltransferase
A9494_RS06955	COG0488	(ABC) transporter
A9494_RS06960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9494_RS06975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A9494_RS06980	COG3442	glutamine amidotransferase
A9494_RS06990	COG2226	methyltransferase
A9494_RS07010	COG0488	(ABC) transporter
A9494_RS07045	COG3842	ATPase activity
A9494_RS07065	COG2190	(PTS) system
A9494_RS07065	COG1263	PTS System
A9494_RS07065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9494_RS07070	COG3711	transcriptional antiterminator
A9494_RS07075	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A9494_RS07080	COG3527	Alpha-acetolactate decarboxylase
A9494_RS07090	COG0628	permease
A9494_RS07095	COG2706	6-phosphogluconolactonase activity
A9494_RS07105	COG1011	Hydrolase
A9494_RS07150	COG0560	Phosphoserine phosphatase
A9494_RS07155	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A9494_RS07160	COG0187	DNA topoisomerase II activity
A9494_RS07165	COG0693	protein deglycase activity
A9494_RS07170	COG0772	Belongs to the SEDS family
A9494_RS07175	COG0582	viral genome integration into host DNA
A9494_RS07260	COG0582	viral genome integration into host DNA
A9494_RS07275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A9494_RS07280	COG0716	FMN binding
A9494_RS07290	COG1605	Chorismate mutase
A9494_RS07290	COG0287	Prephenate dehydrogenase
A9494_RS07295	COG0038	chloride channel
A9494_RS07305	COG0737	Belongs to the 5'-nucleotidase family
A9494_RS07310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A9494_RS07315	COG1466	dna polymerase III delta subunit
A9494_RS07350	COG0683	leucine binding
A9494_RS07365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A9494_RS07370	COG0366	Alpha amylase catalytic
A9494_RS07380	COG0395	ABC-type sugar transport system, permease component
A9494_RS07385	COG1175	transmembrane transport
A9494_RS07390	COG1653	transport
A9494_RS07400	COG2207	Transcriptional regulator
A9494_RS07405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A9494_RS07410	COG0626	cystathionine gamma-synthase activity
A9494_RS07430	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A9494_RS07435	COG2827	Endonuclease containing a URI domain
A9494_RS07460	COG0640	Transcriptional regulator
A9494_RS07465	COG0513	Belongs to the DEAD box helicase family
A9494_RS07475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9494_RS07515	COG0494	nUDIX hydrolase
A9494_RS07520	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A9494_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
A9494_RS07565	COG0577	efflux transmembrane transporter activity
A9494_RS07570	COG1136	(ABC) transporter
A9494_RS07575	COG2205	protein histidine kinase activity
A9494_RS07590	COG0436	Aminotransferase
A9494_RS07600	COG1174	glycine betaine transport
A9494_RS07605	COG1125	glycine betaine transport
A9494_RS07605	COG0517	IMP dehydrogenase activity
A9494_RS07625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A9494_RS07630	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A9494_RS07635	COG1482	cell wall glycoprotein biosynthetic process
A9494_RS07660	COG3091	SprT-like family
A9494_RS07665	COG2183	response to ionizing radiation
A9494_RS07670	COG0656	L-ascorbic acid biosynthetic process
A9494_RS07675	COG4708	membrane
A9494_RS07680	COG2246	polysaccharide biosynthetic process
A9494_RS07690	COG0024	Methionine aminopeptidase
A9494_RS07700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A9494_RS07705	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9494_RS07710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A9494_RS07715	COG2131	deaminase
A9494_RS07725	COG1363	Peptidase, m42
A9494_RS07740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A9494_RS07745	COG1956	GAF domain-containing protein
A9494_RS07755	COG1695	Transcriptional regulator
A9494_RS07770	COG0513	Belongs to the DEAD box helicase family
A9494_RS07775	COG0726	polysaccharide deacetylase
A9494_RS07795	COG0183	Belongs to the thiolase family
A9494_RS07800	COG3425	synthase
A9494_RS07830	COG0776	regulation of translation
A9494_RS07840	COG2755	lipolytic protein G-D-S-L family
A9494_RS07845	COG1307	EDD domain protein, DegV family
A9494_RS07850	COG0497	DNA recombination
A9494_RS07855	COG1438	arginine binding
A9494_RS07860	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A9494_RS07870	COG1722	exodeoxyribonuclease VII activity
A9494_RS07875	COG1570	exodeoxyribonuclease VII activity
A9494_RS07880	COG2321	neutral zinc metallopeptidase
A9494_RS07885	COG1755	Isoprenylcysteine carboxyl methyltransferase
A9494_RS07890	COG5002	protein histidine kinase activity
A9494_RS07895	COG0745	RESPONSE REGULATOR receiver
A9494_RS07920	COG1227	inorganic diphosphatase activity
A9494_RS07930	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A9494_RS07935	COG1253	flavin adenine dinucleotide binding
A9494_RS07940	COG1119	ATPase activity
A9494_RS07945	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A9494_RS07955	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A9494_RS07960	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A9494_RS07975	COG4470	Protein conserved in bacteria
A9494_RS07980	COG3480	Lon protease (S16) C-terminal proteolytic domain
A9494_RS07985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A9494_RS07990	COG0742	ribosomal rna small subunit methyltransferase
A9494_RS08000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9494_RS08005	COG4483	Protein conserved in bacteria
A9494_RS08010	COG2197	response regulator
A9494_RS08015	COG2203	Gaf domain
A9494_RS08015	COG4585	Histidine kinase
A9494_RS08020	COG0842	Transport permease protein
A9494_RS08025	COG1131	(ABC) transporter
A9494_RS08040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A9494_RS08055	COG0671	phosphoesterase, PA-phosphatase related
A9494_RS08060	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A9494_RS08075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A9494_RS08080	COG1187	pseudouridine synthase activity
A9494_RS08085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A9494_RS08090	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A9494_RS08095	COG0582	viral genome integration into host DNA
A9494_RS08115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A9494_RS08120	COG3763	UPF0154 protein
A9494_RS08130	COG3579	cysteine-type endopeptidase activity
A9494_RS08145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9494_RS08150	COG1254	Belongs to the acylphosphatase family
A9494_RS08160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A9494_RS08165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A9494_RS08175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A9494_RS08185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9494_RS08200	COG1160	GTP binding
A9494_RS08210	COG0778	Nitroreductase
A9494_RS08215	COG1484	DNA-dependent DNA replication
A9494_RS08225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A9494_RS08230	COG0628	permease
A9494_RS08235	COG0745	RESPONSE REGULATOR receiver
A9494_RS08240	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A9494_RS08250	COG0492	ferredoxin-NADP+ reductase activity
A9494_RS08260	COG0513	Belongs to the DEAD box helicase family
A9494_RS08270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9494_RS08275	COG0768	penicillin binding
A9494_RS08285	COG0275	rRNA processing
A9494_RS08335	COG4939	FMN-binding domain protein
A9494_RS08340	COG0142	geranyltranstransferase activity
A9494_RS08345	COG1252	NADH dehydrogenase
A9494_RS08360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9494_RS08365	COG0569	domain protein
A9494_RS08370	COG0534	Mate efflux family protein
A9494_RS08380	COG4224	UPF0291 protein
A9494_RS08385	COG0751	glycine-tRNA ligase activity
A9494_RS08410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A9494_RS08415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A9494_RS08420	COG1464	Belongs to the NlpA lipoprotein family
A9494_RS08425	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A9494_RS08430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A9494_RS08435	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A9494_RS08440	COG2252	PERMEase
A9494_RS08445	COG0561	phosphatase activity
A9494_RS08455	COG3715	PTS system
A9494_RS08460	COG3716	PTS system mannose fructose sorbose family IID component
A9494_RS08485	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A9494_RS08530	COG0439	Biotin carboxylase
A9494_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
A9494_RS08555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A9494_RS08560	COG2070	2-Nitropropane dioxygenase
A9494_RS08570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9494_RS08580	COG1024	Enoyl-CoA hydratase
A9494_RS08585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9494_RS08590	COG0527	aspartate kinase activity
A9494_RS08600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A9494_RS08605	COG0736	holo-[acyl-carrier-protein] synthase activity
A9494_RS08610	COG0653	protein targeting
A9494_RS08620	COG1940	carbohydrate kinase activity
A9494_RS08625	COG1263	PTS System
A9494_RS08625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9494_RS08625	COG2190	(PTS) system
A9494_RS08630	COG1621	beta-fructofuranosidase activity
A9494_RS08635	COG1609	Transcriptional regulator
A9494_RS08640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A9494_RS08655	COG0006	proline dipeptidase activity
A9494_RS08660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A9494_RS08680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A9494_RS08685	COG0629	single-stranded DNA binding
A9494_RS08695	COG2826	transposase and inactivated derivatives, IS30 family
A9494_RS08700	COG0095	Lipoate-protein ligase
A9494_RS08715	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9494_RS08720	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9494_RS08720	COG0022	dehydrogenase e1 component
A9494_RS08725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A9494_RS08730	COG2860	membrane
A9494_RS08745	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A9494_RS08750	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A9494_RS08760	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A9494_RS08765	COG0195	Participates in both transcription termination and antitermination
A9494_RS08780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A9494_RS08790	COG4473	ABC transporter
A9494_RS08795	COG1131	(ABC) transporter
A9494_RS08800	COG0537	adenosine 5'-monophosphoramidase activity
A9494_RS08810	COG1316	TRANSCRIPTIONal
A9494_RS08820	COG0802	atpase or kinase
A9494_RS08825	COG1461	Dihydroxyacetone kinase
A9494_RS08840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9494_RS08845	COG0601	transmembrane transport
A9494_RS08850	COG4608	Belongs to the ABC transporter superfamily
A9494_RS08865	COG1686	Belongs to the peptidase S11 family
A9494_RS08880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A9494_RS08885	COG0719	Fe-S assembly protein
A9494_RS08895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9494_RS08900	COG4862	establishment of competence for transformation
A9494_RS08905	COG1968	undecaprenyl-diphosphatase activity
A9494_RS08910	COG0765	amino acid transport
A9494_RS08930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A9494_RS08935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A9494_RS08940	COG0440	acetolactate synthase activity
A9494_RS08945	COG0028	Belongs to the TPP enzyme family
A9494_RS08965	COG0129	dihydroxy-acid dehydratase activity
A9494_RS08975	COG2151	metal-sulfur cluster biosynthetic enzyme
A9494_RS08990	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A9494_RS09005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9494_RS09030	COG3842	ATPase activity
A9494_RS09040	COG2207	Transcriptional regulator
A9494_RS09040	COG4753	response regulator
A9494_RS09045	COG2972	Histidine kinase
A9494_RS09065	COG1653	transport
A9494_RS09070	COG0395	ABC-type sugar transport system, permease component
A9494_RS09075	COG1175	transmembrane transport
A9494_RS09090	COG0383	alpha-mannosidase activity
A9494_RS09110	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A9494_RS09130	COG1045	serine acetyltransferase
A9494_RS09135	COG1185	polyribonucleotide nucleotidyltransferase activity
A9494_RS09160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9494_RS09160	COG1263	PTS System
A9494_RS09170	COG1737	Transcriptional regulator
A9494_RS09175	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A9494_RS09195	COG1187	pseudouridine synthase activity
A9494_RS09215	COG0242	peptide deformylase activity
A9494_RS09225	COG0066	3-isopropylmalate dehydratase activity
A9494_RS09250	COG2309	aminopeptidase activity
A9494_RS09265	COG2176	DNA-directed DNA polymerase activity
A9494_RS09270	COG2376	Dihydroxyacetone kinase
A9494_RS09280	COG2376	Dihydroxyacetone kinase
A9494_RS09285	COG1461	Dihydroxyacetone kinase
A9494_RS09290	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
A9494_RS09295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A9494_RS09300	COG0442	prolyl-tRNA aminoacylation
A9494_RS09310	COG4589	Belongs to the CDS family
A9494_RS09315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A9494_RS09320	COG1862	Preprotein translocase
A9494_RS09330	COG2918	glutathione biosynthetic process
A9494_RS09330	COG1181	Belongs to the D-alanine--D-alanine ligase family
A9494_RS09340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A9494_RS09345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A9494_RS09360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A9494_RS09370	COG4463	regulation of RNA biosynthetic process
A9494_RS09385	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A9494_RS09420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A9494_RS09425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9494_RS09430	COG0492	ferredoxin-NADP+ reductase activity
A9494_RS09435	COG0564	pseudouridine synthase activity
A9494_RS09440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A9494_RS09460	COG1564	THIamine pyrophosphokinase
A9494_RS09470	COG1162	GTPase activity
A9494_RS09520	COG4115	mRNA cleavage
A9494_RS09555	COG0084	hydrolase, TatD family'
A9494_RS09565	COG1847	R3H domain protein
A9494_RS09575	COG0594	ribonuclease P activity
A9494_RS09580	COG0165	Argininosuccinate lyase
A9494_RS09585	COG0137	argininosuccinate synthase activity
A9494_RS09595	COG1827	regulation of RNA biosynthetic process
A9494_RS09610	COG2040	homocysteine
A9494_RS09615	COG0833	amino acid
A9494_RS09660	COG0756	dUTP diphosphatase activity
A9494_RS09665	COG1132	(ABC) transporter
A9494_RS09670	COG1132	(ABC) transporter
A9494_RS09680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A9494_RS09685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A9494_RS09690	COG0705	Rhomboid family
A9494_RS09695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A9494_RS09700	COG1473	amidohydrolase
A9494_RS09705	COG2171	N-acyltransferase activity
A9494_RS09720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A9494_RS09745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A9494_RS09770	COG3623	hexulose-6-phosphate isomerase
A9494_RS09795	COG1523	belongs to the glycosyl hydrolase 13 family
A9494_RS09800	COG1609	Transcriptional regulator
A9494_RS09805	COG1126	abc transporter atp-binding protein
A9494_RS09810	COG0765	amino acid transport
A9494_RS09815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9494_RS09820	COG3942	CHAP domain
A9494_RS09825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9494_RS09835	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9494_RS09845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9494_RS09845	COG3711	transcriptional antiterminator
A9494_RS09855	COG2723	6-phospho-beta-galactosidase activity
A9494_RS09860	COG1486	melibiose metabolic process
A9494_RS09870	COG3590	peptidase
A9494_RS09875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A9494_RS09880	COG1321	iron dependent repressor
A9494_RS09880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A9494_RS09885	COG1121	(ABC) transporter
A9494_RS09900	COG0803	Belongs to the bacterial solute-binding protein 9 family
A9494_RS09935	COG1490	D-aminoacyl-tRNA deacylase activity
A9494_RS09945	COG0737	Belongs to the 5'-nucleotidase family
A9494_RS10005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A9494_RS10030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A9494_RS10060	COG0737	Belongs to the 5'-nucleotidase family
A9494_RS10070	COG1328	CTP reductase activity
A9494_RS10100	COG1438	arginine binding
A9494_RS10105	COG0018	arginyl-trna synthetase
A9494_RS10125	COG1640	4-alpha-glucanotransferase
A9494_RS10130	COG2182	Extracellular solute-binding protein
A9494_RS10135	COG1175	transmembrane transport
A9494_RS10140	COG3833	ABC-type maltose transport systems, permease component
A9494_RS10145	COG5521	maltodextrose utilization protein MalA
A9494_RS10150	COG1609	Transcriptional regulator
A9494_RS10155	COG1523	belongs to the glycosyl hydrolase 13 family
A9494_RS10160	COG1780	Probably involved in ribonucleotide reductase function
A9494_RS10165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9494_RS10170	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A9494_RS10175	COG2153	protein acetylation
A9494_RS10180	COG4989	oxidoreductase activity
A9494_RS10185	COG1216	Glycosyl transferase, family 2
A9494_RS10190	COG1472	Belongs to the glycosyl hydrolase 3 family
A9494_RS10230	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A9494_RS10245	COG0305	Participates in initiation and elongation during chromosome replication
A9494_RS10250	COG0359	binds to the 23S rRNA
A9494_RS10260	COG0445	tRNA wobble uridine modification
A9494_RS10275	COG1051	belongs to the nudix hydrolase family
A9494_RS10280	COG1733	regulation of RNA biosynthetic process
A9494_RS10290	COG0482	sulfurtransferase activity
A9494_RS10295	COG1760	l-serine dehydratase
A9494_RS10300	COG1760	l-serine dehydratase
A9494_RS10310	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A9494_RS10315	COG1122	ATPase activity
A9494_RS10320	COG1122	ATPase activity
A9494_RS10325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A9494_RS10330	COG1426	Protein conserved in bacteria
A9494_RS10335	COG0612	Peptidase, M16
A9494_RS10340	COG0612	Peptidase, M16
A9494_RS10350	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A9494_RS10355	COG0516	GMP reductase activity
A9494_RS10355	COG0517	IMP dehydrogenase activity
A9494_RS10365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9494_RS10370	COG0488	(ABC) transporter
A9494_RS10405	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A9494_RS10410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9494_RS10415	COG1475	DNA binding