locus-tag	class	description
AA105_RS00005	COG1475	DNA binding
AA105_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AA105_RS00015	COG0592	DNA-directed DNA polymerase activity
AA105_RS00035	COG0012	GTP binding
AA105_RS00040	COG0193	aminoacyl-tRNA hydrolase activity
AA105_RS00045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AA105_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AA105_RS00070	COG0037	tRNA processing
AA105_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AA105_RS00190	COG1792	Involved in formation and maintenance of cell shape
AA105_RS00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AA105_RS00210	COG0436	Aminotransferase
AA105_RS00215	COG1381	Involved in DNA repair and RecF pathway recombination
AA105_RS00220	COG0416	fatty acid biosynthetic process
AA105_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AA105_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AA105_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AA105_RS00255	COG0138	bifunctional purine biosynthesis protein purh
AA105_RS00280	COG0151	Belongs to the GarS family
AA105_RS00285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AA105_RS00300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AA105_RS00330	COG1131	(ABC) transporter
AA105_RS00340	COG1132	(ABC) transporter
AA105_RS00345	COG2255	four-way junction helicase activity
AA105_RS00355	COG0546	phosphoglycolate phosphatase activity
AA105_RS00365	COG0285	dihydrofolate synthase activity
AA105_RS00380	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AA105_RS00385	COG0632	four-way junction helicase activity
AA105_RS00390	COG0519	Catalyzes the synthesis of GMP from XMP
AA105_RS00405	COG1393	Belongs to the ArsC family
AA105_RS00410	COG4472	Bacterial protein of unknown function (DUF965)
AA105_RS00415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AA105_RS00420	COG3906	Belongs to the UPF0473 family
AA105_RS00435	COG0051	transcription antitermination factor activity, RNA binding
AA105_RS00440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AA105_RS00445	COG0088	Forms part of the polypeptide exit tunnel
AA105_RS00450	COG0089	rRNA binding
AA105_RS00455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AA105_RS00460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AA105_RS00465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AA105_RS00470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AA105_RS00475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AA105_RS00480	COG0255	Belongs to the universal ribosomal protein uL29 family
AA105_RS00485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AA105_RS00490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AA105_RS00495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AA105_RS00500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AA105_RS00505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AA105_RS00515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AA105_RS00525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AA105_RS00530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AA105_RS00535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AA105_RS00540	COG1841	ribosomal large subunit assembly
AA105_RS00550	COG0201	protein transport
AA105_RS00555	COG0563	adenylate kinase activity
AA105_RS00560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AA105_RS00565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AA105_RS00570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AA105_RS00580	COG0202	RNA polymerase activity
AA105_RS00685	COG0582	viral genome integration into host DNA
AA105_RS00695	COG2946	Replication initiation factor
AA105_RS00735	COG1121	(ABC) transporter
AA105_RS00740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AA105_RS00745	COG3443	Belongs to the bacterial solute-binding protein 9 family
AA105_RS00745	COG0803	Belongs to the bacterial solute-binding protein 9 family
AA105_RS00770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AA105_RS00775	COG0085	RNA polymerase activity
AA105_RS00780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AA105_RS00790	COG1619	proteins homologs of microcin C7 resistance protein MccF
AA105_RS00795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AA105_RS00800	COG1459	type II secretion system
AA105_RS00805	COG4537	Required for transformation and DNA binding
AA105_RS00835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AA105_RS00845	COG0285	dihydrofolate synthase activity
AA105_RS00850	COG1363	Peptidase, m42
AA105_RS00860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AA105_RS00870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AA105_RS00895	COG0459	protein refolding
AA105_RS00905	COG0049	tRNA binding
AA105_RS00910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AA105_RS00915	COG3590	peptidase
AA105_RS00925	COG0126	phosphoglycerate kinase activity
AA105_RS00935	COG0789	Transcriptional regulator
AA105_RS00940	COG0174	glutamine synthetase
AA105_RS00955	COG1214	PFAM Peptidase M22, glycoprotease
AA105_RS00965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AA105_RS00970	COG2207	Transcriptional regulator
AA105_RS00980	COG1175	transmembrane transport
AA105_RS00985	COG0395	ABC-type sugar transport system, permease component
AA105_RS01005	COG2855	membrane
AA105_RS01015	COG1131	(ABC) transporter
AA105_RS01025	COG2081	HI0933 family
AA105_RS01030	COG2723	6-phospho-beta-galactosidase activity
AA105_RS01040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AA105_RS01055	COG3959	Transketolase, thiamine diphosphate binding domain
AA105_RS01060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AA105_RS01065	COG0584	glycerophosphoryl diester phosphodiesterase
AA105_RS01070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AA105_RS01075	COG2222	sugar isomerase
AA105_RS01100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AA105_RS01110	COG3942	CHAP domain
AA105_RS01115	COG1882	Formate acetyltransferase
AA105_RS01130	COG2910	NAD(P)H-binding
AA105_RS01155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AA105_RS01190	COG0363	glucosamine-6-phosphate deaminase activity
AA105_RS01195	COG2217	Heavy metal translocating P-type atpase
AA105_RS01205	COG2217	Heavy metal translocating P-type atpase
AA105_RS01210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AA105_RS01215	COG0681	Belongs to the peptidase S26 family
AA105_RS01235	COG0366	Alpha amylase catalytic
AA105_RS01240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AA105_RS01240	COG1263	PTS System
AA105_RS01245	COG2188	Transcriptional regulator
AA105_RS01260	COG1193	negative regulation of DNA recombination
AA105_RS01325	COG3118	belongs to the thioredoxin family
AA105_RS01335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AA105_RS01335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AA105_RS01395	COG1115	amino acid carrier protein
AA105_RS01430	COG3842	ATPase activity
AA105_RS01440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AA105_RS01455	COG0668	transmembrane transport
AA105_RS01470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AA105_RS01475	COG0167	dihydroorotate dehydrogenase activity
AA105_RS01480	COG2843	Capsule synthesis protein
AA105_RS01485	COG0561	phosphatase activity
AA105_RS01500	COG1131	(ABC) transporter
AA105_RS01505	COG1309	transcriptional regulator
AA105_RS01525	COG1511	domain protein
AA105_RS01550	COG1346	cytolysis
AA105_RS01555	COG2116	formate transmembrane transporter activity
AA105_RS01560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AA105_RS01565	COG0433	COG0433 Predicted ATPase
AA105_RS01570	COG0494	nUDIX hydrolase
AA105_RS01590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AA105_RS01595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AA105_RS01600	COG0124	histidyl-tRNA synthetase
AA105_RS01605	COG1064	alcohol dehydrogenase
AA105_RS01610	COG1012	belongs to the aldehyde dehydrogenase family
AA105_RS01610	COG1454	alcohol dehydrogenase
AA105_RS01630	COG1132	(ABC) transporter
AA105_RS01640	COG0534	Mate efflux family protein
AA105_RS01645	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AA105_RS01660	COG1304	FMN binding
AA105_RS01665	COG1132	(ABC) transporter
AA105_RS01670	COG1132	(ABC) transporter
AA105_RS01675	COG3830	Belongs to the UPF0237 family
AA105_RS01680	COG2848	UPF0210 protein
AA105_RS01685	COG0588	phosphoglycerate mutase activity
AA105_RS01690	COG1420	regulation of RNA biosynthetic process
AA105_RS01695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AA105_RS01700	COG0443	Heat shock 70 kDa protein
AA105_RS01705	COG0484	heat shock protein binding
AA105_RS01710	COG0095	Lipoate-protein ligase
AA105_RS01720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AA105_RS01725	COG0765	amino acid transport
AA105_RS01740	COG3655	Transcriptional regulator
AA105_RS01750	COG2217	Heavy metal translocating P-type atpase
AA105_RS01775	COG4475	Protein of unknown function (DUF436)
AA105_RS01800	COG4221	oxidoreductase activity
AA105_RS01805	COG1902	pentaerythritol trinitrate reductase activity
AA105_RS01805	COG0446	pyridine nucleotide-disulphide oxidoreductase
AA105_RS01825	COG0544	peptidyl-prolyl cis-trans isomerase activity
AA105_RS01850	COG2801	Transposase and inactivated derivatives
AA105_RS01865	COG3343	RNA polymerase activity
AA105_RS01870	COG0504	CTP synthase activity
AA105_RS01880	COG0191	fructose-bisphosphate aldolase activity
AA105_RS01885	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AA105_RS01920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AA105_RS01950	COG0436	Aminotransferase
AA105_RS01955	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AA105_RS01960	COG1335	isochorismatase
AA105_RS01970	COG0335	large ribosomal subunit rRNA binding
AA105_RS01980	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AA105_RS01985	COG0154	amidase activity
AA105_RS01990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AA105_RS01995	COG1609	Transcriptional regulator
AA105_RS02000	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AA105_RS02005	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AA105_RS02020	COG3142	Participates in the control of copper homeostasis
AA105_RS02035	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AA105_RS02040	COG1534	Rna-binding protein
AA105_RS02045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AA105_RS02050	COG1713	HD superfamily hydrolase involved in NAD metabolism
AA105_RS02065	COG0799	negative regulation of ribosome biogenesis
AA105_RS02070	COG2226	methyltransferase
AA105_RS02085	COG0789	Transcriptional regulator
AA105_RS02095	COG0242	peptide deformylase activity
AA105_RS02105	COG1640	4-alpha-glucanotransferase
AA105_RS02110	COG0058	SHG alpha-glucan phosphorylase activity
AA105_RS02125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AA105_RS02125	COG1263	PTS System
AA105_RS02125	COG2190	(PTS) system
AA105_RS02140	COG0217	transcriptional regulatory protein
AA105_RS02150	COG4720	Psort location CytoplasmicMembrane, score
AA105_RS02160	COG1054	Belongs to the UPF0176 family
AA105_RS02170	COG1122	ATPase activity
AA105_RS02185	COG0357	Ribosomal RNA small subunit methyltransferase G
AA105_RS02190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AA105_RS02195	COG3331	DNA recombination
AA105_RS02200	COG4474	Belongs to the UPF0398 family
AA105_RS02205	COG3599	regulation of cell shape
AA105_RS02215	COG0116	Belongs to the methyltransferase superfamily
AA105_RS02225	COG1854	S-ribosylhomocysteine lyase activity
AA105_RS02230	COG1418	mRNA catabolic process
AA105_RS02240	COG1758	RNA polymerase activity
AA105_RS02245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AA105_RS02250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AA105_RS02255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AA105_RS02255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AA105_RS02260	COG0631	protein serine/threonine phosphatase activity
AA105_RS02265	COG0515	serine threonine protein kinase
AA105_RS02265	COG2815	serine threonine protein kinase
AA105_RS02290	COG1098	S1 RNA binding domain
AA105_RS02300	COG4974	Belongs to the 'phage' integrase family
AA105_RS02460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AA105_RS02465	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AA105_RS02470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AA105_RS02485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AA105_RS02490	COG3022	response to hydroperoxide
AA105_RS02500	COG3944	biosynthesis protein
AA105_RS02510	COG4464	protein tyrosine phosphatase activity
AA105_RS02525	COG0438	transferase activity, transferring glycosyl groups
AA105_RS02540	COG1216	Glycosyl transferase, family 2
AA105_RS02540	COG1442	glycosyl transferase family 8
AA105_RS02545	COG1442	glycosyl transferase family 8
AA105_RS02545	COG1216	Glycosyl transferase, family 2
AA105_RS02580	COG2089	acid synthase
AA105_RS02595	COG2755	lipolytic protein G-D-S-L family
AA105_RS02595	COG1083	cytidylyl-transferase
AA105_RS02675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AA105_RS02680	COG0077	Prephenate dehydratase
AA105_RS02690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AA105_RS02695	COG0562	UDP-galactopyranose mutase
AA105_RS02700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AA105_RS02715	COG0436	Aminotransferase
AA105_RS02735	COG0534	Mate efflux family protein
AA105_RS02740	COG0251	oxidation-reduction process
AA105_RS02745	COG1660	Displays ATPase and GTPase activities
AA105_RS02750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AA105_RS02755	COG1481	regulation of sporulation
AA105_RS02770	COG0454	-acetyltransferase
AA105_RS02775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AA105_RS02780	COG0549	Belongs to the carbamate kinase family
AA105_RS02785	COG1288	antiporter activity
AA105_RS02790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AA105_RS02795	COG3064	Membrane
AA105_RS02795	COG3583	domain protein
AA105_RS02795	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AA105_RS02800	COG1438	arginine binding
AA105_RS02805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AA105_RS02810	COG0363	glucosamine-6-phosphate deaminase activity
AA105_RS02840	COG1696	Membrane protein involved in D-alanine export
AA105_RS02845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AA105_RS02850	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AA105_RS02860	COG0435	Glutathione S-transferase
AA105_RS02865	COG1187	pseudouridine synthase activity
AA105_RS02870	COG0386	Belongs to the glutathione peroxidase family
AA105_RS02875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AA105_RS02880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AA105_RS02885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AA105_RS02890	COG1120	ATPase activity
AA105_RS02895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AA105_RS02900	COG0204	Acyl-transferase
AA105_RS02905	COG1555	photosystem II stabilization
AA105_RS02905	COG1596	polysaccharide export
AA105_RS02910	COG2333	competence protein COMEC
AA105_RS02910	COG0658	competence protein
AA105_RS02920	COG0517	IMP dehydrogenase activity
AA105_RS02935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AA105_RS02940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AA105_RS02945	COG0470	DNA polymerase III
AA105_RS02950	COG4467	Involved in initiation control of chromosome replication
AA105_RS02960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AA105_RS02970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AA105_RS02975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AA105_RS02980	COG1393	Belongs to the ArsC family
AA105_RS02990	COG0708	Exodeoxyribonuclease III
AA105_RS03000	COG0531	amino acid
AA105_RS03030	COG1061	Type III restriction enzyme res subunit
AA105_RS03035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AA105_RS03055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AA105_RS03060	COG4684	Psort location CytoplasmicMembrane, score
AA105_RS03065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AA105_RS03075	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AA105_RS03115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AA105_RS03120	COG1349	DNA-binding transcription factor activity
AA105_RS03130	COG1447	Phosphotransferase system cellobiose-specific component IIA
AA105_RS03135	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AA105_RS03140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AA105_RS03145	COG1882	Formate acetyltransferase
AA105_RS03165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AA105_RS03170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AA105_RS03180	COG1739	Uncharacterized protein family UPF0029
AA105_RS03185	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AA105_RS03265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AA105_RS03275	COG3557	Belongs to the UPF0374 family
AA105_RS03285	COG2188	Transcriptional regulator
AA105_RS03290	COG2188	Transcriptional regulator
AA105_RS03300	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AA105_RS03310	COG3716	PTS system mannose fructose sorbose family IID component
AA105_RS03320	COG2017	converts alpha-aldose to the beta-anomer
AA105_RS03335	COG0346	lactoylglutathione lyase activity
AA105_RS03370	COG0494	nUDIX hydrolase
AA105_RS03385	COG1217	gtp-binding protein TYPA
AA105_RS03400	COG0681	Belongs to the peptidase S26 family
AA105_RS03425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AA105_RS03440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AA105_RS03445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AA105_RS03450	COG1799	cell septum assembly
AA105_RS03465	COG3599	regulation of cell shape
AA105_RS03490	COG0494	nUDIX hydrolase
AA105_RS03490	COG0406	alpha-ribazole phosphatase activity
AA105_RS03495	COG0542	response to heat
AA105_RS03500	COG4703	Protein of unknown function (DUF1797)
AA105_RS03505	COG0765	amino acid transport
AA105_RS03515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AA105_RS03550	COG0789	Transcriptional regulator
AA105_RS03565	COG0826	peptidase U32
AA105_RS03575	COG4443	Transcriptional Coactivator p15 (PC4)
AA105_RS03580	COG1268	BioY protein
AA105_RS03590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AA105_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AA105_RS03610	COG1136	(ABC) transporter
AA105_RS03615	COG0577	efflux transmembrane transporter activity
AA105_RS03640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AA105_RS03650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AA105_RS03660	COG3859	Proton-coupled thiamine transporter YuaJ
AA105_RS03680	COG0772	Belongs to the SEDS family
AA105_RS03685	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AA105_RS03700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AA105_RS03705	COG0149	triose-phosphate isomerase activity
AA105_RS03715	COG1078	dGTPase activity
AA105_RS03750	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AA105_RS03755	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AA105_RS03760	COG2884	Cell division ATP-binding protein ftsE
AA105_RS03765	COG2177	Part of the ABC transporter FtsEX involved in
AA105_RS03785	COG1132	(ABC) transporter
AA105_RS03790	COG1132	(ABC) transporter
AA105_RS03795	COG1011	Hydrolase
AA105_RS03815	COG1737	Transcriptional regulator
AA105_RS03825	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AA105_RS03830	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AA105_RS03835	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AA105_RS03840	COG0237	dephospho-CoA kinase activity
AA105_RS03845	COG2814	Major facilitator Superfamily
AA105_RS03850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AA105_RS03860	COG0557	exoribonuclease II activity
AA105_RS03865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AA105_RS03870	COG1063	alcohol dehydrogenase
AA105_RS03885	COG2217	Heavy metal translocating P-type atpase
AA105_RS03890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AA105_RS03900	COG1136	(ABC) transporter
AA105_RS03910	COG3547	Transposase (IS116 IS110 IS902 family)
AA105_RS03930	COG0626	cystathionine gamma-synthase activity
AA105_RS03935	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AA105_RS03940	COG2207	Transcriptional regulator
AA105_RS03950	COG1653	transport
AA105_RS03955	COG1175	transmembrane transport
AA105_RS03960	COG0395	ABC-type sugar transport system, permease component
AA105_RS03970	COG0366	Alpha amylase catalytic
AA105_RS03975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AA105_RS03990	COG0683	leucine binding
AA105_RS04025	COG1466	dna polymerase III delta subunit
AA105_RS04030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AA105_RS04035	COG0737	Belongs to the 5'-nucleotidase family
AA105_RS04085	COG3561	AntA/AntB antirepressor
AA105_RS04320	COG0038	chloride channel
AA105_RS04325	COG0287	Prephenate dehydrogenase
AA105_RS04325	COG1605	Chorismate mutase
AA105_RS04335	COG0716	FMN binding
AA105_RS04340	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AA105_RS04360	COG1702	phosphate starvation-inducible protein PhoH
AA105_RS04370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AA105_RS04375	COG2807	transmembrane transport
AA105_RS04385	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AA105_RS04390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AA105_RS04400	COG1234	tRNA 3'-trailer cleavage
AA105_RS04405	COG0300	oxidoreductase activity
AA105_RS04415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AA105_RS04420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AA105_RS04420	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AA105_RS04430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AA105_RS04450	COG2384	SAM-dependent methyltransferase
AA105_RS04455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AA105_RS04465	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AA105_RS04480	COG1088	dTDP-glucose 4,6-dehydratase activity
AA105_RS04485	COG1091	dTDP-4-dehydrorhamnose reductase activity
AA105_RS04515	COG1216	Glycosyl transferase, family 2
AA105_RS04515	COG1442	glycosyl transferase family 8
AA105_RS04545	COG1442	glycosyl transferase family 8
AA105_RS04550	COG1216	Glycosyl transferase, family 2
AA105_RS04550	COG1442	glycosyl transferase family 8
AA105_RS04565	COG1216	Glycosyl transferase, family 2
AA105_RS04595	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AA105_RS04605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AA105_RS04620	COG1368	sulfuric ester hydrolase activity
AA105_RS04625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AA105_RS04630	COG0710	3-dehydroquinate dehydratase activity
AA105_RS04635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AA105_RS04640	COG0287	Prephenate dehydrogenase
AA105_RS04645	COG3679	Belongs to the UPF0342 family
AA105_RS04765	COG1164	Oligoendopeptidase f
AA105_RS04780	COG0210	DNA helicase
AA105_RS04790	COG1011	Hydrolase
AA105_RS04820	COG1131	(ABC) transporter
AA105_RS04850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AA105_RS04855	COG1074	ATP-dependent DNA helicase activity
AA105_RS04865	COG0187	DNA topoisomerase II activity
AA105_RS04870	COG2184	nucleotidyltransferase activity
AA105_RS04885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AA105_RS04895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AA105_RS04920	COG0539	negative regulation of cytoplasmic translation
AA105_RS04945	COG1104	cysteine desulfurase activity
AA105_RS04950	COG0301	tRNA thio-modification
AA105_RS04955	COG1114	Component of the transport system for branched-chain amino acids
AA105_RS04960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AA105_RS04965	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AA105_RS04985	COG0564	pseudouridine synthase activity
AA105_RS04990	COG2824	Alkylphosphonate utilization operon protein PhnA
AA105_RS05000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AA105_RS05005	COG0540	Belongs to the ATCase OTCase family
AA105_RS05010	COG0505	Belongs to the CarA family
AA105_RS05020	COG2521	methyltransferase
AA105_RS05020	COG2136	Putative SAM-dependent methyltransferase
AA105_RS05025	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AA105_RS05035	COG0228	four-way junction DNA binding
AA105_RS05050	COG1132	(ABC) transporter
AA105_RS05055	COG0726	polysaccharide deacetylase
AA105_RS05065	COG0083	homoserine kinase activity
AA105_RS05075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AA105_RS05080	COG3842	ATPase activity
AA105_RS05085	COG1176	ABC-type spermidine putrescine transport system, permease component I
AA105_RS05090	COG1177	transmembrane transport
AA105_RS05100	COG0038	chloride channel
AA105_RS05110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AA105_RS05115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AA105_RS05125	COG0534	Mate efflux family protein
AA105_RS05130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AA105_RS05135	COG0336	Belongs to the RNA methyltransferase TrmD family
AA105_RS05140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AA105_RS05145	COG1349	DNA-binding transcription factor activity
AA105_RS05150	COG1105	Belongs to the carbohydrate kinase PfkB family
AA105_RS05155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AA105_RS05155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AA105_RS05155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AA105_RS05165	COG1307	EDD domain protein, DegV family
AA105_RS05170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AA105_RS05175	COG0617	tRNA 3'-terminal CCA addition
AA105_RS05180	COG0488	(ABC) transporter
AA105_RS05190	COG1940	carbohydrate kinase activity
AA105_RS05205	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AA105_RS05210	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AA105_RS05220	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AA105_RS05235	COG0481	GTPase activity
AA105_RS05260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AA105_RS05265	COG2890	protein-(glutamine-N5) methyltransferase activity
AA105_RS05270	COG0009	L-threonylcarbamoyladenylate synthase
AA105_RS05280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AA105_RS05290	COG0741	lytic transglycosylase activity
AA105_RS05295	COG4221	oxidoreductase activity
AA105_RS05320	COG1401	restriction endodeoxyribonuclease activity
AA105_RS05325	COG4268	DNA restriction-modification system
AA105_RS05335	COG2188	Transcriptional regulator
AA105_RS05340	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AA105_RS05345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AA105_RS05360	COG1660	Displays ATPase and GTPase activities
AA105_RS05365	COG4974	Belongs to the 'phage' integrase family
AA105_RS05380	COG0745	RESPONSE REGULATOR receiver
AA105_RS05400	COG1136	(ABC) transporter
AA105_RS05430	COG2382	esterase
AA105_RS05440	COG3708	Transcriptional regulator
AA105_RS05440	COG2207	Transcriptional regulator
AA105_RS05445	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AA105_RS05450	COG0647	UMP catabolic process
AA105_RS05490	COG0395	ABC-type sugar transport system, permease component
AA105_RS05495	COG1175	transmembrane transport
AA105_RS05515	COG1070	Carbohydrate kinase
AA105_RS05530	COG3843	relaxase mobilization nuclease domain protein
AA105_RS05545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AA105_RS05565	COG0827	DNA restriction-modification system
AA105_RS05580	COG0270	DNA (cytosine-5-)-methyltransferase activity
AA105_RS05605	COG3942	CHAP domain
AA105_RS05605	COG1705	Flagellar rod assembly protein muramidase FlgJ
AA105_RS05665	COG4974	Belongs to the 'phage' integrase family
AA105_RS05675	COG1396	sequence-specific DNA binding
AA105_RS05695	COG1447	Phosphotransferase system cellobiose-specific component IIA
AA105_RS05705	COG1105	Belongs to the carbohydrate kinase PfkB family
AA105_RS05710	COG0698	ribose 5-phosphate isomerase
AA105_RS05715	COG0698	ribose 5-phosphate isomerase
AA105_RS05720	COG1940	carbohydrate kinase activity
AA105_RS05735	COG3843	relaxase mobilization nuclease domain protein
AA105_RS05755	COG0210	DNA helicase
AA105_RS05770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AA105_RS05775	COG0542	response to heat
AA105_RS05780	COG1396	sequence-specific DNA binding
AA105_RS05835	COG4443	Transcriptional Coactivator p15 (PC4)
AA105_RS05840	COG1475	DNA binding
AA105_RS06000	COG0270	DNA (cytosine-5-)-methyltransferase activity
AA105_RS06015	COG0222	ribosome binding
AA105_RS06020	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AA105_RS06025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AA105_RS06030	COG0758	DNA mediated transformation
AA105_RS06035	COG0110	maltose O-acetyltransferase activity
AA105_RS06040	COG1937	Protein conserved in bacteria
AA105_RS06050	COG0446	pyridine nucleotide-disulphide oxidoreductase
AA105_RS06060	COG1272	protein, Hemolysin III
AA105_RS06070	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AA105_RS06075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AA105_RS06085	COG0424	maF-like protein
AA105_RS06090	COG0737	Belongs to the 5'-nucleotidase family
AA105_RS06100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AA105_RS06105	COG0463	Glycosyl transferase, family 2
AA105_RS06115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AA105_RS06120	COG0284	orotidine-5'-phosphate decarboxylase activity
AA105_RS06125	COG0167	dihydroorotate dehydrogenase activity
AA105_RS06135	COG0583	DNA-binding transcription factor activity
AA105_RS06150	COG0297	glycogen (starch) synthase activity
AA105_RS06160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AA105_RS06165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AA105_RS06225	COG1126	abc transporter atp-binding protein
AA105_RS06235	COG0488	(ABC) transporter
AA105_RS06240	COG2873	o-acetylhomoserine
AA105_RS06265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AA105_RS06265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AA105_RS06275	COG3711	transcriptional antiterminator
AA105_RS06280	COG3684	Belongs to the aldolase LacD family
AA105_RS06285	COG1105	Belongs to the carbohydrate kinase PfkB family
AA105_RS06290	COG0698	ribose 5-phosphate isomerase
AA105_RS06295	COG0698	ribose 5-phosphate isomerase
AA105_RS06300	COG1349	DNA-binding transcription factor activity
AA105_RS06330	COG1396	sequence-specific DNA binding
AA105_RS06335	COG1194	a g-specific adenine glycosylase
AA105_RS06345	COG1132	(ABC) transporter
AA105_RS06350	COG1132	(ABC) transporter
AA105_RS06355	COG0280	phosphate acetyltransferase
AA105_RS06360	COG0564	pseudouridine synthase activity
AA105_RS06365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AA105_RS06370	COG2357	RelA SpoT domain protein
AA105_RS06375	COG4116	CYTH
AA105_RS06385	COG1104	cysteine desulfurase activity
AA105_RS06400	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AA105_RS06405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AA105_RS06415	COG3764	Sortase (surface protein transpeptidase)
AA105_RS06420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AA105_RS06425	COG0039	L-malate dehydrogenase activity
AA105_RS06430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AA105_RS06440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AA105_RS06445	COG1079	Belongs to the binding-protein-dependent transport system permease family
AA105_RS06450	COG4603	Belongs to the binding-protein-dependent transport system permease family
AA105_RS06455	COG3845	ABC transporter
AA105_RS06460	COG1744	ABC transporter substrate-binding protein PnrA-like
AA105_RS06475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AA105_RS06480	COG2813	Specifically methylates the guanine in position
AA105_RS06485	COG1072	(Pantothenic acid kinase))
AA105_RS06500	COG5002	protein histidine kinase activity
AA105_RS06505	COG0745	RESPONSE REGULATOR receiver
AA105_RS06520	COG0704	Plays a role in the regulation of phosphate uptake
AA105_RS06525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AA105_RS06530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AA105_RS06535	COG0581	inorganic phosphate transmembrane transporter activity
AA105_RS06540	COG0573	inorganic phosphate transmembrane transporter activity
AA105_RS06550	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AA105_RS06550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AA105_RS06555	COG0483	inositol monophosphate 1-phosphatase activity
AA105_RS06560	COG4476	Belongs to the UPF0223 family
AA105_RS06565	COG1393	Belongs to the ArsC family
AA105_RS06570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AA105_RS06575	COG0196	riboflavin kinase activity
AA105_RS06580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AA105_RS06620	COG0561	phosphatase activity
AA105_RS06625	COG2195	Cleaves the N-terminal amino acid of tripeptides
AA105_RS06640	COG1695	Transcriptional regulator
AA105_RS06660	COG3759	membrane
AA105_RS06665	COG1846	Transcriptional regulator
AA105_RS06680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AA105_RS06685	COG2610	gluconate transmembrane transporter activity
AA105_RS06705	COG0302	gtp cyclohydrolase
AA105_RS06710	COG1051	belongs to the nudix hydrolase family
AA105_RS06735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AA105_RS06735	COG0072	phenylalanine-tRNA ligase activity
AA105_RS06765	COG1028	Short-chain dehydrogenase reductase Sdr
AA105_RS06770	COG1312	Catalyzes the dehydration of D-mannonate
AA105_RS06780	COG0800	Aldolase
AA105_RS06790	COG3250	beta-galactosidase activity
AA105_RS06800	COG2211	Major facilitator Superfamily
AA105_RS06815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AA105_RS06825	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AA105_RS06830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AA105_RS06835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AA105_RS06840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AA105_RS06845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AA105_RS06850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AA105_RS06855	COG0356	it plays a direct role in the translocation of protons across the membrane
AA105_RS06865	COG1597	lipid kinase activity
AA105_RS06875	COG0701	Predicted permease
AA105_RS06880	COG3689	TIGRFAM TIGR03943 family protein
AA105_RS06885	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AA105_RS06900	COG0552	protein localization to endoplasmic reticulum
AA105_RS06905	COG0561	phosphatase activity
AA105_RS06910	COG0561	phosphatase activity
AA105_RS06915	COG1196	nuclear chromosome segregation
AA105_RS06950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AA105_RS06955	COG0538	isocitrate dehydrogenase activity
AA105_RS06960	COG0372	Belongs to the citrate synthase family
AA105_RS06965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AA105_RS06970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AA105_RS06975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AA105_RS06980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AA105_RS06985	COG1609	Transcriptional regulator
AA105_RS07000	COG5492	domain, Protein
AA105_RS07010	COG3716	PTS system mannose fructose sorbose family IID component
AA105_RS07020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AA105_RS07025	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AA105_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
AA105_RS07085	COG1476	TRANSCRIPTIONal
AA105_RS07105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AA105_RS07115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AA105_RS07120	COG4122	O-methyltransferase activity
AA105_RS07145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AA105_RS07145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AA105_RS07155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AA105_RS07160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AA105_RS07165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AA105_RS07170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AA105_RS07175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AA105_RS07175	COG1116	anion transmembrane transporter activity
AA105_RS07180	COG4120	Belongs to the binding-protein-dependent transport system permease family
AA105_RS07200	COG3684	Belongs to the aldolase LacD family
AA105_RS07215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AA105_RS07220	COG1126	abc transporter atp-binding protein
AA105_RS07225	COG0765	amino acid transport
AA105_RS07230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AA105_RS07245	COG2755	lipolytic protein G-D-S-L family
AA105_RS07245	COG0657	acetylesterase activity
AA105_RS07250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AA105_RS07260	COG0469	pyruvate kinase activity
AA105_RS07265	COG0205	6-phosphofructokinase activity
AA105_RS07275	COG2188	Transcriptional regulator
AA105_RS07280	COG1131	(ABC) transporter
AA105_RS07290	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AA105_RS07315	COG2151	metal-sulfur cluster biosynthetic enzyme
AA105_RS07320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AA105_RS07325	COG0358	DNA primase activity
AA105_RS07330	COG1970	mechanosensitive ion channel activity
AA105_RS07335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AA105_RS07340	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AA105_RS07350	COG0647	UMP catabolic process
AA105_RS07355	COG1051	belongs to the nudix hydrolase family
AA105_RS07365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AA105_RS07375	COG0058	SHG alpha-glucan phosphorylase activity
AA105_RS07380	COG0813	purine-nucleoside phosphorylase activity
AA105_RS07385	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AA105_RS07395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AA105_RS07400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AA105_RS07415	COG1518	maintenance of DNA repeat elements
AA105_RS07425	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AA105_RS07440	COG2268	Band 7 protein
AA105_RS07445	COG1704	LemA family
AA105_RS07455	COG1573	uracil-dna glycosylase
AA105_RS07475	COG2226	methyltransferase
AA105_RS07480	COG0488	(ABC) transporter
AA105_RS07485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AA105_RS07500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AA105_RS07505	COG3442	glutamine amidotransferase
AA105_RS07510	COG2226	methyltransferase
AA105_RS07520	COG0488	(ABC) transporter
AA105_RS07555	COG3842	ATPase activity
AA105_RS07575	COG1263	PTS System
AA105_RS07575	COG2190	(PTS) system
AA105_RS07575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AA105_RS07580	COG3711	transcriptional antiterminator
AA105_RS07585	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AA105_RS07590	COG3527	Alpha-acetolactate decarboxylase
AA105_RS07600	COG0628	permease
AA105_RS07605	COG2706	6-phosphogluconolactonase activity
AA105_RS07615	COG1011	Hydrolase
AA105_RS07735	COG0560	Phosphoserine phosphatase
AA105_RS07740	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AA105_RS07745	COG0187	DNA topoisomerase II activity
AA105_RS07750	COG0693	protein deglycase activity
AA105_RS07755	COG0772	Belongs to the SEDS family
AA105_RS07765	COG4479	Belongs to the UPF0346 family
AA105_RS07780	COG2996	Protein conserved in bacteria
AA105_RS07785	COG0233	cytoplasmic translational termination
AA105_RS07790	COG0528	UMP kinase activity
AA105_RS07795	COG2244	polysaccharide biosynthetic process
AA105_RS07800	COG0625	glutathione transferase activity
AA105_RS07825	COG0346	lactoylglutathione lyase activity
AA105_RS07830	COG0697	spore germination
AA105_RS07830	COG1674	ftsk spoiiie
AA105_RS07835	COG1621	beta-fructofuranosidase activity
AA105_RS07840	COG1653	transport
AA105_RS07845	COG0395	ABC-type sugar transport system, permease component
AA105_RS07850	COG4209	transmembrane transport
AA105_RS07855	COG1609	Transcriptional regulator
AA105_RS07875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AA105_RS07890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AA105_RS07900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AA105_RS07920	COG1181	Belongs to the D-alanine--D-alanine ligase family
AA105_RS07925	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AA105_RS07930	COG0768	penicillin binding
AA105_RS07935	COG0488	(ABC) transporter
AA105_RS07950	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AA105_RS07960	COG0745	RESPONSE REGULATOR receiver
AA105_RS07970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AA105_RS07975	COG0765	amino acid transport
AA105_RS07980	COG0765	amino acid transport
AA105_RS07985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AA105_RS08000	COG0438	transferase activity, transferring glycosyl groups
AA105_RS08015	COG1609	Transcriptional regulator
AA105_RS08025	COG0343	queuine tRNA-ribosyltransferase activity
AA105_RS08035	COG1832	CoA-binding protein
AA105_RS08045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AA105_RS08045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AA105_RS08055	COG3547	Transposase (IS116 IS110 IS902 family)
AA105_RS08060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AA105_RS08065	COG2827	Endonuclease containing a URI domain
AA105_RS08085	COG0640	Transcriptional regulator
AA105_RS08090	COG0513	Belongs to the DEAD box helicase family
AA105_RS08095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AA105_RS08140	COG0494	nUDIX hydrolase
AA105_RS08145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AA105_RS08155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AA105_RS08160	COG1028	Short-chain dehydrogenase reductase Sdr
AA105_RS08185	COG0577	efflux transmembrane transporter activity
AA105_RS08190	COG1136	(ABC) transporter
AA105_RS08195	COG2205	protein histidine kinase activity
AA105_RS08210	COG0436	Aminotransferase
AA105_RS08220	COG1174	glycine betaine transport
AA105_RS08225	COG0517	IMP dehydrogenase activity
AA105_RS08225	COG1125	glycine betaine transport
AA105_RS08245	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AA105_RS08250	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AA105_RS08255	COG1482	cell wall glycoprotein biosynthetic process
AA105_RS08270	COG3091	SprT-like family
AA105_RS08275	COG2183	response to ionizing radiation
AA105_RS08295	COG0656	L-ascorbic acid biosynthetic process
AA105_RS08300	COG4708	membrane
AA105_RS08305	COG2246	polysaccharide biosynthetic process
AA105_RS08315	COG0024	Methionine aminopeptidase
AA105_RS08325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AA105_RS08330	COG2249	NAD(P)H dehydrogenase (quinone) activity
AA105_RS08335	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AA105_RS08345	COG2131	deaminase
AA105_RS08365	COG1363	Peptidase, m42
AA105_RS08380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AA105_RS08385	COG1956	GAF domain-containing protein
AA105_RS08405	COG0673	inositol 2-dehydrogenase activity
AA105_RS08410	COG0513	Belongs to the DEAD box helicase family
AA105_RS08415	COG0726	polysaccharide deacetylase
AA105_RS08430	COG0183	Belongs to the thiolase family
AA105_RS08435	COG3425	synthase
AA105_RS08460	COG0776	regulation of translation
AA105_RS08470	COG2755	lipolytic protein G-D-S-L family
AA105_RS08475	COG1307	EDD domain protein, DegV family
AA105_RS08480	COG0497	DNA recombination
AA105_RS08485	COG1438	arginine binding
AA105_RS08490	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AA105_RS08500	COG1722	exodeoxyribonuclease VII activity
AA105_RS08505	COG1570	exodeoxyribonuclease VII activity
AA105_RS08510	COG2321	neutral zinc metallopeptidase
AA105_RS08515	COG1755	Isoprenylcysteine carboxyl methyltransferase
AA105_RS08520	COG5002	protein histidine kinase activity
AA105_RS08525	COG0745	RESPONSE REGULATOR receiver
AA105_RS08545	COG1227	inorganic diphosphatase activity
AA105_RS08555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AA105_RS08560	COG1253	flavin adenine dinucleotide binding
AA105_RS08565	COG1119	ATPase activity
AA105_RS08570	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AA105_RS08580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AA105_RS08585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AA105_RS08600	COG4470	Protein conserved in bacteria
AA105_RS08605	COG3480	Lon protease (S16) C-terminal proteolytic domain
AA105_RS08610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AA105_RS08615	COG0742	ribosomal rna small subunit methyltransferase
AA105_RS08625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AA105_RS08630	COG4483	Protein conserved in bacteria
AA105_RS08635	COG2197	response regulator
AA105_RS08640	COG2203	Gaf domain
AA105_RS08640	COG4585	Histidine kinase
AA105_RS08645	COG0842	Transport permease protein
AA105_RS08650	COG1131	(ABC) transporter
AA105_RS08665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AA105_RS08675	COG2755	lipolytic protein G-D-S-L family
AA105_RS08675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AA105_RS08680	COG0671	phosphoesterase, PA-phosphatase related
AA105_RS08685	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AA105_RS08700	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AA105_RS08705	COG1187	pseudouridine synthase activity
AA105_RS08710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AA105_RS08715	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AA105_RS08720	COG0582	viral genome integration into host DNA
AA105_RS08740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AA105_RS08745	COG3763	UPF0154 protein
AA105_RS08755	COG3579	cysteine-type endopeptidase activity
AA105_RS08770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AA105_RS08775	COG1254	Belongs to the acylphosphatase family
AA105_RS08785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AA105_RS08790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AA105_RS08800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AA105_RS08810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AA105_RS08825	COG1160	GTP binding
AA105_RS08835	COG1484	DNA-dependent DNA replication
AA105_RS08845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AA105_RS08850	COG0628	permease
AA105_RS08855	COG0745	RESPONSE REGULATOR receiver
AA105_RS08860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AA105_RS08870	COG0492	ferredoxin-NADP+ reductase activity
AA105_RS08880	COG0513	Belongs to the DEAD box helicase family
AA105_RS08900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AA105_RS08905	COG0768	penicillin binding
AA105_RS08915	COG0275	rRNA processing
AA105_RS08975	COG4939	FMN-binding domain protein
AA105_RS08980	COG0142	geranyltranstransferase activity
AA105_RS08985	COG1252	NADH dehydrogenase
AA105_RS09000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AA105_RS09005	COG0569	domain protein
AA105_RS09010	COG0534	Mate efflux family protein
AA105_RS09020	COG4224	UPF0291 protein
AA105_RS09025	COG0751	glycine-tRNA ligase activity
AA105_RS09050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AA105_RS09055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AA105_RS09060	COG1464	Belongs to the NlpA lipoprotein family
AA105_RS09065	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AA105_RS09070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AA105_RS09075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AA105_RS09085	COG0561	phosphatase activity
AA105_RS09095	COG3715	PTS system
AA105_RS09100	COG3716	PTS system mannose fructose sorbose family IID component
AA105_RS09130	COG3177	Filamentation induced by cAMP protein fic
AA105_RS09140	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AA105_RS09175	COG0825	malonyl-CoA metabolic process
AA105_RS09185	COG0439	Biotin carboxylase
AA105_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
AA105_RS09210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AA105_RS09215	COG2070	2-Nitropropane dioxygenase
AA105_RS09225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AA105_RS09235	COG1024	Enoyl-CoA hydratase
AA105_RS09240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AA105_RS09245	COG0527	aspartate kinase activity
AA105_RS09255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AA105_RS09260	COG0736	holo-[acyl-carrier-protein] synthase activity
AA105_RS09265	COG0653	protein targeting
AA105_RS09275	COG1940	carbohydrate kinase activity
AA105_RS09280	COG2190	(PTS) system
AA105_RS09280	COG1263	PTS System
AA105_RS09280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AA105_RS09285	COG1621	beta-fructofuranosidase activity
AA105_RS09290	COG1609	Transcriptional regulator
AA105_RS09295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AA105_RS09310	COG0006	proline dipeptidase activity
AA105_RS09315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AA105_RS09330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AA105_RS09335	COG0629	single-stranded DNA binding
AA105_RS09345	COG0095	Lipoate-protein ligase
AA105_RS09350	COG2723	6-phospho-beta-galactosidase activity
AA105_RS09365	COG2723	6-phospho-beta-galactosidase activity
AA105_RS09380	COG1447	Phosphotransferase system cellobiose-specific component IIA
AA105_RS09385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AA105_RS09385	COG3711	transcriptional antiterminator
AA105_RS09400	COG4095	Psort location CytoplasmicMembrane, score
AA105_RS09405	COG2723	6-phospho-beta-galactosidase activity
AA105_RS09410	COG0346	lactoylglutathione lyase activity
AA105_RS09415	COG2723	6-phospho-beta-galactosidase activity
AA105_RS09420	COG1917	Cupin 2, conserved barrel domain protein
AA105_RS09420	COG2207	Transcriptional regulator
AA105_RS09430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AA105_RS09430	COG1263	PTS System
AA105_RS09430	COG2190	(PTS) system
AA105_RS09435	COG3711	transcriptional antiterminator
AA105_RS09450	COG0508	dehydrogenase complex catalyzes the overall conversion of
AA105_RS09455	COG0508	dehydrogenase complex catalyzes the overall conversion of
AA105_RS09455	COG0022	dehydrogenase e1 component
AA105_RS09460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AA105_RS09465	COG2860	membrane
AA105_RS09480	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AA105_RS09485	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AA105_RS09495	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AA105_RS09500	COG0195	Participates in both transcription termination and antitermination
AA105_RS09510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AA105_RS09520	COG4473	ABC transporter
AA105_RS09525	COG1131	(ABC) transporter
AA105_RS09530	COG0537	adenosine 5'-monophosphoramidase activity
AA105_RS09540	COG1316	TRANSCRIPTIONal
AA105_RS09550	COG0802	atpase or kinase
AA105_RS09570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AA105_RS09575	COG0601	transmembrane transport
AA105_RS09580	COG4608	Belongs to the ABC transporter superfamily
AA105_RS09590	COG0747	negative chemotaxis
AA105_RS09595	COG1686	Belongs to the peptidase S11 family
AA105_RS09610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AA105_RS09615	COG0719	Fe-S assembly protein
AA105_RS09630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AA105_RS09635	COG4862	establishment of competence for transformation
AA105_RS09640	COG1968	undecaprenyl-diphosphatase activity
AA105_RS09645	COG0765	amino acid transport
AA105_RS09650	COG1126	abc transporter atp-binding protein
AA105_RS09665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AA105_RS09670	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AA105_RS09675	COG0440	acetolactate synthase activity
AA105_RS09680	COG0028	Belongs to the TPP enzyme family
AA105_RS09685	COG0463	Glycosyl transferase, family 2
AA105_RS09700	COG0129	dihydroxy-acid dehydratase activity
AA105_RS09710	COG2151	metal-sulfur cluster biosynthetic enzyme
AA105_RS09770	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AA105_RS09825	COG0789	Transcriptional regulator
AA105_RS09825	COG4978	Transcriptional regulator
AA105_RS09865	COG0582	viral genome integration into host DNA
AA105_RS09875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AA105_RS09890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AA105_RS09905	COG3842	ATPase activity
AA105_RS09915	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AA105_RS09935	COG1045	serine acetyltransferase
AA105_RS09940	COG1185	polyribonucleotide nucleotidyltransferase activity
AA105_RS09945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AA105_RS09950	COG1131	(ABC) transporter
AA105_RS09990	COG2801	Transposase and inactivated derivatives
AA105_RS10000	COG1187	pseudouridine synthase activity
AA105_RS10015	COG0242	peptide deformylase activity
AA105_RS10025	COG0066	3-isopropylmalate dehydratase activity
AA105_RS10045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AA105_RS10055	COG2188	Transcriptional regulator
AA105_RS10060	COG1447	Phosphotransferase system cellobiose-specific component IIA
AA105_RS10075	COG2309	aminopeptidase activity
AA105_RS10095	COG2176	DNA-directed DNA polymerase activity
AA105_RS10100	COG2376	Dihydroxyacetone kinase
AA105_RS10110	COG2376	Dihydroxyacetone kinase
AA105_RS10115	COG1461	Dihydroxyacetone kinase
AA105_RS10120	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AA105_RS10125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AA105_RS10130	COG0442	prolyl-tRNA aminoacylation
AA105_RS10140	COG4589	Belongs to the CDS family
AA105_RS10145	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AA105_RS10150	COG1862	Preprotein translocase
AA105_RS10160	COG1181	Belongs to the D-alanine--D-alanine ligase family
AA105_RS10160	COG2918	glutathione biosynthetic process
AA105_RS10170	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AA105_RS10175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AA105_RS10180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AA105_RS10185	COG0542	response to heat
AA105_RS10190	COG4463	regulation of RNA biosynthetic process
AA105_RS10200	COG1388	LysM domain
AA105_RS10200	COG4932	domain protein
AA105_RS10210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AA105_RS10245	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AA105_RS10250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AA105_RS10255	COG0492	ferredoxin-NADP+ reductase activity
AA105_RS10260	COG0564	pseudouridine synthase activity
AA105_RS10395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AA105_RS10415	COG1564	THIamine pyrophosphokinase
AA105_RS10425	COG1162	GTPase activity
AA105_RS10435	COG1132	(ABC) transporter
AA105_RS10460	COG4115	mRNA cleavage
AA105_RS10485	COG0084	hydrolase, TatD family'
AA105_RS10495	COG1847	R3H domain protein
AA105_RS10505	COG0594	ribonuclease P activity
AA105_RS10510	COG0165	Argininosuccinate lyase
AA105_RS10515	COG0137	argininosuccinate synthase activity
AA105_RS10525	COG1827	regulation of RNA biosynthetic process
AA105_RS10580	COG0756	dUTP diphosphatase activity
AA105_RS10585	COG0582	viral genome integration into host DNA
AA105_RS10660	COG1132	(ABC) transporter
AA105_RS10665	COG1132	(ABC) transporter
AA105_RS10675	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AA105_RS10680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AA105_RS10685	COG0705	Rhomboid family
AA105_RS10690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AA105_RS10695	COG1473	amidohydrolase
AA105_RS10700	COG2171	N-acyltransferase activity
AA105_RS10710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AA105_RS10730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AA105_RS10755	COG3623	hexulose-6-phosphate isomerase
AA105_RS10780	COG1523	belongs to the glycosyl hydrolase 13 family
AA105_RS10785	COG1609	Transcriptional regulator
AA105_RS10790	COG1126	abc transporter atp-binding protein
AA105_RS10795	COG0765	amino acid transport
AA105_RS10800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AA105_RS10805	COG3942	CHAP domain
AA105_RS10810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AA105_RS10820	COG1447	Phosphotransferase system cellobiose-specific component IIA
AA105_RS10830	COG3711	transcriptional antiterminator
AA105_RS10830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AA105_RS10840	COG2723	6-phospho-beta-galactosidase activity
AA105_RS10845	COG1486	melibiose metabolic process
AA105_RS10855	COG3590	peptidase
AA105_RS10860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AA105_RS10865	COG1321	iron dependent repressor
AA105_RS10865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AA105_RS10870	COG1121	(ABC) transporter
AA105_RS10880	COG0803	Belongs to the bacterial solute-binding protein 9 family
AA105_RS10900	COG1490	D-aminoacyl-tRNA deacylase activity
AA105_RS10910	COG0737	Belongs to the 5'-nucleotidase family
AA105_RS10930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AA105_RS10950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AA105_RS10975	COG0737	Belongs to the 5'-nucleotidase family
AA105_RS10985	COG1328	CTP reductase activity
AA105_RS10990	COG1126	abc transporter atp-binding protein
AA105_RS11000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AA105_RS11005	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AA105_RS11020	COG1438	arginine binding
AA105_RS11025	COG0018	arginyl-trna synthetase
AA105_RS11045	COG1640	4-alpha-glucanotransferase
AA105_RS11050	COG2182	Extracellular solute-binding protein
AA105_RS11055	COG1175	transmembrane transport
AA105_RS11060	COG3833	ABC-type maltose transport systems, permease component
AA105_RS11065	COG5521	maltodextrose utilization protein MalA
AA105_RS11070	COG1609	Transcriptional regulator
AA105_RS11075	COG1523	belongs to the glycosyl hydrolase 13 family
AA105_RS11080	COG1780	Probably involved in ribonucleotide reductase function
AA105_RS11085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AA105_RS11090	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AA105_RS11095	COG2153	protein acetylation
AA105_RS11100	COG4989	oxidoreductase activity
AA105_RS11105	COG1216	Glycosyl transferase, family 2
AA105_RS11125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AA105_RS11135	COG0305	Participates in initiation and elongation during chromosome replication
AA105_RS11140	COG0359	binds to the 23S rRNA
AA105_RS11150	COG0445	tRNA wobble uridine modification
AA105_RS11155	COG0494	nUDIX hydrolase
AA105_RS11160	COG1733	regulation of RNA biosynthetic process
AA105_RS11170	COG0482	sulfurtransferase activity
AA105_RS11175	COG1760	l-serine dehydratase
AA105_RS11180	COG1760	l-serine dehydratase
AA105_RS11190	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AA105_RS11195	COG1122	ATPase activity
AA105_RS11200	COG1122	ATPase activity
AA105_RS11205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AA105_RS11210	COG1426	Protein conserved in bacteria
AA105_RS11215	COG0612	Peptidase, M16
AA105_RS11220	COG0612	Peptidase, M16
AA105_RS11300	COG0582	viral genome integration into host DNA
AA105_RS11310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AA105_RS11320	COG0517	IMP dehydrogenase activity
AA105_RS11320	COG0516	GMP reductase activity
AA105_RS11330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AA105_RS11335	COG0488	(ABC) transporter
AA105_RS11365	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AA105_RS11370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain