locus-tag	class	description
APQ97_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APQ97_RS00015	COG0592	DNA-directed DNA polymerase activity
APQ97_RS00035	COG0012	GTP binding
APQ97_RS00040	COG0193	aminoacyl-tRNA hydrolase activity
APQ97_RS00045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APQ97_RS00050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
APQ97_RS00070	COG0037	tRNA processing
APQ97_RS00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APQ97_RS00155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APQ97_RS00165	COG3557	Belongs to the UPF0374 family
APQ97_RS00175	COG2188	Transcriptional regulator
APQ97_RS00180	COG2188	Transcriptional regulator
APQ97_RS00190	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APQ97_RS00200	COG3716	PTS system mannose fructose sorbose family IID component
APQ97_RS00210	COG2017	converts alpha-aldose to the beta-anomer
APQ97_RS00225	COG0346	lactoylglutathione lyase activity
APQ97_RS00260	COG0494	nUDIX hydrolase
APQ97_RS00275	COG1217	gtp-binding protein TYPA
APQ97_RS00290	COG0681	Belongs to the peptidase S26 family
APQ97_RS00305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APQ97_RS00310	COG0632	four-way junction helicase activity
APQ97_RS00315	COG0519	Catalyzes the synthesis of GMP from XMP
APQ97_RS00330	COG1393	Belongs to the ArsC family
APQ97_RS00335	COG4472	Bacterial protein of unknown function (DUF965)
APQ97_RS00340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APQ97_RS00345	COG3906	Belongs to the UPF0473 family
APQ97_RS00360	COG0051	transcription antitermination factor activity, RNA binding
APQ97_RS00365	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APQ97_RS00370	COG0088	Forms part of the polypeptide exit tunnel
APQ97_RS00375	COG0089	rRNA binding
APQ97_RS00380	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APQ97_RS00385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APQ97_RS00390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APQ97_RS00395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APQ97_RS00400	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APQ97_RS00405	COG0255	Belongs to the universal ribosomal protein uL29 family
APQ97_RS00410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APQ97_RS00415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APQ97_RS00420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APQ97_RS00425	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APQ97_RS00430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APQ97_RS00440	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APQ97_RS00450	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APQ97_RS00455	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APQ97_RS00460	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APQ97_RS00465	COG1841	ribosomal large subunit assembly
APQ97_RS00475	COG0201	protein transport
APQ97_RS00480	COG0563	adenylate kinase activity
APQ97_RS00485	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APQ97_RS00490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
APQ97_RS00495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APQ97_RS00505	COG0202	RNA polymerase activity
APQ97_RS00635	COG1792	Involved in formation and maintenance of cell shape
APQ97_RS00650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APQ97_RS00655	COG0436	Aminotransferase
APQ97_RS00660	COG1381	Involved in DNA repair and RecF pathway recombination
APQ97_RS00665	COG0416	fatty acid biosynthetic process
APQ97_RS00670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APQ97_RS00680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APQ97_RS00695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APQ97_RS00700	COG0138	bifunctional purine biosynthesis protein purh
APQ97_RS00725	COG0151	Belongs to the GarS family
APQ97_RS00730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APQ97_RS00745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APQ97_RS00775	COG1131	(ABC) transporter
APQ97_RS00785	COG1132	(ABC) transporter
APQ97_RS00790	COG2255	four-way junction helicase activity
APQ97_RS00800	COG0546	phosphoglycolate phosphatase activity
APQ97_RS00820	COG1126	abc transporter atp-binding protein
APQ97_RS00825	COG1328	CTP reductase activity
APQ97_RS00835	COG0737	Belongs to the 5'-nucleotidase family
APQ97_RS00865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
APQ97_RS00885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
APQ97_RS00920	COG1490	D-aminoacyl-tRNA deacylase activity
APQ97_RS00940	COG0803	Belongs to the bacterial solute-binding protein 9 family
APQ97_RS00950	COG1121	(ABC) transporter
APQ97_RS00955	COG1321	iron dependent repressor
APQ97_RS00955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
APQ97_RS00960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
APQ97_RS00965	COG3590	peptidase
APQ97_RS00975	COG1486	melibiose metabolic process
APQ97_RS00980	COG2723	6-phospho-beta-galactosidase activity
APQ97_RS00990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APQ97_RS00990	COG3711	transcriptional antiterminator
APQ97_RS01000	COG1447	Phosphotransferase system cellobiose-specific component IIA
APQ97_RS01010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APQ97_RS01015	COG3942	CHAP domain
APQ97_RS01020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APQ97_RS01025	COG0765	amino acid transport
APQ97_RS01030	COG1126	abc transporter atp-binding protein
APQ97_RS01035	COG1609	Transcriptional regulator
APQ97_RS01040	COG1523	belongs to the glycosyl hydrolase 13 family
APQ97_RS01065	COG3623	hexulose-6-phosphate isomerase
APQ97_RS01090	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APQ97_RS01115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
APQ97_RS01125	COG2171	N-acyltransferase activity
APQ97_RS01130	COG1473	amidohydrolase
APQ97_RS01135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APQ97_RS01140	COG0705	Rhomboid family
APQ97_RS01145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
APQ97_RS01150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
APQ97_RS01160	COG1132	(ABC) transporter
APQ97_RS01165	COG1132	(ABC) transporter
APQ97_RS01170	COG0756	dUTP diphosphatase activity
APQ97_RS01225	COG1827	regulation of RNA biosynthetic process
APQ97_RS01235	COG0137	argininosuccinate synthase activity
APQ97_RS01240	COG0165	Argininosuccinate lyase
APQ97_RS01245	COG0594	ribonuclease P activity
APQ97_RS01255	COG1847	R3H domain protein
APQ97_RS01265	COG0084	hydrolase, TatD family'
APQ97_RS01290	COG4115	mRNA cleavage
APQ97_RS01325	COG1132	(ABC) transporter
APQ97_RS01330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
APQ97_RS01345	COG1162	GTPase activity
APQ97_RS01355	COG1564	THIamine pyrophosphokinase
APQ97_RS01375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APQ97_RS01415	COG0564	pseudouridine synthase activity
APQ97_RS01420	COG0492	ferredoxin-NADP+ reductase activity
APQ97_RS01425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
APQ97_RS01430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
APQ97_RS01470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APQ97_RS01485	COG4463	regulation of RNA biosynthetic process
APQ97_RS01490	COG0542	response to heat
APQ97_RS01495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APQ97_RS01515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APQ97_RS01520	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APQ97_RS01530	COG1181	Belongs to the D-alanine--D-alanine ligase family
APQ97_RS01530	COG2918	glutathione biosynthetic process
APQ97_RS01540	COG1862	Preprotein translocase
APQ97_RS01545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APQ97_RS01550	COG4589	Belongs to the CDS family
APQ97_RS01560	COG0442	prolyl-tRNA aminoacylation
APQ97_RS01565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
APQ97_RS01570	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
APQ97_RS01575	COG1461	Dihydroxyacetone kinase
APQ97_RS01580	COG2376	Dihydroxyacetone kinase
APQ97_RS01590	COG2376	Dihydroxyacetone kinase
APQ97_RS01595	COG2176	DNA-directed DNA polymerase activity
APQ97_RS01610	COG2309	aminopeptidase activity
APQ97_RS01635	COG0066	3-isopropylmalate dehydratase activity
APQ97_RS01645	COG0242	peptide deformylase activity
APQ97_RS01660	COG1187	pseudouridine synthase activity
APQ97_RS01670	COG2801	Transposase and inactivated derivatives
APQ97_RS01715	COG1131	(ABC) transporter
APQ97_RS01720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APQ97_RS01725	COG1185	polyribonucleotide nucleotidyltransferase activity
APQ97_RS01730	COG1045	serine acetyltransferase
APQ97_RS01750	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APQ97_RS01760	COG3842	ATPase activity
APQ97_RS01775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APQ97_RS01790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APQ97_RS01850	COG2151	metal-sulfur cluster biosynthetic enzyme
APQ97_RS01865	COG0129	dihydroxy-acid dehydratase activity
APQ97_RS01880	COG0463	Glycosyl transferase, family 2
APQ97_RS01885	COG0028	Belongs to the TPP enzyme family
APQ97_RS01890	COG0440	acetolactate synthase activity
APQ97_RS01895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
APQ97_RS01900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
APQ97_RS01920	COG0765	amino acid transport
APQ97_RS01925	COG1968	undecaprenyl-diphosphatase activity
APQ97_RS01930	COG4862	establishment of competence for transformation
APQ97_RS01935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APQ97_RS01950	COG0719	Fe-S assembly protein
APQ97_RS01955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APQ97_RS01970	COG1686	Belongs to the peptidase S11 family
APQ97_RS01975	COG0747	negative chemotaxis
APQ97_RS01985	COG4608	Belongs to the ABC transporter superfamily
APQ97_RS01990	COG0601	transmembrane transport
APQ97_RS01995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
APQ97_RS02015	COG0802	atpase or kinase
APQ97_RS02025	COG1316	TRANSCRIPTIONal
APQ97_RS02035	COG0537	adenosine 5'-monophosphoramidase activity
APQ97_RS02040	COG1131	(ABC) transporter
APQ97_RS02045	COG4473	ABC transporter
APQ97_RS02055	COG0220	tRNA (guanine-N7-)-methyltransferase activity
APQ97_RS02065	COG0195	Participates in both transcription termination and antitermination
APQ97_RS02070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
APQ97_RS02080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APQ97_RS02085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APQ97_RS02100	COG2860	membrane
APQ97_RS02105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
APQ97_RS02110	COG0022	dehydrogenase e1 component
APQ97_RS02110	COG0508	dehydrogenase complex catalyzes the overall conversion of
APQ97_RS02115	COG0508	dehydrogenase complex catalyzes the overall conversion of
APQ97_RS02130	COG3711	transcriptional antiterminator
APQ97_RS02135	COG2190	(PTS) system
APQ97_RS02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APQ97_RS02135	COG1263	PTS System
APQ97_RS02150	COG2207	Transcriptional regulator
APQ97_RS02155	COG2723	6-phospho-beta-galactosidase activity
APQ97_RS02160	COG0346	lactoylglutathione lyase activity
APQ97_RS02165	COG2723	6-phospho-beta-galactosidase activity
APQ97_RS02170	COG4095	Psort location CytoplasmicMembrane, score
APQ97_RS02185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APQ97_RS02185	COG3711	transcriptional antiterminator
APQ97_RS02190	COG1447	Phosphotransferase system cellobiose-specific component IIA
APQ97_RS02200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APQ97_RS02205	COG2723	6-phospho-beta-galactosidase activity
APQ97_RS02220	COG2723	6-phospho-beta-galactosidase activity
APQ97_RS02225	COG0095	Lipoate-protein ligase
APQ97_RS02235	COG0629	single-stranded DNA binding
APQ97_RS02240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APQ97_RS02255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
APQ97_RS02260	COG0006	proline dipeptidase activity
APQ97_RS02275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APQ97_RS02280	COG1609	Transcriptional regulator
APQ97_RS02285	COG1621	beta-fructofuranosidase activity
APQ97_RS02290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APQ97_RS02290	COG1263	PTS System
APQ97_RS02290	COG2190	(PTS) system
APQ97_RS02295	COG1940	carbohydrate kinase activity
APQ97_RS02305	COG0653	protein targeting
APQ97_RS02310	COG0736	holo-[acyl-carrier-protein] synthase activity
APQ97_RS02315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APQ97_RS02330	COG0527	aspartate kinase activity
APQ97_RS02335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APQ97_RS02340	COG1024	Enoyl-CoA hydratase
APQ97_RS02350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APQ97_RS02360	COG2070	2-Nitropropane dioxygenase
APQ97_RS02365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
APQ97_RS02370	COG1028	Short-chain dehydrogenase reductase Sdr
APQ97_RS02390	COG0439	Biotin carboxylase
APQ97_RS02445	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
APQ97_RS02455	COG3177	Filamentation induced by cAMP protein fic
APQ97_RS02480	COG3716	PTS system mannose fructose sorbose family IID component
APQ97_RS02485	COG3715	PTS system
APQ97_RS02495	COG0561	phosphatase activity
APQ97_RS02500	COG2252	PERMEase
APQ97_RS02505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
APQ97_RS02510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APQ97_RS02520	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
APQ97_RS02525	COG1464	Belongs to the NlpA lipoprotein family
APQ97_RS02530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
APQ97_RS02535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APQ97_RS02560	COG0751	glycine-tRNA ligase activity
APQ97_RS02565	COG4224	UPF0291 protein
APQ97_RS02575	COG0534	Mate efflux family protein
APQ97_RS02580	COG0569	domain protein
APQ97_RS02585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
APQ97_RS02595	COG1252	NADH dehydrogenase
APQ97_RS02600	COG0142	geranyltranstransferase activity
APQ97_RS02605	COG4939	FMN-binding domain protein
APQ97_RS02650	COG0275	rRNA processing
APQ97_RS02660	COG0768	penicillin binding
APQ97_RS02665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APQ97_RS02675	COG1132	(ABC) transporter
APQ97_RS02680	COG1132	(ABC) transporter
APQ97_RS02685	COG1011	Hydrolase
APQ97_RS02705	COG1737	Transcriptional regulator
APQ97_RS02715	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
APQ97_RS02720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APQ97_RS02725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
APQ97_RS02730	COG0237	dephospho-CoA kinase activity
APQ97_RS02735	COG2814	Major facilitator Superfamily
APQ97_RS02740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
APQ97_RS02750	COG0557	exoribonuclease II activity
APQ97_RS02755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
APQ97_RS02760	COG1063	alcohol dehydrogenase
APQ97_RS02775	COG2217	Heavy metal translocating P-type atpase
APQ97_RS02780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APQ97_RS02790	COG1136	(ABC) transporter
APQ97_RS02800	COG3547	Transposase (IS116 IS110 IS902 family)
APQ97_RS02810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APQ97_RS02810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APQ97_RS02820	COG1832	CoA-binding protein
APQ97_RS02830	COG0343	queuine tRNA-ribosyltransferase activity
APQ97_RS02840	COG1609	Transcriptional regulator
APQ97_RS02855	COG0438	transferase activity, transferring glycosyl groups
APQ97_RS02870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APQ97_RS02875	COG0765	amino acid transport
APQ97_RS02880	COG0765	amino acid transport
APQ97_RS02885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APQ97_RS02895	COG0745	RESPONSE REGULATOR receiver
APQ97_RS02905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
APQ97_RS02920	COG0488	(ABC) transporter
APQ97_RS02925	COG0768	penicillin binding
APQ97_RS02930	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APQ97_RS02935	COG1181	Belongs to the D-alanine--D-alanine ligase family
APQ97_RS02955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
APQ97_RS02965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
APQ97_RS02980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APQ97_RS03000	COG1609	Transcriptional regulator
APQ97_RS03005	COG4209	transmembrane transport
APQ97_RS03010	COG0395	ABC-type sugar transport system, permease component
APQ97_RS03015	COG1653	transport
APQ97_RS03025	COG0697	spore germination
APQ97_RS03025	COG1674	ftsk spoiiie
APQ97_RS03030	COG0346	lactoylglutathione lyase activity
APQ97_RS03055	COG0625	glutathione transferase activity
APQ97_RS03060	COG2244	polysaccharide biosynthetic process
APQ97_RS03065	COG0528	UMP kinase activity
APQ97_RS03070	COG0233	cytoplasmic translational termination
APQ97_RS03075	COG2996	Protein conserved in bacteria
APQ97_RS03090	COG4479	Belongs to the UPF0346 family
APQ97_RS03095	COG1702	phosphate starvation-inducible protein PhoH
APQ97_RS03105	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APQ97_RS03110	COG2807	transmembrane transport
APQ97_RS03120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APQ97_RS03125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APQ97_RS03135	COG1234	tRNA 3'-trailer cleavage
APQ97_RS03140	COG0300	oxidoreductase activity
APQ97_RS03150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APQ97_RS03155	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
APQ97_RS03155	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
APQ97_RS03165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APQ97_RS03180	COG2384	SAM-dependent methyltransferase
APQ97_RS03185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APQ97_RS03195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APQ97_RS03210	COG1088	dTDP-glucose 4,6-dehydratase activity
APQ97_RS03215	COG1091	dTDP-4-dehydrorhamnose reductase activity
APQ97_RS03245	COG1216	Glycosyl transferase, family 2
APQ97_RS03245	COG1442	glycosyl transferase family 8
APQ97_RS03275	COG1442	glycosyl transferase family 8
APQ97_RS03280	COG1442	glycosyl transferase family 8
APQ97_RS03280	COG1216	Glycosyl transferase, family 2
APQ97_RS03325	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
APQ97_RS03335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
APQ97_RS03350	COG1368	sulfuric ester hydrolase activity
APQ97_RS03355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
APQ97_RS03360	COG0710	3-dehydroquinate dehydratase activity
APQ97_RS03365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
APQ97_RS03370	COG0287	Prephenate dehydrogenase
APQ97_RS03375	COG3679	Belongs to the UPF0342 family
APQ97_RS03385	COG3142	Participates in the control of copper homeostasis
APQ97_RS03400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APQ97_RS03405	COG1534	Rna-binding protein
APQ97_RS03410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APQ97_RS03415	COG1713	HD superfamily hydrolase involved in NAD metabolism
APQ97_RS03430	COG0799	negative regulation of ribosome biogenesis
APQ97_RS03435	COG2226	methyltransferase
APQ97_RS03450	COG0789	Transcriptional regulator
APQ97_RS03470	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
APQ97_RS03475	COG0077	Prephenate dehydratase
APQ97_RS03485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APQ97_RS03490	COG0562	UDP-galactopyranose mutase
APQ97_RS03500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APQ97_RS03515	COG0436	Aminotransferase
APQ97_RS03535	COG0534	Mate efflux family protein
APQ97_RS03540	COG0251	oxidation-reduction process
APQ97_RS03545	COG1660	Displays ATPase and GTPase activities
APQ97_RS03550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
APQ97_RS03555	COG1481	regulation of sporulation
APQ97_RS03580	COG0454	-acetyltransferase
APQ97_RS03585	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APQ97_RS03590	COG0549	Belongs to the carbamate kinase family
APQ97_RS03595	COG1288	antiporter activity
APQ97_RS03600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
APQ97_RS03605	COG3583	domain protein
APQ97_RS03605	COG3525	Glycosyl hydrolase, family 20, catalytic domain
APQ97_RS03605	COG3064	Membrane
APQ97_RS03610	COG1438	arginine binding
APQ97_RS03615	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APQ97_RS03620	COG0363	glucosamine-6-phosphate deaminase activity
APQ97_RS03640	COG0463	Glycosyl transferase, family 2
APQ97_RS03680	COG1696	Membrane protein involved in D-alanine export
APQ97_RS03685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APQ97_RS03690	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APQ97_RS03700	COG0435	Glutathione S-transferase
APQ97_RS03705	COG1187	pseudouridine synthase activity
APQ97_RS03710	COG0386	Belongs to the glutathione peroxidase family
APQ97_RS03715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APQ97_RS03720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APQ97_RS03725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
APQ97_RS03730	COG1120	ATPase activity
APQ97_RS03735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APQ97_RS03740	COG0204	Acyl-transferase
APQ97_RS03745	COG1555	photosystem II stabilization
APQ97_RS03745	COG1596	polysaccharide export
APQ97_RS03750	COG2333	competence protein COMEC
APQ97_RS03750	COG0658	competence protein
APQ97_RS03760	COG0517	IMP dehydrogenase activity
APQ97_RS03775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APQ97_RS03780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APQ97_RS03785	COG0470	DNA polymerase III
APQ97_RS03790	COG4467	Involved in initiation control of chromosome replication
APQ97_RS03800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
APQ97_RS03810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
APQ97_RS03815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APQ97_RS03820	COG1393	Belongs to the ArsC family
APQ97_RS03830	COG0708	Exodeoxyribonuclease III
APQ97_RS03840	COG0531	amino acid
APQ97_RS03870	COG1061	Type III restriction enzyme res subunit
APQ97_RS03875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
APQ97_RS03895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APQ97_RS03900	COG4684	Psort location CytoplasmicMembrane, score
APQ97_RS03905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APQ97_RS03915	COG2759	Belongs to the formate--tetrahydrofolate ligase family
APQ97_RS03955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APQ97_RS03960	COG1349	DNA-binding transcription factor activity
APQ97_RS03970	COG1447	Phosphotransferase system cellobiose-specific component IIA
APQ97_RS03975	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APQ97_RS03980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APQ97_RS03985	COG1882	Formate acetyltransferase
APQ97_RS04005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APQ97_RS04010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APQ97_RS04015	COG2801	Transposase and inactivated derivatives
APQ97_RS04025	COG1164	Oligoendopeptidase f
APQ97_RS04040	COG0210	DNA helicase
APQ97_RS04085	COG1131	(ABC) transporter
APQ97_RS04115	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
APQ97_RS04120	COG1074	ATP-dependent DNA helicase activity
APQ97_RS04130	COG0187	DNA topoisomerase II activity
APQ97_RS04135	COG2184	nucleotidyltransferase activity
APQ97_RS04150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APQ97_RS04160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
APQ97_RS04180	COG0539	negative regulation of cytoplasmic translation
APQ97_RS04205	COG1104	cysteine desulfurase activity
APQ97_RS04210	COG0301	tRNA thio-modification
APQ97_RS04215	COG1114	Component of the transport system for branched-chain amino acids
APQ97_RS04220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
APQ97_RS04225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
APQ97_RS04250	COG0564	pseudouridine synthase activity
APQ97_RS04255	COG2824	Alkylphosphonate utilization operon protein PhnA
APQ97_RS04265	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APQ97_RS04270	COG0540	Belongs to the ATCase OTCase family
APQ97_RS04275	COG0505	Belongs to the CarA family
APQ97_RS04285	COG2521	methyltransferase
APQ97_RS04285	COG2136	Putative SAM-dependent methyltransferase
APQ97_RS04290	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
APQ97_RS04300	COG0228	four-way junction DNA binding
APQ97_RS04315	COG1132	(ABC) transporter
APQ97_RS04320	COG0726	polysaccharide deacetylase
APQ97_RS04330	COG0083	homoserine kinase activity
APQ97_RS04340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
APQ97_RS04345	COG3842	ATPase activity
APQ97_RS04350	COG1176	ABC-type spermidine putrescine transport system, permease component I
APQ97_RS04355	COG1177	transmembrane transport
APQ97_RS04365	COG0038	chloride channel
APQ97_RS04380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
APQ97_RS04385	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APQ97_RS04395	COG0534	Mate efflux family protein
APQ97_RS04400	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APQ97_RS04405	COG0336	Belongs to the RNA methyltransferase TrmD family
APQ97_RS04410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APQ97_RS04415	COG1349	DNA-binding transcription factor activity
APQ97_RS04420	COG1105	Belongs to the carbohydrate kinase PfkB family
APQ97_RS04425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APQ97_RS04425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APQ97_RS04425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APQ97_RS04435	COG1307	EDD domain protein, DegV family
APQ97_RS04440	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
APQ97_RS04445	COG0617	tRNA 3'-terminal CCA addition
APQ97_RS04450	COG0488	(ABC) transporter
APQ97_RS04460	COG1940	carbohydrate kinase activity
APQ97_RS04475	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APQ97_RS04480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APQ97_RS04490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APQ97_RS04505	COG0481	GTPase activity
APQ97_RS04535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APQ97_RS04540	COG2890	protein-(glutamine-N5) methyltransferase activity
APQ97_RS04545	COG0009	L-threonylcarbamoyladenylate synthase
APQ97_RS04555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APQ97_RS04565	COG0741	lytic transglycosylase activity
APQ97_RS04570	COG4221	oxidoreductase activity
APQ97_RS04595	COG1401	restriction endodeoxyribonuclease activity
APQ97_RS04600	COG4268	DNA restriction-modification system
APQ97_RS04610	COG2188	Transcriptional regulator
APQ97_RS04615	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APQ97_RS04620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APQ97_RS04635	COG1660	Displays ATPase and GTPase activities
APQ97_RS04640	COG4974	Belongs to the 'phage' integrase family
APQ97_RS04655	COG0745	RESPONSE REGULATOR receiver
APQ97_RS04675	COG1136	(ABC) transporter
APQ97_RS04705	COG2382	esterase
APQ97_RS04715	COG3708	Transcriptional regulator
APQ97_RS04715	COG2207	Transcriptional regulator
APQ97_RS04720	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
APQ97_RS04725	COG0647	UMP catabolic process
APQ97_RS04730	COG4974	Belongs to the 'phage' integrase family
APQ97_RS04740	COG1396	sequence-specific DNA binding
APQ97_RS04775	COG0745	RESPONSE REGULATOR receiver
APQ97_RS04780	COG2205	protein histidine kinase activity
APQ97_RS04785	COG3843	relaxase mobilization nuclease domain protein
APQ97_RS04800	COG0613	PHP domain protein
APQ97_RS04805	COG0542	response to heat
APQ97_RS04810	COG1396	sequence-specific DNA binding
APQ97_RS04845	COG4443	Transcriptional Coactivator p15 (PC4)
APQ97_RS04850	COG1475	DNA binding
APQ97_RS05015	COG0222	ribosome binding
APQ97_RS05020	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APQ97_RS05025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APQ97_RS05030	COG0758	DNA mediated transformation
APQ97_RS05035	COG0110	maltose O-acetyltransferase activity
APQ97_RS05040	COG1937	Protein conserved in bacteria
APQ97_RS05050	COG0446	pyridine nucleotide-disulphide oxidoreductase
APQ97_RS05060	COG1272	protein, Hemolysin III
APQ97_RS05070	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APQ97_RS05075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APQ97_RS05085	COG0424	maF-like protein
APQ97_RS05090	COG0737	Belongs to the 5'-nucleotidase family
APQ97_RS05100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APQ97_RS05105	COG0463	Glycosyl transferase, family 2
APQ97_RS05115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
APQ97_RS05120	COG0284	orotidine-5'-phosphate decarboxylase activity
APQ97_RS05125	COG0167	dihydroorotate dehydrogenase activity
APQ97_RS05140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
APQ97_RS05150	COG0297	glycogen (starch) synthase activity
APQ97_RS05160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APQ97_RS05200	COG1126	abc transporter atp-binding protein
APQ97_RS05210	COG0488	(ABC) transporter
APQ97_RS05270	COG4372	Transposase
APQ97_RS05275	COG1454	alcohol dehydrogenase
APQ97_RS05290	COG1454	alcohol dehydrogenase
APQ97_RS05315	COG3716	PTS system mannose fructose sorbose family IID component
APQ97_RS05325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APQ97_RS05345	COG1070	Carbohydrate kinase
APQ97_RS05400	COG3711	transcriptional antiterminator
APQ97_RS05405	COG3684	Belongs to the aldolase LacD family
APQ97_RS05410	COG1105	Belongs to the carbohydrate kinase PfkB family
APQ97_RS05415	COG0698	ribose 5-phosphate isomerase
APQ97_RS05420	COG0698	ribose 5-phosphate isomerase
APQ97_RS05425	COG1349	DNA-binding transcription factor activity
APQ97_RS05455	COG1396	sequence-specific DNA binding
APQ97_RS05460	COG1194	a g-specific adenine glycosylase
APQ97_RS05470	COG1132	(ABC) transporter
APQ97_RS05475	COG1132	(ABC) transporter
APQ97_RS05480	COG0280	phosphate acetyltransferase
APQ97_RS05485	COG0564	pseudouridine synthase activity
APQ97_RS05490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APQ97_RS05495	COG2357	RelA SpoT domain protein
APQ97_RS05500	COG4116	CYTH
APQ97_RS05510	COG1104	cysteine desulfurase activity
APQ97_RS05525	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APQ97_RS05530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
APQ97_RS05540	COG3764	Sortase (surface protein transpeptidase)
APQ97_RS05545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APQ97_RS05550	COG0039	L-malate dehydrogenase activity
APQ97_RS05555	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APQ97_RS05565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APQ97_RS05570	COG1079	Belongs to the binding-protein-dependent transport system permease family
APQ97_RS05575	COG4603	Belongs to the binding-protein-dependent transport system permease family
APQ97_RS05580	COG3845	ABC transporter
APQ97_RS05585	COG1744	ABC transporter substrate-binding protein PnrA-like
APQ97_RS05600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
APQ97_RS05605	COG2813	Specifically methylates the guanine in position
APQ97_RS05610	COG1072	(Pantothenic acid kinase))
APQ97_RS05615	COG0268	Binds directly to 16S ribosomal RNA
APQ97_RS05625	COG5002	protein histidine kinase activity
APQ97_RS05630	COG0745	RESPONSE REGULATOR receiver
APQ97_RS05645	COG0704	Plays a role in the regulation of phosphate uptake
APQ97_RS05650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
APQ97_RS05655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
APQ97_RS05660	COG0581	inorganic phosphate transmembrane transporter activity
APQ97_RS05665	COG0573	inorganic phosphate transmembrane transporter activity
APQ97_RS05675	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
APQ97_RS05675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APQ97_RS05680	COG0483	inositol monophosphate 1-phosphatase activity
APQ97_RS05685	COG4476	Belongs to the UPF0223 family
APQ97_RS05690	COG1393	Belongs to the ArsC family
APQ97_RS05695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
APQ97_RS05700	COG0196	riboflavin kinase activity
APQ97_RS05705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APQ97_RS05745	COG0561	phosphatase activity
APQ97_RS05750	COG2195	Cleaves the N-terminal amino acid of tripeptides
APQ97_RS05770	COG1695	Transcriptional regulator
APQ97_RS05790	COG3759	membrane
APQ97_RS05795	COG1846	Transcriptional regulator
APQ97_RS05810	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APQ97_RS05815	COG2610	gluconate transmembrane transporter activity
APQ97_RS05835	COG0302	gtp cyclohydrolase
APQ97_RS05840	COG1051	belongs to the nudix hydrolase family
APQ97_RS05865	COG0072	phenylalanine-tRNA ligase activity
APQ97_RS05865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APQ97_RS05895	COG1028	Short-chain dehydrogenase reductase Sdr
APQ97_RS05900	COG1312	Catalyzes the dehydration of D-mannonate
APQ97_RS05910	COG0800	Aldolase
APQ97_RS05920	COG3250	beta-galactosidase activity
APQ97_RS05945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APQ97_RS05955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
APQ97_RS05960	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APQ97_RS05965	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APQ97_RS05970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APQ97_RS05975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APQ97_RS05980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APQ97_RS05985	COG0356	it plays a direct role in the translocation of protons across the membrane
APQ97_RS05995	COG1597	lipid kinase activity
APQ97_RS06005	COG0701	Predicted permease
APQ97_RS06010	COG3689	TIGRFAM TIGR03943 family protein
APQ97_RS06015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APQ97_RS06030	COG0552	protein localization to endoplasmic reticulum
APQ97_RS06035	COG0561	phosphatase activity
APQ97_RS06040	COG0561	phosphatase activity
APQ97_RS06045	COG1196	nuclear chromosome segregation
APQ97_RS06080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
APQ97_RS06085	COG0538	isocitrate dehydrogenase activity
APQ97_RS06090	COG0372	Belongs to the citrate synthase family
APQ97_RS06095	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
APQ97_RS06100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
APQ97_RS06105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APQ97_RS06110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APQ97_RS06115	COG1609	Transcriptional regulator
APQ97_RS06135	COG5492	domain, Protein
APQ97_RS06150	COG3716	PTS system mannose fructose sorbose family IID component
APQ97_RS06160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APQ97_RS06165	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
APQ97_RS06190	COG1028	Short-chain dehydrogenase reductase Sdr
APQ97_RS06225	COG1476	TRANSCRIPTIONal
APQ97_RS06245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APQ97_RS06255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
APQ97_RS06260	COG4122	O-methyltransferase activity
APQ97_RS06285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APQ97_RS06285	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APQ97_RS06295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
APQ97_RS06300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
APQ97_RS06305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APQ97_RS06310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
APQ97_RS06315	COG1116	anion transmembrane transporter activity
APQ97_RS06315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
APQ97_RS06320	COG4120	Belongs to the binding-protein-dependent transport system permease family
APQ97_RS06340	COG3684	Belongs to the aldolase LacD family
APQ97_RS06350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APQ97_RS06355	COG1126	abc transporter atp-binding protein
APQ97_RS06360	COG0765	amino acid transport
APQ97_RS06365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
APQ97_RS06400	COG1192	Involved in chromosome partitioning
APQ97_RS06415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
APQ97_RS06435	COG3843	relaxase mobilization nuclease domain protein
APQ97_RS06495	COG1705	Flagellar rod assembly protein muramidase FlgJ
APQ97_RS06495	COG3942	CHAP domain
APQ97_RS06565	COG0657	acetylesterase activity
APQ97_RS06565	COG2755	lipolytic protein G-D-S-L family
APQ97_RS06570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
APQ97_RS06585	COG0469	pyruvate kinase activity
APQ97_RS06590	COG0205	6-phosphofructokinase activity
APQ97_RS06600	COG2188	Transcriptional regulator
APQ97_RS06605	COG1131	(ABC) transporter
APQ97_RS06615	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
APQ97_RS06645	COG2151	metal-sulfur cluster biosynthetic enzyme
APQ97_RS06650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APQ97_RS06655	COG0358	DNA primase activity
APQ97_RS06660	COG1970	mechanosensitive ion channel activity
APQ97_RS06665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
APQ97_RS06670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
APQ97_RS06680	COG0647	UMP catabolic process
APQ97_RS06685	COG1051	belongs to the nudix hydrolase family
APQ97_RS06695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
APQ97_RS06705	COG0058	SHG alpha-glucan phosphorylase activity
APQ97_RS06710	COG0813	purine-nucleoside phosphorylase activity
APQ97_RS06715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
APQ97_RS06725	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
APQ97_RS06730	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
APQ97_RS06750	COG1518	maintenance of DNA repeat elements
APQ97_RS06765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APQ97_RS06780	COG2268	Band 7 protein
APQ97_RS06785	COG1704	LemA family
APQ97_RS06795	COG1573	uracil-dna glycosylase
APQ97_RS06815	COG2226	methyltransferase
APQ97_RS06820	COG0488	(ABC) transporter
APQ97_RS06825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APQ97_RS06840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
APQ97_RS06845	COG3442	glutamine amidotransferase
APQ97_RS06850	COG2226	methyltransferase
APQ97_RS06860	COG0488	(ABC) transporter
APQ97_RS06895	COG2801	Transposase and inactivated derivatives
APQ97_RS06910	COG3842	ATPase activity
APQ97_RS06930	COG1263	PTS System
APQ97_RS06930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APQ97_RS06930	COG2190	(PTS) system
APQ97_RS06935	COG3711	transcriptional antiterminator
APQ97_RS06940	COG1293	RNA-binding protein homologous to eukaryotic snRNP
APQ97_RS06945	COG3527	Alpha-acetolactate decarboxylase
APQ97_RS06955	COG0628	permease
APQ97_RS06960	COG2706	6-phosphogluconolactonase activity
APQ97_RS06970	COG1011	Hydrolase
APQ97_RS07000	COG0560	Phosphoserine phosphatase
APQ97_RS07005	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APQ97_RS07010	COG0187	DNA topoisomerase II activity
APQ97_RS07015	COG0693	protein deglycase activity
APQ97_RS07020	COG0772	Belongs to the SEDS family
APQ97_RS07040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
APQ97_RS07045	COG0716	FMN binding
APQ97_RS07055	COG0287	Prephenate dehydrogenase
APQ97_RS07055	COG1605	Chorismate mutase
APQ97_RS07060	COG0038	chloride channel
APQ97_RS07305	COG3561	AntA/AntB antirepressor
APQ97_RS07590	COG3561	AntA/AntB antirepressor
APQ97_RS07640	COG0737	Belongs to the 5'-nucleotidase family
APQ97_RS07645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
APQ97_RS07650	COG1466	dna polymerase III delta subunit
APQ97_RS07685	COG0683	leucine binding
APQ97_RS07700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APQ97_RS07705	COG0366	Alpha amylase catalytic
APQ97_RS07715	COG0395	ABC-type sugar transport system, permease component
APQ97_RS07720	COG1175	transmembrane transport
APQ97_RS07725	COG1653	transport
APQ97_RS07735	COG2207	Transcriptional regulator
APQ97_RS07740	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
APQ97_RS07745	COG0626	cystathionine gamma-synthase activity
APQ97_RS07765	COG3547	Transposase (IS116 IS110 IS902 family)
APQ97_RS07770	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
APQ97_RS07775	COG2827	Endonuclease containing a URI domain
APQ97_RS07800	COG0640	Transcriptional regulator
APQ97_RS07805	COG0513	Belongs to the DEAD box helicase family
APQ97_RS07810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APQ97_RS07860	COG2177	Part of the ABC transporter FtsEX involved in
APQ97_RS07865	COG2884	Cell division ATP-binding protein ftsE
APQ97_RS07870	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APQ97_RS07875	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APQ97_RS07910	COG1078	dGTPase activity
APQ97_RS07925	COG0149	triose-phosphate isomerase activity
APQ97_RS07930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APQ97_RS07945	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
APQ97_RS07950	COG0772	Belongs to the SEDS family
APQ97_RS07970	COG3859	Proton-coupled thiamine transporter YuaJ
APQ97_RS07980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APQ97_RS07990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
APQ97_RS08025	COG0577	efflux transmembrane transporter activity
APQ97_RS08030	COG1136	(ABC) transporter
APQ97_RS08035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APQ97_RS08050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
APQ97_RS08060	COG1268	BioY protein
APQ97_RS08065	COG4443	Transcriptional Coactivator p15 (PC4)
APQ97_RS08075	COG0826	peptidase U32
APQ97_RS08090	COG0789	Transcriptional regulator
APQ97_RS08125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APQ97_RS08135	COG0765	amino acid transport
APQ97_RS08140	COG4703	Protein of unknown function (DUF1797)
APQ97_RS08145	COG0542	response to heat
APQ97_RS08150	COG0494	nUDIX hydrolase
APQ97_RS08150	COG0406	alpha-ribazole phosphatase activity
APQ97_RS08175	COG3599	regulation of cell shape
APQ97_RS08190	COG1799	cell septum assembly
APQ97_RS08195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APQ97_RS08200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APQ97_RS08215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APQ97_RS08245	COG1227	inorganic diphosphatase activity
APQ97_RS08255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APQ97_RS08260	COG1253	flavin adenine dinucleotide binding
APQ97_RS08265	COG1119	ATPase activity
APQ97_RS08270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
APQ97_RS08280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APQ97_RS08285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
APQ97_RS08300	COG4470	Protein conserved in bacteria
APQ97_RS08305	COG3480	Lon protease (S16) C-terminal proteolytic domain
APQ97_RS08310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APQ97_RS08315	COG0742	ribosomal rna small subunit methyltransferase
APQ97_RS08325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APQ97_RS08330	COG4483	Protein conserved in bacteria
APQ97_RS08335	COG2197	response regulator
APQ97_RS08340	COG4585	Histidine kinase
APQ97_RS08340	COG2203	Gaf domain
APQ97_RS08345	COG0842	Transport permease protein
APQ97_RS08350	COG1131	(ABC) transporter
APQ97_RS08370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APQ97_RS08380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
APQ97_RS08380	COG2755	lipolytic protein G-D-S-L family
APQ97_RS08385	COG0671	phosphoesterase, PA-phosphatase related
APQ97_RS08390	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APQ97_RS08405	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
APQ97_RS08410	COG1187	pseudouridine synthase activity
APQ97_RS08415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APQ97_RS08420	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APQ97_RS08425	COG0582	viral genome integration into host DNA
APQ97_RS08445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
APQ97_RS08450	COG3763	UPF0154 protein
APQ97_RS08460	COG3579	cysteine-type endopeptidase activity
APQ97_RS08475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APQ97_RS08480	COG1254	Belongs to the acylphosphatase family
APQ97_RS08490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
APQ97_RS08495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APQ97_RS08510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
APQ97_RS08520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
APQ97_RS08535	COG1160	GTP binding
APQ97_RS08545	COG1484	DNA-dependent DNA replication
APQ97_RS08555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APQ97_RS08560	COG0628	permease
APQ97_RS08565	COG0745	RESPONSE REGULATOR receiver
APQ97_RS08570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APQ97_RS08580	COG0492	ferredoxin-NADP+ reductase activity
APQ97_RS08590	COG0513	Belongs to the DEAD box helicase family
APQ97_RS08625	COG0494	nUDIX hydrolase
APQ97_RS08630	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APQ97_RS08640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APQ97_RS08645	COG1028	Short-chain dehydrogenase reductase Sdr
APQ97_RS08670	COG0577	efflux transmembrane transporter activity
APQ97_RS08675	COG1136	(ABC) transporter
APQ97_RS08680	COG2205	protein histidine kinase activity
APQ97_RS08695	COG0436	Aminotransferase
APQ97_RS08705	COG1174	glycine betaine transport
APQ97_RS08710	COG1125	glycine betaine transport
APQ97_RS08710	COG0517	IMP dehydrogenase activity
APQ97_RS08730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APQ97_RS08735	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APQ97_RS08740	COG1482	cell wall glycoprotein biosynthetic process
APQ97_RS08755	COG3091	SprT-like family
APQ97_RS08760	COG2183	response to ionizing radiation
APQ97_RS08780	COG0656	L-ascorbic acid biosynthetic process
APQ97_RS08785	COG4708	membrane
APQ97_RS08790	COG2246	polysaccharide biosynthetic process
APQ97_RS08800	COG0024	Methionine aminopeptidase
APQ97_RS08810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APQ97_RS08820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APQ97_RS08825	COG2131	deaminase
APQ97_RS08835	COG1363	Peptidase, m42
APQ97_RS08855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APQ97_RS08860	COG1956	GAF domain-containing protein
APQ97_RS08880	COG0673	inositol 2-dehydrogenase activity
APQ97_RS08885	COG0513	Belongs to the DEAD box helicase family
APQ97_RS08890	COG0726	polysaccharide deacetylase
APQ97_RS08905	COG0183	Belongs to the thiolase family
APQ97_RS08910	COG3425	synthase
APQ97_RS08945	COG0776	regulation of translation
APQ97_RS08955	COG2755	lipolytic protein G-D-S-L family
APQ97_RS08960	COG1307	EDD domain protein, DegV family
APQ97_RS08965	COG0497	DNA recombination
APQ97_RS08970	COG1438	arginine binding
APQ97_RS08975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
APQ97_RS08985	COG1722	exodeoxyribonuclease VII activity
APQ97_RS08990	COG1570	exodeoxyribonuclease VII activity
APQ97_RS08995	COG2321	neutral zinc metallopeptidase
APQ97_RS09010	COG1755	Isoprenylcysteine carboxyl methyltransferase
APQ97_RS09015	COG5002	protein histidine kinase activity
APQ97_RS09020	COG0745	RESPONSE REGULATOR receiver
APQ97_RS09100	COG1083	cytidylyl-transferase
APQ97_RS09100	COG2755	lipolytic protein G-D-S-L family
APQ97_RS09115	COG2089	acid synthase
APQ97_RS09145	COG1442	glycosyl transferase family 8
APQ97_RS09145	COG1216	Glycosyl transferase, family 2
APQ97_RS09150	COG1442	glycosyl transferase family 8
APQ97_RS09150	COG1216	Glycosyl transferase, family 2
APQ97_RS09165	COG0438	transferase activity, transferring glycosyl groups
APQ97_RS09180	COG4464	protein tyrosine phosphatase activity
APQ97_RS09190	COG3944	biosynthesis protein
APQ97_RS09195	COG1316	TRANSCRIPTIONal
APQ97_RS09200	COG3022	response to hydroperoxide
APQ97_RS09205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
APQ97_RS09220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APQ97_RS09225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APQ97_RS09230	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APQ97_RS09255	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
APQ97_RS09260	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APQ97_RS09265	COG1609	Transcriptional regulator
APQ97_RS09280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APQ97_RS09285	COG0154	amidase activity
APQ97_RS09290	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APQ97_RS09300	COG0335	large ribosomal subunit rRNA binding
APQ97_RS09310	COG1335	isochorismatase
APQ97_RS09315	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
APQ97_RS09320	COG0436	Aminotransferase
APQ97_RS09350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APQ97_RS09385	COG0227	Belongs to the bacterial ribosomal protein bL28 family
APQ97_RS09390	COG0191	fructose-bisphosphate aldolase activity
APQ97_RS09400	COG0504	CTP synthase activity
APQ97_RS09405	COG3343	RNA polymerase activity
APQ97_RS09420	COG2801	Transposase and inactivated derivatives
APQ97_RS09450	COG0544	peptidyl-prolyl cis-trans isomerase activity
APQ97_RS09470	COG1902	pentaerythritol trinitrate reductase activity
APQ97_RS09470	COG0446	pyridine nucleotide-disulphide oxidoreductase
APQ97_RS09475	COG4221	oxidoreductase activity
APQ97_RS09500	COG4475	Protein of unknown function (DUF436)
APQ97_RS09525	COG2217	Heavy metal translocating P-type atpase
APQ97_RS09535	COG3655	Transcriptional regulator
APQ97_RS09550	COG0765	amino acid transport
APQ97_RS09555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APQ97_RS09565	COG0095	Lipoate-protein ligase
APQ97_RS09570	COG0484	heat shock protein binding
APQ97_RS09575	COG0443	Heat shock 70 kDa protein
APQ97_RS09580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APQ97_RS09585	COG1420	regulation of RNA biosynthetic process
APQ97_RS09590	COG0588	phosphoglycerate mutase activity
APQ97_RS09595	COG2848	UPF0210 protein
APQ97_RS09600	COG3830	Belongs to the UPF0237 family
APQ97_RS09605	COG1132	(ABC) transporter
APQ97_RS09610	COG1132	(ABC) transporter
APQ97_RS09615	COG1304	FMN binding
APQ97_RS09630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APQ97_RS09635	COG0534	Mate efflux family protein
APQ97_RS09640	COG1129	ABC transporter
APQ97_RS09655	COG1132	(ABC) transporter
APQ97_RS09675	COG1454	alcohol dehydrogenase
APQ97_RS09675	COG1012	belongs to the aldehyde dehydrogenase family
APQ97_RS09680	COG1064	alcohol dehydrogenase
APQ97_RS09685	COG0124	histidyl-tRNA synthetase
APQ97_RS09695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
APQ97_RS09700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
APQ97_RS09715	COG0494	nUDIX hydrolase
APQ97_RS09720	COG0433	COG0433 Predicted ATPase
APQ97_RS09725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
APQ97_RS09735	COG1346	cytolysis
APQ97_RS09740	COG1380	Effector of murein hydrolase LrgA
APQ97_RS09760	COG1511	domain protein
APQ97_RS09765	COG1309	transcriptional regulator
APQ97_RS09770	COG1131	(ABC) transporter
APQ97_RS09785	COG0561	phosphatase activity
APQ97_RS09790	COG2843	Capsule synthesis protein
APQ97_RS09795	COG0167	dihydroorotate dehydrogenase activity
APQ97_RS09800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
APQ97_RS09815	COG0668	transmembrane transport
APQ97_RS09825	COG1115	amino acid carrier protein
APQ97_RS09885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APQ97_RS09885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APQ97_RS09895	COG3118	belongs to the thioredoxin family
APQ97_RS09950	COG1193	negative regulation of DNA recombination
APQ97_RS09965	COG2188	Transcriptional regulator
APQ97_RS09970	COG1263	PTS System
APQ97_RS09970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APQ97_RS09975	COG0366	Alpha amylase catalytic
APQ97_RS09995	COG0681	Belongs to the peptidase S26 family
APQ97_RS10000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
APQ97_RS10005	COG2217	Heavy metal translocating P-type atpase
APQ97_RS10015	COG2217	Heavy metal translocating P-type atpase
APQ97_RS10020	COG0363	glucosamine-6-phosphate deaminase activity
APQ97_RS10055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APQ97_RS10080	COG2910	NAD(P)H-binding
APQ97_RS10095	COG1882	Formate acetyltransferase
APQ97_RS10100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
APQ97_RS10125	COG2222	sugar isomerase
APQ97_RS10130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APQ97_RS10135	COG0584	glycerophosphoryl diester phosphodiesterase
APQ97_RS10140	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APQ97_RS10145	COG3959	Transketolase, thiamine diphosphate binding domain
APQ97_RS10160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APQ97_RS10170	COG2723	6-phospho-beta-galactosidase activity
APQ97_RS10175	COG2081	HI0933 family
APQ97_RS10185	COG1131	(ABC) transporter
APQ97_RS10205	COG2855	membrane
APQ97_RS10225	COG0395	ABC-type sugar transport system, permease component
APQ97_RS10230	COG1175	transmembrane transport
APQ97_RS10240	COG2207	Transcriptional regulator
APQ97_RS10245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APQ97_RS10255	COG1214	PFAM Peptidase M22, glycoprotease
APQ97_RS10270	COG0174	glutamine synthetase
APQ97_RS10275	COG0789	Transcriptional regulator
APQ97_RS10285	COG0126	phosphoglycerate kinase activity
APQ97_RS10295	COG3590	peptidase
APQ97_RS10300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APQ97_RS10305	COG0049	tRNA binding
APQ97_RS10315	COG0459	protein refolding
APQ97_RS10340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APQ97_RS10350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
APQ97_RS10360	COG1363	Peptidase, m42
APQ97_RS10365	COG0285	dihydrofolate synthase activity
APQ97_RS10375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APQ97_RS10405	COG4537	Required for transformation and DNA binding
APQ97_RS10410	COG1459	type II secretion system
APQ97_RS10415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APQ97_RS10420	COG1619	proteins homologs of microcin C7 resistance protein MccF
APQ97_RS10430	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APQ97_RS10435	COG0085	RNA polymerase activity
APQ97_RS10440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
APQ97_RS10465	COG3443	Belongs to the bacterial solute-binding protein 9 family
APQ97_RS10465	COG0803	Belongs to the bacterial solute-binding protein 9 family
APQ97_RS10470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
APQ97_RS10475	COG1121	(ABC) transporter
APQ97_RS10580	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
APQ97_RS10585	COG1739	Uncharacterized protein family UPF0029
APQ97_RS10600	COG2815	serine threonine protein kinase
APQ97_RS10600	COG0515	serine threonine protein kinase
APQ97_RS10605	COG0631	protein serine/threonine phosphatase activity
APQ97_RS10610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APQ97_RS10610	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APQ97_RS10615	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APQ97_RS10620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APQ97_RS10625	COG1758	RNA polymerase activity
APQ97_RS10635	COG1418	mRNA catabolic process
APQ97_RS10640	COG1854	S-ribosylhomocysteine lyase activity
APQ97_RS10650	COG0116	Belongs to the methyltransferase superfamily
APQ97_RS10660	COG3599	regulation of cell shape
APQ97_RS10665	COG4474	Belongs to the UPF0398 family
APQ97_RS10670	COG3331	DNA recombination
APQ97_RS10675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
APQ97_RS10680	COG0357	Ribosomal RNA small subunit methyltransferase G
APQ97_RS10695	COG1122	ATPase activity
APQ97_RS10705	COG1054	Belongs to the UPF0176 family
APQ97_RS10715	COG4720	Psort location CytoplasmicMembrane, score
APQ97_RS10725	COG0217	transcriptional regulatory protein
APQ97_RS10740	COG2190	(PTS) system
APQ97_RS10740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APQ97_RS10740	COG1263	PTS System
APQ97_RS10755	COG0058	SHG alpha-glucan phosphorylase activity
APQ97_RS10760	COG1640	4-alpha-glucanotransferase
APQ97_RS10770	COG0242	peptide deformylase activity
APQ97_RS10800	COG0285	dihydrofolate synthase activity
APQ97_RS11005	COG0556	nucleotide-excision repair
APQ97_RS11070	COG4974	Belongs to the 'phage' integrase family
APQ97_RS11085	COG4974	Belongs to the 'phage' integrase family
APQ97_RS11095	COG1098	S1 RNA binding domain
APQ97_RS11135	COG1438	arginine binding
APQ97_RS11140	COG0018	arginyl-trna synthetase
APQ97_RS11160	COG1640	4-alpha-glucanotransferase
APQ97_RS11165	COG2182	Extracellular solute-binding protein
APQ97_RS11170	COG1175	transmembrane transport
APQ97_RS11175	COG3833	ABC-type maltose transport systems, permease component
APQ97_RS11180	COG5521	maltodextrose utilization protein MalA
APQ97_RS11185	COG1609	Transcriptional regulator
APQ97_RS11190	COG1523	belongs to the glycosyl hydrolase 13 family
APQ97_RS11195	COG1780	Probably involved in ribonucleotide reductase function
APQ97_RS11200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APQ97_RS11205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
APQ97_RS11210	COG2153	protein acetylation
APQ97_RS11215	COG4989	oxidoreductase activity
APQ97_RS11220	COG1216	Glycosyl transferase, family 2
APQ97_RS11240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APQ97_RS11250	COG0305	Participates in initiation and elongation during chromosome replication
APQ97_RS11255	COG0359	binds to the 23S rRNA
APQ97_RS11265	COG0445	tRNA wobble uridine modification
APQ97_RS11270	COG0494	nUDIX hydrolase
APQ97_RS11275	COG1733	regulation of RNA biosynthetic process
APQ97_RS11285	COG0482	sulfurtransferase activity
APQ97_RS11290	COG1760	l-serine dehydratase
APQ97_RS11295	COG1760	l-serine dehydratase
APQ97_RS11305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APQ97_RS11310	COG1122	ATPase activity
APQ97_RS11315	COG1122	ATPase activity
APQ97_RS11320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APQ97_RS11325	COG1426	Protein conserved in bacteria
APQ97_RS11330	COG0612	Peptidase, M16
APQ97_RS11335	COG0612	Peptidase, M16
APQ97_RS11410	COG0582	viral genome integration into host DNA
APQ97_RS11420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APQ97_RS11430	COG0516	GMP reductase activity
APQ97_RS11430	COG0517	IMP dehydrogenase activity
APQ97_RS11440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APQ97_RS11445	COG0488	(ABC) transporter
APQ97_RS11475	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APQ97_RS11480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APQ97_RS11570	COG0592	DNA-directed DNA polymerase activity