locus-tag	class	description
NJAUSS_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NJAUSS_RS00010	COG0592	DNA-directed DNA polymerase activity
NJAUSS_RS00030	COG0012	GTP binding
NJAUSS_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
NJAUSS_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NJAUSS_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NJAUSS_RS00065	COG0037	tRNA processing
NJAUSS_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NJAUSS_RS00185	COG1792	Involved in formation and maintenance of cell shape
NJAUSS_RS00200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NJAUSS_RS00205	COG0436	Aminotransferase
NJAUSS_RS00210	COG1381	Involved in DNA repair and RecF pathway recombination
NJAUSS_RS00215	COG0416	fatty acid biosynthetic process
NJAUSS_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NJAUSS_RS00230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NJAUSS_RS00245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NJAUSS_RS00250	COG0138	bifunctional purine biosynthesis protein purh
NJAUSS_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NJAUSS_RS00280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NJAUSS_RS00300	COG1131	(ABC) transporter
NJAUSS_RS00310	COG1132	(ABC) transporter
NJAUSS_RS00315	COG2255	four-way junction helicase activity
NJAUSS_RS00325	COG0546	phosphoglycolate phosphatase activity
NJAUSS_RS00350	COG0285	dihydrofolate synthase activity
NJAUSS_RS00365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NJAUSS_RS00370	COG0632	four-way junction helicase activity
NJAUSS_RS00380	COG0519	Catalyzes the synthesis of GMP from XMP
NJAUSS_RS00395	COG1393	Belongs to the ArsC family
NJAUSS_RS00400	COG4472	Bacterial protein of unknown function (DUF965)
NJAUSS_RS00405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NJAUSS_RS00410	COG3906	Belongs to the UPF0473 family
NJAUSS_RS00435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NJAUSS_RS00440	COG0088	Forms part of the polypeptide exit tunnel
NJAUSS_RS00445	COG0089	rRNA binding
NJAUSS_RS00450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NJAUSS_RS00455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NJAUSS_RS00460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NJAUSS_RS00465	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NJAUSS_RS00470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NJAUSS_RS00475	COG0255	Belongs to the universal ribosomal protein uL29 family
NJAUSS_RS00480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NJAUSS_RS00485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NJAUSS_RS00490	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NJAUSS_RS00495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NJAUSS_RS00500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NJAUSS_RS00510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NJAUSS_RS00520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NJAUSS_RS00525	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NJAUSS_RS00530	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NJAUSS_RS00535	COG1841	ribosomal large subunit assembly
NJAUSS_RS00545	COG0201	protein transport
NJAUSS_RS00550	COG0563	adenylate kinase activity
NJAUSS_RS00555	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NJAUSS_RS00560	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NJAUSS_RS00565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NJAUSS_RS00575	COG0202	RNA polymerase activity
NJAUSS_RS00665	COG0582	viral genome integration into host DNA
NJAUSS_RS00675	COG2946	Replication initiation factor
NJAUSS_RS00720	COG1121	(ABC) transporter
NJAUSS_RS00725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NJAUSS_RS00730	COG3443	Belongs to the bacterial solute-binding protein 9 family
NJAUSS_RS00730	COG0803	Belongs to the bacterial solute-binding protein 9 family
NJAUSS_RS00760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NJAUSS_RS00765	COG0085	RNA polymerase activity
NJAUSS_RS00770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NJAUSS_RS00785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NJAUSS_RS00790	COG1459	type II secretion system
NJAUSS_RS00795	COG4537	Required for transformation and DNA binding
NJAUSS_RS00825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NJAUSS_RS00835	COG0285	dihydrofolate synthase activity
NJAUSS_RS00840	COG1363	Peptidase, m42
NJAUSS_RS00850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NJAUSS_RS00860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NJAUSS_RS00885	COG0459	protein refolding
NJAUSS_RS00895	COG0049	tRNA binding
NJAUSS_RS00900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NJAUSS_RS00905	COG3590	peptidase
NJAUSS_RS00915	COG0126	phosphoglycerate kinase activity
NJAUSS_RS00925	COG0789	Transcriptional regulator
NJAUSS_RS00930	COG0174	glutamine synthetase
NJAUSS_RS00945	COG1214	PFAM Peptidase M22, glycoprotease
NJAUSS_RS00955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NJAUSS_RS00960	COG2207	Transcriptional regulator
NJAUSS_RS00970	COG1175	transmembrane transport
NJAUSS_RS00975	COG0395	ABC-type sugar transport system, permease component
NJAUSS_RS00995	COG2855	membrane
NJAUSS_RS01020	COG1131	(ABC) transporter
NJAUSS_RS01025	COG2081	HI0933 family
NJAUSS_RS01030	COG2723	6-phospho-beta-galactosidase activity
NJAUSS_RS01040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJAUSS_RS01055	COG3959	Transketolase, thiamine diphosphate binding domain
NJAUSS_RS01060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NJAUSS_RS01065	COG0584	glycerophosphoryl diester phosphodiesterase
NJAUSS_RS01070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NJAUSS_RS01075	COG2222	sugar isomerase
NJAUSS_RS01095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NJAUSS_RS01100	COG1882	Formate acetyltransferase
NJAUSS_RS01115	COG2910	NAD(P)H-binding
NJAUSS_RS01145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NJAUSS_RS01180	COG0363	glucosamine-6-phosphate deaminase activity
NJAUSS_RS01190	COG2217	Heavy metal translocating P-type atpase
NJAUSS_RS01195	COG2217	Heavy metal translocating P-type atpase
NJAUSS_RS01200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NJAUSS_RS01205	COG0681	Belongs to the peptidase S26 family
NJAUSS_RS01230	COG0366	Alpha amylase catalytic
NJAUSS_RS01235	COG1263	PTS System
NJAUSS_RS01235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJAUSS_RS01240	COG2188	Transcriptional regulator
NJAUSS_RS01255	COG1193	negative regulation of DNA recombination
NJAUSS_RS01265	COG3118	belongs to the thioredoxin family
NJAUSS_RS01270	COG0318	PFAM AMP-dependent synthetase and ligase
NJAUSS_RS01275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NJAUSS_RS01275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NJAUSS_RS01295	COG1136	(ABC) transporter
NJAUSS_RS01300	COG1115	amino acid carrier protein
NJAUSS_RS01305	COG0668	transmembrane transport
NJAUSS_RS01320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NJAUSS_RS01325	COG0167	dihydroorotate dehydrogenase activity
NJAUSS_RS01330	COG2843	Capsule synthesis protein
NJAUSS_RS01335	COG0561	phosphatase activity
NJAUSS_RS01350	COG1131	(ABC) transporter
NJAUSS_RS01355	COG1309	transcriptional regulator
NJAUSS_RS01360	COG1511	domain protein
NJAUSS_RS01385	COG1346	cytolysis
NJAUSS_RS01390	COG2116	formate transmembrane transporter activity
NJAUSS_RS01395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NJAUSS_RS01400	COG0433	COG0433 Predicted ATPase
NJAUSS_RS01405	COG0494	nUDIX hydrolase
NJAUSS_RS01430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NJAUSS_RS01435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NJAUSS_RS01440	COG0124	histidyl-tRNA synthetase
NJAUSS_RS01445	COG1064	alcohol dehydrogenase
NJAUSS_RS01450	COG1454	alcohol dehydrogenase
NJAUSS_RS01450	COG1012	belongs to the aldehyde dehydrogenase family
NJAUSS_RS01460	COG4988	ABC transporter
NJAUSS_RS01465	COG1132	(ABC) transporter
NJAUSS_RS01480	COG1129	ABC transporter
NJAUSS_RS01485	COG0534	Mate efflux family protein
NJAUSS_RS01490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NJAUSS_RS01505	COG1304	FMN binding
NJAUSS_RS01510	COG1132	(ABC) transporter
NJAUSS_RS01515	COG1132	(ABC) transporter
NJAUSS_RS01520	COG3830	Belongs to the UPF0237 family
NJAUSS_RS01525	COG2848	UPF0210 protein
NJAUSS_RS01530	COG0588	phosphoglycerate mutase activity
NJAUSS_RS01535	COG1420	regulation of RNA biosynthetic process
NJAUSS_RS01540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NJAUSS_RS01545	COG0443	Heat shock 70 kDa protein
NJAUSS_RS01550	COG0484	heat shock protein binding
NJAUSS_RS01555	COG0095	Lipoate-protein ligase
NJAUSS_RS01565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJAUSS_RS01570	COG0765	amino acid transport
NJAUSS_RS01575	COG3655	Transcriptional regulator
NJAUSS_RS01585	COG2217	Heavy metal translocating P-type atpase
NJAUSS_RS01610	COG4475	Protein of unknown function (DUF436)
NJAUSS_RS01640	COG4221	oxidoreductase activity
NJAUSS_RS01645	COG0446	pyridine nucleotide-disulphide oxidoreductase
NJAUSS_RS01645	COG1902	pentaerythritol trinitrate reductase activity
NJAUSS_RS01650	COG1959	2 iron, 2 sulfur cluster binding
NJAUSS_RS01670	COG0544	peptidyl-prolyl cis-trans isomerase activity
NJAUSS_RS01690	COG3343	RNA polymerase activity
NJAUSS_RS01695	COG0504	CTP synthase activity
NJAUSS_RS01705	COG0191	fructose-bisphosphate aldolase activity
NJAUSS_RS01710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NJAUSS_RS01745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NJAUSS_RS01750	COG0252	asparaginase activity
NJAUSS_RS01765	COG0589	response to stress
NJAUSS_RS01770	COG0436	Aminotransferase
NJAUSS_RS01775	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NJAUSS_RS01780	COG1335	isochorismatase
NJAUSS_RS01785	COG0335	large ribosomal subunit rRNA binding
NJAUSS_RS01795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NJAUSS_RS01800	COG0154	amidase activity
NJAUSS_RS01805	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NJAUSS_RS01810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NJAUSS_RS01815	COG1609	Transcriptional regulator
NJAUSS_RS01820	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NJAUSS_RS01825	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NJAUSS_RS01835	COG3142	Participates in the control of copper homeostasis
NJAUSS_RS01850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NJAUSS_RS01855	COG1534	Rna-binding protein
NJAUSS_RS01860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NJAUSS_RS01865	COG1713	HD superfamily hydrolase involved in NAD metabolism
NJAUSS_RS01875	COG1335	isochorismatase
NJAUSS_RS01880	COG0799	negative regulation of ribosome biogenesis
NJAUSS_RS01885	COG2226	methyltransferase
NJAUSS_RS01890	COG5290	Psort location Cytoplasmic, score
NJAUSS_RS01900	COG0789	Transcriptional regulator
NJAUSS_RS01925	COG0242	peptide deformylase activity
NJAUSS_RS01935	COG1640	4-alpha-glucanotransferase
NJAUSS_RS01940	COG0058	SHG alpha-glucan phosphorylase activity
NJAUSS_RS01955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJAUSS_RS01955	COG1263	PTS System
NJAUSS_RS01955	COG2190	(PTS) system
NJAUSS_RS01970	COG0217	transcriptional regulatory protein
NJAUSS_RS01980	COG4720	Psort location CytoplasmicMembrane, score
NJAUSS_RS01990	COG1054	Belongs to the UPF0176 family
NJAUSS_RS02000	COG1122	ATPase activity
NJAUSS_RS02015	COG0357	Ribosomal RNA small subunit methyltransferase G
NJAUSS_RS02020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NJAUSS_RS02025	COG3331	DNA recombination
NJAUSS_RS02030	COG4474	Belongs to the UPF0398 family
NJAUSS_RS02035	COG3599	regulation of cell shape
NJAUSS_RS02040	COG0116	Belongs to the methyltransferase superfamily
NJAUSS_RS02050	COG1854	S-ribosylhomocysteine lyase activity
NJAUSS_RS02055	COG1418	mRNA catabolic process
NJAUSS_RS02065	COG1758	RNA polymerase activity
NJAUSS_RS02070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NJAUSS_RS02075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NJAUSS_RS02080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NJAUSS_RS02080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NJAUSS_RS02085	COG0631	protein serine/threonine phosphatase activity
NJAUSS_RS02090	COG2815	serine threonine protein kinase
NJAUSS_RS02090	COG0515	serine threonine protein kinase
NJAUSS_RS02115	COG1098	S1 RNA binding domain
NJAUSS_RS02125	COG1739	Uncharacterized protein family UPF0029
NJAUSS_RS02130	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NJAUSS_RS02210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NJAUSS_RS02215	COG2137	regulation of response to DNA damage stimulus
NJAUSS_RS02220	COG3557	Belongs to the UPF0374 family
NJAUSS_RS02230	COG2188	Transcriptional regulator
NJAUSS_RS02235	COG2188	Transcriptional regulator
NJAUSS_RS02245	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJAUSS_RS02255	COG3716	PTS system mannose fructose sorbose family IID component
NJAUSS_RS02265	COG2017	converts alpha-aldose to the beta-anomer
NJAUSS_RS02280	COG0346	lactoylglutathione lyase activity
NJAUSS_RS02330	COG1217	gtp-binding protein TYPA
NJAUSS_RS02345	COG0681	Belongs to the peptidase S26 family
NJAUSS_RS02375	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NJAUSS_RS02390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NJAUSS_RS02395	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NJAUSS_RS02400	COG1799	cell septum assembly
NJAUSS_RS02415	COG3599	regulation of cell shape
NJAUSS_RS02435	COG0406	alpha-ribazole phosphatase activity
NJAUSS_RS02435	COG0494	nUDIX hydrolase
NJAUSS_RS02440	COG0542	response to heat
NJAUSS_RS02445	COG4703	Protein of unknown function (DUF1797)
NJAUSS_RS02450	COG0765	amino acid transport
NJAUSS_RS02460	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NJAUSS_RS02490	COG0789	Transcriptional regulator
NJAUSS_RS02505	COG0826	peptidase U32
NJAUSS_RS02520	COG4443	Transcriptional Coactivator p15 (PC4)
NJAUSS_RS02525	COG1268	BioY protein
NJAUSS_RS02530	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NJAUSS_RS02535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NJAUSS_RS02540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJAUSS_RS02545	COG1136	(ABC) transporter
NJAUSS_RS02550	COG0577	efflux transmembrane transporter activity
NJAUSS_RS02565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NJAUSS_RS02575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NJAUSS_RS02585	COG3859	Proton-coupled thiamine transporter YuaJ
NJAUSS_RS02605	COG0772	Belongs to the SEDS family
NJAUSS_RS02610	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NJAUSS_RS02615	COG1595	DNA-templated transcription, initiation
NJAUSS_RS02625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NJAUSS_RS02630	COG0149	triose-phosphate isomerase activity
NJAUSS_RS02640	COG1078	dGTPase activity
NJAUSS_RS02655	COG2826	transposase and inactivated derivatives, IS30 family
NJAUSS_RS02660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NJAUSS_RS02670	COG1131	(ABC) transporter
NJAUSS_RS02675	COG2188	Transcriptional regulator
NJAUSS_RS02685	COG0205	6-phosphofructokinase activity
NJAUSS_RS02690	COG0469	pyruvate kinase activity
NJAUSS_RS02700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NJAUSS_RS02705	COG2755	lipolytic protein G-D-S-L family
NJAUSS_RS02705	COG0657	acetylesterase activity
NJAUSS_RS02715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NJAUSS_RS02720	COG0765	amino acid transport
NJAUSS_RS02725	COG1126	abc transporter atp-binding protein
NJAUSS_RS02730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJAUSS_RS02745	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NJAUSS_RS02750	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NJAUSS_RS02755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NJAUSS_RS02770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NJAUSS_RS02775	COG3022	response to hydroperoxide
NJAUSS_RS02785	COG3944	biosynthesis protein
NJAUSS_RS02795	COG4464	protein tyrosine phosphatase activity
NJAUSS_RS02810	COG0438	transferase activity, transferring glycosyl groups
NJAUSS_RS02825	COG1216	Glycosyl transferase, family 2
NJAUSS_RS02825	COG1442	glycosyl transferase family 8
NJAUSS_RS02830	COG1442	glycosyl transferase family 8
NJAUSS_RS02830	COG1216	Glycosyl transferase, family 2
NJAUSS_RS02855	COG2089	acid synthase
NJAUSS_RS02870	COG2755	lipolytic protein G-D-S-L family
NJAUSS_RS02870	COG1083	cytidylyl-transferase
NJAUSS_RS02940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NJAUSS_RS02945	COG0077	Prephenate dehydratase
NJAUSS_RS02955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NJAUSS_RS02970	COG0270	DNA (cytosine-5-)-methyltransferase activity
NJAUSS_RS03110	COG1475	DNA binding
NJAUSS_RS03115	COG4443	Transcriptional Coactivator p15 (PC4)
NJAUSS_RS03170	COG1396	sequence-specific DNA binding
NJAUSS_RS03175	COG0542	response to heat
NJAUSS_RS03180	COG0613	PHP domain protein
NJAUSS_RS03195	COG3843	relaxase mobilization nuclease domain protein
NJAUSS_RS03220	COG1131	(ABC) transporter
NJAUSS_RS03275	COG0488	(ABC) transporter
NJAUSS_RS03290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NJAUSS_RS03315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NJAUSS_RS03315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NJAUSS_RS03360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NJAUSS_RS03385	COG0270	DNA (cytosine-5-)-methyltransferase activity
NJAUSS_RS03430	COG4695	Portal protein
NJAUSS_RS03435	COG0740	serine-type endopeptidase activity
NJAUSS_RS03510	COG1388	LysM domain
NJAUSS_RS03510	COG0860	N-Acetylmuramoyl-L-alanine amidase
NJAUSS_RS03540	COG2378	regulation of single-species biofilm formation
NJAUSS_RS03550	COG0456	acetyltransferase
NJAUSS_RS03570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NJAUSS_RS03595	COG0436	Aminotransferase
NJAUSS_RS03615	COG0534	Mate efflux family protein
NJAUSS_RS03620	COG0251	oxidation-reduction process
NJAUSS_RS03625	COG1660	Displays ATPase and GTPase activities
NJAUSS_RS03630	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NJAUSS_RS03635	COG1481	regulation of sporulation
NJAUSS_RS03650	COG0454	-acetyltransferase
NJAUSS_RS03655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NJAUSS_RS03660	COG0549	Belongs to the carbamate kinase family
NJAUSS_RS03665	COG1288	antiporter activity
NJAUSS_RS03670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NJAUSS_RS03675	COG3583	domain protein
NJAUSS_RS03675	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NJAUSS_RS03675	COG3064	Membrane
NJAUSS_RS03680	COG1438	arginine binding
NJAUSS_RS03685	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NJAUSS_RS03690	COG0363	glucosamine-6-phosphate deaminase activity
NJAUSS_RS03715	COG1696	Membrane protein involved in D-alanine export
NJAUSS_RS03720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NJAUSS_RS03725	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NJAUSS_RS03735	COG0435	Glutathione S-transferase
NJAUSS_RS03740	COG1187	pseudouridine synthase activity
NJAUSS_RS03745	COG0386	Belongs to the glutathione peroxidase family
NJAUSS_RS03750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NJAUSS_RS03755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NJAUSS_RS03760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NJAUSS_RS03765	COG1120	ATPase activity
NJAUSS_RS03770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NJAUSS_RS03775	COG0204	Acyl-transferase
NJAUSS_RS03780	COG1596	polysaccharide export
NJAUSS_RS03780	COG1555	photosystem II stabilization
NJAUSS_RS03785	COG0658	competence protein
NJAUSS_RS03785	COG2333	competence protein COMEC
NJAUSS_RS03795	COG0517	IMP dehydrogenase activity
NJAUSS_RS03810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NJAUSS_RS03815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NJAUSS_RS03820	COG0470	DNA polymerase III
NJAUSS_RS03825	COG4467	Involved in initiation control of chromosome replication
NJAUSS_RS03835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NJAUSS_RS03845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NJAUSS_RS03850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NJAUSS_RS03855	COG1393	Belongs to the ArsC family
NJAUSS_RS03865	COG0708	Exodeoxyribonuclease III
NJAUSS_RS03875	COG0531	amino acid
NJAUSS_RS03920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NJAUSS_RS03925	COG4684	Psort location CytoplasmicMembrane, score
NJAUSS_RS03930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NJAUSS_RS03940	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NJAUSS_RS03950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NJAUSS_RS03955	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NJAUSS_RS03970	COG0732	type I restriction modification DNA specificity domain
NJAUSS_RS04005	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NJAUSS_RS04010	COG1349	DNA-binding transcription factor activity
NJAUSS_RS04020	COG1447	Phosphotransferase system cellobiose-specific component IIA
NJAUSS_RS04025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NJAUSS_RS04030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NJAUSS_RS04035	COG1882	Formate acetyltransferase
NJAUSS_RS04055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NJAUSS_RS04060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NJAUSS_RS04065	COG0446	pyridine nucleotide-disulphide oxidoreductase
NJAUSS_RS04075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NJAUSS_RS04080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NJAUSS_RS04085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NJAUSS_RS04090	COG0346	lactoylglutathione lyase activity
NJAUSS_RS04115	COG0210	DNA helicase
NJAUSS_RS04130	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NJAUSS_RS04145	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NJAUSS_RS04160	COG1122	ATPase activity
NJAUSS_RS04165	COG1122	ATPase activity
NJAUSS_RS04170	COG1011	Hydrolase
NJAUSS_RS04200	COG1131	(ABC) transporter
NJAUSS_RS04230	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NJAUSS_RS04235	COG1074	ATP-dependent DNA helicase activity
NJAUSS_RS04245	COG0187	DNA topoisomerase II activity
NJAUSS_RS04270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NJAUSS_RS04280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NJAUSS_RS04300	COG0539	negative regulation of cytoplasmic translation
NJAUSS_RS04325	COG1104	cysteine desulfurase activity
NJAUSS_RS04330	COG0301	tRNA thio-modification
NJAUSS_RS04335	COG1114	Component of the transport system for branched-chain amino acids
NJAUSS_RS04340	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NJAUSS_RS04345	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NJAUSS_RS04365	COG0564	pseudouridine synthase activity
NJAUSS_RS04370	COG2824	Alkylphosphonate utilization operon protein PhnA
NJAUSS_RS04380	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NJAUSS_RS04385	COG0540	Belongs to the ATCase OTCase family
NJAUSS_RS04390	COG0505	Belongs to the CarA family
NJAUSS_RS04400	COG2521	methyltransferase
NJAUSS_RS04400	COG2136	Putative SAM-dependent methyltransferase
NJAUSS_RS04405	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NJAUSS_RS04415	COG0228	four-way junction DNA binding
NJAUSS_RS04430	COG1132	(ABC) transporter
NJAUSS_RS04435	COG0726	polysaccharide deacetylase
NJAUSS_RS04440	COG0460	homoserine dehydrogenase
NJAUSS_RS04445	COG0083	homoserine kinase activity
NJAUSS_RS04450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NJAUSS_RS04455	COG3842	ATPase activity
NJAUSS_RS04460	COG1176	ABC-type spermidine putrescine transport system, permease component I
NJAUSS_RS04465	COG1177	transmembrane transport
NJAUSS_RS04475	COG0038	chloride channel
NJAUSS_RS04490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NJAUSS_RS04495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NJAUSS_RS04510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NJAUSS_RS04515	COG0336	Belongs to the RNA methyltransferase TrmD family
NJAUSS_RS04520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NJAUSS_RS04525	COG1349	DNA-binding transcription factor activity
NJAUSS_RS04530	COG1105	Belongs to the carbohydrate kinase PfkB family
NJAUSS_RS04535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJAUSS_RS04535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NJAUSS_RS04535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NJAUSS_RS04545	COG1307	EDD domain protein, DegV family
NJAUSS_RS04550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NJAUSS_RS04555	COG0617	tRNA 3'-terminal CCA addition
NJAUSS_RS04560	COG0488	(ABC) transporter
NJAUSS_RS04570	COG1940	carbohydrate kinase activity
NJAUSS_RS04585	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NJAUSS_RS04590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NJAUSS_RS04600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NJAUSS_RS04620	COG0481	GTPase activity
NJAUSS_RS04645	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NJAUSS_RS04650	COG2890	protein-(glutamine-N5) methyltransferase activity
NJAUSS_RS04655	COG0009	L-threonylcarbamoyladenylate synthase
NJAUSS_RS04665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NJAUSS_RS04675	COG0741	lytic transglycosylase activity
NJAUSS_RS04680	COG4221	oxidoreductase activity
NJAUSS_RS04705	COG1401	restriction endodeoxyribonuclease activity
NJAUSS_RS04710	COG4268	DNA restriction-modification system
NJAUSS_RS04720	COG2188	Transcriptional regulator
NJAUSS_RS04725	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NJAUSS_RS04730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NJAUSS_RS04745	COG1660	Displays ATPase and GTPase activities
NJAUSS_RS04755	COG4974	Belongs to the 'phage' integrase family
NJAUSS_RS04770	COG0745	RESPONSE REGULATOR receiver
NJAUSS_RS04790	COG1136	(ABC) transporter
NJAUSS_RS04830	COG2382	esterase
NJAUSS_RS04840	COG2207	Transcriptional regulator
NJAUSS_RS04840	COG3708	Transcriptional regulator
NJAUSS_RS04845	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NJAUSS_RS04850	COG0647	UMP catabolic process
NJAUSS_RS04855	COG0222	ribosome binding
NJAUSS_RS04860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NJAUSS_RS04865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NJAUSS_RS04870	COG0758	DNA mediated transformation
NJAUSS_RS04875	COG0110	maltose O-acetyltransferase activity
NJAUSS_RS04880	COG1937	Protein conserved in bacteria
NJAUSS_RS04890	COG0446	pyridine nucleotide-disulphide oxidoreductase
NJAUSS_RS04900	COG1272	protein, Hemolysin III
NJAUSS_RS04910	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NJAUSS_RS04915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NJAUSS_RS04930	COG0737	Belongs to the 5'-nucleotidase family
NJAUSS_RS04940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NJAUSS_RS04945	COG0463	Glycosyl transferase, family 2
NJAUSS_RS04955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NJAUSS_RS04960	COG0284	orotidine-5'-phosphate decarboxylase activity
NJAUSS_RS04965	COG0167	dihydroorotate dehydrogenase activity
NJAUSS_RS04990	COG0297	glycogen (starch) synthase activity
NJAUSS_RS05000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJAUSS_RS05005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJAUSS_RS05020	COG3583	domain protein
NJAUSS_RS05045	COG1126	abc transporter atp-binding protein
NJAUSS_RS05055	COG0488	(ABC) transporter
NJAUSS_RS05060	COG2873	o-acetylhomoserine
NJAUSS_RS05085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NJAUSS_RS05085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NJAUSS_RS05095	COG3711	transcriptional antiterminator
NJAUSS_RS05100	COG3684	Belongs to the aldolase LacD family
NJAUSS_RS05105	COG1105	Belongs to the carbohydrate kinase PfkB family
NJAUSS_RS05110	COG1105	Belongs to the carbohydrate kinase PfkB family
NJAUSS_RS05115	COG0698	ribose 5-phosphate isomerase
NJAUSS_RS05120	COG0698	ribose 5-phosphate isomerase
NJAUSS_RS05130	COG1349	DNA-binding transcription factor activity
NJAUSS_RS05160	COG1396	sequence-specific DNA binding
NJAUSS_RS05165	COG1194	a g-specific adenine glycosylase
NJAUSS_RS05175	COG1132	(ABC) transporter
NJAUSS_RS05180	COG1132	(ABC) transporter
NJAUSS_RS05185	COG0280	phosphate acetyltransferase
NJAUSS_RS05190	COG0564	pseudouridine synthase activity
NJAUSS_RS05195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NJAUSS_RS05200	COG2357	RelA SpoT domain protein
NJAUSS_RS05205	COG4116	CYTH
NJAUSS_RS05215	COG1104	cysteine desulfurase activity
NJAUSS_RS05230	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NJAUSS_RS05235	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NJAUSS_RS05245	COG3764	Sortase (surface protein transpeptidase)
NJAUSS_RS05250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NJAUSS_RS05255	COG0039	L-malate dehydrogenase activity
NJAUSS_RS05260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NJAUSS_RS05265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NJAUSS_RS05270	COG1079	Belongs to the binding-protein-dependent transport system permease family
NJAUSS_RS05275	COG4603	Belongs to the binding-protein-dependent transport system permease family
NJAUSS_RS05280	COG3845	ABC transporter
NJAUSS_RS05285	COG1744	ABC transporter substrate-binding protein PnrA-like
NJAUSS_RS05300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NJAUSS_RS05305	COG2813	Specifically methylates the guanine in position
NJAUSS_RS05310	COG1072	(Pantothenic acid kinase))
NJAUSS_RS05335	COG5002	protein histidine kinase activity
NJAUSS_RS05340	COG0745	RESPONSE REGULATOR receiver
NJAUSS_RS05355	COG0704	Plays a role in the regulation of phosphate uptake
NJAUSS_RS05360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NJAUSS_RS05365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NJAUSS_RS05370	COG0581	inorganic phosphate transmembrane transporter activity
NJAUSS_RS05375	COG0573	inorganic phosphate transmembrane transporter activity
NJAUSS_RS05385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NJAUSS_RS05385	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NJAUSS_RS05390	COG0483	inositol monophosphate 1-phosphatase activity
NJAUSS_RS05395	COG4476	Belongs to the UPF0223 family
NJAUSS_RS05400	COG1393	Belongs to the ArsC family
NJAUSS_RS05405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NJAUSS_RS05410	COG0196	riboflavin kinase activity
NJAUSS_RS05415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NJAUSS_RS05475	COG0561	phosphatase activity
NJAUSS_RS05480	COG2195	Cleaves the N-terminal amino acid of tripeptides
NJAUSS_RS05515	COG3759	membrane
NJAUSS_RS05520	COG1846	Transcriptional regulator
NJAUSS_RS05535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NJAUSS_RS05540	COG2610	gluconate transmembrane transporter activity
NJAUSS_RS05560	COG0302	gtp cyclohydrolase
NJAUSS_RS05565	COG1051	belongs to the nudix hydrolase family
NJAUSS_RS05590	COG0072	phenylalanine-tRNA ligase activity
NJAUSS_RS05590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NJAUSS_RS05620	COG1028	Short-chain dehydrogenase reductase Sdr
NJAUSS_RS05625	COG1312	Catalyzes the dehydration of D-mannonate
NJAUSS_RS05635	COG0800	Aldolase
NJAUSS_RS05645	COG3250	beta-galactosidase activity
NJAUSS_RS05655	COG2211	Major facilitator Superfamily
NJAUSS_RS05670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NJAUSS_RS05680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NJAUSS_RS05685	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NJAUSS_RS05690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NJAUSS_RS05695	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NJAUSS_RS05700	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NJAUSS_RS05705	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NJAUSS_RS05710	COG0356	it plays a direct role in the translocation of protons across the membrane
NJAUSS_RS05720	COG1597	lipid kinase activity
NJAUSS_RS05730	COG0701	Predicted permease
NJAUSS_RS05735	COG3689	TIGRFAM TIGR03943 family protein
NJAUSS_RS05740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NJAUSS_RS05755	COG0552	protein localization to endoplasmic reticulum
NJAUSS_RS05760	COG0561	phosphatase activity
NJAUSS_RS05765	COG0561	phosphatase activity
NJAUSS_RS05770	COG1196	nuclear chromosome segregation
NJAUSS_RS05795	COG2826	transposase and inactivated derivatives, IS30 family
NJAUSS_RS05810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJAUSS_RS05815	COG0538	isocitrate dehydrogenase activity
NJAUSS_RS05820	COG0372	Belongs to the citrate synthase family
NJAUSS_RS05825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NJAUSS_RS05830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NJAUSS_RS05835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NJAUSS_RS05845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NJAUSS_RS05850	COG1609	Transcriptional regulator
NJAUSS_RS05865	COG5492	domain, Protein
NJAUSS_RS05870	COG5492	domain, Protein
NJAUSS_RS05875	COG5492	domain, Protein
NJAUSS_RS05885	COG3716	PTS system mannose fructose sorbose family IID component
NJAUSS_RS05895	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJAUSS_RS05900	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NJAUSS_RS05925	COG1028	Short-chain dehydrogenase reductase Sdr
NJAUSS_RS05960	COG1476	TRANSCRIPTIONal
NJAUSS_RS05985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NJAUSS_RS05995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NJAUSS_RS06000	COG4122	O-methyltransferase activity
NJAUSS_RS06025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NJAUSS_RS06025	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NJAUSS_RS06035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NJAUSS_RS06040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NJAUSS_RS06045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NJAUSS_RS06050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NJAUSS_RS06055	COG1116	anion transmembrane transporter activity
NJAUSS_RS06055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NJAUSS_RS06060	COG4120	Belongs to the binding-protein-dependent transport system permease family
NJAUSS_RS06080	COG3684	Belongs to the aldolase LacD family
NJAUSS_RS06090	COG3679	Belongs to the UPF0342 family
NJAUSS_RS06095	COG0287	Prephenate dehydrogenase
NJAUSS_RS06100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NJAUSS_RS06105	COG0710	3-dehydroquinate dehydratase activity
NJAUSS_RS06110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NJAUSS_RS06115	COG1368	sulfuric ester hydrolase activity
NJAUSS_RS06130	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NJAUSS_RS06140	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NJAUSS_RS06170	COG1216	Glycosyl transferase, family 2
NJAUSS_RS06185	COG1216	Glycosyl transferase, family 2
NJAUSS_RS06185	COG1442	glycosyl transferase family 8
NJAUSS_RS06190	COG1442	glycosyl transferase family 8
NJAUSS_RS06220	COG0463	Glycosyl transferase, family 2
NJAUSS_RS06250	COG1091	dTDP-4-dehydrorhamnose reductase activity
NJAUSS_RS06255	COG1088	dTDP-glucose 4,6-dehydratase activity
NJAUSS_RS06270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NJAUSS_RS06280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NJAUSS_RS06285	COG2384	SAM-dependent methyltransferase
NJAUSS_RS06300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NJAUSS_RS06315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NJAUSS_RS06315	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NJAUSS_RS06320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NJAUSS_RS06330	COG0300	oxidoreductase activity
NJAUSS_RS06335	COG1234	tRNA 3'-trailer cleavage
NJAUSS_RS06345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NJAUSS_RS06350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NJAUSS_RS06360	COG2807	transmembrane transport
NJAUSS_RS06365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NJAUSS_RS06370	COG1702	phosphate starvation-inducible protein PhoH
NJAUSS_RS06375	COG4479	Belongs to the UPF0346 family
NJAUSS_RS06390	COG2996	Protein conserved in bacteria
NJAUSS_RS06395	COG0233	cytoplasmic translational termination
NJAUSS_RS06400	COG0528	UMP kinase activity
NJAUSS_RS06405	COG2244	polysaccharide biosynthetic process
NJAUSS_RS06410	COG0625	glutathione transferase activity
NJAUSS_RS06435	COG0346	lactoylglutathione lyase activity
NJAUSS_RS06440	COG1674	ftsk spoiiie
NJAUSS_RS06440	COG0697	spore germination
NJAUSS_RS06445	COG1621	beta-fructofuranosidase activity
NJAUSS_RS06455	COG0395	ABC-type sugar transport system, permease component
NJAUSS_RS06460	COG4209	transmembrane transport
NJAUSS_RS06465	COG1609	Transcriptional regulator
NJAUSS_RS06485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NJAUSS_RS06500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NJAUSS_RS06510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NJAUSS_RS06520	COG1181	Belongs to the D-alanine--D-alanine ligase family
NJAUSS_RS06525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NJAUSS_RS06530	COG0768	penicillin binding
NJAUSS_RS06540	COG0488	(ABC) transporter
NJAUSS_RS06550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NJAUSS_RS06560	COG0745	RESPONSE REGULATOR receiver
NJAUSS_RS06565	COG1126	abc transporter atp-binding protein
NJAUSS_RS06570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJAUSS_RS06575	COG0765	amino acid transport
NJAUSS_RS06580	COG0765	amino acid transport
NJAUSS_RS06585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NJAUSS_RS06600	COG0438	transferase activity, transferring glycosyl groups
NJAUSS_RS06615	COG1609	Transcriptional regulator
NJAUSS_RS06635	COG3716	PTS system mannose fructose sorbose family IID component
NJAUSS_RS06640	COG3715	PTS system
NJAUSS_RS06645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJAUSS_RS06660	COG1070	Carbohydrate kinase
NJAUSS_RS06665	COG2115	Belongs to the xylose isomerase family
NJAUSS_RS06670	COG1940	carbohydrate kinase activity
NJAUSS_RS06695	COG0343	queuine tRNA-ribosyltransferase activity
NJAUSS_RS06705	COG1832	CoA-binding protein
NJAUSS_RS06715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NJAUSS_RS06715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NJAUSS_RS06730	COG1136	(ABC) transporter
NJAUSS_RS06745	COG2217	Heavy metal translocating P-type atpase
NJAUSS_RS06760	COG1063	alcohol dehydrogenase
NJAUSS_RS06765	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NJAUSS_RS06770	COG0557	exoribonuclease II activity
NJAUSS_RS06780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NJAUSS_RS06785	COG2814	Major facilitator Superfamily
NJAUSS_RS06795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NJAUSS_RS06800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NJAUSS_RS06805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NJAUSS_RS06815	COG1737	Transcriptional regulator
NJAUSS_RS06825	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NJAUSS_RS06835	COG1011	Hydrolase
NJAUSS_RS06840	COG1132	(ABC) transporter
NJAUSS_RS06845	COG1132	(ABC) transporter
NJAUSS_RS06870	COG2177	Part of the ABC transporter FtsEX involved in
NJAUSS_RS06875	COG2884	Cell division ATP-binding protein ftsE
NJAUSS_RS06880	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NJAUSS_RS06885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NJAUSS_RS06910	COG2826	transposase and inactivated derivatives, IS30 family
NJAUSS_RS06940	COG2151	metal-sulfur cluster biosynthetic enzyme
NJAUSS_RS06945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NJAUSS_RS06950	COG0358	DNA primase activity
NJAUSS_RS06955	COG1970	mechanosensitive ion channel activity
NJAUSS_RS06960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NJAUSS_RS06965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NJAUSS_RS06975	COG0647	UMP catabolic process
NJAUSS_RS06980	COG1051	belongs to the nudix hydrolase family
NJAUSS_RS06990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NJAUSS_RS06995	COG0058	SHG alpha-glucan phosphorylase activity
NJAUSS_RS07000	COG0813	purine-nucleoside phosphorylase activity
NJAUSS_RS07005	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NJAUSS_RS07015	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NJAUSS_RS07020	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NJAUSS_RS07025	COG0732	type I restriction modification DNA specificity domain
NJAUSS_RS07045	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NJAUSS_RS07060	COG2268	Band 7 protein
NJAUSS_RS07065	COG1704	LemA family
NJAUSS_RS07075	COG1573	uracil-dna glycosylase
NJAUSS_RS07110	COG2226	methyltransferase
NJAUSS_RS07115	COG0488	(ABC) transporter
NJAUSS_RS07120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NJAUSS_RS07135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NJAUSS_RS07140	COG3442	glutamine amidotransferase
NJAUSS_RS07145	COG2226	methyltransferase
NJAUSS_RS07160	COG0488	(ABC) transporter
NJAUSS_RS07195	COG3842	ATPase activity
NJAUSS_RS07215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJAUSS_RS07215	COG2190	(PTS) system
NJAUSS_RS07215	COG1263	PTS System
NJAUSS_RS07220	COG3711	transcriptional antiterminator
NJAUSS_RS07225	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NJAUSS_RS07230	COG3527	Alpha-acetolactate decarboxylase
NJAUSS_RS07240	COG0628	permease
NJAUSS_RS07245	COG2706	6-phosphogluconolactonase activity
NJAUSS_RS07255	COG1011	Hydrolase
NJAUSS_RS07295	COG0560	Phosphoserine phosphatase
NJAUSS_RS07300	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NJAUSS_RS07305	COG0187	DNA topoisomerase II activity
NJAUSS_RS07310	COG0693	protein deglycase activity
NJAUSS_RS07315	COG0772	Belongs to the SEDS family
NJAUSS_RS07320	COG0582	viral genome integration into host DNA
NJAUSS_RS07405	COG0582	viral genome integration into host DNA
NJAUSS_RS07420	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NJAUSS_RS07425	COG0716	FMN binding
NJAUSS_RS07435	COG1605	Chorismate mutase
NJAUSS_RS07435	COG0287	Prephenate dehydrogenase
NJAUSS_RS07440	COG0038	chloride channel
NJAUSS_RS07450	COG0737	Belongs to the 5'-nucleotidase family
NJAUSS_RS07455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NJAUSS_RS07460	COG1466	dna polymerase III delta subunit
NJAUSS_RS07495	COG0683	leucine binding
NJAUSS_RS07510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NJAUSS_RS07515	COG0366	Alpha amylase catalytic
NJAUSS_RS07525	COG0395	ABC-type sugar transport system, permease component
NJAUSS_RS07530	COG1175	transmembrane transport
NJAUSS_RS07535	COG1653	transport
NJAUSS_RS07545	COG2207	Transcriptional regulator
NJAUSS_RS07550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NJAUSS_RS07555	COG0626	cystathionine gamma-synthase activity
NJAUSS_RS07575	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NJAUSS_RS07580	COG2827	Endonuclease containing a URI domain
NJAUSS_RS07605	COG0640	Transcriptional regulator
NJAUSS_RS07610	COG0513	Belongs to the DEAD box helicase family
NJAUSS_RS07615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NJAUSS_RS07655	COG0494	nUDIX hydrolase
NJAUSS_RS07660	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NJAUSS_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
NJAUSS_RS07705	COG0577	efflux transmembrane transporter activity
NJAUSS_RS07710	COG1136	(ABC) transporter
NJAUSS_RS07715	COG2205	protein histidine kinase activity
NJAUSS_RS07730	COG0436	Aminotransferase
NJAUSS_RS07740	COG1174	glycine betaine transport
NJAUSS_RS07745	COG0517	IMP dehydrogenase activity
NJAUSS_RS07745	COG1125	glycine betaine transport
NJAUSS_RS07765	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NJAUSS_RS07770	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NJAUSS_RS07775	COG1482	cell wall glycoprotein biosynthetic process
NJAUSS_RS07800	COG3091	SprT-like family
NJAUSS_RS07810	COG0656	L-ascorbic acid biosynthetic process
NJAUSS_RS07815	COG4708	membrane
NJAUSS_RS07820	COG2246	polysaccharide biosynthetic process
NJAUSS_RS07830	COG0024	Methionine aminopeptidase
NJAUSS_RS07840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NJAUSS_RS07845	COG2249	NAD(P)H dehydrogenase (quinone) activity
NJAUSS_RS07850	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NJAUSS_RS07855	COG2131	deaminase
NJAUSS_RS07865	COG1363	Peptidase, m42
NJAUSS_RS07880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NJAUSS_RS07885	COG1956	GAF domain-containing protein
NJAUSS_RS07895	COG1695	Transcriptional regulator
NJAUSS_RS07910	COG0513	Belongs to the DEAD box helicase family
NJAUSS_RS07915	COG0726	polysaccharide deacetylase
NJAUSS_RS07935	COG0183	Belongs to the thiolase family
NJAUSS_RS07940	COG3425	synthase
NJAUSS_RS07965	COG0776	regulation of translation
NJAUSS_RS07975	COG2755	lipolytic protein G-D-S-L family
NJAUSS_RS07980	COG1307	EDD domain protein, DegV family
NJAUSS_RS07985	COG0497	DNA recombination
NJAUSS_RS07990	COG1438	arginine binding
NJAUSS_RS07995	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NJAUSS_RS08005	COG1722	exodeoxyribonuclease VII activity
NJAUSS_RS08010	COG1570	exodeoxyribonuclease VII activity
NJAUSS_RS08015	COG2321	neutral zinc metallopeptidase
NJAUSS_RS08020	COG1755	Isoprenylcysteine carboxyl methyltransferase
NJAUSS_RS08025	COG5002	protein histidine kinase activity
NJAUSS_RS08030	COG0745	RESPONSE REGULATOR receiver
NJAUSS_RS08055	COG1227	inorganic diphosphatase activity
NJAUSS_RS08065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NJAUSS_RS08070	COG1253	flavin adenine dinucleotide binding
NJAUSS_RS08075	COG1119	ATPase activity
NJAUSS_RS08080	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NJAUSS_RS08090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NJAUSS_RS08095	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NJAUSS_RS08110	COG4470	Protein conserved in bacteria
NJAUSS_RS08115	COG3480	Lon protease (S16) C-terminal proteolytic domain
NJAUSS_RS08120	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NJAUSS_RS08125	COG0742	ribosomal rna small subunit methyltransferase
NJAUSS_RS08135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NJAUSS_RS08140	COG4483	Protein conserved in bacteria
NJAUSS_RS08145	COG2197	response regulator
NJAUSS_RS08150	COG2203	Gaf domain
NJAUSS_RS08150	COG4585	Histidine kinase
NJAUSS_RS08155	COG0842	Transport permease protein
NJAUSS_RS08160	COG1131	(ABC) transporter
NJAUSS_RS08175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NJAUSS_RS08190	COG0671	phosphoesterase, PA-phosphatase related
NJAUSS_RS08195	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NJAUSS_RS08210	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NJAUSS_RS08215	COG1187	pseudouridine synthase activity
NJAUSS_RS08220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NJAUSS_RS08225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NJAUSS_RS08230	COG0582	viral genome integration into host DNA
NJAUSS_RS08250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NJAUSS_RS08255	COG3763	UPF0154 protein
NJAUSS_RS08265	COG3579	cysteine-type endopeptidase activity
NJAUSS_RS08280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NJAUSS_RS08285	COG1254	Belongs to the acylphosphatase family
NJAUSS_RS08295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NJAUSS_RS08300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NJAUSS_RS08310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NJAUSS_RS08320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NJAUSS_RS08335	COG1160	GTP binding
NJAUSS_RS08345	COG1484	DNA-dependent DNA replication
NJAUSS_RS08355	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NJAUSS_RS08360	COG0628	permease
NJAUSS_RS08365	COG0745	RESPONSE REGULATOR receiver
NJAUSS_RS08370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NJAUSS_RS08380	COG0492	ferredoxin-NADP+ reductase activity
NJAUSS_RS08390	COG0513	Belongs to the DEAD box helicase family
NJAUSS_RS08400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NJAUSS_RS08405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NJAUSS_RS08410	COG0768	penicillin binding
NJAUSS_RS08420	COG0275	rRNA processing
NJAUSS_RS08470	COG4939	FMN-binding domain protein
NJAUSS_RS08475	COG0142	geranyltranstransferase activity
NJAUSS_RS08480	COG1252	NADH dehydrogenase
NJAUSS_RS08490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NJAUSS_RS08495	COG0569	domain protein
NJAUSS_RS08500	COG0534	Mate efflux family protein
NJAUSS_RS08510	COG4224	UPF0291 protein
NJAUSS_RS08515	COG0751	glycine-tRNA ligase activity
NJAUSS_RS08540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NJAUSS_RS08545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NJAUSS_RS08550	COG1464	Belongs to the NlpA lipoprotein family
NJAUSS_RS08555	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NJAUSS_RS08560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NJAUSS_RS08565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NJAUSS_RS08570	COG2252	PERMEase
NJAUSS_RS08575	COG0561	phosphatase activity
NJAUSS_RS08585	COG3715	PTS system
NJAUSS_RS08590	COG3716	PTS system mannose fructose sorbose family IID component
NJAUSS_RS08615	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NJAUSS_RS08660	COG0439	Biotin carboxylase
NJAUSS_RS08680	COG1028	Short-chain dehydrogenase reductase Sdr
NJAUSS_RS08685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NJAUSS_RS08690	COG2070	2-Nitropropane dioxygenase
NJAUSS_RS08700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NJAUSS_RS08710	COG1024	Enoyl-CoA hydratase
NJAUSS_RS08715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NJAUSS_RS08720	COG0527	aspartate kinase activity
NJAUSS_RS08730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NJAUSS_RS08735	COG0736	holo-[acyl-carrier-protein] synthase activity
NJAUSS_RS08740	COG0653	protein targeting
NJAUSS_RS08750	COG1940	carbohydrate kinase activity
NJAUSS_RS08755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJAUSS_RS08755	COG2190	(PTS) system
NJAUSS_RS08755	COG1263	PTS System
NJAUSS_RS08760	COG1621	beta-fructofuranosidase activity
NJAUSS_RS08765	COG1609	Transcriptional regulator
NJAUSS_RS08770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NJAUSS_RS08785	COG0006	proline dipeptidase activity
NJAUSS_RS08790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NJAUSS_RS08810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NJAUSS_RS08815	COG0629	single-stranded DNA binding
NJAUSS_RS08825	COG2826	transposase and inactivated derivatives, IS30 family
NJAUSS_RS08830	COG0095	Lipoate-protein ligase
NJAUSS_RS08845	COG0508	dehydrogenase complex catalyzes the overall conversion of
NJAUSS_RS08850	COG0022	dehydrogenase e1 component
NJAUSS_RS08850	COG0508	dehydrogenase complex catalyzes the overall conversion of
NJAUSS_RS08855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NJAUSS_RS08860	COG2860	membrane
NJAUSS_RS08875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NJAUSS_RS08880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NJAUSS_RS08890	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NJAUSS_RS08895	COG0195	Participates in both transcription termination and antitermination
NJAUSS_RS08905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NJAUSS_RS08915	COG4473	ABC transporter
NJAUSS_RS08920	COG1131	(ABC) transporter
NJAUSS_RS08925	COG0537	adenosine 5'-monophosphoramidase activity
NJAUSS_RS08935	COG1316	TRANSCRIPTIONal
NJAUSS_RS08945	COG0802	atpase or kinase
NJAUSS_RS08950	COG1461	Dihydroxyacetone kinase
NJAUSS_RS08965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NJAUSS_RS08970	COG0601	transmembrane transport
NJAUSS_RS08975	COG4608	Belongs to the ABC transporter superfamily
NJAUSS_RS08990	COG1686	Belongs to the peptidase S11 family
NJAUSS_RS09005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NJAUSS_RS09010	COG0719	Fe-S assembly protein
NJAUSS_RS09020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NJAUSS_RS09025	COG4862	establishment of competence for transformation
NJAUSS_RS09030	COG1968	undecaprenyl-diphosphatase activity
NJAUSS_RS09035	COG0765	amino acid transport
NJAUSS_RS09055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NJAUSS_RS09060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NJAUSS_RS09065	COG0440	acetolactate synthase activity
NJAUSS_RS09070	COG0028	Belongs to the TPP enzyme family
NJAUSS_RS09090	COG0129	dihydroxy-acid dehydratase activity
NJAUSS_RS09100	COG2151	metal-sulfur cluster biosynthetic enzyme
NJAUSS_RS09120	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NJAUSS_RS09135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NJAUSS_RS09160	COG3842	ATPase activity
NJAUSS_RS09170	COG4753	response regulator
NJAUSS_RS09170	COG2207	Transcriptional regulator
NJAUSS_RS09175	COG2972	Histidine kinase
NJAUSS_RS09190	COG1653	transport
NJAUSS_RS09195	COG0395	ABC-type sugar transport system, permease component
NJAUSS_RS09200	COG1175	transmembrane transport
NJAUSS_RS09215	COG0383	alpha-mannosidase activity
NJAUSS_RS09235	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NJAUSS_RS09255	COG1045	serine acetyltransferase
NJAUSS_RS09260	COG1185	polyribonucleotide nucleotidyltransferase activity
NJAUSS_RS09275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJAUSS_RS09275	COG1263	PTS System
NJAUSS_RS09285	COG1737	Transcriptional regulator
NJAUSS_RS09290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NJAUSS_RS09310	COG1187	pseudouridine synthase activity
NJAUSS_RS09330	COG0242	peptide deformylase activity
NJAUSS_RS09340	COG0066	3-isopropylmalate dehydratase activity
NJAUSS_RS09365	COG2309	aminopeptidase activity
NJAUSS_RS09380	COG2176	DNA-directed DNA polymerase activity
NJAUSS_RS09385	COG2376	Dihydroxyacetone kinase
NJAUSS_RS09395	COG2376	Dihydroxyacetone kinase
NJAUSS_RS09400	COG1461	Dihydroxyacetone kinase
NJAUSS_RS09405	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NJAUSS_RS09410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NJAUSS_RS09415	COG0442	prolyl-tRNA aminoacylation
NJAUSS_RS09425	COG4589	Belongs to the CDS family
NJAUSS_RS09430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NJAUSS_RS09435	COG1862	Preprotein translocase
NJAUSS_RS09445	COG2918	glutathione biosynthetic process
NJAUSS_RS09445	COG1181	Belongs to the D-alanine--D-alanine ligase family
NJAUSS_RS09455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NJAUSS_RS09460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NJAUSS_RS09470	COG3201	nicotinamide mononucleotide transporter
NJAUSS_RS09475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NJAUSS_RS09485	COG4463	regulation of RNA biosynthetic process
NJAUSS_RS09500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NJAUSS_RS09535	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NJAUSS_RS09540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NJAUSS_RS09545	COG0492	ferredoxin-NADP+ reductase activity
NJAUSS_RS09550	COG0564	pseudouridine synthase activity
NJAUSS_RS09555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NJAUSS_RS09575	COG1564	THIamine pyrophosphokinase
NJAUSS_RS09585	COG1162	GTPase activity
NJAUSS_RS09635	COG4115	mRNA cleavage
NJAUSS_RS09670	COG0084	hydrolase, TatD family'
NJAUSS_RS09680	COG1847	R3H domain protein
NJAUSS_RS09690	COG0594	ribonuclease P activity
NJAUSS_RS09695	COG0165	Argininosuccinate lyase
NJAUSS_RS09700	COG0137	argininosuccinate synthase activity
NJAUSS_RS09710	COG1827	regulation of RNA biosynthetic process
NJAUSS_RS09725	COG2040	homocysteine
NJAUSS_RS09730	COG0833	amino acid
NJAUSS_RS09775	COG0756	dUTP diphosphatase activity
NJAUSS_RS09780	COG1132	(ABC) transporter
NJAUSS_RS09785	COG1132	(ABC) transporter
NJAUSS_RS09795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NJAUSS_RS09800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NJAUSS_RS09805	COG0705	Rhomboid family
NJAUSS_RS09810	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NJAUSS_RS09815	COG1473	amidohydrolase
NJAUSS_RS09820	COG2171	N-acyltransferase activity
NJAUSS_RS09835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NJAUSS_RS09855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NJAUSS_RS09880	COG3623	hexulose-6-phosphate isomerase
NJAUSS_RS09905	COG1523	belongs to the glycosyl hydrolase 13 family
NJAUSS_RS09910	COG1609	Transcriptional regulator
NJAUSS_RS09915	COG1126	abc transporter atp-binding protein
NJAUSS_RS09920	COG0765	amino acid transport
NJAUSS_RS09925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJAUSS_RS09930	COG3942	CHAP domain
NJAUSS_RS09935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NJAUSS_RS09945	COG1447	Phosphotransferase system cellobiose-specific component IIA
NJAUSS_RS09955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJAUSS_RS09955	COG3711	transcriptional antiterminator
NJAUSS_RS09970	COG1486	melibiose metabolic process
NJAUSS_RS09980	COG3590	peptidase
NJAUSS_RS09985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NJAUSS_RS09990	COG1321	iron dependent repressor
NJAUSS_RS09990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NJAUSS_RS09995	COG1121	(ABC) transporter
NJAUSS_RS10005	COG0803	Belongs to the bacterial solute-binding protein 9 family
NJAUSS_RS10040	COG1490	D-aminoacyl-tRNA deacylase activity
NJAUSS_RS10050	COG0737	Belongs to the 5'-nucleotidase family
NJAUSS_RS10105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NJAUSS_RS10130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NJAUSS_RS10155	COG0737	Belongs to the 5'-nucleotidase family
NJAUSS_RS10165	COG1328	CTP reductase activity
NJAUSS_RS10200	COG1438	arginine binding
NJAUSS_RS10205	COG0018	arginyl-trna synthetase
NJAUSS_RS10225	COG1640	4-alpha-glucanotransferase
NJAUSS_RS10230	COG2182	Extracellular solute-binding protein
NJAUSS_RS10235	COG1175	transmembrane transport
NJAUSS_RS10240	COG3833	ABC-type maltose transport systems, permease component
NJAUSS_RS10245	COG5521	maltodextrose utilization protein MalA
NJAUSS_RS10250	COG1609	Transcriptional regulator
NJAUSS_RS10255	COG1523	belongs to the glycosyl hydrolase 13 family
NJAUSS_RS10260	COG1780	Probably involved in ribonucleotide reductase function
NJAUSS_RS10265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NJAUSS_RS10270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NJAUSS_RS10275	COG2153	protein acetylation
NJAUSS_RS10280	COG4989	oxidoreductase activity
NJAUSS_RS10285	COG1216	Glycosyl transferase, family 2
NJAUSS_RS10290	COG1472	Belongs to the glycosyl hydrolase 3 family
NJAUSS_RS10330	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NJAUSS_RS10345	COG0305	Participates in initiation and elongation during chromosome replication
NJAUSS_RS10350	COG0359	binds to the 23S rRNA
NJAUSS_RS10360	COG0445	tRNA wobble uridine modification
NJAUSS_RS10375	COG1051	belongs to the nudix hydrolase family
NJAUSS_RS10380	COG1733	regulation of RNA biosynthetic process
NJAUSS_RS10390	COG0482	sulfurtransferase activity
NJAUSS_RS10395	COG1760	l-serine dehydratase
NJAUSS_RS10400	COG1760	l-serine dehydratase
NJAUSS_RS10410	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NJAUSS_RS10415	COG1122	ATPase activity
NJAUSS_RS10420	COG1122	ATPase activity
NJAUSS_RS10425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NJAUSS_RS10430	COG1426	Protein conserved in bacteria
NJAUSS_RS10435	COG0612	Peptidase, M16
NJAUSS_RS10440	COG0612	Peptidase, M16
NJAUSS_RS10450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NJAUSS_RS10455	COG0516	GMP reductase activity
NJAUSS_RS10455	COG0517	IMP dehydrogenase activity
NJAUSS_RS10465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NJAUSS_RS10470	COG0488	(ABC) transporter
NJAUSS_RS10500	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NJAUSS_RS10505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NJAUSS_RS10510	COG1475	DNA binding
NJAUSS_RS10520	COG0582	viral genome integration into host DNA