locus-tag	class	description
DP111_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DP111_RS00010	COG0592	DNA-directed DNA polymerase activity
DP111_RS00030	COG0012	GTP binding
DP111_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
DP111_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DP111_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DP111_RS00065	COG0037	tRNA processing
DP111_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DP111_RS00190	COG1792	Involved in formation and maintenance of cell shape
DP111_RS00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DP111_RS00210	COG0436	Aminotransferase
DP111_RS00215	COG1381	Involved in DNA repair and RecF pathway recombination
DP111_RS00220	COG0416	fatty acid biosynthetic process
DP111_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DP111_RS00230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DP111_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DP111_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DP111_RS00255	COG0138	bifunctional purine biosynthesis protein purh
DP111_RS00280	COG0151	Belongs to the GarS family
DP111_RS00285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DP111_RS00300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DP111_RS00330	COG1131	(ABC) transporter
DP111_RS00340	COG1132	(ABC) transporter
DP111_RS00345	COG2255	four-way junction helicase activity
DP111_RS00350	COG0546	phosphoglycolate phosphatase activity
DP111_RS00375	COG0285	dihydrofolate synthase activity
DP111_RS00390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DP111_RS00395	COG0632	four-way junction helicase activity
DP111_RS00400	COG0519	Catalyzes the synthesis of GMP from XMP
DP111_RS00415	COG1393	Belongs to the ArsC family
DP111_RS00420	COG4472	Bacterial protein of unknown function (DUF965)
DP111_RS00425	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DP111_RS00430	COG3906	Belongs to the UPF0473 family
DP111_RS00435	COG0051	transcription antitermination factor activity, RNA binding
DP111_RS00440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DP111_RS00445	COG0088	Forms part of the polypeptide exit tunnel
DP111_RS00450	COG0089	rRNA binding
DP111_RS00455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DP111_RS00460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DP111_RS00465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DP111_RS00470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DP111_RS00475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DP111_RS00480	COG0255	Belongs to the universal ribosomal protein uL29 family
DP111_RS00485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DP111_RS00490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DP111_RS00495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DP111_RS00500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DP111_RS00505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DP111_RS00510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DP111_RS00515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DP111_RS00520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DP111_RS00525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DP111_RS00530	COG1841	ribosomal large subunit assembly
DP111_RS00540	COG0201	protein transport
DP111_RS00545	COG0563	adenylate kinase activity
DP111_RS00550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DP111_RS00555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DP111_RS00560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DP111_RS00570	COG0202	RNA polymerase activity
DP111_RS00685	COG0582	viral genome integration into host DNA
DP111_RS00695	COG2946	Replication initiation factor
DP111_RS00705	COG1674	ftsk spoiiie
DP111_RS00740	COG1121	(ABC) transporter
DP111_RS00745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP111_RS00750	COG3443	Belongs to the bacterial solute-binding protein 9 family
DP111_RS00750	COG0803	Belongs to the bacterial solute-binding protein 9 family
DP111_RS00755	COG3682	Transcriptional regulator
DP111_RS00785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP111_RS00790	COG0085	RNA polymerase activity
DP111_RS00795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DP111_RS00805	COG1619	proteins homologs of microcin C7 resistance protein MccF
DP111_RS00810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DP111_RS00815	COG1459	type II secretion system
DP111_RS00820	COG4537	Required for transformation and DNA binding
DP111_RS00850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DP111_RS00860	COG0285	dihydrofolate synthase activity
DP111_RS00865	COG1363	Peptidase, m42
DP111_RS00875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP111_RS00885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP111_RS00915	COG0459	protein refolding
DP111_RS00925	COG0049	tRNA binding
DP111_RS00930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DP111_RS00935	COG3590	peptidase
DP111_RS00945	COG0126	phosphoglycerate kinase activity
DP111_RS00955	COG0789	Transcriptional regulator
DP111_RS00960	COG0174	glutamine synthetase
DP111_RS00985	COG1214	PFAM Peptidase M22, glycoprotease
DP111_RS00995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DP111_RS01000	COG2207	Transcriptional regulator
DP111_RS01010	COG1175	transmembrane transport
DP111_RS01015	COG0395	ABC-type sugar transport system, permease component
DP111_RS01055	COG1131	(ABC) transporter
DP111_RS01060	COG2081	HI0933 family
DP111_RS01065	COG2723	6-phospho-beta-galactosidase activity
DP111_RS01075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP111_RS01090	COG3959	Transketolase, thiamine diphosphate binding domain
DP111_RS01095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DP111_RS01100	COG0584	glycerophosphoryl diester phosphodiesterase
DP111_RS01105	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DP111_RS01110	COG2222	sugar isomerase
DP111_RS01140	COG1882	Formate acetyltransferase
DP111_RS01155	COG2910	NAD(P)H-binding
DP111_RS01180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP111_RS01215	COG0363	glucosamine-6-phosphate deaminase activity
DP111_RS01220	COG2217	Heavy metal translocating P-type atpase
DP111_RS01230	COG2217	Heavy metal translocating P-type atpase
DP111_RS01235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DP111_RS01240	COG0681	Belongs to the peptidase S26 family
DP111_RS01260	COG0366	Alpha amylase catalytic
DP111_RS01265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP111_RS01265	COG1263	PTS System
DP111_RS01270	COG2188	Transcriptional regulator
DP111_RS01285	COG1193	negative regulation of DNA recombination
DP111_RS01295	COG3118	belongs to the thioredoxin family
DP111_RS01305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DP111_RS01305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DP111_RS01330	COG1115	amino acid carrier protein
DP111_RS01335	COG0668	transmembrane transport
DP111_RS01350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DP111_RS01360	COG0167	dihydroorotate dehydrogenase activity
DP111_RS01365	COG2843	Capsule synthesis protein
DP111_RS01390	COG0561	phosphatase activity
DP111_RS01405	COG1131	(ABC) transporter
DP111_RS01410	COG1309	transcriptional regulator
DP111_RS01415	COG1511	domain protein
DP111_RS01440	COG1346	cytolysis
DP111_RS01445	COG2116	formate transmembrane transporter activity
DP111_RS01450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP111_RS01455	COG0433	COG0433 Predicted ATPase
DP111_RS01460	COG0494	nUDIX hydrolase
DP111_RS01485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DP111_RS01490	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DP111_RS01505	COG0124	histidyl-tRNA synthetase
DP111_RS01510	COG1064	alcohol dehydrogenase
DP111_RS01515	COG1454	alcohol dehydrogenase
DP111_RS01515	COG1012	belongs to the aldehyde dehydrogenase family
DP111_RS01525	COG4988	ABC transporter
DP111_RS01530	COG1132	(ABC) transporter
DP111_RS01545	COG1129	ABC transporter
DP111_RS01550	COG0534	Mate efflux family protein
DP111_RS01555	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DP111_RS01570	COG1304	FMN binding
DP111_RS01575	COG1132	(ABC) transporter
DP111_RS01580	COG1132	(ABC) transporter
DP111_RS01585	COG3830	Belongs to the UPF0237 family
DP111_RS01590	COG2848	UPF0210 protein
DP111_RS01595	COG0588	phosphoglycerate mutase activity
DP111_RS01600	COG1420	regulation of RNA biosynthetic process
DP111_RS01605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DP111_RS01610	COG0443	Heat shock 70 kDa protein
DP111_RS01615	COG0484	heat shock protein binding
DP111_RS01620	COG0095	Lipoate-protein ligase
DP111_RS01630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP111_RS01635	COG0765	amino acid transport
DP111_RS01660	COG2217	Heavy metal translocating P-type atpase
DP111_RS01685	COG4475	Protein of unknown function (DUF436)
DP111_RS01715	COG4221	oxidoreductase activity
DP111_RS01720	COG0446	pyridine nucleotide-disulphide oxidoreductase
DP111_RS01720	COG1902	pentaerythritol trinitrate reductase activity
DP111_RS01725	COG2910	NAD(P)H-binding
DP111_RS01730	COG1959	2 iron, 2 sulfur cluster binding
DP111_RS01755	COG0544	peptidyl-prolyl cis-trans isomerase activity
DP111_RS01775	COG3343	RNA polymerase activity
DP111_RS01780	COG0504	CTP synthase activity
DP111_RS01790	COG0191	fructose-bisphosphate aldolase activity
DP111_RS01795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DP111_RS01835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DP111_RS01855	COG0589	response to stress
DP111_RS01860	COG0436	Aminotransferase
DP111_RS01865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DP111_RS01870	COG1335	isochorismatase
DP111_RS01875	COG0335	large ribosomal subunit rRNA binding
DP111_RS01920	COG1131	(ABC) transporter
DP111_RS01925	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DP111_RS01935	COG1185	polyribonucleotide nucleotidyltransferase activity
DP111_RS01940	COG1045	serine acetyltransferase
DP111_RS01960	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DP111_RS01985	COG0383	alpha-mannosidase activity
DP111_RS02000	COG1175	transmembrane transport
DP111_RS02005	COG0395	ABC-type sugar transport system, permease component
DP111_RS02010	COG1653	transport
DP111_RS02025	COG2972	Histidine kinase
DP111_RS02030	COG2207	Transcriptional regulator
DP111_RS02030	COG4753	response regulator
DP111_RS02040	COG3842	ATPase activity
DP111_RS02065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP111_RS02085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DP111_RS02175	COG2151	metal-sulfur cluster biosynthetic enzyme
DP111_RS02185	COG0129	dihydroxy-acid dehydratase activity
DP111_RS02200	COG0463	Glycosyl transferase, family 2
DP111_RS02205	COG0028	Belongs to the TPP enzyme family
DP111_RS02210	COG0440	acetolactate synthase activity
DP111_RS02215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DP111_RS02220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DP111_RS02235	COG1126	abc transporter atp-binding protein
DP111_RS02240	COG0765	amino acid transport
DP111_RS02245	COG1968	undecaprenyl-diphosphatase activity
DP111_RS02250	COG4862	establishment of competence for transformation
DP111_RS02255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DP111_RS02265	COG0719	Fe-S assembly protein
DP111_RS02270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DP111_RS02285	COG1686	Belongs to the peptidase S11 family
DP111_RS02290	COG0747	negative chemotaxis
DP111_RS02300	COG4608	Belongs to the ABC transporter superfamily
DP111_RS02305	COG0601	transmembrane transport
DP111_RS02310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DP111_RS02325	COG0802	atpase or kinase
DP111_RS02335	COG1316	TRANSCRIPTIONal
DP111_RS02345	COG0537	adenosine 5'-monophosphoramidase activity
DP111_RS02350	COG1131	(ABC) transporter
DP111_RS02355	COG4473	ABC transporter
DP111_RS02365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DP111_RS02375	COG0195	Participates in both transcription termination and antitermination
DP111_RS02380	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DP111_RS02390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DP111_RS02395	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DP111_RS02410	COG2860	membrane
DP111_RS02415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DP111_RS02420	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP111_RS02420	COG0022	dehydrogenase e1 component
DP111_RS02425	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP111_RS02445	COG2190	(PTS) system
DP111_RS02445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP111_RS02445	COG1263	PTS System
DP111_RS02460	COG1917	Cupin 2, conserved barrel domain protein
DP111_RS02460	COG2207	Transcriptional regulator
DP111_RS02465	COG2723	6-phospho-beta-galactosidase activity
DP111_RS02470	COG0346	lactoylglutathione lyase activity
DP111_RS02475	COG2723	6-phospho-beta-galactosidase activity
DP111_RS02480	COG4095	Psort location CytoplasmicMembrane, score
DP111_RS02495	COG3711	transcriptional antiterminator
DP111_RS02495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP111_RS02500	COG1447	Phosphotransferase system cellobiose-specific component IIA
DP111_RS02510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP111_RS02515	COG2723	6-phospho-beta-galactosidase activity
DP111_RS02525	COG2723	6-phospho-beta-galactosidase activity
DP111_RS02530	COG0095	Lipoate-protein ligase
DP111_RS02540	COG0629	single-stranded DNA binding
DP111_RS02545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DP111_RS02560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DP111_RS02565	COG0006	proline dipeptidase activity
DP111_RS02580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP111_RS02585	COG1609	Transcriptional regulator
DP111_RS02590	COG1621	beta-fructofuranosidase activity
DP111_RS02595	COG2190	(PTS) system
DP111_RS02595	COG1263	PTS System
DP111_RS02595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP111_RS02600	COG1940	carbohydrate kinase activity
DP111_RS02610	COG0653	protein targeting
DP111_RS02615	COG0736	holo-[acyl-carrier-protein] synthase activity
DP111_RS02620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DP111_RS02625	COG0527	aspartate kinase activity
DP111_RS02630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP111_RS02635	COG1024	Enoyl-CoA hydratase
DP111_RS02645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DP111_RS02655	COG2070	2-Nitropropane dioxygenase
DP111_RS02660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DP111_RS02665	COG1028	Short-chain dehydrogenase reductase Sdr
DP111_RS02685	COG0439	Biotin carboxylase
DP111_RS02730	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DP111_RS02755	COG3716	PTS system mannose fructose sorbose family IID component
DP111_RS02760	COG3715	PTS system
DP111_RS02770	COG0561	phosphatase activity
DP111_RS02775	COG2252	PERMEase
DP111_RS02785	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DP111_RS02790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DP111_RS02795	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP111_RS02800	COG1464	Belongs to the NlpA lipoprotein family
DP111_RS02805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DP111_RS02810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DP111_RS02835	COG0751	glycine-tRNA ligase activity
DP111_RS02845	COG4224	UPF0291 protein
DP111_RS02855	COG0534	Mate efflux family protein
DP111_RS02860	COG0569	domain protein
DP111_RS02865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DP111_RS02880	COG1252	NADH dehydrogenase
DP111_RS02885	COG0142	geranyltranstransferase activity
DP111_RS02890	COG4939	FMN-binding domain protein
DP111_RS02935	COG0275	rRNA processing
DP111_RS02945	COG0768	penicillin binding
DP111_RS02950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DP111_RS02975	COG0513	Belongs to the DEAD box helicase family
DP111_RS02985	COG0492	ferredoxin-NADP+ reductase activity
DP111_RS02995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DP111_RS03000	COG0745	RESPONSE REGULATOR receiver
DP111_RS03005	COG0628	permease
DP111_RS03010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DP111_RS03020	COG1484	DNA-dependent DNA replication
DP111_RS03030	COG1160	GTP binding
DP111_RS03045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DP111_RS03055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DP111_RS03065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DP111_RS03070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DP111_RS03075	COG0706	membrane insertase activity
DP111_RS03080	COG1254	Belongs to the acylphosphatase family
DP111_RS03085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP111_RS03105	COG3579	cysteine-type endopeptidase activity
DP111_RS03115	COG3763	UPF0154 protein
DP111_RS03120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DP111_RS03140	COG0582	viral genome integration into host DNA
DP111_RS03145	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DP111_RS03150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DP111_RS03155	COG1187	pseudouridine synthase activity
DP111_RS03175	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DP111_RS03180	COG0671	phosphoesterase, PA-phosphatase related
DP111_RS03185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DP111_RS03185	COG2755	lipolytic protein G-D-S-L family
DP111_RS03195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP111_RS03210	COG1131	(ABC) transporter
DP111_RS03215	COG0842	Transport permease protein
DP111_RS03220	COG4585	Histidine kinase
DP111_RS03225	COG2197	response regulator
DP111_RS03230	COG4483	Protein conserved in bacteria
DP111_RS03235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DP111_RS03245	COG0742	ribosomal rna small subunit methyltransferase
DP111_RS03250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DP111_RS03255	COG3480	Lon protease (S16) C-terminal proteolytic domain
DP111_RS03260	COG4470	Protein conserved in bacteria
DP111_RS03275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DP111_RS03280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DP111_RS03285	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DP111_RS03290	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DP111_RS03295	COG1119	ATPase activity
DP111_RS03300	COG1253	flavin adenine dinucleotide binding
DP111_RS03305	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DP111_RS03315	COG1227	inorganic diphosphatase activity
DP111_RS03335	COG0745	RESPONSE REGULATOR receiver
DP111_RS03340	COG5002	protein histidine kinase activity
DP111_RS03345	COG1755	Isoprenylcysteine carboxyl methyltransferase
DP111_RS03350	COG2321	neutral zinc metallopeptidase
DP111_RS03355	COG1570	exodeoxyribonuclease VII activity
DP111_RS03360	COG1722	exodeoxyribonuclease VII activity
DP111_RS03370	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DP111_RS03375	COG1438	arginine binding
DP111_RS03380	COG0497	DNA recombination
DP111_RS03385	COG1307	EDD domain protein, DegV family
DP111_RS03390	COG2755	lipolytic protein G-D-S-L family
DP111_RS03400	COG0776	regulation of translation
DP111_RS03420	COG3425	synthase
DP111_RS03425	COG0183	Belongs to the thiolase family
DP111_RS03440	COG0726	polysaccharide deacetylase
DP111_RS03445	COG0513	Belongs to the DEAD box helicase family
DP111_RS03450	COG0673	inositol 2-dehydrogenase activity
DP111_RS03460	COG1695	Transcriptional regulator
DP111_RS03470	COG1956	GAF domain-containing protein
DP111_RS03475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DP111_RS03490	COG1363	Peptidase, m42
DP111_RS03500	COG2131	deaminase
DP111_RS03505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DP111_RS03510	COG2249	NAD(P)H dehydrogenase (quinone) activity
DP111_RS03515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DP111_RS03525	COG0024	Methionine aminopeptidase
DP111_RS03535	COG2246	polysaccharide biosynthetic process
DP111_RS03540	COG4708	membrane
DP111_RS03545	COG0656	L-ascorbic acid biosynthetic process
DP111_RS03550	COG2183	response to ionizing radiation
DP111_RS03555	COG3091	SprT-like family
DP111_RS03570	COG1482	cell wall glycoprotein biosynthetic process
DP111_RS03575	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DP111_RS03580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DP111_RS03600	COG0517	IMP dehydrogenase activity
DP111_RS03600	COG1125	glycine betaine transport
DP111_RS03605	COG1174	glycine betaine transport
DP111_RS03615	COG0436	Aminotransferase
DP111_RS03625	COG0745	RESPONSE REGULATOR receiver
DP111_RS03630	COG2205	protein histidine kinase activity
DP111_RS03635	COG1136	(ABC) transporter
DP111_RS03640	COG0577	efflux transmembrane transporter activity
DP111_RS03670	COG1028	Short-chain dehydrogenase reductase Sdr
DP111_RS03685	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DP111_RS03690	COG0494	nUDIX hydrolase
DP111_RS03735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP111_RS03745	COG0513	Belongs to the DEAD box helicase family
DP111_RS03750	COG0640	Transcriptional regulator
DP111_RS03775	COG2827	Endonuclease containing a URI domain
DP111_RS03780	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DP111_RS03800	COG0626	cystathionine gamma-synthase activity
DP111_RS03805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DP111_RS03810	COG2207	Transcriptional regulator
DP111_RS03820	COG1653	transport
DP111_RS03825	COG1175	transmembrane transport
DP111_RS03830	COG0395	ABC-type sugar transport system, permease component
DP111_RS03840	COG0366	Alpha amylase catalytic
DP111_RS03845	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DP111_RS03860	COG0683	leucine binding
DP111_RS03895	COG1466	dna polymerase III delta subunit
DP111_RS03900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DP111_RS03905	COG0737	Belongs to the 5'-nucleotidase family
DP111_RS03915	COG0038	chloride channel
DP111_RS03920	COG0287	Prephenate dehydrogenase
DP111_RS03920	COG1605	Chorismate mutase
DP111_RS03930	COG0716	FMN binding
DP111_RS03935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DP111_RS03950	COG0772	Belongs to the SEDS family
DP111_RS03955	COG0693	protein deglycase activity
DP111_RS03960	COG0187	DNA topoisomerase II activity
DP111_RS03965	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DP111_RS03970	COG0560	Phosphoserine phosphatase
DP111_RS04000	COG1011	Hydrolase
DP111_RS04010	COG2706	6-phosphogluconolactonase activity
DP111_RS04015	COG0628	permease
DP111_RS04025	COG3527	Alpha-acetolactate decarboxylase
DP111_RS04030	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DP111_RS04035	COG3711	transcriptional antiterminator
DP111_RS04040	COG1263	PTS System
DP111_RS04040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP111_RS04040	COG2190	(PTS) system
DP111_RS04060	COG3842	ATPase activity
DP111_RS04095	COG0488	(ABC) transporter
DP111_RS04105	COG2226	methyltransferase
DP111_RS04115	COG3442	glutamine amidotransferase
DP111_RS04120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DP111_RS04135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DP111_RS04140	COG0488	(ABC) transporter
DP111_RS04150	COG2226	methyltransferase
DP111_RS04170	COG1573	uracil-dna glycosylase
DP111_RS04180	COG1704	LemA family
DP111_RS04185	COG2268	Band 7 protein
DP111_RS04200	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DP111_RS04225	COG4974	Belongs to the 'phage' integrase family
DP111_RS04230	COG0732	type I restriction modification DNA specificity domain
DP111_RS04235	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DP111_RS04240	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DP111_RS04250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DP111_RS04255	COG0813	purine-nucleoside phosphorylase activity
DP111_RS04260	COG0058	SHG alpha-glucan phosphorylase activity
DP111_RS04270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP111_RS04280	COG1051	belongs to the nudix hydrolase family
DP111_RS04285	COG0647	UMP catabolic process
DP111_RS04295	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DP111_RS04300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DP111_RS04305	COG1970	mechanosensitive ion channel activity
DP111_RS04310	COG0358	DNA primase activity
DP111_RS04315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DP111_RS04320	COG2151	metal-sulfur cluster biosynthetic enzyme
DP111_RS04355	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DP111_RS04365	COG1131	(ABC) transporter
DP111_RS04370	COG2188	Transcriptional regulator
DP111_RS04380	COG0205	6-phosphofructokinase activity
DP111_RS04385	COG0469	pyruvate kinase activity
DP111_RS04395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DP111_RS04400	COG2755	lipolytic protein G-D-S-L family
DP111_RS04400	COG0657	acetylesterase activity
DP111_RS04415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DP111_RS04430	COG1307	EDD domain protein, DegV family
DP111_RS04435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DP111_RS04440	COG0617	tRNA 3'-terminal CCA addition
DP111_RS04445	COG0488	(ABC) transporter
DP111_RS04455	COG1940	carbohydrate kinase activity
DP111_RS04470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DP111_RS04475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DP111_RS04485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DP111_RS04500	COG0481	GTPase activity
DP111_RS04525	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DP111_RS04530	COG2890	protein-(glutamine-N5) methyltransferase activity
DP111_RS04535	COG0009	L-threonylcarbamoyladenylate synthase
DP111_RS04545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DP111_RS04555	COG0741	lytic transglycosylase activity
DP111_RS04560	COG4221	oxidoreductase activity
DP111_RS04585	COG1401	restriction endodeoxyribonuclease activity
DP111_RS04590	COG4268	DNA restriction-modification system
DP111_RS04600	COG2188	Transcriptional regulator
DP111_RS04605	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DP111_RS04610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DP111_RS04625	COG1660	Displays ATPase and GTPase activities
DP111_RS04630	COG4974	Belongs to the 'phage' integrase family
DP111_RS04645	COG0745	RESPONSE REGULATOR receiver
DP111_RS04665	COG1136	(ABC) transporter
DP111_RS04700	COG2382	esterase
DP111_RS04715	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DP111_RS04725	COG0222	ribosome binding
DP111_RS04730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DP111_RS04735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DP111_RS04740	COG0758	DNA mediated transformation
DP111_RS04745	COG0110	maltose O-acetyltransferase activity
DP111_RS04750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DP111_RS04750	COG0425	Belongs to the sulfur carrier protein TusA family
DP111_RS04760	COG1272	protein, Hemolysin III
DP111_RS04770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DP111_RS04775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DP111_RS04780	COG0582	viral genome integration into host DNA
DP111_RS04790	COG1396	sequence-specific DNA binding
DP111_RS04800	COG1940	carbohydrate kinase activity
DP111_RS04820	COG1175	transmembrane transport
DP111_RS04840	COG4806	L-rhamnose isomerase
DP111_RS04840	COG1070	Carbohydrate kinase
DP111_RS04900	COG2190	(PTS) system
DP111_RS04900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP111_RS04900	COG1263	PTS System
DP111_RS05050	COG0424	maF-like protein
DP111_RS05055	COG0737	Belongs to the 5'-nucleotidase family
DP111_RS05065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DP111_RS05070	COG0463	Glycosyl transferase, family 2
DP111_RS05080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DP111_RS05085	COG0284	orotidine-5'-phosphate decarboxylase activity
DP111_RS05090	COG0167	dihydroorotate dehydrogenase activity
DP111_RS05115	COG0297	glycogen (starch) synthase activity
DP111_RS05130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP111_RS05145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP111_RS05175	COG1396	sequence-specific DNA binding
DP111_RS05180	COG2197	response regulator
DP111_RS05195	COG1136	(ABC) transporter
DP111_RS05210	COG3843	relaxase mobilization nuclease domain protein
DP111_RS05450	COG0270	DNA (cytosine-5-)-methyltransferase activity
DP111_RS05480	COG3583	domain protein
DP111_RS05495	COG1126	abc transporter atp-binding protein
DP111_RS05505	COG0488	(ABC) transporter
DP111_RS05595	COG3716	PTS system mannose fructose sorbose family IID component
DP111_RS05605	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP111_RS05625	COG1070	Carbohydrate kinase
DP111_RS05665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP111_RS05665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP111_RS05675	COG3711	transcriptional antiterminator
DP111_RS05680	COG3684	Belongs to the aldolase LacD family
DP111_RS05685	COG1105	Belongs to the carbohydrate kinase PfkB family
DP111_RS05690	COG0698	ribose 5-phosphate isomerase
DP111_RS05695	COG0698	ribose 5-phosphate isomerase
DP111_RS05705	COG1349	DNA-binding transcription factor activity
DP111_RS05740	COG1194	a g-specific adenine glycosylase
DP111_RS05750	COG1132	(ABC) transporter
DP111_RS05755	COG1132	(ABC) transporter
DP111_RS05760	COG0280	phosphate acetyltransferase
DP111_RS05765	COG0564	pseudouridine synthase activity
DP111_RS05770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DP111_RS05775	COG2357	RelA SpoT domain protein
DP111_RS05780	COG4116	CYTH
DP111_RS05790	COG1104	cysteine desulfurase activity
DP111_RS05805	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DP111_RS05810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP111_RS05820	COG3764	Sortase (surface protein transpeptidase)
DP111_RS05825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DP111_RS05830	COG0039	L-malate dehydrogenase activity
DP111_RS05840	COG1079	Belongs to the binding-protein-dependent transport system permease family
DP111_RS05845	COG4603	Belongs to the binding-protein-dependent transport system permease family
DP111_RS05850	COG3845	ABC transporter
DP111_RS05855	COG1744	ABC transporter substrate-binding protein PnrA-like
DP111_RS05870	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DP111_RS05875	COG2813	Specifically methylates the guanine in position
DP111_RS05880	COG1072	(Pantothenic acid kinase))
DP111_RS05900	COG5002	protein histidine kinase activity
DP111_RS05905	COG0745	RESPONSE REGULATOR receiver
DP111_RS05915	COG0704	Plays a role in the regulation of phosphate uptake
DP111_RS05920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DP111_RS05925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DP111_RS05930	COG0581	inorganic phosphate transmembrane transporter activity
DP111_RS05935	COG0573	inorganic phosphate transmembrane transporter activity
DP111_RS05945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP111_RS05945	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DP111_RS05950	COG0483	inositol monophosphate 1-phosphatase activity
DP111_RS05955	COG4476	Belongs to the UPF0223 family
DP111_RS05960	COG1393	Belongs to the ArsC family
DP111_RS05965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DP111_RS05970	COG0196	riboflavin kinase activity
DP111_RS05975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DP111_RS06015	COG0561	phosphatase activity
DP111_RS06020	COG2195	Cleaves the N-terminal amino acid of tripeptides
DP111_RS06035	COG1695	Transcriptional regulator
DP111_RS06060	COG1846	Transcriptional regulator
DP111_RS06075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DP111_RS06080	COG2610	gluconate transmembrane transporter activity
DP111_RS06100	COG0302	gtp cyclohydrolase
DP111_RS06105	COG1051	belongs to the nudix hydrolase family
DP111_RS06160	COG1028	Short-chain dehydrogenase reductase Sdr
DP111_RS06165	COG1312	Catalyzes the dehydration of D-mannonate
DP111_RS06175	COG0800	Aldolase
DP111_RS06185	COG3250	beta-galactosidase activity
DP111_RS06195	COG2211	Major facilitator Superfamily
DP111_RS06220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DP111_RS06225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DP111_RS06230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DP111_RS06235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DP111_RS06240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DP111_RS06245	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DP111_RS06250	COG0356	it plays a direct role in the translocation of protons across the membrane
DP111_RS06260	COG1597	lipid kinase activity
DP111_RS06270	COG0701	Predicted permease
DP111_RS06275	COG3689	TIGRFAM TIGR03943 family protein
DP111_RS06280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DP111_RS06290	COG0552	protein localization to endoplasmic reticulum
DP111_RS06295	COG0561	phosphatase activity
DP111_RS06300	COG0561	phosphatase activity
DP111_RS06305	COG1196	nuclear chromosome segregation
DP111_RS06340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP111_RS06345	COG0538	isocitrate dehydrogenase activity
DP111_RS06350	COG0372	Belongs to the citrate synthase family
DP111_RS06355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DP111_RS06360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DP111_RS06365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DP111_RS06370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DP111_RS06405	COG1476	TRANSCRIPTIONal
DP111_RS06425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DP111_RS06435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DP111_RS06440	COG4122	O-methyltransferase activity
DP111_RS06465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP111_RS06465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP111_RS06480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DP111_RS06485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DP111_RS06495	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DP111_RS06505	COG1116	anion transmembrane transporter activity
DP111_RS06505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DP111_RS06510	COG4120	Belongs to the binding-protein-dependent transport system permease family
DP111_RS06525	COG3684	Belongs to the aldolase LacD family
DP111_RS06535	COG3679	Belongs to the UPF0342 family
DP111_RS06540	COG0287	Prephenate dehydrogenase
DP111_RS06545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DP111_RS06550	COG0710	3-dehydroquinate dehydratase activity
DP111_RS06555	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DP111_RS06560	COG1368	sulfuric ester hydrolase activity
DP111_RS06575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DP111_RS06585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DP111_RS06615	COG1216	Glycosyl transferase, family 2
DP111_RS06630	COG1442	glycosyl transferase family 8
DP111_RS06630	COG1216	Glycosyl transferase, family 2
DP111_RS06635	COG1442	glycosyl transferase family 8
DP111_RS06665	COG1216	Glycosyl transferase, family 2
DP111_RS06665	COG1442	glycosyl transferase family 8
DP111_RS06695	COG1091	dTDP-4-dehydrorhamnose reductase activity
DP111_RS06700	COG1088	dTDP-glucose 4,6-dehydratase activity
DP111_RS06715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DP111_RS06730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DP111_RS06735	COG2384	SAM-dependent methyltransferase
DP111_RS06750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DP111_RS06760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DP111_RS06760	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DP111_RS06765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DP111_RS06775	COG0300	oxidoreductase activity
DP111_RS06780	COG1234	tRNA 3'-trailer cleavage
DP111_RS06790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DP111_RS06795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DP111_RS06805	COG2807	transmembrane transport
DP111_RS06810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DP111_RS06815	COG1702	phosphate starvation-inducible protein PhoH
DP111_RS06820	COG4479	Belongs to the UPF0346 family
DP111_RS06835	COG2996	Protein conserved in bacteria
DP111_RS06840	COG0233	cytoplasmic translational termination
DP111_RS06845	COG0528	UMP kinase activity
DP111_RS06850	COG2244	polysaccharide biosynthetic process
DP111_RS06860	COG0625	glutathione transferase activity
DP111_RS06885	COG0346	lactoylglutathione lyase activity
DP111_RS06890	COG0697	spore germination
DP111_RS06890	COG1674	ftsk spoiiie
DP111_RS06895	COG1621	beta-fructofuranosidase activity
DP111_RS06900	COG1653	transport
DP111_RS06905	COG0395	ABC-type sugar transport system, permease component
DP111_RS06910	COG4209	transmembrane transport
DP111_RS06915	COG1609	Transcriptional regulator
DP111_RS06935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DP111_RS06945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DP111_RS06955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DP111_RS06965	COG1181	Belongs to the D-alanine--D-alanine ligase family
DP111_RS06970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DP111_RS06975	COG0768	penicillin binding
DP111_RS06980	COG0488	(ABC) transporter
DP111_RS06990	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DP111_RS07000	COG0745	RESPONSE REGULATOR receiver
DP111_RS07010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP111_RS07015	COG0765	amino acid transport
DP111_RS07020	COG0765	amino acid transport
DP111_RS07025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DP111_RS07040	COG0438	transferase activity, transferring glycosyl groups
DP111_RS07055	COG1609	Transcriptional regulator
DP111_RS07070	COG0343	queuine tRNA-ribosyltransferase activity
DP111_RS07090	COG1832	CoA-binding protein
DP111_RS07100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DP111_RS07100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DP111_RS07125	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DP111_RS07130	COG2217	Heavy metal translocating P-type atpase
DP111_RS07145	COG1063	alcohol dehydrogenase
DP111_RS07150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DP111_RS07155	COG0557	exoribonuclease II activity
DP111_RS07160	COG0017	Asparaginyl-tRNA synthetase
DP111_RS07170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DP111_RS07175	COG2814	Major facilitator Superfamily
DP111_RS07185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DP111_RS07190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DP111_RS07195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DP111_RS07205	COG1737	Transcriptional regulator
DP111_RS07215	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DP111_RS07225	COG1011	Hydrolase
DP111_RS07230	COG1132	(ABC) transporter
DP111_RS07235	COG1132	(ABC) transporter
DP111_RS07340	COG0740	serine-type endopeptidase activity
DP111_RS07420	COG0582	viral genome integration into host DNA
DP111_RS07485	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DP111_RS07565	COG4974	Belongs to the 'phage' integrase family
DP111_RS07590	COG2177	Part of the ABC transporter FtsEX involved in
DP111_RS07595	COG2884	Cell division ATP-binding protein ftsE
DP111_RS07605	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DP111_RS07640	COG1078	dGTPase activity
DP111_RS07650	COG0149	triose-phosphate isomerase activity
DP111_RS07660	COG3093	addiction module antidote protein HigA
DP111_RS07670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DP111_RS07685	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DP111_RS07690	COG0772	Belongs to the SEDS family
DP111_RS07710	COG3859	Proton-coupled thiamine transporter YuaJ
DP111_RS07720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DP111_RS07730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DP111_RS07740	COG0577	efflux transmembrane transporter activity
DP111_RS07745	COG1136	(ABC) transporter
DP111_RS07750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DP111_RS07755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP111_RS07760	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
DP111_RS07765	COG1268	BioY protein
DP111_RS07770	COG4443	Transcriptional Coactivator p15 (PC4)
DP111_RS07785	COG0826	peptidase U32
DP111_RS07800	COG0789	Transcriptional regulator
DP111_RS07840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DP111_RS07850	COG0765	amino acid transport
DP111_RS07855	COG4703	Protein of unknown function (DUF1797)
DP111_RS07860	COG0542	response to heat
DP111_RS07865	COG0494	nUDIX hydrolase
DP111_RS07865	COG0406	alpha-ribazole phosphatase activity
DP111_RS07885	COG3599	regulation of cell shape
DP111_RS07900	COG1799	cell septum assembly
DP111_RS07905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DP111_RS07910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DP111_RS07925	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DP111_RS07950	COG4886	Leucine-rich repeat (LRR) protein
DP111_RS07955	COG0681	Belongs to the peptidase S26 family
DP111_RS07980	COG1217	gtp-binding protein TYPA
DP111_RS08035	COG0525	valine-tRNA ligase activity
DP111_RS08045	COG0346	lactoylglutathione lyase activity
DP111_RS08060	COG2017	converts alpha-aldose to the beta-anomer
DP111_RS08070	COG3716	PTS system mannose fructose sorbose family IID component
DP111_RS08080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP111_RS08090	COG2188	Transcriptional regulator
DP111_RS08095	COG2188	Transcriptional regulator
DP111_RS08105	COG3557	Belongs to the UPF0374 family
DP111_RS08115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP111_RS08115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DP111_RS08115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DP111_RS08120	COG1105	Belongs to the carbohydrate kinase PfkB family
DP111_RS08125	COG1349	DNA-binding transcription factor activity
DP111_RS08130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DP111_RS08135	COG0336	Belongs to the RNA methyltransferase TrmD family
DP111_RS08140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DP111_RS08145	COG0534	Mate efflux family protein
DP111_RS08155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DP111_RS08160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DP111_RS08185	COG1177	transmembrane transport
DP111_RS08190	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP111_RS08195	COG3842	ATPase activity
DP111_RS08200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DP111_RS08205	COG0083	homoserine kinase activity
DP111_RS08210	COG0460	homoserine dehydrogenase
DP111_RS08215	COG0726	polysaccharide deacetylase
DP111_RS08220	COG1132	(ABC) transporter
DP111_RS08235	COG0228	four-way junction DNA binding
DP111_RS08245	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DP111_RS08250	COG2521	methyltransferase
DP111_RS08250	COG2136	Putative SAM-dependent methyltransferase
DP111_RS08260	COG0505	Belongs to the CarA family
DP111_RS08265	COG0540	Belongs to the ATCase OTCase family
DP111_RS08270	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DP111_RS08280	COG2824	Alkylphosphonate utilization operon protein PhnA
DP111_RS08285	COG0564	pseudouridine synthase activity
DP111_RS08305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DP111_RS08310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DP111_RS08320	COG1114	Component of the transport system for branched-chain amino acids
DP111_RS08325	COG0301	tRNA thio-modification
DP111_RS08330	COG1104	cysteine desulfurase activity
DP111_RS08355	COG0539	negative regulation of cytoplasmic translation
DP111_RS08375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DP111_RS08385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DP111_RS08400	COG2184	nucleotidyltransferase activity
DP111_RS08405	COG0187	DNA topoisomerase II activity
DP111_RS08415	COG1074	ATP-dependent DNA helicase activity
DP111_RS08420	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DP111_RS08450	COG1131	(ABC) transporter
DP111_RS08480	COG1011	Hydrolase
DP111_RS08485	COG1122	ATPase activity
DP111_RS08490	COG1122	ATPase activity
DP111_RS08505	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DP111_RS08525	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DP111_RS08540	COG0210	DNA helicase
DP111_RS08545	COG3177	Filamentation induced by cAMP protein fic
DP111_RS08560	COG1164	Oligoendopeptidase f
DP111_RS08570	COG0346	lactoylglutathione lyase activity
DP111_RS08575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP111_RS08580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DP111_RS08585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DP111_RS08595	COG0446	pyridine nucleotide-disulphide oxidoreductase
DP111_RS08600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP111_RS08605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DP111_RS08655	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DP111_RS08660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP111_RS08670	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DP111_RS08680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DP111_RS08685	COG4684	Psort location CytoplasmicMembrane, score
DP111_RS08690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DP111_RS08745	COG0531	amino acid
DP111_RS08755	COG0708	Exodeoxyribonuclease III
DP111_RS08770	COG1393	Belongs to the ArsC family
DP111_RS08775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DP111_RS08780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DP111_RS08790	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DP111_RS08800	COG4467	Involved in initiation control of chromosome replication
DP111_RS08805	COG0470	DNA polymerase III
DP111_RS08810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DP111_RS08815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP111_RS08830	COG0517	IMP dehydrogenase activity
DP111_RS08835	COG0658	competence protein
DP111_RS08835	COG2333	competence protein COMEC
DP111_RS08840	COG1555	photosystem II stabilization
DP111_RS08840	COG1596	polysaccharide export
DP111_RS08845	COG0204	Acyl-transferase
DP111_RS08850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DP111_RS08855	COG1120	ATPase activity
DP111_RS08860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DP111_RS08865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP111_RS08870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP111_RS08875	COG0386	Belongs to the glutathione peroxidase family
DP111_RS08880	COG1187	pseudouridine synthase activity
DP111_RS08885	COG0435	Glutathione S-transferase
DP111_RS08895	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DP111_RS08900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DP111_RS08905	COG1696	Membrane protein involved in D-alanine export
DP111_RS08945	COG0363	glucosamine-6-phosphate deaminase activity
DP111_RS08950	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DP111_RS08955	COG1438	arginine binding
DP111_RS08960	COG3064	Membrane
DP111_RS08960	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DP111_RS08960	COG3583	domain protein
DP111_RS08965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DP111_RS08970	COG1288	antiporter activity
DP111_RS08975	COG0549	Belongs to the carbamate kinase family
DP111_RS08980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP111_RS08985	COG0454	-acetyltransferase
DP111_RS09005	COG1481	regulation of sporulation
DP111_RS09010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DP111_RS09015	COG1660	Displays ATPase and GTPase activities
DP111_RS09020	COG0251	oxidation-reduction process
DP111_RS09025	COG0534	Mate efflux family protein
DP111_RS09035	COG0436	Aminotransferase
DP111_RS09050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DP111_RS09055	COG0562	UDP-galactopyranose mutase
DP111_RS09070	COG1396	sequence-specific DNA binding
DP111_RS09085	COG2723	6-phospho-beta-galactosidase activity
DP111_RS09095	COG1447	Phosphotransferase system cellobiose-specific component IIA
DP111_RS09105	COG1105	Belongs to the carbohydrate kinase PfkB family
DP111_RS09110	COG0698	ribose 5-phosphate isomerase
DP111_RS09115	COG0698	ribose 5-phosphate isomerase
DP111_RS09120	COG1940	carbohydrate kinase activity
DP111_RS09135	COG3843	relaxase mobilization nuclease domain protein
DP111_RS09245	COG2274	protein secretion by the type I secretion system
DP111_RS09260	COG0463	Glycosyl transferase, family 2
DP111_RS09340	COG0270	DNA (cytosine-5-)-methyltransferase activity
DP111_RS09360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DP111_RS09370	COG0077	Prephenate dehydratase
DP111_RS09375	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DP111_RS09390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DP111_RS09415	COG4372	Transposase
DP111_RS09435	COG0463	Glycosyl transferase, family 2
DP111_RS09435	COG1216	Glycosyl transferase, family 2
DP111_RS09460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DP111_RS09465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DP111_RS09475	COG4464	protein tyrosine phosphatase activity
DP111_RS09485	COG3944	biosynthesis protein
DP111_RS09490	COG1316	TRANSCRIPTIONal
DP111_RS09495	COG3022	response to hydroperoxide
DP111_RS09500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP111_RS09515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DP111_RS09520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DP111_RS09525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DP111_RS09550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP111_RS09555	COG1126	abc transporter atp-binding protein
DP111_RS09560	COG0765	amino acid transport
DP111_RS09570	COG2137	regulation of response to DNA damage stimulus
DP111_RS09575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DP111_RS09660	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DP111_RS09665	COG1739	Uncharacterized protein family UPF0029
DP111_RS09675	COG1098	S1 RNA binding domain
DP111_RS09700	COG2815	serine threonine protein kinase
DP111_RS09700	COG0515	serine threonine protein kinase
DP111_RS09705	COG0631	protein serine/threonine phosphatase activity
DP111_RS09710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP111_RS09710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP111_RS09715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DP111_RS09720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DP111_RS09730	COG1758	RNA polymerase activity
DP111_RS09740	COG1418	mRNA catabolic process
DP111_RS09745	COG1854	S-ribosylhomocysteine lyase activity
DP111_RS09755	COG0116	Belongs to the methyltransferase superfamily
DP111_RS09765	COG3599	regulation of cell shape
DP111_RS09770	COG4474	Belongs to the UPF0398 family
DP111_RS09775	COG3331	DNA recombination
DP111_RS09780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP111_RS09785	COG0357	Ribosomal RNA small subunit methyltransferase G
DP111_RS09800	COG1122	ATPase activity
DP111_RS09810	COG1054	Belongs to the UPF0176 family
DP111_RS09820	COG4720	Psort location CytoplasmicMembrane, score
DP111_RS09830	COG0217	transcriptional regulatory protein
DP111_RS09845	COG1263	PTS System
DP111_RS09845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP111_RS09845	COG2190	(PTS) system
DP111_RS09860	COG0058	SHG alpha-glucan phosphorylase activity
DP111_RS09865	COG1640	4-alpha-glucanotransferase
DP111_RS09875	COG0242	peptide deformylase activity
DP111_RS09885	COG2348	transferase activity, transferring amino-acyl groups
DP111_RS09890	COG0789	Transcriptional regulator
DP111_RS09920	COG2226	methyltransferase
DP111_RS09925	COG0799	negative regulation of ribosome biogenesis
DP111_RS09930	COG1335	isochorismatase
DP111_RS09945	COG1713	HD superfamily hydrolase involved in NAD metabolism
DP111_RS09950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DP111_RS09955	COG1534	Rna-binding protein
DP111_RS09965	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DP111_RS09980	COG3142	Participates in the control of copper homeostasis
DP111_RS09995	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DP111_RS10000	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DP111_RS10005	COG1609	Transcriptional regulator
DP111_RS10015	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DP111_RS10020	COG0154	amidase activity
DP111_RS10025	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DP111_RS10045	COG1187	pseudouridine synthase activity
DP111_RS10065	COG0242	peptide deformylase activity
DP111_RS10075	COG0066	3-isopropylmalate dehydratase activity
DP111_RS10100	COG2309	aminopeptidase activity
DP111_RS10110	COG2176	DNA-directed DNA polymerase activity
DP111_RS10115	COG2376	Dihydroxyacetone kinase
DP111_RS10125	COG2376	Dihydroxyacetone kinase
DP111_RS10130	COG1461	Dihydroxyacetone kinase
DP111_RS10135	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DP111_RS10140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP111_RS10145	COG0442	prolyl-tRNA aminoacylation
DP111_RS10155	COG4589	Belongs to the CDS family
DP111_RS10160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DP111_RS10165	COG1862	Preprotein translocase
DP111_RS10175	COG1181	Belongs to the D-alanine--D-alanine ligase family
DP111_RS10175	COG2918	glutathione biosynthetic process
DP111_RS10185	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DP111_RS10190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DP111_RS10195	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DP111_RS10200	COG0542	response to heat
DP111_RS10205	COG4463	regulation of RNA biosynthetic process
DP111_RS10215	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DP111_RS10245	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DP111_RS10250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP111_RS10255	COG0492	ferredoxin-NADP+ reductase activity
DP111_RS10260	COG0564	pseudouridine synthase activity
DP111_RS10265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DP111_RS10285	COG1564	THIamine pyrophosphokinase
DP111_RS10295	COG1162	GTPase activity
DP111_RS10305	COG1132	(ABC) transporter
DP111_RS10330	COG4115	mRNA cleavage
DP111_RS10355	COG0084	hydrolase, TatD family'
DP111_RS10365	COG1847	R3H domain protein
DP111_RS10375	COG0594	ribonuclease P activity
DP111_RS10380	COG0165	Argininosuccinate lyase
DP111_RS10385	COG0137	argininosuccinate synthase activity
DP111_RS10395	COG1827	regulation of RNA biosynthetic process
DP111_RS10410	COG2040	homocysteine
DP111_RS10415	COG0833	amino acid
DP111_RS10460	COG0756	dUTP diphosphatase activity
DP111_RS10465	COG1132	(ABC) transporter
DP111_RS10470	COG1132	(ABC) transporter
DP111_RS10480	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DP111_RS10485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DP111_RS10490	COG0705	Rhomboid family
DP111_RS10495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DP111_RS10500	COG1473	amidohydrolase
DP111_RS10505	COG2171	N-acyltransferase activity
DP111_RS10510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DP111_RS10540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DP111_RS10565	COG3623	hexulose-6-phosphate isomerase
DP111_RS10590	COG1523	belongs to the glycosyl hydrolase 13 family
DP111_RS10595	COG1609	Transcriptional regulator
DP111_RS10600	COG1126	abc transporter atp-binding protein
DP111_RS10605	COG0765	amino acid transport
DP111_RS10610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP111_RS10620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP111_RS10630	COG1447	Phosphotransferase system cellobiose-specific component IIA
DP111_RS10640	COG3711	transcriptional antiterminator
DP111_RS10640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP111_RS10650	COG2723	6-phospho-beta-galactosidase activity
DP111_RS10665	COG3590	peptidase
DP111_RS10670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP111_RS10675	COG1321	iron dependent repressor
DP111_RS10675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP111_RS10680	COG1121	(ABC) transporter
DP111_RS10695	COG0803	Belongs to the bacterial solute-binding protein 9 family
DP111_RS10715	COG1490	D-aminoacyl-tRNA deacylase activity
DP111_RS10725	COG0737	Belongs to the 5'-nucleotidase family
DP111_RS10750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DP111_RS10770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DP111_RS10800	COG0737	Belongs to the 5'-nucleotidase family
DP111_RS10810	COG1328	CTP reductase activity
DP111_RS10815	COG1126	abc transporter atp-binding protein
DP111_RS10825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP111_RS10830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DP111_RS10850	COG1438	arginine binding
DP111_RS10885	COG2182	Extracellular solute-binding protein
DP111_RS10890	COG1175	transmembrane transport
DP111_RS10895	COG3833	ABC-type maltose transport systems, permease component
DP111_RS10900	COG5521	maltodextrose utilization protein MalA
DP111_RS10905	COG1609	Transcriptional regulator
DP111_RS10910	COG1523	belongs to the glycosyl hydrolase 13 family
DP111_RS10915	COG1780	Probably involved in ribonucleotide reductase function
DP111_RS10920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP111_RS10925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DP111_RS10930	COG2153	protein acetylation
DP111_RS10935	COG4989	oxidoreductase activity
DP111_RS10985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DP111_RS10995	COG0305	Participates in initiation and elongation during chromosome replication
DP111_RS11000	COG0359	binds to the 23S rRNA
DP111_RS11010	COG0445	tRNA wobble uridine modification
DP111_RS11020	COG1733	regulation of RNA biosynthetic process
DP111_RS11030	COG0482	sulfurtransferase activity
DP111_RS11035	COG1760	l-serine dehydratase
DP111_RS11040	COG1760	l-serine dehydratase
DP111_RS11050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DP111_RS11055	COG1122	ATPase activity
DP111_RS11060	COG1122	ATPase activity
DP111_RS11065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DP111_RS11070	COG1426	Protein conserved in bacteria
DP111_RS11075	COG0612	Peptidase, M16
DP111_RS11080	COG0612	Peptidase, M16
DP111_RS11090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DP111_RS11095	COG0516	GMP reductase activity
DP111_RS11095	COG0517	IMP dehydrogenase activity
DP111_RS11105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP111_RS11110	COG0488	(ABC) transporter
DP111_RS11140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DP111_RS11145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP111_RS11150	COG1475	DNA binding