locus-tag	class	description
SSU12_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SSU12_RS00010	COG0592	DNA-directed DNA polymerase activity
SSU12_RS00030	COG0012	GTP binding
SSU12_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
SSU12_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SSU12_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SSU12_RS00065	COG0037	tRNA processing
SSU12_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SSU12_RS00185	COG1792	Involved in formation and maintenance of cell shape
SSU12_RS00200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SSU12_RS00205	COG0436	Aminotransferase
SSU12_RS00210	COG1381	Involved in DNA repair and RecF pathway recombination
SSU12_RS00215	COG0416	fatty acid biosynthetic process
SSU12_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SSU12_RS00230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SSU12_RS00245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SSU12_RS00250	COG0138	bifunctional purine biosynthesis protein purh
SSU12_RS00255	COG0151	Belongs to the GarS family
SSU12_RS00260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SSU12_RS00280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SSU12_RS00300	COG1131	(ABC) transporter
SSU12_RS00310	COG1132	(ABC) transporter
SSU12_RS00315	COG2255	four-way junction helicase activity
SSU12_RS00325	COG0546	phosphoglycolate phosphatase activity
SSU12_RS00350	COG0285	dihydrofolate synthase activity
SSU12_RS00365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SSU12_RS00370	COG0632	four-way junction helicase activity
SSU12_RS00380	COG0519	Catalyzes the synthesis of GMP from XMP
SSU12_RS00395	COG1393	Belongs to the ArsC family
SSU12_RS00400	COG4472	Bacterial protein of unknown function (DUF965)
SSU12_RS00405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SSU12_RS00410	COG3906	Belongs to the UPF0473 family
SSU12_RS00430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SSU12_RS00435	COG0088	Forms part of the polypeptide exit tunnel
SSU12_RS00440	COG0089	rRNA binding
SSU12_RS00445	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SSU12_RS00450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SSU12_RS00455	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SSU12_RS00460	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SSU12_RS00465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SSU12_RS00470	COG0255	Belongs to the universal ribosomal protein uL29 family
SSU12_RS00475	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SSU12_RS00480	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SSU12_RS00485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SSU12_RS00490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SSU12_RS00495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SSU12_RS00505	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SSU12_RS00515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SSU12_RS00520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SSU12_RS00525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SSU12_RS00530	COG1841	ribosomal large subunit assembly
SSU12_RS00540	COG0201	protein transport
SSU12_RS00545	COG0563	adenylate kinase activity
SSU12_RS00550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SSU12_RS00555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SSU12_RS00560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SSU12_RS00570	COG0202	RNA polymerase activity
SSU12_RS00660	COG0582	viral genome integration into host DNA
SSU12_RS00670	COG2946	Replication initiation factor
SSU12_RS00715	COG1121	(ABC) transporter
SSU12_RS00720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SSU12_RS00725	COG3443	Belongs to the bacterial solute-binding protein 9 family
SSU12_RS00725	COG0803	Belongs to the bacterial solute-binding protein 9 family
SSU12_RS00755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SSU12_RS00760	COG0085	RNA polymerase activity
SSU12_RS00765	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SSU12_RS00780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SSU12_RS00785	COG1459	type II secretion system
SSU12_RS00790	COG4537	Required for transformation and DNA binding
SSU12_RS00820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SSU12_RS00830	COG0285	dihydrofolate synthase activity
SSU12_RS00835	COG1363	Peptidase, m42
SSU12_RS00845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SSU12_RS00855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SSU12_RS00880	COG0459	protein refolding
SSU12_RS00890	COG0049	tRNA binding
SSU12_RS00895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SSU12_RS00900	COG3590	peptidase
SSU12_RS00910	COG0126	phosphoglycerate kinase activity
SSU12_RS00920	COG0789	Transcriptional regulator
SSU12_RS00925	COG0174	glutamine synthetase
SSU12_RS00940	COG1214	PFAM Peptidase M22, glycoprotease
SSU12_RS00950	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SSU12_RS00955	COG2207	Transcriptional regulator
SSU12_RS00965	COG1175	transmembrane transport
SSU12_RS00970	COG0395	ABC-type sugar transport system, permease component
SSU12_RS00990	COG2855	membrane
SSU12_RS01015	COG1131	(ABC) transporter
SSU12_RS01020	COG2081	HI0933 family
SSU12_RS01025	COG2723	6-phospho-beta-galactosidase activity
SSU12_RS01035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SSU12_RS01050	COG3959	Transketolase, thiamine diphosphate binding domain
SSU12_RS01055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SSU12_RS01060	COG0584	glycerophosphoryl diester phosphodiesterase
SSU12_RS01065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SSU12_RS01070	COG2222	sugar isomerase
SSU12_RS01090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SSU12_RS01095	COG1882	Formate acetyltransferase
SSU12_RS01110	COG2910	NAD(P)H-binding
SSU12_RS01135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SSU12_RS01170	COG0363	glucosamine-6-phosphate deaminase activity
SSU12_RS01180	COG2217	Heavy metal translocating P-type atpase
SSU12_RS01185	COG2217	Heavy metal translocating P-type atpase
SSU12_RS01190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SSU12_RS01195	COG0681	Belongs to the peptidase S26 family
SSU12_RS01215	COG0366	Alpha amylase catalytic
SSU12_RS01220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SSU12_RS01220	COG1263	PTS System
SSU12_RS01225	COG2188	Transcriptional regulator
SSU12_RS01240	COG1193	negative regulation of DNA recombination
SSU12_RS01250	COG3118	belongs to the thioredoxin family
SSU12_RS01255	COG0318	PFAM AMP-dependent synthetase and ligase
SSU12_RS01260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SSU12_RS01260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SSU12_RS01285	COG1115	amino acid carrier protein
SSU12_RS01290	COG0668	transmembrane transport
SSU12_RS01305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SSU12_RS01310	COG0167	dihydroorotate dehydrogenase activity
SSU12_RS01315	COG2843	Capsule synthesis protein
SSU12_RS01320	COG0561	phosphatase activity
SSU12_RS01335	COG1131	(ABC) transporter
SSU12_RS01340	COG1309	transcriptional regulator
SSU12_RS01345	COG1511	domain protein
SSU12_RS01370	COG1346	cytolysis
SSU12_RS01380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SSU12_RS01385	COG0433	COG0433 Predicted ATPase
SSU12_RS01390	COG0494	nUDIX hydrolase
SSU12_RS01420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SSU12_RS01425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SSU12_RS01430	COG0124	histidyl-tRNA synthetase
SSU12_RS01435	COG1064	alcohol dehydrogenase
SSU12_RS01440	COG1012	belongs to the aldehyde dehydrogenase family
SSU12_RS01440	COG1454	alcohol dehydrogenase
SSU12_RS01450	COG4988	ABC transporter
SSU12_RS01455	COG1132	(ABC) transporter
SSU12_RS01470	COG1129	ABC transporter
SSU12_RS01475	COG0534	Mate efflux family protein
SSU12_RS01480	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SSU12_RS01495	COG1304	FMN binding
SSU12_RS01500	COG1132	(ABC) transporter
SSU12_RS01505	COG1132	(ABC) transporter
SSU12_RS01510	COG3830	Belongs to the UPF0237 family
SSU12_RS01515	COG2848	UPF0210 protein
SSU12_RS01520	COG0588	phosphoglycerate mutase activity
SSU12_RS01525	COG1420	regulation of RNA biosynthetic process
SSU12_RS01530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SSU12_RS01535	COG0443	Heat shock 70 kDa protein
SSU12_RS01540	COG0484	heat shock protein binding
SSU12_RS01545	COG0095	Lipoate-protein ligase
SSU12_RS01555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SSU12_RS01560	COG0765	amino acid transport
SSU12_RS01565	COG3655	Transcriptional regulator
SSU12_RS01575	COG2217	Heavy metal translocating P-type atpase
SSU12_RS01600	COG4475	Protein of unknown function (DUF436)
SSU12_RS01635	COG4221	oxidoreductase activity
SSU12_RS01640	COG1902	pentaerythritol trinitrate reductase activity
SSU12_RS01640	COG0446	pyridine nucleotide-disulphide oxidoreductase
SSU12_RS01645	COG1959	2 iron, 2 sulfur cluster binding
SSU12_RS01665	COG0544	peptidyl-prolyl cis-trans isomerase activity
SSU12_RS01685	COG3343	RNA polymerase activity
SSU12_RS01690	COG0504	CTP synthase activity
SSU12_RS01700	COG0191	fructose-bisphosphate aldolase activity
SSU12_RS01705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SSU12_RS01740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SSU12_RS01745	COG0252	asparaginase activity
SSU12_RS01760	COG0589	response to stress
SSU12_RS01765	COG0436	Aminotransferase
SSU12_RS01770	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SSU12_RS01775	COG1335	isochorismatase
SSU12_RS01780	COG0335	large ribosomal subunit rRNA binding
SSU12_RS01790	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SSU12_RS01795	COG0154	amidase activity
SSU12_RS01800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SSU12_RS01805	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SSU12_RS01810	COG1609	Transcriptional regulator
SSU12_RS01815	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SSU12_RS01820	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SSU12_RS01830	COG3142	Participates in the control of copper homeostasis
SSU12_RS01845	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SSU12_RS01850	COG1534	Rna-binding protein
SSU12_RS01855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SSU12_RS01860	COG1713	HD superfamily hydrolase involved in NAD metabolism
SSU12_RS01870	COG1335	isochorismatase
SSU12_RS01875	COG0799	negative regulation of ribosome biogenesis
SSU12_RS01880	COG2226	methyltransferase
SSU12_RS01885	COG5290	Psort location Cytoplasmic, score
SSU12_RS01895	COG0789	Transcriptional regulator
SSU12_RS01900	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SSU12_RS01920	COG0242	peptide deformylase activity
SSU12_RS01930	COG1640	4-alpha-glucanotransferase
SSU12_RS01935	COG0058	SHG alpha-glucan phosphorylase activity
SSU12_RS01950	COG2190	(PTS) system
SSU12_RS01950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SSU12_RS01950	COG1263	PTS System
SSU12_RS01965	COG0217	transcriptional regulatory protein
SSU12_RS01975	COG4720	Psort location CytoplasmicMembrane, score
SSU12_RS01985	COG1054	Belongs to the UPF0176 family
SSU12_RS01995	COG1122	ATPase activity
SSU12_RS02010	COG0357	Ribosomal RNA small subunit methyltransferase G
SSU12_RS02015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SSU12_RS02020	COG3331	DNA recombination
SSU12_RS02025	COG4474	Belongs to the UPF0398 family
SSU12_RS02030	COG3599	regulation of cell shape
SSU12_RS02035	COG0116	Belongs to the methyltransferase superfamily
SSU12_RS02045	COG1854	S-ribosylhomocysteine lyase activity
SSU12_RS02050	COG1418	mRNA catabolic process
SSU12_RS02060	COG1758	RNA polymerase activity
SSU12_RS02065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SSU12_RS02070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SSU12_RS02075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SSU12_RS02075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SSU12_RS02080	COG0631	protein serine/threonine phosphatase activity
SSU12_RS02085	COG0515	serine threonine protein kinase
SSU12_RS02085	COG2815	serine threonine protein kinase
SSU12_RS02110	COG1098	S1 RNA binding domain
SSU12_RS02120	COG1739	Uncharacterized protein family UPF0029
SSU12_RS02125	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SSU12_RS02205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SSU12_RS02210	COG2137	regulation of response to DNA damage stimulus
SSU12_RS02215	COG3557	Belongs to the UPF0374 family
SSU12_RS02225	COG2188	Transcriptional regulator
SSU12_RS02230	COG2188	Transcriptional regulator
SSU12_RS02240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SSU12_RS02250	COG3716	PTS system mannose fructose sorbose family IID component
SSU12_RS02260	COG2017	converts alpha-aldose to the beta-anomer
SSU12_RS02275	COG0346	lactoylglutathione lyase activity
SSU12_RS02325	COG1217	gtp-binding protein TYPA
SSU12_RS02340	COG0681	Belongs to the peptidase S26 family
SSU12_RS02370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SSU12_RS02385	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SSU12_RS02390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SSU12_RS02395	COG1799	cell septum assembly
SSU12_RS02410	COG3599	regulation of cell shape
SSU12_RS02430	COG0494	nUDIX hydrolase
SSU12_RS02430	COG0406	alpha-ribazole phosphatase activity
SSU12_RS02435	COG0542	response to heat
SSU12_RS02440	COG4703	Protein of unknown function (DUF1797)
SSU12_RS02445	COG0765	amino acid transport
SSU12_RS02455	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SSU12_RS02485	COG0789	Transcriptional regulator
SSU12_RS02500	COG0826	peptidase U32
SSU12_RS02515	COG4443	Transcriptional Coactivator p15 (PC4)
SSU12_RS02520	COG1268	BioY protein
SSU12_RS02525	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SSU12_RS02530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSU12_RS02535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SSU12_RS02540	COG1136	(ABC) transporter
SSU12_RS02545	COG0577	efflux transmembrane transporter activity
SSU12_RS02560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SSU12_RS02570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SSU12_RS02580	COG3859	Proton-coupled thiamine transporter YuaJ
SSU12_RS02600	COG0772	Belongs to the SEDS family
SSU12_RS02605	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SSU12_RS02610	COG1595	DNA-templated transcription, initiation
SSU12_RS02620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SSU12_RS02625	COG0149	triose-phosphate isomerase activity
SSU12_RS02635	COG1078	dGTPase activity
SSU12_RS02650	COG2826	transposase and inactivated derivatives, IS30 family
SSU12_RS02655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SSU12_RS02665	COG1131	(ABC) transporter
SSU12_RS02670	COG2188	Transcriptional regulator
SSU12_RS02680	COG0205	6-phosphofructokinase activity
SSU12_RS02685	COG0469	pyruvate kinase activity
SSU12_RS02695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SSU12_RS02700	COG0657	acetylesterase activity
SSU12_RS02700	COG2755	lipolytic protein G-D-S-L family
SSU12_RS02710	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SSU12_RS02715	COG0765	amino acid transport
SSU12_RS02720	COG1126	abc transporter atp-binding protein
SSU12_RS02725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SSU12_RS02740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SSU12_RS02745	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SSU12_RS02750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SSU12_RS02765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SSU12_RS02770	COG3022	response to hydroperoxide
SSU12_RS02780	COG3944	biosynthesis protein
SSU12_RS02790	COG4464	protein tyrosine phosphatase activity
SSU12_RS02805	COG0438	transferase activity, transferring glycosyl groups
SSU12_RS02820	COG1442	glycosyl transferase family 8
SSU12_RS02820	COG1216	Glycosyl transferase, family 2
SSU12_RS02825	COG1442	glycosyl transferase family 8
SSU12_RS02825	COG1216	Glycosyl transferase, family 2
SSU12_RS02850	COG2089	acid synthase
SSU12_RS02865	COG1083	cytidylyl-transferase
SSU12_RS02865	COG2755	lipolytic protein G-D-S-L family
SSU12_RS02950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SSU12_RS02955	COG0077	Prephenate dehydratase
SSU12_RS02965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SSU12_RS02970	COG0562	UDP-galactopyranose mutase
SSU12_RS02975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SSU12_RS03000	COG0436	Aminotransferase
SSU12_RS03020	COG0534	Mate efflux family protein
SSU12_RS03025	COG0251	oxidation-reduction process
SSU12_RS03030	COG1660	Displays ATPase and GTPase activities
SSU12_RS03035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SSU12_RS03040	COG1481	regulation of sporulation
SSU12_RS03055	COG0454	-acetyltransferase
SSU12_RS03060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SSU12_RS03065	COG0549	Belongs to the carbamate kinase family
SSU12_RS03070	COG1288	antiporter activity
SSU12_RS03075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SSU12_RS03080	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SSU12_RS03080	COG3583	domain protein
SSU12_RS03080	COG3064	Membrane
SSU12_RS03085	COG1438	arginine binding
SSU12_RS03090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SSU12_RS03095	COG0363	glucosamine-6-phosphate deaminase activity
SSU12_RS03125	COG1696	Membrane protein involved in D-alanine export
SSU12_RS03130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SSU12_RS03135	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SSU12_RS03145	COG0435	Glutathione S-transferase
SSU12_RS03150	COG1187	pseudouridine synthase activity
SSU12_RS03155	COG0386	Belongs to the glutathione peroxidase family
SSU12_RS03160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSU12_RS03165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SSU12_RS03170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SSU12_RS03175	COG1120	ATPase activity
SSU12_RS03180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SSU12_RS03185	COG0204	Acyl-transferase
SSU12_RS03190	COG1555	photosystem II stabilization
SSU12_RS03190	COG1596	polysaccharide export
SSU12_RS03195	COG0658	competence protein
SSU12_RS03195	COG2333	competence protein COMEC
SSU12_RS03205	COG0517	IMP dehydrogenase activity
SSU12_RS03220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SSU12_RS03225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SSU12_RS03230	COG0470	DNA polymerase III
SSU12_RS03235	COG4467	Involved in initiation control of chromosome replication
SSU12_RS03245	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SSU12_RS03255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SSU12_RS03260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SSU12_RS03265	COG1393	Belongs to the ArsC family
SSU12_RS03275	COG0708	Exodeoxyribonuclease III
SSU12_RS03285	COG0531	amino acid
SSU12_RS03330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SSU12_RS03335	COG4684	Psort location CytoplasmicMembrane, score
SSU12_RS03340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SSU12_RS03350	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SSU12_RS03360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSU12_RS03365	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SSU12_RS03375	COG0732	type I restriction modification DNA specificity domain
SSU12_RS03410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SSU12_RS03415	COG1349	DNA-binding transcription factor activity
SSU12_RS03425	COG1447	Phosphotransferase system cellobiose-specific component IIA
SSU12_RS03430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SSU12_RS03435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SSU12_RS03440	COG1882	Formate acetyltransferase
SSU12_RS03460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SSU12_RS03465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SSU12_RS03470	COG0446	pyridine nucleotide-disulphide oxidoreductase
SSU12_RS03480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SSU12_RS03485	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SSU12_RS03490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SSU12_RS03495	COG0346	lactoylglutathione lyase activity
SSU12_RS03505	COG1164	Oligoendopeptidase f
SSU12_RS03520	COG0210	DNA helicase
SSU12_RS03535	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SSU12_RS03550	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
SSU12_RS03565	COG1122	ATPase activity
SSU12_RS03570	COG1122	ATPase activity
SSU12_RS03575	COG1011	Hydrolase
SSU12_RS03605	COG1131	(ABC) transporter
SSU12_RS03635	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SSU12_RS03640	COG1074	ATP-dependent DNA helicase activity
SSU12_RS03650	COG0187	DNA topoisomerase II activity
SSU12_RS03675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SSU12_RS03685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SSU12_RS03710	COG0539	negative regulation of cytoplasmic translation
SSU12_RS03735	COG1104	cysteine desulfurase activity
SSU12_RS03740	COG0301	tRNA thio-modification
SSU12_RS03745	COG1114	Component of the transport system for branched-chain amino acids
SSU12_RS03750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SSU12_RS03755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SSU12_RS03775	COG0564	pseudouridine synthase activity
SSU12_RS03780	COG2824	Alkylphosphonate utilization operon protein PhnA
SSU12_RS03790	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SSU12_RS03795	COG0540	Belongs to the ATCase OTCase family
SSU12_RS03800	COG0505	Belongs to the CarA family
SSU12_RS03810	COG2521	methyltransferase
SSU12_RS03810	COG2136	Putative SAM-dependent methyltransferase
SSU12_RS03815	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SSU12_RS03825	COG0228	four-way junction DNA binding
SSU12_RS03840	COG1132	(ABC) transporter
SSU12_RS03845	COG0726	polysaccharide deacetylase
SSU12_RS03850	COG0460	homoserine dehydrogenase
SSU12_RS03855	COG0083	homoserine kinase activity
SSU12_RS03860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SSU12_RS03865	COG3842	ATPase activity
SSU12_RS03870	COG1176	ABC-type spermidine putrescine transport system, permease component I
SSU12_RS03875	COG1177	transmembrane transport
SSU12_RS03885	COG0038	chloride channel
SSU12_RS03900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SSU12_RS03905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SSU12_RS03920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SSU12_RS03925	COG0336	Belongs to the RNA methyltransferase TrmD family
SSU12_RS03930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SSU12_RS03935	COG1349	DNA-binding transcription factor activity
SSU12_RS03940	COG1105	Belongs to the carbohydrate kinase PfkB family
SSU12_RS03945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SSU12_RS03945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SSU12_RS03945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SSU12_RS03955	COG1307	EDD domain protein, DegV family
SSU12_RS03960	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SSU12_RS03965	COG0617	tRNA 3'-terminal CCA addition
SSU12_RS03970	COG0488	(ABC) transporter
SSU12_RS03980	COG1940	carbohydrate kinase activity
SSU12_RS03995	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SSU12_RS04000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SSU12_RS04010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SSU12_RS04030	COG0481	GTPase activity
SSU12_RS04055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SSU12_RS04060	COG2890	protein-(glutamine-N5) methyltransferase activity
SSU12_RS04065	COG0009	L-threonylcarbamoyladenylate synthase
SSU12_RS04075	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SSU12_RS04085	COG0741	lytic transglycosylase activity
SSU12_RS04090	COG4221	oxidoreductase activity
SSU12_RS04115	COG1401	restriction endodeoxyribonuclease activity
SSU12_RS04120	COG4268	DNA restriction-modification system
SSU12_RS04190	COG2188	Transcriptional regulator
SSU12_RS04195	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SSU12_RS04200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SSU12_RS04215	COG1660	Displays ATPase and GTPase activities
SSU12_RS04225	COG4974	Belongs to the 'phage' integrase family
SSU12_RS04240	COG0745	RESPONSE REGULATOR receiver
SSU12_RS04260	COG1136	(ABC) transporter
SSU12_RS04300	COG2382	esterase
SSU12_RS04310	COG3708	Transcriptional regulator
SSU12_RS04310	COG2207	Transcriptional regulator
SSU12_RS04315	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SSU12_RS04320	COG0647	UMP catabolic process
SSU12_RS04325	COG4974	Belongs to the 'phage' integrase family
SSU12_RS04335	COG1396	sequence-specific DNA binding
SSU12_RS04365	COG0463	Glycosyl transferase, family 2
SSU12_RS04370	COG3848	Pyruvate phosphate dikinase
SSU12_RS04370	COG0574	Belongs to the PEP-utilizing enzyme family
SSU12_RS04390	COG1131	(ABC) transporter
SSU12_RS04400	COG3843	relaxase mobilization nuclease domain protein
SSU12_RS04415	COG0613	PHP domain protein
SSU12_RS04420	COG0542	response to heat
SSU12_RS04425	COG1396	sequence-specific DNA binding
SSU12_RS04475	COG1192	Involved in chromosome partitioning
SSU12_RS04500	COG4443	Transcriptional Coactivator p15 (PC4)
SSU12_RS04505	COG1475	DNA binding
SSU12_RS04620	COG0270	DNA (cytosine-5-)-methyltransferase activity
SSU12_RS04635	COG0222	ribosome binding
SSU12_RS04640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SSU12_RS04645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SSU12_RS04650	COG0758	DNA mediated transformation
SSU12_RS04655	COG0110	maltose O-acetyltransferase activity
SSU12_RS04660	COG1937	Protein conserved in bacteria
SSU12_RS04670	COG0446	pyridine nucleotide-disulphide oxidoreductase
SSU12_RS04680	COG1272	protein, Hemolysin III
SSU12_RS04690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SSU12_RS04695	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SSU12_RS04710	COG0737	Belongs to the 5'-nucleotidase family
SSU12_RS04720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SSU12_RS04725	COG0463	Glycosyl transferase, family 2
SSU12_RS04735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SSU12_RS04740	COG0284	orotidine-5'-phosphate decarboxylase activity
SSU12_RS04745	COG0167	dihydroorotate dehydrogenase activity
SSU12_RS04770	COG0297	glycogen (starch) synthase activity
SSU12_RS04780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SSU12_RS04785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SSU12_RS04800	COG3583	domain protein
SSU12_RS04825	COG1126	abc transporter atp-binding protein
SSU12_RS04835	COG0488	(ABC) transporter
SSU12_RS04840	COG2873	o-acetylhomoserine
SSU12_RS04865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SSU12_RS04865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SSU12_RS04875	COG3711	transcriptional antiterminator
SSU12_RS04880	COG3684	Belongs to the aldolase LacD family
SSU12_RS04885	COG1105	Belongs to the carbohydrate kinase PfkB family
SSU12_RS04890	COG1105	Belongs to the carbohydrate kinase PfkB family
SSU12_RS04895	COG0698	ribose 5-phosphate isomerase
SSU12_RS04900	COG0698	ribose 5-phosphate isomerase
SSU12_RS04910	COG1349	DNA-binding transcription factor activity
SSU12_RS04940	COG1396	sequence-specific DNA binding
SSU12_RS04945	COG1194	a g-specific adenine glycosylase
SSU12_RS04955	COG1132	(ABC) transporter
SSU12_RS04960	COG1132	(ABC) transporter
SSU12_RS04965	COG0280	phosphate acetyltransferase
SSU12_RS04970	COG0564	pseudouridine synthase activity
SSU12_RS04975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SSU12_RS04980	COG2357	RelA SpoT domain protein
SSU12_RS04985	COG4116	CYTH
SSU12_RS04995	COG1104	cysteine desulfurase activity
SSU12_RS05010	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SSU12_RS05015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SSU12_RS05025	COG3764	Sortase (surface protein transpeptidase)
SSU12_RS05030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SSU12_RS05035	COG0039	L-malate dehydrogenase activity
SSU12_RS05040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SSU12_RS05045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SSU12_RS05050	COG1079	Belongs to the binding-protein-dependent transport system permease family
SSU12_RS05055	COG4603	Belongs to the binding-protein-dependent transport system permease family
SSU12_RS05060	COG3845	ABC transporter
SSU12_RS05065	COG1744	ABC transporter substrate-binding protein PnrA-like
SSU12_RS05080	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SSU12_RS05085	COG2813	Specifically methylates the guanine in position
SSU12_RS05090	COG1072	(Pantothenic acid kinase))
SSU12_RS05115	COG5002	protein histidine kinase activity
SSU12_RS05120	COG0745	RESPONSE REGULATOR receiver
SSU12_RS05135	COG0704	Plays a role in the regulation of phosphate uptake
SSU12_RS05140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SSU12_RS05145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SSU12_RS05150	COG0581	inorganic phosphate transmembrane transporter activity
SSU12_RS05155	COG0573	inorganic phosphate transmembrane transporter activity
SSU12_RS05165	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SSU12_RS05165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SSU12_RS05170	COG0483	inositol monophosphate 1-phosphatase activity
SSU12_RS05175	COG4476	Belongs to the UPF0223 family
SSU12_RS05180	COG1393	Belongs to the ArsC family
SSU12_RS05185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SSU12_RS05190	COG0196	riboflavin kinase activity
SSU12_RS05195	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SSU12_RS05255	COG0561	phosphatase activity
SSU12_RS05260	COG2195	Cleaves the N-terminal amino acid of tripeptides
SSU12_RS05295	COG3759	membrane
SSU12_RS05300	COG1846	Transcriptional regulator
SSU12_RS05315	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SSU12_RS05320	COG2610	gluconate transmembrane transporter activity
SSU12_RS05340	COG0302	gtp cyclohydrolase
SSU12_RS05345	COG1051	belongs to the nudix hydrolase family
SSU12_RS05370	COG0072	phenylalanine-tRNA ligase activity
SSU12_RS05370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SSU12_RS05400	COG1028	Short-chain dehydrogenase reductase Sdr
SSU12_RS05405	COG1312	Catalyzes the dehydration of D-mannonate
SSU12_RS05415	COG0800	Aldolase
SSU12_RS05425	COG3250	beta-galactosidase activity
SSU12_RS05435	COG2211	Major facilitator Superfamily
SSU12_RS05450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SSU12_RS05460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SSU12_RS05465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SSU12_RS05470	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SSU12_RS05475	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SSU12_RS05480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SSU12_RS05485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SSU12_RS05490	COG0356	it plays a direct role in the translocation of protons across the membrane
SSU12_RS05500	COG1597	lipid kinase activity
SSU12_RS05510	COG0701	Predicted permease
SSU12_RS05515	COG3689	TIGRFAM TIGR03943 family protein
SSU12_RS05520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SSU12_RS05535	COG0552	protein localization to endoplasmic reticulum
SSU12_RS05540	COG0561	phosphatase activity
SSU12_RS05545	COG0561	phosphatase activity
SSU12_RS05550	COG1196	nuclear chromosome segregation
SSU12_RS05575	COG2826	transposase and inactivated derivatives, IS30 family
SSU12_RS05590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SSU12_RS05595	COG0538	isocitrate dehydrogenase activity
SSU12_RS05600	COG0372	Belongs to the citrate synthase family
SSU12_RS05605	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SSU12_RS05610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SSU12_RS05615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SSU12_RS05625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SSU12_RS05630	COG1609	Transcriptional regulator
SSU12_RS05645	COG5492	domain, Protein
SSU12_RS05650	COG5492	domain, Protein
SSU12_RS05655	COG5492	domain, Protein
SSU12_RS05665	COG3716	PTS system mannose fructose sorbose family IID component
SSU12_RS05675	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SSU12_RS05680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SSU12_RS05705	COG1028	Short-chain dehydrogenase reductase Sdr
SSU12_RS05740	COG1476	TRANSCRIPTIONal
SSU12_RS05765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SSU12_RS05775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SSU12_RS05780	COG4122	O-methyltransferase activity
SSU12_RS05805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SSU12_RS05805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SSU12_RS05815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SSU12_RS05820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SSU12_RS05825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SSU12_RS05830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SSU12_RS05835	COG1116	anion transmembrane transporter activity
SSU12_RS05835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SSU12_RS05840	COG4120	Belongs to the binding-protein-dependent transport system permease family
SSU12_RS05860	COG3684	Belongs to the aldolase LacD family
SSU12_RS05870	COG3679	Belongs to the UPF0342 family
SSU12_RS05875	COG0287	Prephenate dehydrogenase
SSU12_RS05880	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SSU12_RS05885	COG0710	3-dehydroquinate dehydratase activity
SSU12_RS05890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SSU12_RS05895	COG1368	sulfuric ester hydrolase activity
SSU12_RS05910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SSU12_RS05920	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SSU12_RS05950	COG1216	Glycosyl transferase, family 2
SSU12_RS05965	COG1442	glycosyl transferase family 8
SSU12_RS05965	COG1216	Glycosyl transferase, family 2
SSU12_RS05970	COG1442	glycosyl transferase family 8
SSU12_RS06000	COG0463	Glycosyl transferase, family 2
SSU12_RS06030	COG1091	dTDP-4-dehydrorhamnose reductase activity
SSU12_RS06035	COG1088	dTDP-glucose 4,6-dehydratase activity
SSU12_RS06050	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SSU12_RS06060	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SSU12_RS06065	COG2384	SAM-dependent methyltransferase
SSU12_RS06080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SSU12_RS06095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SSU12_RS06095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SSU12_RS06100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SSU12_RS06110	COG0300	oxidoreductase activity
SSU12_RS06115	COG1234	tRNA 3'-trailer cleavage
SSU12_RS06125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SSU12_RS06130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SSU12_RS06140	COG2807	transmembrane transport
SSU12_RS06145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SSU12_RS06150	COG1702	phosphate starvation-inducible protein PhoH
SSU12_RS06155	COG4479	Belongs to the UPF0346 family
SSU12_RS06170	COG2996	Protein conserved in bacteria
SSU12_RS06175	COG0233	cytoplasmic translational termination
SSU12_RS06180	COG0528	UMP kinase activity
SSU12_RS06185	COG2244	polysaccharide biosynthetic process
SSU12_RS06190	COG0625	glutathione transferase activity
SSU12_RS06215	COG0346	lactoylglutathione lyase activity
SSU12_RS06220	COG1674	ftsk spoiiie
SSU12_RS06220	COG0697	spore germination
SSU12_RS06225	COG1621	beta-fructofuranosidase activity
SSU12_RS06235	COG0395	ABC-type sugar transport system, permease component
SSU12_RS06240	COG4209	transmembrane transport
SSU12_RS06245	COG1609	Transcriptional regulator
SSU12_RS06265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SSU12_RS06280	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SSU12_RS06290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SSU12_RS06300	COG1181	Belongs to the D-alanine--D-alanine ligase family
SSU12_RS06305	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SSU12_RS06310	COG0768	penicillin binding
SSU12_RS06320	COG0488	(ABC) transporter
SSU12_RS06325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SSU12_RS06335	COG0745	RESPONSE REGULATOR receiver
SSU12_RS06340	COG1126	abc transporter atp-binding protein
SSU12_RS06345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SSU12_RS06350	COG0765	amino acid transport
SSU12_RS06355	COG0765	amino acid transport
SSU12_RS06360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SSU12_RS06375	COG0438	transferase activity, transferring glycosyl groups
SSU12_RS06390	COG1609	Transcriptional regulator
SSU12_RS06400	COG0343	queuine tRNA-ribosyltransferase activity
SSU12_RS06410	COG1832	CoA-binding protein
SSU12_RS06420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SSU12_RS06420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SSU12_RS06435	COG1136	(ABC) transporter
SSU12_RS06445	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SSU12_RS06450	COG2217	Heavy metal translocating P-type atpase
SSU12_RS06465	COG1063	alcohol dehydrogenase
SSU12_RS06470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SSU12_RS06475	COG0557	exoribonuclease II activity
SSU12_RS06485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SSU12_RS06490	COG2814	Major facilitator Superfamily
SSU12_RS06500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SSU12_RS06505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SSU12_RS06510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SSU12_RS06520	COG1737	Transcriptional regulator
SSU12_RS06530	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SSU12_RS06540	COG1011	Hydrolase
SSU12_RS06545	COG1132	(ABC) transporter
SSU12_RS06550	COG1132	(ABC) transporter
SSU12_RS06575	COG2177	Part of the ABC transporter FtsEX involved in
SSU12_RS06580	COG2884	Cell division ATP-binding protein ftsE
SSU12_RS06585	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SSU12_RS06590	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SSU12_RS06615	COG2826	transposase and inactivated derivatives, IS30 family
SSU12_RS06645	COG2151	metal-sulfur cluster biosynthetic enzyme
SSU12_RS06650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SSU12_RS06655	COG0358	DNA primase activity
SSU12_RS06660	COG1970	mechanosensitive ion channel activity
SSU12_RS06665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SSU12_RS06670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SSU12_RS06680	COG0647	UMP catabolic process
SSU12_RS06685	COG1051	belongs to the nudix hydrolase family
SSU12_RS06695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SSU12_RS06705	COG0058	SHG alpha-glucan phosphorylase activity
SSU12_RS06710	COG0813	purine-nucleoside phosphorylase activity
SSU12_RS06715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SSU12_RS06725	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SSU12_RS06730	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SSU12_RS06740	COG0732	type I restriction modification DNA specificity domain
SSU12_RS06755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SSU12_RS06770	COG2268	Band 7 protein
SSU12_RS06775	COG1704	LemA family
SSU12_RS06785	COG1573	uracil-dna glycosylase
SSU12_RS06820	COG2226	methyltransferase
SSU12_RS06825	COG0488	(ABC) transporter
SSU12_RS06830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SSU12_RS06845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SSU12_RS06850	COG3442	glutamine amidotransferase
SSU12_RS06855	COG2226	methyltransferase
SSU12_RS06870	COG0488	(ABC) transporter
SSU12_RS06905	COG3842	ATPase activity
SSU12_RS06925	COG1263	PTS System
SSU12_RS06925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SSU12_RS06925	COG2190	(PTS) system
SSU12_RS06930	COG3711	transcriptional antiterminator
SSU12_RS06935	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SSU12_RS06940	COG3527	Alpha-acetolactate decarboxylase
SSU12_RS06950	COG0628	permease
SSU12_RS06955	COG2706	6-phosphogluconolactonase activity
SSU12_RS06965	COG1011	Hydrolase
SSU12_RS07005	COG0560	Phosphoserine phosphatase
SSU12_RS07010	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SSU12_RS07015	COG0187	DNA topoisomerase II activity
SSU12_RS07020	COG0693	protein deglycase activity
SSU12_RS07025	COG0772	Belongs to the SEDS family
SSU12_RS07030	COG0582	viral genome integration into host DNA
SSU12_RS07115	COG0582	viral genome integration into host DNA
SSU12_RS07130	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SSU12_RS07135	COG0716	FMN binding
SSU12_RS07145	COG1605	Chorismate mutase
SSU12_RS07145	COG0287	Prephenate dehydrogenase
SSU12_RS07150	COG0038	chloride channel
SSU12_RS07385	COG3561	AntA/AntB antirepressor
SSU12_RS07425	COG0737	Belongs to the 5'-nucleotidase family
SSU12_RS07430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SSU12_RS07435	COG1466	dna polymerase III delta subunit
SSU12_RS07470	COG0683	leucine binding
SSU12_RS07485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SSU12_RS07490	COG0366	Alpha amylase catalytic
SSU12_RS07500	COG0395	ABC-type sugar transport system, permease component
SSU12_RS07505	COG1175	transmembrane transport
SSU12_RS07510	COG1653	transport
SSU12_RS07520	COG2207	Transcriptional regulator
SSU12_RS07525	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SSU12_RS07530	COG0626	cystathionine gamma-synthase activity
SSU12_RS07550	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SSU12_RS07555	COG2827	Endonuclease containing a URI domain
SSU12_RS07580	COG0640	Transcriptional regulator
SSU12_RS07585	COG0513	Belongs to the DEAD box helicase family
SSU12_RS07590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SSU12_RS07630	COG0494	nUDIX hydrolase
SSU12_RS07635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SSU12_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
SSU12_RS07680	COG0577	efflux transmembrane transporter activity
SSU12_RS07685	COG1136	(ABC) transporter
SSU12_RS07690	COG2205	protein histidine kinase activity
SSU12_RS07705	COG0436	Aminotransferase
SSU12_RS07715	COG1174	glycine betaine transport
SSU12_RS07720	COG1125	glycine betaine transport
SSU12_RS07720	COG0517	IMP dehydrogenase activity
SSU12_RS07740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SSU12_RS07745	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SSU12_RS07750	COG1482	cell wall glycoprotein biosynthetic process
SSU12_RS07775	COG3091	SprT-like family
SSU12_RS07785	COG0656	L-ascorbic acid biosynthetic process
SSU12_RS07790	COG4708	membrane
SSU12_RS07795	COG2246	polysaccharide biosynthetic process
SSU12_RS07805	COG0024	Methionine aminopeptidase
SSU12_RS07815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SSU12_RS07820	COG2249	NAD(P)H dehydrogenase (quinone) activity
SSU12_RS07825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SSU12_RS07830	COG2131	deaminase
SSU12_RS07840	COG1363	Peptidase, m42
SSU12_RS07855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SSU12_RS07860	COG1956	GAF domain-containing protein
SSU12_RS07870	COG1695	Transcriptional regulator
SSU12_RS07885	COG0513	Belongs to the DEAD box helicase family
SSU12_RS07890	COG0726	polysaccharide deacetylase
SSU12_RS07910	COG0183	Belongs to the thiolase family
SSU12_RS07915	COG3425	synthase
SSU12_RS07940	COG0776	regulation of translation
SSU12_RS07950	COG2755	lipolytic protein G-D-S-L family
SSU12_RS07955	COG1307	EDD domain protein, DegV family
SSU12_RS07960	COG0497	DNA recombination
SSU12_RS07965	COG1438	arginine binding
SSU12_RS07970	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SSU12_RS07980	COG1722	exodeoxyribonuclease VII activity
SSU12_RS07985	COG1570	exodeoxyribonuclease VII activity
SSU12_RS07990	COG2321	neutral zinc metallopeptidase
SSU12_RS07995	COG1755	Isoprenylcysteine carboxyl methyltransferase
SSU12_RS08000	COG5002	protein histidine kinase activity
SSU12_RS08005	COG0745	RESPONSE REGULATOR receiver
SSU12_RS08030	COG1227	inorganic diphosphatase activity
SSU12_RS08040	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SSU12_RS08045	COG1253	flavin adenine dinucleotide binding
SSU12_RS08050	COG1119	ATPase activity
SSU12_RS08055	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SSU12_RS08065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SSU12_RS08070	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SSU12_RS08085	COG4470	Protein conserved in bacteria
SSU12_RS08090	COG3480	Lon protease (S16) C-terminal proteolytic domain
SSU12_RS08095	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SSU12_RS08100	COG0742	ribosomal rna small subunit methyltransferase
SSU12_RS08110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SSU12_RS08115	COG4483	Protein conserved in bacteria
SSU12_RS08120	COG2197	response regulator
SSU12_RS08125	COG2203	Gaf domain
SSU12_RS08125	COG4585	Histidine kinase
SSU12_RS08130	COG0842	Transport permease protein
SSU12_RS08135	COG1131	(ABC) transporter
SSU12_RS08150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SSU12_RS08165	COG0671	phosphoesterase, PA-phosphatase related
SSU12_RS08170	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SSU12_RS08185	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SSU12_RS08190	COG1187	pseudouridine synthase activity
SSU12_RS08195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SSU12_RS08200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SSU12_RS08205	COG0582	viral genome integration into host DNA
SSU12_RS08225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SSU12_RS08230	COG3763	UPF0154 protein
SSU12_RS08240	COG3579	cysteine-type endopeptidase activity
SSU12_RS08255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SSU12_RS08260	COG1254	Belongs to the acylphosphatase family
SSU12_RS08270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SSU12_RS08275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SSU12_RS08285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SSU12_RS08295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SSU12_RS08310	COG1160	GTP binding
SSU12_RS08320	COG1484	DNA-dependent DNA replication
SSU12_RS08330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SSU12_RS08335	COG0628	permease
SSU12_RS08340	COG0745	RESPONSE REGULATOR receiver
SSU12_RS08345	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SSU12_RS08355	COG0492	ferredoxin-NADP+ reductase activity
SSU12_RS08365	COG0513	Belongs to the DEAD box helicase family
SSU12_RS08375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SSU12_RS08380	COG0768	penicillin binding
SSU12_RS08390	COG0275	rRNA processing
SSU12_RS08440	COG4939	FMN-binding domain protein
SSU12_RS08445	COG0142	geranyltranstransferase activity
SSU12_RS08450	COG1252	NADH dehydrogenase
SSU12_RS08465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SSU12_RS08470	COG0569	domain protein
SSU12_RS08475	COG0534	Mate efflux family protein
SSU12_RS08485	COG4224	UPF0291 protein
SSU12_RS08490	COG0751	glycine-tRNA ligase activity
SSU12_RS08515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SSU12_RS08520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SSU12_RS08525	COG1464	Belongs to the NlpA lipoprotein family
SSU12_RS08530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SSU12_RS08535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SSU12_RS08540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SSU12_RS08545	COG2252	PERMEase
SSU12_RS08550	COG0561	phosphatase activity
SSU12_RS08560	COG3715	PTS system
SSU12_RS08565	COG3716	PTS system mannose fructose sorbose family IID component
SSU12_RS08590	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SSU12_RS08635	COG0439	Biotin carboxylase
SSU12_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
SSU12_RS08660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SSU12_RS08665	COG2070	2-Nitropropane dioxygenase
SSU12_RS08675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SSU12_RS08685	COG1024	Enoyl-CoA hydratase
SSU12_RS08690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SSU12_RS08695	COG0527	aspartate kinase activity
SSU12_RS08705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SSU12_RS08710	COG0736	holo-[acyl-carrier-protein] synthase activity
SSU12_RS08715	COG0653	protein targeting
SSU12_RS08725	COG1940	carbohydrate kinase activity
SSU12_RS08730	COG2190	(PTS) system
SSU12_RS08730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SSU12_RS08730	COG1263	PTS System
SSU12_RS08735	COG1621	beta-fructofuranosidase activity
SSU12_RS08740	COG1609	Transcriptional regulator
SSU12_RS08745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SSU12_RS08760	COG0006	proline dipeptidase activity
SSU12_RS08765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SSU12_RS08785	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SSU12_RS08790	COG0629	single-stranded DNA binding
SSU12_RS08800	COG2826	transposase and inactivated derivatives, IS30 family
SSU12_RS08805	COG0095	Lipoate-protein ligase
SSU12_RS08820	COG0508	dehydrogenase complex catalyzes the overall conversion of
SSU12_RS08825	COG0508	dehydrogenase complex catalyzes the overall conversion of
SSU12_RS08825	COG0022	dehydrogenase e1 component
SSU12_RS08830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SSU12_RS08835	COG2860	membrane
SSU12_RS08850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SSU12_RS08855	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SSU12_RS08865	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SSU12_RS08870	COG0195	Participates in both transcription termination and antitermination
SSU12_RS08880	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SSU12_RS08890	COG4473	ABC transporter
SSU12_RS08895	COG1131	(ABC) transporter
SSU12_RS08900	COG0537	adenosine 5'-monophosphoramidase activity
SSU12_RS08910	COG1316	TRANSCRIPTIONal
SSU12_RS08920	COG0802	atpase or kinase
SSU12_RS08925	COG1461	Dihydroxyacetone kinase
SSU12_RS08940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SSU12_RS08945	COG0601	transmembrane transport
SSU12_RS08950	COG4608	Belongs to the ABC transporter superfamily
SSU12_RS08965	COG1686	Belongs to the peptidase S11 family
SSU12_RS08980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SSU12_RS08985	COG0719	Fe-S assembly protein
SSU12_RS08995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SSU12_RS09000	COG4862	establishment of competence for transformation
SSU12_RS09005	COG1968	undecaprenyl-diphosphatase activity
SSU12_RS09010	COG0765	amino acid transport
SSU12_RS09030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SSU12_RS09035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SSU12_RS09040	COG0440	acetolactate synthase activity
SSU12_RS09045	COG0028	Belongs to the TPP enzyme family
SSU12_RS09065	COG0129	dihydroxy-acid dehydratase activity
SSU12_RS09075	COG2151	metal-sulfur cluster biosynthetic enzyme
SSU12_RS09095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SSU12_RS09110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SSU12_RS09135	COG3842	ATPase activity
SSU12_RS09145	COG2207	Transcriptional regulator
SSU12_RS09145	COG4753	response regulator
SSU12_RS09150	COG2972	Histidine kinase
SSU12_RS09165	COG1653	transport
SSU12_RS09170	COG0395	ABC-type sugar transport system, permease component
SSU12_RS09175	COG1175	transmembrane transport
SSU12_RS09210	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SSU12_RS09230	COG1045	serine acetyltransferase
SSU12_RS09235	COG1185	polyribonucleotide nucleotidyltransferase activity
SSU12_RS09255	COG1263	PTS System
SSU12_RS09255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SSU12_RS09265	COG1737	Transcriptional regulator
SSU12_RS09270	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SSU12_RS09290	COG1187	pseudouridine synthase activity
SSU12_RS09310	COG0242	peptide deformylase activity
SSU12_RS09320	COG0066	3-isopropylmalate dehydratase activity
SSU12_RS09345	COG2309	aminopeptidase activity
SSU12_RS09360	COG2176	DNA-directed DNA polymerase activity
SSU12_RS09365	COG2376	Dihydroxyacetone kinase
SSU12_RS09375	COG2376	Dihydroxyacetone kinase
SSU12_RS09380	COG1461	Dihydroxyacetone kinase
SSU12_RS09385	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SSU12_RS09390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SSU12_RS09395	COG0442	prolyl-tRNA aminoacylation
SSU12_RS09405	COG4589	Belongs to the CDS family
SSU12_RS09410	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SSU12_RS09415	COG1862	Preprotein translocase
SSU12_RS09425	COG1181	Belongs to the D-alanine--D-alanine ligase family
SSU12_RS09425	COG2918	glutathione biosynthetic process
SSU12_RS09435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SSU12_RS09440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SSU12_RS09455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SSU12_RS09465	COG4463	regulation of RNA biosynthetic process
SSU12_RS09480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SSU12_RS09515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SSU12_RS09520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SSU12_RS09525	COG0492	ferredoxin-NADP+ reductase activity
SSU12_RS09530	COG0564	pseudouridine synthase activity
SSU12_RS09535	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SSU12_RS09555	COG1564	THIamine pyrophosphokinase
SSU12_RS09565	COG1162	GTPase activity
SSU12_RS09620	COG4115	mRNA cleavage
SSU12_RS09655	COG0084	hydrolase, TatD family'
SSU12_RS09665	COG1847	R3H domain protein
SSU12_RS09675	COG0594	ribonuclease P activity
SSU12_RS09680	COG0165	Argininosuccinate lyase
SSU12_RS09685	COG0137	argininosuccinate synthase activity
SSU12_RS09695	COG1827	regulation of RNA biosynthetic process
SSU12_RS09710	COG2040	homocysteine
SSU12_RS09715	COG0833	amino acid
SSU12_RS09760	COG0756	dUTP diphosphatase activity
SSU12_RS09765	COG1132	(ABC) transporter
SSU12_RS09770	COG1132	(ABC) transporter
SSU12_RS09780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SSU12_RS09785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SSU12_RS09790	COG0705	Rhomboid family
SSU12_RS09795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SSU12_RS09800	COG1473	amidohydrolase
SSU12_RS09805	COG2171	N-acyltransferase activity
SSU12_RS09820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SSU12_RS09840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SSU12_RS09865	COG3623	hexulose-6-phosphate isomerase
SSU12_RS09890	COG1523	belongs to the glycosyl hydrolase 13 family
SSU12_RS09895	COG1609	Transcriptional regulator
SSU12_RS09900	COG1126	abc transporter atp-binding protein
SSU12_RS09905	COG0765	amino acid transport
SSU12_RS09910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SSU12_RS09915	COG3942	CHAP domain
SSU12_RS09920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SSU12_RS09930	COG1447	Phosphotransferase system cellobiose-specific component IIA
SSU12_RS09940	COG3711	transcriptional antiterminator
SSU12_RS09940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SSU12_RS09950	COG2723	6-phospho-beta-galactosidase activity
SSU12_RS09955	COG1486	melibiose metabolic process
SSU12_RS09965	COG3590	peptidase
SSU12_RS09970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SSU12_RS09975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SSU12_RS09975	COG1321	iron dependent repressor
SSU12_RS09980	COG1121	(ABC) transporter
SSU12_RS09990	COG0803	Belongs to the bacterial solute-binding protein 9 family
SSU12_RS10025	COG1490	D-aminoacyl-tRNA deacylase activity
SSU12_RS10035	COG0737	Belongs to the 5'-nucleotidase family
SSU12_RS10050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SSU12_RS10070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SSU12_RS10095	COG0737	Belongs to the 5'-nucleotidase family
SSU12_RS10105	COG1328	CTP reductase activity
SSU12_RS10135	COG1438	arginine binding
SSU12_RS10140	COG0018	arginyl-trna synthetase
SSU12_RS10160	COG1640	4-alpha-glucanotransferase
SSU12_RS10165	COG2182	Extracellular solute-binding protein
SSU12_RS10170	COG1175	transmembrane transport
SSU12_RS10175	COG3833	ABC-type maltose transport systems, permease component
SSU12_RS10180	COG5521	maltodextrose utilization protein MalA
SSU12_RS10185	COG1609	Transcriptional regulator
SSU12_RS10190	COG1523	belongs to the glycosyl hydrolase 13 family
SSU12_RS10195	COG1780	Probably involved in ribonucleotide reductase function
SSU12_RS10200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SSU12_RS10205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SSU12_RS10210	COG2153	protein acetylation
SSU12_RS10215	COG4989	oxidoreductase activity
SSU12_RS10220	COG1216	Glycosyl transferase, family 2
SSU12_RS10225	COG1472	Belongs to the glycosyl hydrolase 3 family
SSU12_RS10265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SSU12_RS10280	COG0305	Participates in initiation and elongation during chromosome replication
SSU12_RS10285	COG0359	binds to the 23S rRNA
SSU12_RS10295	COG0445	tRNA wobble uridine modification
SSU12_RS10310	COG1051	belongs to the nudix hydrolase family
SSU12_RS10315	COG1733	regulation of RNA biosynthetic process
SSU12_RS10325	COG0482	sulfurtransferase activity
SSU12_RS10330	COG1760	l-serine dehydratase
SSU12_RS10335	COG1760	l-serine dehydratase
SSU12_RS10345	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SSU12_RS10350	COG1122	ATPase activity
SSU12_RS10355	COG1122	ATPase activity
SSU12_RS10360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SSU12_RS10365	COG1426	Protein conserved in bacteria
SSU12_RS10370	COG0612	Peptidase, M16
SSU12_RS10375	COG0612	Peptidase, M16
SSU12_RS10385	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SSU12_RS10390	COG0517	IMP dehydrogenase activity
SSU12_RS10390	COG0516	GMP reductase activity
SSU12_RS10400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SSU12_RS10405	COG0488	(ABC) transporter
SSU12_RS10435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SSU12_RS10440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SSU12_RS10445	COG1475	DNA binding
SSU12_RS10455	COG0582	viral genome integration into host DNA
