locus-tag	class	description
BVD85_RS00045	COG1792	Involved in formation and maintenance of cell shape
BVD85_RS00060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVD85_RS00065	COG0436	Aminotransferase
BVD85_RS00070	COG1381	Involved in DNA repair and RecF pathway recombination
BVD85_RS00075	COG0416	fatty acid biosynthetic process
BVD85_RS00080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVD85_RS00090	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BVD85_RS00105	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVD85_RS00110	COG0138	bifunctional purine biosynthesis protein purh
BVD85_RS00115	COG0151	Belongs to the GarS family
BVD85_RS00120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BVD85_RS00140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BVD85_RS00165	COG1131	(ABC) transporter
BVD85_RS00175	COG1132	(ABC) transporter
BVD85_RS00180	COG2255	four-way junction helicase activity
BVD85_RS00190	COG0546	phosphoglycolate phosphatase activity
BVD85_RS00215	COG0285	dihydrofolate synthase activity
BVD85_RS00230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BVD85_RS00235	COG0632	four-way junction helicase activity
BVD85_RS00245	COG0519	Catalyzes the synthesis of GMP from XMP
BVD85_RS00260	COG1393	Belongs to the ArsC family
BVD85_RS00265	COG4472	Bacterial protein of unknown function (DUF965)
BVD85_RS00270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BVD85_RS00275	COG3906	Belongs to the UPF0473 family
BVD85_RS00300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BVD85_RS00305	COG0088	Forms part of the polypeptide exit tunnel
BVD85_RS00310	COG0089	rRNA binding
BVD85_RS00315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BVD85_RS00320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BVD85_RS00325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BVD85_RS00330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BVD85_RS00335	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BVD85_RS00340	COG0255	Belongs to the universal ribosomal protein uL29 family
BVD85_RS00345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BVD85_RS00350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BVD85_RS00355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BVD85_RS00360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BVD85_RS00365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BVD85_RS00375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BVD85_RS00385	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BVD85_RS00390	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BVD85_RS00395	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BVD85_RS00400	COG1841	ribosomal large subunit assembly
BVD85_RS00410	COG0201	protein transport
BVD85_RS00415	COG0563	adenylate kinase activity
BVD85_RS00420	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BVD85_RS00425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BVD85_RS00430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BVD85_RS00440	COG0202	RNA polymerase activity
BVD85_RS00530	COG0582	viral genome integration into host DNA
BVD85_RS00540	COG2946	Replication initiation factor
BVD85_RS00575	COG0582	viral genome integration into host DNA
BVD85_RS00590	COG1121	(ABC) transporter
BVD85_RS00595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVD85_RS00600	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVD85_RS00600	COG3443	Belongs to the bacterial solute-binding protein 9 family
BVD85_RS00630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVD85_RS00635	COG0085	RNA polymerase activity
BVD85_RS00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BVD85_RS00655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVD85_RS00660	COG1459	type II secretion system
BVD85_RS00665	COG4537	Required for transformation and DNA binding
BVD85_RS00695	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BVD85_RS00705	COG0285	dihydrofolate synthase activity
BVD85_RS00710	COG1363	Peptidase, m42
BVD85_RS00720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVD85_RS00730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD85_RS00755	COG0459	protein refolding
BVD85_RS00765	COG0049	tRNA binding
BVD85_RS00770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVD85_RS00775	COG3590	peptidase
BVD85_RS00785	COG0126	phosphoglycerate kinase activity
BVD85_RS00795	COG0789	Transcriptional regulator
BVD85_RS00800	COG0174	glutamine synthetase
BVD85_RS00815	COG1214	PFAM Peptidase M22, glycoprotease
BVD85_RS00825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BVD85_RS00830	COG2207	Transcriptional regulator
BVD85_RS00840	COG1175	transmembrane transport
BVD85_RS00845	COG0395	ABC-type sugar transport system, permease component
BVD85_RS00865	COG2855	membrane
BVD85_RS00890	COG1131	(ABC) transporter
BVD85_RS00895	COG2081	HI0933 family
BVD85_RS00900	COG2723	6-phospho-beta-galactosidase activity
BVD85_RS00910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVD85_RS00925	COG3959	Transketolase, thiamine diphosphate binding domain
BVD85_RS00930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BVD85_RS00935	COG0584	glycerophosphoryl diester phosphodiesterase
BVD85_RS00940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BVD85_RS00945	COG2222	sugar isomerase
BVD85_RS00980	COG1882	Formate acetyltransferase
BVD85_RS00995	COG2910	NAD(P)H-binding
BVD85_RS01020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVD85_RS01055	COG0363	glucosamine-6-phosphate deaminase activity
BVD85_RS01065	COG2217	Heavy metal translocating P-type atpase
BVD85_RS01070	COG2217	Heavy metal translocating P-type atpase
BVD85_RS01075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVD85_RS01080	COG0681	Belongs to the peptidase S26 family
BVD85_RS01105	COG0366	Alpha amylase catalytic
BVD85_RS01110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVD85_RS01110	COG1263	PTS System
BVD85_RS01115	COG2188	Transcriptional regulator
BVD85_RS01130	COG1193	negative regulation of DNA recombination
BVD85_RS01140	COG3118	belongs to the thioredoxin family
BVD85_RS01145	COG0318	PFAM AMP-dependent synthetase and ligase
BVD85_RS01150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVD85_RS01150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVD85_RS01175	COG1115	amino acid carrier protein
BVD85_RS01180	COG0668	transmembrane transport
BVD85_RS01195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVD85_RS01200	COG0167	dihydroorotate dehydrogenase activity
BVD85_RS01205	COG2843	Capsule synthesis protein
BVD85_RS01210	COG0561	phosphatase activity
BVD85_RS01225	COG1131	(ABC) transporter
BVD85_RS01230	COG1309	transcriptional regulator
BVD85_RS01235	COG1511	domain protein
BVD85_RS01260	COG1346	cytolysis
BVD85_RS01265	COG2116	formate transmembrane transporter activity
BVD85_RS01270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BVD85_RS01275	COG0433	COG0433 Predicted ATPase
BVD85_RS01280	COG0494	nUDIX hydrolase
BVD85_RS01305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVD85_RS01310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BVD85_RS01315	COG0124	histidyl-tRNA synthetase
BVD85_RS01320	COG1064	alcohol dehydrogenase
BVD85_RS01325	COG1454	alcohol dehydrogenase
BVD85_RS01325	COG1012	belongs to the aldehyde dehydrogenase family
BVD85_RS01335	COG4988	ABC transporter
BVD85_RS01340	COG1132	(ABC) transporter
BVD85_RS01355	COG1129	ABC transporter
BVD85_RS01360	COG0534	Mate efflux family protein
BVD85_RS01365	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BVD85_RS01380	COG1304	FMN binding
BVD85_RS01385	COG1132	(ABC) transporter
BVD85_RS01390	COG1132	(ABC) transporter
BVD85_RS01395	COG3830	Belongs to the UPF0237 family
BVD85_RS01400	COG2848	UPF0210 protein
BVD85_RS01405	COG0588	phosphoglycerate mutase activity
BVD85_RS01410	COG1420	regulation of RNA biosynthetic process
BVD85_RS01415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BVD85_RS01420	COG0443	Heat shock 70 kDa protein
BVD85_RS01425	COG0484	heat shock protein binding
BVD85_RS01435	COG0095	Lipoate-protein ligase
BVD85_RS01445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD85_RS01450	COG0765	amino acid transport
BVD85_RS01455	COG3655	Transcriptional regulator
BVD85_RS01465	COG2217	Heavy metal translocating P-type atpase
BVD85_RS01490	COG4475	Protein of unknown function (DUF436)
BVD85_RS01520	COG4221	oxidoreductase activity
BVD85_RS01525	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVD85_RS01525	COG1902	pentaerythritol trinitrate reductase activity
BVD85_RS01530	COG1959	2 iron, 2 sulfur cluster binding
BVD85_RS01550	COG0544	peptidyl-prolyl cis-trans isomerase activity
BVD85_RS01570	COG3343	RNA polymerase activity
BVD85_RS01575	COG0504	CTP synthase activity
BVD85_RS01585	COG0191	fructose-bisphosphate aldolase activity
BVD85_RS01590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BVD85_RS01625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVD85_RS01630	COG0252	asparaginase activity
BVD85_RS01645	COG0589	response to stress
BVD85_RS01650	COG0436	Aminotransferase
BVD85_RS01660	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BVD85_RS01665	COG1335	isochorismatase
BVD85_RS01670	COG0335	large ribosomal subunit rRNA binding
BVD85_RS01680	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVD85_RS01685	COG0154	amidase activity
BVD85_RS01690	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVD85_RS01695	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BVD85_RS01700	COG1609	Transcriptional regulator
BVD85_RS01705	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BVD85_RS01710	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BVD85_RS01720	COG3142	Participates in the control of copper homeostasis
BVD85_RS01735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BVD85_RS01745	COG1534	Rna-binding protein
BVD85_RS01750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BVD85_RS01755	COG1713	HD superfamily hydrolase involved in NAD metabolism
BVD85_RS01780	COG0799	negative regulation of ribosome biogenesis
BVD85_RS01785	COG2226	methyltransferase
BVD85_RS01790	COG5290	Psort location Cytoplasmic, score
BVD85_RS01800	COG0789	Transcriptional regulator
BVD85_RS01805	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BVD85_RS01825	COG0242	peptide deformylase activity
BVD85_RS01835	COG1640	4-alpha-glucanotransferase
BVD85_RS01840	COG0058	SHG alpha-glucan phosphorylase activity
BVD85_RS01855	COG2190	(PTS) system
BVD85_RS01855	COG1263	PTS System
BVD85_RS01855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVD85_RS01870	COG0217	transcriptional regulatory protein
BVD85_RS01880	COG4720	Psort location CytoplasmicMembrane, score
BVD85_RS01890	COG1054	Belongs to the UPF0176 family
BVD85_RS01900	COG1122	ATPase activity
BVD85_RS01915	COG0357	Ribosomal RNA small subunit methyltransferase G
BVD85_RS01920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVD85_RS01925	COG3331	DNA recombination
BVD85_RS01930	COG4474	Belongs to the UPF0398 family
BVD85_RS01935	COG3599	regulation of cell shape
BVD85_RS01945	COG0116	Belongs to the methyltransferase superfamily
BVD85_RS01955	COG1854	S-ribosylhomocysteine lyase activity
BVD85_RS01960	COG1418	mRNA catabolic process
BVD85_RS01970	COG1758	RNA polymerase activity
BVD85_RS01975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVD85_RS01980	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVD85_RS01985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVD85_RS01985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVD85_RS01990	COG0631	protein serine/threonine phosphatase activity
BVD85_RS01995	COG0515	serine threonine protein kinase
BVD85_RS01995	COG2815	serine threonine protein kinase
BVD85_RS02020	COG1098	S1 RNA binding domain
BVD85_RS02030	COG1739	Uncharacterized protein family UPF0029
BVD85_RS02035	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BVD85_RS02070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVD85_RS02075	COG2137	regulation of response to DNA damage stimulus
BVD85_RS02080	COG3557	Belongs to the UPF0374 family
BVD85_RS02090	COG2188	Transcriptional regulator
BVD85_RS02095	COG2188	Transcriptional regulator
BVD85_RS02105	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVD85_RS02115	COG3716	PTS system mannose fructose sorbose family IID component
BVD85_RS02125	COG2017	converts alpha-aldose to the beta-anomer
BVD85_RS02140	COG0346	lactoylglutathione lyase activity
BVD85_RS02190	COG1217	gtp-binding protein TYPA
BVD85_RS02205	COG0681	Belongs to the peptidase S26 family
BVD85_RS02240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVD85_RS02255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BVD85_RS02260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BVD85_RS02265	COG1799	cell septum assembly
BVD85_RS02280	COG3599	regulation of cell shape
BVD85_RS02300	COG0406	alpha-ribazole phosphatase activity
BVD85_RS02300	COG0494	nUDIX hydrolase
BVD85_RS02305	COG0542	response to heat
BVD85_RS02310	COG4703	Protein of unknown function (DUF1797)
BVD85_RS02315	COG0765	amino acid transport
BVD85_RS02325	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BVD85_RS02365	COG0789	Transcriptional regulator
BVD85_RS02380	COG0826	peptidase U32
BVD85_RS02395	COG4443	Transcriptional Coactivator p15 (PC4)
BVD85_RS02400	COG1268	BioY protein
BVD85_RS02405	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BVD85_RS02410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVD85_RS02415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD85_RS02420	COG1136	(ABC) transporter
BVD85_RS02425	COG0577	efflux transmembrane transporter activity
BVD85_RS02440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BVD85_RS02450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVD85_RS02460	COG3859	Proton-coupled thiamine transporter YuaJ
BVD85_RS02480	COG0772	Belongs to the SEDS family
BVD85_RS02485	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BVD85_RS02490	COG1595	DNA-templated transcription, initiation
BVD85_RS02500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVD85_RS02505	COG0149	triose-phosphate isomerase activity
BVD85_RS02515	COG1078	dGTPase activity
BVD85_RS02530	COG2826	transposase and inactivated derivatives, IS30 family
BVD85_RS02535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BVD85_RS02545	COG1131	(ABC) transporter
BVD85_RS02550	COG2188	Transcriptional regulator
BVD85_RS02560	COG0205	6-phosphofructokinase activity
BVD85_RS02565	COG0469	pyruvate kinase activity
BVD85_RS02575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVD85_RS02580	COG0657	acetylesterase activity
BVD85_RS02580	COG2755	lipolytic protein G-D-S-L family
BVD85_RS02590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVD85_RS02595	COG0765	amino acid transport
BVD85_RS02600	COG1126	abc transporter atp-binding protein
BVD85_RS02605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD85_RS02625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BVD85_RS02630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BVD85_RS02635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVD85_RS02650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD85_RS02655	COG3022	response to hydroperoxide
BVD85_RS02665	COG3944	biosynthesis protein
BVD85_RS02675	COG4464	protein tyrosine phosphatase activity
BVD85_RS02690	COG0438	transferase activity, transferring glycosyl groups
BVD85_RS02705	COG1216	Glycosyl transferase, family 2
BVD85_RS02705	COG1442	glycosyl transferase family 8
BVD85_RS02710	COG1216	Glycosyl transferase, family 2
BVD85_RS02710	COG1442	glycosyl transferase family 8
BVD85_RS02745	COG2089	acid synthase
BVD85_RS02760	COG1083	cytidylyl-transferase
BVD85_RS02760	COG2755	lipolytic protein G-D-S-L family
BVD85_RS02835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BVD85_RS02840	COG0077	Prephenate dehydratase
BVD85_RS02850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVD85_RS02860	COG0562	UDP-galactopyranose mutase
BVD85_RS02865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVD85_RS02890	COG0436	Aminotransferase
BVD85_RS02900	COG0017	Asparaginyl-tRNA synthetase
BVD85_RS02920	COG0534	Mate efflux family protein
BVD85_RS02925	COG0251	oxidation-reduction process
BVD85_RS02930	COG1660	Displays ATPase and GTPase activities
BVD85_RS02935	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BVD85_RS02940	COG1481	regulation of sporulation
BVD85_RS02955	COG0454	-acetyltransferase
BVD85_RS02960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BVD85_RS02965	COG0549	Belongs to the carbamate kinase family
BVD85_RS02970	COG1288	antiporter activity
BVD85_RS02975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVD85_RS02980	COG3583	domain protein
BVD85_RS02980	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVD85_RS02980	COG3064	Membrane
BVD85_RS02985	COG1438	arginine binding
BVD85_RS02990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BVD85_RS02995	COG0363	glucosamine-6-phosphate deaminase activity
BVD85_RS03030	COG1696	Membrane protein involved in D-alanine export
BVD85_RS03035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVD85_RS03040	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BVD85_RS03050	COG0435	Glutathione S-transferase
BVD85_RS03055	COG1187	pseudouridine synthase activity
BVD85_RS03060	COG0386	Belongs to the glutathione peroxidase family
BVD85_RS03065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVD85_RS03070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVD85_RS03075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVD85_RS03080	COG1120	ATPase activity
BVD85_RS03085	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BVD85_RS03090	COG0204	Acyl-transferase
BVD85_RS03095	COG1555	photosystem II stabilization
BVD85_RS03095	COG1596	polysaccharide export
BVD85_RS03100	COG2333	competence protein COMEC
BVD85_RS03100	COG0658	competence protein
BVD85_RS03110	COG0517	IMP dehydrogenase activity
BVD85_RS03125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVD85_RS03130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BVD85_RS03135	COG0470	DNA polymerase III
BVD85_RS03140	COG4467	Involved in initiation control of chromosome replication
BVD85_RS03150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BVD85_RS03160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVD85_RS03165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVD85_RS03170	COG1393	Belongs to the ArsC family
BVD85_RS03180	COG0708	Exodeoxyribonuclease III
BVD85_RS03190	COG0531	amino acid
BVD85_RS03255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVD85_RS03260	COG4684	Psort location CytoplasmicMembrane, score
BVD85_RS03265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVD85_RS03275	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BVD85_RS03285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVD85_RS03290	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BVD85_RS03300	COG0732	type I restriction modification DNA specificity domain
BVD85_RS03335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BVD85_RS03340	COG1349	DNA-binding transcription factor activity
BVD85_RS03350	COG1447	Phosphotransferase system cellobiose-specific component IIA
BVD85_RS03355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVD85_RS03360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVD85_RS03365	COG1882	Formate acetyltransferase
BVD85_RS03385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVD85_RS03390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVD85_RS03395	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVD85_RS03405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BVD85_RS03410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BVD85_RS03415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BVD85_RS03420	COG0346	lactoylglutathione lyase activity
BVD85_RS03430	COG1164	Oligoendopeptidase f
BVD85_RS03445	COG0210	DNA helicase
BVD85_RS03460	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BVD85_RS03475	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BVD85_RS03490	COG1122	ATPase activity
BVD85_RS03495	COG1122	ATPase activity
BVD85_RS03500	COG1011	Hydrolase
BVD85_RS03530	COG1131	(ABC) transporter
BVD85_RS03560	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BVD85_RS03565	COG1074	ATP-dependent DNA helicase activity
BVD85_RS03575	COG0187	DNA topoisomerase II activity
BVD85_RS03600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BVD85_RS03610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVD85_RS03630	COG0539	negative regulation of cytoplasmic translation
BVD85_RS03655	COG1104	cysteine desulfurase activity
BVD85_RS03660	COG0301	tRNA thio-modification
BVD85_RS03665	COG1114	Component of the transport system for branched-chain amino acids
BVD85_RS03670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BVD85_RS03675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BVD85_RS03695	COG0564	pseudouridine synthase activity
BVD85_RS03700	COG2824	Alkylphosphonate utilization operon protein PhnA
BVD85_RS03710	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BVD85_RS03715	COG0540	Belongs to the ATCase OTCase family
BVD85_RS03720	COG0505	Belongs to the CarA family
BVD85_RS03730	COG2521	methyltransferase
BVD85_RS03730	COG2136	Putative SAM-dependent methyltransferase
BVD85_RS03735	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BVD85_RS03745	COG0228	four-way junction DNA binding
BVD85_RS03760	COG1132	(ABC) transporter
BVD85_RS03765	COG0726	polysaccharide deacetylase
BVD85_RS03770	COG0460	homoserine dehydrogenase
BVD85_RS03775	COG0083	homoserine kinase activity
BVD85_RS03780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BVD85_RS03785	COG3842	ATPase activity
BVD85_RS03790	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVD85_RS03795	COG1177	transmembrane transport
BVD85_RS03805	COG0038	chloride channel
BVD85_RS03825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVD85_RS03830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVD85_RS03845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BVD85_RS03850	COG0336	Belongs to the RNA methyltransferase TrmD family
BVD85_RS03855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVD85_RS03860	COG1349	DNA-binding transcription factor activity
BVD85_RS03865	COG1105	Belongs to the carbohydrate kinase PfkB family
BVD85_RS03870	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVD85_RS03870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVD85_RS03870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVD85_RS03880	COG1307	EDD domain protein, DegV family
BVD85_RS03885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BVD85_RS03890	COG0617	tRNA 3'-terminal CCA addition
BVD85_RS03895	COG0488	(ABC) transporter
BVD85_RS03905	COG1940	carbohydrate kinase activity
BVD85_RS03920	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BVD85_RS03925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BVD85_RS03935	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BVD85_RS03955	COG0481	GTPase activity
BVD85_RS03980	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BVD85_RS03985	COG2890	protein-(glutamine-N5) methyltransferase activity
BVD85_RS03990	COG0009	L-threonylcarbamoyladenylate synthase
BVD85_RS04000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BVD85_RS04010	COG0741	lytic transglycosylase activity
BVD85_RS04015	COG4221	oxidoreductase activity
BVD85_RS04040	COG1401	restriction endodeoxyribonuclease activity
BVD85_RS04045	COG4268	DNA restriction-modification system
BVD85_RS04115	COG2188	Transcriptional regulator
BVD85_RS04120	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BVD85_RS04125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVD85_RS04140	COG1660	Displays ATPase and GTPase activities
BVD85_RS04150	COG4974	Belongs to the 'phage' integrase family
BVD85_RS04165	COG0745	RESPONSE REGULATOR receiver
BVD85_RS04185	COG1136	(ABC) transporter
BVD85_RS04225	COG2382	esterase
BVD85_RS04235	COG2207	Transcriptional regulator
BVD85_RS04235	COG3708	Transcriptional regulator
BVD85_RS04240	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BVD85_RS04245	COG0647	UMP catabolic process
BVD85_RS04250	COG4974	Belongs to the 'phage' integrase family
BVD85_RS04260	COG1396	sequence-specific DNA binding
BVD85_RS04285	COG1131	(ABC) transporter
BVD85_RS04290	COG1132	(ABC) transporter
BVD85_RS04305	COG3843	relaxase mobilization nuclease domain protein
BVD85_RS04380	COG0791	NLP P60 protein
BVD85_RS04380	COG0741	lytic transglycosylase activity
BVD85_RS04410	COG2946	Replication initiation factor
BVD85_RS04420	COG1674	ftsk spoiiie
BVD85_RS04445	COG0542	response to heat
BVD85_RS04450	COG1396	sequence-specific DNA binding
BVD85_RS04480	COG2197	response regulator
BVD85_RS04505	COG1132	(ABC) transporter
BVD85_RS04540	COG2226	methyltransferase
BVD85_RS04550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVD85_RS04665	COG0270	DNA (cytosine-5-)-methyltransferase activity
BVD85_RS04680	COG0222	ribosome binding
BVD85_RS04685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BVD85_RS04690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVD85_RS04695	COG0758	DNA mediated transformation
BVD85_RS04700	COG0110	maltose O-acetyltransferase activity
BVD85_RS04705	COG1937	Protein conserved in bacteria
BVD85_RS04715	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVD85_RS04725	COG1272	protein, Hemolysin III
BVD85_RS04735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BVD85_RS04740	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BVD85_RS04755	COG0737	Belongs to the 5'-nucleotidase family
BVD85_RS04765	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BVD85_RS04770	COG0463	Glycosyl transferase, family 2
BVD85_RS04780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BVD85_RS04785	COG0284	orotidine-5'-phosphate decarboxylase activity
BVD85_RS04790	COG0167	dihydroorotate dehydrogenase activity
BVD85_RS04815	COG0297	glycogen (starch) synthase activity
BVD85_RS04825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD85_RS04830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD85_RS04845	COG3583	domain protein
BVD85_RS04870	COG1126	abc transporter atp-binding protein
BVD85_RS04880	COG0488	(ABC) transporter
BVD85_RS04885	COG2873	o-acetylhomoserine
BVD85_RS04910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVD85_RS04910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVD85_RS04920	COG3711	transcriptional antiterminator
BVD85_RS04925	COG3684	Belongs to the aldolase LacD family
BVD85_RS04935	COG0698	ribose 5-phosphate isomerase
BVD85_RS04940	COG0698	ribose 5-phosphate isomerase
BVD85_RS04950	COG1349	DNA-binding transcription factor activity
BVD85_RS04985	COG1396	sequence-specific DNA binding
BVD85_RS04990	COG1194	a g-specific adenine glycosylase
BVD85_RS05000	COG1132	(ABC) transporter
BVD85_RS05005	COG1132	(ABC) transporter
BVD85_RS05010	COG0280	phosphate acetyltransferase
BVD85_RS05015	COG0564	pseudouridine synthase activity
BVD85_RS05020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVD85_RS05025	COG2357	RelA SpoT domain protein
BVD85_RS05030	COG4116	CYTH
BVD85_RS05040	COG1104	cysteine desulfurase activity
BVD85_RS05055	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BVD85_RS05060	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVD85_RS05070	COG3764	Sortase (surface protein transpeptidase)
BVD85_RS05075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BVD85_RS05080	COG0039	L-malate dehydrogenase activity
BVD85_RS05090	COG1079	Belongs to the binding-protein-dependent transport system permease family
BVD85_RS05095	COG4603	Belongs to the binding-protein-dependent transport system permease family
BVD85_RS05100	COG3845	ABC transporter
BVD85_RS05105	COG1744	ABC transporter substrate-binding protein PnrA-like
BVD85_RS05120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BVD85_RS05125	COG2813	Specifically methylates the guanine in position
BVD85_RS05130	COG1072	(Pantothenic acid kinase))
BVD85_RS05160	COG5002	protein histidine kinase activity
BVD85_RS05165	COG0745	RESPONSE REGULATOR receiver
BVD85_RS05180	COG0704	Plays a role in the regulation of phosphate uptake
BVD85_RS05185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVD85_RS05190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVD85_RS05195	COG0581	inorganic phosphate transmembrane transporter activity
BVD85_RS05200	COG0573	inorganic phosphate transmembrane transporter activity
BVD85_RS05210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVD85_RS05210	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BVD85_RS05215	COG0483	inositol monophosphate 1-phosphatase activity
BVD85_RS05220	COG4476	Belongs to the UPF0223 family
BVD85_RS05225	COG1393	Belongs to the ArsC family
BVD85_RS05230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVD85_RS05235	COG0196	riboflavin kinase activity
BVD85_RS05240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BVD85_RS05305	COG0561	phosphatase activity
BVD85_RS05310	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVD85_RS05345	COG3759	membrane
BVD85_RS05350	COG1846	Transcriptional regulator
BVD85_RS05365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVD85_RS05370	COG2610	gluconate transmembrane transporter activity
BVD85_RS05390	COG0302	gtp cyclohydrolase
BVD85_RS05395	COG1051	belongs to the nudix hydrolase family
BVD85_RS05420	COG0072	phenylalanine-tRNA ligase activity
BVD85_RS05420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD85_RS05450	COG1028	Short-chain dehydrogenase reductase Sdr
BVD85_RS05455	COG1312	Catalyzes the dehydration of D-mannonate
BVD85_RS05465	COG0800	Aldolase
BVD85_RS05475	COG3250	beta-galactosidase activity
BVD85_RS05485	COG2211	Major facilitator Superfamily
BVD85_RS05500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVD85_RS05510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BVD85_RS05515	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BVD85_RS05520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BVD85_RS05525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BVD85_RS05530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BVD85_RS05535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BVD85_RS05540	COG0356	it plays a direct role in the translocation of protons across the membrane
BVD85_RS05550	COG1597	lipid kinase activity
BVD85_RS05560	COG0701	Predicted permease
BVD85_RS05565	COG3689	TIGRFAM TIGR03943 family protein
BVD85_RS05570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVD85_RS05585	COG0552	protein localization to endoplasmic reticulum
BVD85_RS05590	COG0561	phosphatase activity
BVD85_RS05595	COG0561	phosphatase activity
BVD85_RS05600	COG1196	nuclear chromosome segregation
BVD85_RS05625	COG2826	transposase and inactivated derivatives, IS30 family
BVD85_RS05640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVD85_RS05645	COG0538	isocitrate dehydrogenase activity
BVD85_RS05650	COG0372	Belongs to the citrate synthase family
BVD85_RS05655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BVD85_RS05660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVD85_RS05665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVD85_RS05675	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVD85_RS05680	COG1609	Transcriptional regulator
BVD85_RS05695	COG5492	domain, Protein
BVD85_RS05700	COG5492	domain, Protein
BVD85_RS05705	COG5492	domain, Protein
BVD85_RS05715	COG3716	PTS system mannose fructose sorbose family IID component
BVD85_RS05725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVD85_RS05730	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BVD85_RS05755	COG1028	Short-chain dehydrogenase reductase Sdr
BVD85_RS05795	COG1476	TRANSCRIPTIONal
BVD85_RS05820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVD85_RS05830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVD85_RS05835	COG4122	O-methyltransferase activity
BVD85_RS05860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD85_RS05860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD85_RS05870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVD85_RS05875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVD85_RS05880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BVD85_RS05885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BVD85_RS05895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD85_RS05895	COG1116	anion transmembrane transporter activity
BVD85_RS05900	COG4120	Belongs to the binding-protein-dependent transport system permease family
BVD85_RS05920	COG3684	Belongs to the aldolase LacD family
BVD85_RS05930	COG3679	Belongs to the UPF0342 family
BVD85_RS05935	COG0287	Prephenate dehydrogenase
BVD85_RS05940	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BVD85_RS05945	COG0710	3-dehydroquinate dehydratase activity
BVD85_RS05950	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVD85_RS05955	COG1368	sulfuric ester hydrolase activity
BVD85_RS05975	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BVD85_RS05985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BVD85_RS06030	COG1216	Glycosyl transferase, family 2
BVD85_RS06030	COG1442	glycosyl transferase family 8
BVD85_RS06035	COG1442	glycosyl transferase family 8
BVD85_RS06065	COG0463	Glycosyl transferase, family 2
BVD85_RS06095	COG1091	dTDP-4-dehydrorhamnose reductase activity
BVD85_RS06100	COG1088	dTDP-glucose 4,6-dehydratase activity
BVD85_RS06115	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BVD85_RS06125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVD85_RS06130	COG2384	SAM-dependent methyltransferase
BVD85_RS06145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVD85_RS06160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVD85_RS06160	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BVD85_RS06165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVD85_RS06175	COG0300	oxidoreductase activity
BVD85_RS06180	COG1234	tRNA 3'-trailer cleavage
BVD85_RS06190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVD85_RS06195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BVD85_RS06205	COG2807	transmembrane transport
BVD85_RS06210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BVD85_RS06215	COG1702	phosphate starvation-inducible protein PhoH
BVD85_RS06220	COG4479	Belongs to the UPF0346 family
BVD85_RS06235	COG2996	Protein conserved in bacteria
BVD85_RS06240	COG0233	cytoplasmic translational termination
BVD85_RS06245	COG0528	UMP kinase activity
BVD85_RS06250	COG2244	polysaccharide biosynthetic process
BVD85_RS06255	COG0625	glutathione transferase activity
BVD85_RS06280	COG0346	lactoylglutathione lyase activity
BVD85_RS06285	COG1674	ftsk spoiiie
BVD85_RS06285	COG0697	spore germination
BVD85_RS06290	COG1621	beta-fructofuranosidase activity
BVD85_RS06300	COG0395	ABC-type sugar transport system, permease component
BVD85_RS06305	COG4209	transmembrane transport
BVD85_RS06310	COG1609	Transcriptional regulator
BVD85_RS06330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVD85_RS06345	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BVD85_RS06355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVD85_RS06365	COG1181	Belongs to the D-alanine--D-alanine ligase family
BVD85_RS06370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BVD85_RS06375	COG0768	penicillin binding
BVD85_RS06385	COG0488	(ABC) transporter
BVD85_RS06390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BVD85_RS06400	COG0745	RESPONSE REGULATOR receiver
BVD85_RS06405	COG1126	abc transporter atp-binding protein
BVD85_RS06410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD85_RS06415	COG0765	amino acid transport
BVD85_RS06420	COG0765	amino acid transport
BVD85_RS06425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BVD85_RS06440	COG0438	transferase activity, transferring glycosyl groups
BVD85_RS06455	COG1609	Transcriptional regulator
BVD85_RS06465	COG0343	queuine tRNA-ribosyltransferase activity
BVD85_RS06475	COG1832	CoA-binding protein
BVD85_RS06485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVD85_RS06485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVD85_RS06500	COG1136	(ABC) transporter
BVD85_RS06510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BVD85_RS06515	COG2217	Heavy metal translocating P-type atpase
BVD85_RS06530	COG1063	alcohol dehydrogenase
BVD85_RS06535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BVD85_RS06540	COG0557	exoribonuclease II activity
BVD85_RS06545	COG0017	Asparaginyl-tRNA synthetase
BVD85_RS06555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVD85_RS06560	COG2814	Major facilitator Superfamily
BVD85_RS06570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BVD85_RS06575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVD85_RS06580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BVD85_RS06590	COG1737	Transcriptional regulator
BVD85_RS06600	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BVD85_RS06610	COG1011	Hydrolase
BVD85_RS06615	COG1132	(ABC) transporter
BVD85_RS06620	COG1132	(ABC) transporter
BVD85_RS06645	COG2177	Part of the ABC transporter FtsEX involved in
BVD85_RS06650	COG2884	Cell division ATP-binding protein ftsE
BVD85_RS06655	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BVD85_RS06665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVD85_RS06695	COG2826	transposase and inactivated derivatives, IS30 family
BVD85_RS06730	COG2151	metal-sulfur cluster biosynthetic enzyme
BVD85_RS06735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVD85_RS06740	COG0358	DNA primase activity
BVD85_RS06745	COG1970	mechanosensitive ion channel activity
BVD85_RS06750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVD85_RS06755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BVD85_RS06765	COG0647	UMP catabolic process
BVD85_RS06770	COG1051	belongs to the nudix hydrolase family
BVD85_RS06780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVD85_RS06795	COG0813	purine-nucleoside phosphorylase activity
BVD85_RS06800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BVD85_RS06810	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BVD85_RS06815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BVD85_RS06820	COG0732	type I restriction modification DNA specificity domain
BVD85_RS06840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BVD85_RS06855	COG2268	Band 7 protein
BVD85_RS06860	COG1704	LemA family
BVD85_RS06870	COG1573	uracil-dna glycosylase
BVD85_RS06905	COG2226	methyltransferase
BVD85_RS06910	COG0488	(ABC) transporter
BVD85_RS06915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVD85_RS06930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVD85_RS06935	COG3442	glutamine amidotransferase
BVD85_RS06945	COG2226	methyltransferase
BVD85_RS06965	COG0488	(ABC) transporter
BVD85_RS07000	COG3842	ATPase activity
BVD85_RS07020	COG1263	PTS System
BVD85_RS07020	COG2190	(PTS) system
BVD85_RS07020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVD85_RS07025	COG3711	transcriptional antiterminator
BVD85_RS07030	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BVD85_RS07035	COG3527	Alpha-acetolactate decarboxylase
BVD85_RS07045	COG0628	permease
BVD85_RS07050	COG2706	6-phosphogluconolactonase activity
BVD85_RS07060	COG1011	Hydrolase
BVD85_RS07105	COG0560	Phosphoserine phosphatase
BVD85_RS07110	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BVD85_RS07115	COG0187	DNA topoisomerase II activity
BVD85_RS07120	COG0693	protein deglycase activity
BVD85_RS07125	COG0772	Belongs to the SEDS family
BVD85_RS07130	COG0582	viral genome integration into host DNA
BVD85_RS07215	COG0582	viral genome integration into host DNA
BVD85_RS07230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BVD85_RS07235	COG0716	FMN binding
BVD85_RS07245	COG0287	Prephenate dehydrogenase
BVD85_RS07245	COG1605	Chorismate mutase
BVD85_RS07250	COG0038	chloride channel
BVD85_RS07260	COG0737	Belongs to the 5'-nucleotidase family
BVD85_RS07265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVD85_RS07270	COG1466	dna polymerase III delta subunit
BVD85_RS07305	COG0683	leucine binding
BVD85_RS07320	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BVD85_RS07325	COG0366	Alpha amylase catalytic
BVD85_RS07335	COG0395	ABC-type sugar transport system, permease component
BVD85_RS07340	COG1175	transmembrane transport
BVD85_RS07345	COG1653	transport
BVD85_RS07355	COG2207	Transcriptional regulator
BVD85_RS07360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BVD85_RS07365	COG0626	cystathionine gamma-synthase activity
BVD85_RS07385	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BVD85_RS07390	COG2827	Endonuclease containing a URI domain
BVD85_RS07415	COG0640	Transcriptional regulator
BVD85_RS07420	COG0513	Belongs to the DEAD box helicase family
BVD85_RS07430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVD85_RS07470	COG0494	nUDIX hydrolase
BVD85_RS07475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BVD85_RS07490	COG1028	Short-chain dehydrogenase reductase Sdr
BVD85_RS07520	COG0577	efflux transmembrane transporter activity
BVD85_RS07525	COG1136	(ABC) transporter
BVD85_RS07530	COG2205	protein histidine kinase activity
BVD85_RS07545	COG0436	Aminotransferase
BVD85_RS07555	COG1174	glycine betaine transport
BVD85_RS07560	COG0517	IMP dehydrogenase activity
BVD85_RS07560	COG1125	glycine betaine transport
BVD85_RS07580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BVD85_RS07585	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BVD85_RS07590	COG1482	cell wall glycoprotein biosynthetic process
BVD85_RS07620	COG3091	SprT-like family
BVD85_RS07625	COG2183	response to ionizing radiation
BVD85_RS07630	COG0656	L-ascorbic acid biosynthetic process
BVD85_RS07635	COG4708	membrane
BVD85_RS07640	COG2246	polysaccharide biosynthetic process
BVD85_RS07650	COG0024	Methionine aminopeptidase
BVD85_RS07660	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVD85_RS07665	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVD85_RS07670	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BVD85_RS07675	COG2131	deaminase
BVD85_RS07685	COG1363	Peptidase, m42
BVD85_RS07700	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVD85_RS07705	COG1956	GAF domain-containing protein
BVD85_RS07715	COG1695	Transcriptional regulator
BVD85_RS07730	COG0513	Belongs to the DEAD box helicase family
BVD85_RS07735	COG0726	polysaccharide deacetylase
BVD85_RS07755	COG0183	Belongs to the thiolase family
BVD85_RS07760	COG3425	synthase
BVD85_RS07790	COG0776	regulation of translation
BVD85_RS07800	COG2755	lipolytic protein G-D-S-L family
BVD85_RS07805	COG1307	EDD domain protein, DegV family
BVD85_RS07810	COG0497	DNA recombination
BVD85_RS07815	COG1438	arginine binding
BVD85_RS07820	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BVD85_RS07830	COG1722	exodeoxyribonuclease VII activity
BVD85_RS07835	COG1570	exodeoxyribonuclease VII activity
BVD85_RS07840	COG2321	neutral zinc metallopeptidase
BVD85_RS07845	COG1755	Isoprenylcysteine carboxyl methyltransferase
BVD85_RS07850	COG5002	protein histidine kinase activity
BVD85_RS07855	COG0745	RESPONSE REGULATOR receiver
BVD85_RS07875	COG1227	inorganic diphosphatase activity
BVD85_RS07885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BVD85_RS07890	COG1253	flavin adenine dinucleotide binding
BVD85_RS07895	COG1119	ATPase activity
BVD85_RS07900	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BVD85_RS07910	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BVD85_RS07915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BVD85_RS07930	COG4470	Protein conserved in bacteria
BVD85_RS07935	COG3480	Lon protease (S16) C-terminal proteolytic domain
BVD85_RS07940	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BVD85_RS07945	COG0742	ribosomal rna small subunit methyltransferase
BVD85_RS07955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVD85_RS07960	COG4483	Protein conserved in bacteria
BVD85_RS07965	COG2197	response regulator
BVD85_RS07970	COG2203	Gaf domain
BVD85_RS07970	COG4585	Histidine kinase
BVD85_RS07975	COG0842	Transport permease protein
BVD85_RS07980	COG1131	(ABC) transporter
BVD85_RS07995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVD85_RS08010	COG0671	phosphoesterase, PA-phosphatase related
BVD85_RS08015	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BVD85_RS08030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BVD85_RS08035	COG1187	pseudouridine synthase activity
BVD85_RS08040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BVD85_RS08045	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BVD85_RS08050	COG0582	viral genome integration into host DNA
BVD85_RS08070	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVD85_RS08075	COG3763	UPF0154 protein
BVD85_RS08085	COG3579	cysteine-type endopeptidase activity
BVD85_RS08100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVD85_RS08105	COG1254	Belongs to the acylphosphatase family
BVD85_RS08115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVD85_RS08120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVD85_RS08130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVD85_RS08140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVD85_RS08155	COG1160	GTP binding
BVD85_RS08165	COG0778	Nitroreductase
BVD85_RS08170	COG1484	DNA-dependent DNA replication
BVD85_RS08180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BVD85_RS08185	COG0628	permease
BVD85_RS08190	COG0745	RESPONSE REGULATOR receiver
BVD85_RS08195	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BVD85_RS08205	COG0492	ferredoxin-NADP+ reductase activity
BVD85_RS08215	COG0513	Belongs to the DEAD box helicase family
BVD85_RS08225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVD85_RS08230	COG0768	penicillin binding
BVD85_RS08240	COG0275	rRNA processing
BVD85_RS08290	COG4939	FMN-binding domain protein
BVD85_RS08295	COG0142	geranyltranstransferase activity
BVD85_RS08300	COG1252	NADH dehydrogenase
BVD85_RS08315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVD85_RS08320	COG0569	domain protein
BVD85_RS08325	COG0534	Mate efflux family protein
BVD85_RS08335	COG4224	UPF0291 protein
BVD85_RS08340	COG0751	glycine-tRNA ligase activity
BVD85_RS08365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVD85_RS08370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVD85_RS08375	COG1464	Belongs to the NlpA lipoprotein family
BVD85_RS08380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVD85_RS08385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BVD85_RS08390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVD85_RS08395	COG2252	PERMEase
BVD85_RS08400	COG0561	phosphatase activity
BVD85_RS08410	COG3715	PTS system
BVD85_RS08415	COG3716	PTS system mannose fructose sorbose family IID component
BVD85_RS08440	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BVD85_RS08485	COG0439	Biotin carboxylase
BVD85_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
BVD85_RS08510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVD85_RS08515	COG2070	2-Nitropropane dioxygenase
BVD85_RS08525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVD85_RS08535	COG1024	Enoyl-CoA hydratase
BVD85_RS08540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVD85_RS08545	COG0527	aspartate kinase activity
BVD85_RS08560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVD85_RS08565	COG0736	holo-[acyl-carrier-protein] synthase activity
BVD85_RS08570	COG0653	protein targeting
BVD85_RS08580	COG1940	carbohydrate kinase activity
BVD85_RS08585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVD85_RS08585	COG2190	(PTS) system
BVD85_RS08585	COG1263	PTS System
BVD85_RS08590	COG1621	beta-fructofuranosidase activity
BVD85_RS08595	COG1609	Transcriptional regulator
BVD85_RS08600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVD85_RS08615	COG0006	proline dipeptidase activity
BVD85_RS08620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BVD85_RS08640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BVD85_RS08645	COG0629	single-stranded DNA binding
BVD85_RS08655	COG2826	transposase and inactivated derivatives, IS30 family
BVD85_RS08660	COG0095	Lipoate-protein ligase
BVD85_RS08675	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVD85_RS08680	COG0022	dehydrogenase e1 component
BVD85_RS08680	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVD85_RS08685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVD85_RS08690	COG2860	membrane
BVD85_RS08705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BVD85_RS08710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BVD85_RS08720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BVD85_RS08725	COG0195	Participates in both transcription termination and antitermination
BVD85_RS08740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BVD85_RS08750	COG4473	ABC transporter
BVD85_RS08755	COG1131	(ABC) transporter
BVD85_RS08760	COG0537	adenosine 5'-monophosphoramidase activity
BVD85_RS08770	COG1316	TRANSCRIPTIONal
BVD85_RS08780	COG0802	atpase or kinase
BVD85_RS08785	COG1461	Dihydroxyacetone kinase
BVD85_RS08800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVD85_RS08805	COG0601	transmembrane transport
BVD85_RS08810	COG4608	Belongs to the ABC transporter superfamily
BVD85_RS08825	COG1686	Belongs to the peptidase S11 family
BVD85_RS08840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVD85_RS08845	COG0719	Fe-S assembly protein
BVD85_RS08855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVD85_RS08860	COG4862	establishment of competence for transformation
BVD85_RS08865	COG1968	undecaprenyl-diphosphatase activity
BVD85_RS08870	COG0765	amino acid transport
BVD85_RS08890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVD85_RS08895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVD85_RS08900	COG0440	acetolactate synthase activity
BVD85_RS08905	COG0028	Belongs to the TPP enzyme family
BVD85_RS08925	COG0129	dihydroxy-acid dehydratase activity
BVD85_RS08935	COG2151	metal-sulfur cluster biosynthetic enzyme
BVD85_RS08950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BVD85_RS08965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVD85_RS08990	COG3842	ATPase activity
BVD85_RS09000	COG2207	Transcriptional regulator
BVD85_RS09000	COG4753	response regulator
BVD85_RS09005	COG2972	Histidine kinase
BVD85_RS09025	COG1653	transport
BVD85_RS09030	COG0395	ABC-type sugar transport system, permease component
BVD85_RS09035	COG1175	transmembrane transport
BVD85_RS09050	COG0383	alpha-mannosidase activity
BVD85_RS09070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BVD85_RS09090	COG1045	serine acetyltransferase
BVD85_RS09095	COG1185	polyribonucleotide nucleotidyltransferase activity
BVD85_RS09120	COG1263	PTS System
BVD85_RS09120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVD85_RS09130	COG1737	Transcriptional regulator
BVD85_RS09135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BVD85_RS09155	COG1187	pseudouridine synthase activity
BVD85_RS09175	COG0242	peptide deformylase activity
BVD85_RS09185	COG0066	3-isopropylmalate dehydratase activity
BVD85_RS09210	COG2309	aminopeptidase activity
BVD85_RS09225	COG2176	DNA-directed DNA polymerase activity
BVD85_RS09230	COG2376	Dihydroxyacetone kinase
BVD85_RS09240	COG2376	Dihydroxyacetone kinase
BVD85_RS09245	COG1461	Dihydroxyacetone kinase
BVD85_RS09250	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BVD85_RS09255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BVD85_RS09260	COG0442	prolyl-tRNA aminoacylation
BVD85_RS09270	COG4589	Belongs to the CDS family
BVD85_RS09275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BVD85_RS09280	COG1862	Preprotein translocase
BVD85_RS09290	COG1181	Belongs to the D-alanine--D-alanine ligase family
BVD85_RS09290	COG2918	glutathione biosynthetic process
BVD85_RS09300	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BVD85_RS09305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVD85_RS09320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BVD85_RS09330	COG4463	regulation of RNA biosynthetic process
BVD85_RS09345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BVD85_RS09380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVD85_RS09385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVD85_RS09390	COG0492	ferredoxin-NADP+ reductase activity
BVD85_RS09395	COG0564	pseudouridine synthase activity
BVD85_RS09400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVD85_RS09420	COG1564	THIamine pyrophosphokinase
BVD85_RS09430	COG1162	GTPase activity
BVD85_RS09480	COG4115	mRNA cleavage
BVD85_RS09515	COG0084	hydrolase, TatD family'
BVD85_RS09525	COG1847	R3H domain protein
BVD85_RS09535	COG0594	ribonuclease P activity
BVD85_RS09540	COG0165	Argininosuccinate lyase
BVD85_RS09545	COG0137	argininosuccinate synthase activity
BVD85_RS09555	COG1827	regulation of RNA biosynthetic process
BVD85_RS09570	COG2040	homocysteine
BVD85_RS09575	COG0833	amino acid
BVD85_RS09620	COG0756	dUTP diphosphatase activity
BVD85_RS09625	COG1132	(ABC) transporter
BVD85_RS09630	COG1132	(ABC) transporter
BVD85_RS09640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BVD85_RS09645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVD85_RS09650	COG0705	Rhomboid family
BVD85_RS09655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVD85_RS09660	COG1473	amidohydrolase
BVD85_RS09665	COG2171	N-acyltransferase activity
BVD85_RS09680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BVD85_RS09705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVD85_RS09730	COG3623	hexulose-6-phosphate isomerase
BVD85_RS09755	COG1523	belongs to the glycosyl hydrolase 13 family
BVD85_RS09760	COG1609	Transcriptional regulator
BVD85_RS09765	COG1126	abc transporter atp-binding protein
BVD85_RS09770	COG0765	amino acid transport
BVD85_RS09775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD85_RS09780	COG3942	CHAP domain
BVD85_RS09785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BVD85_RS09795	COG1447	Phosphotransferase system cellobiose-specific component IIA
BVD85_RS09805	COG3711	transcriptional antiterminator
BVD85_RS09805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVD85_RS09815	COG2723	6-phospho-beta-galactosidase activity
BVD85_RS09820	COG1486	melibiose metabolic process
BVD85_RS09830	COG3590	peptidase
BVD85_RS09835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVD85_RS09840	COG1321	iron dependent repressor
BVD85_RS09840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVD85_RS09845	COG1121	(ABC) transporter
BVD85_RS09860	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVD85_RS09895	COG1490	D-aminoacyl-tRNA deacylase activity
BVD85_RS09905	COG0737	Belongs to the 5'-nucleotidase family
BVD85_RS09965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVD85_RS09990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVD85_RS10020	COG0737	Belongs to the 5'-nucleotidase family
BVD85_RS10030	COG1328	CTP reductase activity
BVD85_RS10060	COG1438	arginine binding
BVD85_RS10065	COG0018	arginyl-trna synthetase
BVD85_RS10085	COG1640	4-alpha-glucanotransferase
BVD85_RS10090	COG2182	Extracellular solute-binding protein
BVD85_RS10095	COG1175	transmembrane transport
BVD85_RS10100	COG3833	ABC-type maltose transport systems, permease component
BVD85_RS10105	COG5521	maltodextrose utilization protein MalA
BVD85_RS10110	COG1609	Transcriptional regulator
BVD85_RS10115	COG1523	belongs to the glycosyl hydrolase 13 family
BVD85_RS10120	COG1780	Probably involved in ribonucleotide reductase function
BVD85_RS10125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVD85_RS10130	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BVD85_RS10135	COG2153	protein acetylation
BVD85_RS10140	COG4989	oxidoreductase activity
BVD85_RS10145	COG1216	Glycosyl transferase, family 2
BVD85_RS10150	COG1472	Belongs to the glycosyl hydrolase 3 family
BVD85_RS10190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BVD85_RS10205	COG0305	Participates in initiation and elongation during chromosome replication
BVD85_RS10210	COG0359	binds to the 23S rRNA
BVD85_RS10220	COG0445	tRNA wobble uridine modification
BVD85_RS10235	COG1051	belongs to the nudix hydrolase family
BVD85_RS10240	COG1733	regulation of RNA biosynthetic process
BVD85_RS10250	COG0482	sulfurtransferase activity
BVD85_RS10255	COG1760	l-serine dehydratase
BVD85_RS10260	COG1760	l-serine dehydratase
BVD85_RS10270	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BVD85_RS10275	COG1122	ATPase activity
BVD85_RS10280	COG1122	ATPase activity
BVD85_RS10285	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BVD85_RS10290	COG1426	Protein conserved in bacteria
BVD85_RS10295	COG0612	Peptidase, M16
BVD85_RS10300	COG0612	Peptidase, M16
BVD85_RS10310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BVD85_RS10315	COG0517	IMP dehydrogenase activity
BVD85_RS10315	COG0516	GMP reductase activity
BVD85_RS10325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVD85_RS10330	COG0488	(ABC) transporter
BVD85_RS10360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BVD85_RS10365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVD85_RS10370	COG1475	DNA binding
BVD85_RS10375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BVD85_RS10380	COG0592	DNA-directed DNA polymerase activity
BVD85_RS10400	COG0012	GTP binding
BVD85_RS10405	COG0193	aminoacyl-tRNA hydrolase activity
BVD85_RS10410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVD85_RS10415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BVD85_RS10435	COG0037	tRNA processing
BVD85_RS10445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins