locus-tag	class	description
NKZ63_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NKZ63_RS00010	COG0592	DNA-directed DNA polymerase activity
NKZ63_RS00030	COG0012	GTP binding
NKZ63_RS00035	COG0193	aminoacyl-tRNA hydrolase activity
NKZ63_RS00040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NKZ63_RS00045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NKZ63_RS00065	COG0037	tRNA processing
NKZ63_RS00075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NKZ63_RS00190	COG1792	Involved in formation and maintenance of cell shape
NKZ63_RS00205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NKZ63_RS00210	COG0436	Aminotransferase
NKZ63_RS00215	COG1381	Involved in DNA repair and RecF pathway recombination
NKZ63_RS00220	COG0416	fatty acid biosynthetic process
NKZ63_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKZ63_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKZ63_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NKZ63_RS00255	COG0138	bifunctional purine biosynthesis protein purh
NKZ63_RS00280	COG0151	Belongs to the GarS family
NKZ63_RS00285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NKZ63_RS00300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NKZ63_RS00335	COG2255	four-way junction helicase activity
NKZ63_RS00345	COG0546	phosphoglycolate phosphatase activity
NKZ63_RS00360	COG0285	dihydrofolate synthase activity
NKZ63_RS00370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NKZ63_RS00375	COG0632	four-way junction helicase activity
NKZ63_RS00380	COG0519	Catalyzes the synthesis of GMP from XMP
NKZ63_RS00395	COG1393	Belongs to the ArsC family
NKZ63_RS00400	COG4472	Bacterial protein of unknown function (DUF965)
NKZ63_RS00405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NKZ63_RS00410	COG3906	Belongs to the UPF0473 family
NKZ63_RS00425	COG0051	transcription antitermination factor activity, RNA binding
NKZ63_RS00430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NKZ63_RS00435	COG0088	Forms part of the polypeptide exit tunnel
NKZ63_RS00440	COG0089	rRNA binding
NKZ63_RS00445	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NKZ63_RS00450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NKZ63_RS00455	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NKZ63_RS00460	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NKZ63_RS00465	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NKZ63_RS00470	COG0255	Belongs to the universal ribosomal protein uL29 family
NKZ63_RS00475	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NKZ63_RS00480	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NKZ63_RS00485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NKZ63_RS00490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NKZ63_RS00495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NKZ63_RS00500	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NKZ63_RS00505	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NKZ63_RS00510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NKZ63_RS00515	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NKZ63_RS00520	COG1841	ribosomal large subunit assembly
NKZ63_RS00530	COG0201	protein transport
NKZ63_RS00535	COG0563	adenylate kinase activity
NKZ63_RS00540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NKZ63_RS00545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NKZ63_RS00550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NKZ63_RS00560	COG0202	RNA polymerase activity
NKZ63_RS00670	COG0582	viral genome integration into host DNA
NKZ63_RS00680	COG2946	Replication initiation factor
NKZ63_RS00690	COG1674	ftsk spoiiie
NKZ63_RS00730	COG1121	(ABC) transporter
NKZ63_RS00735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NKZ63_RS00740	COG0803	Belongs to the bacterial solute-binding protein 9 family
NKZ63_RS00740	COG3443	Belongs to the bacterial solute-binding protein 9 family
NKZ63_RS00765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NKZ63_RS00770	COG0085	RNA polymerase activity
NKZ63_RS00775	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKZ63_RS00785	COG1619	proteins homologs of microcin C7 resistance protein MccF
NKZ63_RS00790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NKZ63_RS00795	COG1459	type II secretion system
NKZ63_RS00800	COG4537	Required for transformation and DNA binding
NKZ63_RS00830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NKZ63_RS00840	COG0285	dihydrofolate synthase activity
NKZ63_RS00845	COG1363	Peptidase, m42
NKZ63_RS00855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NKZ63_RS00865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKZ63_RS00890	COG0459	protein refolding
NKZ63_RS00900	COG0049	tRNA binding
NKZ63_RS00905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NKZ63_RS00910	COG3590	peptidase
NKZ63_RS00920	COG0126	phosphoglycerate kinase activity
NKZ63_RS00930	COG0789	Transcriptional regulator
NKZ63_RS00935	COG0174	glutamine synthetase
NKZ63_RS00950	COG1214	PFAM Peptidase M22, glycoprotease
NKZ63_RS00960	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NKZ63_RS00965	COG2207	Transcriptional regulator
NKZ63_RS00975	COG1175	transmembrane transport
NKZ63_RS00980	COG0395	ABC-type sugar transport system, permease component
NKZ63_RS01000	COG2855	membrane
NKZ63_RS01010	COG1131	(ABC) transporter
NKZ63_RS01020	COG2081	HI0933 family
NKZ63_RS01025	COG2723	6-phospho-beta-galactosidase activity
NKZ63_RS01035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NKZ63_RS01050	COG3959	Transketolase, thiamine diphosphate binding domain
NKZ63_RS01055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NKZ63_RS01060	COG0584	glycerophosphoryl diester phosphodiesterase
NKZ63_RS01065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NKZ63_RS01070	COG2222	sugar isomerase
NKZ63_RS01090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NKZ63_RS01100	COG3942	CHAP domain
NKZ63_RS01105	COG1882	Formate acetyltransferase
NKZ63_RS01120	COG2910	NAD(P)H-binding
NKZ63_RS01145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NKZ63_RS01180	COG0363	glucosamine-6-phosphate deaminase activity
NKZ63_RS01185	COG2217	Heavy metal translocating P-type atpase
NKZ63_RS01190	COG2217	Heavy metal translocating P-type atpase
NKZ63_RS01200	COG2217	Heavy metal translocating P-type atpase
NKZ63_RS01205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NKZ63_RS01210	COG0681	Belongs to the peptidase S26 family
NKZ63_RS01230	COG0366	Alpha amylase catalytic
NKZ63_RS01235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NKZ63_RS01235	COG1263	PTS System
NKZ63_RS01240	COG2188	Transcriptional regulator
NKZ63_RS01255	COG1193	negative regulation of DNA recombination
NKZ63_RS01280	COG3118	belongs to the thioredoxin family
NKZ63_RS01290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKZ63_RS01290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKZ63_RS01345	COG1136	(ABC) transporter
NKZ63_RS01350	COG1115	amino acid carrier protein
NKZ63_RS01355	COG0668	transmembrane transport
NKZ63_RS01365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NKZ63_RS01370	COG0167	dihydroorotate dehydrogenase activity
NKZ63_RS01375	COG2843	Capsule synthesis protein
NKZ63_RS01380	COG0561	phosphatase activity
NKZ63_RS01395	COG1131	(ABC) transporter
NKZ63_RS01400	COG1309	transcriptional regulator
NKZ63_RS01405	COG1511	domain protein
NKZ63_RS01430	COG1346	cytolysis
NKZ63_RS01435	COG2116	formate transmembrane transporter activity
NKZ63_RS01440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NKZ63_RS01445	COG0433	COG0433 Predicted ATPase
NKZ63_RS01470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NKZ63_RS01475	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NKZ63_RS01485	COG3547	Transposase (IS116 IS110 IS902 family)
NKZ63_RS01490	COG0124	histidyl-tRNA synthetase
NKZ63_RS01495	COG1064	alcohol dehydrogenase
NKZ63_RS01500	COG1012	belongs to the aldehyde dehydrogenase family
NKZ63_RS01500	COG1454	alcohol dehydrogenase
NKZ63_RS01510	COG4988	ABC transporter
NKZ63_RS01515	COG1132	(ABC) transporter
NKZ63_RS01530	COG1129	ABC transporter
NKZ63_RS01535	COG0534	Mate efflux family protein
NKZ63_RS01540	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NKZ63_RS01555	COG1304	FMN binding
NKZ63_RS01560	COG1132	(ABC) transporter
NKZ63_RS01565	COG1132	(ABC) transporter
NKZ63_RS01570	COG3830	Belongs to the UPF0237 family
NKZ63_RS01575	COG2848	UPF0210 protein
NKZ63_RS01585	COG1420	regulation of RNA biosynthetic process
NKZ63_RS01590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NKZ63_RS01595	COG0443	Heat shock 70 kDa protein
NKZ63_RS01600	COG0484	heat shock protein binding
NKZ63_RS01605	COG0095	Lipoate-protein ligase
NKZ63_RS01615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NKZ63_RS01620	COG0765	amino acid transport
NKZ63_RS01635	COG3655	Transcriptional regulator
NKZ63_RS01645	COG2217	Heavy metal translocating P-type atpase
NKZ63_RS01670	COG4475	Protein of unknown function (DUF436)
NKZ63_RS01700	COG0446	pyridine nucleotide-disulphide oxidoreductase
NKZ63_RS01700	COG1902	pentaerythritol trinitrate reductase activity
NKZ63_RS01720	COG0544	peptidyl-prolyl cis-trans isomerase activity
NKZ63_RS01745	COG3343	RNA polymerase activity
NKZ63_RS01750	COG0504	CTP synthase activity
NKZ63_RS01765	COG0191	fructose-bisphosphate aldolase activity
NKZ63_RS01770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NKZ63_RS01810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NKZ63_RS01830	COG0589	response to stress
NKZ63_RS01835	COG0436	Aminotransferase
NKZ63_RS01840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NKZ63_RS01845	COG1335	isochorismatase
NKZ63_RS01855	COG0335	large ribosomal subunit rRNA binding
NKZ63_RS01865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKZ63_RS01870	COG0154	amidase activity
NKZ63_RS01875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKZ63_RS01885	COG1609	Transcriptional regulator
NKZ63_RS01890	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NKZ63_RS01895	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NKZ63_RS01905	COG3142	Participates in the control of copper homeostasis
NKZ63_RS01920	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NKZ63_RS01925	COG1534	Rna-binding protein
NKZ63_RS01930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NKZ63_RS01935	COG1713	HD superfamily hydrolase involved in NAD metabolism
NKZ63_RS01950	COG1335	isochorismatase
NKZ63_RS01955	COG0799	negative regulation of ribosome biogenesis
NKZ63_RS01960	COG2226	methyltransferase
NKZ63_RS01980	COG0789	Transcriptional regulator
NKZ63_RS01985	COG2348	transferase activity, transferring amino-acyl groups
NKZ63_RS01995	COG0242	peptide deformylase activity
NKZ63_RS02005	COG1640	4-alpha-glucanotransferase
NKZ63_RS02010	COG0058	SHG alpha-glucan phosphorylase activity
NKZ63_RS02025	COG2190	(PTS) system
NKZ63_RS02025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NKZ63_RS02025	COG1263	PTS System
NKZ63_RS02040	COG0217	transcriptional regulatory protein
NKZ63_RS02050	COG4720	Psort location CytoplasmicMembrane, score
NKZ63_RS02060	COG1054	Belongs to the UPF0176 family
NKZ63_RS02070	COG1122	ATPase activity
NKZ63_RS02085	COG0357	Ribosomal RNA small subunit methyltransferase G
NKZ63_RS02090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NKZ63_RS02095	COG3331	DNA recombination
NKZ63_RS02100	COG4474	Belongs to the UPF0398 family
NKZ63_RS02105	COG3599	regulation of cell shape
NKZ63_RS02115	COG0116	Belongs to the methyltransferase superfamily
NKZ63_RS02125	COG1854	S-ribosylhomocysteine lyase activity
NKZ63_RS02130	COG1418	mRNA catabolic process
NKZ63_RS02140	COG1758	RNA polymerase activity
NKZ63_RS02145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NKZ63_RS02150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NKZ63_RS02155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NKZ63_RS02155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NKZ63_RS02160	COG0631	protein serine/threonine phosphatase activity
NKZ63_RS02165	COG0515	serine threonine protein kinase
NKZ63_RS02165	COG2815	serine threonine protein kinase
NKZ63_RS02190	COG1098	S1 RNA binding domain
NKZ63_RS02200	COG1739	Uncharacterized protein family UPF0029
NKZ63_RS02205	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NKZ63_RS02295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKZ63_RS02305	COG3557	Belongs to the UPF0374 family
NKZ63_RS02315	COG2188	Transcriptional regulator
NKZ63_RS02320	COG2188	Transcriptional regulator
NKZ63_RS02330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NKZ63_RS02340	COG3716	PTS system mannose fructose sorbose family IID component
NKZ63_RS02350	COG2017	converts alpha-aldose to the beta-anomer
NKZ63_RS02365	COG0346	lactoylglutathione lyase activity
NKZ63_RS02400	COG0494	nUDIX hydrolase
NKZ63_RS02415	COG1217	gtp-binding protein TYPA
NKZ63_RS02430	COG0681	Belongs to the peptidase S26 family
NKZ63_RS02465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NKZ63_RS02480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NKZ63_RS02485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NKZ63_RS02490	COG1799	cell septum assembly
NKZ63_RS02505	COG3599	regulation of cell shape
NKZ63_RS02525	COG0406	alpha-ribazole phosphatase activity
NKZ63_RS02525	COG0494	nUDIX hydrolase
NKZ63_RS02530	COG0542	response to heat
NKZ63_RS02535	COG4703	Protein of unknown function (DUF1797)
NKZ63_RS02540	COG0765	amino acid transport
NKZ63_RS02550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NKZ63_RS02585	COG0789	Transcriptional regulator
NKZ63_RS02600	COG0826	peptidase U32
NKZ63_RS02610	COG4443	Transcriptional Coactivator p15 (PC4)
NKZ63_RS02615	COG1268	BioY protein
NKZ63_RS02625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NKZ63_RS02635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKZ63_RS02640	COG1136	(ABC) transporter
NKZ63_RS02645	COG0577	efflux transmembrane transporter activity
NKZ63_RS02665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NKZ63_RS02675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NKZ63_RS02685	COG3859	Proton-coupled thiamine transporter YuaJ
NKZ63_RS02705	COG0772	Belongs to the SEDS family
NKZ63_RS02710	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NKZ63_RS02725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NKZ63_RS02735	COG3093	addiction module antidote protein HigA
NKZ63_RS02745	COG0149	triose-phosphate isomerase activity
NKZ63_RS02760	COG1078	dGTPase activity
NKZ63_RS02805	COG2884	Cell division ATP-binding protein ftsE
NKZ63_RS02810	COG2177	Part of the ABC transporter FtsEX involved in
NKZ63_RS02835	COG1132	(ABC) transporter
NKZ63_RS02840	COG1132	(ABC) transporter
NKZ63_RS02845	COG0038	chloride channel
NKZ63_RS02850	COG0287	Prephenate dehydrogenase
NKZ63_RS02850	COG1605	Chorismate mutase
NKZ63_RS02860	COG0716	FMN binding
NKZ63_RS02865	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NKZ63_RS02880	COG0772	Belongs to the SEDS family
NKZ63_RS02885	COG0693	protein deglycase activity
NKZ63_RS02890	COG0187	DNA topoisomerase II activity
NKZ63_RS02895	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NKZ63_RS02900	COG0560	Phosphoserine phosphatase
NKZ63_RS02940	COG1011	Hydrolase
NKZ63_RS02950	COG2706	6-phosphogluconolactonase activity
NKZ63_RS02955	COG0628	permease
NKZ63_RS02965	COG3527	Alpha-acetolactate decarboxylase
NKZ63_RS02970	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NKZ63_RS02975	COG3711	transcriptional antiterminator
NKZ63_RS02980	COG1263	PTS System
NKZ63_RS02980	COG2190	(PTS) system
NKZ63_RS02980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NKZ63_RS03000	COG3842	ATPase activity
NKZ63_RS03035	COG0488	(ABC) transporter
NKZ63_RS03045	COG2226	methyltransferase
NKZ63_RS03050	COG3442	glutamine amidotransferase
NKZ63_RS03055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NKZ63_RS03070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NKZ63_RS03075	COG0488	(ABC) transporter
NKZ63_RS03100	COG1573	uracil-dna glycosylase
NKZ63_RS03110	COG1704	LemA family
NKZ63_RS03115	COG2268	Band 7 protein
NKZ63_RS03130	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NKZ63_RS03160	COG1518	maintenance of DNA repeat elements
NKZ63_RS03170	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NKZ63_RS03175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NKZ63_RS03185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NKZ63_RS03190	COG0813	purine-nucleoside phosphorylase activity
NKZ63_RS03195	COG0058	SHG alpha-glucan phosphorylase activity
NKZ63_RS03205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NKZ63_RS03230	COG0270	DNA (cytosine-5-)-methyltransferase activity
NKZ63_RS03440	COG1396	sequence-specific DNA binding
NKZ63_RS03475	COG0488	(ABC) transporter
NKZ63_RS03490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NKZ63_RS03555	COG3843	relaxase mobilization nuclease domain protein
NKZ63_RS03580	COG0577	efflux transmembrane transporter activity
NKZ63_RS03580	COG1136	(ABC) transporter
NKZ63_RS03620	COG0647	UMP catabolic process
NKZ63_RS03630	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NKZ63_RS03635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NKZ63_RS03640	COG3547	Transposase (IS116 IS110 IS902 family)
NKZ63_RS03645	COG1970	mechanosensitive ion channel activity
NKZ63_RS03650	COG0358	DNA primase activity
NKZ63_RS03655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKZ63_RS03660	COG2151	metal-sulfur cluster biosynthetic enzyme
NKZ63_RS03695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NKZ63_RS03705	COG1131	(ABC) transporter
NKZ63_RS03710	COG2188	Transcriptional regulator
NKZ63_RS03720	COG0205	6-phosphofructokinase activity
NKZ63_RS03725	COG0469	pyruvate kinase activity
NKZ63_RS03740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NKZ63_RS03745	COG2755	lipolytic protein G-D-S-L family
NKZ63_RS03745	COG0657	acetylesterase activity
NKZ63_RS03755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NKZ63_RS03760	COG0765	amino acid transport
NKZ63_RS03765	COG1126	abc transporter atp-binding protein
NKZ63_RS03770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NKZ63_RS03785	COG3684	Belongs to the aldolase LacD family
NKZ63_RS03800	COG4120	Belongs to the binding-protein-dependent transport system permease family
NKZ63_RS03805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NKZ63_RS03805	COG1116	anion transmembrane transporter activity
NKZ63_RS03815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NKZ63_RS03820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NKZ63_RS03825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NKZ63_RS03830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NKZ63_RS03840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKZ63_RS03840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKZ63_RS03865	COG4122	O-methyltransferase activity
NKZ63_RS03870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NKZ63_RS03880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NKZ63_RS03900	COG1476	TRANSCRIPTIONal
NKZ63_RS03935	COG1028	Short-chain dehydrogenase reductase Sdr
NKZ63_RS03960	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NKZ63_RS03965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NKZ63_RS03975	COG3716	PTS system mannose fructose sorbose family IID component
NKZ63_RS03995	COG1609	Transcriptional regulator
NKZ63_RS04000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKZ63_RS04010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKZ63_RS04015	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NKZ63_RS04020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NKZ63_RS04025	COG0372	Belongs to the citrate synthase family
NKZ63_RS04030	COG0538	isocitrate dehydrogenase activity
NKZ63_RS04040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NKZ63_RS04080	COG1196	nuclear chromosome segregation
NKZ63_RS04085	COG0561	phosphatase activity
NKZ63_RS04090	COG0561	phosphatase activity
NKZ63_RS04095	COG0552	protein localization to endoplasmic reticulum
NKZ63_RS04110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NKZ63_RS04115	COG3689	TIGRFAM TIGR03943 family protein
NKZ63_RS04120	COG0701	Predicted permease
NKZ63_RS04135	COG1597	lipid kinase activity
NKZ63_RS04145	COG0356	it plays a direct role in the translocation of protons across the membrane
NKZ63_RS04150	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NKZ63_RS04155	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKZ63_RS04160	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NKZ63_RS04165	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NKZ63_RS04170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NKZ63_RS04175	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NKZ63_RS04185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKZ63_RS04200	COG2211	Major facilitator Superfamily
NKZ63_RS04215	COG3250	beta-galactosidase activity
NKZ63_RS04225	COG0800	Aldolase
NKZ63_RS04235	COG1312	Catalyzes the dehydration of D-mannonate
NKZ63_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
NKZ63_RS04270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKZ63_RS04270	COG0072	phenylalanine-tRNA ligase activity
NKZ63_RS04295	COG1051	belongs to the nudix hydrolase family
NKZ63_RS04300	COG0302	gtp cyclohydrolase
NKZ63_RS04320	COG2610	gluconate transmembrane transporter activity
NKZ63_RS04325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKZ63_RS04340	COG1846	Transcriptional regulator
NKZ63_RS04345	COG3759	membrane
NKZ63_RS04380	COG2195	Cleaves the N-terminal amino acid of tripeptides
NKZ63_RS04385	COG0561	phosphatase activity
NKZ63_RS04425	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NKZ63_RS04430	COG0196	riboflavin kinase activity
NKZ63_RS04435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NKZ63_RS04440	COG1393	Belongs to the ArsC family
NKZ63_RS04445	COG4476	Belongs to the UPF0223 family
NKZ63_RS04450	COG0483	inositol monophosphate 1-phosphatase activity
NKZ63_RS04455	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NKZ63_RS04455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NKZ63_RS04465	COG0573	inorganic phosphate transmembrane transporter activity
NKZ63_RS04470	COG0581	inorganic phosphate transmembrane transporter activity
NKZ63_RS04475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NKZ63_RS04480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NKZ63_RS04485	COG0704	Plays a role in the regulation of phosphate uptake
NKZ63_RS04495	COG0745	RESPONSE REGULATOR receiver
NKZ63_RS04500	COG5002	protein histidine kinase activity
NKZ63_RS04510	COG0268	Binds directly to 16S ribosomal RNA
NKZ63_RS04515	COG1072	(Pantothenic acid kinase))
NKZ63_RS04520	COG2813	Specifically methylates the guanine in position
NKZ63_RS04525	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NKZ63_RS04540	COG1744	ABC transporter substrate-binding protein PnrA-like
NKZ63_RS04545	COG3845	ABC transporter
NKZ63_RS04550	COG4603	Belongs to the binding-protein-dependent transport system permease family
NKZ63_RS04555	COG1079	Belongs to the binding-protein-dependent transport system permease family
NKZ63_RS04565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NKZ63_RS04570	COG3842	ATPase activity
NKZ63_RS04575	COG1176	ABC-type spermidine putrescine transport system, permease component I
NKZ63_RS04580	COG1177	transmembrane transport
NKZ63_RS04590	COG0038	chloride channel
NKZ63_RS04605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NKZ63_RS04610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NKZ63_RS04625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NKZ63_RS04630	COG0336	Belongs to the RNA methyltransferase TrmD family
NKZ63_RS04635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NKZ63_RS04640	COG1349	DNA-binding transcription factor activity
NKZ63_RS04645	COG1105	Belongs to the carbohydrate kinase PfkB family
NKZ63_RS04650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NKZ63_RS04650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NKZ63_RS04650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NKZ63_RS04660	COG1307	EDD domain protein, DegV family
NKZ63_RS04665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NKZ63_RS04670	COG0617	tRNA 3'-terminal CCA addition
NKZ63_RS04675	COG0488	(ABC) transporter
NKZ63_RS04685	COG1940	carbohydrate kinase activity
NKZ63_RS04700	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NKZ63_RS04705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NKZ63_RS04710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NKZ63_RS04725	COG0481	GTPase activity
NKZ63_RS04750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NKZ63_RS04755	COG2890	protein-(glutamine-N5) methyltransferase activity
NKZ63_RS04760	COG0009	L-threonylcarbamoyladenylate synthase
NKZ63_RS04770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NKZ63_RS04780	COG0741	lytic transglycosylase activity
NKZ63_RS04785	COG4221	oxidoreductase activity
NKZ63_RS04810	COG1401	restriction endodeoxyribonuclease activity
NKZ63_RS04815	COG4268	DNA restriction-modification system
NKZ63_RS04820	COG4974	Belongs to the 'phage' integrase family
NKZ63_RS04890	COG2188	Transcriptional regulator
NKZ63_RS04895	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NKZ63_RS04900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NKZ63_RS04925	COG4974	Belongs to the 'phage' integrase family
NKZ63_RS04940	COG0745	RESPONSE REGULATOR receiver
NKZ63_RS04955	COG0577	efflux transmembrane transporter activity
NKZ63_RS04960	COG1136	(ABC) transporter
NKZ63_RS04985	COG2382	esterase
NKZ63_RS05005	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NKZ63_RS05020	COG0222	ribosome binding
NKZ63_RS05025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NKZ63_RS05035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NKZ63_RS05040	COG0758	DNA mediated transformation
NKZ63_RS05045	COG0110	maltose O-acetyltransferase activity
NKZ63_RS05050	COG1937	Protein conserved in bacteria
NKZ63_RS05060	COG0446	pyridine nucleotide-disulphide oxidoreductase
NKZ63_RS05070	COG1272	protein, Hemolysin III
NKZ63_RS05080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NKZ63_RS05085	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NKZ63_RS05105	COG1940	carbohydrate kinase activity
NKZ63_RS05120	COG0395	ABC-type sugar transport system, permease component
NKZ63_RS05125	COG1175	transmembrane transport
NKZ63_RS05145	COG1070	Carbohydrate kinase
NKZ63_RS05165	COG0737	Belongs to the 5'-nucleotidase family
NKZ63_RS05180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NKZ63_RS05185	COG0463	Glycosyl transferase, family 2
NKZ63_RS05200	COG0284	orotidine-5'-phosphate decarboxylase activity
NKZ63_RS05205	COG0167	dihydroorotate dehydrogenase activity
NKZ63_RS05220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NKZ63_RS05230	COG0297	glycogen (starch) synthase activity
NKZ63_RS05240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NKZ63_RS05245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NKZ63_RS05260	COG3583	domain protein
NKZ63_RS05290	COG1126	abc transporter atp-binding protein
NKZ63_RS05300	COG0488	(ABC) transporter
NKZ63_RS05305	COG2873	o-acetylhomoserine
NKZ63_RS05335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NKZ63_RS05335	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NKZ63_RS05345	COG3711	transcriptional antiterminator
NKZ63_RS05350	COG3684	Belongs to the aldolase LacD family
NKZ63_RS05355	COG1105	Belongs to the carbohydrate kinase PfkB family
NKZ63_RS05360	COG0698	ribose 5-phosphate isomerase
NKZ63_RS05365	COG0698	ribose 5-phosphate isomerase
NKZ63_RS05370	COG1349	DNA-binding transcription factor activity
NKZ63_RS05400	COG1396	sequence-specific DNA binding
NKZ63_RS05405	COG1194	a g-specific adenine glycosylase
NKZ63_RS05415	COG1132	(ABC) transporter
NKZ63_RS05420	COG1132	(ABC) transporter
NKZ63_RS05425	COG0280	phosphate acetyltransferase
NKZ63_RS05430	COG0564	pseudouridine synthase activity
NKZ63_RS05435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NKZ63_RS05440	COG2357	RelA SpoT domain protein
NKZ63_RS05445	COG4116	CYTH
NKZ63_RS05455	COG1104	cysteine desulfurase activity
NKZ63_RS05470	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NKZ63_RS05475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NKZ63_RS05485	COG3764	Sortase (surface protein transpeptidase)
NKZ63_RS05490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKZ63_RS05495	COG0039	L-malate dehydrogenase activity
NKZ63_RS05510	COG0083	homoserine kinase activity
NKZ63_RS05515	COG0460	homoserine dehydrogenase
NKZ63_RS05520	COG0726	polysaccharide deacetylase
NKZ63_RS05525	COG1132	(ABC) transporter
NKZ63_RS05540	COG0228	four-way junction DNA binding
NKZ63_RS05550	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NKZ63_RS05565	COG0505	Belongs to the CarA family
NKZ63_RS05570	COG0540	Belongs to the ATCase OTCase family
NKZ63_RS05575	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NKZ63_RS05585	COG2824	Alkylphosphonate utilization operon protein PhnA
NKZ63_RS05590	COG0564	pseudouridine synthase activity
NKZ63_RS05610	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NKZ63_RS05615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NKZ63_RS05620	COG1114	Component of the transport system for branched-chain amino acids
NKZ63_RS05625	COG0301	tRNA thio-modification
NKZ63_RS05630	COG1104	cysteine desulfurase activity
NKZ63_RS05655	COG0539	negative regulation of cytoplasmic translation
NKZ63_RS05675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NKZ63_RS05685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKZ63_RS05700	COG2184	nucleotidyltransferase activity
NKZ63_RS05710	COG0187	DNA topoisomerase II activity
NKZ63_RS05720	COG1074	ATP-dependent DNA helicase activity
NKZ63_RS05725	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NKZ63_RS05770	COG1131	(ABC) transporter
NKZ63_RS05800	COG1011	Hydrolase
NKZ63_RS05815	COG0210	DNA helicase
NKZ63_RS05830	COG1164	Oligoendopeptidase f
NKZ63_RS05845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NKZ63_RS05850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NKZ63_RS05875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NKZ63_RS05880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NKZ63_RS05885	COG1447	Phosphotransferase system cellobiose-specific component IIA
NKZ63_RS05895	COG1349	DNA-binding transcription factor activity
NKZ63_RS05900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NKZ63_RS05925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NKZ63_RS05935	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NKZ63_RS05945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NKZ63_RS05950	COG4684	Psort location CytoplasmicMembrane, score
NKZ63_RS05955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NKZ63_RS05975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NKZ63_RS06010	COG0531	amino acid
NKZ63_RS06020	COG0708	Exodeoxyribonuclease III
NKZ63_RS06030	COG1393	Belongs to the ArsC family
NKZ63_RS06035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NKZ63_RS06040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NKZ63_RS06050	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NKZ63_RS06060	COG4467	Involved in initiation control of chromosome replication
NKZ63_RS06065	COG0470	DNA polymerase III
NKZ63_RS06070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NKZ63_RS06075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NKZ63_RS06090	COG0517	IMP dehydrogenase activity
NKZ63_RS06100	COG2333	competence protein COMEC
NKZ63_RS06100	COG0658	competence protein
NKZ63_RS06105	COG1596	polysaccharide export
NKZ63_RS06105	COG1555	photosystem II stabilization
NKZ63_RS06110	COG0204	Acyl-transferase
NKZ63_RS06115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NKZ63_RS06120	COG1120	ATPase activity
NKZ63_RS06125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NKZ63_RS06130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKZ63_RS06135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKZ63_RS06140	COG0386	Belongs to the glutathione peroxidase family
NKZ63_RS06145	COG1187	pseudouridine synthase activity
NKZ63_RS06150	COG0435	Glutathione S-transferase
NKZ63_RS06160	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NKZ63_RS06165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKZ63_RS06170	COG1696	Membrane protein involved in D-alanine export
NKZ63_RS06215	COG0463	Glycosyl transferase, family 2
NKZ63_RS06230	COG0363	glucosamine-6-phosphate deaminase activity
NKZ63_RS06235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NKZ63_RS06240	COG1438	arginine binding
NKZ63_RS06255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NKZ63_RS06260	COG1288	antiporter activity
NKZ63_RS06265	COG0549	Belongs to the carbamate kinase family
NKZ63_RS06270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NKZ63_RS06275	COG0454	-acetyltransferase
NKZ63_RS06290	COG1481	regulation of sporulation
NKZ63_RS06295	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NKZ63_RS06300	COG1660	Displays ATPase and GTPase activities
NKZ63_RS06305	COG0251	oxidation-reduction process
NKZ63_RS06320	COG0436	Aminotransferase
NKZ63_RS06335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKZ63_RS06340	COG0562	UDP-galactopyranose mutase
NKZ63_RS06375	COG1131	(ABC) transporter
NKZ63_RS06395	COG3843	relaxase mobilization nuclease domain protein
NKZ63_RS06410	COG0613	PHP domain protein
NKZ63_RS06415	COG0542	response to heat
NKZ63_RS06420	COG1396	sequence-specific DNA binding
NKZ63_RS06450	COG1192	Involved in chromosome partitioning
NKZ63_RS06485	COG4443	Transcriptional Coactivator p15 (PC4)
NKZ63_RS06490	COG1475	DNA binding
NKZ63_RS06660	COG0270	DNA (cytosine-5-)-methyltransferase activity
NKZ63_RS06675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKZ63_RS06685	COG0077	Prephenate dehydratase
NKZ63_RS06690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NKZ63_RS06710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NKZ63_RS06755	COG1083	cytidylyl-transferase
NKZ63_RS06755	COG2755	lipolytic protein G-D-S-L family
NKZ63_RS06770	COG2089	acid synthase
NKZ63_RS06800	COG1216	Glycosyl transferase, family 2
NKZ63_RS06800	COG1442	glycosyl transferase family 8
NKZ63_RS06805	COG1216	Glycosyl transferase, family 2
NKZ63_RS06805	COG1442	glycosyl transferase family 8
NKZ63_RS06820	COG0438	transferase activity, transferring glycosyl groups
NKZ63_RS06835	COG4464	protein tyrosine phosphatase activity
NKZ63_RS06845	COG3944	biosynthesis protein
NKZ63_RS06855	COG3022	response to hydroperoxide
NKZ63_RS06860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NKZ63_RS06880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKZ63_RS06885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NKZ63_RS06890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NKZ63_RS06920	COG3679	Belongs to the UPF0342 family
NKZ63_RS06925	COG0287	Prephenate dehydrogenase
NKZ63_RS06930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NKZ63_RS06935	COG0710	3-dehydroquinate dehydratase activity
NKZ63_RS06940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NKZ63_RS06945	COG1368	sulfuric ester hydrolase activity
NKZ63_RS06960	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NKZ63_RS06970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NKZ63_RS07000	COG1216	Glycosyl transferase, family 2
NKZ63_RS07015	COG1216	Glycosyl transferase, family 2
NKZ63_RS07015	COG1442	glycosyl transferase family 8
NKZ63_RS07020	COG1442	glycosyl transferase family 8
NKZ63_RS07050	COG0463	Glycosyl transferase, family 2
NKZ63_RS07080	COG1091	dTDP-4-dehydrorhamnose reductase activity
NKZ63_RS07085	COG1088	dTDP-glucose 4,6-dehydratase activity
NKZ63_RS07100	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NKZ63_RS07110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NKZ63_RS07115	COG2384	SAM-dependent methyltransferase
NKZ63_RS07130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NKZ63_RS07150	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NKZ63_RS07150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NKZ63_RS07155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKZ63_RS07165	COG0300	oxidoreductase activity
NKZ63_RS07170	COG1234	tRNA 3'-trailer cleavage
NKZ63_RS07180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NKZ63_RS07185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NKZ63_RS07195	COG2807	transmembrane transport
NKZ63_RS07200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NKZ63_RS07210	COG1702	phosphate starvation-inducible protein PhoH
NKZ63_RS07215	COG4479	Belongs to the UPF0346 family
NKZ63_RS07230	COG2996	Protein conserved in bacteria
NKZ63_RS07235	COG0233	cytoplasmic translational termination
NKZ63_RS07240	COG0528	UMP kinase activity
NKZ63_RS07245	COG2244	polysaccharide biosynthetic process
NKZ63_RS07250	COG0625	glutathione transferase activity
NKZ63_RS07275	COG0346	lactoylglutathione lyase activity
NKZ63_RS07280	COG0697	spore germination
NKZ63_RS07280	COG1674	ftsk spoiiie
NKZ63_RS07285	COG1621	beta-fructofuranosidase activity
NKZ63_RS07290	COG1653	transport
NKZ63_RS07295	COG0395	ABC-type sugar transport system, permease component
NKZ63_RS07300	COG4209	transmembrane transport
NKZ63_RS07305	COG1609	Transcriptional regulator
NKZ63_RS07325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NKZ63_RS07335	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NKZ63_RS07340	COG3547	Transposase (IS116 IS110 IS902 family)
NKZ63_RS07350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NKZ63_RS07370	COG1181	Belongs to the D-alanine--D-alanine ligase family
NKZ63_RS07375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NKZ63_RS07380	COG0768	penicillin binding
NKZ63_RS07385	COG0488	(ABC) transporter
NKZ63_RS07390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NKZ63_RS07400	COG0745	RESPONSE REGULATOR receiver
NKZ63_RS07410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NKZ63_RS07415	COG0765	amino acid transport
NKZ63_RS07420	COG0765	amino acid transport
NKZ63_RS07425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NKZ63_RS07440	COG0438	transferase activity, transferring glycosyl groups
NKZ63_RS07455	COG1609	Transcriptional regulator
NKZ63_RS07470	COG3716	PTS system mannose fructose sorbose family IID component
NKZ63_RS07475	COG3715	PTS system
NKZ63_RS07480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NKZ63_RS07495	COG1070	Carbohydrate kinase
NKZ63_RS07500	COG2115	Belongs to the xylose isomerase family
NKZ63_RS07510	COG1940	carbohydrate kinase activity
NKZ63_RS07525	COG0343	queuine tRNA-ribosyltransferase activity
NKZ63_RS07535	COG1832	CoA-binding protein
NKZ63_RS07545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NKZ63_RS07545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NKZ63_RS07555	COG3547	Transposase (IS116 IS110 IS902 family)
NKZ63_RS07565	COG1136	(ABC) transporter
NKZ63_RS07575	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NKZ63_RS07580	COG2217	Heavy metal translocating P-type atpase
NKZ63_RS07595	COG1063	alcohol dehydrogenase
NKZ63_RS07600	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NKZ63_RS07605	COG0557	exoribonuclease II activity
NKZ63_RS07615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NKZ63_RS07620	COG2814	Major facilitator Superfamily
NKZ63_RS07630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NKZ63_RS07635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NKZ63_RS07640	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NKZ63_RS07650	COG1737	Transcriptional regulator
NKZ63_RS07660	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NKZ63_RS07670	COG1011	Hydrolase
NKZ63_RS07905	COG3561	AntA/AntB antirepressor
NKZ63_RS07960	COG0737	Belongs to the 5'-nucleotidase family
NKZ63_RS07970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NKZ63_RS07975	COG1466	dna polymerase III delta subunit
NKZ63_RS08010	COG0683	leucine binding
NKZ63_RS08025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NKZ63_RS08030	COG0366	Alpha amylase catalytic
NKZ63_RS08040	COG0395	ABC-type sugar transport system, permease component
NKZ63_RS08045	COG1175	transmembrane transport
NKZ63_RS08050	COG1653	transport
NKZ63_RS08065	COG1653	transport
NKZ63_RS08075	COG2207	Transcriptional regulator
NKZ63_RS08080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NKZ63_RS08085	COG0626	cystathionine gamma-synthase activity
NKZ63_RS08105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NKZ63_RS08110	COG2827	Endonuclease containing a URI domain
NKZ63_RS08130	COG0640	Transcriptional regulator
NKZ63_RS08135	COG0513	Belongs to the DEAD box helicase family
NKZ63_RS08140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NKZ63_RS08180	COG0494	nUDIX hydrolase
NKZ63_RS08185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NKZ63_RS08195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NKZ63_RS08200	COG1028	Short-chain dehydrogenase reductase Sdr
NKZ63_RS08210	COG0582	viral genome integration into host DNA
NKZ63_RS08320	COG0577	efflux transmembrane transporter activity
NKZ63_RS08325	COG1136	(ABC) transporter
NKZ63_RS08330	COG2205	protein histidine kinase activity
NKZ63_RS08345	COG0436	Aminotransferase
NKZ63_RS08355	COG1174	glycine betaine transport
NKZ63_RS08360	COG0517	IMP dehydrogenase activity
NKZ63_RS08360	COG1125	glycine betaine transport
NKZ63_RS08380	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NKZ63_RS08385	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NKZ63_RS08390	COG1482	cell wall glycoprotein biosynthetic process
NKZ63_RS08405	COG3091	SprT-like family
NKZ63_RS08410	COG2183	response to ionizing radiation
NKZ63_RS08430	COG0656	L-ascorbic acid biosynthetic process
NKZ63_RS08435	COG4708	membrane
NKZ63_RS08440	COG2246	polysaccharide biosynthetic process
NKZ63_RS08450	COG0024	Methionine aminopeptidase
NKZ63_RS08460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKZ63_RS08465	COG2249	NAD(P)H dehydrogenase (quinone) activity
NKZ63_RS08470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NKZ63_RS08475	COG2131	deaminase
NKZ63_RS08485	COG1363	Peptidase, m42
NKZ63_RS08500	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKZ63_RS08505	COG1956	GAF domain-containing protein
NKZ63_RS08525	COG0673	inositol 2-dehydrogenase activity
NKZ63_RS08530	COG0513	Belongs to the DEAD box helicase family
NKZ63_RS08535	COG0726	polysaccharide deacetylase
NKZ63_RS08550	COG0183	Belongs to the thiolase family
NKZ63_RS08555	COG3425	synthase
NKZ63_RS08570	COG0776	regulation of translation
NKZ63_RS08580	COG2755	lipolytic protein G-D-S-L family
NKZ63_RS08585	COG1307	EDD domain protein, DegV family
NKZ63_RS08590	COG0497	DNA recombination
NKZ63_RS08595	COG1438	arginine binding
NKZ63_RS08600	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NKZ63_RS08610	COG1722	exodeoxyribonuclease VII activity
NKZ63_RS08615	COG1570	exodeoxyribonuclease VII activity
NKZ63_RS08620	COG2321	neutral zinc metallopeptidase
NKZ63_RS08625	COG1755	Isoprenylcysteine carboxyl methyltransferase
NKZ63_RS08630	COG5002	protein histidine kinase activity
NKZ63_RS08635	COG0745	RESPONSE REGULATOR receiver
NKZ63_RS08725	COG0582	viral genome integration into host DNA
NKZ63_RS08735	COG1227	inorganic diphosphatase activity
NKZ63_RS08745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NKZ63_RS08750	COG1253	flavin adenine dinucleotide binding
NKZ63_RS08755	COG1119	ATPase activity
NKZ63_RS08760	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NKZ63_RS08780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NKZ63_RS08785	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NKZ63_RS08790	COG0133	tryptophan synthase activity
NKZ63_RS08805	COG4470	Protein conserved in bacteria
NKZ63_RS08810	COG3480	Lon protease (S16) C-terminal proteolytic domain
NKZ63_RS08815	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NKZ63_RS08820	COG0742	ribosomal rna small subunit methyltransferase
NKZ63_RS08830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NKZ63_RS08835	COG4483	Protein conserved in bacteria
NKZ63_RS08840	COG2197	response regulator
NKZ63_RS08845	COG2203	Gaf domain
NKZ63_RS08845	COG4585	Histidine kinase
NKZ63_RS08850	COG0842	Transport permease protein
NKZ63_RS08855	COG1131	(ABC) transporter
NKZ63_RS08870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NKZ63_RS08880	COG2755	lipolytic protein G-D-S-L family
NKZ63_RS08880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NKZ63_RS08885	COG0671	phosphoesterase, PA-phosphatase related
NKZ63_RS08890	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NKZ63_RS08900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NKZ63_RS08905	COG1187	pseudouridine synthase activity
NKZ63_RS08910	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NKZ63_RS08915	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NKZ63_RS08920	COG0582	viral genome integration into host DNA
NKZ63_RS08940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NKZ63_RS08945	COG3763	UPF0154 protein
NKZ63_RS08955	COG3579	cysteine-type endopeptidase activity
NKZ63_RS08970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKZ63_RS08975	COG1254	Belongs to the acylphosphatase family
NKZ63_RS08985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NKZ63_RS08990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NKZ63_RS09000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NKZ63_RS09010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NKZ63_RS09025	COG1160	GTP binding
NKZ63_RS09035	COG1484	DNA-dependent DNA replication
NKZ63_RS09045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NKZ63_RS09050	COG0628	permease
NKZ63_RS09055	COG0745	RESPONSE REGULATOR receiver
NKZ63_RS09060	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NKZ63_RS09070	COG0492	ferredoxin-NADP+ reductase activity
NKZ63_RS09080	COG0513	Belongs to the DEAD box helicase family
NKZ63_RS09085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NKZ63_RS09090	COG0768	penicillin binding
NKZ63_RS09100	COG0275	rRNA processing
NKZ63_RS09145	COG4939	FMN-binding domain protein
NKZ63_RS09150	COG0142	geranyltranstransferase activity
NKZ63_RS09155	COG1252	NADH dehydrogenase
NKZ63_RS09165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NKZ63_RS09170	COG0569	domain protein
NKZ63_RS09175	COG0534	Mate efflux family protein
NKZ63_RS09185	COG4224	UPF0291 protein
NKZ63_RS09190	COG0751	glycine-tRNA ligase activity
NKZ63_RS09215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NKZ63_RS09220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NKZ63_RS09225	COG1464	Belongs to the NlpA lipoprotein family
NKZ63_RS09230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NKZ63_RS09235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NKZ63_RS09240	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NKZ63_RS09245	COG2252	PERMEase
NKZ63_RS09250	COG0561	phosphatase activity
NKZ63_RS09265	COG3715	PTS system
NKZ63_RS09270	COG3716	PTS system mannose fructose sorbose family IID component
NKZ63_RS09295	COG3177	Filamentation induced by cAMP protein fic
NKZ63_RS09305	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NKZ63_RS09345	COG0439	Biotin carboxylase
NKZ63_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
NKZ63_RS09370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NKZ63_RS09375	COG2070	2-Nitropropane dioxygenase
NKZ63_RS09385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NKZ63_RS09395	COG1024	Enoyl-CoA hydratase
NKZ63_RS09400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NKZ63_RS09405	COG0527	aspartate kinase activity
NKZ63_RS09410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NKZ63_RS09415	COG0736	holo-[acyl-carrier-protein] synthase activity
NKZ63_RS09420	COG0653	protein targeting
NKZ63_RS09430	COG1940	carbohydrate kinase activity
NKZ63_RS09435	COG1263	PTS System
NKZ63_RS09435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NKZ63_RS09435	COG2190	(PTS) system
NKZ63_RS09440	COG1621	beta-fructofuranosidase activity
NKZ63_RS09445	COG1609	Transcriptional regulator
NKZ63_RS09450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NKZ63_RS09465	COG0006	proline dipeptidase activity
NKZ63_RS09470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NKZ63_RS09485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NKZ63_RS09490	COG0629	single-stranded DNA binding
NKZ63_RS09500	COG0095	Lipoate-protein ligase
NKZ63_RS09505	COG2723	6-phospho-beta-galactosidase activity
NKZ63_RS09520	COG2723	6-phospho-beta-galactosidase activity
NKZ63_RS09525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NKZ63_RS09535	COG1447	Phosphotransferase system cellobiose-specific component IIA
NKZ63_RS09540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NKZ63_RS09540	COG3711	transcriptional antiterminator
NKZ63_RS09555	COG4095	Psort location CytoplasmicMembrane, score
NKZ63_RS09560	COG2723	6-phospho-beta-galactosidase activity
NKZ63_RS09565	COG0346	lactoylglutathione lyase activity
NKZ63_RS09570	COG2723	6-phospho-beta-galactosidase activity
NKZ63_RS09575	COG2207	Transcriptional regulator
NKZ63_RS09575	COG1917	Cupin 2, conserved barrel domain protein
NKZ63_RS09585	COG1263	PTS System
NKZ63_RS09585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NKZ63_RS09585	COG2190	(PTS) system
NKZ63_RS09590	COG3711	transcriptional antiterminator
NKZ63_RS09605	COG0508	dehydrogenase complex catalyzes the overall conversion of
NKZ63_RS09610	COG0022	dehydrogenase e1 component
NKZ63_RS09610	COG0508	dehydrogenase complex catalyzes the overall conversion of
NKZ63_RS09615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NKZ63_RS09620	COG2860	membrane
NKZ63_RS09635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NKZ63_RS09640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NKZ63_RS09650	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NKZ63_RS09655	COG0195	Participates in both transcription termination and antitermination
NKZ63_RS09665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NKZ63_RS09675	COG4473	ABC transporter
NKZ63_RS09680	COG1131	(ABC) transporter
NKZ63_RS09685	COG0537	adenosine 5'-monophosphoramidase activity
NKZ63_RS09695	COG1316	TRANSCRIPTIONal
NKZ63_RS09705	COG0802	atpase or kinase
NKZ63_RS09710	COG1461	Dihydroxyacetone kinase
NKZ63_RS09725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKZ63_RS09730	COG0601	transmembrane transport
NKZ63_RS09735	COG4608	Belongs to the ABC transporter superfamily
NKZ63_RS09745	COG0747	negative chemotaxis
NKZ63_RS09755	COG1686	Belongs to the peptidase S11 family
NKZ63_RS09770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NKZ63_RS09775	COG0719	Fe-S assembly protein
NKZ63_RS09785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NKZ63_RS09790	COG4862	establishment of competence for transformation
NKZ63_RS09795	COG1968	undecaprenyl-diphosphatase activity
NKZ63_RS09800	COG0765	amino acid transport
NKZ63_RS09820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NKZ63_RS09825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NKZ63_RS09830	COG0440	acetolactate synthase activity
NKZ63_RS09835	COG0028	Belongs to the TPP enzyme family
NKZ63_RS09840	COG0463	Glycosyl transferase, family 2
NKZ63_RS09855	COG0129	dihydroxy-acid dehydratase activity
NKZ63_RS09865	COG2151	metal-sulfur cluster biosynthetic enzyme
NKZ63_RS09915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NKZ63_RS09935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKZ63_RS09950	COG3842	ATPase activity
NKZ63_RS09960	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NKZ63_RS09980	COG1045	serine acetyltransferase
NKZ63_RS09985	COG1185	polyribonucleotide nucleotidyltransferase activity
NKZ63_RS10000	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NKZ63_RS10005	COG1131	(ABC) transporter
NKZ63_RS10040	COG1187	pseudouridine synthase activity
NKZ63_RS10055	COG0242	peptide deformylase activity
NKZ63_RS10065	COG0066	3-isopropylmalate dehydratase activity
NKZ63_RS10085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NKZ63_RS10100	COG1447	Phosphotransferase system cellobiose-specific component IIA
NKZ63_RS10115	COG2309	aminopeptidase activity
NKZ63_RS10130	COG2176	DNA-directed DNA polymerase activity
NKZ63_RS10135	COG2376	Dihydroxyacetone kinase
NKZ63_RS10145	COG2376	Dihydroxyacetone kinase
NKZ63_RS10150	COG1461	Dihydroxyacetone kinase
NKZ63_RS10155	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NKZ63_RS10160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NKZ63_RS10165	COG0442	prolyl-tRNA aminoacylation
NKZ63_RS10175	COG4589	Belongs to the CDS family
NKZ63_RS10180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NKZ63_RS10185	COG1862	Preprotein translocase
NKZ63_RS10195	COG2918	glutathione biosynthetic process
NKZ63_RS10195	COG1181	Belongs to the D-alanine--D-alanine ligase family
NKZ63_RS10205	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NKZ63_RS10210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NKZ63_RS10215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NKZ63_RS10220	COG0542	response to heat
NKZ63_RS10225	COG4463	regulation of RNA biosynthetic process
NKZ63_RS10245	COG1388	LysM domain
NKZ63_RS10245	COG4932	domain protein
NKZ63_RS10250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NKZ63_RS10285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NKZ63_RS10290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NKZ63_RS10295	COG0492	ferredoxin-NADP+ reductase activity
NKZ63_RS10300	COG0564	pseudouridine synthase activity
NKZ63_RS10305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NKZ63_RS10325	COG1564	THIamine pyrophosphokinase
NKZ63_RS10335	COG1162	GTPase activity
NKZ63_RS10345	COG3547	Transposase (IS116 IS110 IS902 family)
NKZ63_RS10355	COG3547	Transposase (IS116 IS110 IS902 family)
NKZ63_RS10380	COG4115	mRNA cleavage
NKZ63_RS10405	COG0084	hydrolase, TatD family'
NKZ63_RS10415	COG1847	R3H domain protein
NKZ63_RS10425	COG0594	ribonuclease P activity
NKZ63_RS10430	COG0165	Argininosuccinate lyase
NKZ63_RS10435	COG0137	argininosuccinate synthase activity
NKZ63_RS10445	COG1827	regulation of RNA biosynthetic process
NKZ63_RS10515	COG0756	dUTP diphosphatase activity
NKZ63_RS10520	COG1132	(ABC) transporter
NKZ63_RS10525	COG1132	(ABC) transporter
NKZ63_RS10535	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NKZ63_RS10540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NKZ63_RS10545	COG0705	Rhomboid family
NKZ63_RS10550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NKZ63_RS10555	COG1473	amidohydrolase
NKZ63_RS10560	COG2171	N-acyltransferase activity
NKZ63_RS10570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NKZ63_RS10595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NKZ63_RS10620	COG3623	hexulose-6-phosphate isomerase
NKZ63_RS10645	COG1523	belongs to the glycosyl hydrolase 13 family
NKZ63_RS10650	COG1609	Transcriptional regulator
NKZ63_RS10655	COG1126	abc transporter atp-binding protein
NKZ63_RS10660	COG0765	amino acid transport
NKZ63_RS10665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NKZ63_RS10670	COG3942	CHAP domain
NKZ63_RS10675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NKZ63_RS10685	COG1447	Phosphotransferase system cellobiose-specific component IIA
NKZ63_RS10695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NKZ63_RS10695	COG3711	transcriptional antiterminator
NKZ63_RS10705	COG2723	6-phospho-beta-galactosidase activity
NKZ63_RS10710	COG1486	melibiose metabolic process
NKZ63_RS10720	COG3590	peptidase
NKZ63_RS10725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NKZ63_RS10730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NKZ63_RS10730	COG1321	iron dependent repressor
NKZ63_RS10735	COG1121	(ABC) transporter
NKZ63_RS10745	COG0803	Belongs to the bacterial solute-binding protein 9 family
NKZ63_RS10765	COG1490	D-aminoacyl-tRNA deacylase activity
NKZ63_RS10775	COG0737	Belongs to the 5'-nucleotidase family
NKZ63_RS10795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NKZ63_RS10820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NKZ63_RS10845	COG0737	Belongs to the 5'-nucleotidase family
NKZ63_RS10850	COG1328	CTP reductase activity
NKZ63_RS10855	COG1126	abc transporter atp-binding protein
NKZ63_RS10865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NKZ63_RS10890	COG1438	arginine binding
NKZ63_RS10895	COG0018	arginyl-trna synthetase
NKZ63_RS10915	COG1640	4-alpha-glucanotransferase
NKZ63_RS10925	COG2182	Extracellular solute-binding protein
NKZ63_RS10930	COG1175	transmembrane transport
NKZ63_RS10935	COG3833	ABC-type maltose transport systems, permease component
NKZ63_RS10940	COG5521	maltodextrose utilization protein MalA
NKZ63_RS10945	COG1609	Transcriptional regulator
NKZ63_RS10950	COG1523	belongs to the glycosyl hydrolase 13 family
NKZ63_RS10955	COG1780	Probably involved in ribonucleotide reductase function
NKZ63_RS10960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NKZ63_RS10965	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NKZ63_RS10970	COG2153	protein acetylation
NKZ63_RS10975	COG4989	oxidoreductase activity
NKZ63_RS10980	COG1216	Glycosyl transferase, family 2
NKZ63_RS11000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NKZ63_RS11010	COG0305	Participates in initiation and elongation during chromosome replication
NKZ63_RS11015	COG0359	binds to the 23S rRNA
NKZ63_RS11025	COG0445	tRNA wobble uridine modification
NKZ63_RS11030	COG0494	nUDIX hydrolase
NKZ63_RS11035	COG1733	regulation of RNA biosynthetic process
NKZ63_RS11045	COG0482	sulfurtransferase activity
NKZ63_RS11050	COG1760	l-serine dehydratase
NKZ63_RS11055	COG1760	l-serine dehydratase
NKZ63_RS11065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKZ63_RS11070	COG1122	ATPase activity
NKZ63_RS11075	COG1122	ATPase activity
NKZ63_RS11080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKZ63_RS11085	COG1426	Protein conserved in bacteria
NKZ63_RS11090	COG0612	Peptidase, M16
NKZ63_RS11095	COG0612	Peptidase, M16
NKZ63_RS11185	COG0582	viral genome integration into host DNA
NKZ63_RS11195	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NKZ63_RS11200	COG0516	GMP reductase activity
NKZ63_RS11200	COG0517	IMP dehydrogenase activity
NKZ63_RS11210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NKZ63_RS11215	COG0488	(ABC) transporter
NKZ63_RS11245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NKZ63_RS11250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKZ63_RS11255	COG1475	DNA binding