locus-tag	class	description
STACADC2_RS00010	COG0592	DNA-directed DNA polymerase activity
STACADC2_RS00020	COG0012	GTP binding
STACADC2_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
STACADC2_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
STACADC2_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STACADC2_RS00195	COG3942	CHAP domain
STACADC2_RS00210	COG0436	Aminotransferase
STACADC2_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STACADC2_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
STACADC2_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
STACADC2_RS00270	COG0151	Belongs to the GarS family
STACADC2_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STACADC2_RS00295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STACADC2_RS00310	COG4550	Control of competence regulator ComK, YlbF/YmcA
STACADC2_RS00360	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
STACADC2_RS00365	COG1393	Belongs to the ArsC family
STACADC2_RS00455	COG2309	aminopeptidase activity
STACADC2_RS00470	COG0431	NADPH-dependent FMN reductase
STACADC2_RS00515	COG4463	regulation of RNA biosynthetic process
STACADC2_RS00520	COG0542	response to heat
STACADC2_RS00525	COG1686	Belongs to the peptidase S11 family
STACADC2_RS00535	COG1686	Belongs to the peptidase S11 family
STACADC2_RS00550	COG1045	serine acetyltransferase
STACADC2_RS00560	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
STACADC2_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STACADC2_RS00605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
STACADC2_RS00675	COG3830	Belongs to the UPF0237 family
STACADC2_RS00685	COG0588	phosphoglycerate mutase activity
STACADC2_RS00690	COG1876	peptidase activity
STACADC2_RS00725	COG0351	phosphomethylpyrimidine kinase
STACADC2_RS00765	COG1473	amidohydrolase
STACADC2_RS00770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
STACADC2_RS00790	COG0668	transmembrane transport
STACADC2_RS00805	COG0504	CTP synthase activity
STACADC2_RS00815	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
STACADC2_RS00825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
STACADC2_RS00865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
STACADC2_RS00900	COG1126	abc transporter atp-binding protein
STACADC2_RS00905	COG0765	amino acid transport
STACADC2_RS00910	COG1968	undecaprenyl-diphosphatase activity
STACADC2_RS00925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STACADC2_RS00935	COG0719	Fe-S assembly protein
STACADC2_RS00940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
STACADC2_RS00950	COG0719	Fe-S assembly protein
STACADC2_RS00955	COG4166	transmembrane transport
STACADC2_RS00960	COG0601	transmembrane transport
STACADC2_RS00970	COG0444	Belongs to the ABC transporter superfamily
STACADC2_RS00980	COG4608	Belongs to the ABC transporter superfamily
STACADC2_RS00995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
STACADC2_RS01020	COG1121	(ABC) transporter
STACADC2_RS01025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STACADC2_RS01035	COG2190	(PTS) system
STACADC2_RS01035	COG1263	PTS System
STACADC2_RS01035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STACADC2_RS01040	COG1263	PTS System
STACADC2_RS01040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STACADC2_RS01040	COG2190	(PTS) system
STACADC2_RS01045	COG1263	PTS System
STACADC2_RS01045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STACADC2_RS01045	COG2190	(PTS) system
STACADC2_RS01050	COG1263	PTS System
STACADC2_RS01050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STACADC2_RS01050	COG2190	(PTS) system
STACADC2_RS01080	COG4589	Belongs to the CDS family
STACADC2_RS01095	COG4120	Belongs to the binding-protein-dependent transport system permease family
STACADC2_RS01100	COG1116	anion transmembrane transporter activity
STACADC2_RS01100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
STACADC2_RS01135	COG0564	pseudouridine synthase activity
STACADC2_RS01140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STACADC2_RS01170	COG1349	DNA-binding transcription factor activity
STACADC2_RS01200	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
STACADC2_RS01215	COG3579	cysteine-type endopeptidase activity
STACADC2_RS01220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STACADC2_RS01245	COG0116	Belongs to the methyltransferase superfamily
STACADC2_RS01255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
STACADC2_RS01275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
STACADC2_RS01295	COG1254	Belongs to the acylphosphatase family
STACADC2_RS01300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STACADC2_RS01365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
STACADC2_RS01370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
STACADC2_RS01375	COG1187	pseudouridine synthase activity
STACADC2_RS01385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STACADC2_RS01390	COG0569	domain protein
STACADC2_RS01400	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
STACADC2_RS01405	COG0671	phosphoesterase, PA-phosphatase related
STACADC2_RS01425	COG2274	protein secretion by the type I secretion system
STACADC2_RS01430	COG2274	protein secretion by the type I secretion system
STACADC2_RS01485	COG0829	nickel cation binding
STACADC2_RS01490	COG0310	cobalt ion transport
STACADC2_RS01500	COG1122	ATPase activity
STACADC2_RS01505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STACADC2_RS01510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
STACADC2_RS01530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STACADC2_RS01535	COG1464	Belongs to the NlpA lipoprotein family
STACADC2_RS01545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
STACADC2_RS01555	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
STACADC2_RS01580	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
STACADC2_RS01595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STACADC2_RS01610	COG0745	RESPONSE REGULATOR receiver
STACADC2_RS01615	COG5002	protein histidine kinase activity
STACADC2_RS01630	COG1484	DNA-dependent DNA replication
STACADC2_RS01650	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
STACADC2_RS01660	COG3328	transposase activity
STACADC2_RS01675	COG3716	PTS system mannose fructose sorbose family IID component
STACADC2_RS01680	COG3715	PTS system
STACADC2_RS01690	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
STACADC2_RS01695	COG0561	phosphatase activity
STACADC2_RS01700	COG2252	PERMEase
STACADC2_RS01705	COG0802	atpase or kinase
STACADC2_RS01710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STACADC2_RS01715	COG1316	TRANSCRIPTIONal
STACADC2_RS01725	COG0195	Participates in both transcription termination and antitermination
STACADC2_RS01730	COG2740	Nucleic-acid-binding protein implicated in transcription termination
STACADC2_RS01740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
STACADC2_RS01750	COG1611	Belongs to the LOG family
STACADC2_RS01770	COG2244	polysaccharide biosynthetic process
STACADC2_RS01780	COG0626	cystathionine gamma-synthase activity
STACADC2_RS01785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
STACADC2_RS01815	COG4471	UPF0298 protein
STACADC2_RS01825	COG0559	Belongs to the binding-protein-dependent transport system permease family
STACADC2_RS01855	COG1739	Uncharacterized protein family UPF0029
STACADC2_RS01860	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
STACADC2_RS01865	COG1040	competence protein
STACADC2_RS01955	COG0527	aspartate kinase activity
STACADC2_RS01960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STACADC2_RS01965	COG1024	Enoyl-CoA hydratase
STACADC2_RS01970	COG1846	Transcriptional regulator
STACADC2_RS01990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
STACADC2_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
STACADC2_RS02000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STACADC2_RS02015	COG0439	Biotin carboxylase
STACADC2_RS02045	COG0076	glutamate decarboxylase activity
STACADC2_RS02050	COG0531	amino acid
STACADC2_RS02080	COG1349	DNA-binding transcription factor activity
STACADC2_RS02085	COG1105	Belongs to the carbohydrate kinase PfkB family
STACADC2_RS02095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STACADC2_RS02100	COG0285	dihydrofolate synthase activity
STACADC2_RS02110	COG1104	cysteine desulfurase activity
STACADC2_RS02175	COG0488	(ABC) transporter
STACADC2_RS02195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STACADC2_RS02200	COG0242	peptide deformylase activity
STACADC2_RS02250	COG3942	CHAP domain
STACADC2_RS02260	COG1702	phosphate starvation-inducible protein PhoH
STACADC2_RS02280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STACADC2_RS02280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STACADC2_RS02305	COG4122	O-methyltransferase activity
STACADC2_RS02310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
STACADC2_RS02335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STACADC2_RS02340	COG0436	Aminotransferase
STACADC2_RS02350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
STACADC2_RS02355	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
STACADC2_RS02360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
STACADC2_RS02365	COG0726	polysaccharide deacetylase
STACADC2_RS02380	COG2962	Rard protein
STACADC2_RS02420	COG0356	it plays a direct role in the translocation of protons across the membrane
STACADC2_RS02455	COG0772	Belongs to the SEDS family
STACADC2_RS02475	COG0470	DNA polymerase III
STACADC2_RS02480	COG1774	PSP1 C-terminal conserved region
STACADC2_RS02485	COG4467	Involved in initiation control of chromosome replication
STACADC2_RS02495	COG0004	ammonium transporteR
STACADC2_RS02500	COG0347	Belongs to the P(II) protein family
STACADC2_RS02505	COG1705	Flagellar rod assembly protein muramidase FlgJ
STACADC2_RS02505	COG1388	LysM domain
STACADC2_RS02555	COG1113	amino acid transport
STACADC2_RS02595	COG0583	DNA-binding transcription factor activity
STACADC2_RS02605	COG0564	pseudouridine synthase activity
STACADC2_RS02625	COG0505	Belongs to the CarA family
STACADC2_RS02690	COG3279	Response regulator of the LytR AlgR family
STACADC2_RS02700	COG1131	(ABC) transporter
STACADC2_RS02735	COG1187	pseudouridine synthase activity
STACADC2_RS02740	COG1473	amidohydrolase
STACADC2_RS02745	COG0686	Belongs to the AlaDH PNT family
STACADC2_RS02750	COG0686	Belongs to the AlaDH PNT family
STACADC2_RS02755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STACADC2_RS02815	COG0438	transferase activity, transferring glycosyl groups
STACADC2_RS02850	COG1272	protein, Hemolysin III
STACADC2_RS02870	COG3425	synthase
STACADC2_RS02880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
STACADC2_RS02900	COG0833	amino acid
STACADC2_RS02905	COG2040	homocysteine
STACADC2_RS02925	COG0187	DNA topoisomerase II activity
STACADC2_RS02935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STACADC2_RS02955	COG0539	negative regulation of cytoplasmic translation
STACADC2_RS03005	COG0494	nUDIX hydrolase
STACADC2_RS03010	COG0542	response to heat
STACADC2_RS03015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
STACADC2_RS03020	COG4703	Protein of unknown function (DUF1797)
STACADC2_RS03025	COG0765	amino acid transport
STACADC2_RS03080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STACADC2_RS03085	COG0768	penicillin binding
STACADC2_RS03090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
STACADC2_RS03105	COG3711	transcriptional antiterminator
STACADC2_RS03115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
STACADC2_RS03120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
STACADC2_RS03125	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
STACADC2_RS03130	COG0237	dephospho-CoA kinase activity
STACADC2_RS03135	COG2814	Major facilitator Superfamily
STACADC2_RS03150	COG0557	exoribonuclease II activity
STACADC2_RS03165	COG1185	polyribonucleotide nucleotidyltransferase activity
STACADC2_RS03170	COG0006	proline dipeptidase activity
STACADC2_RS03175	COG1609	Transcriptional regulator
STACADC2_RS03210	COG1368	sulfuric ester hydrolase activity
STACADC2_RS03215	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
STACADC2_RS03240	COG0287	Prephenate dehydrogenase
STACADC2_RS03255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
STACADC2_RS03265	COG0077	Prephenate dehydratase
STACADC2_RS03325	COG1518	maintenance of DNA repeat elements
STACADC2_RS03330	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STACADC2_RS03340	COG3689	TIGRFAM TIGR03943 family protein
STACADC2_RS03345	COG0701	Predicted permease
STACADC2_RS03350	COG2183	response to ionizing radiation
STACADC2_RS03370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
STACADC2_RS03395	COG0826	peptidase U32
STACADC2_RS03405	COG1268	BioY protein
STACADC2_RS03415	COG4443	Transcriptional Coactivator p15 (PC4)
STACADC2_RS03420	COG1914	H( )-stimulated, divalent metal cation uptake system
STACADC2_RS03430	COG0494	nUDIX hydrolase
STACADC2_RS03465	COG0406	alpha-ribazole phosphatase activity
STACADC2_RS03470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
STACADC2_RS03515	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STACADC2_RS03540	COG3620	sequence-specific DNA binding
STACADC2_RS03555	COG1704	LemA family
STACADC2_RS03560	COG0501	Belongs to the peptidase M48B family
STACADC2_RS03575	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
STACADC2_RS03585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
STACADC2_RS03595	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
STACADC2_RS03600	COG0783	Belongs to the Dps family
STACADC2_RS03605	COG0735	belongs to the Fur family
STACADC2_RS03610	COG4483	Protein conserved in bacteria
STACADC2_RS03615	COG1940	carbohydrate kinase activity
STACADC2_RS03620	COG1217	gtp-binding protein TYPA
STACADC2_RS03645	COG0849	cell division
STACADC2_RS03655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STACADC2_RS03675	COG3599	regulation of cell shape
STACADC2_RS03680	COG3599	regulation of cell shape
STACADC2_RS03710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STACADC2_RS03715	COG0625	glutathione transferase activity
STACADC2_RS03720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
STACADC2_RS03725	COG1435	thymidine kinase activity
STACADC2_RS03735	COG2890	protein-(glutamine-N5) methyltransferase activity
STACADC2_RS03745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
STACADC2_RS03765	COG1132	(ABC) transporter
STACADC2_RS03780	COG1696	Membrane protein involved in D-alanine export
STACADC2_RS03790	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
STACADC2_RS03800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STACADC2_RS03805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STACADC2_RS03825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STACADC2_RS03830	COG4684	Psort location CytoplasmicMembrane, score
STACADC2_RS03835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STACADC2_RS03860	COG5002	protein histidine kinase activity
STACADC2_RS03885	COG2813	Specifically methylates the guanine in position
STACADC2_RS03905	COG0295	cytidine deaminase activity
STACADC2_RS03910	COG1744	ABC transporter substrate-binding protein PnrA-like
STACADC2_RS03915	COG3845	ABC transporter
STACADC2_RS03920	COG4603	Belongs to the binding-protein-dependent transport system permease family
STACADC2_RS03925	COG1079	Belongs to the binding-protein-dependent transport system permease family
STACADC2_RS03935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
STACADC2_RS03935	COG1199	ATP-dependent helicase activity
STACADC2_RS03945	COG0436	Aminotransferase
STACADC2_RS03950	COG0017	Asparaginyl-tRNA synthetase
STACADC2_RS03965	COG0251	oxidation-reduction process
STACADC2_RS03975	COG0720	synthase
STACADC2_RS04040	COG1278	Cold shock
STACADC2_RS04050	COG3328	transposase activity
STACADC2_RS04055	COG2217	Heavy metal translocating P-type atpase
STACADC2_RS04060	COG3328	transposase activity
STACADC2_RS04065	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STACADC2_RS04075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
STACADC2_RS04080	COG0626	cystathionine gamma-synthase activity
STACADC2_RS04115	COG4975	Glucose uptake
STACADC2_RS04140	COG3443	Belongs to the bacterial solute-binding protein 9 family
STACADC2_RS04140	COG0803	Belongs to the bacterial solute-binding protein 9 family
STACADC2_RS04180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
STACADC2_RS04185	COG2824	Alkylphosphonate utilization operon protein PhnA
STACADC2_RS04190	COG0765	amino acid transport
STACADC2_RS04195	COG1126	abc transporter atp-binding protein
STACADC2_RS04200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STACADC2_RS04210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STACADC2_RS04240	COG3421	Type III restriction
STACADC2_RS04245	COG2189	Belongs to the N(4) N(6)-methyltransferase family
STACADC2_RS04250	COG0519	Catalyzes the synthesis of GMP from XMP
STACADC2_RS04250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
STACADC2_RS04255	COG2188	Transcriptional regulator
STACADC2_RS04265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STACADC2_RS04275	COG1827	regulation of RNA biosynthetic process
STACADC2_RS04285	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STACADC2_RS04295	COG1940	carbohydrate kinase activity
STACADC2_RS04300	COG0758	DNA mediated transformation
STACADC2_RS04305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
STACADC2_RS04375	COG1396	sequence-specific DNA binding
STACADC2_RS04385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
STACADC2_RS04390	COG0010	Belongs to the arginase family
STACADC2_RS04400	COG0028	Belongs to the TPP enzyme family
STACADC2_RS04405	COG3527	Alpha-acetolactate decarboxylase
STACADC2_RS04435	COG1230	cation diffusion facilitator family transporter
STACADC2_RS04445	COG1063	alcohol dehydrogenase
STACADC2_RS04475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STACADC2_RS04515	COG1293	RNA-binding protein homologous to eukaryotic snRNP
STACADC2_RS04520	COG3328	transposase activity
STACADC2_RS04530	COG0047	phosphoribosylformylglycinamidine synthase activity
STACADC2_RS04545	COG0167	dihydroorotate dehydrogenase activity
STACADC2_RS04550	COG1468	defense response to virus
STACADC2_RS04550	COG1518	maintenance of DNA repeat elements
STACADC2_RS04555	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STACADC2_RS04575	COG1337	RAMP superfamily
STACADC2_RS04580	COG1567	CRISPR-associated RAMP protein, Csm4 family
STACADC2_RS04595	COG0284	orotidine-5'-phosphate decarboxylase activity
STACADC2_RS04610	COG3104	oligopeptide transport
STACADC2_RS04660	COG1115	amino acid carrier protein
STACADC2_RS04670	COG2873	o-acetylhomoserine
STACADC2_RS04705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
STACADC2_RS04710	COG0196	riboflavin kinase activity
STACADC2_RS04715	COG1393	Belongs to the ArsC family
STACADC2_RS04725	COG0483	inositol monophosphate 1-phosphatase activity
STACADC2_RS04730	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
STACADC2_RS04730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STACADC2_RS04740	COG0573	inorganic phosphate transmembrane transporter activity
STACADC2_RS04745	COG0581	inorganic phosphate transmembrane transporter activity
STACADC2_RS04760	COG0704	Plays a role in the regulation of phosphate uptake
STACADC2_RS04775	COG0095	Lipoate-protein ligase
STACADC2_RS04790	COG0058	SHG alpha-glucan phosphorylase activity
STACADC2_RS04795	COG1640	4-alpha-glucanotransferase
STACADC2_RS04800	COG1609	Transcriptional regulator
STACADC2_RS04825	COG3842	ATPase activity
STACADC2_RS04830	COG4607	ABC-type enterochelin transport system periplasmic component
STACADC2_RS04835	COG4604	ABC transporter, ATP-binding protein
STACADC2_RS04840	COG4605	iron ion homeostasis
STACADC2_RS04845	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STACADC2_RS04855	COG1523	belongs to the glycosyl hydrolase 13 family
STACADC2_RS04880	COG0508	dehydrogenase complex catalyzes the overall conversion of
STACADC2_RS04885	COG0508	dehydrogenase complex catalyzes the overall conversion of
STACADC2_RS04885	COG0022	dehydrogenase e1 component
STACADC2_RS04890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STACADC2_RS04925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
STACADC2_RS04935	COG4667	esterase of the alpha-beta hydrolase superfamily
STACADC2_RS04960	COG2723	6-phospho-beta-galactosidase activity
STACADC2_RS04975	COG0628	permease
STACADC2_RS05030	COG1442	glycosyl transferase family 8
STACADC2_RS05030	COG1216	Glycosyl transferase, family 2
STACADC2_RS05035	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
STACADC2_RS05045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
STACADC2_RS05070	COG1316	TRANSCRIPTIONal
STACADC2_RS05090	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
STACADC2_RS05100	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
STACADC2_RS05120	COG1573	uracil-dna glycosylase
STACADC2_RS05155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
STACADC2_RS05185	COG0681	Belongs to the peptidase S26 family
STACADC2_RS05195	COG0628	permease
STACADC2_RS05200	COG1051	belongs to the nudix hydrolase family
STACADC2_RS05205	COG2177	Part of the ABC transporter FtsEX involved in
STACADC2_RS05210	COG2884	Cell division ATP-binding protein ftsE
STACADC2_RS05215	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STACADC2_RS05220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
STACADC2_RS05255	COG2348	transferase activity, transferring amino-acyl groups
STACADC2_RS05265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
STACADC2_RS05270	COG5002	protein histidine kinase activity
STACADC2_RS05275	COG0745	RESPONSE REGULATOR receiver
STACADC2_RS05280	COG1126	abc transporter atp-binding protein
STACADC2_RS05285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STACADC2_RS05290	COG0765	amino acid transport
STACADC2_RS05295	COG0765	amino acid transport
STACADC2_RS05320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STACADC2_RS05335	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
STACADC2_RS05340	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
STACADC2_RS05340	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
STACADC2_RS05350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
STACADC2_RS05355	COG1956	GAF domain-containing protein
STACADC2_RS05360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
STACADC2_RS05380	COG0335	large ribosomal subunit rRNA binding
STACADC2_RS05385	COG0038	chloride channel
STACADC2_RS05395	COG0038	chloride channel
STACADC2_RS05400	COG0716	FMN binding
STACADC2_RS05465	COG0469	pyruvate kinase activity
STACADC2_RS05515	COG0167	dihydroorotate dehydrogenase activity
STACADC2_RS05525	COG0776	regulation of translation
STACADC2_RS05535	COG2755	lipolytic protein G-D-S-L family
STACADC2_RS05540	COG1307	EDD domain protein, DegV family
STACADC2_RS05545	COG0497	DNA recombination
STACADC2_RS05550	COG1438	arginine binding
STACADC2_RS05555	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
STACADC2_RS05580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STACADC2_RS05600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
STACADC2_RS05600	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
STACADC2_RS05605	COG0300	oxidoreductase activity
STACADC2_RS05620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
STACADC2_RS05625	COG0772	Belongs to the SEDS family
STACADC2_RS05650	COG0647	UMP catabolic process
STACADC2_RS05660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
STACADC2_RS05685	COG1088	dTDP-glucose 4,6-dehydratase activity
STACADC2_RS05695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
STACADC2_RS05700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
STACADC2_RS05715	COG2384	SAM-dependent methyltransferase
STACADC2_RS05740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STACADC2_RS05745	COG3442	glutamine amidotransferase
STACADC2_RS05750	COG0392	lysyltransferase activity
STACADC2_RS05750	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
STACADC2_RS05765	COG0488	(ABC) transporter
STACADC2_RS05775	COG0513	Belongs to the DEAD box helicase family
STACADC2_RS05805	COG0372	Belongs to the citrate synthase family
STACADC2_RS05810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
STACADC2_RS05815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
STACADC2_RS05820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STACADC2_RS05825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STACADC2_RS05850	COG0346	lactoylglutathione lyase activity
STACADC2_RS05875	COG0488	(ABC) transporter
STACADC2_RS05905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
STACADC2_RS05910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
STACADC2_RS05910	COG1328	CTP reductase activity
STACADC2_RS05945	COG1196	nuclear chromosome segregation
STACADC2_RS05960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STACADC2_RS05980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STACADC2_RS05990	COG1011	Hydrolase
STACADC2_RS05995	COG1760	l-serine dehydratase
STACADC2_RS06000	COG1760	l-serine dehydratase
STACADC2_RS06035	COG2197	response regulator
STACADC2_RS06040	COG4585	Histidine kinase
STACADC2_RS06050	COG1131	(ABC) transporter
STACADC2_RS06065	COG0385	Bile acid
STACADC2_RS06080	COG0577	efflux transmembrane transporter activity
STACADC2_RS06085	COG1136	(ABC) transporter
STACADC2_RS06090	COG5002	protein histidine kinase activity
STACADC2_RS06090	COG2198	Histidine kinase
STACADC2_RS06090	COG0784	Response regulator, receiver
STACADC2_RS06095	COG0745	RESPONSE REGULATOR receiver
STACADC2_RS06110	COG0534	Mate efflux family protein
STACADC2_RS06115	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STACADC2_RS06115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STACADC2_RS06145	COG0531	amino acid
STACADC2_RS06160	COG1959	2 iron, 2 sulfur cluster binding
STACADC2_RS06170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STACADC2_RS06170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STACADC2_RS06175	COG0778	Nitroreductase
STACADC2_RS06185	COG0656	L-ascorbic acid biosynthetic process
STACADC2_RS06245	COG1280	lysine exporter protein (LysE YggA)
STACADC2_RS06260	COG1442	glycosyl transferase family 8
STACADC2_RS06260	COG1216	Glycosyl transferase, family 2
STACADC2_RS06275	COG0419	ATPase involved in DNA repair
STACADC2_RS06280	COG0420	3'-5' exonuclease activity
STACADC2_RS06290	COG3250	beta-galactosidase activity
STACADC2_RS06295	COG2190	(PTS) system
STACADC2_RS06295	COG2211	Major facilitator Superfamily
STACADC2_RS06300	COG2017	converts alpha-aldose to the beta-anomer
STACADC2_RS06305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STACADC2_RS06320	COG1609	Transcriptional regulator
STACADC2_RS06345	COG3064	Membrane
STACADC2_RS06350	COG0488	(ABC) transporter
STACADC2_RS06355	COG1132	(ABC) transporter
STACADC2_RS06410	COG2197	response regulator
STACADC2_RS06415	COG4585	Histidine kinase
STACADC2_RS06430	COG2815	serine threonine protein kinase
STACADC2_RS06430	COG0515	serine threonine protein kinase
STACADC2_RS06440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STACADC2_RS06440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
STACADC2_RS06450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
STACADC2_RS06465	COG0552	protein localization to endoplasmic reticulum
STACADC2_RS06470	COG0561	phosphatase activity
STACADC2_RS06475	COG0561	phosphatase activity
STACADC2_RS06480	COG1725	Transcriptional regulator
STACADC2_RS06485	COG1131	(ABC) transporter
STACADC2_RS06495	COG4608	Belongs to the ABC transporter superfamily
STACADC2_RS06500	COG0444	Belongs to the ABC transporter superfamily
STACADC2_RS06505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STACADC2_RS06510	COG0601	transmembrane transport
STACADC2_RS06515	COG4166	transmembrane transport
STACADC2_RS06525	COG4166	transmembrane transport
STACADC2_RS06530	COG2801	Transposase and inactivated derivatives
STACADC2_RS06540	COG2223	nitrite transmembrane transporter activity
STACADC2_RS06550	COG0280	phosphate acetyltransferase
STACADC2_RS06555	COG0564	pseudouridine synthase activity
STACADC2_RS06565	COG2357	RelA SpoT domain protein
STACADC2_RS06580	COG1104	cysteine desulfurase activity
STACADC2_RS06595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
STACADC2_RS06625	COG1215	transferase activity, transferring glycosyl groups
STACADC2_RS06640	COG1442	glycosyl transferase family 8
STACADC2_RS06640	COG1216	Glycosyl transferase, family 2
STACADC2_RS06660	COG1091	dTDP-4-dehydrorhamnose reductase activity
STACADC2_RS06670	COG0463	Glycosyl transferase, family 2
STACADC2_RS06675	COG2151	metal-sulfur cluster biosynthetic enzyme
STACADC2_RS06680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STACADC2_RS06685	COG0358	DNA primase activity
STACADC2_RS06690	COG1970	mechanosensitive ion channel activity
STACADC2_RS06700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STACADC2_RS06705	COG0436	Aminotransferase
STACADC2_RS06710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STACADC2_RS06715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STACADC2_RS06720	COG1051	belongs to the nudix hydrolase family
STACADC2_RS06745	COG0765	amino acid transport
STACADC2_RS06750	COG1126	abc transporter atp-binding protein
STACADC2_RS06770	COG1187	pseudouridine synthase activity
STACADC2_RS06810	COG0560	Phosphoserine phosphatase
STACADC2_RS06820	COG0187	DNA topoisomerase II activity
STACADC2_RS06830	COG1346	cytolysis
STACADC2_RS06835	COG1380	Effector of murein hydrolase LrgA
STACADC2_RS06845	COG1393	Belongs to the ArsC family
STACADC2_RS06855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
STACADC2_RS06895	COG1177	transmembrane transport
STACADC2_RS06900	COG1176	ABC-type spermidine putrescine transport system, permease component I
STACADC2_RS06940	COG0531	amino acid
STACADC2_RS06945	COG0285	dihydrofolate synthase activity
STACADC2_RS06950	COG1837	Belongs to the UPF0109 family
STACADC2_RS06960	COG3615	Tellurite resistance protein tehB
STACADC2_RS06960	COG0500	methyltransferase
STACADC2_RS06970	COG0708	Exodeoxyribonuclease III
STACADC2_RS06985	COG1597	lipid kinase activity
STACADC2_RS06995	COG4708	membrane
STACADC2_RS07005	COG0024	Methionine aminopeptidase
STACADC2_RS07010	COG4109	DRTGG domain
STACADC2_RS07020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
STACADC2_RS07025	COG0658	competence protein
STACADC2_RS07025	COG2333	competence protein COMEC
STACADC2_RS07030	COG1596	polysaccharide export
STACADC2_RS07030	COG1555	photosystem II stabilization
STACADC2_RS07035	COG0204	Acyl-transferase
STACADC2_RS07045	COG0726	polysaccharide deacetylase
STACADC2_RS07050	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
STACADC2_RS07060	COG0513	Belongs to the DEAD box helicase family
STACADC2_RS07080	COG1396	sequence-specific DNA binding
STACADC2_RS07085	COG2211	Major facilitator Superfamily
STACADC2_RS07100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STACADC2_RS07115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STACADC2_RS07120	COG1126	abc transporter atp-binding protein
STACADC2_RS07125	COG0765	amino acid transport
STACADC2_RS07130	COG0765	amino acid transport
STACADC2_RS07135	COG1181	Belongs to the D-alanine--D-alanine ligase family
STACADC2_RS07145	COG2217	Heavy metal translocating P-type atpase
STACADC2_RS07165	COG0135	phosphoribosylanthranilate isomerase activity
STACADC2_RS07180	COG0512	Glutamine amidotransferase of anthranilate synthase
STACADC2_RS07185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STACADC2_RS07190	COG0287	Prephenate dehydrogenase
STACADC2_RS07190	COG1605	Chorismate mutase
STACADC2_RS07200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STACADC2_RS07225	COG2176	DNA-directed DNA polymerase activity
STACADC2_RS07235	COG2151	metal-sulfur cluster biosynthetic enzyme
STACADC2_RS07245	COG2081	HI0933 family
STACADC2_RS07270	COG1131	(ABC) transporter
STACADC2_RS07275	COG0537	adenosine 5'-monophosphoramidase activity
STACADC2_RS07305	COG2226	methyltransferase
STACADC2_RS07310	COG0799	negative regulation of ribosome biogenesis
STACADC2_RS07315	COG1713	HD superfamily hydrolase involved in NAD metabolism
STACADC2_RS07320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
STACADC2_RS07325	COG1534	Rna-binding protein
STACADC2_RS07330	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STACADC2_RS07335	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
STACADC2_RS07390	COG1335	isochorismatase
STACADC2_RS07400	COG0436	Aminotransferase
STACADC2_RS07405	COG0589	response to stress
STACADC2_RS07420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STACADC2_RS07430	COG1253	flavin adenine dinucleotide binding
STACADC2_RS07435	COG1119	ATPase activity
STACADC2_RS07440	COG0025	NhaP-type Na H and K H
STACADC2_RS07450	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
STACADC2_RS07455	COG1242	4 iron, 4 sulfur cluster binding
STACADC2_RS07460	COG3480	Lon protease (S16) C-terminal proteolytic domain
STACADC2_RS07465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
STACADC2_RS07470	COG0742	ribosomal rna small subunit methyltransferase
STACADC2_RS07475	COG0492	ferredoxin-NADP+ reductase activity
STACADC2_RS07485	COG1126	abc transporter atp-binding protein
STACADC2_RS07495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STACADC2_RS07510	COG1882	Formate acetyltransferase
STACADC2_RS07525	COG0390	transport system, permease component
STACADC2_RS07530	COG4619	ABC transporter
STACADC2_RS07535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
STACADC2_RS07550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STACADC2_RS07555	COG2936	dipeptidyl-peptidase activity
STACADC2_RS07620	COG2274	protein secretion by the type I secretion system
STACADC2_RS07630	COG1132	(ABC) transporter
STACADC2_RS07635	COG1132	(ABC) transporter
STACADC2_RS07655	COG4470	Protein conserved in bacteria
STACADC2_RS07660	COG0737	Belongs to the 5'-nucleotidase family
STACADC2_RS07670	COG0513	Belongs to the DEAD box helicase family
STACADC2_RS07680	COG0768	penicillin binding
STACADC2_RS07710	COG3152	Membrane
STACADC2_RS07720	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
STACADC2_RS07745	COG1074	ATP-dependent DNA helicase activity
STACADC2_RS07750	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
STACADC2_RS07780	COG0561	phosphatase activity
STACADC2_RS07785	COG0252	asparaginase activity
STACADC2_RS07795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STACADC2_RS07800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
STACADC2_RS07810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STACADC2_RS07815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STACADC2_RS07820	COG0653	protein targeting
STACADC2_RS07830	COG1482	cell wall glycoprotein biosynthetic process
STACADC2_RS07835	COG1940	carbohydrate kinase activity
STACADC2_RS07840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STACADC2_RS07840	COG2190	(PTS) system
STACADC2_RS07840	COG1263	PTS System
STACADC2_RS07845	COG1621	beta-fructofuranosidase activity
STACADC2_RS07850	COG1609	Transcriptional regulator
STACADC2_RS07870	COG2131	deaminase
STACADC2_RS07875	COG0006	proline dipeptidase activity
STACADC2_RS07890	COG1131	(ABC) transporter
STACADC2_RS07965	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STACADC2_RS07965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STACADC2_RS07970	COG1193	negative regulation of DNA recombination
STACADC2_RS07990	COG0681	Belongs to the peptidase S26 family
STACADC2_RS07995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
STACADC2_RS08005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
STACADC2_RS08015	COG0456	acetyltransferase
STACADC2_RS08020	COG1214	PFAM Peptidase M22, glycoprotease
STACADC2_RS08040	COG0174	glutamine synthetase
STACADC2_RS08045	COG0789	Transcriptional regulator
STACADC2_RS08095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
STACADC2_RS08130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
STACADC2_RS08140	COG0084	hydrolase, TatD family'
STACADC2_RS08145	COG1832	CoA-binding protein
STACADC2_RS08150	COG3118	belongs to the thioredoxin family
STACADC2_RS08215	COG0706	membrane insertase activity
STACADC2_RS08245	COG4166	transmembrane transport
STACADC2_RS08280	COG0756	dUTP diphosphatase activity
STACADC2_RS08310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STACADC2_RS08320	COG0705	Rhomboid family
STACADC2_RS08320	COG0457	Tetratricopeptide repeat
STACADC2_RS08325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STACADC2_RS08340	COG0647	UMP catabolic process
STACADC2_RS08350	COG2226	methyltransferase
STACADC2_RS08380	COG0425	Belongs to the sulfur carrier protein TusA family
STACADC2_RS08385	COG2391	methyltransferase activity
STACADC2_RS08390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STACADC2_RS08395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STACADC2_RS08405	COG1363	Peptidase, m42
STACADC2_RS08410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
STACADC2_RS08415	COG1266	CAAX protease self-immunity
STACADC2_RS08470	COG1459	type II secretion system
STACADC2_RS08475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STACADC2_RS08510	COG0440	acetolactate synthase activity
STACADC2_RS08515	COG0028	Belongs to the TPP enzyme family
STACADC2_RS08525	COG1461	Dihydroxyacetone kinase
STACADC2_RS08535	COG0534	Mate efflux family protein
STACADC2_RS08555	COG1454	alcohol dehydrogenase
STACADC2_RS08555	COG1012	belongs to the aldehyde dehydrogenase family
STACADC2_RS08560	COG1454	alcohol dehydrogenase
STACADC2_RS08560	COG1012	belongs to the aldehyde dehydrogenase family
STACADC2_RS08565	COG1454	alcohol dehydrogenase
STACADC2_RS08565	COG1012	belongs to the aldehyde dehydrogenase family
STACADC2_RS08575	COG3590	peptidase
STACADC2_RS08590	COG1609	Transcriptional regulator
STACADC2_RS08595	COG2188	Transcriptional regulator
STACADC2_RS08600	COG4475	Protein of unknown function (DUF436)
STACADC2_RS08620	COG0191	fructose-bisphosphate aldolase activity
STACADC2_RS08685	COG0201	protein transport
STACADC2_RS08830	COG3328	transposase activity
STACADC2_RS08850	COG1396	sequence-specific DNA binding
STACADC2_RS08860	COG1132	(ABC) transporter
STACADC2_RS08890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
STACADC2_RS08920	COG1328	CTP reductase activity
STACADC2_RS08935	COG0602	queuosine metabolic process
STACADC2_RS08940	COG3022	response to hydroperoxide
STACADC2_RS08945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STACADC2_RS08980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STACADC2_RS09010	COG2261	transglycosylase associated protein
STACADC2_RS09030	COG3237	CsbD-like
STACADC2_RS09060	COG1511	domain protein
STACADC2_RS09060	COG1511	domain protein
STACADC2_RS09070	COG3759	membrane
STACADC2_RS09090	COG0305	Participates in initiation and elongation during chromosome replication
STACADC2_RS09110	COG0494	nUDIX hydrolase
STACADC2_RS09125	COG0741	lytic transglycosylase activity
STACADC2_RS09130	COG1388	LysM domain
STACADC2_RS09130	COG3584	3D domain protein
STACADC2_RS09135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
STACADC2_RS09150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
STACADC2_RS09160	COG0612	Peptidase, M16
STACADC2_RS09190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STACADC2_RS09195	COG0488	(ABC) transporter
STACADC2_RS09230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STACADC2_RS09235	COG1475	DNA binding
