locus-tag	class	description
CG712_RS00005	COG2183	response to ionizing radiation
CG712_RS00025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CG712_RS00050	COG0826	peptidase U32
CG712_RS00060	COG1268	BioY protein
CG712_RS00070	COG4443	Transcriptional Coactivator p15 (PC4)
CG712_RS00120	COG0406	alpha-ribazole phosphatase activity
CG712_RS00125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG712_RS00170	COG1704	LemA family
CG712_RS00190	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CG712_RS00200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG712_RS00210	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CG712_RS00215	COG0783	Belongs to the Dps family
CG712_RS00220	COG0735	belongs to the Fur family
CG712_RS00225	COG4483	Protein conserved in bacteria
CG712_RS00230	COG1940	carbohydrate kinase activity
CG712_RS00235	COG1217	gtp-binding protein TYPA
CG712_RS00260	COG0849	cell division
CG712_RS00270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CG712_RS00295	COG3599	regulation of cell shape
CG712_RS00325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CG712_RS00330	COG0625	glutathione transferase activity
CG712_RS00335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CG712_RS00340	COG1435	thymidine kinase activity
CG712_RS00350	COG2890	protein-(glutamine-N5) methyltransferase activity
CG712_RS00380	COG1132	(ABC) transporter
CG712_RS00395	COG1696	Membrane protein involved in D-alanine export
CG712_RS00405	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CG712_RS00415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG712_RS00420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CG712_RS00440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG712_RS00445	COG4684	Psort location CytoplasmicMembrane, score
CG712_RS00450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG712_RS00500	COG2813	Specifically methylates the guanine in position
CG712_RS00520	COG0295	cytidine deaminase activity
CG712_RS00525	COG1744	ABC transporter substrate-binding protein PnrA-like
CG712_RS00530	COG3845	ABC transporter
CG712_RS00535	COG4603	Belongs to the binding-protein-dependent transport system permease family
CG712_RS00540	COG1079	Belongs to the binding-protein-dependent transport system permease family
CG712_RS00550	COG1199	ATP-dependent helicase activity
CG712_RS00550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG712_RS00560	COG0436	Aminotransferase
CG712_RS00565	COG0017	Asparaginyl-tRNA synthetase
CG712_RS00580	COG0251	oxidation-reduction process
CG712_RS00590	COG0720	synthase
CG712_RS00650	COG1278	Cold shock
CG712_RS00660	COG3328	transposase activity
CG712_RS00670	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CG712_RS00680	COG4975	Glucose uptake
CG712_RS00705	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG712_RS00705	COG3443	Belongs to the bacterial solute-binding protein 9 family
CG712_RS00730	COG2801	Transposase and inactivated derivatives
CG712_RS00735	COG2801	Transposase and inactivated derivatives
CG712_RS00745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CG712_RS00750	COG2824	Alkylphosphonate utilization operon protein PhnA
CG712_RS00755	COG0765	amino acid transport
CG712_RS00760	COG1126	abc transporter atp-binding protein
CG712_RS00765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS00775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG712_RS00795	COG1064	alcohol dehydrogenase
CG712_RS00800	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CG712_RS00805	COG0519	Catalyzes the synthesis of GMP from XMP
CG712_RS00805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG712_RS00810	COG2188	Transcriptional regulator
CG712_RS00820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG712_RS00830	COG1827	regulation of RNA biosynthetic process
CG712_RS00840	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CG712_RS00850	COG1940	carbohydrate kinase activity
CG712_RS00855	COG0758	DNA mediated transformation
CG712_RS00860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG712_RS00905	COG0481	GTPase activity
CG712_RS00935	COG1396	sequence-specific DNA binding
CG712_RS00945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG712_RS00950	COG0010	Belongs to the arginase family
CG712_RS00960	COG0028	Belongs to the TPP enzyme family
CG712_RS00965	COG3527	Alpha-acetolactate decarboxylase
CG712_RS01010	COG1230	cation diffusion facilitator family transporter
CG712_RS01020	COG1063	alcohol dehydrogenase
CG712_RS01045	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CG712_RS01070	COG0047	phosphoribosylformylglycinamidine synthase activity
CG712_RS01085	COG0167	dihydroorotate dehydrogenase activity
CG712_RS01095	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG712_RS01115	COG1337	RAMP superfamily
CG712_RS01120	COG1567	CRISPR-associated RAMP protein, Csm4 family
CG712_RS01135	COG0284	orotidine-5'-phosphate decarboxylase activity
CG712_RS01150	COG3104	oligopeptide transport
CG712_RS01155	COG0154	amidase activity
CG712_RS01160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS01190	COG1115	amino acid carrier protein
CG712_RS01200	COG2873	o-acetylhomoserine
CG712_RS01235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG712_RS01240	COG0196	riboflavin kinase activity
CG712_RS01245	COG1393	Belongs to the ArsC family
CG712_RS01255	COG0483	inositol monophosphate 1-phosphatase activity
CG712_RS01260	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CG712_RS01260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG712_RS01270	COG0573	inorganic phosphate transmembrane transporter activity
CG712_RS01275	COG0581	inorganic phosphate transmembrane transporter activity
CG712_RS01290	COG0704	Plays a role in the regulation of phosphate uptake
CG712_RS01305	COG0095	Lipoate-protein ligase
CG712_RS01320	COG0058	SHG alpha-glucan phosphorylase activity
CG712_RS01325	COG1640	4-alpha-glucanotransferase
CG712_RS01340	COG2226	methyltransferase
CG712_RS01370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG712_RS01375	COG0805	protein transport
CG712_RS01380	COG0672	)-iron permease
CG712_RS01385	COG2837	iron assimilation
CG712_RS01390	COG2822	iron ion transport
CG712_RS01395	COG4607	ABC-type enterochelin transport system periplasmic component
CG712_RS01400	COG4604	ABC transporter, ATP-binding protein
CG712_RS01410	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG712_RS01425	COG1523	belongs to the glycosyl hydrolase 13 family
CG712_RS01520	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG712_RS01525	COG0022	dehydrogenase e1 component
CG712_RS01525	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG712_RS01530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG712_RS01550	COG1518	maintenance of DNA repeat elements
CG712_RS01565	COG1857	crispr-associated protein
CG712_RS01600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG712_RS01610	COG4667	esterase of the alpha-beta hydrolase superfamily
CG712_RS01640	COG2723	6-phospho-beta-galactosidase activity
CG712_RS01655	COG0628	permease
CG712_RS01710	COG2801	Transposase and inactivated derivatives
CG712_RS01735	COG3328	transposase activity
CG712_RS01745	COG0562	UDP-galactopyranose mutase
CG712_RS01760	COG1216	Glycosyl transferase, family 2
CG712_RS01760	COG1442	glycosyl transferase family 8
CG712_RS01810	COG1316	TRANSCRIPTIONal
CG712_RS01830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CG712_RS01840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CG712_RS01860	COG1573	uracil-dna glycosylase
CG712_RS01895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CG712_RS01925	COG0681	Belongs to the peptidase S26 family
CG712_RS01935	COG0628	permease
CG712_RS01940	COG1051	belongs to the nudix hydrolase family
CG712_RS01945	COG2177	Part of the ABC transporter FtsEX involved in
CG712_RS01950	COG2884	Cell division ATP-binding protein ftsE
CG712_RS01960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CG712_RS01995	COG2348	transferase activity, transferring amino-acyl groups
CG712_RS02005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CG712_RS02010	COG5002	protein histidine kinase activity
CG712_RS02015	COG0745	RESPONSE REGULATOR receiver
CG712_RS02020	COG1126	abc transporter atp-binding protein
CG712_RS02025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS02030	COG0765	amino acid transport
CG712_RS02035	COG0765	amino acid transport
CG712_RS02060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG712_RS02075	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG712_RS02080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CG712_RS02080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CG712_RS02090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG712_RS02095	COG1956	GAF domain-containing protein
CG712_RS02100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG712_RS02120	COG0335	large ribosomal subunit rRNA binding
CG712_RS02125	COG0038	chloride channel
CG712_RS02140	COG0716	FMN binding
CG712_RS02205	COG0469	pyruvate kinase activity
CG712_RS02230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CG712_RS02255	COG0167	dihydroorotate dehydrogenase activity
CG712_RS02265	COG0776	regulation of translation
CG712_RS02280	COG1307	EDD domain protein, DegV family
CG712_RS02285	COG0497	DNA recombination
CG712_RS02290	COG1438	arginine binding
CG712_RS02295	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CG712_RS02320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CG712_RS02340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG712_RS02340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CG712_RS02345	COG0300	oxidoreductase activity
CG712_RS02360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG712_RS02365	COG0772	Belongs to the SEDS family
CG712_RS02385	COG0647	UMP catabolic process
CG712_RS02420	COG1088	dTDP-glucose 4,6-dehydratase activity
CG712_RS02430	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CG712_RS02435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG712_RS02450	COG2384	SAM-dependent methyltransferase
CG712_RS02480	COG3442	glutamine amidotransferase
CG712_RS02485	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CG712_RS02485	COG0392	lysyltransferase activity
CG712_RS02500	COG0488	(ABC) transporter
CG712_RS02510	COG0513	Belongs to the DEAD box helicase family
CG712_RS02540	COG0372	Belongs to the citrate synthase family
CG712_RS02545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG712_RS02550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CG712_RS02555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG712_RS02560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG712_RS02590	COG3764	Sortase (surface protein transpeptidase)
CG712_RS02610	COG0488	(ABC) transporter
CG712_RS02645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG712_RS02650	COG1328	CTP reductase activity
CG712_RS02650	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CG712_RS02685	COG1196	nuclear chromosome segregation
CG712_RS02700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG712_RS02720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG712_RS02730	COG1011	Hydrolase
CG712_RS02735	COG1760	l-serine dehydratase
CG712_RS02740	COG1760	l-serine dehydratase
CG712_RS02765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CG712_RS02770	COG1131	(ABC) transporter
CG712_RS02780	COG2197	response regulator
CG712_RS02785	COG4585	Histidine kinase
CG712_RS02795	COG1131	(ABC) transporter
CG712_RS02830	COG0577	efflux transmembrane transporter activity
CG712_RS02835	COG1136	(ABC) transporter
CG712_RS02840	COG0784	Response regulator, receiver
CG712_RS02840	COG5002	protein histidine kinase activity
CG712_RS02840	COG2198	Histidine kinase
CG712_RS02845	COG0745	RESPONSE REGULATOR receiver
CG712_RS02860	COG0534	Mate efflux family protein
CG712_RS02895	COG0531	amino acid
CG712_RS02915	COG1126	abc transporter atp-binding protein
CG712_RS02920	COG0765	amino acid transport
CG712_RS02925	COG0765	amino acid transport
CG712_RS02930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS02940	COG0386	Belongs to the glutathione peroxidase family
CG712_RS02980	COG1959	2 iron, 2 sulfur cluster binding
CG712_RS02990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CG712_RS02995	COG0778	Nitroreductase
CG712_RS03005	COG0656	L-ascorbic acid biosynthetic process
CG712_RS03015	COG4868	Belongs to the UPF0371 family
CG712_RS03050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG712_RS03065	COG1442	glycosyl transferase family 8
CG712_RS03065	COG1216	Glycosyl transferase, family 2
CG712_RS03075	COG0419	ATPase involved in DNA repair
CG712_RS03080	COG0420	3'-5' exonuclease activity
CG712_RS03095	COG3250	beta-galactosidase activity
CG712_RS03105	COG2017	converts alpha-aldose to the beta-anomer
CG712_RS03110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG712_RS03125	COG1609	Transcriptional regulator
CG712_RS03140	COG0488	(ABC) transporter
CG712_RS03200	COG2197	response regulator
CG712_RS03205	COG4585	Histidine kinase
CG712_RS03220	COG0515	serine threonine protein kinase
CG712_RS03220	COG2815	serine threonine protein kinase
CG712_RS03230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG712_RS03230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG712_RS03240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CG712_RS03255	COG0552	protein localization to endoplasmic reticulum
CG712_RS03260	COG0561	phosphatase activity
CG712_RS03265	COG0561	phosphatase activity
CG712_RS03270	COG1725	Transcriptional regulator
CG712_RS03275	COG1131	(ABC) transporter
CG712_RS03285	COG4608	Belongs to the ABC transporter superfamily
CG712_RS03290	COG0444	Belongs to the ABC transporter superfamily
CG712_RS03295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG712_RS03300	COG0601	transmembrane transport
CG712_RS03305	COG4166	transmembrane transport
CG712_RS03315	COG4166	transmembrane transport
CG712_RS03320	COG2801	Transposase and inactivated derivatives
CG712_RS03325	COG4608	Belongs to the ABC transporter superfamily
CG712_RS03330	COG4608	Belongs to the ABC transporter superfamily
CG712_RS03340	COG2223	nitrite transmembrane transporter activity
CG712_RS03350	COG0280	phosphate acetyltransferase
CG712_RS03355	COG0564	pseudouridine synthase activity
CG712_RS03365	COG2357	RelA SpoT domain protein
CG712_RS03380	COG1104	cysteine desulfurase activity
CG712_RS03395	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CG712_RS03400	COG2003	Belongs to the UPF0758 family
CG712_RS03425	COG1215	transferase activity, transferring glycosyl groups
CG712_RS03435	COG1216	Glycosyl transferase, family 2
CG712_RS03435	COG1442	glycosyl transferase family 8
CG712_RS03455	COG1091	dTDP-4-dehydrorhamnose reductase activity
CG712_RS03465	COG0463	Glycosyl transferase, family 2
CG712_RS03475	COG2151	metal-sulfur cluster biosynthetic enzyme
CG712_RS03480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG712_RS03485	COG0358	DNA primase activity
CG712_RS03500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS03505	COG0436	Aminotransferase
CG712_RS03510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS03515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS03520	COG1051	belongs to the nudix hydrolase family
CG712_RS03540	COG0765	amino acid transport
CG712_RS03545	COG1126	abc transporter atp-binding protein
CG712_RS03565	COG1187	pseudouridine synthase activity
CG712_RS03615	COG0187	DNA topoisomerase II activity
CG712_RS03625	COG1346	cytolysis
CG712_RS03630	COG1380	Effector of murein hydrolase LrgA
CG712_RS03640	COG1393	Belongs to the ArsC family
CG712_RS03650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG712_RS03670	COG0346	lactoylglutathione lyase activity
CG712_RS03685	COG1177	transmembrane transport
CG712_RS03690	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG712_RS03735	COG0531	amino acid
CG712_RS03740	COG0285	dihydrofolate synthase activity
CG712_RS03745	COG1837	Belongs to the UPF0109 family
CG712_RS03755	COG0500	methyltransferase
CG712_RS03755	COG3615	Tellurite resistance protein tehB
CG712_RS03760	COG0708	Exodeoxyribonuclease III
CG712_RS03775	COG1597	lipid kinase activity
CG712_RS03785	COG4708	membrane
CG712_RS03795	COG0024	Methionine aminopeptidase
CG712_RS03800	COG4109	DRTGG domain
CG712_RS03810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CG712_RS03815	COG2333	competence protein COMEC
CG712_RS03815	COG0658	competence protein
CG712_RS03820	COG1596	polysaccharide export
CG712_RS03820	COG1555	photosystem II stabilization
CG712_RS03825	COG0204	Acyl-transferase
CG712_RS03835	COG0726	polysaccharide deacetylase
CG712_RS03840	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CG712_RS03850	COG0513	Belongs to the DEAD box helicase family
CG712_RS03870	COG1396	sequence-specific DNA binding
CG712_RS03890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CG712_RS03905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS03910	COG1126	abc transporter atp-binding protein
CG712_RS03915	COG0765	amino acid transport
CG712_RS03920	COG0765	amino acid transport
CG712_RS03925	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG712_RS03935	COG2217	Heavy metal translocating P-type atpase
CG712_RS03950	COG0133	tryptophan synthase activity
CG712_RS03955	COG0135	phosphoribosylanthranilate isomerase activity
CG712_RS03970	COG0512	Glutamine amidotransferase of anthranilate synthase
CG712_RS03975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CG712_RS03980	COG1605	Chorismate mutase
CG712_RS03980	COG0287	Prephenate dehydrogenase
CG712_RS03990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG712_RS04015	COG2176	DNA-directed DNA polymerase activity
CG712_RS04025	COG2151	metal-sulfur cluster biosynthetic enzyme
CG712_RS04060	COG1131	(ABC) transporter
CG712_RS04065	COG0537	adenosine 5'-monophosphoramidase activity
CG712_RS04095	COG2226	methyltransferase
CG712_RS04100	COG0799	negative regulation of ribosome biogenesis
CG712_RS04105	COG1713	HD superfamily hydrolase involved in NAD metabolism
CG712_RS04110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG712_RS04115	COG1534	Rna-binding protein
CG712_RS04120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CG712_RS04125	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CG712_RS04180	COG1335	isochorismatase
CG712_RS04190	COG0436	Aminotransferase
CG712_RS04195	COG0589	response to stress
CG712_RS04210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CG712_RS04220	COG1253	flavin adenine dinucleotide binding
CG712_RS04225	COG1119	ATPase activity
CG712_RS04230	COG0025	NhaP-type Na H and K H
CG712_RS04240	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CG712_RS04245	COG1242	4 iron, 4 sulfur cluster binding
CG712_RS04250	COG3480	Lon protease (S16) C-terminal proteolytic domain
CG712_RS04255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG712_RS04260	COG0742	ribosomal rna small subunit methyltransferase
CG712_RS04265	COG0492	ferredoxin-NADP+ reductase activity
CG712_RS04275	COG1126	abc transporter atp-binding protein
CG712_RS04285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS04300	COG1882	Formate acetyltransferase
CG712_RS04340	COG0390	transport system, permease component
CG712_RS04345	COG4619	ABC transporter
CG712_RS04350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG712_RS04365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CG712_RS04420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG712_RS04425	COG2274	protein secretion by the type I secretion system
CG712_RS04435	COG1132	(ABC) transporter
CG712_RS04440	COG1132	(ABC) transporter
CG712_RS04455	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CG712_RS04460	COG4470	Protein conserved in bacteria
CG712_RS04465	COG0737	Belongs to the 5'-nucleotidase family
CG712_RS04470	COG0513	Belongs to the DEAD box helicase family
CG712_RS04480	COG0768	penicillin binding
CG712_RS04520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CG712_RS04550	COG1074	ATP-dependent DNA helicase activity
CG712_RS04555	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CG712_RS04585	COG0561	phosphatase activity
CG712_RS04590	COG0252	asparaginase activity
CG712_RS04595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG712_RS04600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG712_RS04610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CG712_RS04615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CG712_RS04620	COG0653	protein targeting
CG712_RS04630	COG1482	cell wall glycoprotein biosynthetic process
CG712_RS04635	COG1940	carbohydrate kinase activity
CG712_RS04640	COG1263	PTS System
CG712_RS04640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG712_RS04640	COG2190	(PTS) system
CG712_RS04645	COG1621	beta-fructofuranosidase activity
CG712_RS04650	COG1609	Transcriptional regulator
CG712_RS04670	COG2131	deaminase
CG712_RS04675	COG0006	proline dipeptidase activity
CG712_RS04685	COG1131	(ABC) transporter
CG712_RS04690	COG1131	(ABC) transporter
CG712_RS04765	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG712_RS04765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG712_RS04770	COG1193	negative regulation of DNA recombination
CG712_RS04790	COG0681	Belongs to the peptidase S26 family
CG712_RS04795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CG712_RS04805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CG712_RS04815	COG0456	acetyltransferase
CG712_RS04820	COG1214	PFAM Peptidase M22, glycoprotease
CG712_RS04840	COG0174	glutamine synthetase
CG712_RS04845	COG0789	Transcriptional regulator
CG712_RS04895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG712_RS04940	COG0084	hydrolase, TatD family'
CG712_RS04945	COG1832	CoA-binding protein
CG712_RS04950	COG3118	belongs to the thioredoxin family
CG712_RS05015	COG0706	membrane insertase activity
CG712_RS05040	COG4166	transmembrane transport
CG712_RS05045	COG4166	transmembrane transport
CG712_RS05080	COG0756	dUTP diphosphatase activity
CG712_RS05115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG712_RS05125	COG0457	Tetratricopeptide repeat
CG712_RS05125	COG0705	Rhomboid family
CG712_RS05130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CG712_RS05150	COG2226	methyltransferase
CG712_RS05180	COG0425	Belongs to the sulfur carrier protein TusA family
CG712_RS05185	COG2391	methyltransferase activity
CG712_RS05190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG712_RS05195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG712_RS05205	COG1363	Peptidase, m42
CG712_RS05210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG712_RS05215	COG1266	CAAX protease self-immunity
CG712_RS05270	COG1459	type II secretion system
CG712_RS05275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG712_RS05310	COG0440	acetolactate synthase activity
CG712_RS05315	COG0028	Belongs to the TPP enzyme family
CG712_RS05325	COG1461	Dihydroxyacetone kinase
CG712_RS05335	COG0534	Mate efflux family protein
CG712_RS05350	COG1454	alcohol dehydrogenase
CG712_RS05350	COG1012	belongs to the aldehyde dehydrogenase family
CG712_RS05355	COG1012	belongs to the aldehyde dehydrogenase family
CG712_RS05355	COG1454	alcohol dehydrogenase
CG712_RS05360	COG1012	belongs to the aldehyde dehydrogenase family
CG712_RS05360	COG1454	alcohol dehydrogenase
CG712_RS05365	COG1012	belongs to the aldehyde dehydrogenase family
CG712_RS05365	COG1454	alcohol dehydrogenase
CG712_RS05370	COG3590	peptidase
CG712_RS05385	COG1609	Transcriptional regulator
CG712_RS05390	COG2188	Transcriptional regulator
CG712_RS05395	COG4475	Protein of unknown function (DUF436)
CG712_RS05415	COG0191	fructose-bisphosphate aldolase activity
CG712_RS05480	COG0201	protein transport
CG712_RS05620	COG3328	transposase activity
CG712_RS05630	COG0515	serine threonine protein kinase
CG712_RS05635	COG1132	(ABC) transporter
CG712_RS05640	COG1396	sequence-specific DNA binding
CG712_RS05650	COG1132	(ABC) transporter
CG712_RS05680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG712_RS05710	COG1328	CTP reductase activity
CG712_RS05725	COG0602	queuosine metabolic process
CG712_RS05735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG712_RS05760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG712_RS05775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG712_RS05800	COG2261	transglycosylase associated protein
CG712_RS05820	COG3237	CsbD-like
CG712_RS05825	COG0494	nUDIX hydrolase
CG712_RS05845	COG1511	domain protein
CG712_RS05845	COG1511	domain protein
CG712_RS05855	COG3759	membrane
CG712_RS05875	COG0305	Participates in initiation and elongation during chromosome replication
CG712_RS05895	COG0494	nUDIX hydrolase
CG712_RS05910	COG0741	lytic transglycosylase activity
CG712_RS05915	COG3584	3D domain protein
CG712_RS05915	COG1388	LysM domain
CG712_RS05920	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG712_RS05935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG712_RS05945	COG0612	Peptidase, M16
CG712_RS05975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG712_RS05980	COG0488	(ABC) transporter
CG712_RS06015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG712_RS06020	COG1475	DNA binding
CG712_RS06030	COG0592	DNA-directed DNA polymerase activity
CG712_RS06040	COG0012	GTP binding
CG712_RS06050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG712_RS06055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CG712_RS06085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG712_RS06215	COG3942	CHAP domain
CG712_RS06230	COG0436	Aminotransferase
CG712_RS06245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG712_RS06255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG712_RS06270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG712_RS06290	COG0151	Belongs to the GarS family
CG712_RS06295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG712_RS06340	COG4550	Control of competence regulator ComK, YlbF/YmcA
CG712_RS06385	COG1546	Belongs to the CinA family
CG712_RS06385	COG1058	Belongs to the CinA family
CG712_RS06395	COG1393	Belongs to the ArsC family
CG712_RS06485	COG2309	aminopeptidase activity
CG712_RS06500	COG0431	NADPH-dependent FMN reductase
CG712_RS06540	COG4463	regulation of RNA biosynthetic process
CG712_RS06545	COG0542	response to heat
CG712_RS06555	COG1686	Belongs to the peptidase S11 family
CG712_RS06570	COG1045	serine acetyltransferase
CG712_RS06580	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CG712_RS06595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG712_RS06620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CG712_RS06685	COG3830	Belongs to the UPF0237 family
CG712_RS06695	COG0588	phosphoglycerate mutase activity
CG712_RS06700	COG1876	peptidase activity
CG712_RS06735	COG0351	phosphomethylpyrimidine kinase
CG712_RS06740	COG4720	Psort location CytoplasmicMembrane, score
CG712_RS06835	COG4166	transmembrane transport
CG712_RS06860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG712_RS06880	COG0668	transmembrane transport
CG712_RS06895	COG0504	CTP synthase activity
CG712_RS06905	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CG712_RS06915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CG712_RS06955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG712_RS06990	COG1126	abc transporter atp-binding protein
CG712_RS06995	COG0765	amino acid transport
CG712_RS07000	COG1968	undecaprenyl-diphosphatase activity
CG712_RS07015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG712_RS07025	COG0719	Fe-S assembly protein
CG712_RS07030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG712_RS07040	COG0719	Fe-S assembly protein
CG712_RS07065	COG4608	Belongs to the ABC transporter superfamily
CG712_RS07080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG712_RS07105	COG1121	(ABC) transporter
CG712_RS07110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG712_RS07150	COG4589	Belongs to the CDS family
CG712_RS07165	COG4120	Belongs to the binding-protein-dependent transport system permease family
CG712_RS07170	COG1116	anion transmembrane transporter activity
CG712_RS07170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG712_RS07205	COG0564	pseudouridine synthase activity
CG712_RS07210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG712_RS07240	COG1349	DNA-binding transcription factor activity
CG712_RS07270	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CG712_RS07285	COG3579	cysteine-type endopeptidase activity
CG712_RS07290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG712_RS07315	COG0116	Belongs to the methyltransferase superfamily
CG712_RS07325	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG712_RS07345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG712_RS07365	COG1254	Belongs to the acylphosphatase family
CG712_RS07370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG712_RS07415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CG712_RS07435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CG712_RS07440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG712_RS07445	COG1187	pseudouridine synthase activity
CG712_RS07455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG712_RS07460	COG0569	domain protein
CG712_RS07470	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CG712_RS07475	COG0671	phosphoesterase, PA-phosphatase related
CG712_RS07485	COG2274	protein secretion by the type I secretion system
CG712_RS07490	COG2274	protein secretion by the type I secretion system
CG712_RS07495	COG2274	protein secretion by the type I secretion system
CG712_RS07500	COG2274	protein secretion by the type I secretion system
CG712_RS07555	COG0310	cobalt ion transport
CG712_RS07565	COG1122	ATPase activity
CG712_RS07570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG712_RS07575	COG1464	Belongs to the NlpA lipoprotein family
CG712_RS07585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CG712_RS07610	COG1122	ATPase activity
CG712_RS07620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CG712_RS07635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG712_RS07650	COG0745	RESPONSE REGULATOR receiver
CG712_RS07655	COG5002	protein histidine kinase activity
CG712_RS07670	COG1484	DNA-dependent DNA replication
CG712_RS07685	COG1132	(ABC) transporter
CG712_RS07700	COG3328	transposase activity
CG712_RS07715	COG3716	PTS system mannose fructose sorbose family IID component
CG712_RS07720	COG3715	PTS system
CG712_RS07730	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CG712_RS07735	COG0561	phosphatase activity
CG712_RS07740	COG2252	PERMEase
CG712_RS07745	COG0802	atpase or kinase
CG712_RS07750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG712_RS07755	COG1316	TRANSCRIPTIONal
CG712_RS07765	COG0195	Participates in both transcription termination and antitermination
CG712_RS07770	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CG712_RS07805	COG2244	polysaccharide biosynthetic process
CG712_RS07810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG712_RS07815	COG0626	cystathionine gamma-synthase activity
CG712_RS07820	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CG712_RS07850	COG4471	UPF0298 protein
CG712_RS07860	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG712_RS07890	COG1739	Uncharacterized protein family UPF0029
CG712_RS07895	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CG712_RS07900	COG1040	competence protein
CG712_RS07985	COG2502	aspartate--ammonia ligase
CG712_RS07990	COG0527	aspartate kinase activity
CG712_RS07995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG712_RS08000	COG1024	Enoyl-CoA hydratase
CG712_RS08005	COG1846	Transcriptional regulator
CG712_RS08025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CG712_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
CG712_RS08035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG712_RS08050	COG0439	Biotin carboxylase
CG712_RS08080	COG0076	glutamate decarboxylase activity
CG712_RS08085	COG0531	amino acid
CG712_RS08110	COG1349	DNA-binding transcription factor activity
CG712_RS08115	COG1105	Belongs to the carbohydrate kinase PfkB family
CG712_RS08125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG712_RS08130	COG0285	dihydrofolate synthase activity
CG712_RS08140	COG1104	cysteine desulfurase activity
CG712_RS08210	COG0488	(ABC) transporter
CG712_RS08230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG712_RS08235	COG0242	peptide deformylase activity
CG712_RS08295	COG1702	phosphate starvation-inducible protein PhoH
CG712_RS08315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG712_RS08315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG712_RS08325	COG0583	DNA-binding transcription factor activity
CG712_RS08345	COG4122	O-methyltransferase activity
CG712_RS08350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG712_RS08380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG712_RS08385	COG0436	Aminotransferase
CG712_RS08400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG712_RS08405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CG712_RS08410	COG0726	polysaccharide deacetylase
CG712_RS08425	COG2962	Rard protein
CG712_RS08455	COG0525	valine-tRNA ligase activity
CG712_RS08465	COG0356	it plays a direct role in the translocation of protons across the membrane
CG712_RS08490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG712_RS08500	COG0772	Belongs to the SEDS family
CG712_RS08520	COG0470	DNA polymerase III
CG712_RS08525	COG1774	PSP1 C-terminal conserved region
CG712_RS08530	COG4467	Involved in initiation control of chromosome replication
CG712_RS08540	COG0004	ammonium transporteR
CG712_RS08545	COG0347	Belongs to the P(II) protein family
CG712_RS08550	COG1388	LysM domain
CG712_RS08550	COG1705	Flagellar rod assembly protein muramidase FlgJ
CG712_RS08600	COG1113	amino acid transport
CG712_RS08650	COG0564	pseudouridine synthase activity
CG712_RS08670	COG0505	Belongs to the CarA family
CG712_RS08700	COG0577	efflux transmembrane transporter activity
CG712_RS08705	COG0577	efflux transmembrane transporter activity
CG712_RS08735	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG712_RS08750	COG3279	Response regulator of the LytR AlgR family
CG712_RS08760	COG1131	(ABC) transporter
CG712_RS08795	COG1187	pseudouridine synthase activity
CG712_RS08800	COG1473	amidohydrolase
CG712_RS08805	COG0686	Belongs to the AlaDH PNT family
CG712_RS08815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG712_RS08880	COG0438	transferase activity, transferring glycosyl groups
CG712_RS08915	COG1272	protein, Hemolysin III
CG712_RS08930	COG3425	synthase
CG712_RS08940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CG712_RS08960	COG0833	amino acid
CG712_RS08965	COG2040	homocysteine
CG712_RS08985	COG0187	DNA topoisomerase II activity
CG712_RS08995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG712_RS09015	COG0539	negative regulation of cytoplasmic translation
CG712_RS09055	COG0494	nUDIX hydrolase
CG712_RS09065	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CG712_RS09070	COG4703	Protein of unknown function (DUF1797)
CG712_RS09075	COG0765	amino acid transport
CG712_RS09110	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG712_RS09115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CG712_RS09120	COG0768	penicillin binding
CG712_RS09125	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CG712_RS09145	COG3711	transcriptional antiterminator
CG712_RS09155	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CG712_RS09160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CG712_RS09165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CG712_RS09170	COG0237	dephospho-CoA kinase activity
CG712_RS09175	COG2814	Major facilitator Superfamily
CG712_RS09190	COG0557	exoribonuclease II activity
CG712_RS09205	COG1185	polyribonucleotide nucleotidyltransferase activity
CG712_RS09210	COG0006	proline dipeptidase activity
CG712_RS09215	COG1609	Transcriptional regulator
CG712_RS09250	COG1368	sulfuric ester hydrolase activity
CG712_RS09255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CG712_RS09305	COG0077	Prephenate dehydratase
CG712_RS09355	COG0270	DNA (cytosine-5-)-methyltransferase activity
CG712_RS09365	COG1393	Belongs to the ArsC family
CG712_RS09505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG712_RS09545	COG3843	relaxase mobilization nuclease domain protein
CG712_RS09575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG712_RS09580	COG2274	protein secretion by the type I secretion system
CG712_RS09605	COG1518	maintenance of DNA repeat elements
CG712_RS09610	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG712_RS09620	COG3689	TIGRFAM TIGR03943 family protein
CG712_RS09625	COG0701	Predicted permease