locus-tag	class	description
STR_RS00010	COG0592	DNA-directed DNA polymerase activity
STR_RS00020	COG0012	GTP binding
STR_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
STR_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
STR_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STR_RS00085	COG2801	Transposase and inactivated derivatives
STR_RS00205	COG3942	CHAP domain
STR_RS00225	COG0436	Aminotransferase
STR_RS00240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STR_RS00250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
STR_RS00265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
STR_RS00290	COG0151	Belongs to the GarS family
STR_RS00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STR_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STR_RS00330	COG4550	Control of competence regulator ComK, YlbF/YmcA
STR_RS00385	COG1393	Belongs to the ArsC family
STR_RS00475	COG2309	aminopeptidase activity
STR_RS00490	COG0431	NADPH-dependent FMN reductase
STR_RS00495	COG2801	Transposase and inactivated derivatives
STR_RS00515	COG1619	proteins homologs of microcin C7 resistance protein MccF
STR_RS00540	COG4463	regulation of RNA biosynthetic process
STR_RS00545	COG0542	response to heat
STR_RS00555	COG1686	Belongs to the peptidase S11 family
STR_RS00570	COG1045	serine acetyltransferase
STR_RS00580	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
STR_RS00590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STR_RS00615	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
STR_RS00675	COG3942	CHAP domain
STR_RS00675	COG1705	Flagellar rod assembly protein muramidase FlgJ
STR_RS00700	COG3830	Belongs to the UPF0237 family
STR_RS00710	COG0588	phosphoglycerate mutase activity
STR_RS00715	COG1876	peptidase activity
STR_RS00750	COG0351	phosphomethylpyrimidine kinase
STR_RS00850	COG4166	transmembrane transport
STR_RS00870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
STR_RS00885	COG0668	transmembrane transport
STR_RS00920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
STR_RS00930	COG0737	Belongs to the 5'-nucleotidase family
STR_RS00935	COG0737	Belongs to the 5'-nucleotidase family
STR_RS00970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
STR_RS01000	COG1126	abc transporter atp-binding protein
STR_RS01005	COG0765	amino acid transport
STR_RS01020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STR_RS01030	COG0719	Fe-S assembly protein
STR_RS01035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
STR_RS01045	COG0719	Fe-S assembly protein
STR_RS01055	COG0601	transmembrane transport
STR_RS01070	COG0444	Belongs to the ABC transporter superfamily
STR_RS01075	COG0444	Belongs to the ABC transporter superfamily
STR_RS01080	COG4608	Belongs to the ABC transporter superfamily
STR_RS01095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
STR_RS01120	COG1121	(ABC) transporter
STR_RS01125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STR_RS01135	COG1263	PTS System
STR_RS01135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STR_RS01135	COG2190	(PTS) system
STR_RS01140	COG2190	(PTS) system
STR_RS01140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STR_RS01140	COG1263	PTS System
STR_RS01145	COG2190	(PTS) system
STR_RS01145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STR_RS01145	COG1263	PTS System
STR_RS01150	COG2190	(PTS) system
STR_RS01150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STR_RS01150	COG1263	PTS System
STR_RS01180	COG4589	Belongs to the CDS family
STR_RS01195	COG4120	Belongs to the binding-protein-dependent transport system permease family
STR_RS01200	COG1116	anion transmembrane transporter activity
STR_RS01200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
STR_RS01225	COG2801	Transposase and inactivated derivatives
STR_RS01240	COG0564	pseudouridine synthase activity
STR_RS01245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STR_RS01270	COG1349	DNA-binding transcription factor activity
STR_RS01300	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
STR_RS01315	COG3579	cysteine-type endopeptidase activity
STR_RS01320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STR_RS01340	COG0116	Belongs to the methyltransferase superfamily
STR_RS01355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
STR_RS01375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
STR_RS01390	COG2801	Transposase and inactivated derivatives
STR_RS01400	COG1254	Belongs to the acylphosphatase family
STR_RS01405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STR_RS01475	COG1187	pseudouridine synthase activity
STR_RS01485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STR_RS01490	COG0569	domain protein
STR_RS01500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
STR_RS01505	COG0671	phosphoesterase, PA-phosphatase related
STR_RS01520	COG2274	protein secretion by the type I secretion system
STR_RS01525	COG2274	protein secretion by the type I secretion system
STR_RS01530	COG2274	protein secretion by the type I secretion system
STR_RS01535	COG2274	protein secretion by the type I secretion system
STR_RS01590	COG0310	cobalt ion transport
STR_RS01600	COG1122	ATPase activity
STR_RS01605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STR_RS01610	COG1464	Belongs to the NlpA lipoprotein family
STR_RS01645	COG1122	ATPase activity
STR_RS01655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
STR_RS01665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STR_RS01680	COG0745	RESPONSE REGULATOR receiver
STR_RS01685	COG5002	protein histidine kinase activity
STR_RS01700	COG1484	DNA-dependent DNA replication
STR_RS01715	COG1132	(ABC) transporter
STR_RS01740	COG3716	PTS system mannose fructose sorbose family IID component
STR_RS01745	COG3715	PTS system
STR_RS01760	COG0561	phosphatase activity
STR_RS01765	COG2252	PERMEase
STR_RS01770	COG0802	atpase or kinase
STR_RS01775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STR_RS01780	COG1316	TRANSCRIPTIONal
STR_RS01790	COG0195	Participates in both transcription termination and antitermination
STR_RS01795	COG2740	Nucleic-acid-binding protein implicated in transcription termination
STR_RS01815	COG1611	Belongs to the LOG family
STR_RS01835	COG2244	polysaccharide biosynthetic process
STR_RS01845	COG0626	cystathionine gamma-synthase activity
STR_RS01850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
STR_RS01875	COG4471	UPF0298 protein
STR_RS01885	COG0559	Belongs to the binding-protein-dependent transport system permease family
STR_RS01905	COG0517	IMP dehydrogenase activity
STR_RS01920	COG1739	Uncharacterized protein family UPF0029
STR_RS01925	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
STR_RS01930	COG1040	competence protein
STR_RS02025	COG0527	aspartate kinase activity
STR_RS02030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STR_RS02035	COG1024	Enoyl-CoA hydratase
STR_RS02040	COG1846	Transcriptional regulator
STR_RS02060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
STR_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
STR_RS02070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STR_RS02085	COG0439	Biotin carboxylase
STR_RS02125	COG1349	DNA-binding transcription factor activity
STR_RS02130	COG1105	Belongs to the carbohydrate kinase PfkB family
STR_RS02140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STR_RS02145	COG0285	dihydrofolate synthase activity
STR_RS02155	COG1104	cysteine desulfurase activity
STR_RS02225	COG0488	(ABC) transporter
STR_RS02245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STR_RS02250	COG0242	peptide deformylase activity
STR_RS02320	COG1702	phosphate starvation-inducible protein PhoH
STR_RS02340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STR_RS02340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STR_RS02370	COG4122	O-methyltransferase activity
STR_RS02375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
STR_RS02400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STR_RS02405	COG0436	Aminotransferase
STR_RS02420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
STR_RS02425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
STR_RS02430	COG0726	polysaccharide deacetylase
STR_RS02445	COG2962	Rard protein
STR_RS02480	COG0356	it plays a direct role in the translocation of protons across the membrane
STR_RS02515	COG0772	Belongs to the SEDS family
STR_RS02535	COG0470	DNA polymerase III
STR_RS02540	COG1774	PSP1 C-terminal conserved region
STR_RS02545	COG4467	Involved in initiation control of chromosome replication
STR_RS02555	COG0004	ammonium transporteR
STR_RS02560	COG0347	Belongs to the P(II) protein family
STR_RS02565	COG1388	LysM domain
STR_RS02565	COG1705	Flagellar rod assembly protein muramidase FlgJ
STR_RS02620	COG1113	amino acid transport
STR_RS02630	COG2190	(PTS) system
STR_RS02630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STR_RS02630	COG1263	PTS System
STR_RS02665	COG0583	DNA-binding transcription factor activity
STR_RS02695	COG0505	Belongs to the CarA family
STR_RS02725	COG0577	efflux transmembrane transporter activity
STR_RS02730	COG0577	efflux transmembrane transporter activity
STR_RS02770	COG3279	Response regulator of the LytR AlgR family
STR_RS02780	COG1131	(ABC) transporter
STR_RS02815	COG1187	pseudouridine synthase activity
STR_RS02820	COG1473	amidohydrolase
STR_RS02825	COG0686	Belongs to the AlaDH PNT family
STR_RS02830	COG0686	Belongs to the AlaDH PNT family
STR_RS02840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STR_RS02905	COG0438	transferase activity, transferring glycosyl groups
STR_RS02935	COG1272	protein, Hemolysin III
STR_RS02945	COG3425	synthase
STR_RS02955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
STR_RS02975	COG0833	amino acid
STR_RS02980	COG2040	homocysteine
STR_RS03000	COG0187	DNA topoisomerase II activity
STR_RS03010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STR_RS03030	COG0539	negative regulation of cytoplasmic translation
STR_RS03065	COG0673	inositol 2-dehydrogenase activity
STR_RS03085	COG0494	nUDIX hydrolase
STR_RS03090	COG0542	response to heat
STR_RS03095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
STR_RS03100	COG4703	Protein of unknown function (DUF1797)
STR_RS03105	COG0765	amino acid transport
STR_RS03140	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
STR_RS03145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STR_RS03150	COG0768	penicillin binding
STR_RS03155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
STR_RS03165	COG3711	transcriptional antiterminator
STR_RS03175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
STR_RS03180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
STR_RS03195	COG2814	Major facilitator Superfamily
STR_RS03205	COG0557	exoribonuclease II activity
STR_RS03220	COG1185	polyribonucleotide nucleotidyltransferase activity
STR_RS03225	COG0006	proline dipeptidase activity
STR_RS03230	COG1609	Transcriptional regulator
STR_RS03255	COG1368	sulfuric ester hydrolase activity
STR_RS03260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
STR_RS03285	COG0287	Prephenate dehydrogenase
STR_RS03310	COG0077	Prephenate dehydratase
STR_RS03370	COG1518	maintenance of DNA repeat elements
STR_RS03375	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STR_RS03385	COG3689	TIGRFAM TIGR03943 family protein
STR_RS03390	COG0701	Predicted permease
STR_RS03395	COG2183	response to ionizing radiation
STR_RS03440	COG0826	peptidase U32
STR_RS03445	COG1268	BioY protein
STR_RS03455	COG4443	Transcriptional Coactivator p15 (PC4)
STR_RS03460	COG1914	H( )-stimulated, divalent metal cation uptake system
STR_RS03470	COG0494	nUDIX hydrolase
STR_RS03555	COG0406	alpha-ribazole phosphatase activity
STR_RS03560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
STR_RS03590	COG4221	oxidoreductase activity
STR_RS03595	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STR_RS03640	COG1704	LemA family
STR_RS03670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
STR_RS03680	COG0783	Belongs to the Dps family
STR_RS03685	COG0735	belongs to the Fur family
STR_RS03690	COG4483	Protein conserved in bacteria
STR_RS03695	COG1940	carbohydrate kinase activity
STR_RS03700	COG1217	gtp-binding protein TYPA
STR_RS03735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STR_RS03755	COG3599	regulation of cell shape
STR_RS03790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STR_RS03795	COG0625	glutathione transferase activity
STR_RS03815	COG2890	protein-(glutamine-N5) methyltransferase activity
STR_RS03845	COG1132	(ABC) transporter
STR_RS03860	COG1696	Membrane protein involved in D-alanine export
STR_RS03870	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
STR_RS03875	COG2801	Transposase and inactivated derivatives
STR_RS03880	COG2801	Transposase and inactivated derivatives
STR_RS03900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STR_RS03905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STR_RS03970	COG0582	viral genome integration into host DNA
STR_RS03990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STR_RS03995	COG4684	Psort location CytoplasmicMembrane, score
STR_RS04000	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STR_RS04025	COG5002	protein histidine kinase activity
STR_RS04030	COG5002	protein histidine kinase activity
STR_RS04035	COG2801	Transposase and inactivated derivatives
STR_RS04055	COG2813	Specifically methylates the guanine in position
STR_RS04080	COG1744	ABC transporter substrate-binding protein PnrA-like
STR_RS04085	COG3845	ABC transporter
STR_RS04090	COG4603	Belongs to the binding-protein-dependent transport system permease family
STR_RS04095	COG1079	Belongs to the binding-protein-dependent transport system permease family
STR_RS04105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
STR_RS04105	COG1199	ATP-dependent helicase activity
STR_RS04115	COG0436	Aminotransferase
STR_RS04145	COG0251	oxidation-reduction process
STR_RS04155	COG0720	synthase
STR_RS04205	COG1278	Cold shock
STR_RS04215	COG3328	transposase activity
STR_RS04220	COG2217	Heavy metal translocating P-type atpase
STR_RS04235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
STR_RS04240	COG0626	cystathionine gamma-synthase activity
STR_RS04250	COG3328	transposase activity
STR_RS04275	COG4975	Glucose uptake
STR_RS04295	COG3443	Belongs to the bacterial solute-binding protein 9 family
STR_RS04295	COG0803	Belongs to the bacterial solute-binding protein 9 family
STR_RS04325	COG3942	CHAP domain
STR_RS04325	COG1705	Flagellar rod assembly protein muramidase FlgJ
STR_RS04340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
STR_RS04345	COG2824	Alkylphosphonate utilization operon protein PhnA
STR_RS04350	COG0765	amino acid transport
STR_RS04355	COG1126	abc transporter atp-binding protein
STR_RS04360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STR_RS04375	COG1064	alcohol dehydrogenase
STR_RS04380	COG1064	alcohol dehydrogenase
STR_RS04385	COG1064	alcohol dehydrogenase
STR_RS04395	COG3421	Type III restriction
STR_RS04400	COG2189	Belongs to the N(4) N(6)-methyltransferase family
STR_RS04410	COG2188	Transcriptional regulator
STR_RS04420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STR_RS04430	COG1827	regulation of RNA biosynthetic process
STR_RS04440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STR_RS04450	COG1940	carbohydrate kinase activity
STR_RS04455	COG0758	DNA mediated transformation
STR_RS04460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
STR_RS04495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
STR_RS04500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STR_RS04530	COG1396	sequence-specific DNA binding
STR_RS04540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
STR_RS04545	COG0010	Belongs to the arginase family
STR_RS04555	COG0028	Belongs to the TPP enzyme family
STR_RS04560	COG3527	Alpha-acetolactate decarboxylase
STR_RS04600	COG1230	cation diffusion facilitator family transporter
STR_RS04660	COG0534	Mate efflux family protein
STR_RS04670	COG1293	RNA-binding protein homologous to eukaryotic snRNP
STR_RS04690	COG0167	dihydroorotate dehydrogenase activity
STR_RS04705	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STR_RS04710	COG1337	RAMP superfamily
STR_RS04715	COG1567	CRISPR-associated RAMP protein, Csm4 family
STR_RS04745	COG3104	oligopeptide transport
STR_RS04760	COG0154	amidase activity
STR_RS04780	COG0737	Belongs to the 5'-nucleotidase family
STR_RS04800	COG1115	amino acid carrier protein
STR_RS04810	COG2873	o-acetylhomoserine
STR_RS04845	COG0196	riboflavin kinase activity
STR_RS04850	COG1393	Belongs to the ArsC family
STR_RS04860	COG0483	inositol monophosphate 1-phosphatase activity
STR_RS04865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STR_RS04865	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
STR_RS04875	COG0573	inorganic phosphate transmembrane transporter activity
STR_RS04880	COG0581	inorganic phosphate transmembrane transporter activity
STR_RS04895	COG0704	Plays a role in the regulation of phosphate uptake
STR_RS04910	COG0095	Lipoate-protein ligase
STR_RS04925	COG0058	SHG alpha-glucan phosphorylase activity
STR_RS04930	COG1640	4-alpha-glucanotransferase
STR_RS04935	COG1609	Transcriptional regulator
STR_RS04955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
STR_RS04960	COG0805	protein transport
STR_RS04965	COG0672	)-iron permease
STR_RS04970	COG2837	iron assimilation
STR_RS04975	COG2822	iron ion transport
STR_RS04980	COG4607	ABC-type enterochelin transport system periplasmic component
STR_RS04985	COG4604	ABC transporter, ATP-binding protein
STR_RS04990	COG4605	iron ion homeostasis
STR_RS04995	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STR_RS05075	COG0508	dehydrogenase complex catalyzes the overall conversion of
STR_RS05080	COG0508	dehydrogenase complex catalyzes the overall conversion of
STR_RS05080	COG0022	dehydrogenase e1 component
STR_RS05085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STR_RS05115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
STR_RS05125	COG4667	esterase of the alpha-beta hydrolase superfamily
STR_RS05150	COG2723	6-phospho-beta-galactosidase activity
STR_RS05165	COG0628	permease
STR_RS05180	COG3328	transposase activity
STR_RS05205	COG5039	Polysaccharide pyruvyl transferase
STR_RS05220	COG1442	glycosyl transferase family 8
STR_RS05220	COG1216	Glycosyl transferase, family 2
STR_RS05225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
STR_RS05245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
STR_RS05265	COG1316	TRANSCRIPTIONal
STR_RS05285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
STR_RS05310	COG1573	uracil-dna glycosylase
STR_RS05375	COG0681	Belongs to the peptidase S26 family
STR_RS05385	COG0628	permease
STR_RS05390	COG1051	belongs to the nudix hydrolase family
STR_RS05395	COG2177	Part of the ABC transporter FtsEX involved in
STR_RS05400	COG2884	Cell division ATP-binding protein ftsE
STR_RS05405	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STR_RS05410	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
STR_RS05445	COG2348	transferase activity, transferring amino-acyl groups
STR_RS05455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
STR_RS05460	COG5002	protein histidine kinase activity
STR_RS05465	COG0745	RESPONSE REGULATOR receiver
STR_RS05470	COG1126	abc transporter atp-binding protein
STR_RS05475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STR_RS05480	COG0765	amino acid transport
STR_RS05485	COG0765	amino acid transport
STR_RS05510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STR_RS05525	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
STR_RS05525	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
STR_RS05535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
STR_RS05540	COG1956	GAF domain-containing protein
STR_RS05560	COG0335	large ribosomal subunit rRNA binding
STR_RS05565	COG0038	chloride channel
STR_RS05575	COG0038	chloride channel
STR_RS05580	COG0716	FMN binding
STR_RS05650	COG0469	pyruvate kinase activity
STR_RS05710	COG0167	dihydroorotate dehydrogenase activity
STR_RS05720	COG0776	regulation of translation
STR_RS05730	COG2755	lipolytic protein G-D-S-L family
STR_RS05735	COG1307	EDD domain protein, DegV family
STR_RS05740	COG0497	DNA recombination
STR_RS05745	COG1438	arginine binding
STR_RS05750	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
STR_RS05775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STR_RS05795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
STR_RS05795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
STR_RS05800	COG0300	oxidoreductase activity
STR_RS05815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
STR_RS05820	COG0772	Belongs to the SEDS family
STR_RS05845	COG0647	UMP catabolic process
STR_RS05855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
STR_RS05875	COG1088	dTDP-glucose 4,6-dehydratase activity
STR_RS05885	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
STR_RS05890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
STR_RS05905	COG2384	SAM-dependent methyltransferase
STR_RS05930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STR_RS05935	COG3442	glutamine amidotransferase
STR_RS05940	COG0392	lysyltransferase activity
STR_RS05940	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
STR_RS05955	COG0488	(ABC) transporter
STR_RS05965	COG0513	Belongs to the DEAD box helicase family
STR_RS05990	COG0372	Belongs to the citrate synthase family
STR_RS05995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
STR_RS06000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
STR_RS06005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STR_RS06010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STR_RS06060	COG0488	(ABC) transporter
STR_RS06085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
STR_RS06090	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
STR_RS06090	COG1328	CTP reductase activity
STR_RS06125	COG1196	nuclear chromosome segregation
STR_RS06140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STR_RS06165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STR_RS06175	COG1011	Hydrolase
STR_RS06180	COG1268	BioY protein
STR_RS06190	COG1125	glycine betaine transport
STR_RS06190	COG0517	IMP dehydrogenase activity
STR_RS06205	COG2986	histidine ammonia-lyase
STR_RS06215	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
STR_RS06220	COG1760	l-serine dehydratase
STR_RS06225	COG1760	l-serine dehydratase
STR_RS06250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
STR_RS06255	COG1131	(ABC) transporter
STR_RS06260	COG2197	response regulator
STR_RS06265	COG4585	Histidine kinase
STR_RS06275	COG1131	(ABC) transporter
STR_RS06290	COG0385	Bile acid
STR_RS06305	COG0577	efflux transmembrane transporter activity
STR_RS06310	COG1136	(ABC) transporter
STR_RS06315	COG2198	Histidine kinase
STR_RS06315	COG0784	Response regulator, receiver
STR_RS06315	COG5002	protein histidine kinase activity
STR_RS06320	COG0745	RESPONSE REGULATOR receiver
STR_RS06330	COG2233	PERMEase
STR_RS06340	COG0534	Mate efflux family protein
STR_RS06345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STR_RS06345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STR_RS06360	COG1126	abc transporter atp-binding protein
STR_RS06365	COG0765	amino acid transport
STR_RS06375	COG2079	MmgE PrpD family protein
STR_RS06390	COG0371	Dehydrogenase
STR_RS06400	COG1473	amidohydrolase
STR_RS06410	COG1482	cell wall glycoprotein biosynthetic process
STR_RS06415	COG1482	cell wall glycoprotein biosynthetic process
STR_RS06425	COG0531	amino acid
STR_RS06440	COG1959	2 iron, 2 sulfur cluster binding
STR_RS06450	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STR_RS06450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STR_RS06455	COG0778	Nitroreductase
STR_RS06465	COG0656	L-ascorbic acid biosynthetic process
STR_RS06520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STR_RS06540	COG1280	lysine exporter protein (LysE YggA)
STR_RS06550	COG1442	glycosyl transferase family 8
STR_RS06550	COG1216	Glycosyl transferase, family 2
STR_RS06565	COG0419	ATPase involved in DNA repair
STR_RS06570	COG0420	3'-5' exonuclease activity
STR_RS06575	COG3250	beta-galactosidase activity
STR_RS06580	COG2211	Major facilitator Superfamily
STR_RS06580	COG2190	(PTS) system
STR_RS06585	COG2017	converts alpha-aldose to the beta-anomer
STR_RS06590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STR_RS06605	COG1609	Transcriptional regulator
STR_RS06625	COG0488	(ABC) transporter
STR_RS06680	COG2197	response regulator
STR_RS06685	COG4585	Histidine kinase
STR_RS06695	COG0515	serine threonine protein kinase
STR_RS06695	COG2815	serine threonine protein kinase
STR_RS06705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
STR_RS06705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STR_RS06715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
STR_RS06730	COG0552	protein localization to endoplasmic reticulum
STR_RS06735	COG0561	phosphatase activity
STR_RS06740	COG0561	phosphatase activity
STR_RS06745	COG1725	Transcriptional regulator
STR_RS06750	COG1131	(ABC) transporter
STR_RS06760	COG4608	Belongs to the ABC transporter superfamily
STR_RS06765	COG0444	Belongs to the ABC transporter superfamily
STR_RS06770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STR_RS06775	COG0601	transmembrane transport
STR_RS06790	COG4166	transmembrane transport
STR_RS06795	COG4608	Belongs to the ABC transporter superfamily
STR_RS06800	COG4608	Belongs to the ABC transporter superfamily
STR_RS06805	COG0084	hydrolase, TatD family'
STR_RS06810	COG2223	nitrite transmembrane transporter activity
STR_RS06815	COG2801	Transposase and inactivated derivatives
STR_RS06825	COG0280	phosphate acetyltransferase
STR_RS06830	COG0564	pseudouridine synthase activity
STR_RS06840	COG2357	RelA SpoT domain protein
STR_RS06855	COG1104	cysteine desulfurase activity
STR_RS06870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
STR_RS06905	COG1215	transferase activity, transferring glycosyl groups
STR_RS06935	COG1216	Glycosyl transferase, family 2
STR_RS06945	COG1091	dTDP-4-dehydrorhamnose reductase activity
STR_RS06950	COG0463	Glycosyl transferase, family 2
STR_RS06955	COG2151	metal-sulfur cluster biosynthetic enzyme
STR_RS06960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STR_RS06965	COG0358	DNA primase activity
STR_RS06980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STR_RS06985	COG0436	Aminotransferase
STR_RS06990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STR_RS06995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STR_RS07000	COG1051	belongs to the nudix hydrolase family
STR_RS07025	COG0765	amino acid transport
STR_RS07030	COG1126	abc transporter atp-binding protein
STR_RS07045	COG1187	pseudouridine synthase activity
STR_RS07080	COG1132	(ABC) transporter
STR_RS07110	COG0560	Phosphoserine phosphatase
STR_RS07120	COG0187	DNA topoisomerase II activity
STR_RS07130	COG1346	cytolysis
STR_RS07135	COG1380	Effector of murein hydrolase LrgA
STR_RS07145	COG1393	Belongs to the ArsC family
STR_RS07155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
STR_RS07190	COG1177	transmembrane transport
STR_RS07195	COG1176	ABC-type spermidine putrescine transport system, permease component I
STR_RS07235	COG0531	amino acid
STR_RS07240	COG0285	dihydrofolate synthase activity
STR_RS07245	COG1837	Belongs to the UPF0109 family
STR_RS07255	COG0500	methyltransferase
STR_RS07255	COG3615	Tellurite resistance protein tehB
STR_RS07265	COG0708	Exodeoxyribonuclease III
STR_RS07280	COG1597	lipid kinase activity
STR_RS07290	COG4708	membrane
STR_RS07300	COG0024	Methionine aminopeptidase
STR_RS07305	COG4109	DRTGG domain
STR_RS07320	COG0658	competence protein
STR_RS07320	COG2333	competence protein COMEC
STR_RS07325	COG1555	photosystem II stabilization
STR_RS07325	COG1596	polysaccharide export
STR_RS07330	COG0204	Acyl-transferase
STR_RS07340	COG0726	polysaccharide deacetylase
STR_RS07345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
STR_RS07355	COG0513	Belongs to the DEAD box helicase family
STR_RS07375	COG1396	sequence-specific DNA binding
STR_RS07380	COG2211	Major facilitator Superfamily
STR_RS07395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STR_RS07410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STR_RS07415	COG1126	abc transporter atp-binding protein
STR_RS07420	COG0765	amino acid transport
STR_RS07425	COG0765	amino acid transport
STR_RS07440	COG2217	Heavy metal translocating P-type atpase
STR_RS07460	COG0135	phosphoribosylanthranilate isomerase activity
STR_RS07475	COG0512	Glutamine amidotransferase of anthranilate synthase
STR_RS07480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STR_RS07485	COG0287	Prephenate dehydrogenase
STR_RS07485	COG1605	Chorismate mutase
STR_RS07495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STR_RS07520	COG2176	DNA-directed DNA polymerase activity
STR_RS07530	COG2151	metal-sulfur cluster biosynthetic enzyme
STR_RS07540	COG2081	HI0933 family
STR_RS07565	COG1131	(ABC) transporter
STR_RS07570	COG0537	adenosine 5'-monophosphoramidase activity
STR_RS07600	COG2226	methyltransferase
STR_RS07605	COG0799	negative regulation of ribosome biogenesis
STR_RS07610	COG1713	HD superfamily hydrolase involved in NAD metabolism
STR_RS07615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
STR_RS07620	COG1534	Rna-binding protein
STR_RS07625	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STR_RS07630	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
STR_RS07680	COG1335	isochorismatase
STR_RS07690	COG0436	Aminotransferase
STR_RS07695	COG0589	response to stress
STR_RS07710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STR_RS07715	COG1253	flavin adenine dinucleotide binding
STR_RS07720	COG1119	ATPase activity
STR_RS07725	COG0025	NhaP-type Na H and K H
STR_RS07735	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
STR_RS07740	COG1242	4 iron, 4 sulfur cluster binding
STR_RS07745	COG3480	Lon protease (S16) C-terminal proteolytic domain
STR_RS07750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
STR_RS07755	COG0742	ribosomal rna small subunit methyltransferase
STR_RS07760	COG0492	ferredoxin-NADP+ reductase activity
STR_RS07770	COG1126	abc transporter atp-binding protein
STR_RS07780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STR_RS07795	COG1882	Formate acetyltransferase
STR_RS07835	COG0390	transport system, permease component
STR_RS07840	COG4619	ABC transporter
STR_RS07850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
STR_RS07870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STR_RS07890	COG2801	Transposase and inactivated derivatives
STR_RS07920	COG2274	protein secretion by the type I secretion system
STR_RS07925	COG1132	(ABC) transporter
STR_RS07930	COG1132	(ABC) transporter
STR_RS07950	COG4470	Protein conserved in bacteria
STR_RS07955	COG0737	Belongs to the 5'-nucleotidase family
STR_RS07960	COG0513	Belongs to the DEAD box helicase family
STR_RS07970	COG0768	penicillin binding
STR_RS08000	COG3152	Membrane
STR_RS08070	COG0561	phosphatase activity
STR_RS08075	COG0252	asparaginase activity
STR_RS08080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STR_RS08095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STR_RS08110	COG1482	cell wall glycoprotein biosynthetic process
STR_RS08115	COG1940	carbohydrate kinase activity
STR_RS08120	COG2190	(PTS) system
STR_RS08120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STR_RS08120	COG1263	PTS System
STR_RS08125	COG1621	beta-fructofuranosidase activity
STR_RS08150	COG2131	deaminase
STR_RS08155	COG0006	proline dipeptidase activity
STR_RS08250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STR_RS08250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STR_RS08275	COG0681	Belongs to the peptidase S26 family
STR_RS08280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
STR_RS08290	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
STR_RS08300	COG0456	acetyltransferase
STR_RS08305	COG1214	PFAM Peptidase M22, glycoprotease
STR_RS08325	COG0174	glutamine synthetase
STR_RS08330	COG0789	Transcriptional regulator
STR_RS08365	COG2801	Transposase and inactivated derivatives
STR_RS08390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
STR_RS08435	COG0084	hydrolase, TatD family'
STR_RS08440	COG1832	CoA-binding protein
STR_RS08445	COG3118	belongs to the thioredoxin family
STR_RS08505	COG0706	membrane insertase activity
STR_RS08570	COG0756	dUTP diphosphatase activity
STR_RS08605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STR_RS08610	COG0705	Rhomboid family
STR_RS08610	COG0457	Tetratricopeptide repeat
STR_RS08615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STR_RS08635	COG2226	methyltransferase
STR_RS08660	COG0425	Belongs to the sulfur carrier protein TusA family
STR_RS08665	COG2391	methyltransferase activity
STR_RS08670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STR_RS08675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STR_RS08685	COG1363	Peptidase, m42
STR_RS08690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
STR_RS08695	COG1266	CAAX protease self-immunity
STR_RS08750	COG1459	type II secretion system
STR_RS08755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STR_RS08775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STR_RS08775	COG4499	WXG100 protein secretion system (Wss), protein YukC
STR_RS08790	COG0440	acetolactate synthase activity
STR_RS08795	COG0028	Belongs to the TPP enzyme family
STR_RS08800	COG0129	dihydroxy-acid dehydratase activity
STR_RS08805	COG1461	Dihydroxyacetone kinase
STR_RS08815	COG0534	Mate efflux family protein
STR_RS08840	COG1012	belongs to the aldehyde dehydrogenase family
STR_RS08840	COG1454	alcohol dehydrogenase
STR_RS08850	COG1454	alcohol dehydrogenase
STR_RS08850	COG1012	belongs to the aldehyde dehydrogenase family
STR_RS08855	COG3590	peptidase
STR_RS08860	COG0366	Alpha amylase catalytic
STR_RS08865	COG0366	Alpha amylase catalytic
STR_RS08875	COG1609	Transcriptional regulator
STR_RS08880	COG2188	Transcriptional regulator
STR_RS08910	COG0191	fructose-bisphosphate aldolase activity
STR_RS08975	COG0201	protein transport
STR_RS09120	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
STR_RS09135	COG0515	serine threonine protein kinase
STR_RS09145	COG1396	sequence-specific DNA binding
STR_RS09155	COG1132	(ABC) transporter
STR_RS09185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
STR_RS09215	COG1328	CTP reductase activity
STR_RS09225	COG0602	queuosine metabolic process
STR_RS09235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STR_RS09255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
STR_RS09260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
STR_RS09270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STR_RS09285	COG1597	lipid kinase activity
STR_RS09300	COG2261	transglycosylase associated protein
STR_RS09320	COG3237	CsbD-like
STR_RS09345	COG1511	domain protein
STR_RS09345	COG1511	domain protein
STR_RS09355	COG3759	membrane
STR_RS09370	COG0305	Participates in initiation and elongation during chromosome replication
STR_RS09400	COG0741	lytic transglycosylase activity
STR_RS09405	COG1388	LysM domain
STR_RS09405	COG3584	3D domain protein
STR_RS09410	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
STR_RS09425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
STR_RS09435	COG0612	Peptidase, M16
STR_RS09465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STR_RS09470	COG0488	(ABC) transporter
STR_RS09505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STR_RS09510	COG1475	DNA binding
STR_RS09555	COG4166	transmembrane transport
STR_RS09560	COG4166	transmembrane transport