locus-tag	class	description
C1A39_RS00010	COG0592	DNA-directed DNA polymerase activity
C1A39_RS00020	COG0012	GTP binding
C1A39_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C1A39_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C1A39_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1A39_RS00195	COG3942	CHAP domain
C1A39_RS00210	COG0436	Aminotransferase
C1A39_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1A39_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1A39_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C1A39_RS00265	COG1388	LysM domain
C1A39_RS00265	COG3942	CHAP domain
C1A39_RS00270	COG0151	Belongs to the GarS family
C1A39_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1A39_RS00295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1A39_RS00310	COG4550	Control of competence regulator ComK, YlbF/YmcA
C1A39_RS00350	COG2818	Glycosylase
C1A39_RS00365	COG1393	Belongs to the ArsC family
C1A39_RS00455	COG2309	aminopeptidase activity
C1A39_RS00510	COG4463	regulation of RNA biosynthetic process
C1A39_RS00515	COG0542	response to heat
C1A39_RS00525	COG1686	Belongs to the peptidase S11 family
C1A39_RS00540	COG1045	serine acetyltransferase
C1A39_RS00550	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C1A39_RS00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1A39_RS00595	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C1A39_RS00660	COG1705	Flagellar rod assembly protein muramidase FlgJ
C1A39_RS00660	COG3942	CHAP domain
C1A39_RS00675	COG3830	Belongs to the UPF0237 family
C1A39_RS00690	COG1876	peptidase activity
C1A39_RS00725	COG0351	phosphomethylpyrimidine kinase
C1A39_RS00730	COG4720	Psort location CytoplasmicMembrane, score
C1A39_RS00835	COG1473	amidohydrolase
C1A39_RS00840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1A39_RS00860	COG0668	transmembrane transport
C1A39_RS00875	COG0504	CTP synthase activity
C1A39_RS00885	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C1A39_RS00895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C1A39_RS00900	COG0737	Belongs to the 5'-nucleotidase family
C1A39_RS00935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1A39_RS00975	COG1126	abc transporter atp-binding protein
C1A39_RS00980	COG0765	amino acid transport
C1A39_RS01000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1A39_RS01010	COG0719	Fe-S assembly protein
C1A39_RS01015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1A39_RS01025	COG0719	Fe-S assembly protein
C1A39_RS01065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1A39_RS01080	COG1121	(ABC) transporter
C1A39_RS01085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1A39_RS01125	COG4589	Belongs to the CDS family
C1A39_RS01140	COG4120	Belongs to the binding-protein-dependent transport system permease family
C1A39_RS01145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1A39_RS01145	COG1116	anion transmembrane transporter activity
C1A39_RS01180	COG0564	pseudouridine synthase activity
C1A39_RS01185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1A39_RS01215	COG1349	DNA-binding transcription factor activity
C1A39_RS01235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C1A39_RS01250	COG3579	cysteine-type endopeptidase activity
C1A39_RS01255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1A39_RS01280	COG0116	Belongs to the methyltransferase superfamily
C1A39_RS01290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1A39_RS01310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1A39_RS01330	COG1254	Belongs to the acylphosphatase family
C1A39_RS01335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1A39_RS01380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C1A39_RS01400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C1A39_RS01405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C1A39_RS01410	COG1187	pseudouridine synthase activity
C1A39_RS01420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1A39_RS01425	COG0569	domain protein
C1A39_RS01435	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C1A39_RS01440	COG0671	phosphoesterase, PA-phosphatase related
C1A39_RS01455	COG2274	protein secretion by the type I secretion system
C1A39_RS01465	COG2274	protein secretion by the type I secretion system
C1A39_RS01515	COG0829	nickel cation binding
C1A39_RS01520	COG0310	cobalt ion transport
C1A39_RS01530	COG1122	ATPase activity
C1A39_RS01535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A39_RS01540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1A39_RS01560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A39_RS01565	COG1464	Belongs to the NlpA lipoprotein family
C1A39_RS01585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1A39_RS01610	COG1122	ATPase activity
C1A39_RS01620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1A39_RS01630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1A39_RS01645	COG0745	RESPONSE REGULATOR receiver
C1A39_RS01650	COG5002	protein histidine kinase activity
C1A39_RS01665	COG1484	DNA-dependent DNA replication
C1A39_RS01705	COG3716	PTS system mannose fructose sorbose family IID component
C1A39_RS01710	COG3715	PTS system
C1A39_RS01720	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C1A39_RS01725	COG0561	phosphatase activity
C1A39_RS01730	COG2252	PERMEase
C1A39_RS01735	COG0802	atpase or kinase
C1A39_RS01740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1A39_RS01745	COG1316	TRANSCRIPTIONal
C1A39_RS01755	COG0195	Participates in both transcription termination and antitermination
C1A39_RS01760	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C1A39_RS01795	COG2244	polysaccharide biosynthetic process
C1A39_RS01800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C1A39_RS01805	COG0626	cystathionine gamma-synthase activity
C1A39_RS01810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C1A39_RS01840	COG4471	UPF0298 protein
C1A39_RS01850	COG0559	Belongs to the binding-protein-dependent transport system permease family
C1A39_RS01880	COG1739	Uncharacterized protein family UPF0029
C1A39_RS01885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C1A39_RS01890	COG1040	competence protein
C1A39_RS01980	COG0527	aspartate kinase activity
C1A39_RS01985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1A39_RS01990	COG1024	Enoyl-CoA hydratase
C1A39_RS01995	COG1846	Transcriptional regulator
C1A39_RS02015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C1A39_RS02020	COG1028	Short-chain dehydrogenase reductase Sdr
C1A39_RS02025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1A39_RS02040	COG0439	Biotin carboxylase
C1A39_RS02080	COG1349	DNA-binding transcription factor activity
C1A39_RS02085	COG1105	Belongs to the carbohydrate kinase PfkB family
C1A39_RS02095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1A39_RS02100	COG0285	dihydrofolate synthase activity
C1A39_RS02110	COG1104	cysteine desulfurase activity
C1A39_RS02170	COG0488	(ABC) transporter
C1A39_RS02190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C1A39_RS02195	COG0242	peptide deformylase activity
C1A39_RS02255	COG1702	phosphate starvation-inducible protein PhoH
C1A39_RS02280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1A39_RS02280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1A39_RS02300	COG4122	O-methyltransferase activity
C1A39_RS02305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1A39_RS02340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1A39_RS02345	COG0436	Aminotransferase
C1A39_RS02360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1A39_RS02365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1A39_RS02370	COG0726	polysaccharide deacetylase
C1A39_RS02385	COG2962	Rard protein
C1A39_RS02420	COG0356	it plays a direct role in the translocation of protons across the membrane
C1A39_RS02455	COG0772	Belongs to the SEDS family
C1A39_RS02475	COG0470	DNA polymerase III
C1A39_RS02480	COG1774	PSP1 C-terminal conserved region
C1A39_RS02485	COG4467	Involved in initiation control of chromosome replication
C1A39_RS02495	COG0004	ammonium transporteR
C1A39_RS02500	COG0347	Belongs to the P(II) protein family
C1A39_RS02505	COG1388	LysM domain
C1A39_RS02505	COG1705	Flagellar rod assembly protein muramidase FlgJ
C1A39_RS02550	COG1113	amino acid transport
C1A39_RS02595	COG0583	DNA-binding transcription factor activity
C1A39_RS02605	COG0564	pseudouridine synthase activity
C1A39_RS02625	COG0505	Belongs to the CarA family
C1A39_RS02665	COG0577	efflux transmembrane transporter activity
C1A39_RS02670	COG0577	efflux transmembrane transporter activity
C1A39_RS02760	COG3279	Response regulator of the LytR AlgR family
C1A39_RS02770	COG1131	(ABC) transporter
C1A39_RS02805	COG1187	pseudouridine synthase activity
C1A39_RS02810	COG1473	amidohydrolase
C1A39_RS02815	COG0686	Belongs to the AlaDH PNT family
C1A39_RS02820	COG0686	Belongs to the AlaDH PNT family
C1A39_RS02825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1A39_RS02895	COG0438	transferase activity, transferring glycosyl groups
C1A39_RS02930	COG1272	protein, Hemolysin III
C1A39_RS02945	COG3425	synthase
C1A39_RS02955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C1A39_RS02975	COG0833	amino acid
C1A39_RS02980	COG2040	homocysteine
C1A39_RS03000	COG0187	DNA topoisomerase II activity
C1A39_RS03010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1A39_RS03030	COG0539	negative regulation of cytoplasmic translation
C1A39_RS03070	COG0494	nUDIX hydrolase
C1A39_RS03075	COG0542	response to heat
C1A39_RS03080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C1A39_RS03085	COG4703	Protein of unknown function (DUF1797)
C1A39_RS03140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C1A39_RS03145	COG0768	penicillin binding
C1A39_RS03150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C1A39_RS03165	COG3711	transcriptional antiterminator
C1A39_RS03175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1A39_RS03180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C1A39_RS03185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1A39_RS03190	COG0237	dephospho-CoA kinase activity
C1A39_RS03210	COG0557	exoribonuclease II activity
C1A39_RS03225	COG1185	polyribonucleotide nucleotidyltransferase activity
C1A39_RS03230	COG0006	proline dipeptidase activity
C1A39_RS03235	COG1609	Transcriptional regulator
C1A39_RS03270	COG1368	sulfuric ester hydrolase activity
C1A39_RS03275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C1A39_RS03300	COG0287	Prephenate dehydrogenase
C1A39_RS03325	COG0077	Prephenate dehydratase
C1A39_RS03435	COG1518	maintenance of DNA repeat elements
C1A39_RS03440	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
C1A39_RS03450	COG3689	TIGRFAM TIGR03943 family protein
C1A39_RS03455	COG0701	Predicted permease
C1A39_RS03460	COG2183	response to ionizing radiation
C1A39_RS03520	COG1268	BioY protein
C1A39_RS03530	COG4443	Transcriptional Coactivator p15 (PC4)
C1A39_RS03540	COG1914	H( )-stimulated, divalent metal cation uptake system
C1A39_RS03550	COG0494	nUDIX hydrolase
C1A39_RS03560	COG3328	transposase activity
C1A39_RS03570	COG1705	Flagellar rod assembly protein muramidase FlgJ
C1A39_RS03570	COG1388	LysM domain
C1A39_RS03585	COG0406	alpha-ribazole phosphatase activity
C1A39_RS03590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1A39_RS03635	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C1A39_RS03685	COG1704	LemA family
C1A39_RS03715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C1A39_RS03725	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C1A39_RS03730	COG0783	Belongs to the Dps family
C1A39_RS03735	COG0735	belongs to the Fur family
C1A39_RS03740	COG4483	Protein conserved in bacteria
C1A39_RS03745	COG1940	carbohydrate kinase activity
C1A39_RS03775	COG0849	cell division
C1A39_RS03785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C1A39_RS03810	COG3599	regulation of cell shape
C1A39_RS03840	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C1A39_RS03845	COG0625	glutathione transferase activity
C1A39_RS03855	COG1435	thymidine kinase activity
C1A39_RS03865	COG2890	protein-(glutamine-N5) methyltransferase activity
C1A39_RS03895	COG1132	(ABC) transporter
C1A39_RS03910	COG1696	Membrane protein involved in D-alanine export
C1A39_RS03920	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C1A39_RS03930	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C1A39_RS03935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1A39_RS03990	COG1396	sequence-specific DNA binding
C1A39_RS03995	COG0582	viral genome integration into host DNA
C1A39_RS04015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1A39_RS04020	COG4684	Psort location CytoplasmicMembrane, score
C1A39_RS04025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1A39_RS04050	COG5002	protein histidine kinase activity
C1A39_RS04055	COG5002	protein histidine kinase activity
C1A39_RS04060	COG5002	protein histidine kinase activity
C1A39_RS04085	COG0038	chloride channel
C1A39_RS04115	COG2813	Specifically methylates the guanine in position
C1A39_RS04130	COG0295	cytidine deaminase activity
C1A39_RS04135	COG1744	ABC transporter substrate-binding protein PnrA-like
C1A39_RS04160	COG1199	ATP-dependent helicase activity
C1A39_RS04160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1A39_RS04170	COG0436	Aminotransferase
C1A39_RS04195	COG0251	oxidation-reduction process
C1A39_RS04205	COG0720	synthase
C1A39_RS04250	COG1278	Cold shock
C1A39_RS04270	COG2217	Heavy metal translocating P-type atpase
C1A39_RS04275	COG3328	transposase activity
C1A39_RS04285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1A39_RS04290	COG0626	cystathionine gamma-synthase activity
C1A39_RS04310	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C1A39_RS04320	COG4975	Glucose uptake
C1A39_RS04340	COG0803	Belongs to the bacterial solute-binding protein 9 family
C1A39_RS04340	COG3443	Belongs to the bacterial solute-binding protein 9 family
C1A39_RS04355	COG3942	CHAP domain
C1A39_RS04355	COG1705	Flagellar rod assembly protein muramidase FlgJ
C1A39_RS04370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1A39_RS04375	COG2824	Alkylphosphonate utilization operon protein PhnA
C1A39_RS04380	COG0765	amino acid transport
C1A39_RS04385	COG1126	abc transporter atp-binding protein
C1A39_RS04390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A39_RS04400	COG1064	alcohol dehydrogenase
C1A39_RS04415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C1A39_RS04415	COG0519	Catalyzes the synthesis of GMP from XMP
C1A39_RS04420	COG2188	Transcriptional regulator
C1A39_RS04430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C1A39_RS04440	COG1827	regulation of RNA biosynthetic process
C1A39_RS04450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C1A39_RS04460	COG1940	carbohydrate kinase activity
C1A39_RS04465	COG0758	DNA mediated transformation
C1A39_RS04470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1A39_RS04530	COG1396	sequence-specific DNA binding
C1A39_RS04540	COG3328	transposase activity
C1A39_RS04550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C1A39_RS04555	COG0010	Belongs to the arginase family
C1A39_RS04565	COG0028	Belongs to the TPP enzyme family
C1A39_RS04570	COG3527	Alpha-acetolactate decarboxylase
C1A39_RS04600	COG1230	cation diffusion facilitator family transporter
C1A39_RS04610	COG1063	alcohol dehydrogenase
C1A39_RS04630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1A39_RS04645	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C1A39_RS04655	COG0047	phosphoribosylformylglycinamidine synthase activity
C1A39_RS04665	COG0167	dihydroorotate dehydrogenase activity
C1A39_RS04670	COG1518	maintenance of DNA repeat elements
C1A39_RS04670	COG1468	defense response to virus
C1A39_RS04675	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
C1A39_RS04695	COG1337	RAMP superfamily
C1A39_RS04700	COG1567	CRISPR-associated RAMP protein, Csm4 family
C1A39_RS04715	COG0284	orotidine-5'-phosphate decarboxylase activity
C1A39_RS04730	COG3104	oligopeptide transport
C1A39_RS04745	COG0737	Belongs to the 5'-nucleotidase family
C1A39_RS04770	COG1115	amino acid carrier protein
C1A39_RS04780	COG2873	o-acetylhomoserine
C1A39_RS04815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C1A39_RS04820	COG0196	riboflavin kinase activity
C1A39_RS04825	COG1393	Belongs to the ArsC family
C1A39_RS04835	COG0483	inositol monophosphate 1-phosphatase activity
C1A39_RS04840	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C1A39_RS04840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1A39_RS04850	COG0573	inorganic phosphate transmembrane transporter activity
C1A39_RS04855	COG0581	inorganic phosphate transmembrane transporter activity
C1A39_RS04870	COG0704	Plays a role in the regulation of phosphate uptake
C1A39_RS04885	COG0095	Lipoate-protein ligase
C1A39_RS04900	COG0058	SHG alpha-glucan phosphorylase activity
C1A39_RS04905	COG1640	4-alpha-glucanotransferase
C1A39_RS04925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1A39_RS04930	COG0805	protein transport
C1A39_RS04935	COG0672	)-iron permease
C1A39_RS04940	COG2837	iron assimilation
C1A39_RS04945	COG2822	iron ion transport
C1A39_RS04950	COG4607	ABC-type enterochelin transport system periplasmic component
C1A39_RS04955	COG4604	ABC transporter, ATP-binding protein
C1A39_RS04960	COG4605	iron ion homeostasis
C1A39_RS04965	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1A39_RS04980	COG1523	belongs to the glycosyl hydrolase 13 family
C1A39_RS04990	COG1523	belongs to the glycosyl hydrolase 13 family
C1A39_RS05010	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1A39_RS05015	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1A39_RS05015	COG0022	dehydrogenase e1 component
C1A39_RS05020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C1A39_RS05040	COG1518	maintenance of DNA repeat elements
C1A39_RS05055	COG1857	crispr-associated protein
C1A39_RS05090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C1A39_RS05100	COG4667	esterase of the alpha-beta hydrolase superfamily
C1A39_RS05140	COG0628	permease
C1A39_RS05150	COG0561	phosphatase activity
C1A39_RS05175	COG0562	UDP-galactopyranose mutase
C1A39_RS05185	COG2244	polysaccharide biosynthetic process
C1A39_RS05190	COG1216	Glycosyl transferase, family 2
C1A39_RS05190	COG1442	glycosyl transferase family 8
C1A39_RS05205	COG1216	Glycosyl transferase, family 2
C1A39_RS05205	COG1442	glycosyl transferase family 8
C1A39_RS05255	COG1316	TRANSCRIPTIONal
C1A39_RS05260	COG3328	transposase activity
C1A39_RS05280	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C1A39_RS05290	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C1A39_RS05310	COG1573	uracil-dna glycosylase
C1A39_RS05375	COG0681	Belongs to the peptidase S26 family
C1A39_RS05385	COG0628	permease
C1A39_RS05390	COG1051	belongs to the nudix hydrolase family
C1A39_RS05395	COG2177	Part of the ABC transporter FtsEX involved in
C1A39_RS05400	COG2884	Cell division ATP-binding protein ftsE
C1A39_RS05410	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C1A39_RS05445	COG2348	transferase activity, transferring amino-acyl groups
C1A39_RS05455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C1A39_RS05460	COG5002	protein histidine kinase activity
C1A39_RS05465	COG0745	RESPONSE REGULATOR receiver
C1A39_RS05470	COG1126	abc transporter atp-binding protein
C1A39_RS05475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A39_RS05480	COG0765	amino acid transport
C1A39_RS05485	COG0765	amino acid transport
C1A39_RS05510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1A39_RS05520	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C1A39_RS05525	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C1A39_RS05525	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C1A39_RS05535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C1A39_RS05540	COG1956	GAF domain-containing protein
C1A39_RS05545	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C1A39_RS05560	COG0335	large ribosomal subunit rRNA binding
C1A39_RS05565	COG0038	chloride channel
C1A39_RS05575	COG0038	chloride channel
C1A39_RS05580	COG0716	FMN binding
C1A39_RS05645	COG0469	pyruvate kinase activity
C1A39_RS05695	COG0167	dihydroorotate dehydrogenase activity
C1A39_RS05705	COG0776	regulation of translation
C1A39_RS05715	COG2755	lipolytic protein G-D-S-L family
C1A39_RS05720	COG1307	EDD domain protein, DegV family
C1A39_RS05725	COG0497	DNA recombination
C1A39_RS05730	COG1438	arginine binding
C1A39_RS05735	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C1A39_RS05760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C1A39_RS05780	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C1A39_RS05780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C1A39_RS05785	COG0300	oxidoreductase activity
C1A39_RS05810	COG0772	Belongs to the SEDS family
C1A39_RS05825	COG0107	imidazoleglycerol-phosphate synthase activity
C1A39_RS05835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1A39_RS05845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1A39_RS05885	COG0647	UMP catabolic process
C1A39_RS05895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1A39_RS05930	COG1088	dTDP-glucose 4,6-dehydratase activity
C1A39_RS05940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C1A39_RS05945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1A39_RS05960	COG2384	SAM-dependent methyltransferase
C1A39_RS05985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C1A39_RS05990	COG3442	glutamine amidotransferase
C1A39_RS05995	COG0392	lysyltransferase activity
C1A39_RS05995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C1A39_RS06005	COG0488	(ABC) transporter
C1A39_RS06015	COG0513	Belongs to the DEAD box helicase family
C1A39_RS06050	COG0372	Belongs to the citrate synthase family
C1A39_RS06055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C1A39_RS06060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1A39_RS06065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1A39_RS06070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1A39_RS06100	COG3764	Sortase (surface protein transpeptidase)
C1A39_RS06120	COG0488	(ABC) transporter
C1A39_RS06145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1A39_RS06150	COG1328	CTP reductase activity
C1A39_RS06150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C1A39_RS06175	COG1196	nuclear chromosome segregation
C1A39_RS06190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1A39_RS06205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1A39_RS06215	COG1011	Hydrolase
C1A39_RS06220	COG1760	l-serine dehydratase
C1A39_RS06250	COG2197	response regulator
C1A39_RS06255	COG4585	Histidine kinase
C1A39_RS06265	COG1131	(ABC) transporter
C1A39_RS06335	COG0577	efflux transmembrane transporter activity
C1A39_RS06340	COG1136	(ABC) transporter
C1A39_RS06345	COG0784	Response regulator, receiver
C1A39_RS06345	COG5002	protein histidine kinase activity
C1A39_RS06345	COG2198	Histidine kinase
C1A39_RS06350	COG0745	RESPONSE REGULATOR receiver
C1A39_RS06365	COG0534	Mate efflux family protein
C1A39_RS06370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1A39_RS06370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1A39_RS06390	COG0531	amino acid
C1A39_RS06400	COG2514	catechol 2,3-dioxygenase activity
C1A39_RS06405	COG1959	2 iron, 2 sulfur cluster binding
C1A39_RS06415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C1A39_RS06420	COG0778	Nitroreductase
C1A39_RS06430	COG0656	L-ascorbic acid biosynthetic process
C1A39_RS06435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1A39_RS06470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1A39_RS06500	COG1280	lysine exporter protein (LysE YggA)
C1A39_RS06510	COG1216	Glycosyl transferase, family 2
C1A39_RS06510	COG1442	glycosyl transferase family 8
C1A39_RS06515	COG0577	efflux transmembrane transporter activity
C1A39_RS06570	COG1396	sequence-specific DNA binding
C1A39_RS06590	COG0419	ATPase involved in DNA repair
C1A39_RS06595	COG0420	3'-5' exonuclease activity
C1A39_RS06605	COG3250	beta-galactosidase activity
C1A39_RS06610	COG2190	(PTS) system
C1A39_RS06610	COG2211	Major facilitator Superfamily
C1A39_RS06615	COG2017	converts alpha-aldose to the beta-anomer
C1A39_RS06620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1A39_RS06635	COG1609	Transcriptional regulator
C1A39_RS06660	COG0488	(ABC) transporter
C1A39_RS06725	COG2197	response regulator
C1A39_RS06730	COG4585	Histidine kinase
C1A39_RS06745	COG0515	serine threonine protein kinase
C1A39_RS06745	COG2815	serine threonine protein kinase
C1A39_RS06755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1A39_RS06755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1A39_RS06765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C1A39_RS06780	COG0552	protein localization to endoplasmic reticulum
C1A39_RS06785	COG0561	phosphatase activity
C1A39_RS06790	COG0561	phosphatase activity
C1A39_RS06795	COG1725	Transcriptional regulator
C1A39_RS06800	COG1131	(ABC) transporter
C1A39_RS06810	COG4608	Belongs to the ABC transporter superfamily
C1A39_RS06815	COG0444	Belongs to the ABC transporter superfamily
C1A39_RS06820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1A39_RS06825	COG0601	transmembrane transport
C1A39_RS06830	COG4166	transmembrane transport
C1A39_RS06840	COG4166	transmembrane transport
C1A39_RS06855	COG4608	Belongs to the ABC transporter superfamily
C1A39_RS06860	COG4608	Belongs to the ABC transporter superfamily
C1A39_RS06865	COG0084	hydrolase, TatD family'
C1A39_RS06870	COG2223	nitrite transmembrane transporter activity
C1A39_RS06880	COG0280	phosphate acetyltransferase
C1A39_RS06885	COG0564	pseudouridine synthase activity
C1A39_RS06895	COG2357	RelA SpoT domain protein
C1A39_RS06910	COG1104	cysteine desulfurase activity
C1A39_RS06925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C1A39_RS06930	COG2003	Belongs to the UPF0758 family
C1A39_RS06955	COG1215	transferase activity, transferring glycosyl groups
C1A39_RS06970	COG1216	Glycosyl transferase, family 2
C1A39_RS06970	COG1442	glycosyl transferase family 8
C1A39_RS06990	COG1091	dTDP-4-dehydrorhamnose reductase activity
C1A39_RS07000	COG0463	Glycosyl transferase, family 2
C1A39_RS07005	COG2151	metal-sulfur cluster biosynthetic enzyme
C1A39_RS07010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1A39_RS07015	COG0358	DNA primase activity
C1A39_RS07035	COG0436	Aminotransferase
C1A39_RS07040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A39_RS07045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A39_RS07050	COG1051	belongs to the nudix hydrolase family
C1A39_RS07070	COG0765	amino acid transport
C1A39_RS07075	COG1126	abc transporter atp-binding protein
C1A39_RS07095	COG1187	pseudouridine synthase activity
C1A39_RS07140	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
C1A39_RS07145	COG1518	maintenance of DNA repeat elements
C1A39_RS07150	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
C1A39_RS07155	COG0560	Phosphoserine phosphatase
C1A39_RS07165	COG0187	DNA topoisomerase II activity
C1A39_RS07175	COG1346	cytolysis
C1A39_RS07180	COG1380	Effector of murein hydrolase LrgA
C1A39_RS07190	COG1393	Belongs to the ArsC family
C1A39_RS07200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1A39_RS07235	COG1177	transmembrane transport
C1A39_RS07240	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1A39_RS07280	COG0531	amino acid
C1A39_RS07285	COG0285	dihydrofolate synthase activity
C1A39_RS07290	COG1837	Belongs to the UPF0109 family
C1A39_RS07300	COG0500	methyltransferase
C1A39_RS07300	COG3615	Tellurite resistance protein tehB
C1A39_RS07310	COG0708	Exodeoxyribonuclease III
C1A39_RS07325	COG1597	lipid kinase activity
C1A39_RS07335	COG4708	membrane
C1A39_RS07345	COG0024	Methionine aminopeptidase
C1A39_RS07350	COG4109	DRTGG domain
C1A39_RS07360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C1A39_RS07365	COG0658	competence protein
C1A39_RS07365	COG2333	competence protein COMEC
C1A39_RS07370	COG1596	polysaccharide export
C1A39_RS07370	COG1555	photosystem II stabilization
C1A39_RS07375	COG0204	Acyl-transferase
C1A39_RS07380	COG0726	polysaccharide deacetylase
C1A39_RS07385	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C1A39_RS07395	COG0513	Belongs to the DEAD box helicase family
C1A39_RS07415	COG1396	sequence-specific DNA binding
C1A39_RS07420	COG2211	Major facilitator Superfamily
C1A39_RS07435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C1A39_RS07445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A39_RS07450	COG1126	abc transporter atp-binding protein
C1A39_RS07455	COG0765	amino acid transport
C1A39_RS07475	COG2217	Heavy metal translocating P-type atpase
C1A39_RS07485	COG0159	tryptophan synthase activity
C1A39_RS07495	COG0135	phosphoribosylanthranilate isomerase activity
C1A39_RS07510	COG0512	Glutamine amidotransferase of anthranilate synthase
C1A39_RS07515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1A39_RS07520	COG1605	Chorismate mutase
C1A39_RS07520	COG0287	Prephenate dehydrogenase
C1A39_RS07530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C1A39_RS07555	COG2176	DNA-directed DNA polymerase activity
C1A39_RS07565	COG2151	metal-sulfur cluster biosynthetic enzyme
C1A39_RS07575	COG2081	HI0933 family
C1A39_RS07600	COG1131	(ABC) transporter
C1A39_RS07605	COG0537	adenosine 5'-monophosphoramidase activity
C1A39_RS07635	COG2226	methyltransferase
C1A39_RS07640	COG0799	negative regulation of ribosome biogenesis
C1A39_RS07645	COG1713	HD superfamily hydrolase involved in NAD metabolism
C1A39_RS07650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1A39_RS07655	COG1534	Rna-binding protein
C1A39_RS07660	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C1A39_RS07665	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C1A39_RS07705	COG2723	6-phospho-beta-galactosidase activity
C1A39_RS07720	COG1335	isochorismatase
C1A39_RS07730	COG0436	Aminotransferase
C1A39_RS07735	COG0589	response to stress
C1A39_RS07755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1A39_RS07765	COG1253	flavin adenine dinucleotide binding
C1A39_RS07770	COG1119	ATPase activity
C1A39_RS07775	COG0025	NhaP-type Na H and K H
C1A39_RS07785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C1A39_RS07790	COG1242	4 iron, 4 sulfur cluster binding
C1A39_RS07795	COG3480	Lon protease (S16) C-terminal proteolytic domain
C1A39_RS07800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C1A39_RS07805	COG0742	ribosomal rna small subunit methyltransferase
C1A39_RS07810	COG0492	ferredoxin-NADP+ reductase activity
C1A39_RS07820	COG1126	abc transporter atp-binding protein
C1A39_RS07830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A39_RS07845	COG1882	Formate acetyltransferase
C1A39_RS07870	COG0390	transport system, permease component
C1A39_RS07875	COG4619	ABC transporter
C1A39_RS07880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C1A39_RS07895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1A39_RS07970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A39_RS07975	COG2274	protein secretion by the type I secretion system
C1A39_RS07980	COG2274	protein secretion by the type I secretion system
C1A39_RS07985	COG1132	(ABC) transporter
C1A39_RS07990	COG1132	(ABC) transporter
C1A39_RS08005	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C1A39_RS08010	COG4470	Protein conserved in bacteria
C1A39_RS08015	COG0737	Belongs to the 5'-nucleotidase family
C1A39_RS08020	COG0513	Belongs to the DEAD box helicase family
C1A39_RS08030	COG0768	penicillin binding
C1A39_RS08055	COG3152	Membrane
C1A39_RS08065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C1A39_RS08080	COG4152	abc transporter atp-binding protein
C1A39_RS08085	COG1811	Na channel or pump
C1A39_RS08125	COG0561	phosphatase activity
C1A39_RS08130	COG0252	asparaginase activity
C1A39_RS08140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1A39_RS08145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1A39_RS08155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1A39_RS08160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1A39_RS08175	COG1482	cell wall glycoprotein biosynthetic process
C1A39_RS08180	COG1940	carbohydrate kinase activity
C1A39_RS08185	COG1263	PTS System
C1A39_RS08185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1A39_RS08185	COG2190	(PTS) system
C1A39_RS08190	COG1621	beta-fructofuranosidase activity
C1A39_RS08195	COG1609	Transcriptional regulator
C1A39_RS08215	COG2131	deaminase
C1A39_RS08220	COG0006	proline dipeptidase activity
C1A39_RS08235	COG1131	(ABC) transporter
C1A39_RS08310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1A39_RS08310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1A39_RS08335	COG0681	Belongs to the peptidase S26 family
C1A39_RS08340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1A39_RS08360	COG0456	acetyltransferase
C1A39_RS08365	COG1214	PFAM Peptidase M22, glycoprotease
C1A39_RS08385	COG0174	glutamine synthetase
C1A39_RS08390	COG0789	Transcriptional regulator
C1A39_RS08450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C1A39_RS08495	COG0084	hydrolase, TatD family'
C1A39_RS08500	COG1832	CoA-binding protein
C1A39_RS08505	COG3118	belongs to the thioredoxin family
C1A39_RS08575	COG0706	membrane insertase activity
C1A39_RS08635	COG0756	dUTP diphosphatase activity
C1A39_RS08645	COG0431	NADPH-dependent FMN reductase
C1A39_RS08645	COG1053	succinate dehydrogenase
C1A39_RS08645	COG3976	FMN-binding domain protein
C1A39_RS08670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C1A39_RS08675	COG0705	Rhomboid family
C1A39_RS08675	COG0457	Tetratricopeptide repeat
C1A39_RS08680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C1A39_RS08700	COG2226	methyltransferase
C1A39_RS08725	COG0425	Belongs to the sulfur carrier protein TusA family
C1A39_RS08730	COG2391	methyltransferase activity
C1A39_RS08735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1A39_RS08740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1A39_RS08750	COG1363	Peptidase, m42
C1A39_RS08755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C1A39_RS08760	COG1266	CAAX protease self-immunity
C1A39_RS08815	COG1459	type II secretion system
C1A39_RS08820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1A39_RS08855	COG0440	acetolactate synthase activity
C1A39_RS08860	COG0028	Belongs to the TPP enzyme family
C1A39_RS08870	COG1461	Dihydroxyacetone kinase
C1A39_RS08880	COG0534	Mate efflux family protein
C1A39_RS08895	COG1454	alcohol dehydrogenase
C1A39_RS08895	COG1012	belongs to the aldehyde dehydrogenase family
C1A39_RS08900	COG1454	alcohol dehydrogenase
C1A39_RS08900	COG1012	belongs to the aldehyde dehydrogenase family
C1A39_RS08905	COG1454	alcohol dehydrogenase
C1A39_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
C1A39_RS08915	COG1012	belongs to the aldehyde dehydrogenase family
C1A39_RS08915	COG1454	alcohol dehydrogenase
C1A39_RS08920	COG3590	peptidase
C1A39_RS08925	COG0366	Alpha amylase catalytic
C1A39_RS08930	COG0366	Alpha amylase catalytic
C1A39_RS08935	COG0366	Alpha amylase catalytic
C1A39_RS08945	COG1609	Transcriptional regulator
C1A39_RS08950	COG2188	Transcriptional regulator
C1A39_RS08955	COG4475	Protein of unknown function (DUF436)
C1A39_RS08985	COG0640	Transcriptional regulator
C1A39_RS08990	COG2217	Heavy metal translocating P-type atpase
C1A39_RS09015	COG3328	transposase activity
C1A39_RS09020	COG0582	viral genome integration into host DNA
C1A39_RS09025	COG0191	fructose-bisphosphate aldolase activity
C1A39_RS09090	COG0201	protein transport
C1A39_RS09235	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C1A39_RS09250	COG0515	serine threonine protein kinase
C1A39_RS09255	COG1132	(ABC) transporter
C1A39_RS09260	COG1396	sequence-specific DNA binding
C1A39_RS09265	COG1396	sequence-specific DNA binding
C1A39_RS09275	COG1132	(ABC) transporter
C1A39_RS09310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C1A39_RS09350	COG0602	queuosine metabolic process
C1A39_RS09360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1A39_RS09385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C1A39_RS09395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C1A39_RS09425	COG2261	transglycosylase associated protein
C1A39_RS09445	COG3237	CsbD-like
C1A39_RS09460	COG3328	transposase activity
C1A39_RS09480	COG1511	domain protein
C1A39_RS09480	COG1511	domain protein
C1A39_RS09490	COG3759	membrane
C1A39_RS09510	COG0305	Participates in initiation and elongation during chromosome replication
C1A39_RS09530	COG0494	nUDIX hydrolase
C1A39_RS09545	COG0741	lytic transglycosylase activity
C1A39_RS09550	COG1388	LysM domain
C1A39_RS09550	COG3584	3D domain protein
C1A39_RS09555	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C1A39_RS09570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1A39_RS09580	COG0612	Peptidase, M16
C1A39_RS09610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C1A39_RS09615	COG0488	(ABC) transporter
C1A39_RS09650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1A39_RS09655	COG1475	DNA binding