locus-tag	class	description
IM723_RS00010	COG0592	DNA-directed DNA polymerase activity
IM723_RS00020	COG0012	GTP binding
IM723_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IM723_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IM723_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IM723_RS00195	COG3942	CHAP domain
IM723_RS00210	COG0436	Aminotransferase
IM723_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM723_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM723_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IM723_RS00270	COG0151	Belongs to the GarS family
IM723_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IM723_RS00295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM723_RS00310	COG4550	Control of competence regulator ComK, YlbF/YmcA
IM723_RS00355	COG1546	Belongs to the CinA family
IM723_RS00355	COG1058	Belongs to the CinA family
IM723_RS00365	COG1393	Belongs to the ArsC family
IM723_RS00455	COG2309	aminopeptidase activity
IM723_RS00470	COG0431	NADPH-dependent FMN reductase
IM723_RS00510	COG4463	regulation of RNA biosynthetic process
IM723_RS00515	COG0542	response to heat
IM723_RS00525	COG1686	Belongs to the peptidase S11 family
IM723_RS00540	COG1045	serine acetyltransferase
IM723_RS00550	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IM723_RS00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM723_RS00595	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IM723_RS00665	COG3830	Belongs to the UPF0237 family
IM723_RS00675	COG0588	phosphoglycerate mutase activity
IM723_RS00680	COG1876	peptidase activity
IM723_RS00715	COG0351	phosphomethylpyrimidine kinase
IM723_RS00720	COG4720	Psort location CytoplasmicMembrane, score
IM723_RS00815	COG4166	transmembrane transport
IM723_RS00840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM723_RS00860	COG0668	transmembrane transport
IM723_RS00875	COG0504	CTP synthase activity
IM723_RS00885	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
IM723_RS00895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IM723_RS00900	COG0737	Belongs to the 5'-nucleotidase family
IM723_RS00950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IM723_RS00990	COG1126	abc transporter atp-binding protein
IM723_RS00995	COG0765	amino acid transport
IM723_RS01000	COG1968	undecaprenyl-diphosphatase activity
IM723_RS01010	COG4862	establishment of competence for transformation
IM723_RS01015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM723_RS01025	COG0719	Fe-S assembly protein
IM723_RS01030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM723_RS01040	COG0719	Fe-S assembly protein
IM723_RS01070	COG4608	Belongs to the ABC transporter superfamily
IM723_RS01085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM723_RS01110	COG1121	(ABC) transporter
IM723_RS01115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM723_RS01155	COG4589	Belongs to the CDS family
IM723_RS01170	COG4120	Belongs to the binding-protein-dependent transport system permease family
IM723_RS01175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM723_RS01175	COG1116	anion transmembrane transporter activity
IM723_RS01210	COG0564	pseudouridine synthase activity
IM723_RS01215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM723_RS01265	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IM723_RS01280	COG3579	cysteine-type endopeptidase activity
IM723_RS01285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM723_RS01310	COG0116	Belongs to the methyltransferase superfamily
IM723_RS01320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM723_RS01340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IM723_RS01360	COG1254	Belongs to the acylphosphatase family
IM723_RS01365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM723_RS01410	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IM723_RS01430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IM723_RS01435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IM723_RS01440	COG1187	pseudouridine synthase activity
IM723_RS01450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM723_RS01455	COG0569	domain protein
IM723_RS01465	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IM723_RS01470	COG0671	phosphoesterase, PA-phosphatase related
IM723_RS01485	COG2274	protein secretion by the type I secretion system
IM723_RS01500	COG2274	protein secretion by the type I secretion system
IM723_RS01555	COG0310	cobalt ion transport
IM723_RS01565	COG1122	ATPase activity
IM723_RS01570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM723_RS01575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM723_RS01595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM723_RS01600	COG1464	Belongs to the NlpA lipoprotein family
IM723_RS01610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IM723_RS01635	COG1122	ATPase activity
IM723_RS01645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IM723_RS01655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM723_RS01670	COG0745	RESPONSE REGULATOR receiver
IM723_RS01675	COG5002	protein histidine kinase activity
IM723_RS01690	COG1484	DNA-dependent DNA replication
IM723_RS01715	COG3328	transposase activity
IM723_RS01730	COG3716	PTS system mannose fructose sorbose family IID component
IM723_RS01735	COG3715	PTS system
IM723_RS01745	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IM723_RS01750	COG0561	phosphatase activity
IM723_RS01755	COG2252	PERMEase
IM723_RS01760	COG0802	atpase or kinase
IM723_RS01765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM723_RS01770	COG1316	TRANSCRIPTIONal
IM723_RS01780	COG0195	Participates in both transcription termination and antitermination
IM723_RS01785	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IM723_RS01820	COG2244	polysaccharide biosynthetic process
IM723_RS01825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM723_RS01830	COG0626	cystathionine gamma-synthase activity
IM723_RS01835	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IM723_RS01865	COG4471	UPF0298 protein
IM723_RS01875	COG0559	Belongs to the binding-protein-dependent transport system permease family
IM723_RS01905	COG1739	Uncharacterized protein family UPF0029
IM723_RS01910	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IM723_RS01915	COG1040	competence protein
IM723_RS02000	COG2502	aspartate--ammonia ligase
IM723_RS02005	COG0527	aspartate kinase activity
IM723_RS02010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM723_RS02015	COG1024	Enoyl-CoA hydratase
IM723_RS02020	COG1846	Transcriptional regulator
IM723_RS02040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IM723_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
IM723_RS02050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM723_RS02065	COG0439	Biotin carboxylase
IM723_RS02095	COG0076	glutamate decarboxylase activity
IM723_RS02100	COG0531	amino acid
IM723_RS02125	COG1349	DNA-binding transcription factor activity
IM723_RS02130	COG1105	Belongs to the carbohydrate kinase PfkB family
IM723_RS02140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM723_RS02145	COG0285	dihydrofolate synthase activity
IM723_RS02155	COG1104	cysteine desulfurase activity
IM723_RS02220	COG0488	(ABC) transporter
IM723_RS02240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IM723_RS02245	COG0242	peptide deformylase activity
IM723_RS02305	COG1702	phosphate starvation-inducible protein PhoH
IM723_RS02330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM723_RS02330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM723_RS02350	COG4122	O-methyltransferase activity
IM723_RS02355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM723_RS02395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM723_RS02400	COG0436	Aminotransferase
IM723_RS02410	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IM723_RS02415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM723_RS02420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM723_RS02425	COG0726	polysaccharide deacetylase
IM723_RS02440	COG2962	Rard protein
IM723_RS02475	COG0356	it plays a direct role in the translocation of protons across the membrane
IM723_RS02510	COG0772	Belongs to the SEDS family
IM723_RS02530	COG0470	DNA polymerase III
IM723_RS02535	COG1774	PSP1 C-terminal conserved region
IM723_RS02540	COG4467	Involved in initiation control of chromosome replication
IM723_RS02550	COG0004	ammonium transporteR
IM723_RS02555	COG0347	Belongs to the P(II) protein family
IM723_RS02560	COG1388	LysM domain
IM723_RS02560	COG1705	Flagellar rod assembly protein muramidase FlgJ
IM723_RS02605	COG1113	amino acid transport
IM723_RS02620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM723_RS02645	COG0583	DNA-binding transcription factor activity
IM723_RS02655	COG0564	pseudouridine synthase activity
IM723_RS02675	COG0505	Belongs to the CarA family
IM723_RS02700	COG0577	efflux transmembrane transporter activity
IM723_RS02705	COG0577	efflux transmembrane transporter activity
IM723_RS02730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IM723_RS02745	COG3279	Response regulator of the LytR AlgR family
IM723_RS02755	COG1131	(ABC) transporter
IM723_RS02790	COG1187	pseudouridine synthase activity
IM723_RS02795	COG1473	amidohydrolase
IM723_RS02800	COG0686	Belongs to the AlaDH PNT family
IM723_RS02805	COG0686	Belongs to the AlaDH PNT family
IM723_RS02810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM723_RS02875	COG0438	transferase activity, transferring glycosyl groups
IM723_RS02910	COG1272	protein, Hemolysin III
IM723_RS02925	COG3425	synthase
IM723_RS02935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IM723_RS02955	COG0833	amino acid
IM723_RS02960	COG2040	homocysteine
IM723_RS02980	COG0187	DNA topoisomerase II activity
IM723_RS02990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM723_RS03010	COG0539	negative regulation of cytoplasmic translation
IM723_RS03050	COG0494	nUDIX hydrolase
IM723_RS03055	COG0542	response to heat
IM723_RS03060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM723_RS03065	COG4703	Protein of unknown function (DUF1797)
IM723_RS03070	COG0765	amino acid transport
IM723_RS03105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM723_RS03110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IM723_RS03115	COG0768	penicillin binding
IM723_RS03120	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IM723_RS03135	COG3711	transcriptional antiterminator
IM723_RS03145	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IM723_RS03150	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IM723_RS03155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM723_RS03160	COG0237	dephospho-CoA kinase activity
IM723_RS03165	COG2814	Major facilitator Superfamily
IM723_RS03180	COG0557	exoribonuclease II activity
IM723_RS03195	COG1185	polyribonucleotide nucleotidyltransferase activity
IM723_RS03200	COG0006	proline dipeptidase activity
IM723_RS03205	COG1609	Transcriptional regulator
IM723_RS03240	COG1368	sulfuric ester hydrolase activity
IM723_RS03245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM723_RS03270	COG0287	Prephenate dehydrogenase
IM723_RS03295	COG0077	Prephenate dehydratase
IM723_RS03335	COG0270	DNA (cytosine-5-)-methyltransferase activity
IM723_RS03415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM723_RS03435	COG3328	transposase activity
IM723_RS03440	COG0535	radical SAM domain protein
IM723_RS03445	COG1994	Peptidase M50
IM723_RS03455	COG1131	(ABC) transporter
IM723_RS03525	COG3843	relaxase mobilization nuclease domain protein
IM723_RS03550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM723_RS03555	COG2274	protein secretion by the type I secretion system
IM723_RS03655	COG1518	maintenance of DNA repeat elements
IM723_RS03660	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IM723_RS03670	COG3689	TIGRFAM TIGR03943 family protein
IM723_RS03675	COG0701	Predicted permease
IM723_RS03680	COG2183	response to ionizing radiation
IM723_RS03700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM723_RS03725	COG0826	peptidase U32
IM723_RS03735	COG1268	BioY protein
IM723_RS03745	COG4443	Transcriptional Coactivator p15 (PC4)
IM723_RS03750	COG1914	H( )-stimulated, divalent metal cation uptake system
IM723_RS03760	COG0494	nUDIX hydrolase
IM723_RS03790	COG0406	alpha-ribazole phosphatase activity
IM723_RS03795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IM723_RS03835	COG4221	oxidoreductase activity
IM723_RS03845	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IM723_RS03855	COG0732	type I restriction modification DNA specificity domain
IM723_RS03880	COG1704	LemA family
IM723_RS03885	COG0501	Belongs to the peptidase M48B family
IM723_RS03910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IM723_RS03920	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IM723_RS03925	COG0783	Belongs to the Dps family
IM723_RS03930	COG0735	belongs to the Fur family
IM723_RS03935	COG4483	Protein conserved in bacteria
IM723_RS03940	COG1940	carbohydrate kinase activity
IM723_RS03945	COG1217	gtp-binding protein TYPA
IM723_RS03975	COG0849	cell division
IM723_RS03985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IM723_RS04010	COG3599	regulation of cell shape
IM723_RS04040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IM723_RS04050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM723_RS04055	COG1435	thymidine kinase activity
IM723_RS04065	COG2890	protein-(glutamine-N5) methyltransferase activity
IM723_RS04095	COG1132	(ABC) transporter
IM723_RS04110	COG1696	Membrane protein involved in D-alanine export
IM723_RS04120	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IM723_RS04130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM723_RS04135	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM723_RS04195	COG1396	sequence-specific DNA binding
IM723_RS04200	COG0582	viral genome integration into host DNA
IM723_RS04220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM723_RS04225	COG4684	Psort location CytoplasmicMembrane, score
IM723_RS04230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IM723_RS04255	COG5002	protein histidine kinase activity
IM723_RS04280	COG2813	Specifically methylates the guanine in position
IM723_RS04295	COG0295	cytidine deaminase activity
IM723_RS04300	COG1744	ABC transporter substrate-binding protein PnrA-like
IM723_RS04305	COG3845	ABC transporter
IM723_RS04310	COG4603	Belongs to the binding-protein-dependent transport system permease family
IM723_RS04315	COG1079	Belongs to the binding-protein-dependent transport system permease family
IM723_RS04325	COG1199	ATP-dependent helicase activity
IM723_RS04325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM723_RS04335	COG0436	Aminotransferase
IM723_RS04350	COG0251	oxidation-reduction process
IM723_RS04360	COG0720	synthase
IM723_RS04410	COG1278	Cold shock
IM723_RS04420	COG3328	transposase activity
IM723_RS04425	COG2217	Heavy metal translocating P-type atpase
IM723_RS04430	COG3328	transposase activity
IM723_RS04440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM723_RS04445	COG0626	cystathionine gamma-synthase activity
IM723_RS04450	COG1045	serine acetyltransferase
IM723_RS04465	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IM723_RS04475	COG4975	Glucose uptake
IM723_RS04495	COG3443	Belongs to the bacterial solute-binding protein 9 family
IM723_RS04495	COG0803	Belongs to the bacterial solute-binding protein 9 family
IM723_RS04510	COG3942	CHAP domain
IM723_RS04510	COG1705	Flagellar rod assembly protein muramidase FlgJ
IM723_RS04525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM723_RS04530	COG2824	Alkylphosphonate utilization operon protein PhnA
IM723_RS04535	COG0765	amino acid transport
IM723_RS04540	COG1126	abc transporter atp-binding protein
IM723_RS04545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM723_RS04565	COG1064	alcohol dehydrogenase
IM723_RS04570	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IM723_RS04580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IM723_RS04580	COG0519	Catalyzes the synthesis of GMP from XMP
IM723_RS04585	COG2188	Transcriptional regulator
IM723_RS04595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IM723_RS04605	COG1827	regulation of RNA biosynthetic process
IM723_RS04615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IM723_RS04625	COG1940	carbohydrate kinase activity
IM723_RS04630	COG0758	DNA mediated transformation
IM723_RS04635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM723_RS04685	COG0481	GTPase activity
IM723_RS04700	COG0028	Belongs to the TPP enzyme family
IM723_RS04705	COG3527	Alpha-acetolactate decarboxylase
IM723_RS04725	COG1230	cation diffusion facilitator family transporter
IM723_RS04735	COG1063	alcohol dehydrogenase
IM723_RS04775	COG1293	RNA-binding protein homologous to eukaryotic snRNP
IM723_RS04785	COG0047	phosphoribosylformylglycinamidine synthase activity
IM723_RS04800	COG0167	dihydroorotate dehydrogenase activity
IM723_RS04805	COG1518	maintenance of DNA repeat elements
IM723_RS04805	COG1468	defense response to virus
IM723_RS04810	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IM723_RS04830	COG1337	RAMP superfamily
IM723_RS04835	COG1567	CRISPR-associated RAMP protein, Csm4 family
IM723_RS04850	COG0284	orotidine-5'-phosphate decarboxylase activity
IM723_RS04865	COG3104	oligopeptide transport
IM723_RS04870	COG0154	amidase activity
IM723_RS04910	COG1115	amino acid carrier protein
IM723_RS04920	COG2873	o-acetylhomoserine
IM723_RS04950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IM723_RS04955	COG0196	riboflavin kinase activity
IM723_RS04960	COG1393	Belongs to the ArsC family
IM723_RS04970	COG0483	inositol monophosphate 1-phosphatase activity
IM723_RS04975	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IM723_RS04975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IM723_RS04985	COG0573	inorganic phosphate transmembrane transporter activity
IM723_RS04990	COG0581	inorganic phosphate transmembrane transporter activity
IM723_RS05005	COG0704	Plays a role in the regulation of phosphate uptake
IM723_RS05020	COG0095	Lipoate-protein ligase
IM723_RS05030	COG0058	SHG alpha-glucan phosphorylase activity
IM723_RS05035	COG1640	4-alpha-glucanotransferase
IM723_RS05065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM723_RS05070	COG0805	protein transport
IM723_RS05075	COG0672	)-iron permease
IM723_RS05080	COG2837	iron assimilation
IM723_RS05085	COG2822	iron ion transport
IM723_RS05090	COG4607	ABC-type enterochelin transport system periplasmic component
IM723_RS05095	COG4604	ABC transporter, ATP-binding protein
IM723_RS05100	COG4605	iron ion homeostasis
IM723_RS05105	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM723_RS05145	COG3328	transposase activity
IM723_RS05195	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM723_RS05200	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM723_RS05200	COG0022	dehydrogenase e1 component
IM723_RS05205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IM723_RS05230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IM723_RS05240	COG4667	esterase of the alpha-beta hydrolase superfamily
IM723_RS05265	COG0628	permease
IM723_RS05275	COG0561	phosphatase activity
IM723_RS05320	COG0438	transferase activity, transferring glycosyl groups
IM723_RS05330	COG1442	glycosyl transferase family 8
IM723_RS05330	COG1216	Glycosyl transferase, family 2
IM723_RS05370	COG1316	TRANSCRIPTIONal
IM723_RS05390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IM723_RS05400	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IM723_RS05425	COG1573	uracil-dna glycosylase
IM723_RS05460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IM723_RS05490	COG0681	Belongs to the peptidase S26 family
IM723_RS05500	COG0628	permease
IM723_RS05505	COG1051	belongs to the nudix hydrolase family
IM723_RS05510	COG2177	Part of the ABC transporter FtsEX involved in
IM723_RS05515	COG2884	Cell division ATP-binding protein ftsE
IM723_RS05525	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IM723_RS05560	COG2348	transferase activity, transferring amino-acyl groups
IM723_RS05570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IM723_RS05575	COG5002	protein histidine kinase activity
IM723_RS05580	COG0745	RESPONSE REGULATOR receiver
IM723_RS05585	COG1126	abc transporter atp-binding protein
IM723_RS05590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM723_RS05595	COG0765	amino acid transport
IM723_RS05600	COG0765	amino acid transport
IM723_RS05625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IM723_RS05635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IM723_RS05640	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IM723_RS05640	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IM723_RS05650	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IM723_RS05655	COG1956	GAF domain-containing protein
IM723_RS05660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IM723_RS05680	COG0335	large ribosomal subunit rRNA binding
IM723_RS05685	COG0038	chloride channel
IM723_RS05695	COG0038	chloride channel
IM723_RS05700	COG0716	FMN binding
IM723_RS05760	COG0469	pyruvate kinase activity
IM723_RS05810	COG0167	dihydroorotate dehydrogenase activity
IM723_RS05820	COG0776	regulation of translation
IM723_RS05830	COG2755	lipolytic protein G-D-S-L family
IM723_RS05835	COG1307	EDD domain protein, DegV family
IM723_RS05840	COG0497	DNA recombination
IM723_RS05845	COG1438	arginine binding
IM723_RS05850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IM723_RS05875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IM723_RS05895	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IM723_RS05895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IM723_RS05900	COG0300	oxidoreductase activity
IM723_RS05915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM723_RS05920	COG0772	Belongs to the SEDS family
IM723_RS05935	COG0107	imidazoleglycerol-phosphate synthase activity
IM723_RS05945	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IM723_RS05955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IM723_RS06005	COG0647	UMP catabolic process
IM723_RS06015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM723_RS06045	COG1088	dTDP-glucose 4,6-dehydratase activity
IM723_RS06055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IM723_RS06060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM723_RS06075	COG2384	SAM-dependent methyltransferase
IM723_RS06100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IM723_RS06105	COG3442	glutamine amidotransferase
IM723_RS06110	COG0392	lysyltransferase activity
IM723_RS06110	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IM723_RS06125	COG0488	(ABC) transporter
IM723_RS06135	COG0513	Belongs to the DEAD box helicase family
IM723_RS06165	COG0372	Belongs to the citrate synthase family
IM723_RS06170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IM723_RS06175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IM723_RS06180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM723_RS06185	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM723_RS06215	COG3764	Sortase (surface protein transpeptidase)
IM723_RS06235	COG0488	(ABC) transporter
IM723_RS06260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM723_RS06265	COG1328	CTP reductase activity
IM723_RS06265	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IM723_RS06290	COG1196	nuclear chromosome segregation
IM723_RS06305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IM723_RS06320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM723_RS06330	COG1011	Hydrolase
IM723_RS06335	COG1268	BioY protein
IM723_RS06345	COG0517	IMP dehydrogenase activity
IM723_RS06345	COG1125	glycine betaine transport
IM723_RS06360	COG2986	histidine ammonia-lyase
IM723_RS06370	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IM723_RS06375	COG1760	l-serine dehydratase
IM723_RS06380	COG1760	l-serine dehydratase
IM723_RS06405	COG2197	response regulator
IM723_RS06410	COG4585	Histidine kinase
IM723_RS06420	COG1131	(ABC) transporter
IM723_RS06450	COG3328	transposase activity
IM723_RS06500	COG0577	efflux transmembrane transporter activity
IM723_RS06505	COG1136	(ABC) transporter
IM723_RS06510	COG0784	Response regulator, receiver
IM723_RS06510	COG2198	Histidine kinase
IM723_RS06510	COG5002	protein histidine kinase activity
IM723_RS06515	COG0745	RESPONSE REGULATOR receiver
IM723_RS06530	COG0534	Mate efflux family protein
IM723_RS06535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM723_RS06535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM723_RS06550	COG1126	abc transporter atp-binding protein
IM723_RS06555	COG0765	amino acid transport
IM723_RS06565	COG2079	MmgE PrpD family protein
IM723_RS06570	COG0436	Aminotransferase
IM723_RS06580	COG1473	amidohydrolase
IM723_RS06600	COG0531	amino acid
IM723_RS06615	COG1959	2 iron, 2 sulfur cluster binding
IM723_RS06625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IM723_RS06630	COG0778	Nitroreductase
IM723_RS06640	COG0656	L-ascorbic acid biosynthetic process
IM723_RS06690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM723_RS06710	COG1280	lysine exporter protein (LysE YggA)
IM723_RS06720	COG1216	Glycosyl transferase, family 2
IM723_RS06720	COG1442	glycosyl transferase family 8
IM723_RS06725	COG0577	efflux transmembrane transporter activity
IM723_RS06780	COG1396	sequence-specific DNA binding
IM723_RS06800	COG0419	ATPase involved in DNA repair
IM723_RS06805	COG0420	3'-5' exonuclease activity
IM723_RS06815	COG3250	beta-galactosidase activity
IM723_RS06820	COG2211	Major facilitator Superfamily
IM723_RS06820	COG2190	(PTS) system
IM723_RS06825	COG2017	converts alpha-aldose to the beta-anomer
IM723_RS06830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IM723_RS06845	COG1609	Transcriptional regulator
IM723_RS06865	COG0488	(ABC) transporter
IM723_RS06915	COG2197	response regulator
IM723_RS06920	COG4585	Histidine kinase
IM723_RS06935	COG0515	serine threonine protein kinase
IM723_RS06935	COG2815	serine threonine protein kinase
IM723_RS06945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IM723_RS06945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM723_RS06955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IM723_RS06970	COG0552	protein localization to endoplasmic reticulum
IM723_RS06975	COG0561	phosphatase activity
IM723_RS06980	COG0561	phosphatase activity
IM723_RS06985	COG1725	Transcriptional regulator
IM723_RS06990	COG1131	(ABC) transporter
IM723_RS07000	COG4608	Belongs to the ABC transporter superfamily
IM723_RS07005	COG0444	Belongs to the ABC transporter superfamily
IM723_RS07010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM723_RS07015	COG0601	transmembrane transport
IM723_RS07020	COG4166	transmembrane transport
IM723_RS07030	COG4166	transmembrane transport
IM723_RS07050	COG2223	nitrite transmembrane transporter activity
IM723_RS07060	COG0280	phosphate acetyltransferase
IM723_RS07065	COG0564	pseudouridine synthase activity
IM723_RS07075	COG2357	RelA SpoT domain protein
IM723_RS07090	COG1104	cysteine desulfurase activity
IM723_RS07105	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IM723_RS07110	COG2003	Belongs to the UPF0758 family
IM723_RS07135	COG1215	transferase activity, transferring glycosyl groups
IM723_RS07145	COG1442	glycosyl transferase family 8
IM723_RS07145	COG1216	Glycosyl transferase, family 2
IM723_RS07165	COG1091	dTDP-4-dehydrorhamnose reductase activity
IM723_RS07175	COG0463	Glycosyl transferase, family 2
IM723_RS07185	COG2151	metal-sulfur cluster biosynthetic enzyme
IM723_RS07190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IM723_RS07195	COG0358	DNA primase activity
IM723_RS07200	COG1970	mechanosensitive ion channel activity
IM723_RS07210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM723_RS07215	COG0436	Aminotransferase
IM723_RS07220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM723_RS07225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM723_RS07230	COG1051	belongs to the nudix hydrolase family
IM723_RS07250	COG0765	amino acid transport
IM723_RS07255	COG1126	abc transporter atp-binding protein
IM723_RS07275	COG1187	pseudouridine synthase activity
IM723_RS07320	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IM723_RS07325	COG1518	maintenance of DNA repeat elements
IM723_RS07335	COG0560	Phosphoserine phosphatase
IM723_RS07345	COG0187	DNA topoisomerase II activity
IM723_RS07355	COG1346	cytolysis
IM723_RS07360	COG1380	Effector of murein hydrolase LrgA
IM723_RS07370	COG1393	Belongs to the ArsC family
IM723_RS07380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM723_RS07415	COG1177	transmembrane transport
IM723_RS07420	COG1176	ABC-type spermidine putrescine transport system, permease component I
IM723_RS07460	COG0531	amino acid
IM723_RS07465	COG0285	dihydrofolate synthase activity
IM723_RS07470	COG1837	Belongs to the UPF0109 family
IM723_RS07490	COG0708	Exodeoxyribonuclease III
IM723_RS07505	COG1597	lipid kinase activity
IM723_RS07515	COG4708	membrane
IM723_RS07525	COG0024	Methionine aminopeptidase
IM723_RS07530	COG4109	DRTGG domain
IM723_RS07540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM723_RS07545	COG2333	competence protein COMEC
IM723_RS07545	COG0658	competence protein
IM723_RS07550	COG1555	photosystem II stabilization
IM723_RS07550	COG1596	polysaccharide export
IM723_RS07555	COG0204	Acyl-transferase
IM723_RS07565	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IM723_RS07575	COG0513	Belongs to the DEAD box helicase family
IM723_RS07595	COG1396	sequence-specific DNA binding
IM723_RS07600	COG2211	Major facilitator Superfamily
IM723_RS07615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IM723_RS07630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM723_RS07635	COG1126	abc transporter atp-binding protein
IM723_RS07640	COG0765	amino acid transport
IM723_RS07645	COG0765	amino acid transport
IM723_RS07650	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM723_RS07660	COG2217	Heavy metal translocating P-type atpase
IM723_RS07680	COG0135	phosphoribosylanthranilate isomerase activity
IM723_RS07695	COG0512	Glutamine amidotransferase of anthranilate synthase
IM723_RS07700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM723_RS07705	COG1605	Chorismate mutase
IM723_RS07705	COG0287	Prephenate dehydrogenase
IM723_RS07715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM723_RS07740	COG2176	DNA-directed DNA polymerase activity
IM723_RS07750	COG2151	metal-sulfur cluster biosynthetic enzyme
IM723_RS07760	COG2081	HI0933 family
IM723_RS07785	COG1131	(ABC) transporter
IM723_RS07790	COG0537	adenosine 5'-monophosphoramidase activity
IM723_RS07825	COG2226	methyltransferase
IM723_RS07830	COG0799	negative regulation of ribosome biogenesis
IM723_RS07835	COG1713	HD superfamily hydrolase involved in NAD metabolism
IM723_RS07840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IM723_RS07845	COG1534	Rna-binding protein
IM723_RS07850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IM723_RS07855	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IM723_RS07910	COG1335	isochorismatase
IM723_RS07920	COG0436	Aminotransferase
IM723_RS07925	COG0589	response to stress
IM723_RS07945	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IM723_RS07955	COG1253	flavin adenine dinucleotide binding
IM723_RS07960	COG1119	ATPase activity
IM723_RS07965	COG0025	NhaP-type Na H and K H
IM723_RS07975	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IM723_RS07980	COG1242	4 iron, 4 sulfur cluster binding
IM723_RS07985	COG3480	Lon protease (S16) C-terminal proteolytic domain
IM723_RS07990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IM723_RS07995	COG0742	ribosomal rna small subunit methyltransferase
IM723_RS08000	COG0492	ferredoxin-NADP+ reductase activity
IM723_RS08010	COG1126	abc transporter atp-binding protein
IM723_RS08020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM723_RS08035	COG1882	Formate acetyltransferase
IM723_RS08070	COG0390	transport system, permease component
IM723_RS08075	COG4619	ABC transporter
IM723_RS08080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM723_RS08095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IM723_RS08100	COG2936	dipeptidyl-peptidase activity
IM723_RS08155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM723_RS08165	COG1132	(ABC) transporter
IM723_RS08170	COG1132	(ABC) transporter
IM723_RS08185	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IM723_RS08190	COG4470	Protein conserved in bacteria
IM723_RS08195	COG0737	Belongs to the 5'-nucleotidase family
IM723_RS08205	COG0513	Belongs to the DEAD box helicase family
IM723_RS08215	COG0768	penicillin binding
IM723_RS08240	COG3152	Membrane
IM723_RS08250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IM723_RS08275	COG1074	ATP-dependent DNA helicase activity
IM723_RS08280	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IM723_RS08310	COG0561	phosphatase activity
IM723_RS08315	COG0252	asparaginase activity
IM723_RS08320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IM723_RS08325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IM723_RS08335	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM723_RS08340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM723_RS08345	COG0653	protein targeting
IM723_RS08355	COG1482	cell wall glycoprotein biosynthetic process
IM723_RS08360	COG1940	carbohydrate kinase activity
IM723_RS08365	COG1263	PTS System
IM723_RS08365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM723_RS08365	COG2190	(PTS) system
IM723_RS08370	COG1621	beta-fructofuranosidase activity
IM723_RS08375	COG1609	Transcriptional regulator
IM723_RS08395	COG2131	deaminase
IM723_RS08400	COG0006	proline dipeptidase activity
IM723_RS08410	COG1131	(ABC) transporter
IM723_RS08415	COG1131	(ABC) transporter
IM723_RS08490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM723_RS08490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM723_RS08495	COG1193	negative regulation of DNA recombination
IM723_RS08515	COG0681	Belongs to the peptidase S26 family
IM723_RS08520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IM723_RS08530	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IM723_RS08540	COG0456	acetyltransferase
IM723_RS08545	COG1214	PFAM Peptidase M22, glycoprotease
IM723_RS08565	COG0174	glutamine synthetase
IM723_RS08570	COG0789	Transcriptional regulator
IM723_RS08620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM723_RS08655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM723_RS08665	COG0084	hydrolase, TatD family'
IM723_RS08670	COG1832	CoA-binding protein
IM723_RS08675	COG3118	belongs to the thioredoxin family
IM723_RS08740	COG0706	membrane insertase activity
IM723_RS08800	COG0756	dUTP diphosphatase activity
IM723_RS08830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IM723_RS08835	COG0705	Rhomboid family
IM723_RS08835	COG0457	Tetratricopeptide repeat
IM723_RS08840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IM723_RS08860	COG2226	methyltransferase
IM723_RS08885	COG0425	Belongs to the sulfur carrier protein TusA family
IM723_RS08890	COG2391	methyltransferase activity
IM723_RS08895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM723_RS08900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM723_RS08910	COG1363	Peptidase, m42
IM723_RS08915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IM723_RS08920	COG1266	CAAX protease self-immunity
IM723_RS08975	COG1459	type II secretion system
IM723_RS08980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM723_RS09015	COG0440	acetolactate synthase activity
IM723_RS09020	COG0028	Belongs to the TPP enzyme family
IM723_RS09025	COG0129	dihydroxy-acid dehydratase activity
IM723_RS09030	COG1461	Dihydroxyacetone kinase
IM723_RS09040	COG0534	Mate efflux family protein
IM723_RS09055	COG1012	belongs to the aldehyde dehydrogenase family
IM723_RS09055	COG1454	alcohol dehydrogenase
IM723_RS09060	COG1454	alcohol dehydrogenase
IM723_RS09060	COG1012	belongs to the aldehyde dehydrogenase family
IM723_RS09065	COG1012	belongs to the aldehyde dehydrogenase family
IM723_RS09065	COG1454	alcohol dehydrogenase
IM723_RS09075	COG1012	belongs to the aldehyde dehydrogenase family
IM723_RS09075	COG1454	alcohol dehydrogenase
IM723_RS09080	COG3590	peptidase
IM723_RS09085	COG0366	Alpha amylase catalytic
IM723_RS09090	COG0366	Alpha amylase catalytic
IM723_RS09095	COG0366	Alpha amylase catalytic
IM723_RS09105	COG1609	Transcriptional regulator
IM723_RS09110	COG2188	Transcriptional regulator
IM723_RS09115	COG4475	Protein of unknown function (DUF436)
IM723_RS09135	COG0191	fructose-bisphosphate aldolase activity
IM723_RS09195	COG0201	protein transport
IM723_RS09300	COG0051	transcription antitermination factor activity, RNA binding
IM723_RS09340	COG3328	transposase activity
IM723_RS09350	COG0515	serine threonine protein kinase
IM723_RS09355	COG1132	(ABC) transporter
IM723_RS09370	COG1132	(ABC) transporter
IM723_RS09400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IM723_RS09430	COG1328	CTP reductase activity
IM723_RS09440	COG0602	queuosine metabolic process
IM723_RS09445	COG3022	response to hydroperoxide
IM723_RS09450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM723_RS09470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM723_RS09485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IM723_RS09510	COG3328	transposase activity
IM723_RS09515	COG2261	transglycosylase associated protein
IM723_RS09535	COG3237	CsbD-like
IM723_RS09565	COG1511	domain protein
IM723_RS09565	COG1511	domain protein
IM723_RS09575	COG3759	membrane
IM723_RS09595	COG0305	Participates in initiation and elongation during chromosome replication
IM723_RS09630	COG0741	lytic transglycosylase activity
IM723_RS09635	COG1388	LysM domain
IM723_RS09635	COG3584	3D domain protein
IM723_RS09640	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IM723_RS09655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IM723_RS09665	COG0612	Peptidase, M16
IM723_RS09695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM723_RS09700	COG0488	(ABC) transporter
IM723_RS09735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM723_RS09740	COG1475	DNA binding