locus-tag	class	description
CR922_RS00010	COG0592	DNA-directed DNA polymerase activity
CR922_RS00020	COG0012	GTP binding
CR922_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CR922_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CR922_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CR922_RS00195	COG3942	CHAP domain
CR922_RS00210	COG0436	Aminotransferase
CR922_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CR922_RS00235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CR922_RS00250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CR922_RS00270	COG0151	Belongs to the GarS family
CR922_RS00275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CR922_RS00295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CR922_RS00310	COG4550	Control of competence regulator ComK, YlbF/YmcA
CR922_RS00365	COG1393	Belongs to the ArsC family
CR922_RS00455	COG2309	aminopeptidase activity
CR922_RS00470	COG0431	NADPH-dependent FMN reductase
CR922_RS00510	COG4463	regulation of RNA biosynthetic process
CR922_RS00515	COG0542	response to heat
CR922_RS00525	COG1686	Belongs to the peptidase S11 family
CR922_RS00540	COG1045	serine acetyltransferase
CR922_RS00550	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CR922_RS00560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CR922_RS00585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CR922_RS00595	COG0582	viral genome integration into host DNA
CR922_RS00735	COG3830	Belongs to the UPF0237 family
CR922_RS00745	COG0588	phosphoglycerate mutase activity
CR922_RS00750	COG1876	peptidase activity
CR922_RS00785	COG0351	phosphomethylpyrimidine kinase
CR922_RS00895	COG3118	belongs to the thioredoxin family
CR922_RS00900	COG1832	CoA-binding protein
CR922_RS00905	COG0084	hydrolase, TatD family'
CR922_RS00950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CR922_RS01000	COG0789	Transcriptional regulator
CR922_RS01005	COG0174	glutamine synthetase
CR922_RS01025	COG1214	PFAM Peptidase M22, glycoprotease
CR922_RS01030	COG0456	acetyltransferase
CR922_RS01040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CR922_RS01050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CR922_RS01055	COG0681	Belongs to the peptidase S26 family
CR922_RS01080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR922_RS01080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CR922_RS01170	COG0006	proline dipeptidase activity
CR922_RS01175	COG2131	deaminase
CR922_RS01200	COG1621	beta-fructofuranosidase activity
CR922_RS01205	COG1263	PTS System
CR922_RS01205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR922_RS01205	COG2190	(PTS) system
CR922_RS01210	COG1940	carbohydrate kinase activity
CR922_RS01215	COG1482	cell wall glycoprotein biosynthetic process
CR922_RS01230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CR922_RS01235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CR922_RS01250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CR922_RS01255	COG0252	asparaginase activity
CR922_RS01260	COG0561	phosphatase activity
CR922_RS01290	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CR922_RS01330	COG3152	Membrane
CR922_RS01365	COG0768	penicillin binding
CR922_RS01375	COG0513	Belongs to the DEAD box helicase family
CR922_RS01385	COG4470	Protein conserved in bacteria
CR922_RS01405	COG1132	(ABC) transporter
CR922_RS01410	COG1132	(ABC) transporter
CR922_RS01470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CR922_RS01495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CR922_RS01505	COG4619	ABC transporter
CR922_RS01510	COG0390	transport system, permease component
CR922_RS01555	COG1882	Formate acetyltransferase
CR922_RS01570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR922_RS01580	COG1126	abc transporter atp-binding protein
CR922_RS01590	COG0492	ferredoxin-NADP+ reductase activity
CR922_RS01595	COG0742	ribosomal rna small subunit methyltransferase
CR922_RS01600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CR922_RS01605	COG3480	Lon protease (S16) C-terminal proteolytic domain
CR922_RS01610	COG1242	4 iron, 4 sulfur cluster binding
CR922_RS01615	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CR922_RS01625	COG0025	NhaP-type Na H and K H
CR922_RS01630	COG1119	ATPase activity
CR922_RS01635	COG1253	flavin adenine dinucleotide binding
CR922_RS01645	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CR922_RS01660	COG0589	response to stress
CR922_RS01665	COG0436	Aminotransferase
CR922_RS01675	COG1335	isochorismatase
CR922_RS01730	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CR922_RS01735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CR922_RS01740	COG1534	Rna-binding protein
CR922_RS01745	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CR922_RS01750	COG1713	HD superfamily hydrolase involved in NAD metabolism
CR922_RS01755	COG0799	negative regulation of ribosome biogenesis
CR922_RS01765	COG2226	methyltransferase
CR922_RS01795	COG0537	adenosine 5'-monophosphoramidase activity
CR922_RS01800	COG1131	(ABC) transporter
CR922_RS01825	COG2081	HI0933 family
CR922_RS01835	COG2151	metal-sulfur cluster biosynthetic enzyme
CR922_RS01845	COG2176	DNA-directed DNA polymerase activity
CR922_RS01870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CR922_RS01880	COG1605	Chorismate mutase
CR922_RS01880	COG0287	Prephenate dehydrogenase
CR922_RS01890	COG0512	Glutamine amidotransferase of anthranilate synthase
CR922_RS01905	COG0135	phosphoribosylanthranilate isomerase activity
CR922_RS01925	COG2217	Heavy metal translocating P-type atpase
CR922_RS01935	COG1181	Belongs to the D-alanine--D-alanine ligase family
CR922_RS01940	COG0765	amino acid transport
CR922_RS01945	COG0765	amino acid transport
CR922_RS01950	COG1126	abc transporter atp-binding protein
CR922_RS01955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR922_RS01970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CR922_RS01985	COG2211	Major facilitator Superfamily
CR922_RS01990	COG1396	sequence-specific DNA binding
CR922_RS02010	COG0513	Belongs to the DEAD box helicase family
CR922_RS02020	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CR922_RS02025	COG0726	polysaccharide deacetylase
CR922_RS02035	COG0204	Acyl-transferase
CR922_RS02040	COG1596	polysaccharide export
CR922_RS02040	COG1555	photosystem II stabilization
CR922_RS02045	COG2333	competence protein COMEC
CR922_RS02045	COG0658	competence protein
CR922_RS02060	COG4109	DRTGG domain
CR922_RS02065	COG0024	Methionine aminopeptidase
CR922_RS02075	COG4708	membrane
CR922_RS02085	COG1597	lipid kinase activity
CR922_RS02100	COG0708	Exodeoxyribonuclease III
CR922_RS02110	COG0500	methyltransferase
CR922_RS02110	COG3615	Tellurite resistance protein tehB
CR922_RS02120	COG1837	Belongs to the UPF0109 family
CR922_RS02125	COG0285	dihydrofolate synthase activity
CR922_RS02130	COG0531	amino acid
CR922_RS02170	COG1176	ABC-type spermidine putrescine transport system, permease component I
CR922_RS02175	COG1177	transmembrane transport
CR922_RS02210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CR922_RS02220	COG1393	Belongs to the ArsC family
CR922_RS02230	COG1380	Effector of murein hydrolase LrgA
CR922_RS02235	COG1346	cytolysis
CR922_RS02245	COG0187	DNA topoisomerase II activity
CR922_RS02255	COG0560	Phosphoserine phosphatase
CR922_RS02300	COG1132	(ABC) transporter
CR922_RS02335	COG1187	pseudouridine synthase activity
CR922_RS02355	COG1126	abc transporter atp-binding protein
CR922_RS02360	COG0765	amino acid transport
CR922_RS02380	COG1051	belongs to the nudix hydrolase family
CR922_RS02385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR922_RS02390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR922_RS02395	COG0436	Aminotransferase
CR922_RS02400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR922_RS02420	COG0358	DNA primase activity
CR922_RS02425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CR922_RS02430	COG2151	metal-sulfur cluster biosynthetic enzyme
CR922_RS02435	COG0463	Glycosyl transferase, family 2
CR922_RS02440	COG1091	dTDP-4-dehydrorhamnose reductase activity
CR922_RS02450	COG1216	Glycosyl transferase, family 2
CR922_RS02480	COG1215	transferase activity, transferring glycosyl groups
CR922_RS02515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CR922_RS02530	COG1104	cysteine desulfurase activity
CR922_RS02545	COG2357	RelA SpoT domain protein
CR922_RS02555	COG0564	pseudouridine synthase activity
CR922_RS02560	COG0280	phosphate acetyltransferase
CR922_RS02570	COG2223	nitrite transmembrane transporter activity
CR922_RS02575	COG0084	hydrolase, TatD family'
CR922_RS02580	COG4608	Belongs to the ABC transporter superfamily
CR922_RS02585	COG4608	Belongs to the ABC transporter superfamily
CR922_RS02595	COG4166	transmembrane transport
CR922_RS02605	COG4166	transmembrane transport
CR922_RS02610	COG0601	transmembrane transport
CR922_RS02615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CR922_RS02620	COG0444	Belongs to the ABC transporter superfamily
CR922_RS02625	COG4608	Belongs to the ABC transporter superfamily
CR922_RS02635	COG1131	(ABC) transporter
CR922_RS02640	COG1725	Transcriptional regulator
CR922_RS02645	COG0561	phosphatase activity
CR922_RS02650	COG0561	phosphatase activity
CR922_RS02655	COG0552	protein localization to endoplasmic reticulum
CR922_RS02670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CR922_RS02680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CR922_RS02680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CR922_RS02690	COG0515	serine threonine protein kinase
CR922_RS02690	COG2815	serine threonine protein kinase
CR922_RS02705	COG4585	Histidine kinase
CR922_RS02710	COG2197	response regulator
CR922_RS02765	COG0488	(ABC) transporter
CR922_RS02785	COG1609	Transcriptional regulator
CR922_RS02800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CR922_RS02805	COG2017	converts alpha-aldose to the beta-anomer
CR922_RS02810	COG2211	Major facilitator Superfamily
CR922_RS02810	COG2190	(PTS) system
CR922_RS02815	COG3250	beta-galactosidase activity
CR922_RS02825	COG0420	3'-5' exonuclease activity
CR922_RS02830	COG0419	ATPase involved in DNA repair
CR922_RS02860	COG1280	lysine exporter protein (LysE YggA)
CR922_RS02880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CR922_RS02930	COG0656	L-ascorbic acid biosynthetic process
CR922_RS02940	COG0778	Nitroreductase
CR922_RS02945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR922_RS02945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CR922_RS02955	COG1959	2 iron, 2 sulfur cluster binding
CR922_RS02970	COG0531	amino acid
CR922_RS03000	COG1473	amidohydrolase
CR922_RS03010	COG0371	Dehydrogenase
CR922_RS03020	COG0436	Aminotransferase
CR922_RS03025	COG2079	MmgE PrpD family protein
CR922_RS03035	COG0765	amino acid transport
CR922_RS03040	COG1126	abc transporter atp-binding protein
CR922_RS03055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CR922_RS03055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CR922_RS03060	COG0534	Mate efflux family protein
CR922_RS03080	COG0745	RESPONSE REGULATOR receiver
CR922_RS03085	COG2198	Histidine kinase
CR922_RS03085	COG0784	Response regulator, receiver
CR922_RS03085	COG5002	protein histidine kinase activity
CR922_RS03090	COG1136	(ABC) transporter
CR922_RS03095	COG0577	efflux transmembrane transporter activity
CR922_RS03115	COG0385	Bile acid
CR922_RS03130	COG1131	(ABC) transporter
CR922_RS03140	COG4585	Histidine kinase
CR922_RS03145	COG2197	response regulator
CR922_RS03150	COG1131	(ABC) transporter
CR922_RS03155	COG1131	(ABC) transporter
CR922_RS03160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CR922_RS03185	COG1760	l-serine dehydratase
CR922_RS03190	COG1760	l-serine dehydratase
CR922_RS03195	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CR922_RS03205	COG2986	histidine ammonia-lyase
CR922_RS03220	COG0517	IMP dehydrogenase activity
CR922_RS03220	COG1125	glycine betaine transport
CR922_RS03230	COG1268	BioY protein
CR922_RS03235	COG1011	Hydrolase
CR922_RS03245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CR922_RS03265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CR922_RS03280	COG1196	nuclear chromosome segregation
CR922_RS03315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CR922_RS03315	COG1328	CTP reductase activity
CR922_RS03320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CR922_RS03345	COG0488	(ABC) transporter
CR922_RS03395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR922_RS03400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CR922_RS03405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CR922_RS03410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CR922_RS03415	COG0372	Belongs to the citrate synthase family
CR922_RS03440	COG0513	Belongs to the DEAD box helicase family
CR922_RS03450	COG0488	(ABC) transporter
CR922_RS03465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CR922_RS03465	COG0392	lysyltransferase activity
CR922_RS03470	COG3442	glutamine amidotransferase
CR922_RS03475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CR922_RS03500	COG2384	SAM-dependent methyltransferase
CR922_RS03515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CR922_RS03520	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CR922_RS03530	COG1088	dTDP-glucose 4,6-dehydratase activity
CR922_RS03555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CR922_RS03565	COG0647	UMP catabolic process
CR922_RS03590	COG0772	Belongs to the SEDS family
CR922_RS03595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CR922_RS03610	COG0300	oxidoreductase activity
CR922_RS03615	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CR922_RS03615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CR922_RS03635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CR922_RS03660	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CR922_RS03665	COG1438	arginine binding
CR922_RS03670	COG0497	DNA recombination
CR922_RS03675	COG1307	EDD domain protein, DegV family
CR922_RS03680	COG2755	lipolytic protein G-D-S-L family
CR922_RS03690	COG0776	regulation of translation
CR922_RS03700	COG0167	dihydroorotate dehydrogenase activity
CR922_RS03755	COG0469	pyruvate kinase activity
CR922_RS03825	COG0716	FMN binding
CR922_RS03830	COG0038	chloride channel
CR922_RS03840	COG0038	chloride channel
CR922_RS03845	COG0335	large ribosomal subunit rRNA binding
CR922_RS03870	COG1956	GAF domain-containing protein
CR922_RS03875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CR922_RS03885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CR922_RS03885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CR922_RS03905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CR922_RS03930	COG0765	amino acid transport
CR922_RS03935	COG0765	amino acid transport
CR922_RS03940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR922_RS03945	COG1126	abc transporter atp-binding protein
CR922_RS03950	COG0745	RESPONSE REGULATOR receiver
CR922_RS03955	COG5002	protein histidine kinase activity
CR922_RS03960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CR922_RS03970	COG2348	transferase activity, transferring amino-acyl groups
CR922_RS04005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CR922_RS04015	COG2884	Cell division ATP-binding protein ftsE
CR922_RS04020	COG2177	Part of the ABC transporter FtsEX involved in
CR922_RS04025	COG1051	belongs to the nudix hydrolase family
CR922_RS04030	COG0628	permease
CR922_RS04040	COG0681	Belongs to the peptidase S26 family
CR922_RS04070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CR922_RS04105	COG1573	uracil-dna glycosylase
CR922_RS04125	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CR922_RS04135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CR922_RS04155	COG1316	TRANSCRIPTIONal
CR922_RS04175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CR922_RS04195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CR922_RS04200	COG1442	glycosyl transferase family 8
CR922_RS04200	COG1216	Glycosyl transferase, family 2
CR922_RS04215	COG5039	Polysaccharide pyruvyl transferase
CR922_RS04245	COG3328	transposase activity
CR922_RS04260	COG0628	permease
CR922_RS04275	COG2723	6-phospho-beta-galactosidase activity
CR922_RS04300	COG4667	esterase of the alpha-beta hydrolase superfamily
CR922_RS04340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CR922_RS04345	COG0022	dehydrogenase e1 component
CR922_RS04345	COG0508	dehydrogenase complex catalyzes the overall conversion of
CR922_RS04350	COG0508	dehydrogenase complex catalyzes the overall conversion of
CR922_RS04410	COG1523	belongs to the glycosyl hydrolase 13 family
CR922_RS04425	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CR922_RS04430	COG4605	iron ion homeostasis
CR922_RS04435	COG4604	ABC transporter, ATP-binding protein
CR922_RS04455	COG2837	iron assimilation
CR922_RS04460	COG0672	)-iron permease
CR922_RS04465	COG0805	protein transport
CR922_RS04470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CR922_RS04490	COG1609	Transcriptional regulator
CR922_RS04495	COG1640	4-alpha-glucanotransferase
CR922_RS04500	COG0058	SHG alpha-glucan phosphorylase activity
CR922_RS04515	COG0095	Lipoate-protein ligase
CR922_RS04530	COG0704	Plays a role in the regulation of phosphate uptake
CR922_RS04545	COG0581	inorganic phosphate transmembrane transporter activity
CR922_RS04550	COG0573	inorganic phosphate transmembrane transporter activity
CR922_RS04560	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CR922_RS04560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CR922_RS04565	COG0483	inositol monophosphate 1-phosphatase activity
CR922_RS04575	COG1393	Belongs to the ArsC family
CR922_RS04580	COG0196	riboflavin kinase activity
CR922_RS04620	COG2873	o-acetylhomoserine
CR922_RS04630	COG1115	amino acid carrier protein
CR922_RS04655	COG0737	Belongs to the 5'-nucleotidase family
CR922_RS04675	COG0154	amidase activity
CR922_RS04685	COG3104	oligopeptide transport
CR922_RS04715	COG1567	CRISPR-associated RAMP protein, Csm4 family
CR922_RS04720	COG1337	RAMP superfamily
CR922_RS04740	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CR922_RS04750	COG0167	dihydroorotate dehydrogenase activity
CR922_RS04765	COG0047	phosphoribosylformylglycinamidine synthase activity
CR922_RS04775	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CR922_RS04825	COG1063	alcohol dehydrogenase
CR922_RS04835	COG1230	cation diffusion facilitator family transporter
CR922_RS04865	COG3527	Alpha-acetolactate decarboxylase
CR922_RS04870	COG0028	Belongs to the TPP enzyme family
CR922_RS04880	COG0010	Belongs to the arginase family
CR922_RS04885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CR922_RS04895	COG1396	sequence-specific DNA binding
CR922_RS04930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR922_RS04935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CR922_RS04970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CR922_RS04975	COG0758	DNA mediated transformation
CR922_RS04980	COG1940	carbohydrate kinase activity
CR922_RS04990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CR922_RS05000	COG1827	regulation of RNA biosynthetic process
CR922_RS05010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CR922_RS05020	COG2188	Transcriptional regulator
CR922_RS05025	COG0519	Catalyzes the synthesis of GMP from XMP
CR922_RS05025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CR922_RS05030	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CR922_RS05035	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CR922_RS05040	COG3421	Type III restriction
CR922_RS05055	COG1064	alcohol dehydrogenase
CR922_RS05070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CR922_RS05080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR922_RS05085	COG1126	abc transporter atp-binding protein
CR922_RS05090	COG0765	amino acid transport
CR922_RS05095	COG2824	Alkylphosphonate utilization operon protein PhnA
CR922_RS05100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CR922_RS05115	COG3942	CHAP domain
CR922_RS05115	COG1705	Flagellar rod assembly protein muramidase FlgJ
CR922_RS05140	COG0803	Belongs to the bacterial solute-binding protein 9 family
CR922_RS05140	COG3443	Belongs to the bacterial solute-binding protein 9 family
CR922_RS05185	COG3328	transposase activity
CR922_RS05200	COG0626	cystathionine gamma-synthase activity
CR922_RS05205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CR922_RS05220	COG3328	transposase activity
CR922_RS05230	COG3328	transposase activity
CR922_RS05240	COG1278	Cold shock
CR922_RS05305	COG0720	synthase
CR922_RS05315	COG0251	oxidation-reduction process
CR922_RS05335	COG0436	Aminotransferase
CR922_RS05345	COG1199	ATP-dependent helicase activity
CR922_RS05345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CR922_RS05355	COG1079	Belongs to the binding-protein-dependent transport system permease family
CR922_RS05360	COG4603	Belongs to the binding-protein-dependent transport system permease family
CR922_RS05365	COG3845	ABC transporter
CR922_RS05370	COG1744	ABC transporter substrate-binding protein PnrA-like
CR922_RS05390	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CR922_RS05400	COG2813	Specifically methylates the guanine in position
CR922_RS05415	COG5002	protein histidine kinase activity
CR922_RS05420	COG5002	protein histidine kinase activity
CR922_RS05430	COG0745	RESPONSE REGULATOR receiver
CR922_RS05450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CR922_RS05455	COG4684	Psort location CytoplasmicMembrane, score
CR922_RS05460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CR922_RS05480	COG0582	viral genome integration into host DNA
CR922_RS05545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CR922_RS05550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CR922_RS05560	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CR922_RS05570	COG1696	Membrane protein involved in D-alanine export
CR922_RS05585	COG1132	(ABC) transporter
CR922_RS05615	COG2890	protein-(glutamine-N5) methyltransferase activity
CR922_RS05630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CR922_RS05635	COG0625	glutathione transferase activity
CR922_RS05640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CR922_RS05675	COG3599	regulation of cell shape
CR922_RS05700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CR922_RS05710	COG0849	cell division
CR922_RS05735	COG1217	gtp-binding protein TYPA
CR922_RS05740	COG1940	carbohydrate kinase activity
CR922_RS05745	COG4483	Protein conserved in bacteria
CR922_RS05750	COG0735	belongs to the Fur family
CR922_RS05755	COG0783	Belongs to the Dps family
CR922_RS05760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CR922_RS05770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CR922_RS05800	COG1704	LemA family
CR922_RS05830	COG0732	type I restriction modification DNA specificity domain
CR922_RS05845	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CR922_RS05850	COG4221	oxidoreductase activity
CR922_RS05885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CR922_RS05890	COG0406	alpha-ribazole phosphatase activity
CR922_RS05975	COG0494	nUDIX hydrolase
CR922_RS05985	COG1914	H( )-stimulated, divalent metal cation uptake system
CR922_RS05990	COG4443	Transcriptional Coactivator p15 (PC4)
CR922_RS06000	COG1268	BioY protein
CR922_RS06010	COG0826	peptidase U32
CR922_RS06035	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CR922_RS06055	COG2183	response to ionizing radiation
CR922_RS06060	COG0701	Predicted permease
CR922_RS06065	COG3689	TIGRFAM TIGR03943 family protein
CR922_RS06075	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CR922_RS06080	COG1518	maintenance of DNA repeat elements
CR922_RS06140	COG0077	Prephenate dehydratase
CR922_RS06165	COG0287	Prephenate dehydrogenase
CR922_RS06190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CR922_RS06195	COG1368	sulfuric ester hydrolase activity
CR922_RS06230	COG1609	Transcriptional regulator
CR922_RS06235	COG0006	proline dipeptidase activity
CR922_RS06240	COG1185	polyribonucleotide nucleotidyltransferase activity
CR922_RS06255	COG0557	exoribonuclease II activity
CR922_RS06270	COG2814	Major facilitator Superfamily
CR922_RS06275	COG0237	dephospho-CoA kinase activity
CR922_RS06285	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CR922_RS06290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CR922_RS06300	COG3711	transcriptional antiterminator
CR922_RS06315	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CR922_RS06320	COG0768	penicillin binding
CR922_RS06325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CR922_RS06330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CR922_RS06365	COG0765	amino acid transport
CR922_RS06370	COG4703	Protein of unknown function (DUF1797)
CR922_RS06375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CR922_RS06380	COG0542	response to heat
CR922_RS06385	COG0494	nUDIX hydrolase
CR922_RS06425	COG0539	negative regulation of cytoplasmic translation
CR922_RS06445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CR922_RS06455	COG0187	DNA topoisomerase II activity
CR922_RS06475	COG2040	homocysteine
CR922_RS06480	COG0833	amino acid
CR922_RS06500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CR922_RS06510	COG3425	synthase
CR922_RS06530	COG1272	protein, Hemolysin III
CR922_RS06560	COG0438	transferase activity, transferring glycosyl groups
CR922_RS06625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CR922_RS06635	COG0686	Belongs to the AlaDH PNT family
CR922_RS06640	COG1473	amidohydrolase
CR922_RS06645	COG1187	pseudouridine synthase activity
CR922_RS06680	COG1131	(ABC) transporter
CR922_RS06690	COG3279	Response regulator of the LytR AlgR family
CR922_RS06755	COG0505	Belongs to the CarA family
CR922_RS06775	COG0564	pseudouridine synthase activity
CR922_RS06785	COG0583	DNA-binding transcription factor activity
CR922_RS06820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR922_RS06820	COG1263	PTS System
CR922_RS06820	COG2190	(PTS) system
CR922_RS06825	COG1263	PTS System
CR922_RS06825	COG2190	(PTS) system
CR922_RS06825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CR922_RS06835	COG1113	amino acid transport
CR922_RS06880	COG1705	Flagellar rod assembly protein muramidase FlgJ
CR922_RS06880	COG1388	LysM domain
CR922_RS06885	COG0347	Belongs to the P(II) protein family
CR922_RS06890	COG0004	ammonium transporteR
CR922_RS06900	COG4467	Involved in initiation control of chromosome replication
CR922_RS06905	COG1774	PSP1 C-terminal conserved region
CR922_RS06910	COG0470	DNA polymerase III
CR922_RS06930	COG0772	Belongs to the SEDS family
CR922_RS06965	COG0356	it plays a direct role in the translocation of protons across the membrane
CR922_RS07005	COG2962	Rard protein
CR922_RS07020	COG0726	polysaccharide deacetylase
CR922_RS07025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CR922_RS07030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CR922_RS07045	COG0436	Aminotransferase
CR922_RS07050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CR922_RS07075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CR922_RS07080	COG4122	O-methyltransferase activity
CR922_RS07110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR922_RS07110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR922_RS07130	COG1702	phosphate starvation-inducible protein PhoH
CR922_RS07195	COG0242	peptide deformylase activity
CR922_RS07200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CR922_RS07220	COG0488	(ABC) transporter
CR922_RS07290	COG1104	cysteine desulfurase activity
CR922_RS07300	COG0285	dihydrofolate synthase activity
CR922_RS07305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CR922_RS07315	COG1105	Belongs to the carbohydrate kinase PfkB family
CR922_RS07320	COG1349	DNA-binding transcription factor activity
CR922_RS07365	COG0439	Biotin carboxylase
CR922_RS07380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CR922_RS07385	COG1028	Short-chain dehydrogenase reductase Sdr
CR922_RS07390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CR922_RS07415	COG1024	Enoyl-CoA hydratase
CR922_RS07420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CR922_RS07425	COG0527	aspartate kinase activity
CR922_RS07520	COG1040	competence protein
CR922_RS07525	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CR922_RS07530	COG1739	Uncharacterized protein family UPF0029
CR922_RS07560	COG0559	Belongs to the binding-protein-dependent transport system permease family
CR922_RS07570	COG4471	UPF0298 protein
CR922_RS07605	COG0626	cystathionine gamma-synthase activity
CR922_RS07615	COG2244	polysaccharide biosynthetic process
CR922_RS07635	COG1611	Belongs to the LOG family
CR922_RS07655	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CR922_RS07660	COG0195	Participates in both transcription termination and antitermination
CR922_RS07670	COG1316	TRANSCRIPTIONal
CR922_RS07675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CR922_RS07680	COG0802	atpase or kinase
CR922_RS07685	COG2252	PERMEase
CR922_RS07690	COG0561	phosphatase activity
CR922_RS07695	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CR922_RS07705	COG3715	PTS system
CR922_RS07710	COG3716	PTS system mannose fructose sorbose family IID component
CR922_RS07740	COG1132	(ABC) transporter
CR922_RS07750	COG1484	DNA-dependent DNA replication
CR922_RS07765	COG5002	protein histidine kinase activity
CR922_RS07770	COG0745	RESPONSE REGULATOR receiver
CR922_RS07785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CR922_RS07800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CR922_RS07810	COG1122	ATPase activity
CR922_RS07825	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CR922_RS07855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CR922_RS07860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CR922_RS07865	COG1122	ATPase activity
CR922_RS07875	COG0310	cobalt ion transport
CR922_RS07930	COG2274	protein secretion by the type I secretion system
CR922_RS07935	COG2274	protein secretion by the type I secretion system
CR922_RS07940	COG2274	protein secretion by the type I secretion system
CR922_RS07945	COG2274	protein secretion by the type I secretion system
CR922_RS07955	COG0671	phosphoesterase, PA-phosphatase related
CR922_RS07960	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CR922_RS07970	COG0569	domain protein
CR922_RS07975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CR922_RS07985	COG1187	pseudouridine synthase activity
CR922_RS08060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CR922_RS08065	COG1254	Belongs to the acylphosphatase family
CR922_RS08090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CR922_RS08110	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CR922_RS08125	COG0116	Belongs to the methyltransferase superfamily
CR922_RS08150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR922_RS08155	COG3579	cysteine-type endopeptidase activity
CR922_RS08170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CR922_RS08235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR922_RS08240	COG0564	pseudouridine synthase activity
CR922_RS08275	COG1116	anion transmembrane transporter activity
CR922_RS08275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CR922_RS08280	COG4120	Belongs to the binding-protein-dependent transport system permease family
CR922_RS08295	COG4589	Belongs to the CDS family
CR922_RS08335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CR922_RS08340	COG1121	(ABC) transporter
CR922_RS08365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CR922_RS08380	COG4608	Belongs to the ABC transporter superfamily
CR922_RS08405	COG0719	Fe-S assembly protein
CR922_RS08415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CR922_RS08420	COG0719	Fe-S assembly protein
CR922_RS08430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CR922_RS08435	COG4862	establishment of competence for transformation
CR922_RS08445	COG1968	undecaprenyl-diphosphatase activity
CR922_RS08450	COG0765	amino acid transport
CR922_RS08455	COG1126	abc transporter atp-binding protein
CR922_RS08490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CR922_RS08530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CR922_RS08550	COG0504	CTP synthase activity
CR922_RS08565	COG0668	transmembrane transport
CR922_RS08585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CR922_RS08590	COG1473	amidohydrolase
CR922_RS08610	COG4166	transmembrane transport
CR922_RS08665	COG0706	membrane insertase activity
CR922_RS08690	COG4166	transmembrane transport
CR922_RS08695	COG4166	transmembrane transport
CR922_RS08730	COG0756	dUTP diphosphatase activity
CR922_RS08760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CR922_RS08765	COG0457	Tetratricopeptide repeat
CR922_RS08765	COG0705	Rhomboid family
CR922_RS08770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CR922_RS08790	COG2226	methyltransferase
CR922_RS08820	COG0425	Belongs to the sulfur carrier protein TusA family
CR922_RS08825	COG2391	methyltransferase activity
CR922_RS08830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CR922_RS08835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CR922_RS08845	COG1363	Peptidase, m42
CR922_RS08850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CR922_RS08855	COG1266	CAAX protease self-immunity
CR922_RS08910	COG1459	type II secretion system
CR922_RS08915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CR922_RS08935	COG4499	WXG100 protein secretion system (Wss), protein YukC
CR922_RS08935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CR922_RS08950	COG0440	acetolactate synthase activity
CR922_RS08955	COG0028	Belongs to the TPP enzyme family
CR922_RS08965	COG1461	Dihydroxyacetone kinase
CR922_RS08975	COG0534	Mate efflux family protein
CR922_RS08995	COG1454	alcohol dehydrogenase
CR922_RS08995	COG1012	belongs to the aldehyde dehydrogenase family
CR922_RS09000	COG1012	belongs to the aldehyde dehydrogenase family
CR922_RS09000	COG1454	alcohol dehydrogenase
CR922_RS09010	COG1454	alcohol dehydrogenase
CR922_RS09010	COG1012	belongs to the aldehyde dehydrogenase family
CR922_RS09015	COG3590	peptidase
CR922_RS09030	COG1609	Transcriptional regulator
CR922_RS09035	COG2188	Transcriptional regulator
CR922_RS09065	COG0191	fructose-bisphosphate aldolase activity
CR922_RS09135	COG0201	protein transport
CR922_RS09280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CR922_RS09295	COG0515	serine threonine protein kinase
CR922_RS09305	COG1396	sequence-specific DNA binding
CR922_RS09310	COG0535	radical SAM domain protein
CR922_RS09315	COG1132	(ABC) transporter
CR922_RS09345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CR922_RS09375	COG1328	CTP reductase activity
CR922_RS09390	COG0602	queuosine metabolic process
CR922_RS09400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR922_RS09425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CR922_RS09430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CR922_RS09440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CR922_RS09460	COG1597	lipid kinase activity
CR922_RS09475	COG2261	transglycosylase associated protein
CR922_RS09495	COG3237	CsbD-like
CR922_RS09520	COG1511	domain protein
CR922_RS09520	COG1511	domain protein
CR922_RS09530	COG3759	membrane
CR922_RS09545	COG0305	Participates in initiation and elongation during chromosome replication
CR922_RS09575	COG0741	lytic transglycosylase activity
CR922_RS09580	COG3584	3D domain protein
CR922_RS09580	COG1388	LysM domain
CR922_RS09585	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CR922_RS09600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CR922_RS09610	COG0612	Peptidase, M16
CR922_RS09640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CR922_RS09645	COG0488	(ABC) transporter
CR922_RS09680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CR922_RS09685	COG1475	DNA binding