locus-tag	class	description
GQY29_RS00030	COG0686	Belongs to the AlaDH PNT family
GQY29_RS00050	COG0686	Belongs to the AlaDH PNT family
GQY29_RS00055	COG0686	Belongs to the AlaDH PNT family
GQY29_RS00060	COG1473	amidohydrolase
GQY29_RS00065	COG1187	pseudouridine synthase activity
GQY29_RS00100	COG1131	(ABC) transporter
GQY29_RS00110	COG3279	Response regulator of the LytR AlgR family
GQY29_RS00200	COG0577	efflux transmembrane transporter activity
GQY29_RS00205	COG0577	efflux transmembrane transporter activity
GQY29_RS00240	COG0505	Belongs to the CarA family
GQY29_RS00260	COG0564	pseudouridine synthase activity
GQY29_RS00270	COG0583	DNA-binding transcription factor activity
GQY29_RS00305	COG2190	(PTS) system
GQY29_RS00305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQY29_RS00305	COG1263	PTS System
GQY29_RS00310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQY29_RS00310	COG1263	PTS System
GQY29_RS00310	COG2190	(PTS) system
GQY29_RS00320	COG1113	amino acid transport
GQY29_RS00365	COG1705	Flagellar rod assembly protein muramidase FlgJ
GQY29_RS00365	COG1388	LysM domain
GQY29_RS00370	COG0347	Belongs to the P(II) protein family
GQY29_RS00375	COG0004	ammonium transporteR
GQY29_RS00385	COG4467	Involved in initiation control of chromosome replication
GQY29_RS00390	COG1774	PSP1 C-terminal conserved region
GQY29_RS00395	COG0470	DNA polymerase III
GQY29_RS00415	COG0772	Belongs to the SEDS family
GQY29_RS00440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GQY29_RS00450	COG0356	it plays a direct role in the translocation of protons across the membrane
GQY29_RS00475	COG1204	response to ionizing radiation
GQY29_RS00510	COG2962	Rard protein
GQY29_RS00525	COG0726	polysaccharide deacetylase
GQY29_RS00530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GQY29_RS00535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GQY29_RS00550	COG0436	Aminotransferase
GQY29_RS00555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GQY29_RS00585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GQY29_RS00615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQY29_RS00615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQY29_RS00635	COG1702	phosphate starvation-inducible protein PhoH
GQY29_RS00645	COG3942	CHAP domain
GQY29_RS00695	COG0242	peptide deformylase activity
GQY29_RS00700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQY29_RS00705	COG3328	transposase activity
GQY29_RS00725	COG0488	(ABC) transporter
GQY29_RS00785	COG1104	cysteine desulfurase activity
GQY29_RS00795	COG0285	dihydrofolate synthase activity
GQY29_RS00800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQY29_RS00805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQY29_RS00805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GQY29_RS00805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GQY29_RS00810	COG1105	Belongs to the carbohydrate kinase PfkB family
GQY29_RS00815	COG1349	DNA-binding transcription factor activity
GQY29_RS00835	COG3316	Transposase and inactivated derivatives
GQY29_RS00850	COG0531	amino acid
GQY29_RS00855	COG0076	glutamate decarboxylase activity
GQY29_RS00870	COG0732	type I restriction modification DNA specificity domain
GQY29_RS00890	COG0439	Biotin carboxylase
GQY29_RS00905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GQY29_RS00910	COG1028	Short-chain dehydrogenase reductase Sdr
GQY29_RS00915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GQY29_RS00935	COG1846	Transcriptional regulator
GQY29_RS00940	COG1024	Enoyl-CoA hydratase
GQY29_RS00945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQY29_RS00950	COG0527	aspartate kinase activity
GQY29_RS01040	COG1040	competence protein
GQY29_RS01045	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GQY29_RS01050	COG1739	Uncharacterized protein family UPF0029
GQY29_RS01070	COG0411	ABC transporter
GQY29_RS01080	COG0559	Belongs to the binding-protein-dependent transport system permease family
GQY29_RS01090	COG4471	UPF0298 protein
GQY29_RS01120	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GQY29_RS01125	COG0626	cystathionine gamma-synthase activity
GQY29_RS01130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQY29_RS01135	COG2244	polysaccharide biosynthetic process
GQY29_RS01170	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GQY29_RS01175	COG0195	Participates in both transcription termination and antitermination
GQY29_RS01185	COG1316	TRANSCRIPTIONal
GQY29_RS01190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQY29_RS01195	COG0802	atpase or kinase
GQY29_RS01200	COG2252	PERMEase
GQY29_RS01205	COG0561	phosphatase activity
GQY29_RS01210	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GQY29_RS01220	COG3715	PTS system
GQY29_RS01225	COG3716	PTS system mannose fructose sorbose family IID component
GQY29_RS01260	COG1484	DNA-dependent DNA replication
GQY29_RS01275	COG5002	protein histidine kinase activity
GQY29_RS01280	COG0745	RESPONSE REGULATOR receiver
GQY29_RS01295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQY29_RS01305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GQY29_RS01315	COG1122	ATPase activity
GQY29_RS01340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GQY29_RS01350	COG1464	Belongs to the NlpA lipoprotein family
GQY29_RS01355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQY29_RS01375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GQY29_RS01380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQY29_RS01385	COG1122	ATPase activity
GQY29_RS01395	COG0310	cobalt ion transport
GQY29_RS01400	COG0829	nickel cation binding
GQY29_RS01405	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GQY29_RS01415	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GQY29_RS01425	COG0832	Belongs to the urease beta subunit family
GQY29_RS01430	COG0831	urea catabolic process
GQY29_RS01450	COG2274	protein secretion by the type I secretion system
GQY29_RS01455	COG2274	protein secretion by the type I secretion system
GQY29_RS01460	COG2274	protein secretion by the type I secretion system
GQY29_RS01475	COG0671	phosphoesterase, PA-phosphatase related
GQY29_RS01480	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GQY29_RS01490	COG0569	domain protein
GQY29_RS01495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQY29_RS01505	COG1187	pseudouridine synthase activity
GQY29_RS01510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GQY29_RS01515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GQY29_RS01535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQY29_RS01545	COG3763	UPF0154 protein
GQY29_RS01580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQY29_RS01585	COG1254	Belongs to the acylphosphatase family
GQY29_RS01610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GQY29_RS01630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GQY29_RS01640	COG0116	Belongs to the methyltransferase superfamily
GQY29_RS01665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQY29_RS01670	COG3579	cysteine-type endopeptidase activity
GQY29_RS01685	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GQY29_RS01715	COG1349	DNA-binding transcription factor activity
GQY29_RS01745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GQY29_RS01750	COG0564	pseudouridine synthase activity
GQY29_RS01795	COG1116	anion transmembrane transporter activity
GQY29_RS01795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GQY29_RS01800	COG4120	Belongs to the binding-protein-dependent transport system permease family
GQY29_RS01815	COG4589	Belongs to the CDS family
GQY29_RS01830	COG0217	transcriptional regulatory protein
GQY29_RS01855	COG1263	PTS System
GQY29_RS01855	COG2190	(PTS) system
GQY29_RS01855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQY29_RS01870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GQY29_RS01875	COG1121	(ABC) transporter
GQY29_RS01890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GQY29_RS01930	COG0719	Fe-S assembly protein
GQY29_RS01940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQY29_RS01945	COG0719	Fe-S assembly protein
GQY29_RS01955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQY29_RS01970	COG1968	undecaprenyl-diphosphatase activity
GQY29_RS01975	COG0765	amino acid transport
GQY29_RS01980	COG1126	abc transporter atp-binding protein
GQY29_RS02015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GQY29_RS02055	COG0737	Belongs to the 5'-nucleotidase family
GQY29_RS02070	COG0737	Belongs to the 5'-nucleotidase family
GQY29_RS02075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GQY29_RS02085	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQY29_RS02095	COG0504	CTP synthase activity
GQY29_RS02110	COG0668	transmembrane transport
GQY29_RS02135	COG1473	amidohydrolase
GQY29_RS02245	COG0351	phosphomethylpyrimidine kinase
GQY29_RS02280	COG1876	peptidase activity
GQY29_RS02295	COG3830	Belongs to the UPF0237 family
GQY29_RS02310	COG3942	CHAP domain
GQY29_RS02310	COG1705	Flagellar rod assembly protein muramidase FlgJ
GQY29_RS02330	COG3421	Type III restriction
GQY29_RS02335	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GQY29_RS02385	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQY29_RS02410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GQY29_RS02425	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GQY29_RS02435	COG1045	serine acetyltransferase
GQY29_RS02450	COG1686	Belongs to the peptidase S11 family
GQY29_RS02460	COG0542	response to heat
GQY29_RS02465	COG4463	regulation of RNA biosynthetic process
GQY29_RS02505	COG0431	NADPH-dependent FMN reductase
GQY29_RS02520	COG2309	aminopeptidase activity
GQY29_RS02610	COG1393	Belongs to the ArsC family
GQY29_RS02625	COG2818	Glycosylase
GQY29_RS02665	COG4550	Control of competence regulator ComK, YlbF/YmcA
GQY29_RS02680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GQY29_RS02705	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GQY29_RS02710	COG0151	Belongs to the GarS family
GQY29_RS02715	COG3942	CHAP domain
GQY29_RS02715	COG1388	LysM domain
GQY29_RS02730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GQY29_RS02745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQY29_RS02770	COG0436	Aminotransferase
GQY29_RS02780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQY29_RS02785	COG3942	CHAP domain
GQY29_RS02915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQY29_RS02945	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GQY29_RS02950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GQY29_RS02960	COG0012	GTP binding
GQY29_RS02970	COG0592	DNA-directed DNA polymerase activity
GQY29_RS02980	COG1475	DNA binding
GQY29_RS02985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQY29_RS03020	COG0488	(ABC) transporter
GQY29_RS03025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GQY29_RS03065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQY29_RS03080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GQY29_RS03085	COG3584	3D domain protein
GQY29_RS03085	COG1388	LysM domain
GQY29_RS03090	COG0741	lytic transglycosylase activity
GQY29_RS03120	COG0305	Participates in initiation and elongation during chromosome replication
GQY29_RS03220	COG3759	membrane
GQY29_RS03230	COG1511	domain protein
GQY29_RS03230	COG1511	domain protein
GQY29_RS03255	COG3237	CsbD-like
GQY29_RS03275	COG2261	transglycosylase associated protein
GQY29_RS03315	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GQY29_RS03340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GQY29_RS03350	COG0602	queuosine metabolic process
GQY29_RS03365	COG1328	CTP reductase activity
GQY29_RS03395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GQY29_RS03420	COG1132	(ABC) transporter
GQY29_RS03430	COG1396	sequence-specific DNA binding
GQY29_RS03435	COG1396	sequence-specific DNA binding
GQY29_RS03440	COG1132	(ABC) transporter
GQY29_RS03445	COG0515	serine threonine protein kinase
GQY29_RS03460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GQY29_RS03605	COG0201	protein transport
GQY29_RS03620	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GQY29_RS03670	COG0191	fructose-bisphosphate aldolase activity
GQY29_RS03675	COG0582	viral genome integration into host DNA
GQY29_RS03685	COG1705	Flagellar rod assembly protein muramidase FlgJ
GQY29_RS03685	COG3942	CHAP domain
GQY29_RS03700	COG0433	COG0433 Predicted ATPase
GQY29_RS03735	COG1674	ftsk spoiiie
GQY29_RS03750	COG3620	sequence-specific DNA binding
GQY29_RS03775	COG3620	sequence-specific DNA binding
GQY29_RS03870	COG1301	dicarboxylic acid transport
GQY29_RS03885	COG0582	viral genome integration into host DNA
GQY29_RS03890	COG3328	transposase activity
GQY29_RS03915	COG2217	Heavy metal translocating P-type atpase
GQY29_RS03935	COG4166	transmembrane transport
GQY29_RS03965	COG4475	Protein of unknown function (DUF436)
GQY29_RS03970	COG2188	Transcriptional regulator
GQY29_RS03975	COG1609	Transcriptional regulator
GQY29_RS03990	COG3590	peptidase
GQY29_RS03995	COG1012	belongs to the aldehyde dehydrogenase family
GQY29_RS03995	COG1454	alcohol dehydrogenase
GQY29_RS04005	COG1454	alcohol dehydrogenase
GQY29_RS04005	COG1012	belongs to the aldehyde dehydrogenase family
GQY29_RS04010	COG1012	belongs to the aldehyde dehydrogenase family
GQY29_RS04010	COG1454	alcohol dehydrogenase
GQY29_RS04015	COG1454	alcohol dehydrogenase
GQY29_RS04015	COG1012	belongs to the aldehyde dehydrogenase family
GQY29_RS04030	COG0534	Mate efflux family protein
GQY29_RS04040	COG1461	Dihydroxyacetone kinase
GQY29_RS04050	COG0028	Belongs to the TPP enzyme family
GQY29_RS04055	COG0440	acetolactate synthase activity
GQY29_RS04090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GQY29_RS04095	COG1459	type II secretion system
GQY29_RS04155	COG1266	CAAX protease self-immunity
GQY29_RS04160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GQY29_RS04165	COG1363	Peptidase, m42
GQY29_RS04175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GQY29_RS04180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQY29_RS04185	COG2391	methyltransferase activity
GQY29_RS04190	COG0425	Belongs to the sulfur carrier protein TusA family
GQY29_RS04220	COG2226	methyltransferase
GQY29_RS04240	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GQY29_RS04245	COG0457	Tetratricopeptide repeat
GQY29_RS04245	COG0705	Rhomboid family
GQY29_RS04250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GQY29_RS04280	COG0756	dUTP diphosphatase activity
GQY29_RS04345	COG0706	membrane insertase activity
GQY29_RS04365	COG1943	Transposase
GQY29_RS04410	COG3118	belongs to the thioredoxin family
GQY29_RS04415	COG1832	CoA-binding protein
GQY29_RS04420	COG0084	hydrolase, TatD family'
GQY29_RS04455	COG1322	Protein conserved in bacteria
GQY29_RS04465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GQY29_RS04520	COG0789	Transcriptional regulator
GQY29_RS04525	COG0174	glutamine synthetase
GQY29_RS04545	COG1214	PFAM Peptidase M22, glycoprotease
GQY29_RS04550	COG0456	acetyltransferase
GQY29_RS04560	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GQY29_RS04570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GQY29_RS04575	COG0681	Belongs to the peptidase S26 family
GQY29_RS04600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQY29_RS04600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GQY29_RS04690	COG0006	proline dipeptidase activity
GQY29_RS04695	COG2131	deaminase
GQY29_RS04715	COG1609	Transcriptional regulator
GQY29_RS04720	COG1621	beta-fructofuranosidase activity
GQY29_RS04725	COG1263	PTS System
GQY29_RS04725	COG2190	(PTS) system
GQY29_RS04725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GQY29_RS04730	COG1940	carbohydrate kinase activity
GQY29_RS04735	COG1482	cell wall glycoprotein biosynthetic process
GQY29_RS04750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQY29_RS04755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GQY29_RS04765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GQY29_RS04770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GQY29_RS04775	COG0252	asparaginase activity
GQY29_RS04780	COG0561	phosphatase activity
GQY29_RS04810	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GQY29_RS04820	COG1811	Na channel or pump
GQY29_RS04825	COG4152	abc transporter atp-binding protein
GQY29_RS04850	COG3152	Membrane
GQY29_RS04880	COG0768	penicillin binding
GQY29_RS04890	COG0513	Belongs to the DEAD box helicase family
GQY29_RS04895	COG0737	Belongs to the 5'-nucleotidase family
GQY29_RS04900	COG4470	Protein conserved in bacteria
GQY29_RS04920	COG1132	(ABC) transporter
GQY29_RS04925	COG1132	(ABC) transporter
GQY29_RS04930	COG2274	protein secretion by the type I secretion system
GQY29_RS04935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GQY29_RS04945	COG3290	protein histidine kinase activity
GQY29_RS05025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GQY29_RS05040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GQY29_RS05045	COG4619	ABC transporter
GQY29_RS05050	COG0390	transport system, permease component
GQY29_RS05075	COG1882	Formate acetyltransferase
GQY29_RS05090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQY29_RS05100	COG1126	abc transporter atp-binding protein
GQY29_RS05110	COG0492	ferredoxin-NADP+ reductase activity
GQY29_RS05115	COG0742	ribosomal rna small subunit methyltransferase
GQY29_RS05120	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GQY29_RS05125	COG3480	Lon protease (S16) C-terminal proteolytic domain
GQY29_RS05130	COG1242	4 iron, 4 sulfur cluster binding
GQY29_RS05135	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GQY29_RS05145	COG0025	NhaP-type Na H and K H
GQY29_RS05150	COG1119	ATPase activity
GQY29_RS05155	COG1253	flavin adenine dinucleotide binding
GQY29_RS05165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GQY29_RS05180	COG0589	response to stress
GQY29_RS05185	COG0436	Aminotransferase
GQY29_RS05195	COG1335	isochorismatase
GQY29_RS05250	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GQY29_RS05255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GQY29_RS05260	COG1534	Rna-binding protein
GQY29_RS05265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GQY29_RS05270	COG1713	HD superfamily hydrolase involved in NAD metabolism
GQY29_RS05275	COG0799	negative regulation of ribosome biogenesis
GQY29_RS05280	COG2226	methyltransferase
GQY29_RS05310	COG0537	adenosine 5'-monophosphoramidase activity
GQY29_RS05315	COG1131	(ABC) transporter
GQY29_RS05340	COG2081	HI0933 family
GQY29_RS05350	COG2151	metal-sulfur cluster biosynthetic enzyme
GQY29_RS05360	COG2176	DNA-directed DNA polymerase activity
GQY29_RS05385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQY29_RS05395	COG0287	Prephenate dehydrogenase
GQY29_RS05395	COG1605	Chorismate mutase
GQY29_RS05400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQY29_RS05405	COG0512	Glutamine amidotransferase of anthranilate synthase
GQY29_RS05420	COG0135	phosphoribosylanthranilate isomerase activity
GQY29_RS05430	COG0159	tryptophan synthase activity
GQY29_RS05440	COG2217	Heavy metal translocating P-type atpase
GQY29_RS05455	COG0765	amino acid transport
GQY29_RS05460	COG0765	amino acid transport
GQY29_RS05465	COG1126	abc transporter atp-binding protein
GQY29_RS05470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQY29_RS05485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GQY29_RS05500	COG2211	Major facilitator Superfamily
GQY29_RS05505	COG1396	sequence-specific DNA binding
GQY29_RS05525	COG0513	Belongs to the DEAD box helicase family
GQY29_RS05535	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GQY29_RS05540	COG0726	polysaccharide deacetylase
GQY29_RS05550	COG0204	Acyl-transferase
GQY29_RS05570	COG1129	ABC transporter
GQY29_RS05570	COG0842	Transport permease protein
GQY29_RS05595	COG1596	polysaccharide export
GQY29_RS05595	COG1555	photosystem II stabilization
GQY29_RS05600	COG0658	competence protein
GQY29_RS05600	COG2333	competence protein COMEC
GQY29_RS05605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GQY29_RS05615	COG4109	DRTGG domain
GQY29_RS05620	COG0024	Methionine aminopeptidase
GQY29_RS05630	COG4708	membrane
GQY29_RS05640	COG1597	lipid kinase activity
GQY29_RS05655	COG0708	Exodeoxyribonuclease III
GQY29_RS05660	COG0500	methyltransferase
GQY29_RS05660	COG3615	Tellurite resistance protein tehB
GQY29_RS05670	COG1837	Belongs to the UPF0109 family
GQY29_RS05675	COG0285	dihydrofolate synthase activity
GQY29_RS05680	COG0531	amino acid
GQY29_RS05720	COG1176	ABC-type spermidine putrescine transport system, permease component I
GQY29_RS05725	COG1177	transmembrane transport
GQY29_RS05730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GQY29_RS05760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQY29_RS05770	COG1393	Belongs to the ArsC family
GQY29_RS05780	COG1380	Effector of murein hydrolase LrgA
GQY29_RS05785	COG1346	cytolysis
GQY29_RS05795	COG0187	DNA topoisomerase II activity
GQY29_RS05805	COG0560	Phosphoserine phosphatase
GQY29_RS05815	COG1518	maintenance of DNA repeat elements
GQY29_RS05820	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GQY29_RS05865	COG1187	pseudouridine synthase activity
GQY29_RS05885	COG1126	abc transporter atp-binding protein
GQY29_RS05890	COG0765	amino acid transport
GQY29_RS05910	COG1051	belongs to the nudix hydrolase family
GQY29_RS05915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQY29_RS05920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQY29_RS05945	COG0358	DNA primase activity
GQY29_RS05950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GQY29_RS05955	COG2151	metal-sulfur cluster biosynthetic enzyme
GQY29_RS05960	COG0463	Glycosyl transferase, family 2
GQY29_RS05970	COG1091	dTDP-4-dehydrorhamnose reductase activity
GQY29_RS05975	COG0463	Glycosyl transferase, family 2
GQY29_RS05990	COG1216	Glycosyl transferase, family 2
GQY29_RS05990	COG1442	glycosyl transferase family 8
GQY29_RS06005	COG1215	transferase activity, transferring glycosyl groups
GQY29_RS06035	COG2003	Belongs to the UPF0758 family
GQY29_RS06040	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GQY29_RS06055	COG1104	cysteine desulfurase activity
GQY29_RS06060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQY29_RS06070	COG2357	RelA SpoT domain protein
GQY29_RS06080	COG0564	pseudouridine synthase activity
GQY29_RS06085	COG0280	phosphate acetyltransferase
GQY29_RS06100	COG0084	hydrolase, TatD family'
GQY29_RS06105	COG4608	Belongs to the ABC transporter superfamily
GQY29_RS06110	COG4608	Belongs to the ABC transporter superfamily
GQY29_RS06120	COG4166	transmembrane transport
GQY29_RS06130	COG4166	transmembrane transport
GQY29_RS06135	COG0601	transmembrane transport
GQY29_RS06140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQY29_RS06145	COG0444	Belongs to the ABC transporter superfamily
GQY29_RS06150	COG4608	Belongs to the ABC transporter superfamily
GQY29_RS06160	COG1131	(ABC) transporter
GQY29_RS06165	COG1725	Transcriptional regulator
GQY29_RS06170	COG0561	phosphatase activity
GQY29_RS06175	COG0561	phosphatase activity
GQY29_RS06180	COG0552	protein localization to endoplasmic reticulum
GQY29_RS06195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GQY29_RS06205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQY29_RS06205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQY29_RS06215	COG2815	serine threonine protein kinase
GQY29_RS06215	COG0515	serine threonine protein kinase
GQY29_RS06230	COG4585	Histidine kinase
GQY29_RS06235	COG2197	response regulator
GQY29_RS06255	COG0336	Belongs to the RNA methyltransferase TrmD family
GQY29_RS06290	COG0488	(ABC) transporter
GQY29_RS06315	COG1609	Transcriptional regulator
GQY29_RS06330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GQY29_RS06335	COG2017	converts alpha-aldose to the beta-anomer
GQY29_RS06340	COG2190	(PTS) system
GQY29_RS06340	COG2211	Major facilitator Superfamily
GQY29_RS06345	COG3250	beta-galactosidase activity
GQY29_RS06355	COG0420	3'-5' exonuclease activity
GQY29_RS06360	COG0419	ATPase involved in DNA repair
GQY29_RS06375	COG1396	sequence-specific DNA binding
GQY29_RS06440	COG0577	efflux transmembrane transporter activity
GQY29_RS06445	COG1216	Glycosyl transferase, family 2
GQY29_RS06445	COG1442	glycosyl transferase family 8
GQY29_RS06460	COG1280	lysine exporter protein (LysE YggA)
GQY29_RS06485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GQY29_RS06530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GQY29_RS06535	COG0656	L-ascorbic acid biosynthetic process
GQY29_RS06545	COG0778	Nitroreductase
GQY29_RS06550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GQY29_RS06550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GQY29_RS06560	COG1959	2 iron, 2 sulfur cluster binding
GQY29_RS06565	COG2514	catechol 2,3-dioxygenase activity
GQY29_RS06575	COG0531	amino acid
GQY29_RS06610	COG0371	Dehydrogenase
GQY29_RS06620	COG0436	Aminotransferase
GQY29_RS06625	COG2079	MmgE PrpD family protein
GQY29_RS06635	COG0765	amino acid transport
GQY29_RS06640	COG1126	abc transporter atp-binding protein
GQY29_RS06655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQY29_RS06655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GQY29_RS06660	COG0534	Mate efflux family protein
GQY29_RS06675	COG0745	RESPONSE REGULATOR receiver
GQY29_RS06680	COG2198	Histidine kinase
GQY29_RS06680	COG0784	Response regulator, receiver
GQY29_RS06680	COG5002	protein histidine kinase activity
GQY29_RS06685	COG1136	(ABC) transporter
GQY29_RS06690	COG0577	efflux transmembrane transporter activity
GQY29_RS06725	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GQY29_RS06760	COG1131	(ABC) transporter
GQY29_RS06770	COG4585	Histidine kinase
GQY29_RS06775	COG2197	response regulator
GQY29_RS06800	COG1760	l-serine dehydratase
GQY29_RS06805	COG1760	l-serine dehydratase
GQY29_RS06810	COG1011	Hydrolase
GQY29_RS06820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GQY29_RS06830	COG1247	-acetyltransferase
GQY29_RS06840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GQY29_RS06855	COG1196	nuclear chromosome segregation
GQY29_RS06885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GQY29_RS06885	COG1328	CTP reductase activity
GQY29_RS06890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQY29_RS06915	COG0488	(ABC) transporter
GQY29_RS06935	COG3764	Sortase (surface protein transpeptidase)
GQY29_RS06940	COG0346	lactoylglutathione lyase activity
GQY29_RS06965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQY29_RS06970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQY29_RS06975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GQY29_RS06980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GQY29_RS06985	COG0372	Belongs to the citrate synthase family
GQY29_RS07015	COG0513	Belongs to the DEAD box helicase family
GQY29_RS07025	COG0488	(ABC) transporter
GQY29_RS07030	COG2267	carboxylic ester hydrolase activity
GQY29_RS07035	COG0392	lysyltransferase activity
GQY29_RS07035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GQY29_RS07040	COG3442	glutamine amidotransferase
GQY29_RS07045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GQY29_RS07060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQY29_RS07070	COG2384	SAM-dependent methyltransferase
GQY29_RS07085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQY29_RS07090	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GQY29_RS07100	COG1088	dTDP-glucose 4,6-dehydratase activity
GQY29_RS07130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GQY29_RS07140	COG0647	UMP catabolic process
GQY29_RS07185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GQY29_RS07195	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GQY29_RS07205	COG0107	imidazoleglycerol-phosphate synthase activity
GQY29_RS07220	COG0772	Belongs to the SEDS family
GQY29_RS07225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQY29_RS07240	COG0300	oxidoreductase activity
GQY29_RS07245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GQY29_RS07245	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GQY29_RS07265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GQY29_RS07275	COG1570	exodeoxyribonuclease VII activity
GQY29_RS07290	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GQY29_RS07295	COG1438	arginine binding
GQY29_RS07300	COG0497	DNA recombination
GQY29_RS07305	COG1307	EDD domain protein, DegV family
GQY29_RS07310	COG2755	lipolytic protein G-D-S-L family
GQY29_RS07320	COG0776	regulation of translation
GQY29_RS07330	COG0167	dihydroorotate dehydrogenase activity
GQY29_RS07380	COG0469	pyruvate kinase activity
GQY29_RS07450	COG0716	FMN binding
GQY29_RS07455	COG0038	chloride channel
GQY29_RS07465	COG0038	chloride channel
GQY29_RS07485	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GQY29_RS07490	COG1956	GAF domain-containing protein
GQY29_RS07495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GQY29_RS07505	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GQY29_RS07505	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GQY29_RS07510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GQY29_RS07555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GQY29_RS07580	COG0765	amino acid transport
GQY29_RS07585	COG0765	amino acid transport
GQY29_RS07590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQY29_RS07595	COG1126	abc transporter atp-binding protein
GQY29_RS07600	COG0745	RESPONSE REGULATOR receiver
GQY29_RS07605	COG5002	protein histidine kinase activity
GQY29_RS07610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GQY29_RS07620	COG2348	transferase activity, transferring amino-acyl groups
GQY29_RS07655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GQY29_RS07665	COG2884	Cell division ATP-binding protein ftsE
GQY29_RS07670	COG2177	Part of the ABC transporter FtsEX involved in
GQY29_RS07675	COG1051	belongs to the nudix hydrolase family
GQY29_RS07680	COG0628	permease
GQY29_RS07690	COG0681	Belongs to the peptidase S26 family
GQY29_RS07725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GQY29_RS07735	COG1943	Transposase
GQY29_RS07755	COG1573	uracil-dna glycosylase
GQY29_RS07770	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GQY29_RS07785	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GQY29_RS07810	COG1316	TRANSCRIPTIONal
GQY29_RS07840	COG0297	glycogen (starch) synthase activity
GQY29_RS07850	COG1442	glycosyl transferase family 8
GQY29_RS07850	COG1216	Glycosyl transferase, family 2
GQY29_RS07855	COG1216	Glycosyl transferase, family 2
GQY29_RS07870	COG0562	UDP-galactopyranose mutase
GQY29_RS07875	COG0438	transferase activity, transferring glycosyl groups
GQY29_RS07930	COG0406	alpha-ribazole phosphatase activity
GQY29_RS07935	COG0628	permease
GQY29_RS07980	COG4667	esterase of the alpha-beta hydrolase superfamily
GQY29_RS07990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GQY29_RS08020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQY29_RS08025	COG0022	dehydrogenase e1 component
GQY29_RS08025	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQY29_RS08030	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQY29_RS08065	COG2822	iron ion transport
GQY29_RS08070	COG2837	iron assimilation
GQY29_RS08075	COG0672	)-iron permease
GQY29_RS08080	COG0805	protein transport
GQY29_RS08085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GQY29_RS08105	COG1640	4-alpha-glucanotransferase
GQY29_RS08120	COG3328	transposase activity
GQY29_RS08130	COG0095	Lipoate-protein ligase
GQY29_RS08145	COG0704	Plays a role in the regulation of phosphate uptake
GQY29_RS08160	COG0581	inorganic phosphate transmembrane transporter activity
GQY29_RS08165	COG0573	inorganic phosphate transmembrane transporter activity
GQY29_RS08170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GQY29_RS08175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQY29_RS08175	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GQY29_RS08180	COG0483	inositol monophosphate 1-phosphatase activity
GQY29_RS08195	COG0196	riboflavin kinase activity
GQY29_RS08200	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQY29_RS08240	COG1115	amino acid carrier protein
GQY29_RS08270	COG3104	oligopeptide transport
GQY29_RS08300	COG1567	CRISPR-associated RAMP protein, Csm4 family
GQY29_RS08305	COG1337	RAMP superfamily
GQY29_RS08325	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GQY29_RS08330	COG1518	maintenance of DNA repeat elements
GQY29_RS08330	COG1468	defense response to virus
GQY29_RS08335	COG0167	dihydroorotate dehydrogenase activity
GQY29_RS08350	COG0047	phosphoribosylformylglycinamidine synthase activity
GQY29_RS08410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GQY29_RS08435	COG1063	alcohol dehydrogenase
GQY29_RS08445	COG1230	cation diffusion facilitator family transporter
GQY29_RS08475	COG3527	Alpha-acetolactate decarboxylase
GQY29_RS08480	COG0028	Belongs to the TPP enzyme family
GQY29_RS08490	COG0010	Belongs to the arginase family
GQY29_RS08495	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQY29_RS08505	COG1396	sequence-specific DNA binding
GQY29_RS08555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQY29_RS08560	COG0758	DNA mediated transformation
GQY29_RS08565	COG1940	carbohydrate kinase activity
GQY29_RS08575	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GQY29_RS08585	COG1827	regulation of RNA biosynthetic process
GQY29_RS08595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQY29_RS08610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQY29_RS08610	COG0519	Catalyzes the synthesis of GMP from XMP
GQY29_RS08620	COG1064	alcohol dehydrogenase
GQY29_RS08625	COG1064	alcohol dehydrogenase
GQY29_RS08645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GQY29_RS08650	COG1126	abc transporter atp-binding protein
GQY29_RS08655	COG0765	amino acid transport
GQY29_RS08660	COG2824	Alkylphosphonate utilization operon protein PhnA
GQY29_RS08665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQY29_RS08680	COG1705	Flagellar rod assembly protein muramidase FlgJ
GQY29_RS08680	COG3942	CHAP domain
GQY29_RS08700	COG0803	Belongs to the bacterial solute-binding protein 9 family
GQY29_RS08700	COG3443	Belongs to the bacterial solute-binding protein 9 family
GQY29_RS08730	COG4975	Glucose uptake
GQY29_RS08740	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GQY29_RS08765	COG0626	cystathionine gamma-synthase activity
GQY29_RS08770	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GQY29_RS08785	COG0582	viral genome integration into host DNA
GQY29_RS08815	COG3328	transposase activity
GQY29_RS08825	COG3328	transposase activity
GQY29_RS08835	COG1278	Cold shock
GQY29_RS08865	COG1660	Displays ATPase and GTPase activities
GQY29_RS08890	COG0720	synthase
GQY29_RS08900	COG0251	oxidation-reduction process
GQY29_RS08920	COG0436	Aminotransferase
GQY29_RS08930	COG1199	ATP-dependent helicase activity
GQY29_RS08930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GQY29_RS08955	COG1744	ABC transporter substrate-binding protein PnrA-like
GQY29_RS08960	COG0295	cytidine deaminase activity
GQY29_RS08980	COG2813	Specifically methylates the guanine in position
GQY29_RS09015	COG0038	chloride channel
GQY29_RS09020	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GQY29_RS09045	COG5002	protein histidine kinase activity
GQY29_RS09070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GQY29_RS09075	COG4684	Psort location CytoplasmicMembrane, score
GQY29_RS09080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQY29_RS09100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GQY29_RS09105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GQY29_RS09120	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GQY29_RS09130	COG1696	Membrane protein involved in D-alanine export
GQY29_RS09145	COG1132	(ABC) transporter
GQY29_RS09150	COG1132	(ABC) transporter
GQY29_RS09175	COG2890	protein-(glutamine-N5) methyltransferase activity
GQY29_RS09185	COG1435	thymidine kinase activity
GQY29_RS09190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GQY29_RS09195	COG0625	glutathione transferase activity
GQY29_RS09200	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GQY29_RS09230	COG3599	regulation of cell shape
GQY29_RS09255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GQY29_RS09295	COG1940	carbohydrate kinase activity
GQY29_RS09300	COG4483	Protein conserved in bacteria
GQY29_RS09305	COG0735	belongs to the Fur family
GQY29_RS09310	COG0783	Belongs to the Dps family
GQY29_RS09315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GQY29_RS09330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GQY29_RS09355	COG0501	Belongs to the peptidase M48B family
GQY29_RS09360	COG1704	LemA family
GQY29_RS09380	COG3620	sequence-specific DNA binding
GQY29_RS09405	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GQY29_RS09410	COG4221	oxidoreductase activity
GQY29_RS09450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GQY29_RS09455	COG0406	alpha-ribazole phosphatase activity
GQY29_RS09470	COG1388	LysM domain
GQY29_RS09470	COG1705	Flagellar rod assembly protein muramidase FlgJ
GQY29_RS09485	COG0494	nUDIX hydrolase
GQY29_RS09495	COG1914	H( )-stimulated, divalent metal cation uptake system
GQY29_RS09500	COG4443	Transcriptional Coactivator p15 (PC4)
GQY29_RS09510	COG1268	BioY protein
GQY29_RS09565	COG2183	response to ionizing radiation
GQY29_RS09570	COG0701	Predicted permease
GQY29_RS09575	COG3689	TIGRFAM TIGR03943 family protein
GQY29_RS09585	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GQY29_RS09590	COG1518	maintenance of DNA repeat elements
GQY29_RS09645	COG1316	TRANSCRIPTIONal
GQY29_RS09650	COG0077	Prephenate dehydratase
GQY29_RS09675	COG0287	Prephenate dehydrogenase
GQY29_RS09700	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQY29_RS09705	COG1368	sulfuric ester hydrolase activity
GQY29_RS09740	COG1609	Transcriptional regulator
GQY29_RS09745	COG0006	proline dipeptidase activity
GQY29_RS09750	COG1185	polyribonucleotide nucleotidyltransferase activity
GQY29_RS09765	COG0557	exoribonuclease II activity
GQY29_RS09780	COG2814	Major facilitator Superfamily
GQY29_RS09785	COG0237	dephospho-CoA kinase activity
GQY29_RS09790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GQY29_RS09795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GQY29_RS09800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GQY29_RS09810	COG3711	transcriptional antiterminator
GQY29_RS09830	COG0768	penicillin binding
GQY29_RS09835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GQY29_RS09870	COG1126	abc transporter atp-binding protein
GQY29_RS09880	COG4703	Protein of unknown function (DUF1797)
GQY29_RS09885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GQY29_RS09890	COG0542	response to heat
GQY29_RS09895	COG0494	nUDIX hydrolase
GQY29_RS09935	COG0539	negative regulation of cytoplasmic translation
GQY29_RS09955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GQY29_RS09965	COG0187	DNA topoisomerase II activity
GQY29_RS09985	COG2040	homocysteine
GQY29_RS09990	COG0833	amino acid
GQY29_RS10010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GQY29_RS10020	COG3425	synthase
GQY29_RS10040	COG1272	protein, Hemolysin III
GQY29_RS10080	COG0438	transferase activity, transferring glycosyl groups
GQY29_RS10145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GQY29_RS10150	COG0686	Belongs to the AlaDH PNT family
GQY29_RS10155	COG0686	Belongs to the AlaDH PNT family
GQY29_RS10160	COG1473	amidohydrolase
GQY29_RS10165	COG1187	pseudouridine synthase activity
GQY29_RS10200	COG1131	(ABC) transporter
GQY29_RS10210	COG3279	Response regulator of the LytR AlgR family