locus-tag	class	description
STH8232_RS00010	COG0592	DNA-directed DNA polymerase activity
STH8232_RS00020	COG0012	GTP binding
STH8232_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
STH8232_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
STH8232_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STH8232_RS00085	COG2801	Transposase and inactivated derivatives
STH8232_RS00205	COG3942	CHAP domain
STH8232_RS00220	COG0436	Aminotransferase
STH8232_RS00235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STH8232_RS00245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
STH8232_RS00260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
STH8232_RS00280	COG2801	Transposase and inactivated derivatives
STH8232_RS00285	COG3942	CHAP domain
STH8232_RS00285	COG1388	LysM domain
STH8232_RS00290	COG0151	Belongs to the GarS family
STH8232_RS00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STH8232_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STH8232_RS00330	COG4550	Control of competence regulator ComK, YlbF/YmcA
STH8232_RS00370	COG2818	Glycosylase
STH8232_RS00385	COG1393	Belongs to the ArsC family
STH8232_RS00470	COG0582	viral genome integration into host DNA
STH8232_RS00500	COG0693	protein deglycase activity
STH8232_RS00515	COG2309	aminopeptidase activity
STH8232_RS00530	COG0431	NADPH-dependent FMN reductase
STH8232_RS00540	COG3634	alkyl hydroperoxide reductase activity
STH8232_RS00545	COG0450	alkyl hydroperoxide reductase
STH8232_RS00565	COG4463	regulation of RNA biosynthetic process
STH8232_RS00570	COG0542	response to heat
STH8232_RS00580	COG1686	Belongs to the peptidase S11 family
STH8232_RS00595	COG1045	serine acetyltransferase
STH8232_RS00605	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
STH8232_RS00620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STH8232_RS00645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
STH8232_RS00675	COG3340	Belongs to the peptidase S51 family
STH8232_RS00680	COG3321	synthase
STH8232_RS00680	COG0604	alcohol dehydrogenase
STH8232_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
STH8232_RS00685	COG0156	8-amino-7-oxononanoate synthase activity
STH8232_RS00700	COG1131	(ABC) transporter
STH8232_RS00720	COG2249	NAD(P)H dehydrogenase (quinone) activity
STH8232_RS00760	COG2814	Major facilitator Superfamily
STH8232_RS00765	COG0604	alcohol dehydrogenase
STH8232_RS00770	COG1959	2 iron, 2 sulfur cluster binding
STH8232_RS00835	COG1705	Flagellar rod assembly protein muramidase FlgJ
STH8232_RS00835	COG3942	CHAP domain
STH8232_RS00850	COG3830	Belongs to the UPF0237 family
STH8232_RS00865	COG1876	peptidase activity
STH8232_RS00900	COG0351	phosphomethylpyrimidine kinase
STH8232_RS00905	COG4720	Psort location CytoplasmicMembrane, score
STH8232_RS01005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
STH8232_RS01020	COG0668	transmembrane transport
STH8232_RS01035	COG0504	CTP synthase activity
STH8232_RS01045	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
STH8232_RS01055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
STH8232_RS01060	COG0737	Belongs to the 5'-nucleotidase family
STH8232_RS01095	COG3328	transposase activity
STH8232_RS01100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
STH8232_RS01130	COG1126	abc transporter atp-binding protein
STH8232_RS01135	COG0765	amino acid transport
STH8232_RS01140	COG1968	undecaprenyl-diphosphatase activity
STH8232_RS01150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STH8232_RS01160	COG0719	Fe-S assembly protein
STH8232_RS01165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
STH8232_RS01175	COG0719	Fe-S assembly protein
STH8232_RS01180	COG4166	transmembrane transport
STH8232_RS01185	COG0601	transmembrane transport
STH8232_RS01205	COG0444	Belongs to the ABC transporter superfamily
STH8232_RS01210	COG0444	Belongs to the ABC transporter superfamily
STH8232_RS01215	COG4608	Belongs to the ABC transporter superfamily
STH8232_RS01230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
STH8232_RS01245	COG1121	(ABC) transporter
STH8232_RS01250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STH8232_RS01260	COG2190	(PTS) system
STH8232_RS01260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STH8232_RS01260	COG1263	PTS System
STH8232_RS01265	COG2190	(PTS) system
STH8232_RS01265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STH8232_RS01265	COG1263	PTS System
STH8232_RS01295	COG4589	Belongs to the CDS family
STH8232_RS01310	COG4120	Belongs to the binding-protein-dependent transport system permease family
STH8232_RS01315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
STH8232_RS01315	COG1116	anion transmembrane transporter activity
STH8232_RS01360	COG0564	pseudouridine synthase activity
STH8232_RS01365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STH8232_RS01390	COG1349	DNA-binding transcription factor activity
STH8232_RS01410	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
STH8232_RS01425	COG3579	cysteine-type endopeptidase activity
STH8232_RS01430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STH8232_RS01450	COG0116	Belongs to the methyltransferase superfamily
STH8232_RS01460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
STH8232_RS01480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
STH8232_RS01505	COG1254	Belongs to the acylphosphatase family
STH8232_RS01510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STH8232_RS01550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
STH8232_RS01570	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
STH8232_RS01575	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
STH8232_RS01580	COG1187	pseudouridine synthase activity
STH8232_RS01590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STH8232_RS01595	COG0569	domain protein
STH8232_RS01605	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
STH8232_RS01610	COG0671	phosphoesterase, PA-phosphatase related
STH8232_RS01630	COG2274	protein secretion by the type I secretion system
STH8232_RS01635	COG2274	protein secretion by the type I secretion system
STH8232_RS01640	COG2274	protein secretion by the type I secretion system
STH8232_RS01690	COG0829	nickel cation binding
STH8232_RS01695	COG0310	cobalt ion transport
STH8232_RS01705	COG1122	ATPase activity
STH8232_RS01715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
STH8232_RS01735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STH8232_RS01740	COG1464	Belongs to the NlpA lipoprotein family
STH8232_RS01775	COG1122	ATPase activity
STH8232_RS01785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
STH8232_RS01795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STH8232_RS01810	COG0745	RESPONSE REGULATOR receiver
STH8232_RS01815	COG5002	protein histidine kinase activity
STH8232_RS01830	COG1484	DNA-dependent DNA replication
STH8232_RS01850	COG2801	Transposase and inactivated derivatives
STH8232_RS01875	COG3716	PTS system mannose fructose sorbose family IID component
STH8232_RS01880	COG3715	PTS system
STH8232_RS01890	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
STH8232_RS01895	COG0561	phosphatase activity
STH8232_RS01900	COG2252	PERMEase
STH8232_RS01905	COG0802	atpase or kinase
STH8232_RS01910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STH8232_RS01915	COG1316	TRANSCRIPTIONal
STH8232_RS01925	COG0195	Participates in both transcription termination and antitermination
STH8232_RS01930	COG2740	Nucleic-acid-binding protein implicated in transcription termination
STH8232_RS01950	COG1611	Belongs to the LOG family
STH8232_RS01970	COG2244	polysaccharide biosynthetic process
STH8232_RS01975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STH8232_RS01980	COG0626	cystathionine gamma-synthase activity
STH8232_RS01985	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
STH8232_RS02015	COG4471	UPF0298 protein
STH8232_RS02025	COG0559	Belongs to the binding-protein-dependent transport system permease family
STH8232_RS02045	COG0517	IMP dehydrogenase activity
STH8232_RS02060	COG1739	Uncharacterized protein family UPF0029
STH8232_RS02065	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
STH8232_RS02070	COG1040	competence protein
STH8232_RS02160	COG0527	aspartate kinase activity
STH8232_RS02165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STH8232_RS02170	COG1024	Enoyl-CoA hydratase
STH8232_RS02175	COG1846	Transcriptional regulator
STH8232_RS02195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
STH8232_RS02200	COG1028	Short-chain dehydrogenase reductase Sdr
STH8232_RS02205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STH8232_RS02220	COG0439	Biotin carboxylase
STH8232_RS02255	COG1349	DNA-binding transcription factor activity
STH8232_RS02260	COG1105	Belongs to the carbohydrate kinase PfkB family
STH8232_RS02265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STH8232_RS02265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STH8232_RS02265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STH8232_RS02270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STH8232_RS02275	COG0285	dihydrofolate synthase activity
STH8232_RS02285	COG1104	cysteine desulfurase activity
STH8232_RS02350	COG0488	(ABC) transporter
STH8232_RS02370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STH8232_RS02375	COG0242	peptide deformylase activity
STH8232_RS02435	COG1702	phosphate starvation-inducible protein PhoH
STH8232_RS02455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STH8232_RS02455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STH8232_RS02480	COG4122	O-methyltransferase activity
STH8232_RS02485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
STH8232_RS02520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STH8232_RS02525	COG0436	Aminotransferase
STH8232_RS02540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
STH8232_RS02545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
STH8232_RS02550	COG0726	polysaccharide deacetylase
STH8232_RS02565	COG2962	Rard protein
STH8232_RS02610	COG0356	it plays a direct role in the translocation of protons across the membrane
STH8232_RS02645	COG0772	Belongs to the SEDS family
STH8232_RS02665	COG0470	DNA polymerase III
STH8232_RS02670	COG1774	PSP1 C-terminal conserved region
STH8232_RS02675	COG4467	Involved in initiation control of chromosome replication
STH8232_RS02685	COG0004	ammonium transporteR
STH8232_RS02690	COG0347	Belongs to the P(II) protein family
STH8232_RS02695	COG1388	LysM domain
STH8232_RS02695	COG1705	Flagellar rod assembly protein muramidase FlgJ
STH8232_RS02750	COG1113	amino acid transport
STH8232_RS02760	COG2190	(PTS) system
STH8232_RS02760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STH8232_RS02760	COG1263	PTS System
STH8232_RS02795	COG0583	DNA-binding transcription factor activity
STH8232_RS02805	COG0564	pseudouridine synthase activity
STH8232_RS02825	COG0505	Belongs to the CarA family
STH8232_RS02880	COG0270	DNA (cytosine-5-)-methyltransferase activity
STH8232_RS03010	COG1396	sequence-specific DNA binding
STH8232_RS03015	COG0542	response to heat
STH8232_RS03040	COG3843	relaxase mobilization nuclease domain protein
STH8232_RS03075	COG1396	sequence-specific DNA binding
STH8232_RS03085	COG4974	Belongs to the 'phage' integrase family
STH8232_RS03100	COG0577	efflux transmembrane transporter activity
STH8232_RS03105	COG2801	Transposase and inactivated derivatives
STH8232_RS03165	COG3279	Response regulator of the LytR AlgR family
STH8232_RS03175	COG1131	(ABC) transporter
STH8232_RS03210	COG1187	pseudouridine synthase activity
STH8232_RS03215	COG1473	amidohydrolase
STH8232_RS03220	COG0686	Belongs to the AlaDH PNT family
STH8232_RS03225	COG0686	Belongs to the AlaDH PNT family
STH8232_RS03230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STH8232_RS03295	COG0438	transferase activity, transferring glycosyl groups
STH8232_RS03325	COG1272	protein, Hemolysin III
STH8232_RS03340	COG3425	synthase
STH8232_RS03350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
STH8232_RS03370	COG0833	amino acid
STH8232_RS03375	COG2040	homocysteine
STH8232_RS03395	COG0187	DNA topoisomerase II activity
STH8232_RS03405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STH8232_RS03425	COG0539	negative regulation of cytoplasmic translation
STH8232_RS03450	COG0673	inositol 2-dehydrogenase activity
STH8232_RS03465	COG0494	nUDIX hydrolase
STH8232_RS03470	COG0542	response to heat
STH8232_RS03475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
STH8232_RS03480	COG4703	Protein of unknown function (DUF1797)
STH8232_RS03485	COG0765	amino acid transport
STH8232_RS03525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STH8232_RS03530	COG0768	penicillin binding
STH8232_RS03535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
STH8232_RS03545	COG3711	transcriptional antiterminator
STH8232_RS03555	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
STH8232_RS03560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
STH8232_RS03565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
STH8232_RS03570	COG0237	dephospho-CoA kinase activity
STH8232_RS03575	COG2814	Major facilitator Superfamily
STH8232_RS03585	COG0557	exoribonuclease II activity
STH8232_RS03600	COG1185	polyribonucleotide nucleotidyltransferase activity
STH8232_RS03605	COG0006	proline dipeptidase activity
STH8232_RS03610	COG1609	Transcriptional regulator
STH8232_RS03640	COG1368	sulfuric ester hydrolase activity
STH8232_RS03645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
STH8232_RS03670	COG0287	Prephenate dehydrogenase
STH8232_RS03695	COG0077	Prephenate dehydratase
STH8232_RS03755	COG1518	maintenance of DNA repeat elements
STH8232_RS03760	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STH8232_RS03770	COG3689	TIGRFAM TIGR03943 family protein
STH8232_RS03775	COG0701	Predicted permease
STH8232_RS03780	COG2183	response to ionizing radiation
STH8232_RS03825	COG0826	peptidase U32
STH8232_RS03830	COG1268	BioY protein
STH8232_RS03840	COG4443	Transcriptional Coactivator p15 (PC4)
STH8232_RS03845	COG1914	H( )-stimulated, divalent metal cation uptake system
STH8232_RS03855	COG0494	nUDIX hydrolase
STH8232_RS03870	COG1388	LysM domain
STH8232_RS03870	COG1705	Flagellar rod assembly protein muramidase FlgJ
STH8232_RS03895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
STH8232_RS03925	COG4221	oxidoreductase activity
STH8232_RS03955	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
STH8232_RS03960	COG3620	sequence-specific DNA binding
STH8232_RS03980	COG1704	LemA family
STH8232_RS03985	COG0501	Belongs to the peptidase M48B family
STH8232_RS04010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
STH8232_RS04025	COG0783	Belongs to the Dps family
STH8232_RS04030	COG0735	belongs to the Fur family
STH8232_RS04035	COG4483	Protein conserved in bacteria
STH8232_RS04040	COG1940	carbohydrate kinase activity
STH8232_RS04045	COG1217	gtp-binding protein TYPA
STH8232_RS04080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STH8232_RS04100	COG3599	regulation of cell shape
STH8232_RS04135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STH8232_RS04140	COG0625	glutathione transferase activity
STH8232_RS04145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
STH8232_RS04150	COG1435	thymidine kinase activity
STH8232_RS04160	COG2890	protein-(glutamine-N5) methyltransferase activity
STH8232_RS04200	COG1132	(ABC) transporter
STH8232_RS04215	COG1696	Membrane protein involved in D-alanine export
STH8232_RS04225	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
STH8232_RS04235	COG2801	Transposase and inactivated derivatives
STH8232_RS04240	COG2801	Transposase and inactivated derivatives
STH8232_RS04260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STH8232_RS04265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STH8232_RS04285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STH8232_RS04290	COG4684	Psort location CytoplasmicMembrane, score
STH8232_RS04295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STH8232_RS04320	COG5002	protein histidine kinase activity
STH8232_RS04325	COG5002	protein histidine kinase activity
STH8232_RS04335	COG2801	Transposase and inactivated derivatives
STH8232_RS04355	COG0038	chloride channel
STH8232_RS04375	COG2801	Transposase and inactivated derivatives
STH8232_RS04395	COG2813	Specifically methylates the guanine in position
STH8232_RS04420	COG1744	ABC transporter substrate-binding protein PnrA-like
STH8232_RS04425	COG3845	ABC transporter
STH8232_RS04430	COG4603	Belongs to the binding-protein-dependent transport system permease family
STH8232_RS04435	COG1079	Belongs to the binding-protein-dependent transport system permease family
STH8232_RS04445	COG1199	ATP-dependent helicase activity
STH8232_RS04445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
STH8232_RS04455	COG0436	Aminotransferase
STH8232_RS04475	COG0251	oxidation-reduction process
STH8232_RS04485	COG0720	synthase
STH8232_RS04535	COG1278	Cold shock
STH8232_RS04550	COG2217	Heavy metal translocating P-type atpase
STH8232_RS04560	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STH8232_RS04570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
STH8232_RS04575	COG0626	cystathionine gamma-synthase activity
STH8232_RS04580	COG1045	serine acetyltransferase
STH8232_RS04600	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
STH8232_RS04605	COG4975	Glucose uptake
STH8232_RS04625	COG3443	Belongs to the bacterial solute-binding protein 9 family
STH8232_RS04625	COG0803	Belongs to the bacterial solute-binding protein 9 family
STH8232_RS04645	COG1705	Flagellar rod assembly protein muramidase FlgJ
STH8232_RS04645	COG3942	CHAP domain
STH8232_RS04660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
STH8232_RS04665	COG2824	Alkylphosphonate utilization operon protein PhnA
STH8232_RS04670	COG0765	amino acid transport
STH8232_RS04675	COG1126	abc transporter atp-binding protein
STH8232_RS04680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STH8232_RS04705	COG1064	alcohol dehydrogenase
STH8232_RS04715	COG3421	Type III restriction
STH8232_RS04720	COG2189	Belongs to the N(4) N(6)-methyltransferase family
STH8232_RS04725	COG2189	Belongs to the N(4) N(6)-methyltransferase family
STH8232_RS04775	COG0582	viral genome integration into host DNA
STH8232_RS04780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
STH8232_RS04780	COG0519	Catalyzes the synthesis of GMP from XMP
STH8232_RS04785	COG2188	Transcriptional regulator
STH8232_RS04795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STH8232_RS04805	COG1827	regulation of RNA biosynthetic process
STH8232_RS04815	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STH8232_RS04825	COG1940	carbohydrate kinase activity
STH8232_RS04830	COG0758	DNA mediated transformation
STH8232_RS04835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
STH8232_RS04895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
STH8232_RS04900	COG0010	Belongs to the arginase family
STH8232_RS04910	COG0028	Belongs to the TPP enzyme family
STH8232_RS04915	COG3527	Alpha-acetolactate decarboxylase
STH8232_RS04950	COG1230	cation diffusion facilitator family transporter
STH8232_RS04960	COG1063	alcohol dehydrogenase
STH8232_RS04985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STH8232_RS05010	COG1293	RNA-binding protein homologous to eukaryotic snRNP
STH8232_RS05040	COG0047	phosphoribosylformylglycinamidine synthase activity
STH8232_RS05050	COG0167	dihydroorotate dehydrogenase activity
STH8232_RS05060	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STH8232_RS05080	COG1337	RAMP superfamily
STH8232_RS05085	COG1567	CRISPR-associated RAMP protein, Csm4 family
STH8232_RS05105	COG0284	orotidine-5'-phosphate decarboxylase activity
STH8232_RS05120	COG3104	oligopeptide transport
STH8232_RS05135	COG0737	Belongs to the 5'-nucleotidase family
STH8232_RS05160	COG1115	amino acid carrier protein
STH8232_RS05170	COG2873	o-acetylhomoserine
STH8232_RS05200	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
STH8232_RS05205	COG0196	riboflavin kinase activity
STH8232_RS05210	COG1393	Belongs to the ArsC family
STH8232_RS05220	COG0483	inositol monophosphate 1-phosphatase activity
STH8232_RS05225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STH8232_RS05225	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
STH8232_RS05235	COG0573	inorganic phosphate transmembrane transporter activity
STH8232_RS05240	COG0581	inorganic phosphate transmembrane transporter activity
STH8232_RS05255	COG0704	Plays a role in the regulation of phosphate uptake
STH8232_RS05270	COG0095	Lipoate-protein ligase
STH8232_RS05285	COG0058	SHG alpha-glucan phosphorylase activity
STH8232_RS05290	COG1640	4-alpha-glucanotransferase
STH8232_RS05305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
STH8232_RS05310	COG0805	protein transport
STH8232_RS05320	COG2837	iron assimilation
STH8232_RS05325	COG2822	iron ion transport
STH8232_RS05335	COG1523	belongs to the glycosyl hydrolase 13 family
STH8232_RS05345	COG1523	belongs to the glycosyl hydrolase 13 family
STH8232_RS05385	COG0508	dehydrogenase complex catalyzes the overall conversion of
STH8232_RS05390	COG0508	dehydrogenase complex catalyzes the overall conversion of
STH8232_RS05390	COG0022	dehydrogenase e1 component
STH8232_RS05395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STH8232_RS05425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
STH8232_RS05435	COG4667	esterase of the alpha-beta hydrolase superfamily
STH8232_RS05465	COG0628	permease
STH8232_RS05470	COG0588	phosphoglycerate mutase activity
STH8232_RS05510	COG2801	Transposase and inactivated derivatives
STH8232_RS05535	COG0438	transferase activity, transferring glycosyl groups
STH8232_RS05540	COG0562	UDP-galactopyranose mutase
STH8232_RS05555	COG1216	Glycosyl transferase, family 2
STH8232_RS05560	COG1442	glycosyl transferase family 8
STH8232_RS05560	COG1216	Glycosyl transferase, family 2
STH8232_RS05570	COG0297	glycogen (starch) synthase activity
STH8232_RS05600	COG1316	TRANSCRIPTIONal
STH8232_RS05625	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
STH8232_RS05635	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
STH8232_RS05655	COG1573	uracil-dna glycosylase
STH8232_RS05690	COG0291	Belongs to the bacterial ribosomal protein bL35 family
STH8232_RS05720	COG0681	Belongs to the peptidase S26 family
STH8232_RS05730	COG0628	permease
STH8232_RS05735	COG1051	belongs to the nudix hydrolase family
STH8232_RS05740	COG2177	Part of the ABC transporter FtsEX involved in
STH8232_RS05745	COG2884	Cell division ATP-binding protein ftsE
STH8232_RS05750	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STH8232_RS05755	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
STH8232_RS05790	COG2348	transferase activity, transferring amino-acyl groups
STH8232_RS05800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
STH8232_RS05805	COG5002	protein histidine kinase activity
STH8232_RS05810	COG0745	RESPONSE REGULATOR receiver
STH8232_RS05815	COG1126	abc transporter atp-binding protein
STH8232_RS05820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STH8232_RS05825	COG0765	amino acid transport
STH8232_RS05830	COG0765	amino acid transport
STH8232_RS05855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STH8232_RS05910	COG3328	transposase activity
STH8232_RS05915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
STH8232_RS05920	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
STH8232_RS05920	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
STH8232_RS05930	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
STH8232_RS05935	COG1956	GAF domain-containing protein
STH8232_RS05940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
STH8232_RS05955	COG0335	large ribosomal subunit rRNA binding
STH8232_RS05960	COG0038	chloride channel
STH8232_RS05975	COG0716	FMN binding
STH8232_RS06035	COG0469	pyruvate kinase activity
STH8232_RS06085	COG0167	dihydroorotate dehydrogenase activity
STH8232_RS06095	COG0776	regulation of translation
STH8232_RS06105	COG2755	lipolytic protein G-D-S-L family
STH8232_RS06110	COG1307	EDD domain protein, DegV family
STH8232_RS06115	COG0497	DNA recombination
STH8232_RS06120	COG1438	arginine binding
STH8232_RS06125	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
STH8232_RS06150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STH8232_RS06170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
STH8232_RS06170	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
STH8232_RS06175	COG0300	oxidoreductase activity
STH8232_RS06190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
STH8232_RS06200	COG0772	Belongs to the SEDS family
STH8232_RS06215	COG0107	imidazoleglycerol-phosphate synthase activity
STH8232_RS06225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
STH8232_RS06235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
STH8232_RS06260	COG2801	Transposase and inactivated derivatives
STH8232_RS06295	COG0647	UMP catabolic process
STH8232_RS06305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
STH8232_RS06325	COG1088	dTDP-glucose 4,6-dehydratase activity
STH8232_RS06335	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
STH8232_RS06340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
STH8232_RS06355	COG2384	SAM-dependent methyltransferase
STH8232_RS06380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STH8232_RS06385	COG3442	glutamine amidotransferase
STH8232_RS06390	COG0392	lysyltransferase activity
STH8232_RS06390	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
STH8232_RS06405	COG0488	(ABC) transporter
STH8232_RS06415	COG0513	Belongs to the DEAD box helicase family
STH8232_RS06450	COG0372	Belongs to the citrate synthase family
STH8232_RS06455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
STH8232_RS06460	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
STH8232_RS06465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STH8232_RS06470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STH8232_RS06495	COG0346	lactoylglutathione lyase activity
STH8232_RS06500	COG3764	Sortase (surface protein transpeptidase)
STH8232_RS06520	COG0488	(ABC) transporter
STH8232_RS06550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
STH8232_RS06555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
STH8232_RS06555	COG1328	CTP reductase activity
STH8232_RS06585	COG1196	nuclear chromosome segregation
STH8232_RS06600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STH8232_RS06625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STH8232_RS06635	COG1011	Hydrolase
STH8232_RS06640	COG2197	response regulator
STH8232_RS06645	COG4585	Histidine kinase
STH8232_RS06655	COG1131	(ABC) transporter
STH8232_RS06705	COG1131	(ABC) transporter
STH8232_RS06725	COG0577	efflux transmembrane transporter activity
STH8232_RS06730	COG1136	(ABC) transporter
STH8232_RS06740	COG0745	RESPONSE REGULATOR receiver
STH8232_RS06755	COG0534	Mate efflux family protein
STH8232_RS06760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STH8232_RS06760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STH8232_RS06770	COG1482	cell wall glycoprotein biosynthetic process
STH8232_RS06775	COG1482	cell wall glycoprotein biosynthetic process
STH8232_RS06785	COG0531	amino acid
STH8232_RS06795	COG2514	catechol 2,3-dioxygenase activity
STH8232_RS06800	COG1959	2 iron, 2 sulfur cluster binding
STH8232_RS06810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STH8232_RS06815	COG0778	Nitroreductase
STH8232_RS06825	COG0656	L-ascorbic acid biosynthetic process
STH8232_RS06870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STH8232_RS06895	COG1280	lysine exporter protein (LysE YggA)
STH8232_RS06910	COG1216	Glycosyl transferase, family 2
STH8232_RS06910	COG1442	glycosyl transferase family 8
STH8232_RS06915	COG0577	efflux transmembrane transporter activity
STH8232_RS06960	COG1396	sequence-specific DNA binding
STH8232_RS06965	COG2801	Transposase and inactivated derivatives
STH8232_RS06980	COG0419	ATPase involved in DNA repair
STH8232_RS06985	COG0420	3'-5' exonuclease activity
STH8232_RS06990	COG3250	beta-galactosidase activity
STH8232_RS06995	COG2190	(PTS) system
STH8232_RS06995	COG2211	Major facilitator Superfamily
STH8232_RS07000	COG2017	converts alpha-aldose to the beta-anomer
STH8232_RS07005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STH8232_RS07020	COG1609	Transcriptional regulator
STH8232_RS07035	COG3064	Membrane
STH8232_RS07040	COG0488	(ABC) transporter
STH8232_RS07045	COG1132	(ABC) transporter
STH8232_RS07100	COG2197	response regulator
STH8232_RS07105	COG4585	Histidine kinase
STH8232_RS07115	COG2815	serine threonine protein kinase
STH8232_RS07115	COG0515	serine threonine protein kinase
STH8232_RS07125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STH8232_RS07125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
STH8232_RS07135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
STH8232_RS07150	COG0552	protein localization to endoplasmic reticulum
STH8232_RS07155	COG0561	phosphatase activity
STH8232_RS07160	COG0561	phosphatase activity
STH8232_RS07165	COG1725	Transcriptional regulator
STH8232_RS07170	COG1131	(ABC) transporter
STH8232_RS07180	COG4608	Belongs to the ABC transporter superfamily
STH8232_RS07185	COG0444	Belongs to the ABC transporter superfamily
STH8232_RS07190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STH8232_RS07195	COG0601	transmembrane transport
STH8232_RS07200	COG4166	transmembrane transport
STH8232_RS07210	COG4166	transmembrane transport
STH8232_RS07215	COG4608	Belongs to the ABC transporter superfamily
STH8232_RS07220	COG4608	Belongs to the ABC transporter superfamily
STH8232_RS07225	COG0084	hydrolase, TatD family'
STH8232_RS07230	COG2223	nitrite transmembrane transporter activity
STH8232_RS07235	COG2801	Transposase and inactivated derivatives
STH8232_RS07245	COG0280	phosphate acetyltransferase
STH8232_RS07250	COG0564	pseudouridine synthase activity
STH8232_RS07260	COG2357	RelA SpoT domain protein
STH8232_RS07275	COG1104	cysteine desulfurase activity
STH8232_RS07290	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
STH8232_RS07325	COG1215	transferase activity, transferring glycosyl groups
STH8232_RS07340	COG1442	glycosyl transferase family 8
STH8232_RS07340	COG1216	Glycosyl transferase, family 2
STH8232_RS07355	COG0463	Glycosyl transferase, family 2
STH8232_RS07360	COG1091	dTDP-4-dehydrorhamnose reductase activity
STH8232_RS07370	COG0463	Glycosyl transferase, family 2
STH8232_RS07375	COG2151	metal-sulfur cluster biosynthetic enzyme
STH8232_RS07380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STH8232_RS07385	COG0358	DNA primase activity
STH8232_RS07395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STH8232_RS07400	COG0436	Aminotransferase
STH8232_RS07405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STH8232_RS07410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STH8232_RS07415	COG1051	belongs to the nudix hydrolase family
STH8232_RS07440	COG0765	amino acid transport
STH8232_RS07445	COG1126	abc transporter atp-binding protein
STH8232_RS07460	COG1187	pseudouridine synthase activity
STH8232_RS07500	COG0560	Phosphoserine phosphatase
STH8232_RS07510	COG0187	DNA topoisomerase II activity
STH8232_RS07520	COG1346	cytolysis
STH8232_RS07525	COG1380	Effector of murein hydrolase LrgA
STH8232_RS07535	COG1393	Belongs to the ArsC family
STH8232_RS07545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
STH8232_RS07585	COG1177	transmembrane transport
STH8232_RS07590	COG1176	ABC-type spermidine putrescine transport system, permease component I
STH8232_RS07630	COG0531	amino acid
STH8232_RS07635	COG0285	dihydrofolate synthase activity
STH8232_RS07640	COG1837	Belongs to the UPF0109 family
STH8232_RS07650	COG3615	Tellurite resistance protein tehB
STH8232_RS07650	COG0500	methyltransferase
STH8232_RS07660	COG0708	Exodeoxyribonuclease III
STH8232_RS07675	COG1597	lipid kinase activity
STH8232_RS07685	COG4708	membrane
STH8232_RS07695	COG0024	Methionine aminopeptidase
STH8232_RS07700	COG4109	DRTGG domain
STH8232_RS07710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
STH8232_RS07715	COG0658	competence protein
STH8232_RS07715	COG2333	competence protein COMEC
STH8232_RS07720	COG1596	polysaccharide export
STH8232_RS07720	COG1555	photosystem II stabilization
STH8232_RS07745	COG1129	ABC transporter
STH8232_RS07745	COG0842	Transport permease protein
STH8232_RS07765	COG0204	Acyl-transferase
STH8232_RS07770	COG0726	polysaccharide deacetylase
STH8232_RS07775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
STH8232_RS07785	COG0513	Belongs to the DEAD box helicase family
STH8232_RS07805	COG1396	sequence-specific DNA binding
STH8232_RS07825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STH8232_RS07840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STH8232_RS07845	COG1126	abc transporter atp-binding protein
STH8232_RS07850	COG0765	amino acid transport
STH8232_RS07855	COG0765	amino acid transport
STH8232_RS07870	COG2217	Heavy metal translocating P-type atpase
STH8232_RS07880	COG0159	tryptophan synthase activity
STH8232_RS07890	COG0135	phosphoribosylanthranilate isomerase activity
STH8232_RS07905	COG0512	Glutamine amidotransferase of anthranilate synthase
STH8232_RS07910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STH8232_RS07915	COG0287	Prephenate dehydrogenase
STH8232_RS07915	COG1605	Chorismate mutase
STH8232_RS07925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STH8232_RS07950	COG2176	DNA-directed DNA polymerase activity
STH8232_RS07960	COG2151	metal-sulfur cluster biosynthetic enzyme
STH8232_RS07970	COG2081	HI0933 family
STH8232_RS07995	COG1131	(ABC) transporter
STH8232_RS08000	COG0537	adenosine 5'-monophosphoramidase activity
STH8232_RS08030	COG2226	methyltransferase
STH8232_RS08035	COG0799	negative regulation of ribosome biogenesis
STH8232_RS08040	COG1713	HD superfamily hydrolase involved in NAD metabolism
STH8232_RS08045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
STH8232_RS08050	COG1534	Rna-binding protein
STH8232_RS08055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STH8232_RS08060	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
STH8232_RS08095	COG2723	6-phospho-beta-galactosidase activity
STH8232_RS08110	COG1335	isochorismatase
STH8232_RS08120	COG0436	Aminotransferase
STH8232_RS08125	COG0589	response to stress
STH8232_RS08140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STH8232_RS08145	COG1253	flavin adenine dinucleotide binding
STH8232_RS08150	COG1119	ATPase activity
STH8232_RS08155	COG0025	NhaP-type Na H and K H
STH8232_RS08165	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
STH8232_RS08170	COG1242	4 iron, 4 sulfur cluster binding
STH8232_RS08175	COG3480	Lon protease (S16) C-terminal proteolytic domain
STH8232_RS08180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
STH8232_RS08185	COG0742	ribosomal rna small subunit methyltransferase
STH8232_RS08190	COG0492	ferredoxin-NADP+ reductase activity
STH8232_RS08200	COG1126	abc transporter atp-binding protein
STH8232_RS08210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STH8232_RS08225	COG1882	Formate acetyltransferase
STH8232_RS08250	COG0390	transport system, permease component
STH8232_RS08255	COG4619	ABC transporter
STH8232_RS08260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
STH8232_RS08275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STH8232_RS08350	COG3290	protein histidine kinase activity
STH8232_RS08360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STH8232_RS08370	COG1132	(ABC) transporter
STH8232_RS08375	COG1132	(ABC) transporter
STH8232_RS08395	COG4470	Protein conserved in bacteria
STH8232_RS08400	COG0737	Belongs to the 5'-nucleotidase family
STH8232_RS08405	COG0513	Belongs to the DEAD box helicase family
STH8232_RS08415	COG0768	penicillin binding
STH8232_RS08455	COG3152	Membrane
STH8232_RS08465	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
STH8232_RS08480	COG4152	abc transporter atp-binding protein
STH8232_RS08485	COG1811	Na channel or pump
STH8232_RS08525	COG0561	phosphatase activity
STH8232_RS08530	COG0252	asparaginase activity
STH8232_RS08535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STH8232_RS08540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
STH8232_RS08550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STH8232_RS08555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STH8232_RS08570	COG1482	cell wall glycoprotein biosynthetic process
STH8232_RS08575	COG1940	carbohydrate kinase activity
STH8232_RS08580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STH8232_RS08580	COG2190	(PTS) system
STH8232_RS08580	COG1263	PTS System
STH8232_RS08585	COG1621	beta-fructofuranosidase activity
STH8232_RS08590	COG1609	Transcriptional regulator
STH8232_RS08610	COG2131	deaminase
STH8232_RS08615	COG0006	proline dipeptidase activity
STH8232_RS08630	COG1131	(ABC) transporter
STH8232_RS08705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STH8232_RS08705	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STH8232_RS08730	COG0681	Belongs to the peptidase S26 family
STH8232_RS08735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
STH8232_RS08745	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
STH8232_RS08755	COG0456	acetyltransferase
STH8232_RS08760	COG1214	PFAM Peptidase M22, glycoprotease
STH8232_RS08780	COG0174	glutamine synthetase
STH8232_RS08785	COG0789	Transcriptional regulator
STH8232_RS08825	COG2801	Transposase and inactivated derivatives
STH8232_RS08860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
STH8232_RS08895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
STH8232_RS08905	COG0084	hydrolase, TatD family'
STH8232_RS08910	COG1832	CoA-binding protein
STH8232_RS08915	COG3118	belongs to the thioredoxin family
STH8232_RS08975	COG0706	membrane insertase activity
STH8232_RS09040	COG0756	dUTP diphosphatase activity
STH8232_RS09075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STH8232_RS09080	COG0457	Tetratricopeptide repeat
STH8232_RS09080	COG0705	Rhomboid family
STH8232_RS09085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STH8232_RS09105	COG2226	methyltransferase
STH8232_RS09130	COG0425	Belongs to the sulfur carrier protein TusA family
STH8232_RS09135	COG2391	methyltransferase activity
STH8232_RS09140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STH8232_RS09145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STH8232_RS09155	COG1363	Peptidase, m42
STH8232_RS09160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
STH8232_RS09165	COG1266	CAAX protease self-immunity
STH8232_RS09225	COG1459	type II secretion system
STH8232_RS09230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STH8232_RS09265	COG0440	acetolactate synthase activity
STH8232_RS09270	COG0028	Belongs to the TPP enzyme family
STH8232_RS09275	COG0129	dihydroxy-acid dehydratase activity
STH8232_RS09280	COG1461	Dihydroxyacetone kinase
STH8232_RS09290	COG0534	Mate efflux family protein
STH8232_RS09315	COG1012	belongs to the aldehyde dehydrogenase family
STH8232_RS09315	COG1454	alcohol dehydrogenase
STH8232_RS09320	COG1012	belongs to the aldehyde dehydrogenase family
STH8232_RS09320	COG1454	alcohol dehydrogenase
STH8232_RS09325	COG1012	belongs to the aldehyde dehydrogenase family
STH8232_RS09325	COG1454	alcohol dehydrogenase
STH8232_RS09330	COG3590	peptidase
STH8232_RS09335	COG0366	Alpha amylase catalytic
STH8232_RS09340	COG0366	Alpha amylase catalytic
STH8232_RS09345	COG0366	Alpha amylase catalytic
STH8232_RS09355	COG1609	Transcriptional regulator
STH8232_RS09360	COG2188	Transcriptional regulator
STH8232_RS09365	COG4475	Protein of unknown function (DUF436)
STH8232_RS09395	COG3328	transposase activity
STH8232_RS09440	COG3328	transposase activity
STH8232_RS09445	COG0582	viral genome integration into host DNA
STH8232_RS09450	COG0191	fructose-bisphosphate aldolase activity
STH8232_RS09510	COG0201	protein transport
STH8232_RS09655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
STH8232_RS09665	COG3328	transposase activity
STH8232_RS09680	COG1132	(ABC) transporter
STH8232_RS09685	COG1396	sequence-specific DNA binding
STH8232_RS09695	COG1132	(ABC) transporter
STH8232_RS09730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
STH8232_RS09770	COG0602	queuosine metabolic process
STH8232_RS09780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STH8232_RS09805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
STH8232_RS09815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STH8232_RS09840	COG2261	transglycosylase associated protein
STH8232_RS09860	COG3237	CsbD-like
STH8232_RS09865	COG1695	Transcriptional regulator
STH8232_RS09880	COG1511	domain protein
STH8232_RS09880	COG1511	domain protein
STH8232_RS09890	COG3759	membrane
STH8232_RS09905	COG0305	Participates in initiation and elongation during chromosome replication
STH8232_RS09925	COG0494	nUDIX hydrolase
STH8232_RS09940	COG0741	lytic transglycosylase activity
STH8232_RS09945	COG1388	LysM domain
STH8232_RS09945	COG3584	3D domain protein
STH8232_RS09950	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
STH8232_RS09965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
STH8232_RS09975	COG0612	Peptidase, M16
STH8232_RS10005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STH8232_RS10010	COG0488	(ABC) transporter
STH8232_RS10045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STH8232_RS10050	COG1475	DNA binding
STH8232_RS10060	COG0588	phosphoglycerate mutase activity
STH8232_RS10105	COG4166	transmembrane transport
STH8232_RS10110	COG4166	transmembrane transport