locus-tag	class	description
STU_RS09465	COG0592	DNA-directed DNA polymerase activity
STU_RS09475	COG0012	GTP binding
STU_RS09485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
STU_RS09490	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
STU_RS09520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STU_RS09545	COG2801	Transposase and inactivated derivatives
STU_RS09665	COG3942	CHAP domain
STU_RS09685	COG0436	Aminotransferase
STU_RS09700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STU_RS09705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
STU_RS09710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
STU_RS09725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
STU_RS09745	COG2801	Transposase and inactivated derivatives
STU_RS09755	COG0151	Belongs to the GarS family
STU_RS09760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STU_RS09780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STU_RS09790	COG0018	arginyl-trna synthetase
STU_RS09800	COG4550	Control of competence regulator ComK, YlbF/YmcA
STU_RS09805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
STU_RS09840	COG2818	Glycosylase
STU_RS09845	COG1546	Belongs to the CinA family
STU_RS09845	COG1058	Belongs to the CinA family
STU_RS09850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
STU_RS09855	COG1393	Belongs to the ArsC family
STU_RS09940	COG2176	DNA-directed DNA polymerase activity
STU_RS09945	COG2309	aminopeptidase activity
STU_RS09960	COG0431	NADPH-dependent FMN reductase
STU_RS09970	COG2801	Transposase and inactivated derivatives
STU_RS09990	COG1619	proteins homologs of microcin C7 resistance protein MccF
STU_RS10015	COG4463	regulation of RNA biosynthetic process
STU_RS10020	COG0542	response to heat
STU_RS10030	COG1686	Belongs to the peptidase S11 family
STU_RS10045	COG1045	serine acetyltransferase
STU_RS10055	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
STU_RS10065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STU_RS10090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
STU_RS10145	COG1705	Flagellar rod assembly protein muramidase FlgJ
STU_RS10145	COG3942	CHAP domain
STU_RS10160	COG3830	Belongs to the UPF0237 family
STU_RS10175	COG1876	peptidase activity
STU_RS10195	COG0443	Heat shock 70 kDa protein
STU_RS10210	COG0351	phosphomethylpyrimidine kinase
STU_RS10310	COG4166	transmembrane transport
STU_RS10330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
STU_RS10345	COG0668	transmembrane transport
STU_RS10360	COG0504	CTP synthase activity
STU_RS10370	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
STU_RS10380	COG1385	rRNA (uridine-N3-)-methyltransferase activity
STU_RS10385	COG0737	Belongs to the 5'-nucleotidase family
STU_RS10395	COG0737	Belongs to the 5'-nucleotidase family
STU_RS10400	COG0737	Belongs to the 5'-nucleotidase family
STU_RS10440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
STU_RS10470	COG1126	abc transporter atp-binding protein
STU_RS10475	COG0765	amino acid transport
STU_RS10480	COG1968	undecaprenyl-diphosphatase activity
STU_RS10485	COG4862	establishment of competence for transformation
STU_RS10490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STU_RS10500	COG0719	Fe-S assembly protein
STU_RS10505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
STU_RS10515	COG0719	Fe-S assembly protein
STU_RS10525	COG0601	transmembrane transport
STU_RS10540	COG0444	Belongs to the ABC transporter superfamily
STU_RS10545	COG0444	Belongs to the ABC transporter superfamily
STU_RS10550	COG4608	Belongs to the ABC transporter superfamily
STU_RS10560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
STU_RS10565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
STU_RS10590	COG1121	(ABC) transporter
STU_RS10595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STU_RS10605	COG1263	PTS System
STU_RS10605	COG2190	(PTS) system
STU_RS10605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STU_RS10610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STU_RS10610	COG2190	(PTS) system
STU_RS10610	COG1263	PTS System
STU_RS10615	COG2190	(PTS) system
STU_RS10615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STU_RS10615	COG1263	PTS System
STU_RS10645	COG4589	Belongs to the CDS family
STU_RS10660	COG4120	Belongs to the binding-protein-dependent transport system permease family
STU_RS10665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
STU_RS10665	COG1116	anion transmembrane transporter activity
STU_RS10690	COG2801	Transposase and inactivated derivatives
STU_RS10705	COG0564	pseudouridine synthase activity
STU_RS10710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STU_RS10735	COG1349	DNA-binding transcription factor activity
STU_RS10765	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
STU_RS10780	COG3579	cysteine-type endopeptidase activity
STU_RS10785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STU_RS10805	COG0116	Belongs to the methyltransferase superfamily
STU_RS10815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
STU_RS10835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
STU_RS10860	COG1254	Belongs to the acylphosphatase family
STU_RS10865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STU_RS10905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
STU_RS10910	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
STU_RS10930	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
STU_RS10935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
STU_RS10940	COG1187	pseudouridine synthase activity
STU_RS10950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STU_RS10955	COG0569	domain protein
STU_RS10970	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
STU_RS10975	COG0671	phosphoesterase, PA-phosphatase related
STU_RS10990	COG2274	protein secretion by the type I secretion system
STU_RS10995	COG2274	protein secretion by the type I secretion system
STU_RS11000	COG2274	protein secretion by the type I secretion system
STU_RS11005	COG2274	protein secretion by the type I secretion system
STU_RS11055	COG0829	nickel cation binding
STU_RS11060	COG0310	cobalt ion transport
STU_RS11070	COG1122	ATPase activity
STU_RS11075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STU_RS11080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
STU_RS11100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STU_RS11105	COG1464	Belongs to the NlpA lipoprotein family
STU_RS11115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
STU_RS11125	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
STU_RS11150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
STU_RS11160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STU_RS11175	COG0745	RESPONSE REGULATOR receiver
STU_RS11180	COG5002	protein histidine kinase activity
STU_RS11195	COG1484	DNA-dependent DNA replication
STU_RS11210	COG1132	(ABC) transporter
STU_RS11220	COG3328	transposase activity
STU_RS11235	COG3716	PTS system mannose fructose sorbose family IID component
STU_RS11240	COG3715	PTS system
STU_RS11250	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
STU_RS11255	COG0561	phosphatase activity
STU_RS11260	COG2252	PERMEase
STU_RS11265	COG0802	atpase or kinase
STU_RS11270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STU_RS11275	COG1316	TRANSCRIPTIONal
STU_RS11285	COG0195	Participates in both transcription termination and antitermination
STU_RS11290	COG2740	Nucleic-acid-binding protein implicated in transcription termination
STU_RS11300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
STU_RS11310	COG1611	Belongs to the LOG family
STU_RS11330	COG2244	polysaccharide biosynthetic process
STU_RS11340	COG0626	cystathionine gamma-synthase activity
STU_RS11345	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
STU_RS11375	COG4471	UPF0298 protein
STU_RS11385	COG0559	Belongs to the binding-protein-dependent transport system permease family
STU_RS11405	COG0517	IMP dehydrogenase activity
STU_RS11420	COG1739	Uncharacterized protein family UPF0029
STU_RS11425	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
STU_RS11430	COG1040	competence protein
STU_RS11515	COG2502	aspartate--ammonia ligase
STU_RS11520	COG0527	aspartate kinase activity
STU_RS11525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STU_RS11530	COG1024	Enoyl-CoA hydratase
STU_RS11535	COG1846	Transcriptional regulator
STU_RS11540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
STU_RS11555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
STU_RS11560	COG1028	Short-chain dehydrogenase reductase Sdr
STU_RS11565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STU_RS11580	COG0439	Biotin carboxylase
STU_RS11590	COG0825	malonyl-CoA metabolic process
STU_RS11620	COG1349	DNA-binding transcription factor activity
STU_RS11625	COG1105	Belongs to the carbohydrate kinase PfkB family
STU_RS11635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STU_RS11640	COG0285	dihydrofolate synthase activity
STU_RS11650	COG1104	cysteine desulfurase activity
STU_RS11720	COG0488	(ABC) transporter
STU_RS11740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STU_RS11745	COG0242	peptide deformylase activity
STU_RS11770	COG0528	UMP kinase activity
STU_RS11800	COG1702	phosphate starvation-inducible protein PhoH
STU_RS11825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STU_RS11825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STU_RS11830	COG0583	DNA-binding transcription factor activity
STU_RS11850	COG4122	O-methyltransferase activity
STU_RS11855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
STU_RS11880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STU_RS11885	COG0436	Aminotransferase
STU_RS11895	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
STU_RS11900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
STU_RS11905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
STU_RS11910	COG0726	polysaccharide deacetylase
STU_RS11925	COG2962	Rard protein
STU_RS11955	COG0525	valine-tRNA ligase activity
STU_RS11965	COG0356	it plays a direct role in the translocation of protons across the membrane
STU_RS11990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
STU_RS11995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
STU_RS12000	COG0772	Belongs to the SEDS family
STU_RS12020	COG0470	DNA polymerase III
STU_RS12025	COG1774	PSP1 C-terminal conserved region
STU_RS12030	COG4467	Involved in initiation control of chromosome replication
STU_RS12040	COG0004	ammonium transporteR
STU_RS12045	COG0347	Belongs to the P(II) protein family
STU_RS12050	COG1388	LysM domain
STU_RS12050	COG1705	Flagellar rod assembly protein muramidase FlgJ
STU_RS12105	COG1113	amino acid transport
STU_RS12115	COG1263	PTS System
STU_RS12115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STU_RS12115	COG2190	(PTS) system
STU_RS12150	COG0583	DNA-binding transcription factor activity
STU_RS12160	COG0564	pseudouridine synthase activity
STU_RS12180	COG0505	Belongs to the CarA family
STU_RS12235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
STU_RS12250	COG3279	Response regulator of the LytR AlgR family
STU_RS12260	COG1131	(ABC) transporter
STU_RS12270	COG1054	Belongs to the UPF0176 family
STU_RS12295	COG1187	pseudouridine synthase activity
STU_RS12300	COG1473	amidohydrolase
STU_RS12305	COG0686	Belongs to the AlaDH PNT family
STU_RS12310	COG0686	Belongs to the AlaDH PNT family
STU_RS12315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STU_RS12345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
STU_RS12380	COG0438	transferase activity, transferring glycosyl groups
STU_RS12410	COG1272	protein, Hemolysin III
STU_RS12420	COG3425	synthase
STU_RS12425	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
STU_RS12430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
STU_RS12450	COG0833	amino acid
STU_RS12455	COG2040	homocysteine
STU_RS12475	COG0187	DNA topoisomerase II activity
STU_RS12485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STU_RS12505	COG0539	negative regulation of cytoplasmic translation
STU_RS12540	COG0673	inositol 2-dehydrogenase activity
STU_RS12560	COG0494	nUDIX hydrolase
STU_RS12565	COG0542	response to heat
STU_RS12570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
STU_RS12575	COG4703	Protein of unknown function (DUF1797)
STU_RS12580	COG0765	amino acid transport
STU_RS12615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
STU_RS12620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STU_RS12625	COG0768	penicillin binding
STU_RS12630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
STU_RS12640	COG3711	transcriptional antiterminator
STU_RS12650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
STU_RS12655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
STU_RS12660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
STU_RS12665	COG0237	dephospho-CoA kinase activity
STU_RS12670	COG2814	Major facilitator Superfamily
STU_RS12680	COG0557	exoribonuclease II activity
STU_RS12695	COG1185	polyribonucleotide nucleotidyltransferase activity
STU_RS12700	COG0006	proline dipeptidase activity
STU_RS12705	COG1609	Transcriptional regulator
STU_RS12730	COG1368	sulfuric ester hydrolase activity
STU_RS12735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
STU_RS12760	COG0287	Prephenate dehydrogenase
STU_RS12775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
STU_RS12785	COG0077	Prephenate dehydratase
STU_RS12840	COG1518	maintenance of DNA repeat elements
STU_RS12845	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STU_RS12855	COG3689	TIGRFAM TIGR03943 family protein
STU_RS12860	COG0701	Predicted permease
STU_RS12865	COG2183	response to ionizing radiation
STU_RS12880	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
STU_RS12885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
STU_RS12910	COG0826	peptidase U32
STU_RS12915	COG1268	BioY protein
STU_RS12925	COG4443	Transcriptional Coactivator p15 (PC4)
STU_RS12930	COG1914	H( )-stimulated, divalent metal cation uptake system
STU_RS12940	COG0494	nUDIX hydrolase
STU_RS12955	COG1705	Flagellar rod assembly protein muramidase FlgJ
STU_RS12955	COG1388	LysM domain
STU_RS12975	COG0406	alpha-ribazole phosphatase activity
STU_RS12980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
STU_RS13010	COG4221	oxidoreductase activity
STU_RS13015	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STU_RS13060	COG1704	LemA family
STU_RS13065	COG0501	Belongs to the peptidase M48B family
STU_RS13080	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
STU_RS13090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
STU_RS13100	COG0783	Belongs to the Dps family
STU_RS13105	COG0735	belongs to the Fur family
STU_RS13115	COG4483	Protein conserved in bacteria
STU_RS13120	COG1940	carbohydrate kinase activity
STU_RS13125	COG1217	gtp-binding protein TYPA
STU_RS13150	COG0849	cell division
STU_RS13160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STU_RS13180	COG3599	regulation of cell shape
STU_RS13215	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STU_RS13220	COG0625	glutathione transferase activity
STU_RS13225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
STU_RS13230	COG1435	thymidine kinase activity
STU_RS13240	COG2890	protein-(glutamine-N5) methyltransferase activity
STU_RS13250	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
STU_RS13270	COG1132	(ABC) transporter
STU_RS13285	COG1696	Membrane protein involved in D-alanine export
STU_RS13295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
STU_RS13300	COG2801	Transposase and inactivated derivatives
STU_RS13305	COG2801	Transposase and inactivated derivatives
STU_RS13320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STU_RS13325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STU_RS13345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STU_RS13350	COG4684	Psort location CytoplasmicMembrane, score
STU_RS13355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STU_RS13365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
STU_RS13380	COG5002	protein histidine kinase activity
STU_RS13385	COG5002	protein histidine kinase activity
STU_RS13390	COG2801	Transposase and inactivated derivatives
STU_RS13410	COG2813	Specifically methylates the guanine in position
STU_RS13435	COG1744	ABC transporter substrate-binding protein PnrA-like
STU_RS13440	COG3845	ABC transporter
STU_RS13445	COG4603	Belongs to the binding-protein-dependent transport system permease family
STU_RS13450	COG1079	Belongs to the binding-protein-dependent transport system permease family
STU_RS13470	COG0436	Aminotransferase
STU_RS13475	COG0017	Asparaginyl-tRNA synthetase
STU_RS13495	COG0251	oxidation-reduction process
STU_RS13505	COG0720	synthase
STU_RS13555	COG1278	Cold shock
STU_RS13565	COG3328	transposase activity
STU_RS13570	COG2217	Heavy metal translocating P-type atpase
STU_RS13585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
STU_RS13590	COG0626	cystathionine gamma-synthase activity
STU_RS13595	COG1045	serine acetyltransferase
STU_RS13600	COG3328	transposase activity
STU_RS13620	COG4975	Glucose uptake
STU_RS13625	COG4716	Myosin-crossreactive antigen
STU_RS13640	COG0803	Belongs to the bacterial solute-binding protein 9 family
STU_RS13640	COG3443	Belongs to the bacterial solute-binding protein 9 family
STU_RS13685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
STU_RS13690	COG2824	Alkylphosphonate utilization operon protein PhnA
STU_RS13695	COG0765	amino acid transport
STU_RS13700	COG1126	abc transporter atp-binding protein
STU_RS13705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STU_RS13720	COG1064	alcohol dehydrogenase
STU_RS13725	COG1064	alcohol dehydrogenase
STU_RS13730	COG1064	alcohol dehydrogenase
STU_RS13740	COG3421	Type III restriction
STU_RS13745	COG2189	Belongs to the N(4) N(6)-methyltransferase family
STU_RS13750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
STU_RS13750	COG0519	Catalyzes the synthesis of GMP from XMP
STU_RS13755	COG2188	Transcriptional regulator
STU_RS13765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STU_RS13775	COG1827	regulation of RNA biosynthetic process
STU_RS13785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STU_RS13795	COG1940	carbohydrate kinase activity
STU_RS13800	COG0758	DNA mediated transformation
STU_RS13805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
STU_RS13810	COG2801	Transposase and inactivated derivatives
STU_RS13835	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
STU_RS13850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
STU_RS13860	COG0481	GTPase activity
STU_RS13880	COG1396	sequence-specific DNA binding
STU_RS13890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
STU_RS13895	COG0010	Belongs to the arginase family
STU_RS13905	COG0028	Belongs to the TPP enzyme family
STU_RS13910	COG3527	Alpha-acetolactate decarboxylase
STU_RS13945	COG1230	cation diffusion facilitator family transporter
STU_RS13955	COG1063	alcohol dehydrogenase
STU_RS14000	COG0534	Mate efflux family protein
STU_RS14010	COG1293	RNA-binding protein homologous to eukaryotic snRNP
STU_RS14020	COG0047	phosphoribosylformylglycinamidine synthase activity
STU_RS14030	COG0167	dihydroorotate dehydrogenase activity
STU_RS14045	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STU_RS14065	COG1337	RAMP superfamily
STU_RS14070	COG1567	CRISPR-associated RAMP protein, Csm4 family
STU_RS14090	COG0284	orotidine-5'-phosphate decarboxylase activity
STU_RS14105	COG3104	oligopeptide transport
STU_RS14115	COG0154	amidase activity
STU_RS14135	COG0737	Belongs to the 5'-nucleotidase family
STU_RS14150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
STU_RS14155	COG1115	amino acid carrier protein
STU_RS14160	COG0210	DNA helicase
STU_RS14165	COG2873	o-acetylhomoserine
STU_RS14195	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
STU_RS14200	COG0196	riboflavin kinase activity
STU_RS14205	COG1393	Belongs to the ArsC family
STU_RS14215	COG0483	inositol monophosphate 1-phosphatase activity
STU_RS14220	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
STU_RS14220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STU_RS14230	COG0573	inorganic phosphate transmembrane transporter activity
STU_RS14235	COG0581	inorganic phosphate transmembrane transporter activity
STU_RS14250	COG0704	Plays a role in the regulation of phosphate uptake
STU_RS14260	COG4974	Belongs to the 'phage' integrase family
STU_RS14265	COG0095	Lipoate-protein ligase
STU_RS14280	COG0058	SHG alpha-glucan phosphorylase activity
STU_RS14285	COG1640	4-alpha-glucanotransferase
STU_RS14290	COG1609	Transcriptional regulator
STU_RS14310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
STU_RS14315	COG0805	protein transport
STU_RS14320	COG0672	)-iron permease
STU_RS14325	COG2837	iron assimilation
STU_RS14330	COG2822	iron ion transport
STU_RS14335	COG4607	ABC-type enterochelin transport system periplasmic component
STU_RS14340	COG4604	ABC transporter, ATP-binding protein
STU_RS14345	COG4605	iron ion homeostasis
STU_RS14350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
STU_RS14360	COG1523	belongs to the glycosyl hydrolase 13 family
STU_RS14365	COG1523	belongs to the glycosyl hydrolase 13 family
STU_RS14410	COG0508	dehydrogenase complex catalyzes the overall conversion of
STU_RS14415	COG0022	dehydrogenase e1 component
STU_RS14415	COG0508	dehydrogenase complex catalyzes the overall conversion of
STU_RS14420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STU_RS14450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
STU_RS14460	COG4667	esterase of the alpha-beta hydrolase superfamily
STU_RS14485	COG2723	6-phospho-beta-galactosidase activity
STU_RS14500	COG0628	permease
STU_RS14585	COG0438	transferase activity, transferring glycosyl groups
STU_RS14610	COG1045	serine acetyltransferase
STU_RS14620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
STU_RS14650	COG1316	TRANSCRIPTIONal
STU_RS14670	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
STU_RS14680	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
STU_RS14705	COG1573	uracil-dna glycosylase
STU_RS14740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
STU_RS14745	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
STU_RS14770	COG0681	Belongs to the peptidase S26 family
STU_RS14780	COG0628	permease
STU_RS14785	COG1051	belongs to the nudix hydrolase family
STU_RS14790	COG2177	Part of the ABC transporter FtsEX involved in
STU_RS14795	COG2884	Cell division ATP-binding protein ftsE
STU_RS14800	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STU_RS14805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
STU_RS14840	COG2348	transferase activity, transferring amino-acyl groups
STU_RS14845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
STU_RS14850	COG5002	protein histidine kinase activity
STU_RS14855	COG0745	RESPONSE REGULATOR receiver
STU_RS14860	COG1126	abc transporter atp-binding protein
STU_RS14865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STU_RS14870	COG0765	amino acid transport
STU_RS14875	COG0765	amino acid transport
STU_RS14890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
STU_RS14900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STU_RS14910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
STU_RS14915	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
STU_RS14915	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
STU_RS14925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
STU_RS14930	COG1956	GAF domain-containing protein
STU_RS14935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
STU_RS14950	COG0335	large ribosomal subunit rRNA binding
STU_RS14955	COG0038	chloride channel
STU_RS14965	COG0038	chloride channel
STU_RS15040	COG0469	pyruvate kinase activity
STU_RS15065	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
STU_RS15090	COG0167	dihydroorotate dehydrogenase activity
STU_RS15100	COG0776	regulation of translation
STU_RS15110	COG2755	lipolytic protein G-D-S-L family
STU_RS15115	COG1307	EDD domain protein, DegV family
STU_RS15120	COG0497	DNA recombination
STU_RS15125	COG1438	arginine binding
STU_RS15130	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
STU_RS15155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STU_RS15165	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
STU_RS15175	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
STU_RS15175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
STU_RS15180	COG0300	oxidoreductase activity
STU_RS15195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
STU_RS15200	COG0772	Belongs to the SEDS family
STU_RS15225	COG0647	UMP catabolic process
STU_RS15235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
STU_RS15255	COG1088	dTDP-glucose 4,6-dehydratase activity
STU_RS15265	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
STU_RS15270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
STU_RS15290	COG2384	SAM-dependent methyltransferase
STU_RS15315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STU_RS15320	COG3442	glutamine amidotransferase
STU_RS15325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
STU_RS15325	COG0392	lysyltransferase activity
STU_RS15340	COG0488	(ABC) transporter
STU_RS15350	COG0513	Belongs to the DEAD box helicase family
STU_RS15380	COG0372	Belongs to the citrate synthase family
STU_RS15385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
STU_RS15390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
STU_RS15395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STU_RS15400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STU_RS15450	COG0488	(ABC) transporter
STU_RS15480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
STU_RS15480	COG1328	CTP reductase activity
STU_RS15515	COG1196	nuclear chromosome segregation
STU_RS15530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STU_RS15560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STU_RS15565	COG0322	excinuclease ABC activity
STU_RS15570	COG1011	Hydrolase
STU_RS15575	COG1268	BioY protein
STU_RS15585	COG1125	glycine betaine transport
STU_RS15585	COG0517	IMP dehydrogenase activity
STU_RS15600	COG2986	histidine ammonia-lyase
STU_RS15610	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
STU_RS15615	COG1760	l-serine dehydratase
STU_RS15620	COG1760	l-serine dehydratase
STU_RS15645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
STU_RS15655	COG2197	response regulator
STU_RS15660	COG4585	Histidine kinase
STU_RS15670	COG1131	(ABC) transporter
STU_RS15685	COG0385	Bile acid
STU_RS15700	COG0577	efflux transmembrane transporter activity
STU_RS15705	COG1136	(ABC) transporter
STU_RS15710	COG5002	protein histidine kinase activity
STU_RS15710	COG0784	Response regulator, receiver
STU_RS15710	COG2198	Histidine kinase
STU_RS15715	COG0745	RESPONSE REGULATOR receiver
STU_RS15725	COG2233	PERMEase
STU_RS15730	COG2233	PERMEase
STU_RS15735	COG0534	Mate efflux family protein
STU_RS15740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STU_RS15740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STU_RS15745	COG2801	Transposase and inactivated derivatives
STU_RS15760	COG1482	cell wall glycoprotein biosynthetic process
STU_RS15765	COG1482	cell wall glycoprotein biosynthetic process
STU_RS15775	COG0531	amino acid
STU_RS15790	COG1959	2 iron, 2 sulfur cluster binding
STU_RS15800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STU_RS15800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STU_RS15805	COG0778	Nitroreductase
STU_RS15815	COG0656	L-ascorbic acid biosynthetic process
STU_RS15820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STU_RS15835	COG4868	Belongs to the UPF0371 family
STU_RS15865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STU_RS15885	COG1280	lysine exporter protein (LysE YggA)
STU_RS15895	COG1442	glycosyl transferase family 8
STU_RS15895	COG1216	Glycosyl transferase, family 2
STU_RS15910	COG0419	ATPase involved in DNA repair
STU_RS15915	COG0420	3'-5' exonuclease activity
STU_RS15920	COG3250	beta-galactosidase activity
STU_RS15925	COG2190	(PTS) system
STU_RS15925	COG2211	Major facilitator Superfamily
STU_RS15930	COG2017	converts alpha-aldose to the beta-anomer
STU_RS15935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STU_RS15940	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
STU_RS15950	COG1609	Transcriptional regulator
STU_RS15970	COG0488	(ABC) transporter
STU_RS15985	COG2918	glutathione biosynthetic process
STU_RS15985	COG1181	Belongs to the D-alanine--D-alanine ligase family
STU_RS16030	COG2197	response regulator
STU_RS16035	COG4585	Histidine kinase
STU_RS16045	COG2815	serine threonine protein kinase
STU_RS16045	COG0515	serine threonine protein kinase
STU_RS16055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STU_RS16055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
STU_RS16065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
STU_RS16080	COG0552	protein localization to endoplasmic reticulum
STU_RS16085	COG0561	phosphatase activity
STU_RS16090	COG0561	phosphatase activity
STU_RS16095	COG1725	Transcriptional regulator
STU_RS16100	COG1131	(ABC) transporter
STU_RS16110	COG4608	Belongs to the ABC transporter superfamily
STU_RS16115	COG0444	Belongs to the ABC transporter superfamily
STU_RS16120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STU_RS16125	COG0601	transmembrane transport
STU_RS16130	COG4166	transmembrane transport
STU_RS16140	COG4166	transmembrane transport
STU_RS16145	COG4608	Belongs to the ABC transporter superfamily
STU_RS16155	COG2223	nitrite transmembrane transporter activity
STU_RS16160	COG2801	Transposase and inactivated derivatives
STU_RS16175	COG0280	phosphate acetyltransferase
STU_RS16180	COG0564	pseudouridine synthase activity
STU_RS16190	COG2357	RelA SpoT domain protein
STU_RS16205	COG1104	cysteine desulfurase activity
STU_RS16220	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
STU_RS16225	COG2003	Belongs to the UPF0758 family
STU_RS16250	COG1215	transferase activity, transferring glycosyl groups
STU_RS16260	COG1216	Glycosyl transferase, family 2
STU_RS16260	COG1442	glycosyl transferase family 8
STU_RS16280	COG1091	dTDP-4-dehydrorhamnose reductase activity
STU_RS16290	COG0463	Glycosyl transferase, family 2
STU_RS16300	COG2151	metal-sulfur cluster biosynthetic enzyme
STU_RS16305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STU_RS16310	COG0358	DNA primase activity
STU_RS16320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STU_RS16325	COG0436	Aminotransferase
STU_RS16330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STU_RS16335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STU_RS16340	COG1051	belongs to the nudix hydrolase family
STU_RS16365	COG0765	amino acid transport
STU_RS16370	COG1126	abc transporter atp-binding protein
STU_RS16385	COG1187	pseudouridine synthase activity
STU_RS16420	COG1132	(ABC) transporter
STU_RS16455	COG0560	Phosphoserine phosphatase
STU_RS16465	COG0187	DNA topoisomerase II activity
STU_RS16475	COG1346	cytolysis
STU_RS16480	COG1380	Effector of murein hydrolase LrgA
STU_RS16490	COG1393	Belongs to the ArsC family
STU_RS16500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
STU_RS16510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
STU_RS16515	COG1940	carbohydrate kinase activity
STU_RS16540	COG1177	transmembrane transport
STU_RS16545	COG1176	ABC-type spermidine putrescine transport system, permease component I
STU_RS16550	COG3842	ATPase activity
STU_RS16585	COG0531	amino acid
STU_RS16590	COG0285	dihydrofolate synthase activity
STU_RS16595	COG1837	Belongs to the UPF0109 family
STU_RS16605	COG0500	methyltransferase
STU_RS16605	COG3615	Tellurite resistance protein tehB
STU_RS16615	COG0708	Exodeoxyribonuclease III
STU_RS16630	COG1597	lipid kinase activity
STU_RS16640	COG4708	membrane
STU_RS16650	COG0024	Methionine aminopeptidase
STU_RS16655	COG4109	DRTGG domain
STU_RS16665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
STU_RS16670	COG2333	competence protein COMEC
STU_RS16670	COG0658	competence protein
STU_RS16675	COG1555	photosystem II stabilization
STU_RS16675	COG1596	polysaccharide export
STU_RS16680	COG0204	Acyl-transferase
STU_RS16690	COG0726	polysaccharide deacetylase
STU_RS16695	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
STU_RS16705	COG0513	Belongs to the DEAD box helicase family
STU_RS16725	COG1396	sequence-specific DNA binding
STU_RS16730	COG2211	Major facilitator Superfamily
STU_RS16745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STU_RS16760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STU_RS16765	COG1126	abc transporter atp-binding protein
STU_RS16770	COG0765	amino acid transport
STU_RS16775	COG0765	amino acid transport
STU_RS16780	COG1181	Belongs to the D-alanine--D-alanine ligase family
STU_RS16790	COG2217	Heavy metal translocating P-type atpase
STU_RS16800	COG0159	tryptophan synthase activity
STU_RS16805	COG0133	tryptophan synthase activity
STU_RS16810	COG0135	phosphoribosylanthranilate isomerase activity
STU_RS16815	COG0134	indole-3-glycerol-phosphate synthase activity
STU_RS16820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
STU_RS16825	COG0512	Glutamine amidotransferase of anthranilate synthase
STU_RS16830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STU_RS16835	COG1605	Chorismate mutase
STU_RS16835	COG0287	Prephenate dehydrogenase
STU_RS16845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STU_RS16865	COG0789	Transcriptional regulator
STU_RS16870	COG2176	DNA-directed DNA polymerase activity
STU_RS16880	COG2151	metal-sulfur cluster biosynthetic enzyme
STU_RS16890	COG2081	HI0933 family
STU_RS16915	COG1131	(ABC) transporter
STU_RS16920	COG0537	adenosine 5'-monophosphoramidase activity
STU_RS16945	COG1323	Belongs to the UPF0348 family
STU_RS16950	COG2226	methyltransferase
STU_RS16955	COG0799	negative regulation of ribosome biogenesis
STU_RS16960	COG1713	HD superfamily hydrolase involved in NAD metabolism
STU_RS16965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
STU_RS16970	COG1534	Rna-binding protein
STU_RS16975	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STU_RS16980	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
STU_RS17030	COG1335	isochorismatase
STU_RS17040	COG0436	Aminotransferase
STU_RS17045	COG0589	response to stress
STU_RS17060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STU_RS17065	COG1253	flavin adenine dinucleotide binding
STU_RS17070	COG1119	ATPase activity
STU_RS17075	COG0025	NhaP-type Na H and K H
STU_RS17085	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
STU_RS17090	COG1242	4 iron, 4 sulfur cluster binding
STU_RS17095	COG3480	Lon protease (S16) C-terminal proteolytic domain
STU_RS17100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
STU_RS17105	COG0742	ribosomal rna small subunit methyltransferase
STU_RS17110	COG0492	ferredoxin-NADP+ reductase activity
STU_RS17120	COG1126	abc transporter atp-binding protein
STU_RS17130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STU_RS17140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STU_RS17145	COG1882	Formate acetyltransferase
STU_RS17190	COG0390	transport system, permease component
STU_RS17195	COG4619	ABC transporter
STU_RS17205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
STU_RS17220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STU_RS17225	COG2936	dipeptidyl-peptidase activity
STU_RS17250	COG2801	Transposase and inactivated derivatives
STU_RS17295	COG2274	protein secretion by the type I secretion system
STU_RS17300	COG1132	(ABC) transporter
STU_RS17305	COG1132	(ABC) transporter
STU_RS17320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
STU_RS17325	COG4470	Protein conserved in bacteria
STU_RS17330	COG0737	Belongs to the 5'-nucleotidase family
STU_RS17340	COG0513	Belongs to the DEAD box helicase family
STU_RS17345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STU_RS17350	COG0768	penicillin binding
STU_RS17360	COG0275	rRNA processing
STU_RS17375	COG3152	Membrane
STU_RS17410	COG1074	ATP-dependent DNA helicase activity
STU_RS17415	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
STU_RS17445	COG0561	phosphatase activity
STU_RS17450	COG0252	asparaginase activity
STU_RS17455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STU_RS17460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
STU_RS17470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STU_RS17475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STU_RS17480	COG0653	protein targeting
STU_RS17490	COG1482	cell wall glycoprotein biosynthetic process
STU_RS17495	COG1940	carbohydrate kinase activity
STU_RS17500	COG2190	(PTS) system
STU_RS17500	COG1263	PTS System
STU_RS17500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STU_RS17505	COG1621	beta-fructofuranosidase activity
STU_RS17525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
STU_RS17530	COG2131	deaminase
STU_RS17535	COG0006	proline dipeptidase activity
STU_RS17630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STU_RS17630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STU_RS17635	COG1193	negative regulation of DNA recombination
STU_RS17650	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
STU_RS17655	COG0681	Belongs to the peptidase S26 family
STU_RS17660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
STU_RS17670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
STU_RS17680	COG0456	acetyltransferase
STU_RS17685	COG1214	PFAM Peptidase M22, glycoprotease
STU_RS17705	COG0174	glutamine synthetase
STU_RS17710	COG0789	Transcriptional regulator
STU_RS17725	COG0126	phosphoglycerate kinase activity
STU_RS17745	COG2801	Transposase and inactivated derivatives
STU_RS17775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
STU_RS17810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
STU_RS17820	COG0084	hydrolase, TatD family'
STU_RS17825	COG1832	CoA-binding protein
STU_RS17830	COG3118	belongs to the thioredoxin family
STU_RS17870	COG0343	queuine tRNA-ribosyltransferase activity
STU_RS17890	COG0706	membrane insertase activity
STU_RS17955	COG0756	dUTP diphosphatase activity
STU_RS17990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STU_RS17995	COG2801	Transposase and inactivated derivatives
STU_RS18005	COG0457	Tetratricopeptide repeat
STU_RS18005	COG0705	Rhomboid family
STU_RS18010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STU_RS18030	COG2226	methyltransferase
STU_RS18055	COG0425	Belongs to the sulfur carrier protein TusA family
STU_RS18060	COG2391	methyltransferase activity
STU_RS18065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STU_RS18070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STU_RS18080	COG1363	Peptidase, m42
STU_RS18085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
STU_RS18090	COG1266	CAAX protease self-immunity
STU_RS18145	COG1459	type II secretion system
STU_RS18150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STU_RS18170	COG4499	WXG100 protein secretion system (Wss), protein YukC
STU_RS18170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STU_RS18185	COG0440	acetolactate synthase activity
STU_RS18190	COG0028	Belongs to the TPP enzyme family
STU_RS18195	COG0129	dihydroxy-acid dehydratase activity
STU_RS18200	COG1461	Dihydroxyacetone kinase
STU_RS18210	COG0534	Mate efflux family protein
STU_RS18235	COG1454	alcohol dehydrogenase
STU_RS18235	COG1012	belongs to the aldehyde dehydrogenase family
STU_RS18245	COG1012	belongs to the aldehyde dehydrogenase family
STU_RS18245	COG1454	alcohol dehydrogenase
STU_RS18250	COG3590	peptidase
STU_RS18255	COG0366	Alpha amylase catalytic
STU_RS18260	COG0366	Alpha amylase catalytic
STU_RS18270	COG1609	Transcriptional regulator
STU_RS18275	COG2188	Transcriptional regulator
STU_RS18280	COG4475	Protein of unknown function (DUF436)
STU_RS18305	COG0191	fructose-bisphosphate aldolase activity
STU_RS18375	COG0201	protein transport
STU_RS18480	COG0051	transcription antitermination factor activity, RNA binding
STU_RS18520	COG3328	transposase activity
STU_RS18530	COG0515	serine threonine protein kinase
STU_RS18535	COG1132	(ABC) transporter
STU_RS18540	COG1396	sequence-specific DNA binding
STU_RS18550	COG1132	(ABC) transporter
STU_RS18580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
STU_RS18610	COG1328	CTP reductase activity
STU_RS18620	COG0602	queuosine metabolic process
STU_RS18625	COG3022	response to hydroperoxide
STU_RS18630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STU_RS18635	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
STU_RS18650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
STU_RS18655	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
STU_RS18665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STU_RS18680	COG1597	lipid kinase activity
STU_RS18695	COG2261	transglycosylase associated protein
STU_RS18720	COG3237	CsbD-like
STU_RS18755	COG3759	membrane
STU_RS18770	COG0305	Participates in initiation and elongation during chromosome replication
STU_RS18800	COG0741	lytic transglycosylase activity
STU_RS18805	COG3584	3D domain protein
STU_RS18805	COG1388	LysM domain
STU_RS18810	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
STU_RS18825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
STU_RS18835	COG0612	Peptidase, M16
STU_RS18850	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
STU_RS18875	COG0488	(ABC) transporter
STU_RS18910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STU_RS18915	COG1475	DNA binding
STU_RS18955	COG0110	maltose O-acetyltransferase activity
STU_RS18965	COG1215	transferase activity, transferring glycosyl groups
STU_RS18975	COG4166	transmembrane transport
STU_RS18980	COG4166	transmembrane transport