locus-tag	class	description
MNA02_RS00010	COG0592	DNA-directed DNA polymerase activity
MNA02_RS00020	COG0012	GTP binding
MNA02_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MNA02_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MNA02_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MNA02_RS00085	COG2801	Transposase and inactivated derivatives
MNA02_RS00205	COG3942	CHAP domain
MNA02_RS00220	COG0436	Aminotransferase
MNA02_RS00235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNA02_RS00245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNA02_RS00260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MNA02_RS00280	COG2801	Transposase and inactivated derivatives
MNA02_RS00285	COG1388	LysM domain
MNA02_RS00285	COG3942	CHAP domain
MNA02_RS00290	COG0151	Belongs to the GarS family
MNA02_RS00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MNA02_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MNA02_RS00330	COG4550	Control of competence regulator ComK, YlbF/YmcA
MNA02_RS00370	COG2818	Glycosylase
MNA02_RS00385	COG1393	Belongs to the ArsC family
MNA02_RS00475	COG2309	aminopeptidase activity
MNA02_RS00495	COG2801	Transposase and inactivated derivatives
MNA02_RS00515	COG1619	proteins homologs of microcin C7 resistance protein MccF
MNA02_RS00540	COG4463	regulation of RNA biosynthetic process
MNA02_RS00545	COG0542	response to heat
MNA02_RS00555	COG1686	Belongs to the peptidase S11 family
MNA02_RS00570	COG1045	serine acetyltransferase
MNA02_RS00580	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MNA02_RS00595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNA02_RS00620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MNA02_RS00680	COG1705	Flagellar rod assembly protein muramidase FlgJ
MNA02_RS00680	COG3942	CHAP domain
MNA02_RS00695	COG3830	Belongs to the UPF0237 family
MNA02_RS00710	COG1876	peptidase activity
MNA02_RS00745	COG0351	phosphomethylpyrimidine kinase
MNA02_RS00750	COG4720	Psort location CytoplasmicMembrane, score
MNA02_RS00790	COG1473	amidohydrolase
MNA02_RS00795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MNA02_RS00810	COG0668	transmembrane transport
MNA02_RS00825	COG0504	CTP synthase activity
MNA02_RS00835	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MNA02_RS00845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MNA02_RS00850	COG0737	Belongs to the 5'-nucleotidase family
MNA02_RS00885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MNA02_RS00915	COG1126	abc transporter atp-binding protein
MNA02_RS00920	COG0765	amino acid transport
MNA02_RS00935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MNA02_RS00945	COG0719	Fe-S assembly protein
MNA02_RS00950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MNA02_RS00960	COG0719	Fe-S assembly protein
MNA02_RS00965	COG4166	transmembrane transport
MNA02_RS00970	COG0601	transmembrane transport
MNA02_RS00990	COG0444	Belongs to the ABC transporter superfamily
MNA02_RS00995	COG0444	Belongs to the ABC transporter superfamily
MNA02_RS01015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MNA02_RS01030	COG1121	(ABC) transporter
MNA02_RS01035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MNA02_RS01045	COG1263	PTS System
MNA02_RS01045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNA02_RS01045	COG2190	(PTS) system
MNA02_RS01050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNA02_RS01050	COG2190	(PTS) system
MNA02_RS01050	COG1263	PTS System
MNA02_RS01055	COG1263	PTS System
MNA02_RS01055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNA02_RS01055	COG2190	(PTS) system
MNA02_RS01085	COG4589	Belongs to the CDS family
MNA02_RS01100	COG4120	Belongs to the binding-protein-dependent transport system permease family
MNA02_RS01105	COG1116	anion transmembrane transporter activity
MNA02_RS01105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MNA02_RS01150	COG0564	pseudouridine synthase activity
MNA02_RS01155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MNA02_RS01180	COG1349	DNA-binding transcription factor activity
MNA02_RS01205	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MNA02_RS01220	COG3579	cysteine-type endopeptidase activity
MNA02_RS01225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MNA02_RS01245	COG0116	Belongs to the methyltransferase superfamily
MNA02_RS01255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MNA02_RS01275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MNA02_RS01300	COG1254	Belongs to the acylphosphatase family
MNA02_RS01305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNA02_RS01350	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MNA02_RS01370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MNA02_RS01375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MNA02_RS01380	COG1187	pseudouridine synthase activity
MNA02_RS01390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MNA02_RS01395	COG0569	domain protein
MNA02_RS01405	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MNA02_RS01410	COG0671	phosphoesterase, PA-phosphatase related
MNA02_RS01430	COG2274	protein secretion by the type I secretion system
MNA02_RS01435	COG2274	protein secretion by the type I secretion system
MNA02_RS01440	COG2274	protein secretion by the type I secretion system
MNA02_RS01490	COG0829	nickel cation binding
MNA02_RS01495	COG0310	cobalt ion transport
MNA02_RS01505	COG1122	ATPase activity
MNA02_RS01510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNA02_RS01515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MNA02_RS01535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNA02_RS01540	COG1464	Belongs to the NlpA lipoprotein family
MNA02_RS01550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MNA02_RS01575	COG1122	ATPase activity
MNA02_RS01585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MNA02_RS01595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MNA02_RS01610	COG0745	RESPONSE REGULATOR receiver
MNA02_RS01615	COG5002	protein histidine kinase activity
MNA02_RS01630	COG1484	DNA-dependent DNA replication
MNA02_RS01645	COG2801	Transposase and inactivated derivatives
MNA02_RS01675	COG3716	PTS system mannose fructose sorbose family IID component
MNA02_RS01680	COG3715	PTS system
MNA02_RS01690	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MNA02_RS01695	COG0561	phosphatase activity
MNA02_RS01700	COG2252	PERMEase
MNA02_RS01705	COG0802	atpase or kinase
MNA02_RS01710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MNA02_RS01715	COG1316	TRANSCRIPTIONal
MNA02_RS01725	COG0195	Participates in both transcription termination and antitermination
MNA02_RS01730	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MNA02_RS01750	COG1611	Belongs to the LOG family
MNA02_RS01770	COG2244	polysaccharide biosynthetic process
MNA02_RS01775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MNA02_RS01780	COG0626	cystathionine gamma-synthase activity
MNA02_RS01785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MNA02_RS01815	COG4471	UPF0298 protein
MNA02_RS01825	COG0559	Belongs to the binding-protein-dependent transport system permease family
MNA02_RS01845	COG0517	IMP dehydrogenase activity
MNA02_RS01860	COG1739	Uncharacterized protein family UPF0029
MNA02_RS01865	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MNA02_RS01870	COG1040	competence protein
MNA02_RS01960	COG0527	aspartate kinase activity
MNA02_RS01965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MNA02_RS01970	COG1024	Enoyl-CoA hydratase
MNA02_RS01975	COG1846	Transcriptional regulator
MNA02_RS01995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MNA02_RS02000	COG1028	Short-chain dehydrogenase reductase Sdr
MNA02_RS02005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MNA02_RS02020	COG0439	Biotin carboxylase
MNA02_RS02055	COG1349	DNA-binding transcription factor activity
MNA02_RS02060	COG1105	Belongs to the carbohydrate kinase PfkB family
MNA02_RS02070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MNA02_RS02075	COG0285	dihydrofolate synthase activity
MNA02_RS02085	COG1104	cysteine desulfurase activity
MNA02_RS02150	COG0488	(ABC) transporter
MNA02_RS02170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MNA02_RS02175	COG0242	peptide deformylase activity
MNA02_RS02235	COG1702	phosphate starvation-inducible protein PhoH
MNA02_RS02255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNA02_RS02255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNA02_RS02280	COG4122	O-methyltransferase activity
MNA02_RS02285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MNA02_RS02315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MNA02_RS02320	COG0436	Aminotransferase
MNA02_RS02335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MNA02_RS02340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MNA02_RS02345	COG0726	polysaccharide deacetylase
MNA02_RS02360	COG2962	Rard protein
MNA02_RS02400	COG0356	it plays a direct role in the translocation of protons across the membrane
MNA02_RS02435	COG0772	Belongs to the SEDS family
MNA02_RS02455	COG0470	DNA polymerase III
MNA02_RS02460	COG1774	PSP1 C-terminal conserved region
MNA02_RS02465	COG4467	Involved in initiation control of chromosome replication
MNA02_RS02475	COG0004	ammonium transporteR
MNA02_RS02480	COG0347	Belongs to the P(II) protein family
MNA02_RS02485	COG1388	LysM domain
MNA02_RS02485	COG1705	Flagellar rod assembly protein muramidase FlgJ
MNA02_RS02545	COG1113	amino acid transport
MNA02_RS02555	COG1263	PTS System
MNA02_RS02555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNA02_RS02555	COG2190	(PTS) system
MNA02_RS02570	COG2801	Transposase and inactivated derivatives
MNA02_RS02600	COG0583	DNA-binding transcription factor activity
MNA02_RS02610	COG0564	pseudouridine synthase activity
MNA02_RS02630	COG0505	Belongs to the CarA family
MNA02_RS02665	COG0577	efflux transmembrane transporter activity
MNA02_RS02670	COG0577	efflux transmembrane transporter activity
MNA02_RS02700	COG0577	efflux transmembrane transporter activity
MNA02_RS02750	COG3279	Response regulator of the LytR AlgR family
MNA02_RS02760	COG1131	(ABC) transporter
MNA02_RS02795	COG1187	pseudouridine synthase activity
MNA02_RS02800	COG1473	amidohydrolase
MNA02_RS02805	COG0686	Belongs to the AlaDH PNT family
MNA02_RS02810	COG0686	Belongs to the AlaDH PNT family
MNA02_RS02815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MNA02_RS02880	COG0438	transferase activity, transferring glycosyl groups
MNA02_RS02910	COG1272	protein, Hemolysin III
MNA02_RS02925	COG3425	synthase
MNA02_RS02935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MNA02_RS02955	COG0833	amino acid
MNA02_RS02960	COG2040	homocysteine
MNA02_RS02980	COG0187	DNA topoisomerase II activity
MNA02_RS02990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MNA02_RS03010	COG0539	negative regulation of cytoplasmic translation
MNA02_RS03035	COG0673	inositol 2-dehydrogenase activity
MNA02_RS03050	COG0494	nUDIX hydrolase
MNA02_RS03055	COG0542	response to heat
MNA02_RS03060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MNA02_RS03065	COG4703	Protein of unknown function (DUF1797)
MNA02_RS03070	COG0765	amino acid transport
MNA02_RS03120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MNA02_RS03125	COG0768	penicillin binding
MNA02_RS03130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MNA02_RS03140	COG3711	transcriptional antiterminator
MNA02_RS03150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MNA02_RS03155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MNA02_RS03160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MNA02_RS03165	COG0237	dephospho-CoA kinase activity
MNA02_RS03180	COG0557	exoribonuclease II activity
MNA02_RS03195	COG1185	polyribonucleotide nucleotidyltransferase activity
MNA02_RS03200	COG0006	proline dipeptidase activity
MNA02_RS03205	COG1609	Transcriptional regulator
MNA02_RS03235	COG1368	sulfuric ester hydrolase activity
MNA02_RS03240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MNA02_RS03265	COG0287	Prephenate dehydrogenase
MNA02_RS03290	COG0077	Prephenate dehydratase
MNA02_RS03350	COG2963	transposase activity
MNA02_RS03360	COG2801	Transposase and inactivated derivatives
MNA02_RS03415	COG1518	maintenance of DNA repeat elements
MNA02_RS03420	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNA02_RS03430	COG3689	TIGRFAM TIGR03943 family protein
MNA02_RS03435	COG0701	Predicted permease
MNA02_RS03440	COG2183	response to ionizing radiation
MNA02_RS03485	COG0826	peptidase U32
MNA02_RS03495	COG1268	BioY protein
MNA02_RS03505	COG4443	Transcriptional Coactivator p15 (PC4)
MNA02_RS03515	COG1914	H( )-stimulated, divalent metal cation uptake system
MNA02_RS03525	COG0494	nUDIX hydrolase
MNA02_RS03535	COG3328	transposase activity
MNA02_RS03545	COG1705	Flagellar rod assembly protein muramidase FlgJ
MNA02_RS03545	COG1388	LysM domain
MNA02_RS03560	COG0406	alpha-ribazole phosphatase activity
MNA02_RS03565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MNA02_RS03600	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MNA02_RS03650	COG1704	LemA family
MNA02_RS03680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MNA02_RS03690	COG0783	Belongs to the Dps family
MNA02_RS03695	COG0735	belongs to the Fur family
MNA02_RS03700	COG4483	Protein conserved in bacteria
MNA02_RS03705	COG1940	carbohydrate kinase activity
MNA02_RS03710	COG1217	gtp-binding protein TYPA
MNA02_RS03735	COG0849	cell division
MNA02_RS03745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MNA02_RS03765	COG3599	regulation of cell shape
MNA02_RS03800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MNA02_RS03805	COG0625	glutathione transferase activity
MNA02_RS03815	COG1435	thymidine kinase activity
MNA02_RS03825	COG2890	protein-(glutamine-N5) methyltransferase activity
MNA02_RS03855	COG1132	(ABC) transporter
MNA02_RS03870	COG1696	Membrane protein involved in D-alanine export
MNA02_RS03880	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MNA02_RS03885	COG2801	Transposase and inactivated derivatives
MNA02_RS03890	COG2801	Transposase and inactivated derivatives
MNA02_RS03910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MNA02_RS03915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MNA02_RS03975	COG1396	sequence-specific DNA binding
MNA02_RS03980	COG0582	viral genome integration into host DNA
MNA02_RS04000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MNA02_RS04005	COG4684	Psort location CytoplasmicMembrane, score
MNA02_RS04010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MNA02_RS04035	COG5002	protein histidine kinase activity
MNA02_RS04040	COG5002	protein histidine kinase activity
MNA02_RS04050	COG2801	Transposase and inactivated derivatives
MNA02_RS04070	COG0038	chloride channel
MNA02_RS04090	COG2801	Transposase and inactivated derivatives
MNA02_RS04110	COG2813	Specifically methylates the guanine in position
MNA02_RS04130	COG0295	cytidine deaminase activity
MNA02_RS04135	COG1744	ABC transporter substrate-binding protein PnrA-like
MNA02_RS04140	COG3845	ABC transporter
MNA02_RS04145	COG4603	Belongs to the binding-protein-dependent transport system permease family
MNA02_RS04150	COG1079	Belongs to the binding-protein-dependent transport system permease family
MNA02_RS04160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MNA02_RS04160	COG1199	ATP-dependent helicase activity
MNA02_RS04170	COG0436	Aminotransferase
MNA02_RS04200	COG0251	oxidation-reduction process
MNA02_RS04210	COG0720	synthase
MNA02_RS04255	COG1278	Cold shock
MNA02_RS04265	COG2801	Transposase and inactivated derivatives
MNA02_RS04275	COG3328	transposase activity
MNA02_RS04280	COG2217	Heavy metal translocating P-type atpase
MNA02_RS04285	COG3328	transposase activity
MNA02_RS04295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MNA02_RS04300	COG0626	cystathionine gamma-synthase activity
MNA02_RS04305	COG1045	serine acetyltransferase
MNA02_RS04310	COG3328	transposase activity
MNA02_RS04325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MNA02_RS04330	COG4975	Glucose uptake
MNA02_RS04350	COG3443	Belongs to the bacterial solute-binding protein 9 family
MNA02_RS04350	COG0803	Belongs to the bacterial solute-binding protein 9 family
MNA02_RS04370	COG3942	CHAP domain
MNA02_RS04370	COG1705	Flagellar rod assembly protein muramidase FlgJ
MNA02_RS04385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MNA02_RS04390	COG2824	Alkylphosphonate utilization operon protein PhnA
MNA02_RS04395	COG0765	amino acid transport
MNA02_RS04400	COG1126	abc transporter atp-binding protein
MNA02_RS04405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNA02_RS04425	COG1064	alcohol dehydrogenase
MNA02_RS04440	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MNA02_RS04445	COG0519	Catalyzes the synthesis of GMP from XMP
MNA02_RS04445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MNA02_RS04450	COG2188	Transcriptional regulator
MNA02_RS04460	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MNA02_RS04470	COG1827	regulation of RNA biosynthetic process
MNA02_RS04480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MNA02_RS04490	COG1940	carbohydrate kinase activity
MNA02_RS04495	COG0758	DNA mediated transformation
MNA02_RS04500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MNA02_RS04550	COG1396	sequence-specific DNA binding
MNA02_RS04560	COG3328	transposase activity
MNA02_RS04565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MNA02_RS04570	COG0010	Belongs to the arginase family
MNA02_RS04580	COG0028	Belongs to the TPP enzyme family
MNA02_RS04585	COG3527	Alpha-acetolactate decarboxylase
MNA02_RS04620	COG1230	cation diffusion facilitator family transporter
MNA02_RS04630	COG1063	alcohol dehydrogenase
MNA02_RS04655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MNA02_RS04675	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MNA02_RS04685	COG0047	phosphoribosylformylglycinamidine synthase activity
MNA02_RS04695	COG0167	dihydroorotate dehydrogenase activity
MNA02_RS04700	COG1468	defense response to virus
MNA02_RS04700	COG1518	maintenance of DNA repeat elements
MNA02_RS04705	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNA02_RS04725	COG1337	RAMP superfamily
MNA02_RS04730	COG1567	CRISPR-associated RAMP protein, Csm4 family
MNA02_RS04745	COG0284	orotidine-5'-phosphate decarboxylase activity
MNA02_RS04760	COG3104	oligopeptide transport
MNA02_RS04775	COG0737	Belongs to the 5'-nucleotidase family
MNA02_RS04800	COG1115	amino acid carrier protein
MNA02_RS04810	COG2873	o-acetylhomoserine
MNA02_RS04840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MNA02_RS04845	COG0196	riboflavin kinase activity
MNA02_RS04850	COG1393	Belongs to the ArsC family
MNA02_RS04860	COG0483	inositol monophosphate 1-phosphatase activity
MNA02_RS04865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MNA02_RS04865	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
MNA02_RS04875	COG0573	inorganic phosphate transmembrane transporter activity
MNA02_RS04880	COG0581	inorganic phosphate transmembrane transporter activity
MNA02_RS04895	COG0704	Plays a role in the regulation of phosphate uptake
MNA02_RS04910	COG0095	Lipoate-protein ligase
MNA02_RS04925	COG0058	SHG alpha-glucan phosphorylase activity
MNA02_RS04930	COG1640	4-alpha-glucanotransferase
MNA02_RS04945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MNA02_RS04950	COG0805	protein transport
MNA02_RS04955	COG0672	)-iron permease
MNA02_RS04960	COG2837	iron assimilation
MNA02_RS04965	COG2822	iron ion transport
MNA02_RS04970	COG4607	ABC-type enterochelin transport system periplasmic component
MNA02_RS04975	COG4604	ABC transporter, ATP-binding protein
MNA02_RS04980	COG4605	iron ion homeostasis
MNA02_RS04985	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNA02_RS04995	COG1523	belongs to the glycosyl hydrolase 13 family
MNA02_RS05005	COG1523	belongs to the glycosyl hydrolase 13 family
MNA02_RS05030	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNA02_RS05035	COG0022	dehydrogenase e1 component
MNA02_RS05035	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNA02_RS05040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MNA02_RS05060	COG1518	maintenance of DNA repeat elements
MNA02_RS05075	COG1857	crispr-associated protein
MNA02_RS05110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MNA02_RS05120	COG4667	esterase of the alpha-beta hydrolase superfamily
MNA02_RS05150	COG0628	permease
MNA02_RS05175	COG0562	UDP-galactopyranose mutase
MNA02_RS05185	COG2244	polysaccharide biosynthetic process
MNA02_RS05190	COG1442	glycosyl transferase family 8
MNA02_RS05190	COG1216	Glycosyl transferase, family 2
MNA02_RS05205	COG1442	glycosyl transferase family 8
MNA02_RS05205	COG1216	Glycosyl transferase, family 2
MNA02_RS05250	COG1316	TRANSCRIPTIONal
MNA02_RS05255	COG3328	transposase activity
MNA02_RS05275	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MNA02_RS05285	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MNA02_RS05305	COG1573	uracil-dna glycosylase
MNA02_RS05365	COG0681	Belongs to the peptidase S26 family
MNA02_RS05375	COG0628	permease
MNA02_RS05380	COG1051	belongs to the nudix hydrolase family
MNA02_RS05385	COG2177	Part of the ABC transporter FtsEX involved in
MNA02_RS05390	COG2884	Cell division ATP-binding protein ftsE
MNA02_RS05395	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MNA02_RS05400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MNA02_RS05435	COG2348	transferase activity, transferring amino-acyl groups
MNA02_RS05445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MNA02_RS05450	COG5002	protein histidine kinase activity
MNA02_RS05455	COG0745	RESPONSE REGULATOR receiver
MNA02_RS05460	COG1126	abc transporter atp-binding protein
MNA02_RS05465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNA02_RS05470	COG0765	amino acid transport
MNA02_RS05475	COG0765	amino acid transport
MNA02_RS05500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MNA02_RS05510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MNA02_RS05515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MNA02_RS05515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MNA02_RS05525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MNA02_RS05530	COG1956	GAF domain-containing protein
MNA02_RS05535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MNA02_RS05550	COG0335	large ribosomal subunit rRNA binding
MNA02_RS05555	COG0038	chloride channel
MNA02_RS05565	COG0038	chloride channel
MNA02_RS05570	COG0716	FMN binding
MNA02_RS05645	COG0469	pyruvate kinase activity
MNA02_RS05695	COG0167	dihydroorotate dehydrogenase activity
MNA02_RS05705	COG0776	regulation of translation
MNA02_RS05715	COG2755	lipolytic protein G-D-S-L family
MNA02_RS05720	COG1307	EDD domain protein, DegV family
MNA02_RS05725	COG0497	DNA recombination
MNA02_RS05730	COG1438	arginine binding
MNA02_RS05735	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MNA02_RS05760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MNA02_RS05780	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MNA02_RS05780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MNA02_RS05785	COG0300	oxidoreductase activity
MNA02_RS05800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MNA02_RS05810	COG0772	Belongs to the SEDS family
MNA02_RS05825	COG0107	imidazoleglycerol-phosphate synthase activity
MNA02_RS05835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MNA02_RS05845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MNA02_RS05900	COG0647	UMP catabolic process
MNA02_RS05910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MNA02_RS05940	COG1088	dTDP-glucose 4,6-dehydratase activity
MNA02_RS05950	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MNA02_RS05955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MNA02_RS05970	COG2384	SAM-dependent methyltransferase
MNA02_RS05995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MNA02_RS06000	COG3442	glutamine amidotransferase
MNA02_RS06020	COG0488	(ABC) transporter
MNA02_RS06030	COG0513	Belongs to the DEAD box helicase family
MNA02_RS06065	COG0372	Belongs to the citrate synthase family
MNA02_RS06070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MNA02_RS06075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MNA02_RS06080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNA02_RS06085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNA02_RS06115	COG3764	Sortase (surface protein transpeptidase)
MNA02_RS06135	COG0488	(ABC) transporter
MNA02_RS06165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MNA02_RS06170	COG1328	CTP reductase activity
MNA02_RS06170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MNA02_RS06205	COG1196	nuclear chromosome segregation
MNA02_RS06220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MNA02_RS06240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNA02_RS06250	COG1011	Hydrolase
MNA02_RS06255	COG1760	l-serine dehydratase
MNA02_RS06280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MNA02_RS06290	COG2197	response regulator
MNA02_RS06295	COG4585	Histidine kinase
MNA02_RS06305	COG1131	(ABC) transporter
MNA02_RS06355	COG1131	(ABC) transporter
MNA02_RS06375	COG0577	efflux transmembrane transporter activity
MNA02_RS06380	COG1136	(ABC) transporter
MNA02_RS06385	COG5002	protein histidine kinase activity
MNA02_RS06385	COG2198	Histidine kinase
MNA02_RS06385	COG0784	Response regulator, receiver
MNA02_RS06390	COG0745	RESPONSE REGULATOR receiver
MNA02_RS06400	COG2233	PERMEase
MNA02_RS06405	COG2233	PERMEase
MNA02_RS06410	COG0534	Mate efflux family protein
MNA02_RS06415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MNA02_RS06415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MNA02_RS06425	COG1482	cell wall glycoprotein biosynthetic process
MNA02_RS06430	COG1482	cell wall glycoprotein biosynthetic process
MNA02_RS06440	COG0531	amino acid
MNA02_RS06450	COG2514	catechol 2,3-dioxygenase activity
MNA02_RS06455	COG1959	2 iron, 2 sulfur cluster binding
MNA02_RS06465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MNA02_RS06470	COG0778	Nitroreductase
MNA02_RS06480	COG0656	L-ascorbic acid biosynthetic process
MNA02_RS06485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MNA02_RS06525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MNA02_RS06550	COG1280	lysine exporter protein (LysE YggA)
MNA02_RS06560	COG1442	glycosyl transferase family 8
MNA02_RS06560	COG1216	Glycosyl transferase, family 2
MNA02_RS06565	COG0577	efflux transmembrane transporter activity
MNA02_RS06610	COG1396	sequence-specific DNA binding
MNA02_RS06615	COG2801	Transposase and inactivated derivatives
MNA02_RS06630	COG0419	ATPase involved in DNA repair
MNA02_RS06635	COG0420	3'-5' exonuclease activity
MNA02_RS06640	COG3250	beta-galactosidase activity
MNA02_RS06645	COG2211	Major facilitator Superfamily
MNA02_RS06645	COG2190	(PTS) system
MNA02_RS06650	COG2017	converts alpha-aldose to the beta-anomer
MNA02_RS06655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MNA02_RS06670	COG1609	Transcriptional regulator
MNA02_RS06685	COG3064	Membrane
MNA02_RS06690	COG0488	(ABC) transporter
MNA02_RS06750	COG2197	response regulator
MNA02_RS06755	COG4585	Histidine kinase
MNA02_RS06765	COG0515	serine threonine protein kinase
MNA02_RS06765	COG2815	serine threonine protein kinase
MNA02_RS06775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MNA02_RS06775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MNA02_RS06785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MNA02_RS06800	COG0552	protein localization to endoplasmic reticulum
MNA02_RS06805	COG0561	phosphatase activity
MNA02_RS06810	COG0561	phosphatase activity
MNA02_RS06815	COG1725	Transcriptional regulator
MNA02_RS06820	COG1131	(ABC) transporter
MNA02_RS06830	COG4608	Belongs to the ABC transporter superfamily
MNA02_RS06835	COG0444	Belongs to the ABC transporter superfamily
MNA02_RS06840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MNA02_RS06845	COG0601	transmembrane transport
MNA02_RS06850	COG4166	transmembrane transport
MNA02_RS06860	COG4166	transmembrane transport
MNA02_RS06870	COG2801	Transposase and inactivated derivatives
MNA02_RS06875	COG4608	Belongs to the ABC transporter superfamily
MNA02_RS06880	COG4608	Belongs to the ABC transporter superfamily
MNA02_RS06885	COG0084	hydrolase, TatD family'
MNA02_RS06890	COG2223	nitrite transmembrane transporter activity
MNA02_RS06895	COG2801	Transposase and inactivated derivatives
MNA02_RS06905	COG0280	phosphate acetyltransferase
MNA02_RS06910	COG0564	pseudouridine synthase activity
MNA02_RS06920	COG2357	RelA SpoT domain protein
MNA02_RS06935	COG1104	cysteine desulfurase activity
MNA02_RS06950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MNA02_RS06955	COG2003	Belongs to the UPF0758 family
MNA02_RS06980	COG1215	transferase activity, transferring glycosyl groups
MNA02_RS06995	COG1216	Glycosyl transferase, family 2
MNA02_RS06995	COG1442	glycosyl transferase family 8
MNA02_RS07015	COG1091	dTDP-4-dehydrorhamnose reductase activity
MNA02_RS07025	COG0463	Glycosyl transferase, family 2
MNA02_RS07030	COG2151	metal-sulfur cluster biosynthetic enzyme
MNA02_RS07035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MNA02_RS07040	COG0358	DNA primase activity
MNA02_RS07045	COG1970	mechanosensitive ion channel activity
MNA02_RS07055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNA02_RS07060	COG0436	Aminotransferase
MNA02_RS07065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNA02_RS07070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNA02_RS07075	COG1051	belongs to the nudix hydrolase family
MNA02_RS07100	COG0765	amino acid transport
MNA02_RS07105	COG1126	abc transporter atp-binding protein
MNA02_RS07120	COG1187	pseudouridine synthase activity
MNA02_RS07165	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNA02_RS07170	COG1518	maintenance of DNA repeat elements
MNA02_RS07175	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MNA02_RS07180	COG0560	Phosphoserine phosphatase
MNA02_RS07190	COG0187	DNA topoisomerase II activity
MNA02_RS07200	COG1346	cytolysis
MNA02_RS07205	COG1380	Effector of murein hydrolase LrgA
MNA02_RS07215	COG1393	Belongs to the ArsC family
MNA02_RS07225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MNA02_RS07265	COG1177	transmembrane transport
MNA02_RS07270	COG1176	ABC-type spermidine putrescine transport system, permease component I
MNA02_RS07310	COG0531	amino acid
MNA02_RS07315	COG0285	dihydrofolate synthase activity
MNA02_RS07320	COG1837	Belongs to the UPF0109 family
MNA02_RS07330	COG3615	Tellurite resistance protein tehB
MNA02_RS07330	COG0500	methyltransferase
MNA02_RS07340	COG0708	Exodeoxyribonuclease III
MNA02_RS07355	COG1597	lipid kinase activity
MNA02_RS07365	COG4708	membrane
MNA02_RS07375	COG0024	Methionine aminopeptidase
MNA02_RS07380	COG4109	DRTGG domain
MNA02_RS07390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNA02_RS07395	COG2333	competence protein COMEC
MNA02_RS07395	COG0658	competence protein
MNA02_RS07400	COG1596	polysaccharide export
MNA02_RS07400	COG1555	photosystem II stabilization
MNA02_RS07405	COG0204	Acyl-transferase
MNA02_RS07410	COG0726	polysaccharide deacetylase
MNA02_RS07415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MNA02_RS07425	COG0513	Belongs to the DEAD box helicase family
MNA02_RS07445	COG1396	sequence-specific DNA binding
MNA02_RS07450	COG2211	Major facilitator Superfamily
MNA02_RS07465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MNA02_RS07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNA02_RS07485	COG1126	abc transporter atp-binding protein
MNA02_RS07490	COG0765	amino acid transport
MNA02_RS07495	COG0765	amino acid transport
MNA02_RS07510	COG2217	Heavy metal translocating P-type atpase
MNA02_RS07520	COG0159	tryptophan synthase activity
MNA02_RS07530	COG0135	phosphoribosylanthranilate isomerase activity
MNA02_RS07545	COG0512	Glutamine amidotransferase of anthranilate synthase
MNA02_RS07550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MNA02_RS07555	COG1605	Chorismate mutase
MNA02_RS07555	COG0287	Prephenate dehydrogenase
MNA02_RS07565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MNA02_RS07590	COG2176	DNA-directed DNA polymerase activity
MNA02_RS07600	COG2151	metal-sulfur cluster biosynthetic enzyme
MNA02_RS07610	COG2081	HI0933 family
MNA02_RS07635	COG1131	(ABC) transporter
MNA02_RS07640	COG0537	adenosine 5'-monophosphoramidase activity
MNA02_RS07670	COG2226	methyltransferase
MNA02_RS07675	COG0799	negative regulation of ribosome biogenesis
MNA02_RS07680	COG1713	HD superfamily hydrolase involved in NAD metabolism
MNA02_RS07685	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MNA02_RS07690	COG1534	Rna-binding protein
MNA02_RS07695	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MNA02_RS07700	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MNA02_RS07735	COG2723	6-phospho-beta-galactosidase activity
MNA02_RS07750	COG1335	isochorismatase
MNA02_RS07760	COG0436	Aminotransferase
MNA02_RS07765	COG0589	response to stress
MNA02_RS07780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MNA02_RS07785	COG1253	flavin adenine dinucleotide binding
MNA02_RS07790	COG1119	ATPase activity
MNA02_RS07795	COG0025	NhaP-type Na H and K H
MNA02_RS07805	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MNA02_RS07810	COG1242	4 iron, 4 sulfur cluster binding
MNA02_RS07815	COG3480	Lon protease (S16) C-terminal proteolytic domain
MNA02_RS07820	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MNA02_RS07825	COG0742	ribosomal rna small subunit methyltransferase
MNA02_RS07830	COG0492	ferredoxin-NADP+ reductase activity
MNA02_RS07840	COG1126	abc transporter atp-binding protein
MNA02_RS07850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNA02_RS07865	COG1882	Formate acetyltransferase
MNA02_RS07895	COG0390	transport system, permease component
MNA02_RS07900	COG4619	ABC transporter
MNA02_RS07905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MNA02_RS07920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MNA02_RS07955	COG2801	Transposase and inactivated derivatives
MNA02_RS08010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MNA02_RS08020	COG1132	(ABC) transporter
MNA02_RS08025	COG1132	(ABC) transporter
MNA02_RS08040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MNA02_RS08045	COG4470	Protein conserved in bacteria
MNA02_RS08050	COG0737	Belongs to the 5'-nucleotidase family
MNA02_RS08055	COG0513	Belongs to the DEAD box helicase family
MNA02_RS08065	COG0768	penicillin binding
MNA02_RS08100	COG3152	Membrane
MNA02_RS08110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MNA02_RS08125	COG4152	abc transporter atp-binding protein
MNA02_RS08130	COG1811	Na channel or pump
MNA02_RS08170	COG0561	phosphatase activity
MNA02_RS08175	COG0252	asparaginase activity
MNA02_RS08180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MNA02_RS08185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MNA02_RS08195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MNA02_RS08200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MNA02_RS08215	COG1482	cell wall glycoprotein biosynthetic process
MNA02_RS08220	COG1940	carbohydrate kinase activity
MNA02_RS08225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNA02_RS08225	COG2190	(PTS) system
MNA02_RS08225	COG1263	PTS System
MNA02_RS08230	COG1621	beta-fructofuranosidase activity
MNA02_RS08235	COG1609	Transcriptional regulator
MNA02_RS08255	COG2131	deaminase
MNA02_RS08260	COG0006	proline dipeptidase activity
MNA02_RS08275	COG1131	(ABC) transporter
MNA02_RS08350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MNA02_RS08350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MNA02_RS08375	COG0681	Belongs to the peptidase S26 family
MNA02_RS08380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MNA02_RS08400	COG0456	acetyltransferase
MNA02_RS08405	COG1214	PFAM Peptidase M22, glycoprotease
MNA02_RS08425	COG0174	glutamine synthetase
MNA02_RS08430	COG0789	Transcriptional regulator
MNA02_RS08470	COG2801	Transposase and inactivated derivatives
MNA02_RS08505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MNA02_RS08550	COG0084	hydrolase, TatD family'
MNA02_RS08555	COG1832	CoA-binding protein
MNA02_RS08560	COG3118	belongs to the thioredoxin family
MNA02_RS08625	COG0706	membrane insertase activity
MNA02_RS08690	COG0756	dUTP diphosphatase activity
MNA02_RS08725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MNA02_RS08730	COG0457	Tetratricopeptide repeat
MNA02_RS08730	COG0705	Rhomboid family
MNA02_RS08735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MNA02_RS08755	COG2226	methyltransferase
MNA02_RS08780	COG0425	Belongs to the sulfur carrier protein TusA family
MNA02_RS08785	COG2391	methyltransferase activity
MNA02_RS08790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNA02_RS08795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MNA02_RS08805	COG1363	Peptidase, m42
MNA02_RS08810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MNA02_RS08815	COG1266	CAAX protease self-immunity
MNA02_RS08875	COG1459	type II secretion system
MNA02_RS08880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MNA02_RS08915	COG0440	acetolactate synthase activity
MNA02_RS08920	COG0028	Belongs to the TPP enzyme family
MNA02_RS08925	COG0129	dihydroxy-acid dehydratase activity
MNA02_RS08930	COG1461	Dihydroxyacetone kinase
MNA02_RS08940	COG0534	Mate efflux family protein
MNA02_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
MNA02_RS08965	COG1454	alcohol dehydrogenase
MNA02_RS08970	COG1012	belongs to the aldehyde dehydrogenase family
MNA02_RS08970	COG1454	alcohol dehydrogenase
MNA02_RS08975	COG1454	alcohol dehydrogenase
MNA02_RS08975	COG1012	belongs to the aldehyde dehydrogenase family
MNA02_RS08980	COG3590	peptidase
MNA02_RS08985	COG0366	Alpha amylase catalytic
MNA02_RS08990	COG0366	Alpha amylase catalytic
MNA02_RS08995	COG0366	Alpha amylase catalytic
MNA02_RS09005	COG1609	Transcriptional regulator
MNA02_RS09010	COG2188	Transcriptional regulator
MNA02_RS09015	COG4475	Protein of unknown function (DUF436)
MNA02_RS09050	COG0640	Transcriptional regulator
MNA02_RS09055	COG2217	Heavy metal translocating P-type atpase
MNA02_RS09080	COG3328	transposase activity
MNA02_RS09085	COG0582	viral genome integration into host DNA
MNA02_RS09090	COG0191	fructose-bisphosphate aldolase activity
MNA02_RS09150	COG0201	protein transport
MNA02_RS09295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MNA02_RS09305	COG3328	transposase activity
MNA02_RS09315	COG0515	serine threonine protein kinase
MNA02_RS09330	COG1132	(ABC) transporter
MNA02_RS09335	COG1396	sequence-specific DNA binding
MNA02_RS09345	COG1132	(ABC) transporter
MNA02_RS09380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MNA02_RS09420	COG0602	queuosine metabolic process
MNA02_RS09430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MNA02_RS09455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MNA02_RS09465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MNA02_RS09495	COG3328	transposase activity
MNA02_RS09500	COG2261	transglycosylase associated protein
MNA02_RS09520	COG3237	CsbD-like
MNA02_RS09530	COG3328	transposase activity
MNA02_RS09550	COG1511	domain protein
MNA02_RS09550	COG1511	domain protein
MNA02_RS09560	COG3759	membrane
MNA02_RS09575	COG0305	Participates in initiation and elongation during chromosome replication
MNA02_RS09595	COG0494	nUDIX hydrolase
MNA02_RS09610	COG0741	lytic transglycosylase activity
MNA02_RS09615	COG3584	3D domain protein
MNA02_RS09615	COG1388	LysM domain
MNA02_RS09620	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNA02_RS09635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MNA02_RS09645	COG0612	Peptidase, M16
MNA02_RS09675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MNA02_RS09680	COG0488	(ABC) transporter
MNA02_RS09715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MNA02_RS09720	COG1475	DNA binding
MNA02_RS09730	COG0588	phosphoglycerate mutase activity
MNA02_RS09755	COG4166	transmembrane transport
MNA02_RS09760	COG4166	transmembrane transport