locus-tag	class	description
STND_RS00010	COG0592	DNA-directed DNA polymerase activity
STND_RS00020	COG0012	GTP binding
STND_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
STND_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
STND_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STND_RS00085	COG2801	Transposase and inactivated derivatives
STND_RS00205	COG3942	CHAP domain
STND_RS00220	COG0436	Aminotransferase
STND_RS00235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STND_RS00245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
STND_RS00260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
STND_RS00280	COG2801	Transposase and inactivated derivatives
STND_RS00285	COG1388	LysM domain
STND_RS00285	COG3942	CHAP domain
STND_RS00290	COG0151	Belongs to the GarS family
STND_RS00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STND_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STND_RS00370	COG4550	Control of competence regulator ComK, YlbF/YmcA
STND_RS00410	COG2818	Glycosylase
STND_RS00420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
STND_RS00425	COG1393	Belongs to the ArsC family
STND_RS00515	COG2309	aminopeptidase activity
STND_RS00530	COG0431	NADPH-dependent FMN reductase
STND_RS00535	COG2801	Transposase and inactivated derivatives
STND_RS00570	COG4463	regulation of RNA biosynthetic process
STND_RS00575	COG0542	response to heat
STND_RS00585	COG1686	Belongs to the peptidase S11 family
STND_RS00600	COG1045	serine acetyltransferase
STND_RS00610	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
STND_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STND_RS00650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
STND_RS00705	COG1705	Flagellar rod assembly protein muramidase FlgJ
STND_RS00705	COG3942	CHAP domain
STND_RS00720	COG3830	Belongs to the UPF0237 family
STND_RS00735	COG1876	peptidase activity
STND_RS00770	COG0351	phosphomethylpyrimidine kinase
STND_RS00805	COG4166	transmembrane transport
STND_RS00830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
STND_RS00845	COG0668	transmembrane transport
STND_RS00860	COG0504	CTP synthase activity
STND_RS00870	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
STND_RS00880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
STND_RS00885	COG0737	Belongs to the 5'-nucleotidase family
STND_RS00895	COG0737	Belongs to the 5'-nucleotidase family
STND_RS00900	COG0737	Belongs to the 5'-nucleotidase family
STND_RS00940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
STND_RS00970	COG1126	abc transporter atp-binding protein
STND_RS00975	COG0765	amino acid transport
STND_RS00980	COG1968	undecaprenyl-diphosphatase activity
STND_RS00990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STND_RS01000	COG0719	Fe-S assembly protein
STND_RS01005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
STND_RS01015	COG0719	Fe-S assembly protein
STND_RS01020	COG4166	transmembrane transport
STND_RS01025	COG0601	transmembrane transport
STND_RS01045	COG0444	Belongs to the ABC transporter superfamily
STND_RS01050	COG0444	Belongs to the ABC transporter superfamily
STND_RS01070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
STND_RS01085	COG1121	(ABC) transporter
STND_RS01090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
STND_RS01100	COG2190	(PTS) system
STND_RS01100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STND_RS01100	COG1263	PTS System
STND_RS01105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STND_RS01105	COG1263	PTS System
STND_RS01105	COG2190	(PTS) system
STND_RS01110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STND_RS01110	COG1263	PTS System
STND_RS01110	COG2190	(PTS) system
STND_RS01140	COG4589	Belongs to the CDS family
STND_RS01155	COG4120	Belongs to the binding-protein-dependent transport system permease family
STND_RS01160	COG1116	anion transmembrane transporter activity
STND_RS01160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
STND_RS01205	COG0564	pseudouridine synthase activity
STND_RS01210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STND_RS01235	COG1349	DNA-binding transcription factor activity
STND_RS01265	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
STND_RS01280	COG3579	cysteine-type endopeptidase activity
STND_RS01290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
STND_RS01310	COG0116	Belongs to the methyltransferase superfamily
STND_RS01320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
STND_RS01340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
STND_RS01365	COG1254	Belongs to the acylphosphatase family
STND_RS01370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STND_RS01415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
STND_RS01435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
STND_RS01440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
STND_RS01445	COG1187	pseudouridine synthase activity
STND_RS01455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STND_RS01460	COG0569	domain protein
STND_RS01470	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
STND_RS01475	COG0671	phosphoesterase, PA-phosphatase related
STND_RS01495	COG2274	protein secretion by the type I secretion system
STND_RS01500	COG2274	protein secretion by the type I secretion system
STND_RS01505	COG2274	protein secretion by the type I secretion system
STND_RS01555	COG0829	nickel cation binding
STND_RS01560	COG0310	cobalt ion transport
STND_RS01570	COG1122	ATPase activity
STND_RS01575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS01580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
STND_RS01600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS01605	COG1464	Belongs to the NlpA lipoprotein family
STND_RS01615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
STND_RS01640	COG1122	ATPase activity
STND_RS01650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
STND_RS01660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STND_RS01675	COG0745	RESPONSE REGULATOR receiver
STND_RS01680	COG5002	protein histidine kinase activity
STND_RS01695	COG1484	DNA-dependent DNA replication
STND_RS01710	COG2801	Transposase and inactivated derivatives
STND_RS01740	COG3716	PTS system mannose fructose sorbose family IID component
STND_RS01745	COG3715	PTS system
STND_RS01755	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
STND_RS01760	COG0561	phosphatase activity
STND_RS01765	COG2252	PERMEase
STND_RS01770	COG0802	atpase or kinase
STND_RS01775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
STND_RS01780	COG1316	TRANSCRIPTIONal
STND_RS01790	COG0195	Participates in both transcription termination and antitermination
STND_RS01795	COG2740	Nucleic-acid-binding protein implicated in transcription termination
STND_RS01815	COG1611	Belongs to the LOG family
STND_RS01835	COG2244	polysaccharide biosynthetic process
STND_RS01840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STND_RS01845	COG0626	cystathionine gamma-synthase activity
STND_RS01850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
STND_RS01875	COG4471	UPF0298 protein
STND_RS01885	COG0559	Belongs to the binding-protein-dependent transport system permease family
STND_RS01905	COG0517	IMP dehydrogenase activity
STND_RS01920	COG1739	Uncharacterized protein family UPF0029
STND_RS01925	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
STND_RS01930	COG1040	competence protein
STND_RS02020	COG0527	aspartate kinase activity
STND_RS02025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STND_RS02030	COG1024	Enoyl-CoA hydratase
STND_RS02035	COG1846	Transcriptional regulator
STND_RS02055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
STND_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
STND_RS02065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STND_RS02080	COG0439	Biotin carboxylase
STND_RS02105	COG0076	glutamate decarboxylase activity
STND_RS02110	COG0531	amino acid
STND_RS02155	COG2801	Transposase and inactivated derivatives
STND_RS02160	COG2963	transposase activity
STND_RS02175	COG1349	DNA-binding transcription factor activity
STND_RS02180	COG1105	Belongs to the carbohydrate kinase PfkB family
STND_RS02185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STND_RS02185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
STND_RS02185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
STND_RS02190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STND_RS02195	COG0285	dihydrofolate synthase activity
STND_RS02205	COG1104	cysteine desulfurase activity
STND_RS02270	COG0488	(ABC) transporter
STND_RS02290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STND_RS02295	COG0242	peptide deformylase activity
STND_RS02355	COG1702	phosphate starvation-inducible protein PhoH
STND_RS02375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STND_RS02375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STND_RS02400	COG4122	O-methyltransferase activity
STND_RS02405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
STND_RS02430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
STND_RS02435	COG0436	Aminotransferase
STND_RS02450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
STND_RS02455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
STND_RS02460	COG0726	polysaccharide deacetylase
STND_RS02475	COG2962	Rard protein
STND_RS02515	COG0356	it plays a direct role in the translocation of protons across the membrane
STND_RS02550	COG0772	Belongs to the SEDS family
STND_RS02570	COG0470	DNA polymerase III
STND_RS02575	COG1774	PSP1 C-terminal conserved region
STND_RS02580	COG4467	Involved in initiation control of chromosome replication
STND_RS02590	COG0004	ammonium transporteR
STND_RS02595	COG0347	Belongs to the P(II) protein family
STND_RS02600	COG1705	Flagellar rod assembly protein muramidase FlgJ
STND_RS02600	COG1388	LysM domain
STND_RS02655	COG1113	amino acid transport
STND_RS02665	COG2190	(PTS) system
STND_RS02665	COG1263	PTS System
STND_RS02665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STND_RS02680	COG2801	Transposase and inactivated derivatives
STND_RS02710	COG0583	DNA-binding transcription factor activity
STND_RS02720	COG0564	pseudouridine synthase activity
STND_RS02740	COG0505	Belongs to the CarA family
STND_RS02775	COG0577	efflux transmembrane transporter activity
STND_RS02790	COG3328	transposase activity
STND_RS02820	COG3279	Response regulator of the LytR AlgR family
STND_RS02830	COG1131	(ABC) transporter
STND_RS02865	COG1187	pseudouridine synthase activity
STND_RS02870	COG1473	amidohydrolase
STND_RS02875	COG0686	Belongs to the AlaDH PNT family
STND_RS02880	COG0686	Belongs to the AlaDH PNT family
STND_RS02885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STND_RS02950	COG0438	transferase activity, transferring glycosyl groups
STND_RS02980	COG1272	protein, Hemolysin III
STND_RS02995	COG3425	synthase
STND_RS03005	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
STND_RS03025	COG0833	amino acid
STND_RS03030	COG2040	homocysteine
STND_RS03050	COG0187	DNA topoisomerase II activity
STND_RS03060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STND_RS03080	COG0539	negative regulation of cytoplasmic translation
STND_RS03110	COG0673	inositol 2-dehydrogenase activity
STND_RS03125	COG0494	nUDIX hydrolase
STND_RS03130	COG0542	response to heat
STND_RS03135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
STND_RS03140	COG4703	Protein of unknown function (DUF1797)
STND_RS03145	COG0765	amino acid transport
STND_RS03195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STND_RS03200	COG0768	penicillin binding
STND_RS03205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
STND_RS03215	COG3711	transcriptional antiterminator
STND_RS03225	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
STND_RS03230	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
STND_RS03235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
STND_RS03240	COG0237	dephospho-CoA kinase activity
STND_RS03245	COG2814	Major facilitator Superfamily
STND_RS03255	COG0557	exoribonuclease II activity
STND_RS03270	COG1185	polyribonucleotide nucleotidyltransferase activity
STND_RS03275	COG0006	proline dipeptidase activity
STND_RS03280	COG1609	Transcriptional regulator
STND_RS03310	COG1368	sulfuric ester hydrolase activity
STND_RS03315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
STND_RS03340	COG0287	Prephenate dehydrogenase
STND_RS03365	COG0077	Prephenate dehydratase
STND_RS03425	COG1518	maintenance of DNA repeat elements
STND_RS03430	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STND_RS03440	COG3689	TIGRFAM TIGR03943 family protein
STND_RS03445	COG0701	Predicted permease
STND_RS03450	COG2183	response to ionizing radiation
STND_RS03495	COG0826	peptidase U32
STND_RS03500	COG1268	BioY protein
STND_RS03510	COG4443	Transcriptional Coactivator p15 (PC4)
STND_RS03515	COG1914	H( )-stimulated, divalent metal cation uptake system
STND_RS03550	COG1705	Flagellar rod assembly protein muramidase FlgJ
STND_RS03550	COG1388	LysM domain
STND_RS03565	COG0406	alpha-ribazole phosphatase activity
STND_RS03570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
STND_RS03600	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
STND_RS03610	COG0732	type I restriction modification DNA specificity domain
STND_RS03625	COG1704	LemA family
STND_RS03630	COG0501	Belongs to the peptidase M48B family
STND_RS03655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
STND_RS03670	COG0783	Belongs to the Dps family
STND_RS03675	COG0735	belongs to the Fur family
STND_RS03680	COG4483	Protein conserved in bacteria
STND_RS03685	COG1940	carbohydrate kinase activity
STND_RS03690	COG1217	gtp-binding protein TYPA
STND_RS03715	COG0849	cell division
STND_RS03725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STND_RS03745	COG3599	regulation of cell shape
STND_RS03780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STND_RS03785	COG0625	glutathione transferase activity
STND_RS03790	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
STND_RS03805	COG2890	protein-(glutamine-N5) methyltransferase activity
STND_RS03835	COG1132	(ABC) transporter
STND_RS03850	COG1696	Membrane protein involved in D-alanine export
STND_RS03860	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
STND_RS03870	COG2801	Transposase and inactivated derivatives
STND_RS03875	COG2801	Transposase and inactivated derivatives
STND_RS03890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STND_RS03895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STND_RS03960	COG1396	sequence-specific DNA binding
STND_RS03965	COG0582	viral genome integration into host DNA
STND_RS03985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STND_RS03990	COG4684	Psort location CytoplasmicMembrane, score
STND_RS03995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
STND_RS04020	COG5002	protein histidine kinase activity
STND_RS04035	COG2801	Transposase and inactivated derivatives
STND_RS04050	COG2813	Specifically methylates the guanine in position
STND_RS04070	COG0295	cytidine deaminase activity
STND_RS04075	COG1744	ABC transporter substrate-binding protein PnrA-like
STND_RS04080	COG3845	ABC transporter
STND_RS04085	COG4603	Belongs to the binding-protein-dependent transport system permease family
STND_RS04090	COG1079	Belongs to the binding-protein-dependent transport system permease family
STND_RS04100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
STND_RS04100	COG1199	ATP-dependent helicase activity
STND_RS04110	COG0436	Aminotransferase
STND_RS04140	COG0251	oxidation-reduction process
STND_RS04150	COG0720	synthase
STND_RS04200	COG1278	Cold shock
STND_RS04220	COG2217	Heavy metal translocating P-type atpase
STND_RS04235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
STND_RS04240	COG0626	cystathionine gamma-synthase activity
STND_RS04245	COG1045	serine acetyltransferase
STND_RS04250	COG3328	transposase activity
STND_RS04255	COG4975	Glucose uptake
STND_RS04275	COG3443	Belongs to the bacterial solute-binding protein 9 family
STND_RS04275	COG0803	Belongs to the bacterial solute-binding protein 9 family
STND_RS04295	COG3942	CHAP domain
STND_RS04295	COG1705	Flagellar rod assembly protein muramidase FlgJ
STND_RS04310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
STND_RS04315	COG2824	Alkylphosphonate utilization operon protein PhnA
STND_RS04320	COG0765	amino acid transport
STND_RS04325	COG1126	abc transporter atp-binding protein
STND_RS04330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS04340	COG1064	alcohol dehydrogenase
STND_RS04345	COG1064	alcohol dehydrogenase
STND_RS04355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
STND_RS04355	COG0519	Catalyzes the synthesis of GMP from XMP
STND_RS04360	COG2188	Transcriptional regulator
STND_RS04370	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STND_RS04380	COG1827	regulation of RNA biosynthetic process
STND_RS04390	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STND_RS04400	COG1940	carbohydrate kinase activity
STND_RS04405	COG0758	DNA mediated transformation
STND_RS04410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
STND_RS04455	COG0481	GTPase activity
STND_RS04460	COG1396	sequence-specific DNA binding
STND_RS04470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
STND_RS04475	COG0010	Belongs to the arginase family
STND_RS04485	COG0028	Belongs to the TPP enzyme family
STND_RS04490	COG3527	Alpha-acetolactate decarboxylase
STND_RS04520	COG1230	cation diffusion facilitator family transporter
STND_RS04530	COG1063	alcohol dehydrogenase
STND_RS04560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
STND_RS04565	COG4607	ABC-type enterochelin transport system periplasmic component
STND_RS04585	COG1293	RNA-binding protein homologous to eukaryotic snRNP
STND_RS04615	COG0047	phosphoribosylformylglycinamidine synthase activity
STND_RS04625	COG0167	dihydroorotate dehydrogenase activity
STND_RS04635	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STND_RS04655	COG1337	RAMP superfamily
STND_RS04660	COG1567	CRISPR-associated RAMP protein, Csm4 family
STND_RS04675	COG0284	orotidine-5'-phosphate decarboxylase activity
STND_RS04690	COG3104	oligopeptide transport
STND_RS04695	COG0154	amidase activity
STND_RS04700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS04705	COG0765	amino acid transport
STND_RS04715	COG0737	Belongs to the 5'-nucleotidase family
STND_RS04745	COG1115	amino acid carrier protein
STND_RS04755	COG2873	o-acetylhomoserine
STND_RS04785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
STND_RS04790	COG0196	riboflavin kinase activity
STND_RS04795	COG1393	Belongs to the ArsC family
STND_RS04805	COG0483	inositol monophosphate 1-phosphatase activity
STND_RS04810	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
STND_RS04810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STND_RS04820	COG0573	inorganic phosphate transmembrane transporter activity
STND_RS04825	COG0581	inorganic phosphate transmembrane transporter activity
STND_RS04840	COG0704	Plays a role in the regulation of phosphate uptake
STND_RS04855	COG0095	Lipoate-protein ligase
STND_RS04870	COG0058	SHG alpha-glucan phosphorylase activity
STND_RS04875	COG1640	4-alpha-glucanotransferase
STND_RS04890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
STND_RS04895	COG0805	protein transport
STND_RS04900	COG0672	)-iron permease
STND_RS04905	COG2837	iron assimilation
STND_RS04910	COG2822	iron ion transport
STND_RS04920	COG1523	belongs to the glycosyl hydrolase 13 family
STND_RS04930	COG1523	belongs to the glycosyl hydrolase 13 family
STND_RS04955	COG0508	dehydrogenase complex catalyzes the overall conversion of
STND_RS04960	COG0022	dehydrogenase e1 component
STND_RS04960	COG0508	dehydrogenase complex catalyzes the overall conversion of
STND_RS04965	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STND_RS05000	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
STND_RS05005	COG4667	esterase of the alpha-beta hydrolase superfamily
STND_RS05040	COG0628	permease
STND_RS05060	COG0561	phosphatase activity
STND_RS05105	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
STND_RS05115	COG2963	transposase activity
STND_RS05135	COG2244	polysaccharide biosynthetic process
STND_RS05150	COG1442	glycosyl transferase family 8
STND_RS05150	COG1216	Glycosyl transferase, family 2
STND_RS05200	COG1316	TRANSCRIPTIONal
STND_RS05225	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
STND_RS05230	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
STND_RS05250	COG1573	uracil-dna glycosylase
STND_RS05315	COG0681	Belongs to the peptidase S26 family
STND_RS05325	COG0628	permease
STND_RS05330	COG1051	belongs to the nudix hydrolase family
STND_RS05335	COG2177	Part of the ABC transporter FtsEX involved in
STND_RS05340	COG2884	Cell division ATP-binding protein ftsE
STND_RS05345	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STND_RS05350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
STND_RS05385	COG2348	transferase activity, transferring amino-acyl groups
STND_RS05395	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
STND_RS05400	COG5002	protein histidine kinase activity
STND_RS05405	COG0745	RESPONSE REGULATOR receiver
STND_RS05410	COG1126	abc transporter atp-binding protein
STND_RS05415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS05420	COG0765	amino acid transport
STND_RS05425	COG0765	amino acid transport
STND_RS05450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STND_RS05500	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
STND_RS05505	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
STND_RS05505	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
STND_RS05515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
STND_RS05520	COG1956	GAF domain-containing protein
STND_RS05525	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
STND_RS05555	COG0335	large ribosomal subunit rRNA binding
STND_RS05570	COG0038	chloride channel
STND_RS05575	COG0716	FMN binding
STND_RS05640	COG3328	transposase activity
STND_RS05655	COG0469	pyruvate kinase activity
STND_RS05705	COG0167	dihydroorotate dehydrogenase activity
STND_RS05715	COG0776	regulation of translation
STND_RS05725	COG2755	lipolytic protein G-D-S-L family
STND_RS05730	COG1307	EDD domain protein, DegV family
STND_RS05735	COG0497	DNA recombination
STND_RS05740	COG1438	arginine binding
STND_RS05745	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
STND_RS05770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STND_RS05790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
STND_RS05790	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
STND_RS05795	COG0300	oxidoreductase activity
STND_RS05810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
STND_RS05815	COG0772	Belongs to the SEDS family
STND_RS05830	COG0107	imidazoleglycerol-phosphate synthase activity
STND_RS05840	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
STND_RS05850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
STND_RS05875	COG2801	Transposase and inactivated derivatives
STND_RS05910	COG0647	UMP catabolic process
STND_RS05920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
STND_RS05940	COG1088	dTDP-glucose 4,6-dehydratase activity
STND_RS05950	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
STND_RS05955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
STND_RS05970	COG2384	SAM-dependent methyltransferase
STND_RS05995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STND_RS06000	COG3442	glutamine amidotransferase
STND_RS06005	COG0392	lysyltransferase activity
STND_RS06005	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
STND_RS06020	COG0488	(ABC) transporter
STND_RS06030	COG0513	Belongs to the DEAD box helicase family
STND_RS06065	COG0372	Belongs to the citrate synthase family
STND_RS06070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
STND_RS06075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
STND_RS06080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STND_RS06085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STND_RS06115	COG3764	Sortase (surface protein transpeptidase)
STND_RS06135	COG0488	(ABC) transporter
STND_RS06165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
STND_RS06170	COG1328	CTP reductase activity
STND_RS06170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
STND_RS06205	COG1196	nuclear chromosome segregation
STND_RS06220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STND_RS06240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
STND_RS06250	COG1011	Hydrolase
STND_RS06255	COG1268	BioY protein
STND_RS06265	COG0517	IMP dehydrogenase activity
STND_RS06265	COG1125	glycine betaine transport
STND_RS06280	COG2986	histidine ammonia-lyase
STND_RS06290	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
STND_RS06295	COG2197	response regulator
STND_RS06300	COG4585	Histidine kinase
STND_RS06310	COG1131	(ABC) transporter
STND_RS06325	COG0385	Bile acid
STND_RS06340	COG1131	(ABC) transporter
STND_RS06360	COG0577	efflux transmembrane transporter activity
STND_RS06365	COG1136	(ABC) transporter
STND_RS06370	COG0784	Response regulator, receiver
STND_RS06370	COG2205	protein histidine kinase activity
STND_RS06375	COG0745	RESPONSE REGULATOR receiver
STND_RS06385	COG2233	PERMEase
STND_RS06390	COG2233	PERMEase
STND_RS06395	COG0534	Mate efflux family protein
STND_RS06400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STND_RS06400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
STND_RS06410	COG1482	cell wall glycoprotein biosynthetic process
STND_RS06415	COG1482	cell wall glycoprotein biosynthetic process
STND_RS06425	COG0531	amino acid
STND_RS06435	COG2514	catechol 2,3-dioxygenase activity
STND_RS06440	COG1959	2 iron, 2 sulfur cluster binding
STND_RS06450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
STND_RS06455	COG0778	Nitroreductase
STND_RS06465	COG0656	L-ascorbic acid biosynthetic process
STND_RS06470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STND_RS06485	COG0745	RESPONSE REGULATOR receiver
STND_RS06510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
STND_RS06530	COG1280	lysine exporter protein (LysE YggA)
STND_RS06540	COG1442	glycosyl transferase family 8
STND_RS06540	COG1216	Glycosyl transferase, family 2
STND_RS06545	COG0577	efflux transmembrane transporter activity
STND_RS06590	COG1396	sequence-specific DNA binding
STND_RS06595	COG2801	Transposase and inactivated derivatives
STND_RS06610	COG0419	ATPase involved in DNA repair
STND_RS06615	COG0420	3'-5' exonuclease activity
STND_RS06620	COG3250	beta-galactosidase activity
STND_RS06625	COG2211	Major facilitator Superfamily
STND_RS06625	COG2190	(PTS) system
STND_RS06630	COG2017	converts alpha-aldose to the beta-anomer
STND_RS06635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
STND_RS06650	COG1609	Transcriptional regulator
STND_RS06665	COG3064	Membrane
STND_RS06670	COG0488	(ABC) transporter
STND_RS06730	COG2197	response regulator
STND_RS06735	COG4585	Histidine kinase
STND_RS06745	COG2815	serine threonine protein kinase
STND_RS06745	COG0515	serine threonine protein kinase
STND_RS06755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
STND_RS06755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
STND_RS06765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
STND_RS06780	COG0552	protein localization to endoplasmic reticulum
STND_RS06785	COG0561	phosphatase activity
STND_RS06790	COG0561	phosphatase activity
STND_RS06795	COG1725	Transcriptional regulator
STND_RS06800	COG1131	(ABC) transporter
STND_RS06810	COG4608	Belongs to the ABC transporter superfamily
STND_RS06815	COG0444	Belongs to the ABC transporter superfamily
STND_RS06820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
STND_RS06825	COG0601	transmembrane transport
STND_RS06830	COG4166	transmembrane transport
STND_RS06845	COG4166	transmembrane transport
STND_RS06855	COG2801	Transposase and inactivated derivatives
STND_RS06860	COG4608	Belongs to the ABC transporter superfamily
STND_RS06865	COG4608	Belongs to the ABC transporter superfamily
STND_RS06870	COG0084	hydrolase, TatD family'
STND_RS06875	COG2223	nitrite transmembrane transporter activity
STND_RS06880	COG2801	Transposase and inactivated derivatives
STND_RS06890	COG0280	phosphate acetyltransferase
STND_RS06895	COG0564	pseudouridine synthase activity
STND_RS06905	COG2357	RelA SpoT domain protein
STND_RS06920	COG1104	cysteine desulfurase activity
STND_RS06935	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
STND_RS06940	COG2003	Belongs to the UPF0758 family
STND_RS06985	COG1216	Glycosyl transferase, family 2
STND_RS06985	COG1442	glycosyl transferase family 8
STND_RS07000	COG0463	Glycosyl transferase, family 2
STND_RS07005	COG1216	Glycosyl transferase, family 2
STND_RS07010	COG1216	Glycosyl transferase, family 2
STND_RS07020	COG1091	dTDP-4-dehydrorhamnose reductase activity
STND_RS07030	COG0463	Glycosyl transferase, family 2
STND_RS07035	COG2151	metal-sulfur cluster biosynthetic enzyme
STND_RS07040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STND_RS07045	COG0358	DNA primase activity
STND_RS07050	COG1970	mechanosensitive ion channel activity
STND_RS07060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS07065	COG0436	Aminotransferase
STND_RS07070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS07075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS07080	COG1051	belongs to the nudix hydrolase family
STND_RS07105	COG0765	amino acid transport
STND_RS07110	COG1126	abc transporter atp-binding protein
STND_RS07125	COG1187	pseudouridine synthase activity
STND_RS07170	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
STND_RS07175	COG1518	maintenance of DNA repeat elements
STND_RS07180	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
STND_RS07185	COG0560	Phosphoserine phosphatase
STND_RS07195	COG0187	DNA topoisomerase II activity
STND_RS07205	COG1346	cytolysis
STND_RS07210	COG1380	Effector of murein hydrolase LrgA
STND_RS07220	COG1393	Belongs to the ArsC family
STND_RS07230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
STND_RS07270	COG1177	transmembrane transport
STND_RS07275	COG1176	ABC-type spermidine putrescine transport system, permease component I
STND_RS07315	COG0531	amino acid
STND_RS07320	COG0285	dihydrofolate synthase activity
STND_RS07325	COG1837	Belongs to the UPF0109 family
STND_RS07335	COG0500	methyltransferase
STND_RS07335	COG3615	Tellurite resistance protein tehB
STND_RS07345	COG0708	Exodeoxyribonuclease III
STND_RS07360	COG1597	lipid kinase activity
STND_RS07370	COG4708	membrane
STND_RS07380	COG0024	Methionine aminopeptidase
STND_RS07385	COG4109	DRTGG domain
STND_RS07395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
STND_RS07400	COG0658	competence protein
STND_RS07400	COG2333	competence protein COMEC
STND_RS07405	COG1596	polysaccharide export
STND_RS07405	COG1555	photosystem II stabilization
STND_RS07410	COG0204	Acyl-transferase
STND_RS07420	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
STND_RS07430	COG0513	Belongs to the DEAD box helicase family
STND_RS07450	COG1396	sequence-specific DNA binding
STND_RS07455	COG2211	Major facilitator Superfamily
STND_RS07470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STND_RS07485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS07490	COG1126	abc transporter atp-binding protein
STND_RS07495	COG0765	amino acid transport
STND_RS07500	COG0765	amino acid transport
STND_RS07515	COG2217	Heavy metal translocating P-type atpase
STND_RS07525	COG0159	tryptophan synthase activity
STND_RS07535	COG0135	phosphoribosylanthranilate isomerase activity
STND_RS07550	COG0512	Glutamine amidotransferase of anthranilate synthase
STND_RS07555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STND_RS07560	COG1605	Chorismate mutase
STND_RS07560	COG0287	Prephenate dehydrogenase
STND_RS07570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
STND_RS07595	COG2176	DNA-directed DNA polymerase activity
STND_RS07605	COG2151	metal-sulfur cluster biosynthetic enzyme
STND_RS07615	COG2081	HI0933 family
STND_RS07640	COG1131	(ABC) transporter
STND_RS07645	COG0537	adenosine 5'-monophosphoramidase activity
STND_RS07675	COG2226	methyltransferase
STND_RS07680	COG0799	negative regulation of ribosome biogenesis
STND_RS07685	COG1713	HD superfamily hydrolase involved in NAD metabolism
STND_RS07690	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
STND_RS07695	COG1534	Rna-binding protein
STND_RS07700	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
STND_RS07705	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
STND_RS07755	COG1335	isochorismatase
STND_RS07765	COG0436	Aminotransferase
STND_RS07770	COG0589	response to stress
STND_RS07785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
STND_RS07790	COG1253	flavin adenine dinucleotide binding
STND_RS07795	COG1119	ATPase activity
STND_RS07800	COG0025	NhaP-type Na H and K H
STND_RS07810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
STND_RS07815	COG1242	4 iron, 4 sulfur cluster binding
STND_RS07820	COG3480	Lon protease (S16) C-terminal proteolytic domain
STND_RS07825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
STND_RS07830	COG0742	ribosomal rna small subunit methyltransferase
STND_RS07835	COG0492	ferredoxin-NADP+ reductase activity
STND_RS07845	COG1126	abc transporter atp-binding protein
STND_RS07855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
STND_RS07870	COG1882	Formate acetyltransferase
STND_RS07895	COG0390	transport system, permease component
STND_RS07900	COG4619	ABC transporter
STND_RS07905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
STND_RS07920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STND_RS07955	COG2801	Transposase and inactivated derivatives
STND_RS08005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
STND_RS08010	COG2274	protein secretion by the type I secretion system
STND_RS08015	COG1132	(ABC) transporter
STND_RS08020	COG1132	(ABC) transporter
STND_RS08035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
STND_RS08040	COG4470	Protein conserved in bacteria
STND_RS08045	COG0737	Belongs to the 5'-nucleotidase family
STND_RS08050	COG0513	Belongs to the DEAD box helicase family
STND_RS08060	COG0768	penicillin binding
STND_RS08085	COG3152	Membrane
STND_RS08090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
STND_RS08105	COG4152	abc transporter atp-binding protein
STND_RS08110	COG1811	Na channel or pump
STND_RS08150	COG0561	phosphatase activity
STND_RS08155	COG0252	asparaginase activity
STND_RS08160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STND_RS08175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STND_RS08180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
STND_RS08195	COG1482	cell wall glycoprotein biosynthetic process
STND_RS08200	COG1940	carbohydrate kinase activity
STND_RS08205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
STND_RS08205	COG2190	(PTS) system
STND_RS08205	COG1263	PTS System
STND_RS08210	COG1621	beta-fructofuranosidase activity
STND_RS08215	COG1609	Transcriptional regulator
STND_RS08235	COG2131	deaminase
STND_RS08240	COG0006	proline dipeptidase activity
STND_RS08255	COG1131	(ABC) transporter
STND_RS08330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STND_RS08330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STND_RS08335	COG1193	negative regulation of DNA recombination
STND_RS08355	COG0681	Belongs to the peptidase S26 family
STND_RS08360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
STND_RS08370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
STND_RS08380	COG0456	acetyltransferase
STND_RS08385	COG1214	PFAM Peptidase M22, glycoprotease
STND_RS08405	COG0174	glutamine synthetase
STND_RS08410	COG0789	Transcriptional regulator
STND_RS08450	COG2801	Transposase and inactivated derivatives
STND_RS08485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
STND_RS08530	COG0084	hydrolase, TatD family'
STND_RS08535	COG1832	CoA-binding protein
STND_RS08540	COG3118	belongs to the thioredoxin family
STND_RS08600	COG0706	membrane insertase activity
STND_RS08665	COG0756	dUTP diphosphatase activity
STND_RS08700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STND_RS08705	COG2801	Transposase and inactivated derivatives
STND_RS08715	COG0457	Tetratricopeptide repeat
STND_RS08715	COG0705	Rhomboid family
STND_RS08720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STND_RS08740	COG2226	methyltransferase
STND_RS08765	COG0425	Belongs to the sulfur carrier protein TusA family
STND_RS08770	COG2391	methyltransferase activity
STND_RS08775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STND_RS08780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
STND_RS08790	COG1363	Peptidase, m42
STND_RS08795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
STND_RS08800	COG1266	CAAX protease self-immunity
STND_RS08860	COG1459	type II secretion system
STND_RS08865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
STND_RS08900	COG0440	acetolactate synthase activity
STND_RS08905	COG0028	Belongs to the TPP enzyme family
STND_RS08910	COG0129	dihydroxy-acid dehydratase activity
STND_RS08915	COG1461	Dihydroxyacetone kinase
STND_RS08925	COG0534	Mate efflux family protein
STND_RS08950	COG1454	alcohol dehydrogenase
STND_RS08950	COG1012	belongs to the aldehyde dehydrogenase family
STND_RS08955	COG1012	belongs to the aldehyde dehydrogenase family
STND_RS08955	COG1454	alcohol dehydrogenase
STND_RS08960	COG1454	alcohol dehydrogenase
STND_RS08960	COG1012	belongs to the aldehyde dehydrogenase family
STND_RS08965	COG3590	peptidase
STND_RS08970	COG0366	Alpha amylase catalytic
STND_RS08975	COG0366	Alpha amylase catalytic
STND_RS08980	COG0366	Alpha amylase catalytic
STND_RS08990	COG1609	Transcriptional regulator
STND_RS08995	COG2188	Transcriptional regulator
STND_RS09000	COG4475	Protein of unknown function (DUF436)
STND_RS09025	COG1301	dicarboxylic acid transport
STND_RS09095	COG0191	fructose-bisphosphate aldolase activity
STND_RS09155	COG0201	protein transport
STND_RS09295	COG1396	sequence-specific DNA binding
STND_RS09305	COG1132	(ABC) transporter
STND_RS09340	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
STND_RS09380	COG0602	queuosine metabolic process
STND_RS09390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STND_RS09415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
STND_RS09425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STND_RS09450	COG2261	transglycosylase associated protein
STND_RS09470	COG3237	CsbD-like
STND_RS09495	COG1511	domain protein
STND_RS09495	COG1511	domain protein
STND_RS09505	COG3759	membrane
STND_RS09520	COG0305	Participates in initiation and elongation during chromosome replication
STND_RS09540	COG0494	nUDIX hydrolase
STND_RS09555	COG0741	lytic transglycosylase activity
STND_RS09560	COG1388	LysM domain
STND_RS09560	COG3584	3D domain protein
STND_RS09565	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
STND_RS09580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
STND_RS09620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
STND_RS09625	COG0488	(ABC) transporter
STND_RS09660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STND_RS09665	COG1475	DNA binding
STND_RS09675	COG0588	phosphoglycerate mutase activity
STND_RS09705	COG1442	glycosyl transferase family 8
STND_RS09730	COG4166	transmembrane transport
STND_RS09735	COG4166	transmembrane transport