locus-tag	class	description
BBD27_RS00005	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBD27_RS00005	COG3942	CHAP domain
BBD27_RS00025	COG3443	Belongs to the bacterial solute-binding protein 9 family
BBD27_RS00025	COG0803	Belongs to the bacterial solute-binding protein 9 family
BBD27_RS00050	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BBD27_RS00080	COG2801	Transposase and inactivated derivatives
BBD27_RS00090	COG1278	Cold shock
BBD27_RS00135	COG0720	synthase
BBD27_RS00145	COG0251	oxidation-reduction process
BBD27_RS00175	COG0436	Aminotransferase
BBD27_RS00185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BBD27_RS00185	COG1199	ATP-dependent helicase activity
BBD27_RS00195	COG1079	Belongs to the binding-protein-dependent transport system permease family
BBD27_RS00200	COG4603	Belongs to the binding-protein-dependent transport system permease family
BBD27_RS00205	COG3845	ABC transporter
BBD27_RS00210	COG1744	ABC transporter substrate-binding protein PnrA-like
BBD27_RS00215	COG0295	cytidine deaminase activity
BBD27_RS00235	COG2813	Specifically methylates the guanine in position
BBD27_RS00255	COG2801	Transposase and inactivated derivatives
BBD27_RS00270	COG0038	chloride channel
BBD27_RS00290	COG2801	Transposase and inactivated derivatives
BBD27_RS00300	COG5002	protein histidine kinase activity
BBD27_RS00305	COG5002	protein histidine kinase activity
BBD27_RS00330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBD27_RS00335	COG4684	Psort location CytoplasmicMembrane, score
BBD27_RS00340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBD27_RS00360	COG0582	viral genome integration into host DNA
BBD27_RS00365	COG1396	sequence-specific DNA binding
BBD27_RS00415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBD27_RS00420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBD27_RS00445	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BBD27_RS00455	COG1696	Membrane protein involved in D-alanine export
BBD27_RS00470	COG1132	(ABC) transporter
BBD27_RS00500	COG2890	protein-(glutamine-N5) methyltransferase activity
BBD27_RS00510	COG1435	thymidine kinase activity
BBD27_RS00520	COG0625	glutathione transferase activity
BBD27_RS00525	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BBD27_RS00560	COG3599	regulation of cell shape
BBD27_RS00580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBD27_RS00590	COG0849	cell division
BBD27_RS00615	COG1217	gtp-binding protein TYPA
BBD27_RS00620	COG1940	carbohydrate kinase activity
BBD27_RS00625	COG4483	Protein conserved in bacteria
BBD27_RS00630	COG0735	belongs to the Fur family
BBD27_RS00635	COG0783	Belongs to the Dps family
BBD27_RS00640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BBD27_RS00650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BBD27_RS00680	COG1704	LemA family
BBD27_RS00730	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBD27_RS00765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBD27_RS00770	COG0406	alpha-ribazole phosphatase activity
BBD27_RS00790	COG1388	LysM domain
BBD27_RS00790	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBD27_RS00800	COG3328	transposase activity
BBD27_RS00810	COG0494	nUDIX hydrolase
BBD27_RS00820	COG1914	H( )-stimulated, divalent metal cation uptake system
BBD27_RS00830	COG4443	Transcriptional Coactivator p15 (PC4)
BBD27_RS00840	COG1268	BioY protein
BBD27_RS00850	COG0826	peptidase U32
BBD27_RS00895	COG2183	response to ionizing radiation
BBD27_RS00900	COG0701	Predicted permease
BBD27_RS00905	COG3689	TIGRFAM TIGR03943 family protein
BBD27_RS00915	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBD27_RS00920	COG1518	maintenance of DNA repeat elements
BBD27_RS00980	COG2963	transposase activity
BBD27_RS01040	COG0077	Prephenate dehydratase
BBD27_RS01065	COG0287	Prephenate dehydrogenase
BBD27_RS01090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BBD27_RS01095	COG1368	sulfuric ester hydrolase activity
BBD27_RS01125	COG1609	Transcriptional regulator
BBD27_RS01130	COG0006	proline dipeptidase activity
BBD27_RS01135	COG1185	polyribonucleotide nucleotidyltransferase activity
BBD27_RS01150	COG0557	exoribonuclease II activity
BBD27_RS01165	COG0237	dephospho-CoA kinase activity
BBD27_RS01170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BBD27_RS01175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBD27_RS01180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BBD27_RS01190	COG3711	transcriptional antiterminator
BBD27_RS01200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BBD27_RS01205	COG0768	penicillin binding
BBD27_RS01210	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BBD27_RS01255	COG0765	amino acid transport
BBD27_RS01260	COG4703	Protein of unknown function (DUF1797)
BBD27_RS01265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBD27_RS01270	COG0542	response to heat
BBD27_RS01275	COG0494	nUDIX hydrolase
BBD27_RS01290	COG0673	inositol 2-dehydrogenase activity
BBD27_RS01320	COG0539	negative regulation of cytoplasmic translation
BBD27_RS01340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBD27_RS01350	COG0187	DNA topoisomerase II activity
BBD27_RS01370	COG2040	homocysteine
BBD27_RS01375	COG0833	amino acid
BBD27_RS01390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBD27_RS01400	COG3425	synthase
BBD27_RS01415	COG1272	protein, Hemolysin III
BBD27_RS01445	COG0438	transferase activity, transferring glycosyl groups
BBD27_RS01510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBD27_RS01515	COG0686	Belongs to the AlaDH PNT family
BBD27_RS01520	COG0686	Belongs to the AlaDH PNT family
BBD27_RS01525	COG1473	amidohydrolase
BBD27_RS01530	COG1187	pseudouridine synthase activity
BBD27_RS01565	COG1131	(ABC) transporter
BBD27_RS01575	COG3279	Response regulator of the LytR AlgR family
BBD27_RS01640	COG2801	Transposase and inactivated derivatives
BBD27_RS01645	COG0577	efflux transmembrane transporter activity
BBD27_RS01680	COG0577	efflux transmembrane transporter activity
BBD27_RS01685	COG0577	efflux transmembrane transporter activity
BBD27_RS01720	COG0505	Belongs to the CarA family
BBD27_RS01740	COG0564	pseudouridine synthase activity
BBD27_RS01750	COG0583	DNA-binding transcription factor activity
BBD27_RS01780	COG2801	Transposase and inactivated derivatives
BBD27_RS01795	COG1263	PTS System
BBD27_RS01795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBD27_RS01795	COG2190	(PTS) system
BBD27_RS01805	COG1113	amino acid transport
BBD27_RS01865	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBD27_RS01865	COG1388	LysM domain
BBD27_RS01870	COG0347	Belongs to the P(II) protein family
BBD27_RS01875	COG0004	ammonium transporteR
BBD27_RS01885	COG4467	Involved in initiation control of chromosome replication
BBD27_RS01890	COG1774	PSP1 C-terminal conserved region
BBD27_RS01895	COG0470	DNA polymerase III
BBD27_RS01915	COG0772	Belongs to the SEDS family
BBD27_RS01950	COG0356	it plays a direct role in the translocation of protons across the membrane
BBD27_RS01990	COG2962	Rard protein
BBD27_RS02005	COG0726	polysaccharide deacetylase
BBD27_RS02010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBD27_RS02015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BBD27_RS02030	COG0436	Aminotransferase
BBD27_RS02035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBD27_RS02065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBD27_RS02070	COG4122	O-methyltransferase activity
BBD27_RS02095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBD27_RS02095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBD27_RS02115	COG1702	phosphate starvation-inducible protein PhoH
BBD27_RS02175	COG0242	peptide deformylase activity
BBD27_RS02180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBD27_RS02200	COG0488	(ABC) transporter
BBD27_RS02265	COG1104	cysteine desulfurase activity
BBD27_RS02275	COG0285	dihydrofolate synthase activity
BBD27_RS02280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBD27_RS02290	COG1105	Belongs to the carbohydrate kinase PfkB family
BBD27_RS02295	COG1349	DNA-binding transcription factor activity
BBD27_RS02330	COG0439	Biotin carboxylase
BBD27_RS02345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBD27_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
BBD27_RS02355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBD27_RS02375	COG1846	Transcriptional regulator
BBD27_RS02380	COG1024	Enoyl-CoA hydratase
BBD27_RS02385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBD27_RS02390	COG0527	aspartate kinase activity
BBD27_RS02480	COG1040	competence protein
BBD27_RS02485	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BBD27_RS02490	COG1739	Uncharacterized protein family UPF0029
BBD27_RS02505	COG0517	IMP dehydrogenase activity
BBD27_RS02525	COG0559	Belongs to the binding-protein-dependent transport system permease family
BBD27_RS02535	COG4471	UPF0298 protein
BBD27_RS02565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BBD27_RS02570	COG0626	cystathionine gamma-synthase activity
BBD27_RS02575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBD27_RS02580	COG2244	polysaccharide biosynthetic process
BBD27_RS02600	COG1611	Belongs to the LOG family
BBD27_RS02620	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BBD27_RS02625	COG0195	Participates in both transcription termination and antitermination
BBD27_RS02635	COG1316	TRANSCRIPTIONal
BBD27_RS02640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBD27_RS02645	COG0802	atpase or kinase
BBD27_RS02650	COG2252	PERMEase
BBD27_RS02655	COG0561	phosphatase activity
BBD27_RS02660	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BBD27_RS02670	COG3715	PTS system
BBD27_RS02675	COG3716	PTS system mannose fructose sorbose family IID component
BBD27_RS02715	COG1484	DNA-dependent DNA replication
BBD27_RS02730	COG5002	protein histidine kinase activity
BBD27_RS02735	COG0745	RESPONSE REGULATOR receiver
BBD27_RS02750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBD27_RS02760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BBD27_RS02770	COG1122	ATPase activity
BBD27_RS02795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBD27_RS02805	COG1464	Belongs to the NlpA lipoprotein family
BBD27_RS02810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBD27_RS02830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BBD27_RS02835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBD27_RS02840	COG1122	ATPase activity
BBD27_RS02850	COG0310	cobalt ion transport
BBD27_RS02855	COG0829	nickel cation binding
BBD27_RS02905	COG2274	protein secretion by the type I secretion system
BBD27_RS02910	COG2274	protein secretion by the type I secretion system
BBD27_RS02915	COG2274	protein secretion by the type I secretion system
BBD27_RS02935	COG0671	phosphoesterase, PA-phosphatase related
BBD27_RS02940	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BBD27_RS02950	COG0569	domain protein
BBD27_RS02955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBD27_RS02965	COG1187	pseudouridine synthase activity
BBD27_RS02970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBD27_RS02975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBD27_RS02995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BBD27_RS03040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBD27_RS03045	COG1254	Belongs to the acylphosphatase family
BBD27_RS03070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BBD27_RS03090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBD27_RS03100	COG0116	Belongs to the methyltransferase superfamily
BBD27_RS03125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBD27_RS03130	COG3579	cysteine-type endopeptidase activity
BBD27_RS03145	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BBD27_RS03170	COG1349	DNA-binding transcription factor activity
BBD27_RS03195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBD27_RS03200	COG0564	pseudouridine synthase activity
BBD27_RS03235	COG1116	anion transmembrane transporter activity
BBD27_RS03235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBD27_RS03240	COG4120	Belongs to the binding-protein-dependent transport system permease family
BBD27_RS03255	COG4589	Belongs to the CDS family
BBD27_RS03285	COG2190	(PTS) system
BBD27_RS03285	COG1263	PTS System
BBD27_RS03285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBD27_RS03290	COG1263	PTS System
BBD27_RS03290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBD27_RS03290	COG2190	(PTS) system
BBD27_RS03295	COG1263	PTS System
BBD27_RS03295	COG2190	(PTS) system
BBD27_RS03295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBD27_RS03305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBD27_RS03310	COG1121	(ABC) transporter
BBD27_RS03325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBD27_RS03345	COG0444	Belongs to the ABC transporter superfamily
BBD27_RS03350	COG0444	Belongs to the ABC transporter superfamily
BBD27_RS03355	COG0444	Belongs to the ABC transporter superfamily
BBD27_RS03360	COG0444	Belongs to the ABC transporter superfamily
BBD27_RS03375	COG0601	transmembrane transport
BBD27_RS03385	COG0719	Fe-S assembly protein
BBD27_RS03395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBD27_RS03400	COG0719	Fe-S assembly protein
BBD27_RS03410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBD27_RS03425	COG0765	amino acid transport
BBD27_RS03430	COG1126	abc transporter atp-binding protein
BBD27_RS03460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBD27_RS03495	COG0737	Belongs to the 5'-nucleotidase family
BBD27_RS03500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBD27_RS03510	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BBD27_RS03520	COG0504	CTP synthase activity
BBD27_RS03535	COG0668	transmembrane transport
BBD27_RS03550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBD27_RS03555	COG1473	amidohydrolase
BBD27_RS03590	COG4720	Psort location CytoplasmicMembrane, score
BBD27_RS03595	COG0351	phosphomethylpyrimidine kinase
BBD27_RS03630	COG1876	peptidase activity
BBD27_RS03645	COG3830	Belongs to the UPF0237 family
BBD27_RS03660	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBD27_RS03660	COG3942	CHAP domain
BBD27_RS03720	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBD27_RS03745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBD27_RS03760	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BBD27_RS03770	COG1045	serine acetyltransferase
BBD27_RS03785	COG1686	Belongs to the peptidase S11 family
BBD27_RS03795	COG0542	response to heat
BBD27_RS03800	COG4463	regulation of RNA biosynthetic process
BBD27_RS03825	COG1619	proteins homologs of microcin C7 resistance protein MccF
BBD27_RS03845	COG2801	Transposase and inactivated derivatives
BBD27_RS03865	COG2309	aminopeptidase activity
BBD27_RS03955	COG1393	Belongs to the ArsC family
BBD27_RS03970	COG2818	Glycosylase
BBD27_RS04010	COG4550	Control of competence regulator ComK, YlbF/YmcA
BBD27_RS04025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBD27_RS04045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBD27_RS04050	COG0151	Belongs to the GarS family
BBD27_RS04055	COG3942	CHAP domain
BBD27_RS04055	COG1388	LysM domain
BBD27_RS04075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBD27_RS04090	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBD27_RS04100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBD27_RS04115	COG0436	Aminotransferase
BBD27_RS04130	COG3942	CHAP domain
BBD27_RS04250	COG2801	Transposase and inactivated derivatives
BBD27_RS04270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBD27_RS04300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BBD27_RS04305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBD27_RS04325	COG0592	DNA-directed DNA polymerase activity
BBD27_RS04335	COG1475	DNA binding
BBD27_RS04340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBD27_RS04375	COG0488	(ABC) transporter
BBD27_RS04380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBD27_RS04410	COG0612	Peptidase, M16
BBD27_RS04420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBD27_RS04435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBD27_RS04440	COG1388	LysM domain
BBD27_RS04440	COG3584	3D domain protein
BBD27_RS04445	COG0741	lytic transglycosylase activity
BBD27_RS04460	COG0494	nUDIX hydrolase
BBD27_RS04480	COG0305	Participates in initiation and elongation during chromosome replication
BBD27_RS04495	COG3759	membrane
BBD27_RS04505	COG1511	domain protein
BBD27_RS04505	COG1511	domain protein
BBD27_RS04525	COG3328	transposase activity
BBD27_RS04535	COG3237	CsbD-like
BBD27_RS04555	COG2261	transglycosylase associated protein
BBD27_RS04580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BBD27_RS04590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BBD27_RS04620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBD27_RS04630	COG0602	queuosine metabolic process
BBD27_RS04670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BBD27_RS04710	COG1132	(ABC) transporter
BBD27_RS04720	COG1396	sequence-specific DNA binding
BBD27_RS04725	COG1132	(ABC) transporter
BBD27_RS04730	COG0515	serine threonine protein kinase
BBD27_RS04745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BBD27_RS04890	COG0201	protein transport
BBD27_RS04950	COG0191	fructose-bisphosphate aldolase activity
BBD27_RS04955	COG0582	viral genome integration into host DNA
BBD27_RS04960	COG3328	transposase activity
BBD27_RS04985	COG2217	Heavy metal translocating P-type atpase
BBD27_RS04990	COG0640	Transcriptional regulator
BBD27_RS05025	COG4475	Protein of unknown function (DUF436)
BBD27_RS05030	COG2188	Transcriptional regulator
BBD27_RS05035	COG1609	Transcriptional regulator
BBD27_RS05045	COG0366	Alpha amylase catalytic
BBD27_RS05050	COG0366	Alpha amylase catalytic
BBD27_RS05055	COG0366	Alpha amylase catalytic
BBD27_RS05060	COG3590	peptidase
BBD27_RS05065	COG1454	alcohol dehydrogenase
BBD27_RS05065	COG1012	belongs to the aldehyde dehydrogenase family
BBD27_RS05070	COG1012	belongs to the aldehyde dehydrogenase family
BBD27_RS05070	COG1454	alcohol dehydrogenase
BBD27_RS05075	COG1012	belongs to the aldehyde dehydrogenase family
BBD27_RS05075	COG1454	alcohol dehydrogenase
BBD27_RS05100	COG0534	Mate efflux family protein
BBD27_RS05110	COG1461	Dihydroxyacetone kinase
BBD27_RS05115	COG0129	dihydroxy-acid dehydratase activity
BBD27_RS05120	COG0028	Belongs to the TPP enzyme family
BBD27_RS05125	COG0440	acetolactate synthase activity
BBD27_RS05160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBD27_RS05165	COG1459	type II secretion system
BBD27_RS05225	COG1266	CAAX protease self-immunity
BBD27_RS05230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBD27_RS05235	COG1363	Peptidase, m42
BBD27_RS05245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBD27_RS05250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBD27_RS05255	COG2391	methyltransferase activity
BBD27_RS05260	COG0425	Belongs to the sulfur carrier protein TusA family
BBD27_RS05290	COG2226	methyltransferase
BBD27_RS05310	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBD27_RS05315	COG0457	Tetratricopeptide repeat
BBD27_RS05315	COG0705	Rhomboid family
BBD27_RS05320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BBD27_RS05355	COG0756	dUTP diphosphatase activity
BBD27_RS05395	COG4166	transmembrane transport
BBD27_RS05400	COG4166	transmembrane transport
BBD27_RS05425	COG0706	membrane insertase activity
BBD27_RS05490	COG3118	belongs to the thioredoxin family
BBD27_RS05495	COG1832	CoA-binding protein
BBD27_RS05500	COG0084	hydrolase, TatD family'
BBD27_RS05545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBD27_RS05575	COG2801	Transposase and inactivated derivatives
BBD27_RS05615	COG0789	Transcriptional regulator
BBD27_RS05620	COG0174	glutamine synthetase
BBD27_RS05640	COG1214	PFAM Peptidase M22, glycoprotease
BBD27_RS05645	COG0456	acetyltransferase
BBD27_RS05665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BBD27_RS05670	COG0681	Belongs to the peptidase S26 family
BBD27_RS05695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBD27_RS05695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBD27_RS05770	COG1131	(ABC) transporter
BBD27_RS05785	COG0006	proline dipeptidase activity
BBD27_RS05790	COG2131	deaminase
BBD27_RS05810	COG1609	Transcriptional regulator
BBD27_RS05815	COG1621	beta-fructofuranosidase activity
BBD27_RS05820	COG1263	PTS System
BBD27_RS05820	COG2190	(PTS) system
BBD27_RS05820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBD27_RS05825	COG1940	carbohydrate kinase activity
BBD27_RS05830	COG1482	cell wall glycoprotein biosynthetic process
BBD27_RS05845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBD27_RS05850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBD27_RS05860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBD27_RS05865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBD27_RS05870	COG0252	asparaginase activity
BBD27_RS05875	COG0561	phosphatase activity
BBD27_RS05915	COG1811	Na channel or pump
BBD27_RS05920	COG4152	abc transporter atp-binding protein
BBD27_RS05935	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BBD27_RS05945	COG3152	Membrane
BBD27_RS05980	COG0768	penicillin binding
BBD27_RS05990	COG0513	Belongs to the DEAD box helicase family
BBD27_RS05995	COG0737	Belongs to the 5'-nucleotidase family
BBD27_RS06000	COG4470	Protein conserved in bacteria
BBD27_RS06005	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BBD27_RS06020	COG1132	(ABC) transporter
BBD27_RS06025	COG1132	(ABC) transporter
BBD27_RS06035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBD27_RS06085	COG2801	Transposase and inactivated derivatives
BBD27_RS06120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBD27_RS06135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BBD27_RS06140	COG4619	ABC transporter
BBD27_RS06145	COG0390	transport system, permease component
BBD27_RS06175	COG1882	Formate acetyltransferase
BBD27_RS06190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBD27_RS06200	COG1126	abc transporter atp-binding protein
BBD27_RS06210	COG0492	ferredoxin-NADP+ reductase activity
BBD27_RS06215	COG0742	ribosomal rna small subunit methyltransferase
BBD27_RS06220	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBD27_RS06225	COG3480	Lon protease (S16) C-terminal proteolytic domain
BBD27_RS06230	COG1242	4 iron, 4 sulfur cluster binding
BBD27_RS06235	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BBD27_RS06245	COG0025	NhaP-type Na H and K H
BBD27_RS06250	COG1119	ATPase activity
BBD27_RS06255	COG1253	flavin adenine dinucleotide binding
BBD27_RS06260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBD27_RS06275	COG0589	response to stress
BBD27_RS06280	COG0436	Aminotransferase
BBD27_RS06290	COG1335	isochorismatase
BBD27_RS06305	COG2723	6-phospho-beta-galactosidase activity
BBD27_RS06340	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BBD27_RS06345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BBD27_RS06350	COG1534	Rna-binding protein
BBD27_RS06355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBD27_RS06360	COG1713	HD superfamily hydrolase involved in NAD metabolism
BBD27_RS06365	COG0799	negative regulation of ribosome biogenesis
BBD27_RS06370	COG2226	methyltransferase
BBD27_RS06400	COG0537	adenosine 5'-monophosphoramidase activity
BBD27_RS06405	COG1131	(ABC) transporter
BBD27_RS06430	COG2081	HI0933 family
BBD27_RS06440	COG2151	metal-sulfur cluster biosynthetic enzyme
BBD27_RS06450	COG2176	DNA-directed DNA polymerase activity
BBD27_RS06475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBD27_RS06485	COG0287	Prephenate dehydrogenase
BBD27_RS06485	COG1605	Chorismate mutase
BBD27_RS06490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBD27_RS06495	COG0512	Glutamine amidotransferase of anthranilate synthase
BBD27_RS06510	COG0135	phosphoribosylanthranilate isomerase activity
BBD27_RS06520	COG0159	tryptophan synthase activity
BBD27_RS06530	COG2217	Heavy metal translocating P-type atpase
BBD27_RS06545	COG0765	amino acid transport
BBD27_RS06550	COG0765	amino acid transport
BBD27_RS06555	COG1126	abc transporter atp-binding protein
BBD27_RS06560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBD27_RS06580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBD27_RS06595	COG2211	Major facilitator Superfamily
BBD27_RS06600	COG1396	sequence-specific DNA binding
BBD27_RS06620	COG0513	Belongs to the DEAD box helicase family
BBD27_RS06630	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BBD27_RS06635	COG0726	polysaccharide deacetylase
BBD27_RS06640	COG0204	Acyl-transferase
BBD27_RS06645	COG1555	photosystem II stabilization
BBD27_RS06645	COG1596	polysaccharide export
BBD27_RS06650	COG0658	competence protein
BBD27_RS06650	COG2333	competence protein COMEC
BBD27_RS06655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBD27_RS06665	COG4109	DRTGG domain
BBD27_RS06670	COG0024	Methionine aminopeptidase
BBD27_RS06680	COG4708	membrane
BBD27_RS06690	COG1597	lipid kinase activity
BBD27_RS06705	COG0708	Exodeoxyribonuclease III
BBD27_RS06710	COG0500	methyltransferase
BBD27_RS06710	COG3615	Tellurite resistance protein tehB
BBD27_RS06720	COG1837	Belongs to the UPF0109 family
BBD27_RS06725	COG0285	dihydrofolate synthase activity
BBD27_RS06730	COG0531	amino acid
BBD27_RS06770	COG1176	ABC-type spermidine putrescine transport system, permease component I
BBD27_RS06775	COG1177	transmembrane transport
BBD27_RS06815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBD27_RS06825	COG1393	Belongs to the ArsC family
BBD27_RS06835	COG1380	Effector of murein hydrolase LrgA
BBD27_RS06840	COG1346	cytolysis
BBD27_RS06850	COG0187	DNA topoisomerase II activity
BBD27_RS06860	COG0560	Phosphoserine phosphatase
BBD27_RS06865	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BBD27_RS06870	COG1518	maintenance of DNA repeat elements
BBD27_RS06875	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBD27_RS06920	COG1187	pseudouridine synthase activity
BBD27_RS06940	COG1126	abc transporter atp-binding protein
BBD27_RS06945	COG0765	amino acid transport
BBD27_RS06970	COG1051	belongs to the nudix hydrolase family
BBD27_RS06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBD27_RS06980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBD27_RS06985	COG0436	Aminotransferase
BBD27_RS06990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBD27_RS07000	COG1970	mechanosensitive ion channel activity
BBD27_RS07005	COG0358	DNA primase activity
BBD27_RS07010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBD27_RS07015	COG2151	metal-sulfur cluster biosynthetic enzyme
BBD27_RS07020	COG0463	Glycosyl transferase, family 2
BBD27_RS07030	COG1091	dTDP-4-dehydrorhamnose reductase activity
BBD27_RS07050	COG1442	glycosyl transferase family 8
BBD27_RS07050	COG1216	Glycosyl transferase, family 2
BBD27_RS07065	COG1215	transferase activity, transferring glycosyl groups
BBD27_RS07090	COG2003	Belongs to the UPF0758 family
BBD27_RS07095	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BBD27_RS07110	COG1104	cysteine desulfurase activity
BBD27_RS07125	COG2357	RelA SpoT domain protein
BBD27_RS07135	COG0564	pseudouridine synthase activity
BBD27_RS07140	COG0280	phosphate acetyltransferase
BBD27_RS07150	COG2801	Transposase and inactivated derivatives
BBD27_RS07155	COG2223	nitrite transmembrane transporter activity
BBD27_RS07160	COG0084	hydrolase, TatD family'
BBD27_RS07165	COG4608	Belongs to the ABC transporter superfamily
BBD27_RS07170	COG2801	Transposase and inactivated derivatives
BBD27_RS07180	COG4166	transmembrane transport
BBD27_RS07190	COG4166	transmembrane transport
BBD27_RS07195	COG0601	transmembrane transport
BBD27_RS07200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBD27_RS07205	COG0444	Belongs to the ABC transporter superfamily
BBD27_RS07210	COG4608	Belongs to the ABC transporter superfamily
BBD27_RS07220	COG1131	(ABC) transporter
BBD27_RS07225	COG1725	Transcriptional regulator
BBD27_RS07230	COG0561	phosphatase activity
BBD27_RS07235	COG0561	phosphatase activity
BBD27_RS07240	COG0552	protein localization to endoplasmic reticulum
BBD27_RS07255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBD27_RS07265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBD27_RS07265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBD27_RS07275	COG2815	serine threonine protein kinase
BBD27_RS07275	COG0515	serine threonine protein kinase
BBD27_RS07285	COG4585	Histidine kinase
BBD27_RS07290	COG2197	response regulator
BBD27_RS07340	COG0488	(ABC) transporter
BBD27_RS07345	COG3064	Membrane
BBD27_RS07355	COG1609	Transcriptional regulator
BBD27_RS07370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBD27_RS07375	COG2017	converts alpha-aldose to the beta-anomer
BBD27_RS07380	COG2190	(PTS) system
BBD27_RS07380	COG2211	Major facilitator Superfamily
BBD27_RS07385	COG3250	beta-galactosidase activity
BBD27_RS07390	COG0420	3'-5' exonuclease activity
BBD27_RS07395	COG0419	ATPase involved in DNA repair
BBD27_RS07410	COG2801	Transposase and inactivated derivatives
BBD27_RS07415	COG1396	sequence-specific DNA binding
BBD27_RS07460	COG0577	efflux transmembrane transporter activity
BBD27_RS07465	COG1216	Glycosyl transferase, family 2
BBD27_RS07465	COG1442	glycosyl transferase family 8
BBD27_RS07475	COG1280	lysine exporter protein (LysE YggA)
BBD27_RS07500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBD27_RS07535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBD27_RS07540	COG0656	L-ascorbic acid biosynthetic process
BBD27_RS07550	COG0778	Nitroreductase
BBD27_RS07555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBD27_RS07565	COG1959	2 iron, 2 sulfur cluster binding
BBD27_RS07570	COG2514	catechol 2,3-dioxygenase activity
BBD27_RS07580	COG0531	amino acid
BBD27_RS07590	COG1482	cell wall glycoprotein biosynthetic process
BBD27_RS07595	COG1482	cell wall glycoprotein biosynthetic process
BBD27_RS07605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBD27_RS07605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBD27_RS07610	COG0534	Mate efflux family protein
BBD27_RS07615	COG2233	PERMEase
BBD27_RS07620	COG2233	PERMEase
BBD27_RS07630	COG0745	RESPONSE REGULATOR receiver
BBD27_RS07635	COG0784	Response regulator, receiver
BBD27_RS07635	COG2198	Histidine kinase
BBD27_RS07635	COG5002	protein histidine kinase activity
BBD27_RS07640	COG1136	(ABC) transporter
BBD27_RS07645	COG0577	efflux transmembrane transporter activity
BBD27_RS07665	COG1131	(ABC) transporter
BBD27_RS07715	COG1131	(ABC) transporter
BBD27_RS07725	COG4585	Histidine kinase
BBD27_RS07730	COG2197	response regulator
BBD27_RS07740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBD27_RS07765	COG1760	l-serine dehydratase
BBD27_RS07770	COG1011	Hydrolase
BBD27_RS07780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBD27_RS07805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBD27_RS07820	COG1196	nuclear chromosome segregation
BBD27_RS07855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBD27_RS07855	COG1328	CTP reductase activity
BBD27_RS07860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBD27_RS07890	COG0488	(ABC) transporter
BBD27_RS07910	COG3764	Sortase (surface protein transpeptidase)
BBD27_RS07940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBD27_RS07945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBD27_RS07950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BBD27_RS07955	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BBD27_RS07960	COG0372	Belongs to the citrate synthase family
BBD27_RS07995	COG0513	Belongs to the DEAD box helicase family
BBD27_RS08005	COG0488	(ABC) transporter
BBD27_RS08015	COG0392	lysyltransferase activity
BBD27_RS08015	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BBD27_RS08020	COG3442	glutamine amidotransferase
BBD27_RS08025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBD27_RS08050	COG2384	SAM-dependent methyltransferase
BBD27_RS08065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBD27_RS08070	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BBD27_RS08080	COG1088	dTDP-glucose 4,6-dehydratase activity
BBD27_RS08110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBD27_RS08120	COG0647	UMP catabolic process
BBD27_RS08175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBD27_RS08185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BBD27_RS08195	COG0107	imidazoleglycerol-phosphate synthase activity
BBD27_RS08210	COG0772	Belongs to the SEDS family
BBD27_RS08220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBD27_RS08235	COG0300	oxidoreductase activity
BBD27_RS08240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBD27_RS08240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBD27_RS08260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBD27_RS08285	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BBD27_RS08290	COG1438	arginine binding
BBD27_RS08295	COG0497	DNA recombination
BBD27_RS08300	COG1307	EDD domain protein, DegV family
BBD27_RS08305	COG2755	lipolytic protein G-D-S-L family
BBD27_RS08315	COG0776	regulation of translation
BBD27_RS08325	COG0167	dihydroorotate dehydrogenase activity
BBD27_RS08375	COG0469	pyruvate kinase activity
BBD27_RS08450	COG0716	FMN binding
BBD27_RS08455	COG0038	chloride channel
BBD27_RS08465	COG0038	chloride channel
BBD27_RS08470	COG0335	large ribosomal subunit rRNA binding
BBD27_RS08490	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBD27_RS08495	COG1956	GAF domain-containing protein
BBD27_RS08500	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBD27_RS08510	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BBD27_RS08510	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BBD27_RS08515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BBD27_RS08525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBD27_RS08550	COG0765	amino acid transport
BBD27_RS08555	COG0765	amino acid transport
BBD27_RS08560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBD27_RS08565	COG1126	abc transporter atp-binding protein
BBD27_RS08570	COG0745	RESPONSE REGULATOR receiver
BBD27_RS08575	COG5002	protein histidine kinase activity
BBD27_RS08580	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BBD27_RS08590	COG2348	transferase activity, transferring amino-acyl groups
BBD27_RS08625	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BBD27_RS08630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBD27_RS08635	COG2884	Cell division ATP-binding protein ftsE
BBD27_RS08640	COG2177	Part of the ABC transporter FtsEX involved in
BBD27_RS08645	COG1051	belongs to the nudix hydrolase family
BBD27_RS08650	COG0628	permease
BBD27_RS08660	COG0681	Belongs to the peptidase S26 family
BBD27_RS08720	COG1573	uracil-dna glycosylase
BBD27_RS08740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BBD27_RS08750	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BBD27_RS08770	COG3328	transposase activity
BBD27_RS08775	COG1316	TRANSCRIPTIONal
BBD27_RS08820	COG1216	Glycosyl transferase, family 2
BBD27_RS08820	COG1442	glycosyl transferase family 8
BBD27_RS08830	COG1216	Glycosyl transferase, family 2
BBD27_RS08830	COG1442	glycosyl transferase family 8
BBD27_RS08835	COG2244	polysaccharide biosynthetic process
BBD27_RS08845	COG0562	UDP-galactopyranose mutase
BBD27_RS08870	COG0628	permease
BBD27_RS08900	COG4667	esterase of the alpha-beta hydrolase superfamily
BBD27_RS08910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBD27_RS08945	COG1857	crispr-associated protein
BBD27_RS08960	COG1518	maintenance of DNA repeat elements
BBD27_RS08980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BBD27_RS08985	COG0022	dehydrogenase e1 component
BBD27_RS08985	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBD27_RS08990	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBD27_RS09020	COG1523	belongs to the glycosyl hydrolase 13 family
BBD27_RS09030	COG1523	belongs to the glycosyl hydrolase 13 family
BBD27_RS09040	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBD27_RS09045	COG4605	iron ion homeostasis
BBD27_RS09050	COG4604	ABC transporter, ATP-binding protein
BBD27_RS09055	COG4607	ABC-type enterochelin transport system periplasmic component
BBD27_RS09060	COG2822	iron ion transport
BBD27_RS09065	COG2837	iron assimilation
BBD27_RS09070	COG0672	)-iron permease
BBD27_RS09075	COG0805	protein transport
BBD27_RS09080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBD27_RS09095	COG1640	4-alpha-glucanotransferase
BBD27_RS09100	COG0058	SHG alpha-glucan phosphorylase activity
BBD27_RS09115	COG0095	Lipoate-protein ligase
BBD27_RS09130	COG0704	Plays a role in the regulation of phosphate uptake
BBD27_RS09145	COG0581	inorganic phosphate transmembrane transporter activity
BBD27_RS09150	COG0573	inorganic phosphate transmembrane transporter activity
BBD27_RS09160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBD27_RS09160	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BBD27_RS09165	COG0483	inositol monophosphate 1-phosphatase activity
BBD27_RS09175	COG1393	Belongs to the ArsC family
BBD27_RS09180	COG0196	riboflavin kinase activity
BBD27_RS09185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BBD27_RS09215	COG2873	o-acetylhomoserine
BBD27_RS09225	COG1115	amino acid carrier protein
BBD27_RS09250	COG0737	Belongs to the 5'-nucleotidase family
BBD27_RS09265	COG3104	oligopeptide transport
BBD27_RS09280	COG0284	orotidine-5'-phosphate decarboxylase activity
BBD27_RS09295	COG1567	CRISPR-associated RAMP protein, Csm4 family
BBD27_RS09300	COG1337	RAMP superfamily
BBD27_RS09320	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBD27_RS09325	COG1468	defense response to virus
BBD27_RS09325	COG1518	maintenance of DNA repeat elements
BBD27_RS09330	COG0167	dihydroorotate dehydrogenase activity
BBD27_RS09340	COG0047	phosphoribosylformylglycinamidine synthase activity
BBD27_RS09350	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BBD27_RS09370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBD27_RS09395	COG1063	alcohol dehydrogenase
BBD27_RS09405	COG1230	cation diffusion facilitator family transporter
BBD27_RS09440	COG3527	Alpha-acetolactate decarboxylase
BBD27_RS09445	COG0028	Belongs to the TPP enzyme family
BBD27_RS09455	COG0010	Belongs to the arginase family
BBD27_RS09460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBD27_RS09465	COG3328	transposase activity
BBD27_RS09475	COG1396	sequence-specific DNA binding
BBD27_RS09525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBD27_RS09530	COG0758	DNA mediated transformation
BBD27_RS09535	COG1940	carbohydrate kinase activity
BBD27_RS09545	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BBD27_RS09555	COG1827	regulation of RNA biosynthetic process
BBD27_RS09565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBD27_RS09575	COG2188	Transcriptional regulator
BBD27_RS09580	COG0519	Catalyzes the synthesis of GMP from XMP
BBD27_RS09580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BBD27_RS09585	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BBD27_RS09600	COG1064	alcohol dehydrogenase
BBD27_RS09620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBD27_RS09625	COG1126	abc transporter atp-binding protein
BBD27_RS09630	COG0765	amino acid transport
BBD27_RS09635	COG2824	Alkylphosphonate utilization operon protein PhnA
BBD27_RS09640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBD27_RS09655	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBD27_RS09655	COG3942	CHAP domain
BBD27_RS09695	COG4975	Glucose uptake
BBD27_RS09700	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BBD27_RS09725	COG0626	cystathionine gamma-synthase activity
BBD27_RS09730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBD27_RS09740	COG3328	transposase activity
BBD27_RS09745	COG2217	Heavy metal translocating P-type atpase
BBD27_RS09760	COG2801	Transposase and inactivated derivatives
BBD27_RS09770	COG1278	Cold shock